RPS20P35

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1gamma-aminobutyric acid transport (GO:0015812)7.41796522
2nonmotile primary cilium assembly (GO:0035058)6.14537817
3cellular biogenic amine catabolic process (GO:0042402)5.72381241
4amine catabolic process (GO:0009310)5.72381241
5telomere maintenance via semi-conservative replication (GO:0032201)5.21906241
6DNA replication initiation (GO:0006270)5.15544164
7response to muscle activity (GO:0014850)5.08194543
8glycine transport (GO:0015816)4.84861904
9protein K6-linked ubiquitination (GO:0085020)4.81417540
10DNA deamination (GO:0045006)4.73926029
11telomere maintenance via recombination (GO:0000722)4.58213092
12translational termination (GO:0006415)4.44853309
13viral transcription (GO:0019083)4.40205052
14cornea development in camera-type eye (GO:0061303)4.31982095
15behavioral response to nicotine (GO:0035095)4.31428478
16response to gravity (GO:0009629)4.16873826
17negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)4.09047874
18ribosomal small subunit assembly (GO:0000028)4.07029001
19striated muscle atrophy (GO:0014891)4.00427142
20translational elongation (GO:0006414)3.98950851
21otic vesicle formation (GO:0030916)3.98799748
22mitochondrion transport along microtubule (GO:0047497)3.94200253
23establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.94200253
24establishment of mitochondrion localization (GO:0051654)3.93004871
25resolution of meiotic recombination intermediates (GO:0000712)3.91677544
26mitotic recombination (GO:0006312)3.90882663
27respiratory system process (GO:0003016)3.81867392
28seminiferous tubule development (GO:0072520)3.71243248
29cerebellar Purkinje cell differentiation (GO:0021702)3.69910901
30skeletal muscle adaptation (GO:0043501)3.66747568
31genetic imprinting (GO:0071514)3.65057220
32regulation of cilium movement (GO:0003352)3.59320038
33cAMP catabolic process (GO:0006198)3.59145065
34ribosomal large subunit biogenesis (GO:0042273)3.59092942
35SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.58592669
36ribosomal small subunit biogenesis (GO:0042274)3.56279046
37DNA strand elongation involved in DNA replication (GO:0006271)3.55478931
38regulation of centriole replication (GO:0046599)3.55411345
39cotranslational protein targeting to membrane (GO:0006613)3.51553183
40muscle atrophy (GO:0014889)3.50931424
41protein-cofactor linkage (GO:0018065)3.49041614
42skeletal muscle tissue regeneration (GO:0043403)3.48802253
43protein targeting to ER (GO:0045047)3.46798190
44cardiovascular system development (GO:0072358)3.45629639
45maturation of 5.8S rRNA (GO:0000460)3.44541104
46cytokinetic process (GO:0032506)3.43559961
47response to xenobiotic stimulus (GO:0009410)3.43333054
48cell migration in hindbrain (GO:0021535)3.42736046
49axon extension (GO:0048675)3.39285045
50hematopoietic stem cell differentiation (GO:0060218)3.34765749
51cellular protein complex disassembly (GO:0043624)3.32234561
52DNA strand elongation (GO:0022616)3.31729387
53maturation of SSU-rRNA (GO:0030490)3.31023211
54establishment of protein localization to endoplasmic reticulum (GO:0072599)3.29432543
55negative regulation of DNA-templated transcription, elongation (GO:0032785)3.29384720
56actin-myosin filament sliding (GO:0033275)3.27121046
57muscle filament sliding (GO:0030049)3.27121046
58eyelid development in camera-type eye (GO:0061029)3.26356232
59skeletal muscle organ development (GO:0060538)3.25603063
60protein localization to endoplasmic reticulum (GO:0070972)3.22294347
61viral life cycle (GO:0019058)3.19843333
62telomere maintenance via telomere lengthening (GO:0010833)3.19687233
