RPS20P10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)6.87478501
2ribosomal small subunit assembly (GO:0000028)6.68689764
3viral transcription (GO:0019083)6.67409931
4energy coupled proton transport, down electrochemical gradient (GO:0015985)6.57917364
5ATP synthesis coupled proton transport (GO:0015986)6.57917364
6mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.56142982
7translational termination (GO:0006415)6.36022111
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.80734167
9cotranslational protein targeting to membrane (GO:0006613)5.68732792
10protein targeting to ER (GO:0045047)5.64267703
11mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.60590239
12establishment of protein localization to endoplasmic reticulum (GO:0072599)5.42928013
13translational elongation (GO:0006414)5.40591063
14protein localization to endoplasmic reticulum (GO:0070972)5.39047849
15respiratory electron transport chain (GO:0022904)4.96448822
16electron transport chain (GO:0022900)4.89492602
17cellular protein complex disassembly (GO:0043624)4.74540712
18viral life cycle (GO:0019058)4.72961572
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.51125360
20translational initiation (GO:0006413)4.14592300
21protein complex biogenesis (GO:0070271)4.12859194
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.09326925
23NADH dehydrogenase complex assembly (GO:0010257)4.09326925
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.09326925
25establishment of protein localization to mitochondrial membrane (GO:0090151)4.07538716
26chaperone-mediated protein transport (GO:0072321)4.05401635
27negative regulation of heart rate (GO:0010459)4.03074109
28ribosomal large subunit biogenesis (GO:0042273)4.01041214
29protein complex disassembly (GO:0043241)3.89786697
30behavioral response to nicotine (GO:0035095)3.88557884
31ATP biosynthetic process (GO:0006754)3.84247203
32protein targeting to membrane (GO:0006612)3.81001970
33macromolecular complex disassembly (GO:0032984)3.77564010
34hydrogen ion transmembrane transport (GO:1902600)3.72246119
35translation (GO:0006412)3.67696953
36ribosomal small subunit biogenesis (GO:0042274)3.62890440
37regulation of hypersensitivity (GO:0002883)3.61275508
38RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.61261594
39tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.61261594
40mitochondrial respiratory chain complex assembly (GO:0033108)3.60147471
41positive regulation of mast cell activation involved in immune response (GO:0033008)3.59858864
42positive regulation of mast cell degranulation (GO:0043306)3.59858864
43protein neddylation (GO:0045116)3.56218772
44purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.50373225
45proton transport (GO:0015992)3.46219524
46positive regulation of inflammatory response to antigenic stimulus (GO:0002863)3.43203714
47nonmotile primary cilium assembly (GO:0035058)3.41351629
48dopamine transport (GO:0015872)3.41250425
49purine nucleoside triphosphate biosynthetic process (GO:0009145)3.40412188
50hydrogen transport (GO:0006818)3.40366677
51nuclear-transcribed mRNA catabolic process (GO:0000956)3.22805552
52regulation of cellular respiration (GO:0043457)3.21116762
53positive regulation of mast cell activation (GO:0033005)3.15372987
54regulation of acute inflammatory response to antigenic stimulus (GO:0002864)3.15295232
55DNA deamination (GO:0045006)3.13521416
56response to pheromone (GO:0019236)3.12187907
57aldehyde catabolic process (GO:0046185)3.12149514
58base-excision repair, AP site formation (GO:0006285)3.05779889
59mRNA catabolic process (GO:0006402)3.00872371
