RPS19P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.91660256
2viral transcription (GO:0019083)7.04512791
3ribosomal small subunit biogenesis (GO:0042274)6.99154109
4translational termination (GO:0006415)6.69215031
5maturation of SSU-rRNA (GO:0030490)6.34395933
6translational elongation (GO:0006414)5.72633888
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.71736468
8protein targeting to ER (GO:0045047)5.66049061
9cotranslational protein targeting to membrane (GO:0006613)5.62300840
10establishment of protein localization to endoplasmic reticulum (GO:0072599)5.39132225
11protein localization to endoplasmic reticulum (GO:0070972)5.36629065
12positive regulation of respiratory burst (GO:0060267)5.28511792
13cellular protein complex disassembly (GO:0043624)5.05786279
14viral life cycle (GO:0019058)5.05551293
15behavioral response to nicotine (GO:0035095)4.93904974
16ATP synthesis coupled proton transport (GO:0015986)4.90289002
17energy coupled proton transport, down electrochemical gradient (GO:0015985)4.90289002
18regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.77706493
19DNA deamination (GO:0045006)4.72982007
20cytidine catabolic process (GO:0006216)4.65640335
21cytidine deamination (GO:0009972)4.65640335
22cytidine metabolic process (GO:0046087)4.65640335
23nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.58575674
24mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.22155143
25protein complex disassembly (GO:0043241)4.17779337
26translational initiation (GO:0006413)4.13586853
27ribosomal large subunit biogenesis (GO:0042273)3.93331819
28central nervous system myelination (GO:0022010)3.93228622
29axon ensheathment in central nervous system (GO:0032291)3.93228622
30macromolecular complex disassembly (GO:0032984)3.90811055
31pyrimidine ribonucleoside catabolic process (GO:0046133)3.90418103
32mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.81933197
33translation (GO:0006412)3.73383447
34chaperone-mediated protein transport (GO:0072321)3.72820282
35regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.70900314
36negative regulation of T cell differentiation in thymus (GO:0033085)3.68864085
37protein targeting to membrane (GO:0006612)3.68410446
38protein complex biogenesis (GO:0070271)3.61651467
39water-soluble vitamin biosynthetic process (GO:0042364)3.56657384
40respiratory electron transport chain (GO:0022904)3.54002537
41regulation of respiratory burst (GO:0060263)3.53529917
42electron transport chain (GO:0022900)3.52279009
43establishment of protein localization to mitochondrial membrane (GO:0090151)3.49545087
44mitochondrial respiratory chain complex I assembly (GO:0032981)3.40153211
45NADH dehydrogenase complex assembly (GO:0010257)3.40153211
46mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.40153211
47axoneme assembly (GO:0035082)3.25491199
48negative regulation of oligodendrocyte differentiation (GO:0048715)3.24935830
49mitochondrial respiratory chain complex assembly (GO:0033108)3.17705293
50nuclear-transcribed mRNA catabolic process (GO:0000956)3.17174869
51protein neddylation (GO:0045116)3.11094904
52nonmotile primary cilium assembly (GO:0035058)3.05403677
53eosinophil chemotaxis (GO:0048245)3.05204184
54mRNA catabolic process (GO:0006402)3.02288535
55cellular component biogenesis (GO:0044085)2.98097808
56GTP biosynthetic process (GO:0006183)2.97814333
57positive regulation of T cell apoptotic process (GO:0070234)2.97724932
58purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.96242622
59ATP biosynthetic process (GO:0006754)2.95746293
60ribonucleoprotein complex biogenesis (GO:0022613)2.94044910
