RPS20P14

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.84649766
2GDP-mannose metabolic process (GO:0019673)7.61038951
3translational termination (GO:0006415)7.43769526
4mannose metabolic process (GO:0006013)6.90867565
5ribosomal small subunit biogenesis (GO:0042274)6.85343037
6translational elongation (GO:0006414)6.60858225
7ribosomal small subunit assembly (GO:0000028)6.33052668
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.31743252
9cotranslational protein targeting to membrane (GO:0006613)6.22403765
10nucleoside transmembrane transport (GO:1901642)6.21522414
11protein targeting to ER (GO:0045047)6.18001927
12establishment of protein localization to endoplasmic reticulum (GO:0072599)5.88220165
13protein localization to endoplasmic reticulum (GO:0070972)5.75754601
14DNA deamination (GO:0045006)5.71377483
15viral life cycle (GO:0019058)5.64900614
16energy coupled proton transport, down electrochemical gradient (GO:0015985)5.60853596
17ATP synthesis coupled proton transport (GO:0015986)5.60853596
18cellular protein complex disassembly (GO:0043624)5.55981282
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.35975429
20behavioral response to nicotine (GO:0035095)5.15394066
21regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.99894102
22maturation of SSU-rRNA (GO:0030490)4.96603107
23nucleoside transport (GO:0015858)4.81512485
24interferon-gamma production (GO:0032609)4.78668768
25translational initiation (GO:0006413)4.69237380
26protein complex disassembly (GO:0043241)4.64850126
27protein targeting to membrane (GO:0006612)4.44034274
28ribosomal large subunit biogenesis (GO:0042273)4.33562001
29macromolecular complex disassembly (GO:0032984)4.29738785
30cytidine metabolic process (GO:0046087)4.26608305
31cytidine catabolic process (GO:0006216)4.26608305
32cytidine deamination (GO:0009972)4.26608305
33nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.24825542
34exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.20502167
35tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.14953703
36RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.14953703
37translation (GO:0006412)4.12776012
38nuclear-transcribed mRNA catabolic process (GO:0000956)3.97222405
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.89094276
40mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.72311600
41mRNA catabolic process (GO:0006402)3.69537835
42outer ear morphogenesis (GO:0042473)3.66829502
43response to pheromone (GO:0019236)3.56388137
44cell proliferation in forebrain (GO:0021846)3.55805919
45reproduction (GO:0000003)3.53413300
46pyrimidine ribonucleoside catabolic process (GO:0046133)3.51939314
47water-soluble vitamin biosynthetic process (GO:0042364)3.40893235
48cellular component biogenesis (GO:0044085)3.40380551
49cofactor transport (GO:0051181)3.28103714
50modified amino acid transport (GO:0072337)3.26255974
51RNA catabolic process (GO:0006401)3.25647055
52ribonucleoprotein complex biogenesis (GO:0022613)3.22793146
53ATP biosynthetic process (GO:0006754)3.18902369
54protein neddylation (GO:0045116)3.17491758
55electron transport chain (GO:0022900)3.16937395
56mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.16615346
57respiratory electron transport chain (GO:0022904)3.14017058
58endoderm formation (GO:0001706)3.13916033
59intracellular protein transmembrane import (GO:0044743)3.11855087
60short-chain fatty acid metabolic process (GO:0046459)2.96250497
61coenzyme A biosynthetic process (GO:0015937)2.94691564
62somite development (GO:0061053)2.94641956
63establishment of protein localization to membrane (GO:0090150)2.93255961
64positive regulation of icosanoid secretion (GO:0032305)2.90325533