60mast cell activation (GO:0045576)2.97493017
61ribonucleoside triphosphate biosynthetic process (GO:0009201)2.89059181
62regulation of cilium movement (GO:0003352)2.87872023
63one-carbon compound transport (GO:0019755)2.87223472
64respiratory chain complex IV assembly (GO:0008535)2.86832947
65negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.84532079
66epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.77579974
67RNA catabolic process (GO:0006401)2.77386724
68platelet dense granule organization (GO:0060155)2.76561717
69pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.73473988
70monoamine transport (GO:0015844)2.72071333
71nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.71004056
72establishment of protein localization to membrane (GO:0090150)2.70845394
73left/right axis specification (GO:0070986)2.70225473
74oxidative phosphorylation (GO:0006119)2.66396664
75cytochrome complex assembly (GO:0017004)2.66001483
76deoxyribose phosphate catabolic process (GO:0046386)2.63583766
77protein prenylation (GO:0018342)2.58906353
78prenylation (GO:0097354)2.58906353
79somite development (GO:0061053)2.54146124
80exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.54019740
81positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.52865355
82kynurenine metabolic process (GO:0070189)2.52836763
83deoxyribonucleotide catabolic process (GO:0009264)2.51098926
84water-soluble vitamin biosynthetic process (GO:0042364)2.50341254
85negative regulation of response to food (GO:0032096)2.49628005
86negative regulation of appetite (GO:0032099)2.49628005
87spliceosomal complex assembly (GO:0000245)2.49108521
88protein-cofactor linkage (GO:0018065)2.47191229
89organelle disassembly (GO:1903008)2.46351334
90protein targeting (GO:0006605)2.43219848
91cellular component biogenesis (GO:0044085)2.43121861
92GTP biosynthetic process (GO:0006183)2.43105628
93viral protein processing (GO:0019082)2.42570687
94skeletal muscle tissue regeneration (GO:0043403)2.42526843
95cell proliferation in forebrain (GO:0021846)2.41708101
96nucleoside triphosphate biosynthetic process (GO:0009142)2.38729075
97indolalkylamine metabolic process (GO:0006586)2.37617512
98protein localization to cilium (GO:0061512)2.37418788
99negative regulation of mast cell activation (GO:0033004)2.35847792
100regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.35483157

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.23885822
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.17797538
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.21340534
4VDR_22108803_ChIP-Seq_LS180_Human3.05103436
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.98120460
6EST1_17652178_ChIP-ChIP_JURKAT_Human2.54511767
7ZNF274_21170338_ChIP-Seq_K562_Hela2.44009338
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.30193506
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.28189873
10IGF1R_20145208_ChIP-Seq_DFB_Human2.16327116
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.13695752
12TAF15_26573619_Chip-Seq_HEK293_Human2.11923426
13VDR_23849224_ChIP-Seq_CD4+_Human1.95101130
14FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.93170885
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.87354301
16ELK1_19687146_ChIP-ChIP_HELA_Human1.87305996
17TP53_22573176_ChIP-Seq_HFKS_Human1.84933478
18IRF1_19129219_ChIP-ChIP_H3396_Human1.84747133
19FUS_26573619_Chip-Seq_HEK293_Human1.80368305
20EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.77320640
21ETS1_20019798_ChIP-Seq_JURKAT_Human1.75515631
22GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75153635
