RPS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.20522935
2* viral transcription (GO:0019083)5.84833458
3* translational termination (GO:0006415)5.70337198
4DNA unwinding involved in DNA replication (GO:0006268)5.37821281
5* translational elongation (GO:0006414)5.18057766
6maturation of SSU-rRNA (GO:0030490)5.16957776
7* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.78243826
8ribosomal small subunit biogenesis (GO:0042274)4.75123516
9* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.71529549
10* translational initiation (GO:0006413)4.71410319
11DNA strand elongation involved in DNA replication (GO:0006271)4.66066553
12* protein targeting to ER (GO:0045047)4.58846887
13formation of translation preinitiation complex (GO:0001731)4.57926007
14* cotranslational protein targeting to membrane (GO:0006613)4.57011913
15folic acid-containing compound biosynthetic process (GO:0009396)4.51180618
16* cellular protein complex disassembly (GO:0043624)4.42940319
17* viral life cycle (GO:0019058)4.42579300
18DNA strand elongation (GO:0022616)4.41765061
19DNA replication initiation (GO:0006270)4.41461944
20* establishment of protein localization to endoplasmic reticulum (GO:0072599)4.36487458
21ribosomal large subunit biogenesis (GO:0042273)4.32903591
22* protein localization to endoplasmic reticulum (GO:0070972)4.27026808
23telomere maintenance via semi-conservative replication (GO:0032201)4.19040415
24* protein complex disassembly (GO:0043241)4.08945568
25DNA deamination (GO:0045006)4.02199007
26protein localization to kinetochore (GO:0034501)3.95347144
27proline biosynthetic process (GO:0006561)3.88955863
28regulation of mammary gland epithelial cell proliferation (GO:0033599)3.87371190
29IMP biosynthetic process (GO:0006188)3.86003957
30* macromolecular complex disassembly (GO:0032984)3.81317861
31ribonucleoprotein complex biogenesis (GO:0022613)3.79116876
32nucleobase biosynthetic process (GO:0046112)3.77708476
33spliceosomal tri-snRNP complex assembly (GO:0000244)3.66889939
34mitotic nuclear envelope disassembly (GO:0007077)3.65288670
35* nuclear-transcribed mRNA catabolic process (GO:0000956)3.64964479
36telomere maintenance via recombination (GO:0000722)3.56139135
37IMP metabolic process (GO:0046040)3.51527735
38pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.47289171
39* mRNA catabolic process (GO:0006402)3.46621869
40negative regulation of RNA splicing (GO:0033119)3.45740203
41negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.45377364
42DNA replication-dependent nucleosome assembly (GO:0006335)3.44707288
43DNA replication-dependent nucleosome organization (GO:0034723)3.44707288
44protein localization to chromosome, centromeric region (GO:0071459)3.42490566
45* RNA catabolic process (GO:0006401)3.41870355
46cellular component biogenesis (GO:0044085)3.41448050
47regulation of translational fidelity (GO:0006450)3.40605034
48membrane disassembly (GO:0030397)3.38605169
49nuclear envelope disassembly (GO:0051081)3.38605169
50mitotic recombination (GO:0006312)3.37575174
51ribosome biogenesis (GO:0042254)3.31757086
52telomere maintenance via telomere lengthening (GO:0010833)3.29848797
53viral mRNA export from host cell nucleus (GO:0046784)3.29804856
54nucleosome disassembly (GO:0006337)3.27934496
55protein-DNA complex disassembly (GO:0032986)3.27934496
56* translation (GO:0006412)3.27129543
57heterochromatin organization (GO:0070828)3.25770411
58rRNA processing (GO:0006364)3.24668270
59DNA duplex unwinding (GO:0032508)3.22930527
60DNA geometric change (GO:0032392)3.19642686
61pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.18863870
62pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.17831653
63nuclear pore organization (GO:0006999)3.17763052
64purine nucleobase biosynthetic process (GO:0009113)3.16893239
65ribosome assembly (GO:0042255)3.15809345
66nucleotide-excision repair, DNA gap filling (GO:0006297)3.15529508
67DNA replication checkpoint (GO:0000076)3.15086980
68pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.15024601
69rRNA metabolic process (GO:0016072)3.13248987
70regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.12393395
71establishment of integrated proviral latency (GO:0075713)3.09539977
72rRNA transcription (GO:0009303)3.06449261
73nucleobase-containing small molecule interconversion (GO:0015949)3.04829317
74histone arginine methylation (GO:0034969)3.02841482
75* establishment of protein localization to membrane (GO:0090150)3.01751830
76* protein targeting to membrane (GO:0006612)3.01274191
77nuclear pore complex assembly (GO:0051292)2.98708304
78translesion synthesis (GO:0019985)2.98450187
79pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.97643633
80pyrimidine nucleotide catabolic process (GO:0006244)2.97316418
81mitotic metaphase plate congression (GO:0007080)2.96473553
82pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.95317736
83UTP biosynthetic process (GO:0006228)2.94363389
84DNA topological change (GO:0006265)2.93411060
85spliceosomal snRNP assembly (GO:0000387)2.92447507