61purine nucleoside triphosphate biosynthetic process (GO:0009145)2.89520163
62termination of RNA polymerase III transcription (GO:0006386)2.89069367
63transcription elongation from RNA polymerase III promoter (GO:0006385)2.89069367
64response to gravity (GO:0009629)2.86956806
65regulation of guanylate cyclase activity (GO:0031282)2.86880418
66epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.84677177
67negative regulation of astrocyte differentiation (GO:0048712)2.84532284
68adaptation of signaling pathway (GO:0023058)2.79324295
69eosinophil migration (GO:0072677)2.75221473
70synaptic transmission, cholinergic (GO:0007271)2.72792212
71RNA catabolic process (GO:0006401)2.67378434
72hydrogen ion transmembrane transport (GO:1902600)2.66785222
73RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.66532126
74tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.66532126
75antibacterial humoral response (GO:0019731)2.64794188
76regulation of cilium movement (GO:0003352)2.61211466
77activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.60362293
78pattern specification involved in kidney development (GO:0061004)2.57764138
79protein-cofactor linkage (GO:0018065)2.57150588
80positive regulation of defense response to virus by host (GO:0002230)2.56721505
81somite development (GO:0061053)2.55587576
82fucose catabolic process (GO:0019317)2.54534057
83L-fucose metabolic process (GO:0042354)2.54534057
84L-fucose catabolic process (GO:0042355)2.54534057
85retina homeostasis (GO:0001895)2.52788110
86cilium movement (GO:0003341)2.48756962
87ribonucleoside triphosphate biosynthetic process (GO:0009201)2.48440443
88establishment of protein localization to membrane (GO:0090150)2.47790180
89ubiquinone biosynthetic process (GO:0006744)2.46581192
90proton transport (GO:0015992)2.45515404
91killing of cells of other organism (GO:0031640)2.44900791
92disruption of cells of other organism (GO:0044364)2.44900791
93regulation of antigen processing and presentation (GO:0002577)2.44664267
94phosphatidylserine acyl-chain remodeling (GO:0036150)2.43935517
95cellular response to interferon-beta (GO:0035458)2.43622626
96regulation of microtubule-based movement (GO:0060632)2.43404882
97mast cell activation involved in immune response (GO:0002279)2.43385109
98mast cell degranulation (GO:0043303)2.43385109
99auditory receptor cell differentiation (GO:0042491)2.43295800
100negative regulation by host of viral transcription (GO:0043922)2.43152299

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.90361851
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.89885616
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.54078499
4BP1_19119308_ChIP-ChIP_Hs578T_Human3.51021999
5VDR_22108803_ChIP-Seq_LS180_Human3.37748220
6GABP_17652178_ChIP-ChIP_JURKAT_Human2.77693861
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.64040435
8FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.31349597
9ELF1_17652178_ChIP-ChIP_JURKAT_Human2.28587391
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.20080306
11ZNF274_21170338_ChIP-Seq_K562_Hela2.15992659
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.02817423
13ETS1_20019798_ChIP-Seq_JURKAT_Human1.99818146
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.96680939
15JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.93246937
16BMI1_23680149_ChIP-Seq_NPCS_Mouse1.86509925
17CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.82559324
18CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.75719986
19E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.70155439
20CBX2_27304074_Chip-Seq_ESCs_Mouse1.69884273
21EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.61777433
22CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.61472445
23NANOG_20526341_ChIP-Seq_ESCs_Human1.55760625
24TAF2_19829295_ChIP-Seq_ESCs_Human1.55371338
25YY1_22570637_ChIP-Seq_MALME-3M_Human1.55323799
26ERA_21632823_ChIP-Seq_H3396_Human1.55250516
27MYC_19829295_ChIP-Seq_ESCs_Human1.54373053
28BCL6_27268052_Chip-Seq_Bcells_Human1.54256542
29IRF8_22096565_ChIP-ChIP_GC-B_Human1.53731896
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.50878147
31VDR_23849224_ChIP-Seq_CD4+_Human1.50476097
32SUZ12_27294783_Chip-Seq_ESCs_Mouse1.48514504
33EZH2_27294783_Chip-Seq_ESCs_Mouse1.44872898
34CTCF_20526341_ChIP-Seq_ESCs_Human1.43657989
35IRF1_19129219_ChIP-ChIP_H3396_Human1.42922643
36JARID2_20064375_ChIP-Seq_MESCs_Mouse1.42699827
37EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.37461082
38EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.37316903
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.34332691
40CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.33526936
41MYC_18940864_ChIP-ChIP_HL60_Human1.33500367
42IKZF1_21737484_ChIP-ChIP_HCT116_Human1.32823854
43GATA3_21878914_ChIP-Seq_MCF-7_Human1.32031208
44EED_16625203_ChIP-ChIP_MESCs_Mouse1.31475696
45FOXA1_27270436_Chip-Seq_PROSTATE_Human1.29552680
46FOXA1_25329375_ChIP-Seq_VCAP_Human1.29552680
47NCOR_22424771_ChIP-Seq_293T_Human1.28727267
48HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.28143116
49AUTS2_25519132_ChIP-Seq_293T-REX_Human1.26296539
50PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.25194668
51JARID2_20075857_ChIP-Seq_MESCs_Mouse1.24915078
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.22604927
53RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.20423236
54P53_21459846_ChIP-Seq_SAOS-2_Human1.20062974
55SA1_27219007_Chip-Seq_Bcells_Human1.19844276
56TP53_22573176_ChIP-Seq_HFKS_Human1.19821317
57TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19016134
58SRY_22984422_ChIP-ChIP_TESTIS_Rat1.17898446
59E2F1_20622854_ChIP-Seq_HELA_Human1.17337791
60P300_27268052_Chip-Seq_Bcells_Human1.16505865
61MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16017076
62AR_20517297_ChIP-Seq_VCAP_Human1.15043489
63FOXH1_21741376_ChIP-Seq_ESCs_Human1.14421930
64CTCF_27219007_Chip-Seq_Bcells_Human1.14092425
65ETV2_25802403_ChIP-Seq_MESCs_Mouse1.11466353
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.10596173
67TDRD3_21172665_ChIP-Seq_MCF-7_Human1.09445034
68MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.08841224
69POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.08273008
70RBPJ_22232070_ChIP-Seq_NCS_Mouse1.08101490
71CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.06032184
72GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.05555178
73TTF2_22483619_ChIP-Seq_HELA_Human1.03044847
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.02927675
75POU5F1_16153702_ChIP-ChIP_HESCs_Human1.02062982
76SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.01099481
77TP53_20018659_ChIP-ChIP_R1E_Mouse1.00339508
78FUS_26573619_Chip-Seq_HEK293_Human0.99618103
79PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.99158998
80REST_21632747_ChIP-Seq_MESCs_Mouse0.98381960
81SOX2_21211035_ChIP-Seq_LN229_Human0.97240890
82LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.97237082
83CTCF_18555785_ChIP-Seq_MESCs_Mouse0.97093859
84XRN2_22483619_ChIP-Seq_HELA_Human0.96788664
85BCOR_27268052_Chip-Seq_Bcells_Human0.96738263
86RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.95248146
87MYC_18358816_ChIP-ChIP_MESCs_Mouse0.93640927
88RNF2_27304074_Chip-Seq_NSC_Mouse0.93431204
89RAC3_21632823_ChIP-Seq_H3396_Human0.92712983
90RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.92670868
91BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.92658596
92PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.92419026
93FOXP3_21729870_ChIP-Seq_TREG_Human0.91897709
94KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.91737600
95PCGF2_27294783_Chip-Seq_ESCs_Mouse0.91547134
96FOXP1_21924763_ChIP-Seq_HESCs_Human0.90737490
97MYC_18555785_ChIP-Seq_MESCs_Mouse0.90128260
98TET1_21451524_ChIP-Seq_MESCs_Mouse0.89479948
99FOXH1_21741376_ChIP-Seq_EPCs_Human0.89428921
100RNF2_27304074_Chip-Seq_ESCs_Mouse0.87843950

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation7.10223365
2MP0006292_abnormal_olfactory_placode3.36795159
3MP0008789_abnormal_olfactory_epithelium3.05312675
4MP0002653_abnormal_ependyma_morphology2.61680883
5MP0004147_increased_porphyrin_level2.43485335
6MP0003136_yellow_coat_color2.35648346
7MP0005360_urolithiasis2.25590217
8MP0005499_abnormal_olfactory_system2.25227519
9MP0005394_taste/olfaction_phenotype2.25227519
10MP0004885_abnormal_endolymph2.22420253
11MP0003787_abnormal_imprinting2.14960917
12MP0005671_abnormal_response_to2.14741731
13MP0001485_abnormal_pinna_reflex1.95370240
14MP0002876_abnormal_thyroid_physiology1.90184503
15MP0008872_abnormal_physiological_respon1.82506393
16MP0005377_hearing/vestibular/ear_phenot1.82282488
17MP0003878_abnormal_ear_physiology1.82282488
18MP0008875_abnormal_xenobiotic_pharmacok1.74215914
19MP0002277_abnormal_respiratory_mucosa1.69203835
20MP0001293_anophthalmia1.68927875
21MP0004142_abnormal_muscle_tone1.62546987
22MP0003646_muscle_fatigue1.60705977
23MP0004145_abnormal_muscle_electrophysio1.59856302
24MP0006072_abnormal_retinal_apoptosis1.57466008
25MP0005645_abnormal_hypothalamus_physiol1.53846749
26MP0003123_paternal_imprinting1.52271554
27MP0004742_abnormal_vestibular_system1.50951039
28MP0002139_abnormal_hepatobiliary_system1.49023609
29MP0001873_stomach_inflammation1.43642419
30MP0008877_abnormal_DNA_methylation1.42921024
31MP0001835_abnormal_antigen_presentation1.39471287
32MP0005387_immune_system_phenotype1.37905561
33MP0001790_abnormal_immune_system1.37905561
34MP0000049_abnormal_middle_ear1.37354765
35MP0010155_abnormal_intestine_physiology1.33001099
36MP0002095_abnormal_skin_pigmentation1.31600693
37MP0002102_abnormal_ear_morphology1.30975303
38MP0009333_abnormal_splenocyte_physiolog1.26559283
39MP0001968_abnormal_touch/_nociception1.25294137
40MP0002163_abnormal_gland_morphology1.25032086
41MP0001905_abnormal_dopamine_level1.24741163
42MP0005551_abnormal_eye_electrophysiolog1.23965558
43MP0001666_abnormal_nutrient_absorption1.23857593
44MP0000685_abnormal_immune_system1.23037854
45MP0005085_abnormal_gallbladder_physiolo1.22602501
46MP0002837_dystrophic_cardiac_calcinosis1.21647568
47MP0009745_abnormal_behavioral_response1.19406636
48MP0005646_abnormal_pituitary_gland1.18177867
49MP0001919_abnormal_reproductive_system1.17592664
50MP0002638_abnormal_pupillary_reflex1.15843746
51MP0001986_abnormal_taste_sensitivity1.15023728
52MP0001765_abnormal_ion_homeostasis1.14924287
53MP0002138_abnormal_hepatobiliary_system1.14209139
54MP0003011_delayed_dark_adaptation1.13917624
55MP0003866_abnormal_defecation1.12724288
56MP0004019_abnormal_vitamin_homeostasis1.11008043
57MP0001800_abnormal_humoral_immune1.10083722
58MP0002272_abnormal_nervous_system1.09742417
59MP0005083_abnormal_biliary_tract1.08732206
60MP0002733_abnormal_thermal_nociception1.08675747
61MP0002148_abnormal_hypersensitivity_rea1.07747343
62MP0005389_reproductive_system_phenotype1.07697437
63MP0005174_abnormal_tail_pigmentation1.05188948
64MP0000490_abnormal_crypts_of1.01751455
65MP0006036_abnormal_mitochondrial_physio0.98503931