63negative regulation of axonogenesis (GO:0050771)3.17060664
64nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.15594281
65negative regulation of reactive oxygen species metabolic process (GO:2000378)3.15174819
66ribonucleoprotein complex biogenesis (GO:0022613)3.10631151
67negative regulation of organelle assembly (GO:1902116)3.08742229
68kynurenine metabolic process (GO:0070189)3.05554612
69translational initiation (GO:0006413)3.04847322
70behavioral response to ethanol (GO:0048149)3.02044380
71negative regulation of transcription by competitive promoter binding (GO:0010944)3.01599468
72rRNA processing (GO:0006364)2.97455597
73rRNA metabolic process (GO:0016072)2.92292354
74regulation of immunoglobulin secretion (GO:0051023)2.89964606
75cell differentiation in hindbrain (GO:0021533)2.89769093
76oligosaccharide biosynthetic process (GO:0009312)2.89742020
77negative regulation of appetite (GO:0032099)2.88666875
78negative regulation of response to food (GO:0032096)2.88666875
79protein complex disassembly (GO:0043241)2.87767167
80cyclic nucleotide catabolic process (GO:0009214)2.86718969
81axonal fasciculation (GO:0007413)2.85922833
82macromolecular complex disassembly (GO:0032984)2.84589879
83neuron projection extension (GO:1990138)2.83508133
84ribosome biogenesis (GO:0042254)2.83083121
85pattern specification involved in kidney development (GO:0061004)2.80465787
86protein localization to microtubule cytoskeleton (GO:0072698)2.78850965
87chaperone-mediated protein transport (GO:0072321)2.77754716
88pyrimidine nucleobase catabolic process (GO:0006208)2.76526137
89mechanosensory behavior (GO:0007638)2.76392336
90keratinocyte development (GO:0003334)2.75905814
91positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.74314615
92cell proliferation in forebrain (GO:0021846)2.72994999
93detection of light stimulus involved in visual perception (GO:0050908)2.70791580
94detection of light stimulus involved in sensory perception (GO:0050962)2.70791580
95substrate-independent telencephalic tangential migration (GO:0021826)2.70501426
96substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.70501426
97head development (GO:0060322)2.68996299
98somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.68797146
99isotype switching (GO:0045190)2.68797146
100somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.68797146

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1VDR_22108803_ChIP-Seq_LS180_Human5.77118765
2EZH2_22144423_ChIP-Seq_EOC_Human5.01252640
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.40977097
4STAT6_21828071_ChIP-Seq_BEAS2B_Human3.21432676
5BMI1_23680149_ChIP-Seq_NPCS_Mouse2.99992443
6EED_16625203_ChIP-ChIP_MESCs_Mouse2.67764829
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.62455056
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.34427727
9GABP_17652178_ChIP-ChIP_JURKAT_Human2.26701184
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.22654645
11GBX2_23144817_ChIP-Seq_PC3_Human2.21001695
12CBX2_27304074_Chip-Seq_ESCs_Mouse2.19686167
13RNF2_27304074_Chip-Seq_NSC_Mouse2.15744668
14RBPJ_22232070_ChIP-Seq_NCS_Mouse2.14379718
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.12408338
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.08372560
17EZH2_18974828_ChIP-Seq_MESCs_Mouse2.05619475
18RNF2_18974828_ChIP-Seq_MESCs_Mouse2.05619475
19ZNF274_21170338_ChIP-Seq_K562_Hela2.03740206
20CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.03534058
21FUS_26573619_Chip-Seq_HEK293_Human1.86350885
22PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.80134834