86negative regulation of mRNA processing (GO:0050686)2.92111031
87regulation of translational termination (GO:0006449)2.91395018
88negative regulation of erythrocyte differentiation (GO:0045647)2.91008824
89pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.90788302
90guanosine-containing compound biosynthetic process (GO:1901070)2.89313658
91peptidyl-arginine omega-N-methylation (GO:0035247)2.85630805
92regulation of histone H3-K9 methylation (GO:0051570)2.85213375
93pseudouridine synthesis (GO:0001522)2.84620369
94pteridine-containing compound biosynthetic process (GO:0042559)2.84378429
95chromatin remodeling at centromere (GO:0031055)2.84177553
96regulation of protein heterodimerization activity (GO:0043497)2.82202218
97ncRNA 3-end processing (GO:0043628)2.81896318
98CENP-A containing nucleosome assembly (GO:0034080)2.80638187
99peptidyl-arginine methylation (GO:0018216)2.79490088
100peptidyl-arginine N-methylation (GO:0035246)2.79490088
101mRNA splicing, via spliceosome (GO:0000398)2.78410408
102RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.78410408
103DNA replication-independent nucleosome assembly (GO:0006336)2.77026426
104DNA replication-independent nucleosome organization (GO:0034724)2.77026426
105regulation of gene silencing by RNA (GO:0060966)2.76865865
106regulation of posttranscriptional gene silencing (GO:0060147)2.76865865
107regulation of gene silencing by miRNA (GO:0060964)2.76865865
108RNA splicing, via transesterification reactions (GO:0000375)2.76841084
109pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.75483110
110chromatin assembly or disassembly (GO:0006333)2.75114362
111regulation of chromatin binding (GO:0035561)2.74883414
112mRNA stabilization (GO:0048255)2.72881707
113RNA stabilization (GO:0043489)2.72881707
114pentose-phosphate shunt (GO:0006098)2.72766688
115mitotic chromosome condensation (GO:0007076)2.71725095
1163-UTR-mediated mRNA stabilization (GO:0070935)2.71554735
117CTP metabolic process (GO:0046036)2.71245714
118CTP biosynthetic process (GO:0006241)2.71245714
119T cell apoptotic process (GO:0070231)2.70346248
120negative regulation of mRNA metabolic process (GO:1903312)2.69714628
121mitotic sister chromatid segregation (GO:0000070)2.69583046
122* protein targeting (GO:0006605)2.68001217
123folic acid metabolic process (GO:0046655)2.67716429
124positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling2.67409815
125UTP metabolic process (GO:0046051)2.67314529
126termination of RNA polymerase II transcription (GO:0006369)2.67240570
127nuclear envelope organization (GO:0006998)2.65830279
128deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.64823405
129base-excision repair (GO:0006284)2.62615472
130metaphase plate congression (GO:0051310)2.62590105
131* establishment of protein localization to organelle (GO:0072594)2.62185290
132regulation of spindle organization (GO:0090224)2.61664931
133chromatin assembly (GO:0031497)2.60702957
134postreplication repair (GO:0006301)2.60227755
135dosage compensation (GO:0007549)2.57547268
136L-serine metabolic process (GO:0006563)2.57127470
137apoptotic process involved in morphogenesis (GO:0060561)2.55085090
138negative regulation of DNA-templated transcription, elongation (GO:0032785)2.52739088
139regulation of RNA export from nucleus (GO:0046831)2.52677735
140ribonucleoprotein complex assembly (GO:0022618)2.49439678
141* gene expression (GO:0010467)2.45273540

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.86137516
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.15529151
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.10936357
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.50538542
5E2F4_17652178_ChIP-ChIP_JURKAT_Human3.03829166
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.98252492
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.63667613
8* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.59838761
9MYC_22102868_ChIP-Seq_BL_Human2.58507090
10* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.57018894
11EGR1_19374776_ChIP-ChIP_THP-1_Human2.43676463
12* XRN2_22483619_ChIP-Seq_HELA_Human2.35447355
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.32971160
14EST1_17652178_ChIP-ChIP_JURKAT_Human2.25529780
15* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.10891793
16GABP_17652178_ChIP-ChIP_JURKAT_Human2.09250090
17* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.04781030
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.01939804
19CREB1_15753290_ChIP-ChIP_HEK293T_Human2.01078354
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.94129294
21TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.93283460
22VDR_23849224_ChIP-Seq_CD4+_Human1.85622532
23VDR_21846776_ChIP-Seq_THP-1_Human1.84242294
24SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83798431
25ELF1_17652178_ChIP-ChIP_JURKAT_Human1.80101867
26E2F1_21310950_ChIP-Seq_MCF-7_Human1.75983724
27CIITA_25753668_ChIP-Seq_RAJI_Human1.75140883
28AR_21909140_ChIP-Seq_LNCAP_Human1.74676164
29* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.74446001