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.70390477
24RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.65674687
25MYC_18940864_ChIP-ChIP_HL60_Human1.65377658
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.64938819
27PCGF2_27294783_Chip-Seq_ESCs_Mouse1.61128410
28P300_19829295_ChIP-Seq_ESCs_Human1.59120923
29IRF8_22096565_ChIP-ChIP_GC-B_Human1.58791799
30EWS_26573619_Chip-Seq_HEK293_Human1.56563450
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55711269
32MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.53752299
33JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.52932128
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.50576282
35CBX2_27304074_Chip-Seq_ESCs_Mouse1.50172041
36AR_20517297_ChIP-Seq_VCAP_Human1.46432811
37GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.45249611
38FOXA1_25329375_ChIP-Seq_VCAP_Human1.42901826
39FOXA1_27270436_Chip-Seq_PROSTATE_Human1.42901826
40CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.42448792
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.39890315
42CTBP2_25329375_ChIP-Seq_LNCAP_Human1.36636634
43NANOG_19829295_ChIP-Seq_ESCs_Human1.35334887
44SOX2_19829295_ChIP-Seq_ESCs_Human1.35334887
45ELF1_17652178_ChIP-ChIP_JURKAT_Human1.34331163
46POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31391749
47ER_23166858_ChIP-Seq_MCF-7_Human1.30034280
48EZH2_27304074_Chip-Seq_ESCs_Mouse1.29007584
49FOXP3_21729870_ChIP-Seq_TREG_Human1.28905194
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.28523076
51ETV2_25802403_ChIP-Seq_MESCs_Mouse1.25903243
52PCGF2_27294783_Chip-Seq_NPCs_Mouse1.25096342
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.24347526
54TAF2_19829295_ChIP-Seq_ESCs_Human1.24161468
55GATA3_21878914_ChIP-Seq_MCF-7_Human1.23918049
56RNF2_27304074_Chip-Seq_NSC_Mouse1.23659865
57FOXH1_21741376_ChIP-Seq_EPCs_Human1.22729794
58JARID2_20064375_ChIP-Seq_MESCs_Mouse1.20857608
59NCOR_22424771_ChIP-Seq_293T_Human1.20039763
60ERG_20517297_ChIP-Seq_VCAP_Human1.18923725
61CBP_20019798_ChIP-Seq_JUKART_Human1.18199239
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.18199239
63BP1_19119308_ChIP-ChIP_Hs578T_Human1.18082644
64IRF8_21731497_ChIP-ChIP_J774_Mouse1.17779618
65PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.17162115
66SRF_21415370_ChIP-Seq_HL-1_Mouse1.16262671
67MYC_19829295_ChIP-Seq_ESCs_Human1.15998228
68GBX2_23144817_ChIP-Seq_PC3_Human1.15259854
69CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.13134210
70EED_16625203_ChIP-ChIP_MESCs_Mouse1.12447403
71UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.10987639
72GATA3_26560356_Chip-Seq_TH2_Human1.09940194
73EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.07556933
74ELK1_22589737_ChIP-Seq_MCF10A_Human1.07059564
75TCF4_22108803_ChIP-Seq_LS180_Human1.06129413
76MYC_18555785_ChIP-Seq_MESCs_Mouse1.05441426
77PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.05079300
78AUTS2_25519132_ChIP-Seq_293T-REX_Human1.04687199
79CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.04280790
80TDRD3_21172665_ChIP-Seq_MCF-7_Human1.03282486
81FOXA1_21572438_ChIP-Seq_LNCaP_Human1.02966221
82EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.02360404
83ERA_21632823_ChIP-Seq_H3396_Human1.02302084
84TTF2_22483619_ChIP-Seq_HELA_Human1.01264851
85SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01080625
86EZH2_27294783_Chip-Seq_ESCs_Mouse1.00955999
87NANOG_20526341_ChIP-Seq_ESCs_Human0.98104657
88BCAT_22108803_ChIP-Seq_LS180_Human0.94453835
89NFE2_27457419_Chip-Seq_LIVER_Mouse0.94203847
90TAL1_26923725_Chip-Seq_HPCs_Mouse0.93644315
91SUZ12_27294783_Chip-Seq_ESCs_Mouse0.93603333
92FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.93427937
93P53_21459846_ChIP-Seq_SAOS-2_Human0.92159887
94KLF5_20875108_ChIP-Seq_MESCs_Mouse0.92138500
95RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91957963
96POU5F1_16153702_ChIP-ChIP_HESCs_Human0.91033634
97IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.89922239
98CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.86624699
99TOP2B_26459242_ChIP-Seq_MCF-7_Human0.86062168
100SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.85932929

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.49522541
2MP0001835_abnormal_antigen_presentation3.50693039
3MP0006292_abnormal_olfactory_placode3.12240291
4MP0006072_abnormal_retinal_apoptosis2.56280814
5MP0001529_abnormal_vocalization2.35569828
6MP0005671_abnormal_response_to2.35436376
7MP0002837_dystrophic_cardiac_calcinosis2.34588371
8MP0003646_muscle_fatigue2.26116844
9MP0003195_calcinosis2.23736679
10MP0005646_abnormal_pituitary_gland2.20855304
11MP0004142_abnormal_muscle_tone2.12898910
12MP0008877_abnormal_DNA_methylation1.99755798
13MP0003787_abnormal_imprinting1.92727167
14MP0002163_abnormal_gland_morphology1.90987292
15MP0008789_abnormal_olfactory_epithelium1.90498705
16MP0002102_abnormal_ear_morphology1.88255043
17MP0006276_abnormal_autonomic_nervous1.80102902
18MP0005367_renal/urinary_system_phenotyp1.79980719
19MP0000516_abnormal_urinary_system1.79980719
20MP0004145_abnormal_muscle_electrophysio1.76842496
21MP0008872_abnormal_physiological_respon1.74425083
22MP0005551_abnormal_eye_electrophysiolog1.61286297
23MP0001986_abnormal_taste_sensitivity1.60773510
24MP0000372_irregular_coat_pigmentation1.58658649
25MP0004147_increased_porphyrin_level1.57361804
26MP0001968_abnormal_touch/_nociception1.56749088
27MP0008875_abnormal_xenobiotic_pharmacok1.48865385
28MP0002638_abnormal_pupillary_reflex1.48805048
29MP0005253_abnormal_eye_physiology1.46398739
30MP0003880_abnormal_central_pattern1.45358021
31MP0005645_abnormal_hypothalamus_physiol1.44973096
32MP0008995_early_reproductive_senescence1.42789092
33MP0009764_decreased_sensitivity_to1.39813497
34MP0002653_abnormal_ependyma_morphology1.39384645
35MP0005075_abnormal_melanosome_morpholog1.38947425
36MP0003011_delayed_dark_adaptation1.34678857
37MP0001905_abnormal_dopamine_level1.34027763
38MP0005499_abnormal_olfactory_system1.33703946
39MP0005394_taste/olfaction_phenotype1.33703946
40MP0003806_abnormal_nucleotide_metabolis1.31418142
41MP0005379_endocrine/exocrine_gland_phen1.25829633
42MP0001970_abnormal_pain_threshold1.25420295
43MP0001800_abnormal_humoral_immune1.23939395
44MP0005423_abnormal_somatic_nervous1.18351956
45MP0002736_abnormal_nociception_after1.17728999
46MP0003252_abnormal_bile_duct1.17697424
47MP0001919_abnormal_reproductive_system1.17356977
48MP0002272_abnormal_nervous_system1.15696664
49MP0009745_abnormal_behavioral_response1.14569770
50MP0003724_increased_susceptibility_to1.13175022
51MP0005389_reproductive_system_phenotype1.13117770
52MP0004885_abnormal_endolymph1.11658669
53MP0001440_abnormal_grooming_behavior1.09951576
54MP0003121_genomic_imprinting1.05488353
55MP0002557_abnormal_social/conspecific_i1.04378826
56MP0001486_abnormal_startle_reflex1.04316752
57MP0009785_altered_susceptibility_to1.02795123
58MP0005084_abnormal_gallbladder_morpholo1.01355239
59MP0002735_abnormal_chemical_nociception0.99955508
60MP0000631_abnormal_neuroendocrine_gland0.99941679
61MP0002095_abnormal_skin_pigmentation0.98872901
62MP0002234_abnormal_pharynx_morphology0.97106089
63MP0003122_maternal_imprinting0.96820247
64MP0003186_abnormal_redox_activity0.96662991
65MP0001485_abnormal_pinna_reflex0.96579878