66MP0002736_abnormal_nociception_after0.98392350
67MP0000631_abnormal_neuroendocrine_gland0.97618386
68MP0006276_abnormal_autonomic_nervous0.96847625
69MP0002234_abnormal_pharynx_morphology0.95613572
70MP0008775_abnormal_heart_ventricle0.94127823
71MP0003718_maternal_effect0.94074596
72MP0001970_abnormal_pain_threshold0.93914626
73MP0003938_abnormal_ear_development0.93816149
74MP0009785_altered_susceptibility_to0.92184117
75MP0001663_abnormal_digestive_system0.92048856
76MP0005636_abnormal_mineral_homeostasis0.90006506
77MP0005084_abnormal_gallbladder_morpholo0.88810037
78MP0000026_abnormal_inner_ear0.86622359
79MP0010386_abnormal_urinary_bladder0.81170251
80MP0000372_irregular_coat_pigmentation0.81068402
81MP0002723_abnormal_immune_serum0.78910396
82MP0002938_white_spotting0.78349604
83MP0003567_abnormal_fetal_cardiomyocyte0.78244029
84MP0003195_calcinosis0.74444853
85MP0002160_abnormal_reproductive_system0.73971582
86MP0003880_abnormal_central_pattern0.73170590
87MP0000230_abnormal_systemic_arterial0.71513525
88MP0001963_abnormal_hearing_physiology0.71189774
89MP0001440_abnormal_grooming_behavior0.70089595
90MP0005025_abnormal_response_to0.70088871
91MP0002420_abnormal_adaptive_immunity0.69532812
92MP0001764_abnormal_homeostasis0.69256880
93MP0010030_abnormal_orbit_morphology0.69074202
94MP0001819_abnormal_immune_cell0.68663150
95MP0002557_abnormal_social/conspecific_i0.68592212
96MP0003763_abnormal_thymus_physiology0.67961790
97MP0003693_abnormal_embryo_hatching0.66290923
98MP0004133_heterotaxia0.65556538
99MP0005332_abnormal_amino_acid0.65006392
100MP0001501_abnormal_sleep_pattern0.64974896

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.26651600
2Abnormality of cells of the erythroid lineage (HP:0012130)4.85667714
3Aplasia/Hypoplasia of the sacrum (HP:0008517)4.51515544
4Abnormal number of erythroid precursors (HP:0012131)4.25134442
5Acute necrotizing encephalopathy (HP:0006965)3.79239703
6Increased intramyocellular lipid droplets (HP:0012240)3.64947715
7Macrocytic anemia (HP:0001972)3.61480906
8Pancreatic cysts (HP:0001737)3.55449529
9Abnormal respiratory motile cilium morphology (HP:0005938)3.51950808
10Abnormal respiratory epithelium morphology (HP:0012253)3.51950808
11Congenital stationary night blindness (HP:0007642)3.51744308
12Mitochondrial inheritance (HP:0001427)3.43131538
13Increased hepatocellular lipid droplets (HP:0006565)3.37764039
14Abnormal mitochondria in muscle tissue (HP:0008316)3.35824673
15Increased muscle lipid content (HP:0009058)3.31493833
16Acute encephalopathy (HP:0006846)3.31188464
17Lipid accumulation in hepatocytes (HP:0006561)3.27453174
18Abnormal ciliary motility (HP:0012262)3.26357272
19Molar tooth sign on MRI (HP:0002419)3.13754228
20Abnormality of midbrain morphology (HP:0002418)3.13754228
21Decreased activity of mitochondrial respiratory chain (HP:0008972)3.10856789
22Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.10856789
23Maternal diabetes (HP:0009800)3.08614743
24Septo-optic dysplasia (HP:0100842)3.04325756
25Pancreatic fibrosis (HP:0100732)2.98645264
26Increased CSF lactate (HP:0002490)2.94872677
27Progressive macrocephaly (HP:0004481)2.94494890
28Renal Fanconi syndrome (HP:0001994)2.94312077
29True hermaphroditism (HP:0010459)2.91927645
303-Methylglutaconic aciduria (HP:0003535)2.86231309
31Abnormal respiratory motile cilium physiology (HP:0012261)2.84861545
32Nephronophthisis (HP:0000090)2.81756614
33IgG deficiency (HP:0004315)2.74058073
34Stomatitis (HP:0010280)2.62365298
35Colon cancer (HP:0003003)2.56814394
36Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.54835321
37Asplenia (HP:0001746)2.53794869
38Pallor (HP:0000980)2.52908796