23CTBP1_25329375_ChIP-Seq_LNCAP_Human1.78487264
24RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.74754366
25REST_21632747_ChIP-Seq_MESCs_Mouse1.73908856
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.73607481
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.71883977
28TAF15_26573619_Chip-Seq_HEK293_Human1.70703571
29MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.66742790
30E2F4_17652178_ChIP-ChIP_JURKAT_Human1.66415071
31TTF2_22483619_ChIP-Seq_HELA_Human1.63585029
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.60006704
33TP53_22573176_ChIP-Seq_HFKS_Human1.59144967
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.57086415
35EWS_26573619_Chip-Seq_HEK293_Human1.55891949
36ELK1_19687146_ChIP-ChIP_HELA_Human1.55815833
37HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.55371012
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.55047586
39KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.54535431
40YY1_21170310_ChIP-Seq_MESCs_Mouse1.50877119
41IGF1R_20145208_ChIP-Seq_DFB_Human1.50523970
42SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.48556880
43ERG_21242973_ChIP-ChIP_JURKAT_Human1.43171942
44ETS1_20019798_ChIP-Seq_JURKAT_Human1.43008775
45TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.42053694
46POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.42053694
47JARID2_20075857_ChIP-Seq_MESCs_Mouse1.39997211
48EST1_17652178_ChIP-ChIP_JURKAT_Human1.38739322
49TP63_19390658_ChIP-ChIP_HaCaT_Human1.38314979
50KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.38055969
51RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.31790472
52TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.29227136
53MYC_18940864_ChIP-ChIP_HL60_Human1.28938933
54CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.28512055
55MYC_18555785_ChIP-Seq_MESCs_Mouse1.26101226
56POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.25578609
57NCOR_22424771_ChIP-Seq_293T_Human1.22937397
58SUZ12_27294783_Chip-Seq_ESCs_Mouse1.19774614
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.18563239
60CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.18535842
61ZFP57_27257070_Chip-Seq_ESCs_Mouse1.15700214
62MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.14690198
63KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.13253091
64MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.11085600
65NANOG_20526341_ChIP-Seq_ESCs_Human1.10741889
66CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10177389
67GATA3_21878914_ChIP-Seq_MCF-7_Human1.09034971
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.08669996
69SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.08086261
70CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.07377656
71SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.06635359
72FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.06509468
73MYC_19079543_ChIP-ChIP_MESCs_Mouse1.06251658
74VDR_23849224_ChIP-Seq_CD4+_Human1.06078743
75P300_19829295_ChIP-Seq_ESCs_Human1.04352468
76POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04187567
77AR_20517297_ChIP-Seq_VCAP_Human1.03211750
78SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.01394301
79SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99341772
80REST_18959480_ChIP-ChIP_MESCs_Mouse0.98954877
81AHR_22903824_ChIP-Seq_MCF-7_Human0.98623751
82TCF4_23295773_ChIP-Seq_U87_Human0.98571543
83SOX2_18555785_ChIP-Seq_MESCs_Mouse0.97034454
84MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse0.95614003
85TP53_20018659_ChIP-ChIP_R1E_Mouse0.94887787
86ERA_21632823_ChIP-Seq_H3396_Human0.93478130
87PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.93347775