66MP0001984_abnormal_olfaction0.96333101
67MP0002148_abnormal_hypersensitivity_rea0.94768808
68MP0002733_abnormal_thermal_nociception0.93915480
69MP0005360_urolithiasis0.93761999
70MP0006036_abnormal_mitochondrial_physio0.93651558
71MP0005410_abnormal_fertilization0.93576490
72MP0005195_abnormal_posterior_eye0.89914788
73MP0008775_abnormal_heart_ventricle0.88465519
74MP0002452_abnormal_antigen_presenting0.87686325
75MP0002160_abnormal_reproductive_system0.87007313
76MP0002723_abnormal_immune_serum0.86741445
77MP0009046_muscle_twitch0.86472735
78MP0002822_catalepsy0.85607256
79MP0002572_abnormal_emotion/affect_behav0.85515211
80MP0010386_abnormal_urinary_bladder0.85172814
81MP0005000_abnormal_immune_tolerance0.83269384
82MP0004742_abnormal_vestibular_system0.80255343
83MP0005332_abnormal_amino_acid0.80158131
84MP0002876_abnormal_thyroid_physiology0.79012657
85MP0000049_abnormal_middle_ear0.77188893
86MP0000685_abnormal_immune_system0.76941154
87MP0001756_abnormal_urination0.74069589
88MP0003283_abnormal_digestive_organ0.73862057
89MP0005636_abnormal_mineral_homeostasis0.71563711
90MP0001765_abnormal_ion_homeostasis0.71491996
91MP0005085_abnormal_gallbladder_physiolo0.71371449
92MP0003123_paternal_imprinting0.69866249
93MP0002734_abnormal_mechanical_nocicepti0.69844283
94MP0000230_abnormal_systemic_arterial0.69172038
95MP0001819_abnormal_immune_cell0.68988630
96MP0004924_abnormal_behavior0.68644668
97MP0005386_behavior/neurological_phenoty0.68644668
98MP0002420_abnormal_adaptive_immunity0.67313591
99MP0002928_abnormal_bile_duct0.66990101
100MP0001764_abnormal_homeostasis0.66024752

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)5.54917311
2Abnormal mitochondria in muscle tissue (HP:0008316)4.83958723
3Mitochondrial inheritance (HP:0001427)4.75692482
4Progressive macrocephaly (HP:0004481)4.64618353
5Acute encephalopathy (HP:0006846)4.61162923
6Congenital, generalized hypertrichosis (HP:0004540)4.33942074
7Hepatocellular necrosis (HP:0001404)4.25443342
83-Methylglutaconic aciduria (HP:0003535)4.10466954
9Increased CSF lactate (HP:0002490)4.08916990
10Absent rod-and cone-mediated responses on ERG (HP:0007688)3.93318496
11Chronic sinusitis (HP:0011109)3.73476922
12Abnormal rod and cone electroretinograms (HP:0008323)3.71335881
13Hypothermia (HP:0002045)3.59456733
14Hepatic necrosis (HP:0002605)3.53794543
15Cerebral edema (HP:0002181)3.42048660
16Reticulocytopenia (HP:0001896)3.25979600
17Medial flaring of the eyebrow (HP:0010747)3.23381781
18Chronic otitis media (HP:0000389)3.09707727
19Abolished electroretinogram (ERG) (HP:0000550)3.07290249
20Abnormality of midbrain morphology (HP:0002418)2.99303881
21Molar tooth sign on MRI (HP:0002419)2.99303881
22Leukodystrophy (HP:0002415)2.86382446
23Optic disc pallor (HP:0000543)2.85893113
24Decreased central vision (HP:0007663)2.84528372
25Increased hepatocellular lipid droplets (HP:0006565)2.84003042
26True hermaphroditism (HP:0010459)2.82715083
27Bony spicule pigmentary retinopathy (HP:0007737)2.81802491
28Abnormality of cells of the erythroid lineage (HP:0012130)2.77965247
29Pancreatic cysts (HP:0001737)2.76543118
30Congenital primary aphakia (HP:0007707)2.74517387
31Lipid accumulation in hepatocytes (HP:0006561)2.73798703
32Gait imbalance (HP:0002141)2.72178661
33Macrocytic anemia (HP:0001972)2.71874728
34Pancreatic fibrosis (HP:0100732)2.62457536
35Congenital stationary night blindness (HP:0007642)2.60300776
36Stenosis of the external auditory canal (HP:0000402)2.53051891
37Elevated erythrocyte sedimentation rate (HP:0003565)2.45495235
38Nephrogenic diabetes insipidus (HP:0009806)2.42063028