30LXR_22292898_ChIP-Seq_THP-1_Human1.73116759
31DCP1A_22483619_ChIP-Seq_HELA_Human1.71907429
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.70582654
33* FOXP3_21729870_ChIP-Seq_TREG_Human1.70260245
34* TTF2_22483619_ChIP-Seq_HELA_Human1.67281331
35SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.64601351
36* GABP_19822575_ChIP-Seq_HepG2_Human1.64096931
37* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.59756959
38MYCN_18555785_ChIP-Seq_MESCs_Mouse1.59661890
39MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.58380747
40MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57951241
41NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.56626986
42POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.51797746
43RACK7_27058665_Chip-Seq_MCF-7_Human1.49614723
44PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.49290573
45TET1_21451524_ChIP-Seq_MESCs_Mouse1.45519237
46* TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.45442414
47* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.44454821
48STAT3_1855785_ChIP-Seq_MESCs_Mouse1.43604407
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.43168950
50ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.43108954
51CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.39446620
52KDM5A_27292631_Chip-Seq_BREAST_Human1.37486325
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.37203572
54NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.36687058
55KDM2B_26808549_Chip-Seq_DND41_Human1.34543090
56CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.34144553
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.33806531
58PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.32354800
59P68_20966046_ChIP-Seq_HELA_Human1.30641988
60SRY_22984422_ChIP-ChIP_TESTIS_Rat1.29693643
61KDM2B_26808549_Chip-Seq_SUP-B15_Human1.29328978
62POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.28920297
63ERG_20887958_ChIP-Seq_HPC-7_Mouse1.28080191
64SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.27237699
65DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.26336869
66HOXB4_20404135_ChIP-ChIP_EML_Mouse1.26144793
67ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.25301238
68* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.25196038
69SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.24948816
70ESR1_15608294_ChIP-ChIP_MCF-7_Human1.24371296
71NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.23871136
72ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.20406063
73KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.19976277
74E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.18603920
75* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.18521881
76NCOR1_26117541_ChIP-Seq_K562_Human1.18406005
77ELK1_19687146_ChIP-ChIP_HELA_Human1.18182182
78TFEB_21752829_ChIP-Seq_HELA_Human1.16096732
79SA1_27219007_Chip-Seq_ERYTHROID_Human1.14824321
80YY1_21170310_ChIP-Seq_MESCs_Mouse1.14500381
81YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14132055
82ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.14059258
83* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.12515206
84SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.12132780
85KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.10352412
86* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09838038
87MAF_26560356_Chip-Seq_TH1_Human1.08959658
88* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.08677649
89UTX_26944678_Chip-Seq_JUKART_Human1.07900844
90TP63_17297297_ChIP-ChIP_HaCaT_Human1.07454222
91* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.06589440
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.06264694
93CTCF_27219007_Chip-Seq_ERYTHROID_Human1.05841891
94CTCF_18555785_ChIP-Seq_MESCs_Mouse1.05582796
95* FOXP1_21924763_ChIP-Seq_HESCs_Human1.05190684
96NOTCH1_21737748_ChIP-Seq_TLL_Human1.04691689
97FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.04673578
98SPI1_23547873_ChIP-Seq_NB4_Human1.04447283
99SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.04234488
100ELF1_20517297_ChIP-Seq_JURKAT_Human1.03363043
101CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.03248287
102ELK3_25401928_ChIP-Seq_HUVEC_Human1.03019566
103TCF7_22412390_ChIP-Seq_EML_Mouse1.01951224
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.01739614
105TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.01576621
106ZNF263_19887448_ChIP-Seq_K562_Human1.00833703
107TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.00547608
108CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98940070
109SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.98476596
110KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.98080012
111CREB1_26743006_Chip-Seq_LNCaP_Human0.95812033
112SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94873786
113POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.94579896
114SCL_19346495_ChIP-Seq_HPC-7_Human0.94579765
115MAF_26560356_Chip-Seq_TH2_Human0.92858265
116HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92371240