65phenylpropanoid metabolic process (GO:0009698)2.89564076
66positive regulation of fatty acid transport (GO:2000193)2.88271410
67purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.88236655
68otic vesicle formation (GO:0030916)2.86929354
69pantothenate metabolic process (GO:0015939)2.85529057
70meiotic chromosome segregation (GO:0045132)2.84895939
71protein complex biogenesis (GO:0070271)2.83171732
72purine nucleoside triphosphate biosynthetic process (GO:0009145)2.82424953
73positive regulation of defense response to virus by host (GO:0002230)2.80036755
74regulation of mitochondrial membrane potential (GO:0051881)2.77969740
75sulfur compound transport (GO:0072348)2.76908803
76regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.75659434
77regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.75659434
78protein targeting (GO:0006605)2.74245583
79pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.73884153
80peroxisome fission (GO:0016559)2.73452377
81cellular response to estradiol stimulus (GO:0071392)2.72668845
82positive regulation of fatty acid beta-oxidation (GO:0032000)2.71209635
83pharyngeal system development (GO:0060037)2.67614327
84mitochondrial respiratory chain complex I assembly (GO:0032981)2.66386910
85NADH dehydrogenase complex assembly (GO:0010257)2.66386910
86mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.66386910
87positive regulation of T cell apoptotic process (GO:0070234)2.62779808
88hydrogen ion transmembrane transport (GO:1902600)2.62004269
89positive regulation of transcription regulatory region DNA binding (GO:2000679)2.52067911
90lateral ventricle development (GO:0021670)2.51611255
91establishment of protein localization to organelle (GO:0072594)2.51377330
92negative regulation of cAMP-mediated signaling (GO:0043951)2.49369847
93positive regulation of fatty acid oxidation (GO:0046321)2.48204488
94indolalkylamine metabolic process (GO:0006586)2.46301971
95nucleotide-sugar biosynthetic process (GO:0009226)2.46122432
96cytolysis (GO:0019835)2.42841202
97ribonucleoside triphosphate biosynthetic process (GO:0009201)2.42797402
98protein polyglutamylation (GO:0018095)2.41810052
99mitochondrial respiratory chain complex assembly (GO:0033108)2.41050115
100chaperone-mediated protein transport (GO:0072321)10.5620186

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse6.48851202
2EZH2_22144423_ChIP-Seq_EOC_Human4.26874032
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.97261642
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.55092894
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.18430113
6VDR_22108803_ChIP-Seq_LS180_Human2.57834903
7TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.55051886
8HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.32353235
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.25067536
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.13383383
11ZNF274_21170338_ChIP-Seq_K562_Hela2.09786323
12FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.08912546
13GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.00014207
14EST1_17652178_ChIP-ChIP_JURKAT_Human1.98718969
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.97578391
16NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.89263845
17EZH2_27304074_Chip-Seq_ESCs_Mouse1.88612751
18ETS1_20019798_ChIP-Seq_JURKAT_Human1.87151995
19JARID2_20064375_ChIP-Seq_MESCs_Mouse1.86318534
20IGF1R_20145208_ChIP-Seq_DFB_Human1.81778739
21RBPJ_22232070_ChIP-Seq_NCS_Mouse1.76671732
22EED_16625203_ChIP-ChIP_MESCs_Mouse1.73631295
23RNF2_27304074_Chip-Seq_NSC_Mouse1.71443937
24NOTCH1_21737748_ChIP-Seq_TLL_Human1.69876695
25YY1_21170310_ChIP-Seq_MESCs_Mouse1.67101512
26PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.64346036
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.64286969
28CBX2_27304074_Chip-Seq_ESCs_Mouse1.59852372
29JARID2_20075857_ChIP-Seq_MESCs_Mouse1.54428084
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.51879056
31SRY_22984422_ChIP-ChIP_TESTIS_Rat1.51639872
32CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.50630584
33TP53_20018659_ChIP-ChIP_R1E_Mouse1.50071309
34EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.42542296
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.35928799
36GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.34213159
37SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.32535213
38TP53_22573176_ChIP-Seq_HFKS_Human1.31180242
39NANOG_20526341_ChIP-Seq_ESCs_Human1.30810556
40MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.29847100
41JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.29524241
42ELK1_19687146_ChIP-ChIP_HELA_Human1.29314593
43GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.28016634
44IRF1_19129219_ChIP-ChIP_H3396_Human1.27756344
45IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.25895702
46SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.25770279
47RNF2_27304074_Chip-Seq_ESCs_Mouse1.25269864
48KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.25118383
49VDR_23849224_ChIP-Seq_CD4+_Human1.23863168
50RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.22851270
51CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19883811
52RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.19555078
53MYC_18940864_ChIP-ChIP_HL60_Human1.18796975
54REST_21632747_ChIP-Seq_MESCs_Mouse1.18680740
55EZH2_18974828_ChIP-Seq_MESCs_Mouse1.17036685
56RNF2_18974828_ChIP-Seq_MESCs_Mouse1.17036685
57SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.16846566
58CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14706067
59TAF2_19829295_ChIP-Seq_ESCs_Human1.13783335
60MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13288107
61NCOR_22424771_ChIP-Seq_293T_Human1.12972140
62CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12651755
63POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12055076
64NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09467525
65HTT_18923047_ChIP-ChIP_STHdh_Human1.09161796
66GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.08060703
67KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07809951
68SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.06524221
69CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.06496274
70AUTS2_25519132_ChIP-Seq_293T-REX_Human1.05245224
71EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.05220616
72BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.04374644
73CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.04084834
74GATA3_21878914_ChIP-Seq_MCF-7_Human1.02698188
75RBPJ_21746931_ChIP-Seq_IB4_Human1.02613175
76GATA6_21074721_ChIP-Seq_CACO-2_Human1.02088489
77FOXH1_21741376_ChIP-Seq_ESCs_Human1.01812059
78HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.00903404
79ETV1_20927104_ChIP-Seq_GIST48_Human1.00874656
80ERG_21242973_ChIP-ChIP_JURKAT_Human1.00307960
81SA1_27219007_Chip-Seq_Bcells_Human1.00033750
82ERG_20517297_ChIP-Seq_VCAP_Human0.99790619
83SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.99407125
84PHF8_20622853_ChIP-Seq_HELA_Human0.99307120
85SOX2_21211035_ChIP-Seq_LN229_Human0.98446427
86ETV2_25802403_ChIP-Seq_MESCs_Mouse0.97222633
87FUS_26573619_Chip-Seq_HEK293_Human0.97056011
88MYC_19829295_ChIP-Seq_ESCs_Human0.97021610
89REST_18959480_ChIP-ChIP_MESCs_Mouse0.96457673
90E2F1_20622854_ChIP-Seq_HELA_Human0.95879324
91POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95869689
92YY1_22570637_ChIP-Seq_MALME-3M_Human0.95315717
93TP63_19390658_ChIP-ChIP_HaCaT_Human0.95263235
94AR_21572438_ChIP-Seq_LNCaP_Human0.93948991
95FOXH1_21741376_ChIP-Seq_EPCs_Human0.91927005
96VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.90185411
97MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.90056003
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.89393304
99FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.88606023
100SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.87751772

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation7.67317036
2MP0002638_abnormal_pupillary_reflex4.78571688
3MP0006292_abnormal_olfactory_placode4.27624569
4MP0003646_muscle_fatigue3.58969088
5MP0006072_abnormal_retinal_apoptosis2.51237307
6MP0005671_abnormal_response_to2.42749322
7MP0002163_abnormal_gland_morphology2.07012238
8MP0008789_abnormal_olfactory_epithelium2.04071190
9MP0000049_abnormal_middle_ear1.96488739
10MP0001529_abnormal_vocalization1.84841067
11MP0001485_abnormal_pinna_reflex1.80641421
12MP0003787_abnormal_imprinting1.78460235
13MP0003011_delayed_dark_adaptation1.75028129
14MP0000372_irregular_coat_pigmentation1.69306830
15MP0005503_abnormal_tendon_morphology1.68662645
16MP0005377_hearing/vestibular/ear_phenot1.66690212
17MP0003878_abnormal_ear_physiology1.66690212
18MP0002160_abnormal_reproductive_system1.60023673
19MP0004142_abnormal_muscle_tone1.59878082
20MP0002837_dystrophic_cardiac_calcinosis1.58057860
21MP0008877_abnormal_DNA_methylation1.57434314
22MP0006276_abnormal_autonomic_nervous1.52104899
23MP0002277_abnormal_respiratory_mucosa1.49697562
24MP0003122_maternal_imprinting1.46114725
25MP0003880_abnormal_central_pattern1.42377288
26MP0000631_abnormal_neuroendocrine_gland1.39290530
27MP0005394_taste/olfaction_phenotype1.36490418
28MP0005499_abnormal_olfactory_system1.36490418
29MP0005389_reproductive_system_phenotype1.35393384
30MP0004043_abnormal_pH_regulation1.34870791
31MP0002234_abnormal_pharynx_morphology1.34177967
32MP0001293_anophthalmia1.33476953
33MP0001188_hyperpigmentation1.32416764
34MP0003136_yellow_coat_color1.31544809
35MP0005551_abnormal_eye_electrophysiolog1.31416854
36MP0001905_abnormal_dopamine_level1.29093962
37MP0002876_abnormal_thyroid_physiology1.27188705
38MP0002102_abnormal_ear_morphology1.26640687
39MP0005253_abnormal_eye_physiology1.25664287
40MP0004133_heterotaxia1.24140053
41MP0005379_endocrine/exocrine_gland_phen1.23798793
42MP0004145_abnormal_muscle_electrophysio1.23022105
43MP0001727_abnormal_embryo_implantation1.21651540
44MP0004885_abnormal_endolymph1.19949293
45MP0001873_stomach_inflammation1.19570458
46MP0005174_abnormal_tail_pigmentation1.19318949
47MP0000778_abnormal_nervous_system1.18202508
48MP0002095_abnormal_skin_pigmentation1.15533130
49MP0004742_abnormal_vestibular_system1.15516964
50MP0001968_abnormal_touch/_nociception1.15021955
51MP0005195_abnormal_posterior_eye1.13462222
52MP0000678_abnormal_parathyroid_gland1.10440295
53MP0002249_abnormal_larynx_morphology1.10002813
54MP0005387_immune_system_phenotype1.07315762
55MP0001790_abnormal_immune_system1.07315762
56MP0002272_abnormal_nervous_system1.06879183
57MP0003938_abnormal_ear_development1.05756429
58MP0003879_abnormal_hair_cell1.05675605
59MP0005645_abnormal_hypothalamus_physiol1.05596095
60MP0002938_white_spotting1.00449654
61MP0001986_abnormal_taste_sensitivity0.99983844
62MP0008872_abnormal_physiological_respon0.97883040
63MP0009250_abnormal_appendicular_skeleto0.97108225
64MP0009333_abnormal_splenocyte_physiolog0.95615107
65MP0001542_abnormal_bone_strength0.93691761
66MP0005423_abnormal_somatic_nervous0.93349871