39Exertional dyspnea (HP:0002875)2.38268721
40Renal Fanconi syndrome (HP:0001994)2.37095263
41Recurrent bronchitis (HP:0002837)2.36775572
42Respiratory failure (HP:0002878)2.32580823
43IgG deficiency (HP:0004315)2.31953043
44Attenuation of retinal blood vessels (HP:0007843)2.25935591
45Lactic acidosis (HP:0003128)2.25526397
46Nephronophthisis (HP:0000090)2.25053003
47Constricted visual fields (HP:0001133)2.22473676
48Woolly hair (HP:0002224)2.21861270
49Pallor (HP:0000980)2.19063472
50Myokymia (HP:0002411)2.18624516
51Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.15753769
52Decreased activity of mitochondrial respiratory chain (HP:0008972)2.15753769
53Increased serum lactate (HP:0002151)2.15326852
54Abnormality of alanine metabolism (HP:0010916)2.13734771
55Hyperalaninemia (HP:0003348)2.13734771
56Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.13734771
57Increased intramyocellular lipid droplets (HP:0012240)2.11585357
58Male pseudohermaphroditism (HP:0000037)2.05995542
59Lethargy (HP:0001254)2.02325452
60Type 2 muscle fiber atrophy (HP:0003554)2.01726705
61Hypoplasia of the ulna (HP:0003022)1.99677499
62Thyroid-stimulating hormone excess (HP:0002925)1.99400386
63Sclerocornea (HP:0000647)1.98930359
64Abnormal hemoglobin (HP:0011902)1.96162845
65Aplasia/Hypoplasia of the spleen (HP:0010451)1.95855772
66Abnormality of the prostate (HP:0008775)1.95463436
67Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.92378922
68Absent thumb (HP:0009777)1.92275499
69Abnormality of renal resorption (HP:0011038)1.90670600
70Abnormal respiratory motile cilium morphology (HP:0005938)1.89990446
71Abnormal respiratory epithelium morphology (HP:0012253)1.89990446
72Keratoconus (HP:0000563)1.88577772
73Increased corneal curvature (HP:0100692)1.88577772
74Myotonia (HP:0002486)1.88429357
75Stomatitis (HP:0010280)1.87427630
76Abnormal number of erythroid precursors (HP:0012131)1.87124851
77Nasal polyposis (HP:0100582)1.86235548
78Decreased electroretinogram (ERG) amplitude (HP:0000654)1.84953857
79Asplenia (HP:0001746)1.84684819
80Vaginal atresia (HP:0000148)1.84298519
81Postaxial foot polydactyly (HP:0001830)1.83785186
82Abnormality of the renal cortex (HP:0011035)1.82326669
83Abnormality of the renal medulla (HP:0100957)1.81606955
84Increased muscle lipid content (HP:0009058)1.80493252
85Aplasia/Hypoplasia of the ulna (HP:0006495)1.80317741
86Renal cortical cysts (HP:0000803)1.79539786
87Genital tract atresia (HP:0001827)1.78944978
88Dynein arm defect of respiratory motile cilia (HP:0012255)1.78904541
89Absent/shortened dynein arms (HP:0200106)1.78904541
90Exercise intolerance (HP:0003546)1.76931960
91Pendular nystagmus (HP:0012043)1.76869564
92Hypoproteinemia (HP:0003075)1.75582505
93Hyperglycinemia (HP:0002154)1.74672961
94Abnormality of the phalanges of the 5th finger (HP:0004213)1.74285594
95CNS demyelination (HP:0007305)1.74168868
96Type II lissencephaly (HP:0007260)1.73130872
97Anomalous pulmonary venous return (HP:0010772)1.71434275
98Short tibia (HP:0005736)1.70701731
99Abnormal drinking behavior (HP:0030082)1.70571325
100Polydipsia (HP:0001959)1.70571325

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TLK14.32819240
2CDK194.24369078
3BMPR23.60660066
4MAP4K23.59548739
5MAP3K123.02856751
6TXK2.68068448
7TAOK32.54724398
8MYLK2.00942062
9ADRBK21.91422862
10GRK11.81267808
11MAP3K131.78050577
12FRK1.69038095
13MUSK1.66860942
14BCKDK1.66416757
15DYRK21.57775042
16WNK41.55688044
17PINK11.51231952
18TEC1.50678942
19STK161.50569726
20ILK1.44292069
21ZAK1.40241299
22ERBB31.34375767
23OXSR11.29237342
24IKBKB1.26093531
25BTK1.22668043
26INSRR1.21829671