88TOP2B_26459242_ChIP-Seq_MCF-7_Human0.92740263
89IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.91858998
90CBP_20019798_ChIP-Seq_JUKART_Human0.91858998
91PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.91510767
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.91193071
93TDRD3_21172665_ChIP-Seq_MCF-7_Human0.90919816
94FLI1_27457419_Chip-Seq_LIVER_Mouse0.90599890
95FOXH1_21741376_ChIP-Seq_EPCs_Human0.89516541
96MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human0.87380089
97SMAD3_21741376_ChIP-Seq_ESCs_Human0.87312086
98AUTS2_25519132_ChIP-Seq_293T-REX_Human0.87194517
99IKZF1_21737484_ChIP-ChIP_HCT116_Human0.87105942
100TAF2_19829295_ChIP-Seq_ESCs_Human0.86655790

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004858_abnormal_nervous_system9.42727720
2MP0003122_maternal_imprinting4.34598597
3MP0004142_abnormal_muscle_tone4.22300968
4MP0006292_abnormal_olfactory_placode3.90189423
5MP0005423_abnormal_somatic_nervous3.69116843
6MP0000569_abnormal_digit_pigmentation2.98547484
7MP0003121_genomic_imprinting2.82584961
8MP0006276_abnormal_autonomic_nervous2.82533324
9MP0000013_abnormal_adipose_tissue2.55139029
10MP0002138_abnormal_hepatobiliary_system2.33529264
11MP0004145_abnormal_muscle_electrophysio2.23568964
12MP0001188_hyperpigmentation2.19098355
13MP0003880_abnormal_central_pattern2.14492680
14MP0000372_irregular_coat_pigmentation2.03783526
15MP0001529_abnormal_vocalization1.88030515
16MP0009379_abnormal_foot_pigmentation1.87633291
17MP0004885_abnormal_endolymph1.80576950
18MP0002184_abnormal_innervation1.79411770
19MP0001440_abnormal_grooming_behavior1.79236102
20MP0003879_abnormal_hair_cell1.70871711
21MP0008789_abnormal_olfactory_epithelium1.60844474
22MP0003075_altered_response_to1.57652999
23MP0008260_abnormal_autophagy1.55708646
24MP0002736_abnormal_nociception_after1.52862222
25MP0000747_muscle_weakness1.48306050
26MP0005645_abnormal_hypothalamus_physiol1.45370635
27MP0001853_heart_inflammation1.42753206
28MP0008057_abnormal_DNA_replication1.38191609
29MP0003123_paternal_imprinting1.37512901
30MP0001986_abnormal_taste_sensitivity1.37061428
31MP0003787_abnormal_imprinting1.35179348
32MP0000778_abnormal_nervous_system1.28656562
33MP0002272_abnormal_nervous_system1.28185723
34MP0002938_white_spotting1.27977114
35MP0005551_abnormal_eye_electrophysiolog1.27237265
36MP0003385_abnormal_body_wall1.26493508
37MP0002876_abnormal_thyroid_physiology1.20321921
38MP0001968_abnormal_touch/_nociception1.20120439
39MP0002063_abnormal_learning/memory/cond1.15087041
40MP0000631_abnormal_neuroendocrine_gland1.14454448
41MP0001984_abnormal_olfaction1.13183333
42MP0003646_muscle_fatigue1.10523976
43MP0002160_abnormal_reproductive_system1.08706694
44MP0009046_muscle_twitch1.08631965
45MP0008877_abnormal_DNA_methylation1.06620924
46MP0004924_abnormal_behavior1.05707109
47MP0005386_behavior/neurological_phenoty1.05707109
48MP0003567_abnormal_fetal_cardiomyocyte1.04298046
49MP0005499_abnormal_olfactory_system1.02882294
50MP0005394_taste/olfaction_phenotype1.02882294
51MP0000049_abnormal_middle_ear1.01255034
52MP0002163_abnormal_gland_morphology0.99512052
53MP0006072_abnormal_retinal_apoptosis0.96938371
54MP0003828_pulmonary_edema0.95237858
55MP0002572_abnormal_emotion/affect_behav0.94866135
56MP0001485_abnormal_pinna_reflex0.93806347
57MP0004036_abnormal_muscle_relaxation0.88874245
58MP0000427_abnormal_hair_cycle0.86554556
59MP0002733_abnormal_thermal_nociception0.79929921
60MP0000955_abnormal_spinal_cord0.77261279
61MP0008058_abnormal_DNA_repair0.77258723
62MP0002882_abnormal_neuron_morphology0.76436593