39Rib fusion (HP:0000902)2.49681029
40Aplasia/Hypoplasia of the spleen (HP:0010451)2.49247951
41Tubular atrophy (HP:0000092)2.48209683
42Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.47639892
43Concave nail (HP:0001598)2.47157344
44Abnormality of the renal cortex (HP:0011035)2.45577400
45Sclerocornea (HP:0000647)2.43436420
46Abnormal biliary tract physiology (HP:0012439)2.40650027
47Bile duct proliferation (HP:0001408)2.40650027
48Chronic sinusitis (HP:0011109)2.39928720
49Cerebral edema (HP:0002181)2.39387751
50Hyperglycinemia (HP:0002154)2.37464055
51Abnormality of urine glucose concentration (HP:0011016)2.37153847
52Glycosuria (HP:0003076)2.37153847
53Anophthalmia (HP:0000528)2.35952230
54Absent rod-and cone-mediated responses on ERG (HP:0007688)2.35786663
55Abnormality of the renal medulla (HP:0100957)2.33929050
56Anencephaly (HP:0002323)2.32700944
57Hepatocellular necrosis (HP:0001404)2.27395547
58Exercise intolerance (HP:0003546)2.25316901
59Microretrognathia (HP:0000308)2.21348199
60Abnormal rod and cone electroretinograms (HP:0008323)2.19098913
61Increased serum lactate (HP:0002151)2.17382944
62Hyperphosphaturia (HP:0003109)2.14247725
63Absent thumb (HP:0009777)2.13855573
64Methylmalonic aciduria (HP:0012120)2.12717385
65Abolished electroretinogram (ERG) (HP:0000550)2.12117791
66Exertional dyspnea (HP:0002875)2.10028895
67Lactic acidosis (HP:0003128)2.09628686
68Lethargy (HP:0001254)2.08030659
69Congenital, generalized hypertrichosis (HP:0004540)2.05826235
70Optic disc pallor (HP:0000543)2.05367939
71Abnormal number of incisors (HP:0011064)2.04429341
72Hepatic necrosis (HP:0002605)2.02645372
73Pendular nystagmus (HP:0012043)2.01273835
74Hypoplasia of the ulna (HP:0003022)1.93823652
75Abnormality of renal resorption (HP:0011038)1.91827025
76Type 2 muscle fiber atrophy (HP:0003554)1.90934014
77Cystic liver disease (HP:0006706)1.88027836
78Elevated erythrocyte sedimentation rate (HP:0003565)1.87504303
79Abnormal delayed hypersensitivity skin test (HP:0002963)1.86666118
80Rhinitis (HP:0012384)1.84412243
81Partial duplication of thumb phalanx (HP:0009944)1.82447383
82Optic nerve coloboma (HP:0000588)1.82058085
83Confusion (HP:0001289)1.81563634
84Postaxial foot polydactyly (HP:0001830)1.78770878
85Abnormality of glutamine family amino acid metabolism (HP:0010902)1.78373955
86Medial flaring of the eyebrow (HP:0010747)1.77683209
87Chorioretinal atrophy (HP:0000533)1.77194195
88Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.76497891
89Bronchiectasis (HP:0002110)1.76207915
90Stenosis of the external auditory canal (HP:0000402)1.75810971
91Hypoplasia of the radius (HP:0002984)1.75691157
92Methylmalonic acidemia (HP:0002912)1.74914987
93Dynein arm defect of respiratory motile cilia (HP:0012255)1.74841203
94Absent/shortened dynein arms (HP:0200106)1.74841203
95Optic nerve hypoplasia (HP:0000609)1.74666677
96Rectal prolapse (HP:0002035)1.74654549
97Abnormal pupillary function (HP:0007686)1.73081165
98Nonprogressive disorder (HP:0003680)1.71816867
99Abnormal drinking behavior (HP:0030082)1.70361138
100Polydipsia (HP:0001959)1.70361138

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.03807653
2WNK43.75770391
3GRK12.94014056
4ADRBK22.76635840
5MAP2K22.72408170
6VRK22.71609371
7BCKDK2.58839318
8TIE12.46083914
9TESK22.42056679
10TLK12.32539747
11STK392.24226680
12TNK21.95476999
13PINK11.77544021
14DYRK21.76377744
15MAP3K111.62392147
16VRK11.60081648
17MAPK151.53481934
18ZAK1.53111587
19EPHA41.51706491
20CAMKK21.51475286
21NUAK11.51063109
22GRK61.44226046
23PIK3CA1.38760999
24CDK191.37509119
25EPHB21.32629153
26NME21.32129679
27LIMK11.30476807
28TAOK31.30003591