67MP0000026_abnormal_inner_ear0.92077280
68MP0006082_CNS_inflammation0.91886818
69MP0003195_calcinosis0.91808868
70MP0005646_abnormal_pituitary_gland0.90868272
71MP0005409_darkened_coat_color0.89828094
72MP0002752_abnormal_somatic_nervous0.87583871
73MP0009745_abnormal_behavioral_response0.87172103
74MP0001970_abnormal_pain_threshold0.87138764
75MP0002733_abnormal_thermal_nociception0.84598894
76MP0002734_abnormal_mechanical_nocicepti0.84550708
77MP0003890_abnormal_embryonic-extraembry0.82929218
78MP0002184_abnormal_innervation0.82108303
79MP0001963_abnormal_hearing_physiology0.80904035
80MP0002557_abnormal_social/conspecific_i0.80757757
81MP0002572_abnormal_emotion/affect_behav0.79621643
82MP0003121_genomic_imprinting0.79533649
83MP0003567_abnormal_fetal_cardiomyocyte0.79336302
84MP0003283_abnormal_digestive_organ0.79228833
85MP0001919_abnormal_reproductive_system0.78276027
86MP0001502_abnormal_circadian_rhythm0.76519585
87MP0002736_abnormal_nociception_after0.76144449
88MP0002138_abnormal_hepatobiliary_system0.72844774
89MP0009764_decreased_sensitivity_to0.71444102
90MP0002063_abnormal_learning/memory/cond0.71406417
91MP0002210_abnormal_sex_determination0.69856990
92MP0000955_abnormal_spinal_cord0.67934914
93MP0003137_abnormal_impulse_conducting0.66551543
94MP0002177_abnormal_outer_ear0.66141175
95MP0002735_abnormal_chemical_nociception0.65112220
96MP0005386_behavior/neurological_phenoty0.64981526
97MP0004924_abnormal_behavior0.64981526
98MP0002822_catalepsy0.64764210
99MP0001663_abnormal_digestive_system0.63751851
100MP0003936_abnormal_reproductive_system0.62353071

Predicted human phenotypes

RankGene SetZ-score
1Global brain atrophy (HP:0002283)5.99212523
2Abnormality of cells of the erythroid lineage (HP:0012130)4.50950748
3Methylmalonic acidemia (HP:0002912)4.32899054
4Hyperglycinemia (HP:0002154)4.02110092
5Hypobetalipoproteinemia (HP:0003563)3.93841891
6Dyskinesia (HP:0100660)3.86356311
7Macrocytic anemia (HP:0001972)3.80355342
8Patent foramen ovale (HP:0001655)3.77593272
9Reticulocytopenia (HP:0001896)3.68392697
10Stenosis of the external auditory canal (HP:0000402)3.56222416
11Agitation (HP:0000713)3.50173848
12Abnormality of the phalanges of the 2nd finger (HP:0009541)3.41547833
13Methylmalonic aciduria (HP:0012120)3.36313090
14Partial duplication of the phalanx of hand (HP:0009999)3.34328984
15Neurodegeneration (HP:0002180)3.29107509
16Acanthocytosis (HP:0001927)3.26623451
17Congenital stationary night blindness (HP:0007642)3.25650098
18Akinesia (HP:0002304)3.17672720
19Pallor (HP:0000980)3.03054387
20Lipid accumulation in hepatocytes (HP:0006561)3.02558289
21Abnormal number of erythroid precursors (HP:0012131)2.96195195
22Mitochondrial inheritance (HP:0001427)2.91500813
23Microretrognathia (HP:0000308)2.88764052
24Molar tooth sign on MRI (HP:0002419)2.88082184
25Abnormality of midbrain morphology (HP:0002418)2.88082184
26Restlessness (HP:0000711)2.80365138
27Increased hepatocellular lipid droplets (HP:0006565)2.78719429
28Broad distal phalanx of finger (HP:0009836)2.77012881
29Decreased muscle mass (HP:0003199)2.62970471
30Increased CSF lactate (HP:0002490)2.61112352
31Septo-optic dysplasia (HP:0100842)2.61071600
32Elevated erythrocyte sedimentation rate (HP:0003565)2.60730494
33Hyperalaninemia (HP:0003348)2.58462216
34Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.58462216
35Abnormality of alanine metabolism (HP:0010916)2.58462216
36Acute necrotizing encephalopathy (HP:0006965)2.57440005
37Hepatocellular necrosis (HP:0001404)2.53812489
38Absent rod-and cone-mediated responses on ERG (HP:0007688)2.48715525
39Abnormality of the vitamin B12 metabolism (HP:0004341)2.48280343