63MP0002752_abnormal_somatic_nervous0.76161074
64MP0005174_abnormal_tail_pigmentation0.75773887
65MP0000647_abnormal_sebaceous_gland0.75452920
66MP0008770_decreased_survivor_rate0.74212811
67MP0003959_abnormal_lean_body0.73790923
68MP0010094_abnormal_chromosome_stability0.73594304
69MP0002837_dystrophic_cardiac_calcinosis0.72201358
70MP0003635_abnormal_synaptic_transmissio0.71184507
71MP0002557_abnormal_social/conspecific_i0.70238498
72MP0002277_abnormal_respiratory_mucosa0.69773577
73MP0000003_abnormal_adipose_tissue0.69132473
74MP0002734_abnormal_mechanical_nocicepti0.68568317
75MP0004742_abnormal_vestibular_system0.68092324
76MP0009745_abnormal_behavioral_response0.67266043
77MP0002269_muscular_atrophy0.67040190
78MP0005075_abnormal_melanosome_morpholog0.66888490
79MP0008872_abnormal_physiological_respon0.66734530
80MP0006035_abnormal_mitochondrial_morpho0.66669142
81MP0003942_abnormal_urinary_system0.64627142
82MP0002233_abnormal_nose_morphology0.64074263
83MP0001970_abnormal_pain_threshold0.63723522
84MP0002066_abnormal_motor_capabilities/c0.63578765
85MP0000566_synostosis0.62370221
86MP0001661_extended_life_span0.62272063
87MP0001293_anophthalmia0.61646086
88MP0001963_abnormal_hearing_physiology0.61183795
89MP0002095_abnormal_skin_pigmentation0.60117485
90MP0002067_abnormal_sensory_capabilities0.59811755
91MP0008775_abnormal_heart_ventricle0.59203143
92MP0005389_reproductive_system_phenotype0.58808489
93MP0000470_abnormal_stomach_morphology0.58413152
94MP0002106_abnormal_muscle_physiology0.57481675
95MP0001943_abnormal_respiration0.56749560
96MP0001324_abnormal_eye_pigmentation0.55162443
97MP0003861_abnormal_nervous_system0.54738363
98MP0005408_hypopigmentation0.51918785
99MP0004087_abnormal_muscle_fiber0.51665298
100MP0000026_abnormal_inner_ear0.51120858

Predicted human phenotypes

RankGene SetZ-score
1Failure to thrive in infancy (HP:0001531)6.45100261
2Abnormality of the labia minora (HP:0012880)5.05778704
3Oligomenorrhea (HP:0000876)4.96603788
4Pancreatic fibrosis (HP:0100732)4.70348627
5Gait imbalance (HP:0002141)4.67972425
6Abnormal hair whorl (HP:0010721)4.63793349
7True hermaphroditism (HP:0010459)4.33713451
8Congenital primary aphakia (HP:0007707)4.29666334
9Pancreatic cysts (HP:0001737)4.23402355
10Palpebral edema (HP:0100540)4.00846819
11Medial flaring of the eyebrow (HP:0010747)3.99037195
12Abnormality of midbrain morphology (HP:0002418)3.97800467
13Molar tooth sign on MRI (HP:0002419)3.97800467
14Poor coordination (HP:0002370)3.97488425
15Polyphagia (HP:0002591)3.89509382
16Nephrogenic diabetes insipidus (HP:0009806)3.72397888
17Poor suck (HP:0002033)3.69271484
18Reticulocytopenia (HP:0001896)3.64594820
19Abnormality of cells of the erythroid lineage (HP:0012130)3.59700894
20Aplasia/Hypoplasia of the tongue (HP:0010295)3.58822987
21Cystic liver disease (HP:0006706)3.15418599
22Specific learning disability (HP:0001328)3.02838405
23Nephronophthisis (HP:0000090)2.89464865
24Hip dysplasia (HP:0001385)2.87834987
25Vaginal atresia (HP:0000148)2.86984600
26Abnormality of DNA repair (HP:0003254)2.83678961
27Acute necrotizing encephalopathy (HP:0006965)2.82175848
28Global brain atrophy (HP:0002283)2.79086505
29Genital tract atresia (HP:0001827)2.74894620
30Sclerocornea (HP:0000647)2.74473492
31Renal cortical cysts (HP:0000803)2.73920100
32Polydipsia (HP:0001959)2.71458250
33Abnormal drinking behavior (HP:0030082)2.71458250
34Congenital stationary night blindness (HP:0007642)2.65745789
35Postaxial foot polydactyly (HP:0001830)2.65477250
36Pendular nystagmus (HP:0012043)2.64868270
37Generalized hypotonia (HP:0001290)2.64835176