117TP63_19390658_ChIP-ChIP_HaCaT_Human0.91130692
118MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.90566735
119* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.90551240
120KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.90428268
121GATA1_22383799_ChIP-Seq_G1ME_Mouse0.89183827
122RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.88909379
123ATF3_27146783_Chip-Seq_COLON_Human0.88718281
124SRF_21415370_ChIP-Seq_HL-1_Mouse0.87775371
125VDR_24763502_ChIP-Seq_THP-1_Human0.87750067
126MYB_21317192_ChIP-Seq_ERMYB_Mouse0.87737555
127CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.87546649
128BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.86887102

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.46501658
2MP0004957_abnormal_blastocyst_morpholog3.94444417
3MP0003111_abnormal_nucleus_morphology3.68765677
4MP0010094_abnormal_chromosome_stability3.56470700
5MP0003077_abnormal_cell_cycle3.41718258
6MP0010352_gastrointestinal_tract_polyps2.98139693
7MP0002396_abnormal_hematopoietic_system2.90725206
8MP0008057_abnormal_DNA_replication2.57173221
9MP0008007_abnormal_cellular_replicative2.47486298
10MP0004185_abnormal_adipocyte_glucose2.39680189
11MP0000678_abnormal_parathyroid_gland2.26659746
12MP0001730_embryonic_growth_arrest2.24858023
13MP0008058_abnormal_DNA_repair2.21512504
14MP0004808_abnormal_hematopoietic_stem2.11624850
15MP0000490_abnormal_crypts_of2.10136052
16MP0000350_abnormal_cell_proliferation2.08803124
17MP0008932_abnormal_embryonic_tissue1.97843375
18MP0005451_abnormal_body_composition1.96232846
19MP0004858_abnormal_nervous_system1.94979634
20MP0002249_abnormal_larynx_morphology1.91492479
21MP0010307_abnormal_tumor_latency1.91273779
22MP0003123_paternal_imprinting1.80758396
23MP0003763_abnormal_thymus_physiology1.79536915
24MP0003705_abnormal_hypodermis_morpholog1.75281234
25MP0005397_hematopoietic_system_phenotyp1.72843109
26MP0001545_abnormal_hematopoietic_system1.72843109
27MP0009333_abnormal_splenocyte_physiolog1.71937260
28MP0004233_abnormal_muscle_weight1.71818247
29MP0006054_spinal_hemorrhage1.66779203
30MP0001697_abnormal_embryo_size1.60851141
31MP0002163_abnormal_gland_morphology1.59917966
32MP0002080_prenatal_lethality1.57244944
33MP0002019_abnormal_tumor_incidence1.55083318
34MP0001672_abnormal_embryogenesis/_devel1.54622485
35MP0005380_embryogenesis_phenotype1.54622485
36MP0006292_abnormal_olfactory_placode1.53970334
37MP0005076_abnormal_cell_differentiation1.53689060
38MP0002398_abnormal_bone_marrow1.50250768
39MP0003984_embryonic_growth_retardation1.46478032
40MP0002796_impaired_skin_barrier1.46245833
41MP0000703_abnormal_thymus_morphology1.46001135
42MP0004197_abnormal_fetal_growth/weight/1.45716314
43MP0000313_abnormal_cell_death1.44643737
44MP0009278_abnormal_bone_marrow1.44275962
45MP0002086_abnormal_extraembryonic_tissu1.43878868
46MP0002088_abnormal_embryonic_growth/wei1.43434505
47MP0000685_abnormal_immune_system1.40747741
48MP0002722_abnormal_immune_system1.39207111
49MP0001348_abnormal_lacrimal_gland1.38777195
50MP0002085_abnormal_embryonic_tissue1.38350527
51MP0002084_abnormal_developmental_patter1.36842977
52MP0000858_altered_metastatic_potential1.29670288
53MP0003315_abnormal_perineum_morphology1.29624685
54MP0000689_abnormal_spleen_morphology1.29106991
55MP0003786_premature_aging1.27364483
56MP0003567_abnormal_fetal_cardiomyocyte1.27010460
57MP0005666_abnormal_adipose_tissue1.24255114
58MP0003806_abnormal_nucleotide_metabolis1.22998475
59MP0000537_abnormal_urethra_morphology1.22841007
60MP0002429_abnormal_blood_cell1.17553648
61MP0001346_abnormal_lacrimal_gland1.17427453
62MP0010030_abnormal_orbit_morphology1.17317945
63MP0000681_abnormal_thyroid_gland1.16807905
64MP0005023_abnormal_wound_healing1.13101103
65MP0003566_abnormal_cell_adhesion1.12244760
66MP0009379_abnormal_foot_pigmentation1.09192823
67MP0000716_abnormal_immune_system1.06335057
68MP0001293_anophthalmia1.04741651
69MP0005623_abnormal_meninges_morphology1.04276809
70MP0002697_abnormal_eye_size1.03798403
71MP0001800_abnormal_humoral_immune1.01516113
72MP0004264_abnormal_extraembryonic_tissu1.01432709
73MP0003942_abnormal_urinary_system1.00494301
74MP0008260_abnormal_autophagy1.00418512
75MP0003303_peritoneal_inflammation1.00136443
76MP0010234_abnormal_vibrissa_follicle1.00069514
77MP0002160_abnormal_reproductive_system1.00034814
78MP0000477_abnormal_intestine_morphology0.98951547
79MP0004782_abnormal_surfactant_physiolog0.98873381
80MP0009053_abnormal_anal_canal0.97527708
81MP0002166_altered_tumor_susceptibility0.97345859
82MP0001661_extended_life_span0.96719898
83MP0000428_abnormal_craniofacial_morphol0.96232867
84MP0010155_abnormal_intestine_physiology0.95588460
85MP0001835_abnormal_antigen_presentation0.94294183
86MP0001849_ear_inflammation0.94217015
87MP0000049_abnormal_middle_ear0.93884503
88MP0001853_heart_inflammation0.93675820
89MP0000358_abnormal_cell_content/0.92872394
90MP0000465_gastrointestinal_hemorrhage0.92818186
91MP0002420_abnormal_adaptive_immunity0.91768531