29KDR1.27141144
30MAP4K11.23285245
31BMPR1B1.19421425
32STK161.17724307
33PRKCQ1.17385333
34TEC1.05364496
35MAP3K40.99762652
36ITK0.98256553
37OXSR10.96193574
38BTK0.93996623
39OBSCN0.93075973
40PHKG20.93065895
41PHKG10.93065895
42LRRK20.92705517
43MAP4K20.91558108
44CAMK10.90277109
45CAMKK10.86407424
46DAPK20.85692060
47WNK30.84518400
48MAP2K60.84181941
49WNK10.84162137
50ABL20.81743633
51PRKCG0.81187492
52GRK70.79583065
53DYRK1A0.77164154
54TYRO30.76350678
55NME10.75839674
56MKNK20.74050636
57MAP3K120.73877047
58MUSK0.73592948
59INSRR0.71713411
60IKBKB0.71346559
61DAPK30.68641464
62RPS6KA60.68428061
63ADRBK10.66863968
64MAP2K10.66411890
65PRKACA0.65191336
66ACVR1B0.64461838
67FRK0.64353286
68PASK0.63471875
69NEK90.63440383
70RPS6KA50.61382419
71PIM20.59917994
72TESK10.58091428
73AURKA0.58072586
74MYLK0.57496258
75PRKCZ0.57293245
76CSNK2A20.57198635
77MAP2K70.56499254
78PRKCA0.56084708
79EIF2AK10.54929840
80TAF10.53474568
81FES0.53436873
82SYK0.51421480
83PNCK0.51367682
84BUB10.51014943
85IKBKE0.48868824
86CSNK2A10.48714645
87TSSK60.48306680
88PIM10.48218905
89KIT0.46810576
90PRKCI0.46662752
91GRK50.45407534
92LCK0.45188828
93RPS6KC10.43415964
94RPS6KL10.43415964
95CASK0.42983186
96PRKCH0.41025474
97PRKCD0.39772210
98DYRK1B0.38968969
99PDK20.37693138
100PRKCE0.35512835

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.78885852
2Oxidative phosphorylation_Homo sapiens_hsa001903.45231500
3Asthma_Homo sapiens_hsa053103.28120345
4Parkinsons disease_Homo sapiens_hsa050122.99915330
5Intestinal immune network for IgA production_Homo sapiens_hsa046722.68469139
6Allograft rejection_Homo sapiens_hsa053302.62240707
7Autoimmune thyroid disease_Homo sapiens_hsa053202.61324923
8Linoleic acid metabolism_Homo sapiens_hsa005912.32756812
9Primary immunodeficiency_Homo sapiens_hsa053402.31134856
10Caffeine metabolism_Homo sapiens_hsa002322.26118340
11Graft-versus-host disease_Homo sapiens_hsa053322.25674390
12Fat digestion and absorption_Homo sapiens_hsa049752.13457482
13Cyanoamino acid metabolism_Homo sapiens_hsa004602.11608583
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.03499019
15Alzheimers disease_Homo sapiens_hsa050102.01983980
16Huntingtons disease_Homo sapiens_hsa050162.01644418
17RNA polymerase_Homo sapiens_hsa030201.96975053
18Cardiac muscle contraction_Homo sapiens_hsa042601.86872697
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.85864153
20Type I diabetes mellitus_Homo sapiens_hsa049401.84452648
21Antigen processing and presentation_Homo sapiens_hsa046121.75679263
22Proteasome_Homo sapiens_hsa030501.70389154
23Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.49420664
24Chemical carcinogenesis_Homo sapiens_hsa052041.47051845
25Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.46474267
26Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.44901560
27Arachidonic acid metabolism_Homo sapiens_hsa005901.44366686
28Phototransduction_Homo sapiens_hsa047441.35087836
29Protein export_Homo sapiens_hsa030601.32279315
30Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.30773775
31Sulfur relay system_Homo sapiens_hsa041221.30426451
32Vitamin digestion and absorption_Homo sapiens_hsa049771.26357024
33Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.22798722
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.18680454
35Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.14674614
36Tryptophan metabolism_Homo sapiens_hsa003801.13868006
37Retinol metabolism_Homo sapiens_hsa008301.09182537
38Ether lipid metabolism_Homo sapiens_hsa005651.05446807
39Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.00421369
40Rheumatoid arthritis_Homo sapiens_hsa053231.00381822