40Abnormality of the parietal bone (HP:0002696)2.40435723
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.39975872
42Renal Fanconi syndrome (HP:0001994)2.39325482
43Amblyopia (HP:0000646)2.35561454
44Abnormality of vitamin B metabolism (HP:0004340)2.31937629
45Abnormal mitochondria in muscle tissue (HP:0008316)2.26017032
46Dysphonia (HP:0001618)2.23228983
47Large eyes (HP:0001090)2.22379658
48Hepatic necrosis (HP:0002605)2.22279841
49Acute encephalopathy (HP:0006846)2.21296706
50Absent thumb (HP:0009777)2.21058494
51Delayed CNS myelination (HP:0002188)2.20603798
52Hemiplegia (HP:0002301)2.19077368
53Morphological abnormality of the pyramidal tract (HP:0002062)2.15605345
54Abnormal rod and cone electroretinograms (HP:0008323)2.11089515
55Congenital, generalized hypertrichosis (HP:0004540)2.10441904
56Abnormality of serum amino acid levels (HP:0003112)2.10048015
57Abnormality of the 2nd finger (HP:0004100)2.10039059
58Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.08967007
59Degeneration of the lateral corticospinal tracts (HP:0002314)2.08967007
60Abnormality of the phalanges of the hallux (HP:0010057)2.07411580
61Hypoplasia of the ulna (HP:0003022)2.03147345
62Brushfield spots (HP:0001088)2.01840302
63Parakeratosis (HP:0001036)2.01697139
64Increased intramyocellular lipid droplets (HP:0012240)2.00797872
65Increased muscle lipid content (HP:0009058)1.99593890
66Progressive macrocephaly (HP:0004481)1.98904740
67Medial flaring of the eyebrow (HP:0010747)1.98353027
68Diminished movement (HP:0002374)1.97869058
69Pancreatic cysts (HP:0001737)1.94357985
70Depressed nasal ridge (HP:0000457)1.92911401
71Abnormality of the phalanges of the 5th finger (HP:0004213)1.91770293
72Pendular nystagmus (HP:0012043)1.91177631
73Abnormal number of incisors (HP:0011064)1.90223382
74Tubulointerstitial nephritis (HP:0001970)1.88251760
75Decreased central vision (HP:0007663)1.87966341
76CNS demyelination (HP:0007305)1.87175735
77Gait imbalance (HP:0002141)1.85455642
783-Methylglutaconic aciduria (HP:0003535)1.85121609
79Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.84193696
80Colon cancer (HP:0003003)1.83817018
81Abnormality of the corticospinal tract (HP:0002492)1.83215543
82Carpal bone hypoplasia (HP:0001498)1.81416398
83Impulsivity (HP:0100710)1.80323967
84Congenital primary aphakia (HP:0007707)1.79967313
85Decreased activity of mitochondrial respiratory chain (HP:0008972)1.79181998
86Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.79181998
87Focal dystonia (HP:0004373)1.78661990
88Increased serum lactate (HP:0002151)1.78501430
89True hermaphroditism (HP:0010459)1.78235724
90Renal tubular dysfunction (HP:0000124)1.77614948
91Craniofacial dystonia (HP:0012179)1.77067680
92Aplasia/Hypoplasia of the ulna (HP:0006495)1.76897230
93Short femoral neck (HP:0100864)1.76823864
94Nephrogenic diabetes insipidus (HP:0009806)1.76526394
95Symphalangism affecting the phalanges of the hand (HP:0009773)1.74944983
96Exertional dyspnea (HP:0002875)1.73930257
97Ketosis (HP:0001946)1.72576099
98Abnormality of renal resorption (HP:0011038)1.71129252
99Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.70426082
100Adrenal hypoplasia (HP:0000835)1.69242945

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERN14.46835612
2ADRBK23.00633912
3BCKDK2.91795063
4TXK2.74150125
5PDK22.57777648
6TIE12.49460968
7MAP2K62.36381828
8GRK12.30482665
9WNK42.10140576
10KDR2.03619947
11DYRK21.97306891
12ZAK1.68380365
13MAP4K21.65346455
14PIK3CA1.64067317
15PASK1.58422415
16NUAK11.54707193
17TESK21.49168541
18WNK31.46658996
19LIMK11.40974134
20BMPR1B1.40881981
21STK161.38186010
22ADRBK11.32802387
23PINK11.32279178
24INSRR1.31337949
25TEC1.26481892