92MP0005501_abnormal_skin_physiology0.91163471
93MP0005375_adipose_tissue_phenotype0.91052406
94MP0001915_intracranial_hemorrhage0.90860045
95MP0002405_respiratory_system_inflammati0.90387211
96MP0001819_abnormal_immune_cell0.89889943
97MP0003436_decreased_susceptibility_to0.88135760
98MP0002452_abnormal_antigen_presenting0.87393651
99MP0002009_preneoplasia0.86753304
100MP0001881_abnormal_mammary_gland0.86489087
101MP0003119_abnormal_digestive_system0.84879819
102MP0003300_gastrointestinal_ulcer0.84617916
103MP0003453_abnormal_keratinocyte_physiol0.83804673
104MP0001873_stomach_inflammation0.81688083
105MP0000733_abnormal_muscle_development0.81170713
106MP0000003_abnormal_adipose_tissue0.79996502
107MP0003866_abnormal_defecation0.79527299
108MP0002114_abnormal_axial_skeleton0.79394489
109MP0002089_abnormal_postnatal_growth/wei0.78828636
110MP0002723_abnormal_immune_serum0.78509501
111MP0002877_abnormal_melanocyte_morpholog0.78061741
112MP0002006_tumorigenesis0.78001870
113MP0009672_abnormal_birth_weight0.76486442
114MP0000762_abnormal_tongue_morphology0.76410442
115MP0002098_abnormal_vibrissa_morphology0.75802385
116MP0000566_synostosis0.74846662
117MP0000750_abnormal_muscle_regeneration0.73787712
118MP0002111_abnormal_tail_morphology0.73777568
119MP0008877_abnormal_DNA_methylation0.73409735
120MP0005621_abnormal_cell_physiology0.72332009
121MP0005384_cellular_phenotype0.72300408
122MP0009250_abnormal_appendicular_skeleto0.72240245
123MP0005464_abnormal_platelet_physiology0.71617188
124MP0005025_abnormal_response_to0.71438486
125MP0001188_hyperpigmentation0.70573123
126MP0008770_decreased_survivor_rate0.70482168
127MP0009931_abnormal_skin_appearance0.68833288
128MP0005671_abnormal_response_to0.68419236
129MP0003186_abnormal_redox_activity0.67991421
130MP0003121_genomic_imprinting0.67952221
131MP0001727_abnormal_embryo_implantation0.67819640
132MP0004947_skin_inflammation0.67501210
133MP0010630_abnormal_cardiac_muscle0.67153076
134MP0001340_abnormal_eyelid_morphology0.65650620
135MP0002653_abnormal_ependyma_morphology0.64830483
136MP0002092_abnormal_eye_morphology0.64589634
137MP0002132_abnormal_respiratory_system0.63347835
138MP0002210_abnormal_sex_determination0.62794380
139MP0001145_abnormal_male_reproductive0.61190171
140MP0005000_abnormal_immune_tolerance0.60989456

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.84477950
2Abnormal number of erythroid precursors (HP:0012131)5.42238312
3Reticulocytopenia (HP:0001896)5.36188063
4Colon cancer (HP:0003003)4.00028904
5Thrombocytosis (HP:0001894)3.71177349
6Pallor (HP:0000980)3.62031976
7Macrocytic anemia (HP:0001972)3.57235263
8Oral leukoplakia (HP:0002745)3.49100053
9Aplastic anemia (HP:0001915)3.41145062
10Selective tooth agenesis (HP:0001592)3.31677378
11Birth length less than 3rd percentile (HP:0003561)3.18521363
12Broad distal phalanx of finger (HP:0009836)3.12147602
13Ependymoma (HP:0002888)2.99450482
14Hyperthyroidism (HP:0000836)2.95958591
15Microretrognathia (HP:0000308)2.91993814
16Basal cell carcinoma (HP:0002671)2.88789951
17Microvesicular hepatic steatosis (HP:0001414)2.86715913
18Truncus arteriosus (HP:0001660)2.76379804
1911 pairs of ribs (HP:0000878)2.75161467
20Medulloblastoma (HP:0002885)2.73033690
21Abnormality of reticulocytes (HP:0004312)2.68197551
22Ragged-red muscle fibers (HP:0003200)2.66713188
23Trismus (HP:0000211)2.66233745
24Multiple enchondromatosis (HP:0005701)2.65632915
25Spinal cord lesions (HP:0100561)2.61336905
26Syringomyelia (HP:0003396)2.61336905
27Absent thumb (HP:0009777)2.60691422
28Abnormality of the anterior horn cell (HP:0006802)2.60335868
29Degeneration of anterior horn cells (HP:0002398)2.60335868
30Thoracic kyphosis (HP:0002942)2.58095796
31Neoplasm of the pancreas (HP:0002894)2.54644723
32Abnormality of the phalanges of the hallux (HP:0010057)2.50967358
33Deep palmar crease (HP:0006191)2.48757091
34Abnormality of the thoracic spine (HP:0100711)2.48452737
35Missing ribs (HP:0000921)2.47177210
36IgM deficiency (HP:0002850)2.37025652
37Partial duplication of thumb phalanx (HP:0009944)2.36101931
38Agnosia (HP:0010524)2.34954988
39Rough bone trabeculation (HP:0100670)2.34650976
40Breast hypoplasia (HP:0003187)2.33813183
41Myelodysplasia (HP:0002863)2.33410601
42Hypertensive crisis (HP:0100735)2.30153678
43Seborrheic dermatitis (HP:0001051)2.26615726
44Aplasia/Hypoplasia of the sacrum (HP:0008517)2.25604774
45Amaurosis fugax (HP:0100576)2.19733252
46Partial duplication of the phalanx of hand (HP:0009999)2.19140141
47Insomnia (HP:0100785)2.19056212
48Proximal placement of thumb (HP:0009623)2.18246573
49Rectal prolapse (HP:0002035)2.18081933
50Abnormal number of incisors (HP:0011064)2.17940949
51Septate vagina (HP:0001153)2.16832888
52Self-mutilation (HP:0000742)2.16617675
53Duplication of thumb phalanx (HP:0009942)2.16133212
54High anterior hairline (HP:0009890)2.14294166
55Deviation of the thumb (HP:0009603)2.13483390
56Patellar aplasia (HP:0006443)2.12149382
57Premature skin wrinkling (HP:0100678)2.11155905
58Adenoma sebaceum (HP:0009720)2.11111334