38Abnormality of the renal cortex (HP:0011035)2.64635137
39Abnormal rod and cone electroretinograms (HP:0008323)2.57518506
40Abnormal mitochondria in muscle tissue (HP:0008316)2.52285028
41Absent rod-and cone-mediated responses on ERG (HP:0007688)2.43643854
42Anencephaly (HP:0002323)2.41045161
43Abnormality of the renal medulla (HP:0100957)2.38858336
44Stenosis of the external auditory canal (HP:0000402)2.37751592
45Microglossia (HP:0000171)2.35936358
46Progressive macrocephaly (HP:0004481)2.33678407
47Abnormality of the aortic arch (HP:0012303)2.32962441
48Absent thumb (HP:0009777)2.32700213
49Abnormality of the nasal septum (HP:0000419)2.30391058
50Abnormal number of erythroid precursors (HP:0012131)2.29383988
51Decreased muscle mass (HP:0003199)2.28218522
52Acute encephalopathy (HP:0006846)2.25279896
53Status epilepticus (HP:0002133)2.22828998
54Macrocytic anemia (HP:0001972)2.22213685
55Morphological abnormality of the middle ear (HP:0008609)2.22165023
56Nasal speech (HP:0001611)2.20630406
57Sleep apnea (HP:0010535)2.19133987
58Periorbital edema (HP:0100539)2.15650682
59Febrile seizures (HP:0002373)2.14953854
60Astigmatism (HP:0000483)2.09230891
61Abnormality of the renal collecting system (HP:0004742)2.07290130
62Congenital hepatic fibrosis (HP:0002612)2.06376713
63Male pseudohermaphroditism (HP:0000037)2.05804415
64Growth hormone deficiency (HP:0000824)2.03287002
65Aplasia/Hypoplasia of the uvula (HP:0010293)2.02813093
66Facial edema (HP:0000282)2.02353859
67Aplasia/Hypoplasia of the lens (HP:0008063)2.02025964
68Abnormality of the ileum (HP:0001549)2.01624904
69Distal arthrogryposis (HP:0005684)2.01577475
70Meckel diverticulum (HP:0002245)2.01012149
71Horseshoe kidney (HP:0000085)2.00316180
72Short foot (HP:0001773)1.98581482
73Fair hair (HP:0002286)1.97243381
74Cutaneous photosensitivity (HP:0000992)1.96993054
75Epileptic encephalopathy (HP:0200134)1.95446729
76Abnormal eating behavior (HP:0100738)1.93189646
77Decreased testicular size (HP:0008734)1.90936385
78Lip pit (HP:0100267)1.90367143
79Pallor (HP:0000980)1.87629914
80Aganglionic megacolon (HP:0002251)1.86539395
81Absent phalangeal crease (HP:0006109)1.85151690
82Narrow nasal bridge (HP:0000446)1.84777578
83Chromosomal breakage induced by crosslinking agents (HP:0003221)1.81962226
84Progressive microcephaly (HP:0000253)1.81137492
85Scrotal hypoplasia (HP:0000046)1.80592594
86Calcaneovalgus deformity (HP:0001848)1.80054842
87Narrow forehead (HP:0000341)1.79076102
88Decreased subcutaneous fat (HP:0001002)1.78282071
89Abnormality of the carotid arteries (HP:0005344)1.78041391
90Optic disc pallor (HP:0000543)1.76731432
91Abnormal finger flexion creases (HP:0006143)1.74253937
92Broad-based gait (HP:0002136)1.73594618
93Atonic seizures (HP:0010819)1.73441076
94Furrowed tongue (HP:0000221)1.72494562
95Ulnar deviation of the wrist (HP:0003049)1.71890631
96Polyuria (HP:0000103)1.71776840
97Hypoplastic female external genitalia (HP:0012815)1.71492771
98Increased CSF lactate (HP:0002490)1.70186063
99Labial hypoplasia (HP:0000066)1.69535915
100Cerebral edema (HP:0002181)1.68554034

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PRKD34.14387624
2CASK3.78698615
3PINK13.78671192
4DYRK23.09519860
5MAPK133.04833962
6WNK43.02608946
7CDK192.98838261
8CAMKK22.96183737
9PHKG12.65930702
10PHKG22.65930702
11CDC72.39806553
12CAMK12.08259215
13TIE12.00028833
14STK391.78359394
15CAMK1G1.59904113
16CAMK1D1.57399741
17FRK1.56424122
18OXSR11.55940605
19CAMKK11.51509285
20EPHA31.48237829
21IRAK11.48111384
22DYRK31.46152624
23OBSCN1.41178029
24DYRK1B1.40819484
25LRRK21.40726454
26ADRBK21.40002553