26CASK1.22959336
27FRK1.22861608
28MAP3K111.20419567
29PRKCH1.18937514
30MAP2K71.18478210
31MUSK1.18015486
32TLK11.10076945
33LCK1.08737435
34AURKA1.08494360
35GRK71.08434189
36EPHB21.05727871
37LRRK21.04973080
38MAP4K11.03793694
39PKN11.01829144
40EPHA41.01786447
41VRK21.01506315
42PRKCQ0.98302789
43SYK0.96198813
44NTRK20.94908034
45ITK0.94548537
46STK390.92512817
47AKT20.91973018
48OBSCN0.91221136
49DYRK1B0.89840171
50PRKCG0.81498158
51NME20.77887722
52NEK20.77661482
53PRKACA0.76990792
54RPS6KA60.75844664
55TGFBR10.75455360
56MAP2K20.74744882
57ABL20.74176617
58EPHA30.73809247
59VRK10.72941277
60MAPK150.71868153
61PIM10.71867436
62CDK190.71862200
63MAPK130.71632920
64MAP2K40.71133265
65CSNK2A20.70796042
66STK30.70795670
67TNK20.70526460
68TAOK30.66785156
69CSNK2A10.66310507
70CAMK2A0.65594307
71PRKCA0.64539180
72MINK10.57926291
73CDC70.56741969
74TYRO30.56641896
75DAPK30.56499084
76OXSR10.56358771
77IKBKE0.55529467
78BTK0.54813269
79PLK40.54552435
80RPS6KC10.53227218
81RPS6KL10.53227218
82ATR0.51349554
83GRK50.51345248
84CAMK10.50762797
85FES0.50026575
86BRAF0.49594596
87PIK3CG0.47122121
88CSNK1A10.46600343
89MAP3K60.46167890
90PRKCD0.45987912
91NEK10.45983418
92PRKD20.45513561
93ROCK10.44632941
94RPS6KB10.43778583
95RPS6KA50.43006414
96PLK10.42418219
97INSR0.41097526
98DAPK20.39575974
99CSNK1G30.37857664
100PIM20.37622059

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030107.11664838
2Oxidative phosphorylation_Homo sapiens_hsa001903.71886557
3Parkinsons disease_Homo sapiens_hsa050123.22755535
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.59682525
5Cardiac muscle contraction_Homo sapiens_hsa042602.49736531
6Alzheimers disease_Homo sapiens_hsa050102.27632140
7Huntingtons disease_Homo sapiens_hsa050162.15509531
8Primary immunodeficiency_Homo sapiens_hsa053402.13333588
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.05743140
10Linoleic acid metabolism_Homo sapiens_hsa005912.02396418
11Proteasome_Homo sapiens_hsa030501.99237373
12Sulfur metabolism_Homo sapiens_hsa009201.95503859
13Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.94226548
14Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.87380582
15RNA polymerase_Homo sapiens_hsa030201.81602188
16Phototransduction_Homo sapiens_hsa047441.74338101
17RNA degradation_Homo sapiens_hsa030181.66412326
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.61600909
19Autoimmune thyroid disease_Homo sapiens_hsa053201.55638554
20Allograft rejection_Homo sapiens_hsa053301.55419398
21Protein export_Homo sapiens_hsa030601.49526734
22Graft-versus-host disease_Homo sapiens_hsa053321.41304554
23Nitrogen metabolism_Homo sapiens_hsa009101.36093284
24Olfactory transduction_Homo sapiens_hsa047401.23179235
25Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20388216
26Propanoate metabolism_Homo sapiens_hsa006401.18742679
27Asthma_Homo sapiens_hsa053101.18172606
28Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.15061421
29Butanoate metabolism_Homo sapiens_hsa006501.12415799
30Type I diabetes mellitus_Homo sapiens_hsa049401.11464869
31Sulfur relay system_Homo sapiens_hsa041221.06670421
32Nicotine addiction_Homo sapiens_hsa050331.05556964
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05534204
34Regulation of autophagy_Homo sapiens_hsa041401.05492834
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04792064
36Caffeine metabolism_Homo sapiens_hsa002321.03457927
37Basal transcription factors_Homo sapiens_hsa030221.02843432
38Peroxisome_Homo sapiens_hsa041461.02368963
39Ether lipid metabolism_Homo sapiens_hsa005651.00332555
40Arachidonic acid metabolism_Homo sapiens_hsa005900.99242216
41Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.98845101
42Maturity onset diabetes of the young_Homo sapiens_hsa049500.98189099
43Steroid hormone biosynthesis_Homo sapiens_hsa001400.92224346
44Tryptophan metabolism_Homo sapiens_hsa003800.90921107
45Retinol metabolism_Homo sapiens_hsa008300.87262139
46Intestinal immune network for IgA production_Homo sapiens_hsa046720.85487515
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.85296067
48Hematopoietic cell lineage_Homo sapiens_hsa046400.83786997
49Homologous recombination_Homo sapiens_hsa034400.79098058
50Pyrimidine metabolism_Homo sapiens_hsa002400.78801784
51Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.76539596
52Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.76178518
53Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.74941580
54Basal cell carcinoma_Homo sapiens_hsa052170.73516192
55Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70209909
56Hedgehog signaling pathway_Homo sapiens_hsa043400.69163794
57Chemical carcinogenesis_Homo sapiens_hsa052040.68847711
58Taste transduction_Homo sapiens_hsa047420.67124003
59Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.66230891
60Fructose and mannose metabolism_Homo sapiens_hsa000510.65461885
61Antigen processing and presentation_Homo sapiens_hsa046120.65277438
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65202370
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.63955077
64Fat digestion and absorption_Homo sapiens_hsa049750.63660606
65Purine metabolism_Homo sapiens_hsa002300.62051356
66SNARE interactions in vesicular transport_Homo sapiens_hsa041300.61633450
67Selenocompound metabolism_Homo sapiens_hsa004500.61238384
68Steroid biosynthesis_Homo sapiens_hsa001000.60221895
69Morphine addiction_Homo sapiens_hsa050320.59657704
70Metabolic pathways_Homo sapiens_hsa011000.56761522
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.54508174
72Collecting duct acid secretion_Homo sapiens_hsa049660.54112632
73Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.52837220
74Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.51468245
75T cell receptor signaling pathway_Homo sapiens_hsa046600.49601841
76Drug metabolism - other enzymes_Homo sapiens_hsa009830.48519482
77GABAergic synapse_Homo sapiens_hsa047270.47948732
78Fanconi anemia pathway_Homo sapiens_hsa034600.47139753
79Rheumatoid arthritis_Homo sapiens_hsa053230.45818542
80Serotonergic synapse_Homo sapiens_hsa047260.45206760
81One carbon pool by folate_Homo sapiens_hsa006700.44553536
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.43568939
83Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.40128276
84Insulin secretion_Homo sapiens_hsa049110.38175593
85Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36887554
86Systemic lupus erythematosus_Homo sapiens_hsa053220.36207438
87Primary bile acid biosynthesis_Homo sapiens_hsa001200.34432778
88RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.33971128
89Malaria_Homo sapiens_hsa051440.33539368
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.31667123
91Ovarian steroidogenesis_Homo sapiens_hsa049130.28628911
92Nucleotide excision repair_Homo sapiens_hsa034200.26753406
93Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.24103656
94Circadian entrainment_Homo sapiens_hsa047130.23745820
95Mismatch repair_Homo sapiens_hsa034300.22639546
96Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21037015
97Cholinergic synapse_Homo sapiens_hsa047250.20700315
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.20006108
99Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.18530471
100Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.18277318

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