59Angiofibromas (HP:0010615)2.11111334
60Rhabdomyosarcoma (HP:0002859)2.10458775
61Progressive external ophthalmoplegia (HP:0000590)2.10412889
62Long palpebral fissure (HP:0000637)2.10397456
63Abnormality of the distal phalanx of the thumb (HP:0009617)2.10380517
64Poikiloderma (HP:0001029)2.08969992
65Spastic diplegia (HP:0001264)2.08410404
66Hyperacusis (HP:0010780)2.08368793
67Squamous cell carcinoma (HP:0002860)2.05600228
68Disproportionate tall stature (HP:0001519)2.05390531
69Achilles tendon contracture (HP:0001771)2.04947113
70Ulnar bowing (HP:0003031)2.03801824
71Abnormality of the columella (HP:0009929)2.02297439
72High pitched voice (HP:0001620)2.02260493
73Patellar dislocation (HP:0002999)2.01545029
74Abnormality of the umbilical cord (HP:0010881)2.00208751
75Atresia of the external auditory canal (HP:0000413)1.99809983
76Aplasia/Hypoplasia of the patella (HP:0006498)1.98387313
77Aplasia/Hypoplasia of the thymus (HP:0010515)1.97409126
78Carpal bone hypoplasia (HP:0001498)1.97244637
79Lymphoma (HP:0002665)1.96698342
80Short middle phalanx of the 5th finger (HP:0004220)1.96532453
81Hypoparathyroidism (HP:0000829)1.96168383
82Increased density of long bones (HP:0006392)1.96088215
83Abnormal umbilical cord blood vessels (HP:0011403)1.94876110
84Single umbilical artery (HP:0001195)1.94876110
85Abnormality of the fetal cardiovascular system (HP:0010948)1.94876110
86Increased nuchal translucency (HP:0010880)1.92321761
87Flat acetabular roof (HP:0003180)1.92235389
88Elevated erythrocyte sedimentation rate (HP:0003565)1.90848759
89Abnormality of the calcaneus (HP:0008364)1.90567052
90Premature graying of hair (HP:0002216)1.90468520
91Asplenia (HP:0001746)1.89538091
92Slender long bone (HP:0003100)1.89490420
93Overlapping toe (HP:0001845)1.89252452
94Facial hemangioma (HP:0000329)1.88690648
95Biliary tract neoplasm (HP:0100574)1.88388075
96Cellular immunodeficiency (HP:0005374)1.88107915
97Abnormality of the distal phalanges of the toes (HP:0010182)1.87908877
98Chronic otitis media (HP:0000389)1.87746486
99Abnormality of T cell physiology (HP:0011840)1.86792373
100Tracheoesophageal fistula (HP:0002575)1.86706027
101Abnormality of T cells (HP:0002843)1.83999467
102Chromsome breakage (HP:0040012)1.83629356
103Testicular atrophy (HP:0000029)1.83057627
104Abnormality of chromosome stability (HP:0003220)1.82828125
105Prominent nose (HP:0000448)1.82679721
106Aplasia/Hypoplasia of the spleen (HP:0010451)1.82120966
107Abnormality of the preputium (HP:0100587)1.82051711
108Abnormality of the parietal bone (HP:0002696)1.81350580
109Abnormality of the tricuspid valve (HP:0001702)1.81022894
110Neoplasm of the colon (HP:0100273)1.80772578
111Petechiae (HP:0000967)1.80066021
112Glossoptosis (HP:0000162)1.79951840
113Bicuspid aortic valve (HP:0001647)1.78497172
114Meckel diverticulum (HP:0002245)1.76697509
115Hypoplasia of the radius (HP:0002984)1.76689779
116Astrocytoma (HP:0009592)1.76295372
117Abnormality of the astrocytes (HP:0100707)1.76295372
118Myopathic facies (HP:0002058)1.76063343
119Cutaneous melanoma (HP:0012056)1.75646427
120Bone marrow hypocellularity (HP:0005528)1.74833429
121Overriding aorta (HP:0002623)1.72531284
122Acute lymphatic leukemia (HP:0006721)1.72317211
123Asymmetry of the thorax (HP:0001555)1.72066513
124Elfin facies (HP:0004428)1.71997514
125Bowel incontinence (HP:0002607)1.70714775
126Duodenal stenosis (HP:0100867)1.70672378
127Small intestinal stenosis (HP:0012848)1.70672378
128Premature ovarian failure (HP:0008209)1.69734354
129Transposition of the great arteries (HP:0001669)1.69608634
130Abnormal connection of the cardiac segments (HP:0011545)1.69608634
131Abnormal ventriculo-arterial connection (HP:0011563)1.69608634
132Pointed chin (HP:0000307)1.69563734
133Pancytopenia (HP:0001876)1.69518760
134Pseudobulbar signs (HP:0002200)1.69384123
135Unilateral renal agenesis (HP:0000122)1.68457962
136Preauricular skin tag (HP:0000384)1.68343783
137Protrusio acetabuli (HP:0003179)1.68123644
138Skin tags (HP:0010609)1.67847003
139Abnormal large intestine physiology (HP:0012700)1.67571730
140Abnormality of the ileum (HP:0001549)1.67433588
141Dysmetric saccades (HP:0000641)1.67313344
142Thick lower lip vermilion (HP:0000179)1.66326918
143Cleft eyelid (HP:0000625)1.66147905
144Neoplasm of striated muscle (HP:0009728)1.65139953
145Renal duplication (HP:0000075)1.64695597
146Triphalangeal thumb (HP:0001199)1.64466580
147Abnormality of the Achilles tendon (HP:0005109)1.64332475
148Intestinal polyp (HP:0005266)1.63858595
149Abnormality of the fingertips (HP:0001211)1.63806898
150Diastasis recti (HP:0001540)1.62755443
151Recurrent bronchitis (HP:0002837)1.61726224
152Cellulitis (HP:0100658)1.61040709
153Short 4th metacarpal (HP:0010044)1.60725083
154Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.60725083
155Gastrointestinal carcinoma (HP:0002672)1.60590383
156Malignant gastrointestinal tract tumors (HP:0006749)1.60590383
157Nasal polyposis (HP:0100582)1.60138305
158Abnormality of DNA repair (HP:0003254)1.59970873
159Neoplasm of the rectum (HP:0100743)1.59732635