41Pyrimidine metabolism_Homo sapiens_hsa002400.99139122
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.97989738
43Viral myocarditis_Homo sapiens_hsa054160.96586341
44Nitrogen metabolism_Homo sapiens_hsa009100.94998588
45Steroid hormone biosynthesis_Homo sapiens_hsa001400.94368269
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.91379746
47Hematopoietic cell lineage_Homo sapiens_hsa046400.89435885
48Peroxisome_Homo sapiens_hsa041460.86378803
49Propanoate metabolism_Homo sapiens_hsa006400.84142078
50Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.82592806
51Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.81338934
52Mineral absorption_Homo sapiens_hsa049780.79016187
53Glutathione metabolism_Homo sapiens_hsa004800.75678378
54Homologous recombination_Homo sapiens_hsa034400.73921821
55Fanconi anemia pathway_Homo sapiens_hsa034600.72944838
56Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.72865211
57Staphylococcus aureus infection_Homo sapiens_hsa051500.69864304
58RNA degradation_Homo sapiens_hsa030180.67739887
59Folate biosynthesis_Homo sapiens_hsa007900.67346458
60Sulfur metabolism_Homo sapiens_hsa009200.65642179
61Drug metabolism - other enzymes_Homo sapiens_hsa009830.65366855
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.64470145
63Maturity onset diabetes of the young_Homo sapiens_hsa049500.63105000
64Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60989574
65Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.58975501
66Metabolic pathways_Homo sapiens_hsa011000.56775196
67Regulation of autophagy_Homo sapiens_hsa041400.56678164
68Butanoate metabolism_Homo sapiens_hsa006500.54375681
69Purine metabolism_Homo sapiens_hsa002300.53444047
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53397413
71Systemic lupus erythematosus_Homo sapiens_hsa053220.51415958
72Primary bile acid biosynthesis_Homo sapiens_hsa001200.40458052
73Carbohydrate digestion and absorption_Homo sapiens_hsa049730.39269619
74Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.39264381
75Fatty acid degradation_Homo sapiens_hsa000710.38710351
76Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.37627768
77Ovarian steroidogenesis_Homo sapiens_hsa049130.35837957
78Olfactory transduction_Homo sapiens_hsa047400.35588066
79Glycerolipid metabolism_Homo sapiens_hsa005610.35530897
80Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.34033482
81Protein digestion and absorption_Homo sapiens_hsa049740.33156026
82Basal transcription factors_Homo sapiens_hsa030220.30061469
83Renin-angiotensin system_Homo sapiens_hsa046140.29089236
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.24996514
85Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.24724029
86Starch and sucrose metabolism_Homo sapiens_hsa005000.23847757
87Cysteine and methionine metabolism_Homo sapiens_hsa002700.22990948
88Nicotine addiction_Homo sapiens_hsa050330.22494061
89Arginine and proline metabolism_Homo sapiens_hsa003300.22414528
90T cell receptor signaling pathway_Homo sapiens_hsa046600.20432097
91Pancreatic secretion_Homo sapiens_hsa049720.19551331
92beta-Alanine metabolism_Homo sapiens_hsa004100.19398507
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.19182287
94Tyrosine metabolism_Homo sapiens_hsa003500.18422059
95NF-kappa B signaling pathway_Homo sapiens_hsa040640.17465988
96Insulin secretion_Homo sapiens_hsa049110.16565946
97One carbon pool by folate_Homo sapiens_hsa006700.16188176
98Taste transduction_Homo sapiens_hsa047420.16028476
99Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.15723435
100Serotonergic synapse_Homo sapiens_hsa047260.15520480

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