27DAPK31.18461064
28FLT31.17814003
29MAP4K11.15475816
30NUAK11.13319037
31CSF1R1.10374178
32CAMKK21.09594163
33ITK1.08508511
34PIK3CG1.04722965
35WNK31.04116496
36LYN1.00464982
37TIE10.99793544
38KIT0.98936507
39KDR0.97045441
40SYK0.96189397
41EPHA40.94766329
42GRK60.93713526
43PKN10.89301603
44LIMK10.83501261
45MAPK130.82904534
46BMPR1B0.79130940
47OBSCN0.79122153
48TNK20.75754892
49DAPK10.75723844
50PIK3CA0.72445454
51ARAF0.71427369
52AURKB0.68620123
53LCK0.67508400
54PRKCE0.64872178
55PRKACA0.64391426
56STK38L0.62997417
57RPS6KA50.62880887
58CDK80.61472066
59MAPKAPK50.60431407
60BLK0.59328682
61CSNK1G20.59058124
62MATK0.58179891
63CAMK10.57751735
64ADRBK10.57344442
65VRK20.56780982
66VRK10.55888470
67MAP2K20.55213832
68PRKCG0.53517521
69CCNB10.52830032
70TRIM280.52367746
71ERBB20.52257370
72PRKCQ0.51712018
73STK390.51476264
74MAPK150.51203571
75DAPK20.49099907
76PLK20.48692444
77IGF1R0.48084787
78CHUK0.46639991
79SCYL20.46610873
80CSNK2A10.46168279
81CSNK2A20.45594807
82FES0.45314777
83ROCK10.44787608
84PHKG20.44067632
85PHKG10.44067632
86GRK70.44044661
87CSNK1G30.42819025
88PRKCA0.42551085
89CAMK2A0.42481650
90ABL10.41662781
91MAP3K40.41620914
92HCK0.40633106
93PASK0.40621399
94MAP3K140.40038601
95NTRK20.39465510
96PRKG10.37980164
97EGFR0.37130884
98CAMKK10.36993955
99PRKCD0.35208257
100PIM10.33869749

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.81528535
2Ribosome_Homo sapiens_hsa030104.52054858
3Oxidative phosphorylation_Homo sapiens_hsa001904.37426925
4Parkinsons disease_Homo sapiens_hsa050123.54658092
5Allograft rejection_Homo sapiens_hsa053303.29540078
6Intestinal immune network for IgA production_Homo sapiens_hsa046723.28401631
7Autoimmune thyroid disease_Homo sapiens_hsa053203.20110542
8Graft-versus-host disease_Homo sapiens_hsa053322.95522930
9Protein export_Homo sapiens_hsa030602.60231609
10Type I diabetes mellitus_Homo sapiens_hsa049402.56289894
11Alzheimers disease_Homo sapiens_hsa050102.47670125
12Cardiac muscle contraction_Homo sapiens_hsa042602.34758890
13Huntingtons disease_Homo sapiens_hsa050162.29662799
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.19302817
15Proteasome_Homo sapiens_hsa030502.04996927
16Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.72963485
17Homologous recombination_Homo sapiens_hsa034401.62778230
18Antigen processing and presentation_Homo sapiens_hsa046121.57557927
19Rheumatoid arthritis_Homo sapiens_hsa053231.55848902
20Staphylococcus aureus infection_Homo sapiens_hsa051501.53436888
21Viral myocarditis_Homo sapiens_hsa054161.48842506
22Phototransduction_Homo sapiens_hsa047441.46897739
23Linoleic acid metabolism_Homo sapiens_hsa005911.44673739
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.43181449
25RNA polymerase_Homo sapiens_hsa030201.38933494
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.23137958
27Collecting duct acid secretion_Homo sapiens_hsa049661.07625527
28Caffeine metabolism_Homo sapiens_hsa002321.03466421
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.02656288
30Olfactory transduction_Homo sapiens_hsa047400.97962235
31Leishmaniasis_Homo sapiens_hsa051400.95506961
32Systemic lupus erythematosus_Homo sapiens_hsa053220.95322086
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.94842783
34Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.94215421
35RNA degradation_Homo sapiens_hsa030180.89587608
36Primary immunodeficiency_Homo sapiens_hsa053400.85504213
37Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83693221
38Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79244383
39Regulation of autophagy_Homo sapiens_hsa041400.75877965
40Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74042240
41Basal transcription factors_Homo sapiens_hsa030220.73557538
42Arachidonic acid metabolism_Homo sapiens_hsa005900.72686878
43Hematopoietic cell lineage_Homo sapiens_hsa046400.71894991
44Chemical carcinogenesis_Homo sapiens_hsa052040.71683918
45Nicotine addiction_Homo sapiens_hsa050330.67355398
46Tryptophan metabolism_Homo sapiens_hsa003800.66867956
47One carbon pool by folate_Homo sapiens_hsa006700.66252997
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65584205
49Fanconi anemia pathway_Homo sapiens_hsa034600.63429421
50Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.61195073
51Morphine addiction_Homo sapiens_hsa050320.60329727
52Retinol metabolism_Homo sapiens_hsa008300.60032230
53Steroid hormone biosynthesis_Homo sapiens_hsa001400.59384457
54Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.58838108
55Maturity onset diabetes of the young_Homo sapiens_hsa049500.58171675
56Salivary secretion_Homo sapiens_hsa049700.57614674
57Nitrogen metabolism_Homo sapiens_hsa009100.57482745
58Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.56109695
59Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.55350670
60Mismatch repair_Homo sapiens_hsa034300.54415151
61Pyrimidine metabolism_Homo sapiens_hsa002400.53936587
62Propanoate metabolism_Homo sapiens_hsa006400.53811384
63Taste transduction_Homo sapiens_hsa047420.52151639
64Nucleotide excision repair_Homo sapiens_hsa034200.51829202
65Peroxisome_Homo sapiens_hsa041460.49966254
66Drug metabolism - other enzymes_Homo sapiens_hsa009830.48052223
67Sulfur relay system_Homo sapiens_hsa041220.47822329
68GABAergic synapse_Homo sapiens_hsa047270.47259730
69Ether lipid metabolism_Homo sapiens_hsa005650.46309537
70Purine metabolism_Homo sapiens_hsa002300.44091227
71Spliceosome_Homo sapiens_hsa030400.43947603
72Fat digestion and absorption_Homo sapiens_hsa049750.43239271
73Metabolic pathways_Homo sapiens_hsa011000.42137899
74Phagosome_Homo sapiens_hsa041450.41173074
75Primary bile acid biosynthesis_Homo sapiens_hsa001200.40175603
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.38385835
77Sulfur metabolism_Homo sapiens_hsa009200.37370975
78beta-Alanine metabolism_Homo sapiens_hsa004100.32577213
79Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32471960
80Cysteine and methionine metabolism_Homo sapiens_hsa002700.32080827
81Circadian entrainment_Homo sapiens_hsa047130.30138134
82Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.28698224
83Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28510181
84Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.28139629
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.28097129
86Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.27467425
87Base excision repair_Homo sapiens_hsa034100.26891625
88Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.25252985
89DNA replication_Homo sapiens_hsa030300.24812128
90Serotonergic synapse_Homo sapiens_hsa047260.22084816
91Insulin secretion_Homo sapiens_hsa049110.22074773
92Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.21207585
93Fatty acid degradation_Homo sapiens_hsa000710.20886330
94Butanoate metabolism_Homo sapiens_hsa006500.19897488
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.18792713
96Starch and sucrose metabolism_Homo sapiens_hsa005000.18470456
97Tyrosine metabolism_Homo sapiens_hsa003500.18466488
98Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.17871294
99NOD-like receptor signaling pathway_Homo sapiens_hsa046210.16990700
100Toxoplasmosis_Homo sapiens_hsa051450.16605222

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