160Chromosomal breakage induced by crosslinking agents (HP:0003221)1.58817715
161Recurrent viral infections (HP:0004429)1.58156250
162Cafe-au-lait spot (HP:0000957)1.57918824
163Progressive muscle weakness (HP:0003323)1.57789917
164Abnormal trabecular bone morphology (HP:0100671)1.56402840

Predicted kinase interactions (KEA)

RankGene SetZ-score
1SMG14.51732720
2EEF2K4.18411023
3BUB13.26078530
4CDC73.12549810
5NME23.02611441
6WEE12.99744407
7PKN22.86308421
8MAP3K102.55573625
9NEK22.53050223
10ICK2.45831599
11IRAK32.44272480
12RPS6KB22.34328567
13PRPF4B2.33856806
14VRK22.19312951
15TRIB32.17292755
16PASK2.15781998
17MAP4K12.14713959
18SCYL22.06238899
19TESK21.94971336
20TSSK61.93221997
21TGFBR11.90262356
22RPS6KA41.89688188
23FLT31.85847979
24SIK11.83728101
25EIF2AK11.76778039
26ACVR1B1.72210309
27LRRK21.71014776
28CDK121.65666669
29NEK11.54025890
30MAP3K81.48731025
31CDK41.47008618
32CDK71.46623561
33STK101.45225546
34TTK1.44492498
35PAK41.43495615
36TLK11.42007537
37DYRK31.40441950
38TAF11.38565942
39EPHA21.36948120
40KDR1.35623848
41AURKB1.35255627
42MAP2K31.31871259
43SRPK11.28016654
44ATR1.25778005
45BRAF1.24855040
46PIM21.24669183
47PLK11.19540590
48MAPKAPK31.13825567
49VRK11.09842075
50ARAF1.08279681
51MAP3K111.06560337
52RPS6KC11.05904601
53RPS6KL11.05904601
54PIM11.03935865
55BRSK21.03211652
56ZAP701.01374063
57PBK0.97417257
58MKNK10.95893550
59ALK0.94108944
60BTK0.93597901
61GRK60.92938747
62EIF2AK30.89052657
63RPS6KA60.88476315
64CHEK10.88256989
65STK40.87612243
66AURKA0.86317138
67MAP3K130.85562047
68JAK30.84838155
69TESK10.84831996
70IRAK40.84697363
71STK160.81888123
72IRAK20.81757644
73ILK0.79348415
74CDK60.76237145
75ERN10.75475097
76CHEK20.72457732
77PTK60.68501271
78HIPK20.66439212
79PAK20.65985137
80BRD40.64161293
81CDK20.61709426
82BLK0.61530698
83TTN0.60864888
84MTOR0.60383233
85BCKDK0.59628754
86CSNK2A20.58846029
87TYK20.58230013
88PRKD30.57819802
89PAK10.57068379
90RPS6KA20.56776765
91CSF1R0.55793797
92ATM0.55211266
93KIT0.54827940
94AKT20.54269911
95RPS6KA50.52789317
96MAP3K30.52677679
97BRSK10.52319872
98CDK90.50948774
99DAPK30.49852167
100MAP2K20.48694559
101DAPK10.47667933
102MAP3K10.45262357
103CDK80.45166365
104KSR20.44689345
105PRKD20.44551331
106CLK10.44485727
107PDPK10.44242501
108CDK190.44069002
109TEC0.44048539
110PLK40.43090026
111PLK30.42566593
112MAPK110.42113129
113CSNK2A10.41926984
114MKNK20.41883243
115TBK10.39034127
116ABL20.38917143
117PRKCI0.34912778
118FGFR10.34535727
119CDK11A0.34214404
120RPS6KA10.33147639
121CDK10.31586216
122TAOK10.31548450
123RPS6KB10.30805070
124RAF10.30426570
125MAPKAPK20.30036991
126LCK0.29986537
127AKT10.29839004
128FGFR40.28114550
129IKBKB0.28066668
130TAOK20.27643941
131TYRO30.27352040

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.96244104
2* Ribosome_Homo sapiens_hsa030104.52898127
3Mismatch repair_Homo sapiens_hsa034303.87139268
4Spliceosome_Homo sapiens_hsa030403.21511451
5Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.01126697
6Base excision repair_Homo sapiens_hsa034102.91647513
7One carbon pool by folate_Homo sapiens_hsa006702.82434193
8RNA transport_Homo sapiens_hsa030132.77455814
9Nucleotide excision repair_Homo sapiens_hsa034202.55051008
10Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.52593005
11Proteasome_Homo sapiens_hsa030502.45919303
12Cell cycle_Homo sapiens_hsa041102.34748486
13Homologous recombination_Homo sapiens_hsa034402.34044159
14RNA polymerase_Homo sapiens_hsa030202.31391698
15Pyrimidine metabolism_Homo sapiens_hsa002402.18529717
16RNA degradation_Homo sapiens_hsa030181.60484860
17Non-homologous end-joining_Homo sapiens_hsa034501.55459406
18p53 signaling pathway_Homo sapiens_hsa041151.54382593
19mRNA surveillance pathway_Homo sapiens_hsa030151.54037002
20Systemic lupus erythematosus_Homo sapiens_hsa053221.46076273
21Fanconi anemia pathway_Homo sapiens_hsa034601.42029914
22Antigen processing and presentation_Homo sapiens_hsa046121.22479118
23Sulfur relay system_Homo sapiens_hsa041221.19926789
24Viral carcinogenesis_Homo sapiens_hsa052031.17230818
25Herpes simplex infection_Homo sapiens_hsa051681.12398170
26Epstein-Barr virus infection_Homo sapiens_hsa051691.11197691
27Basal transcription factors_Homo sapiens_hsa030221.06173838
28Pentose phosphate pathway_Homo sapiens_hsa000301.04668596
29Biosynthesis of amino acids_Homo sapiens_hsa012301.04549558
30Primary immunodeficiency_Homo sapiens_hsa053401.04440785
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.99753063
32HTLV-I infection_Homo sapiens_hsa051660.99449882
33Cyanoamino acid metabolism_Homo sapiens_hsa004600.99396019
34Selenocompound metabolism_Homo sapiens_hsa004500.95946347
35Fructose and mannose metabolism_Homo sapiens_hsa000510.94900921
36Thyroid cancer_Homo sapiens_hsa052160.94013685
37Purine metabolism_Homo sapiens_hsa002300.92969870
38Small cell lung cancer_Homo sapiens_hsa052220.90998458
39Legionellosis_Homo sapiens_hsa051340.88660303
40Cysteine and methionine metabolism_Homo sapiens_hsa002700.88092461
41Endometrial cancer_Homo sapiens_hsa052130.87807688