27PIK3CA1.39475422
28BRSK21.39181829
29PDK21.29611897
30PRKCI1.12444771
31RPS6KA21.12005633
32LMTK21.04766176
33CHEK21.01463317
34MAP4K20.99960427
35BRAF0.98176772
36PRKCG0.96368882
37WNK30.96185652
38RPS6KA60.95330439
39EEF2K0.94892474
40PRKCQ0.91132683
41GRK10.90153517
42PRKAA10.88104629
43RPS6KL10.87582155
44RPS6KC10.87582155
45TAOK30.86822816
46NEK10.81878756
47MAP3K90.81814160
48RPS6KA10.81537980
49SRPK10.77928703
50TYRO30.76967307
51WNK10.76120870
52PNCK0.75996731
53BMPR1B0.75012577
54MARK10.74888936
55TLK10.73262012
56PRKCH0.72334243
57TXK0.71729366
58PASK0.70732064
59CDK80.68608144
60MKNK20.65966535
61PRKG20.65856885
62SIK20.65764794
63PIK3CG0.65441163
64MAPKAPK50.64489211
65NME10.64450182
66ARAF0.64154454
67RPS6KA50.63813636
68ZAK0.63681206
69ABL20.60393944
70STK110.60257123
71PRKCZ0.58869116
72PIM10.56211671
73TNIK0.53851703
74PLK40.53536890
75EPHB20.52534892
76AURKB0.51289302
77NUAK10.50765722
78ATR0.47718591
79CSNK1E0.45663187
80AURKA0.44608814
81TTK0.44477929
82DYRK1A0.43022668
83BRSK10.42097757
84CSNK2A10.41831281
85HIPK20.41805622
86PRKACA0.40639585
87TRPM70.40122076
88PBK0.39621671
89PRKD10.38978641
90PLK20.37960696
91RPS6KA40.35765583
92PRKDC0.35365591
93INSRR0.35333943
94NEK20.34706602
95PRKD20.33993661
96ALK0.33673321
97PRKACB0.33404856
98PLK10.33399286
99RPS6KA30.33367045
100CSNK2A20.32895641

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur relay system_Homo sapiens_hsa041225.29363037
2Ribosome_Homo sapiens_hsa030104.04695730
3DNA replication_Homo sapiens_hsa030303.82154370
4Steroid biosynthesis_Homo sapiens_hsa001003.43927705
5Basal transcription factors_Homo sapiens_hsa030222.94650446
6Dorso-ventral axis formation_Homo sapiens_hsa043202.81679381
7Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006042.75534008
8Regulation of autophagy_Homo sapiens_hsa041402.51312464
9Fanconi anemia pathway_Homo sapiens_hsa034602.38484045
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.13317461
11One carbon pool by folate_Homo sapiens_hsa006702.07394547
12Pyrimidine metabolism_Homo sapiens_hsa002401.91445601
13RNA degradation_Homo sapiens_hsa030181.76391376
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.71361146
15Nicotine addiction_Homo sapiens_hsa050331.70154696
16Homologous recombination_Homo sapiens_hsa034401.65155700
17Protein export_Homo sapiens_hsa030601.58524207
18Nitrogen metabolism_Homo sapiens_hsa009101.56903144
19Cardiac muscle contraction_Homo sapiens_hsa042601.55267177
20Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.51217392
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.49091232
22Oxidative phosphorylation_Homo sapiens_hsa001901.47848349
23RNA polymerase_Homo sapiens_hsa030201.43856435
24Nucleotide excision repair_Homo sapiens_hsa034201.42367330
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.39041334
26Morphine addiction_Homo sapiens_hsa050321.37710605
27Parkinsons disease_Homo sapiens_hsa050121.21934734
28Linoleic acid metabolism_Homo sapiens_hsa005911.16092765
29Butanoate metabolism_Homo sapiens_hsa006501.11301610
30Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.08643643
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.08099656
32Purine metabolism_Homo sapiens_hsa002301.06046050
33Oxytocin signaling pathway_Homo sapiens_hsa049211.00614144
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.00587659
35Fatty acid biosynthesis_Homo sapiens_hsa000610.97678381
36Phototransduction_Homo sapiens_hsa047440.97601970
37Primary immunodeficiency_Homo sapiens_hsa053400.93479832
38Huntingtons disease_Homo sapiens_hsa050160.91138746
39Alzheimers disease_Homo sapiens_hsa050100.88995895
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84439187
41Spliceosome_Homo sapiens_hsa030400.84232164
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.80995754
43RNA transport_Homo sapiens_hsa030130.80024234
44Proteasome_Homo sapiens_hsa030500.79605981
45Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.76543696
46Insulin secretion_Homo sapiens_hsa049110.76279137
47Systemic lupus erythematosus_Homo sapiens_hsa053220.75478252
48GABAergic synapse_Homo sapiens_hsa047270.73609357
49Asthma_Homo sapiens_hsa053100.72797276
50Mismatch repair_Homo sapiens_hsa034300.71703540
51Olfactory transduction_Homo sapiens_hsa047400.70615093
52Hedgehog signaling pathway_Homo sapiens_hsa043400.70494613
53Axon guidance_Homo sapiens_hsa043600.68556870
54Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.67878973
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.65993390
56Adipocytokine signaling pathway_Homo sapiens_hsa049200.64231230
57Tight junction_Homo sapiens_hsa045300.64139568
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64132306
59Renin secretion_Homo sapiens_hsa049240.62207843
60Steroid hormone biosynthesis_Homo sapiens_hsa001400.61498715
61Arginine and proline metabolism_Homo sapiens_hsa003300.59627843
62Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57836571
63Longevity regulating pathway - mammal_Homo sapiens_hsa042110.57435704
64Pyruvate metabolism_Homo sapiens_hsa006200.56548621
65Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56075246
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.55724780
67ABC transporters_Homo sapiens_hsa020100.54603885
68Alcoholism_Homo sapiens_hsa050340.54361366
69Chemical carcinogenesis_Homo sapiens_hsa052040.53664591
70AMPK signaling pathway_Homo sapiens_hsa041520.52948905
71Aldosterone synthesis and secretion_Homo sapiens_hsa049250.52445806
72mTOR signaling pathway_Homo sapiens_hsa041500.51532349
73Calcium signaling pathway_Homo sapiens_hsa040200.50435409
74Synaptic vesicle cycle_Homo sapiens_hsa047210.49765669
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.47163661
76Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.46310658
77Intestinal immune network for IgA production_Homo sapiens_hsa046720.40924629
78Basal cell carcinoma_Homo sapiens_hsa052170.38899133
79Peroxisome_Homo sapiens_hsa041460.37688287
80Tryptophan metabolism_Homo sapiens_hsa003800.36495709
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.35792013
82Arachidonic acid metabolism_Homo sapiens_hsa005900.33774428
83Metabolic pathways_Homo sapiens_hsa011000.33512719
84Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.33075405
85Propanoate metabolism_Homo sapiens_hsa006400.32675668
86Serotonergic synapse_Homo sapiens_hsa047260.31467108
87Glucagon signaling pathway_Homo sapiens_hsa049220.30353901
88Retinol metabolism_Homo sapiens_hsa008300.30301604
89Circadian entrainment_Homo sapiens_hsa047130.30098654
90Folate biosynthesis_Homo sapiens_hsa007900.29963539
91Drug metabolism - other enzymes_Homo sapiens_hsa009830.29584489
92cGMP-PKG signaling pathway_Homo sapiens_hsa040220.28322076
93Gastric acid secretion_Homo sapiens_hsa049710.27683331
94Salivary secretion_Homo sapiens_hsa049700.27411327
95Taste transduction_Homo sapiens_hsa047420.27344770
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.25109716
97Base excision repair_Homo sapiens_hsa034100.24944661
98Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.23925141
99Pancreatic secretion_Homo sapiens_hsa049720.21898758
100Vascular smooth muscle contraction_Homo sapiens_hsa042700.20681267

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