42Chronic myeloid leukemia_Homo sapiens_hsa052200.87733490
43Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81438867
44Folate biosynthesis_Homo sapiens_hsa007900.79092821
45Drug metabolism - other enzymes_Homo sapiens_hsa009830.78194627
46Acute myeloid leukemia_Homo sapiens_hsa052210.76439632
47Longevity regulating pathway - mammal_Homo sapiens_hsa042110.76113395
48Apoptosis_Homo sapiens_hsa042100.75574009
49Bladder cancer_Homo sapiens_hsa052190.74913868
50Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73079203
51Shigellosis_Homo sapiens_hsa051310.71989567
52Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.70639117
53Transcriptional misregulation in cancer_Homo sapiens_hsa052020.70571941
54Vitamin B6 metabolism_Homo sapiens_hsa007500.70125012
55MicroRNAs in cancer_Homo sapiens_hsa052060.70020044
56Prostate cancer_Homo sapiens_hsa052150.68532564
57Measles_Homo sapiens_hsa051620.67590489
58Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.66132047
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.65886100
60Glioma_Homo sapiens_hsa052140.64771142
61Notch signaling pathway_Homo sapiens_hsa043300.62349888
62Thyroid hormone signaling pathway_Homo sapiens_hsa049190.60861464
63Melanoma_Homo sapiens_hsa052180.60369073
64N-Glycan biosynthesis_Homo sapiens_hsa005100.59821457
65Hepatitis B_Homo sapiens_hsa051610.59820601
66Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.59593669
67Carbon metabolism_Homo sapiens_hsa012000.59243203
68Colorectal cancer_Homo sapiens_hsa052100.59030444
69ErbB signaling pathway_Homo sapiens_hsa040120.58073997
70Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.57448404
71Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56696743
72NF-kappa B signaling pathway_Homo sapiens_hsa040640.56159609
73Lysine degradation_Homo sapiens_hsa003100.54530867
74Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.53999719
75Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.53377233
76Insulin signaling pathway_Homo sapiens_hsa049100.52074610
77Renal cell carcinoma_Homo sapiens_hsa052110.51285625
78Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51033627
79Alcoholism_Homo sapiens_hsa050340.50861050
80Hematopoietic cell lineage_Homo sapiens_hsa046400.50413485
81Oocyte meiosis_Homo sapiens_hsa041140.49164321
822-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.48773474
83HIF-1 signaling pathway_Homo sapiens_hsa040660.47889971
84B cell receptor signaling pathway_Homo sapiens_hsa046620.47798812
85Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47294750
86Huntingtons disease_Homo sapiens_hsa050160.47274080
87Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.47214204
88Non-small cell lung cancer_Homo sapiens_hsa052230.47064780
89Other glycan degradation_Homo sapiens_hsa005110.46682696
90Viral myocarditis_Homo sapiens_hsa054160.46434550
91Leishmaniasis_Homo sapiens_hsa051400.43984101
92Prion diseases_Homo sapiens_hsa050200.43925636
93AMPK signaling pathway_Homo sapiens_hsa041520.43601714
94Pyruvate metabolism_Homo sapiens_hsa006200.41678462
95Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.41295225
96Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.40986211
97Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.40447956
98Influenza A_Homo sapiens_hsa051640.39346987
99Basal cell carcinoma_Homo sapiens_hsa052170.39228128
100Leukocyte transendothelial migration_Homo sapiens_hsa046700.38582831
101TGF-beta signaling pathway_Homo sapiens_hsa043500.36474746
102Glutathione metabolism_Homo sapiens_hsa004800.36272092
103Hepatitis C_Homo sapiens_hsa051600.35344462
104Hippo signaling pathway_Homo sapiens_hsa043900.35261507
105Choline metabolism in cancer_Homo sapiens_hsa052310.34892680
106Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.34785578
107T cell receptor signaling pathway_Homo sapiens_hsa046600.34423264
108Toxoplasmosis_Homo sapiens_hsa051450.34185854
109Pathways in cancer_Homo sapiens_hsa052000.34158912
110RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.34040206
111Jak-STAT signaling pathway_Homo sapiens_hsa046300.33684339
112Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.32991812
113Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.32624858
114Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.32607855
115Galactose metabolism_Homo sapiens_hsa000520.32581201
116Pancreatic cancer_Homo sapiens_hsa052120.31554659
117mTOR signaling pathway_Homo sapiens_hsa041500.30826517
118AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.28147620
119NOD-like receptor signaling pathway_Homo sapiens_hsa046210.28101032
120Prolactin signaling pathway_Homo sapiens_hsa049170.28048949
121Proteoglycans in cancer_Homo sapiens_hsa052050.26310314
122Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.23939832
123VEGF signaling pathway_Homo sapiens_hsa043700.23233799
124Neurotrophin signaling pathway_Homo sapiens_hsa047220.22828085
125Protein export_Homo sapiens_hsa030600.21550910
126Platelet activation_Homo sapiens_hsa046110.19701756

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »