RPS20P5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.87294861
2translational termination (GO:0006415)7.65607902
3SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.82202746
4cotranslational protein targeting to membrane (GO:0006613)6.76611003
5protein targeting to ER (GO:0045047)6.69597323
6establishment of protein localization to endoplasmic reticulum (GO:0072599)6.36726236
7protein localization to endoplasmic reticulum (GO:0070972)6.21975701
8translational elongation (GO:0006414)6.21934144
9behavioral response to nicotine (GO:0035095)6.07204444
10cellular protein complex disassembly (GO:0043624)5.69913636
11viral life cycle (GO:0019058)5.53216181
12nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.47785941
13ribosomal small subunit biogenesis (GO:0042274)5.12548896
14response to xenobiotic stimulus (GO:0009410)5.06205525
15ribosomal large subunit biogenesis (GO:0042273)5.02467430
16protein complex disassembly (GO:0043241)4.75088696
17translational initiation (GO:0006413)4.74844081
18negative regulation of T cell differentiation in thymus (GO:0033085)4.73261657
19maturation of SSU-rRNA (GO:0030490)4.68973466
20protein targeting to membrane (GO:0006612)4.64403920
21establishment of protein localization to mitochondrial membrane (GO:0090151)4.64082108
22macromolecular complex disassembly (GO:0032984)4.45317482
23ribosomal small subunit assembly (GO:0000028)4.40940175
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.36764580
25mitochondrial respiratory chain complex I assembly (GO:0032981)4.36764580
26NADH dehydrogenase complex assembly (GO:0010257)4.36764580
27rRNA modification (GO:0000154)4.25901957
28protein complex biogenesis (GO:0070271)4.23822414
29pattern specification involved in kidney development (GO:0061004)4.15395095
30transcription elongation from RNA polymerase III promoter (GO:0006385)4.00444059
31termination of RNA polymerase III transcription (GO:0006386)4.00444059
32mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.00051235
33translation (GO:0006412)3.97307422
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.96042295
35nuclear-transcribed mRNA catabolic process (GO:0000956)3.91019977
36respiratory electron transport chain (GO:0022904)3.88388664
37electron transport chain (GO:0022900)3.84422870
38ATP synthesis coupled proton transport (GO:0015986)3.75800921
39energy coupled proton transport, down electrochemical gradient (GO:0015985)3.75800921
40mitochondrial respiratory chain complex assembly (GO:0033108)3.70834851
41kynurenine metabolic process (GO:0070189)3.67417869
42mRNA catabolic process (GO:0006402)3.65392958
43negative regulation of retinoic acid receptor signaling pathway (GO:0048387)3.50203066
44indolalkylamine metabolic process (GO:0006586)3.39299542
45aldehyde catabolic process (GO:0046185)3.37051711
46regulation of cellular respiration (GO:0043457)3.36676702
47indole-containing compound catabolic process (GO:0042436)3.33702200
48indolalkylamine catabolic process (GO:0046218)3.33702200
49tryptophan catabolic process (GO:0006569)3.33702200
50RNA catabolic process (GO:0006401)3.32346137
51glyoxylate metabolic process (GO:0046487)3.30430422
52protein localization to cilium (GO:0061512)3.29997869
53negative regulation of appetite (GO:0032099)3.29878825
54negative regulation of response to food (GO:0032096)3.29878825
55positive regulation of T cell apoptotic process (GO:0070234)3.28842100
56rRNA methylation (GO:0031167)3.25880243
57proteasome assembly (GO:0043248)3.20257269
58chaperone-mediated protein transport (GO:0072321)3.20139001
59GTP biosynthetic process (GO:0006183)3.18470352
60establishment of protein localization to membrane (GO:0090150)3.12151696
61cellular component biogenesis (GO:0044085)3.11500596
62ribonucleoprotein complex biogenesis (GO:0022613)3.09059467
63pyrimidine nucleobase catabolic process (GO:0006208)3.05338683
64respiratory chain complex IV assembly (GO:0008535)3.05039578
65centriole replication (GO:0007099)3.03127736
66negative regulation of organelle assembly (GO:1902116)3.02987726
67synaptic transmission, cholinergic (GO:0007271)2.96351245
68rRNA catabolic process (GO:0016075)2.93903056
69neuron fate determination (GO:0048664)2.93639658
70water-soluble vitamin biosynthetic process (GO:0042364)2.90727354
71CTP biosynthetic process (GO:0006241)2.89987083
72CTP metabolic process (GO:0046036)2.89987083
73regulation of retinoic acid receptor signaling pathway (GO:0048385)2.88928704
74protein targeting (GO:0006605)2.88140896
75cytochrome complex assembly (GO:0017004)2.87168691
76negative regulation of mast cell activation (GO:0033004)2.86516810
77negative regulation of transcription regulatory region DNA binding (GO:2000678)2.86109665
78hydrogen ion transmembrane transport (GO:1902600)2.84863912
79L-ascorbic acid metabolic process (GO:0019852)2.81091064
80negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.76423836
81proton transport (GO:0015992)2.73424911
82establishment of protein localization to organelle (GO:0072594)2.72230258
83epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.66917860
84hydrogen transport (GO:0006818)2.64947239
85male meiosis I (GO:0007141)2.63372048
86purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.62640952
87epithelial cilium movement (GO:0003351)2.60364530
88protein polyglutamylation (GO:0018095)2.60255872
89detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.57224972
90UTP biosynthetic process (GO:0006228)2.57037694
91dopamine biosynthetic process (GO:0042416)2.56978002
92intraciliary transport (GO:0042073)2.56769295
93interferon-gamma production (GO:0032609)2.56571482
94GPI anchor metabolic process (GO:0006505)2.55037077
95tryptophan metabolic process (GO:0006568)2.54264058
96GPI anchor biosynthetic process (GO:0006506)2.53212587
97nucleobase catabolic process (GO:0046113)2.52364195
98maternal behavior (GO:0042711)2.52067168
99cellular biogenic amine catabolic process (GO:0042402)2.52016720
100amine catabolic process (GO:0009310)2.52016720

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human8.06464448
2IRF1_19129219_ChIP-ChIP_H3396_Human2.71029025
3GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.68715972
4CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.54049361
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.48108055
6GABP_17652178_ChIP-ChIP_JURKAT_Human2.42750181
7VDR_22108803_ChIP-Seq_LS180_Human2.42183284
8MYC_18555785_ChIP-Seq_MESCs_Mouse2.41813354
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.37763527
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.36135100
11IKZF1_21737484_ChIP-ChIP_HCT116_Human2.31514113
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.24301662
13EZH2_27304074_Chip-Seq_ESCs_Mouse2.20533319
14CBX2_27304074_Chip-Seq_ESCs_Mouse2.19978268
15NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.14967953
16TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.04755058
17CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.95295242
18KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.93687228
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.91261960
20JARID2_20064375_ChIP-Seq_MESCs_Mouse1.76403813
21BMI1_23680149_ChIP-Seq_NPCS_Mouse1.74398226
22CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.72104837
23ETS1_20019798_ChIP-Seq_JURKAT_Human1.70665338
24MYC_18940864_ChIP-ChIP_HL60_Human1.69029361
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.61549842
26RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.60071375
27PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.60028158
28CTBP1_25329375_ChIP-Seq_LNCAP_Human1.55852940
29JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.55409591
30ZNF274_21170338_ChIP-Seq_K562_Hela1.54813530
31SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.53961487
32SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.46287565
33HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.44898945
34TTF2_22483619_ChIP-Seq_HELA_Human1.44805727
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.44581303
36SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.42985171
37REST_21632747_ChIP-Seq_MESCs_Mouse1.41462798
38SUZ12_27294783_Chip-Seq_ESCs_Mouse1.41239375
39TP53_22573176_ChIP-Seq_HFKS_Human1.39234028
40AUTS2_25519132_ChIP-Seq_293T-REX_Human1.31570180
41RNF2_18974828_ChIP-Seq_MESCs_Mouse1.31042978
42EZH2_18974828_ChIP-Seq_MESCs_Mouse1.31042978
43TAF2_19829295_ChIP-Seq_ESCs_Human1.30272651
44ETV2_25802403_ChIP-Seq_MESCs_Mouse1.30242681
45MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.29382642
46P53_22127205_ChIP-Seq_FIBROBLAST_Human1.28017497
47EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.26084598
48GATA1_26923725_Chip-Seq_HPCs_Mouse1.25677162
49GATA3_21878914_ChIP-Seq_MCF-7_Human1.25496979
50TP63_19390658_ChIP-ChIP_HaCaT_Human1.24334397
51CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.23113761
52SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22692600
53EWS_26573619_Chip-Seq_HEK293_Human1.20467076
54PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.20187196
55JARID2_20075857_ChIP-Seq_MESCs_Mouse1.19922568
56KLF5_20875108_ChIP-Seq_MESCs_Mouse1.19916993
57VDR_23849224_ChIP-Seq_CD4+_Human1.19122528
58SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.17441575
59RNF2_27304074_Chip-Seq_ESCs_Mouse1.17387244
60POU5F1_16153702_ChIP-ChIP_HESCs_Human1.15596953
61CBP_20019798_ChIP-Seq_JUKART_Human1.13949844
62IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.13949844
63KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.12743070
64SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.11857445
65MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.11173804
66BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.11160128
67TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10317998
68POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.10317998
69GBX2_23144817_ChIP-Seq_PC3_Human1.09059277
70FLI1_27457419_Chip-Seq_LIVER_Mouse1.07869804
71KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.07114541
72MYC_19829295_ChIP-Seq_ESCs_Human1.06851805
73UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06754580
74MYC_19079543_ChIP-ChIP_MESCs_Mouse1.06649432
75NCOR_22424771_ChIP-Seq_293T_Human1.06356712
76FOXA1_27270436_Chip-Seq_PROSTATE_Human1.05474886
77FOXA1_25329375_ChIP-Seq_VCAP_Human1.05474886
78ELK1_19687146_ChIP-ChIP_HELA_Human1.03658764
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.01459797
80CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.00280888
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98979053
82REST_18959480_ChIP-ChIP_MESCs_Mouse0.97848997
83ETV1_20927104_ChIP-Seq_GIST48_Human0.97775479
84GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.94525612
85RBPJ_22232070_ChIP-Seq_NCS_Mouse0.94322017
86RBPJ_21746931_ChIP-Seq_IB4_Human0.93041059
87FUS_26573619_Chip-Seq_HEK293_Human0.92794223
88RNF2_27304074_Chip-Seq_NSC_Mouse0.92688752
89CTCF_20526341_ChIP-Seq_ESCs_Human0.92659970
90RING1B_27294783_Chip-Seq_ESCs_Mouse0.92322122
91NANOG_20526341_ChIP-Seq_ESCs_Human0.90976075
92P300_19829295_ChIP-Seq_ESCs_Human0.90757454
93AR_20517297_ChIP-Seq_VCAP_Human0.90292272
94XRN2_22483619_ChIP-Seq_HELA_Human0.88144377
95ERA_21632823_ChIP-Seq_H3396_Human0.87066570
96STAT1_20625510_ChIP-Seq_HELA_Human0.86903285
97PCGF2_27294783_Chip-Seq_NPCs_Mouse0.85366461
98SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.85348189
99TDRD3_21172665_ChIP-Seq_MCF-7_Human0.85155319
100TCF4_22108803_ChIP-Seq_LS180_Human0.84867449

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.60313427
2MP0004142_abnormal_muscle_tone3.26950991
3MP0000569_abnormal_digit_pigmentation3.05612544
4MP0006292_abnormal_olfactory_placode2.89104177
5MP0002837_dystrophic_cardiac_calcinosis2.67477689
6MP0003186_abnormal_redox_activity2.64809869
7MP0003011_delayed_dark_adaptation2.60597188
8MP0002234_abnormal_pharynx_morphology2.37974040
9MP0001440_abnormal_grooming_behavior2.22015440
10MP0004145_abnormal_muscle_electrophysio2.12599479
11MP0003880_abnormal_central_pattern2.05678188
12MP0005423_abnormal_somatic_nervous2.03690598
13MP0001835_abnormal_antigen_presentation1.96027864
14MP0008789_abnormal_olfactory_epithelium1.90907249
15MP0001529_abnormal_vocalization1.79996159
16MP0003646_muscle_fatigue1.79270458
17MP0008877_abnormal_DNA_methylation1.74529646
18MP0002160_abnormal_reproductive_system1.73458223
19MP0005389_reproductive_system_phenotype1.72955526
20MP0004885_abnormal_endolymph1.70340180
21MP0001348_abnormal_lacrimal_gland1.66979765
22MP0002184_abnormal_innervation1.66207847
23MP0002163_abnormal_gland_morphology1.60586201
24MP0000049_abnormal_middle_ear1.57844960
25MP0002638_abnormal_pupillary_reflex1.57258467
26MP0001905_abnormal_dopamine_level1.57242235
27MP0005394_taste/olfaction_phenotype1.56102401
28MP0005499_abnormal_olfactory_system1.56102401
29MP0001986_abnormal_taste_sensitivity1.52379283
30MP0002272_abnormal_nervous_system1.47025233
31MP0001919_abnormal_reproductive_system1.45333308
32MP0009745_abnormal_behavioral_response1.42038247
33MP0006072_abnormal_retinal_apoptosis1.40196745
34MP0002734_abnormal_mechanical_nocicepti1.38391005
35MP0004147_increased_porphyrin_level1.37105079
36MP0002733_abnormal_thermal_nociception1.36736730
37MP0009764_decreased_sensitivity_to1.36135033
38MP0002102_abnormal_ear_morphology1.34843854
39MP0005551_abnormal_eye_electrophysiolog1.34764816
40MP0000778_abnormal_nervous_system1.32504050
41MP0002653_abnormal_ependyma_morphology1.32006653
42MP0010030_abnormal_orbit_morphology1.31909798
43MP0005671_abnormal_response_to1.31230674
44MP0003879_abnormal_hair_cell1.30031442
45MP0006276_abnormal_autonomic_nervous1.27694601
46MP0001968_abnormal_touch/_nociception1.27324794
47MP0002876_abnormal_thyroid_physiology1.27010889
48MP0001293_anophthalmia1.26936898
49MP0003890_abnormal_embryonic-extraembry1.26254302
50MP0001970_abnormal_pain_threshold1.24942744
51MP0000631_abnormal_neuroendocrine_gland1.17549987
52MP0008872_abnormal_physiological_respon1.17429525
53MP0004742_abnormal_vestibular_system1.17198452
54MP0000534_abnormal_ureter_morphology1.16173736
55MP0003787_abnormal_imprinting1.14086760
56MP0003878_abnormal_ear_physiology1.10608550
57MP0005377_hearing/vestibular/ear_phenot1.10608550
58MP0000685_abnormal_immune_system1.07847577
59MP0005195_abnormal_posterior_eye1.07766193
60MP0003283_abnormal_digestive_organ1.07397417
61MP0002067_abnormal_sensory_capabilities1.02554580
62MP0000955_abnormal_spinal_cord1.00344325
63MP0002752_abnormal_somatic_nervous0.99936766
64MP0000427_abnormal_hair_cycle0.99785172
65MP0002736_abnormal_nociception_after0.98327712
66MP0003567_abnormal_fetal_cardiomyocyte0.96347038
67MP0000750_abnormal_muscle_regeneration0.95676866
68MP0003635_abnormal_synaptic_transmissio0.95222515
69MP0001984_abnormal_olfaction0.94455455
70MP0001485_abnormal_pinna_reflex0.93532768
71MP0005387_immune_system_phenotype0.92344993
72MP0001790_abnormal_immune_system0.92344993
73MP0005646_abnormal_pituitary_gland0.90842737
74MP0005174_abnormal_tail_pigmentation0.90420035
75MP0000026_abnormal_inner_ear0.90262062
76MP0003123_paternal_imprinting0.89639628
77MP0002557_abnormal_social/conspecific_i0.89530942
78MP0002229_neurodegeneration0.88119997
79MP0008775_abnormal_heart_ventricle0.87750513
80MP0000470_abnormal_stomach_morphology0.86951427
81MP0004019_abnormal_vitamin_homeostasis0.86104020
82MP0003122_maternal_imprinting0.85163111
83MP0005379_endocrine/exocrine_gland_phen0.84803978
84MP0003638_abnormal_response/metabolism_0.82161134
85MP0002064_seizures0.81728214
86MP0003942_abnormal_urinary_system0.81333720
87MP0004924_abnormal_behavior0.81238370
88MP0005386_behavior/neurological_phenoty0.81238370
89MP0001286_abnormal_eye_development0.79642787
90MP0002572_abnormal_emotion/affect_behav0.79511576
91MP0001963_abnormal_hearing_physiology0.79145147
92MP0002882_abnormal_neuron_morphology0.78448099
93MP0005253_abnormal_eye_physiology0.77069477
94MP0009046_muscle_twitch0.75876011
95MP0003632_abnormal_nervous_system0.73369769
96MP0003121_genomic_imprinting0.73095269
97MP0001188_hyperpigmentation0.72794868
98MP0003137_abnormal_impulse_conducting0.72626426
99MP0001324_abnormal_eye_pigmentation0.72474599
100MP0001727_abnormal_embryo_implantation0.72370898

Predicted human phenotypes

RankGene SetZ-score
1Type II lissencephaly (HP:0007260)5.33530621
2Acute necrotizing encephalopathy (HP:0006965)4.75729726
3Abnormal mitochondria in muscle tissue (HP:0008316)4.23402997
4Progressive macrocephaly (HP:0004481)4.12305529
5Hepatocellular necrosis (HP:0001404)4.11659343
6Multiple enchondromatosis (HP:0005701)4.11475257
7Mitochondrial inheritance (HP:0001427)4.08730401
8Aplasia/Hypoplasia of the sacrum (HP:0008517)3.97375057
9Retinal dysplasia (HP:0007973)3.90338729
10Abnormality of cells of the erythroid lineage (HP:0012130)3.84707356
11Acute encephalopathy (HP:0006846)3.77769533
12Increased CSF lactate (HP:0002490)3.73577011
13Elevated erythrocyte sedimentation rate (HP:0003565)3.56103187
14Stomatitis (HP:0010280)3.41765145
15Hepatic necrosis (HP:0002605)3.32764937
16Respiratory insufficiency due to defective ciliary clearance (HP:0200073)3.23975003
17Increased IgM level (HP:0003496)3.16520717
18Cerebellar dysplasia (HP:0007033)3.09401085
19Mesomelia (HP:0003027)3.08348270
20Reticulocytopenia (HP:0001896)3.06032253
21Macrocytic anemia (HP:0001972)2.94290897
22Abnormal number of erythroid precursors (HP:0012131)2.91520708
23Increased hepatocellular lipid droplets (HP:0006565)2.86592551
24Myokymia (HP:0002411)2.85898852
25Molar tooth sign on MRI (HP:0002419)2.73038011
26Abnormality of midbrain morphology (HP:0002418)2.73038011
27Cerebral palsy (HP:0100021)2.70159333
28Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.58300589
29Anterior segment dysgenesis (HP:0007700)2.56788120
30Abnormality of the phalanges of the 5th finger (HP:0004213)2.55536598
31Pallor (HP:0000980)2.55251418
32Optic disc pallor (HP:0000543)2.52018581
333-Methylglutaconic aciduria (HP:0003535)2.49371422
34Absent rod-and cone-mediated responses on ERG (HP:0007688)2.46149053
35Lipid accumulation in hepatocytes (HP:0006561)2.45726985
36Leukodystrophy (HP:0002415)2.45221751
37Progressive cerebellar ataxia (HP:0002073)2.44939048
38Hypoplasia of the ulna (HP:0003022)2.42873022
39Cerebral edema (HP:0002181)2.41191320
40Short femoral neck (HP:0100864)2.38088012
41Congenital, generalized hypertrichosis (HP:0004540)2.34758144
42Parakeratosis (HP:0001036)2.34522442
43Renal Fanconi syndrome (HP:0001994)2.32337571
44Abolished electroretinogram (ERG) (HP:0000550)2.27819908
45Short tibia (HP:0005736)2.20803810
46Bifid tongue (HP:0010297)2.18104131
47Respiratory failure (HP:0002878)2.12712490
48Aplasia/Hypoplasia of the ulna (HP:0006495)2.12314255
49IgG deficiency (HP:0004315)2.09583311
50Aplasia/Hypoplasia of the spleen (HP:0010451)2.09038106
51Pancreatic cysts (HP:0001737)2.07933112
52Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)2.07753632
53Aplasia/Hypoplasia of the uvula (HP:0010293)2.07199315
54Short middle phalanx of the 5th finger (HP:0004220)2.06657632
55Aplasia/Hypoplasia of the tibia (HP:0005772)2.05786425
56Abnormality of DNA repair (HP:0003254)2.04449734
57Medial flaring of the eyebrow (HP:0010747)2.04107030
58Hypomagnesemia (HP:0002917)2.03611650
59Abnormal rod and cone electroretinograms (HP:0008323)2.02837835
60Stenosis of the external auditory canal (HP:0000402)2.02154083
61Severe muscular hypotonia (HP:0006829)2.00582121
62Rib fusion (HP:0000902)1.99757915
63Lissencephaly (HP:0001339)1.98610782
64Abnormality of magnesium homeostasis (HP:0004921)1.98358389
65Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.98233598
66Increased intramyocellular lipid droplets (HP:0012240)1.96936887
67Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.96110343
68Abnormality of the vitreous humor (HP:0004327)1.95814143
69Respiratory difficulties (HP:0002880)1.95062146
70Concave nail (HP:0001598)1.94890676
71Cleft eyelid (HP:0000625)1.94524195
72Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.93974490
73Congenital stationary night blindness (HP:0007642)1.92896218
74X-linked dominant inheritance (HP:0001423)1.91732419
75Symphalangism affecting the phalanges of the hand (HP:0009773)1.91406649
76Exertional dyspnea (HP:0002875)1.89892961
77Optic nerve hypoplasia (HP:0000609)1.89062401
78Septo-optic dysplasia (HP:0100842)1.88824141
79Abnormal hemoglobin (HP:0011902)1.86918049
80Radial bowing (HP:0002986)1.84548228
81Chronic bronchitis (HP:0004469)1.82848700
82Asplenia (HP:0001746)1.82442622
83Partial agenesis of the corpus callosum (HP:0001338)1.82047637
84Absent thumb (HP:0009777)1.81173762
85Lactic acidosis (HP:0003128)1.79246096
86Median cleft lip (HP:0000161)1.77791482
87Abnormality of renal resorption (HP:0011038)1.77730129
88Abnormal respiratory motile cilium physiology (HP:0012261)1.77671713
89Enlarged kidneys (HP:0000105)1.75867531
90Peritonitis (HP:0002586)1.75244316
91Hypoplasia of the uterus (HP:0000013)1.73931971
92Nephronophthisis (HP:0000090)1.73077444
93Cutaneous finger syndactyly (HP:0010554)1.72412994
94Abnormality of the pons (HP:0007361)1.71577783
95Thyroiditis (HP:0100646)1.69707729
96Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69043428
97Pendular nystagmus (HP:0012043)1.68652626
98Severe combined immunodeficiency (HP:0004430)1.67477140
99Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.66139481
100Growth hormone deficiency (HP:0000824)1.63964071

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K125.32607361
2MAP3K113.54569148
3DYRK23.40090808
4MAP4K22.93052074
5MAP3K132.59614377
6FRK2.57530184
7WNK42.34958349
8ADRBK22.15267198
9EPHA41.97699597
10PIK3CA1.92229523
11GRK11.91384433
12DYRK1B1.87693571
13NEK11.83153029
14MAP4K11.81034034
15TAOK31.78906451
16EPHB21.75474051
17BMPR1B1.64541440
18DAPK31.54304053
19CDK191.52773720
20TIE11.50858680
21TLK11.47984344
22OXSR11.47634653
23TYRO31.39395262
24MST41.32626937
25LRRK21.30909307
26PINK11.21795551
27ILK1.21738052
28STK161.20921503
29MYLK1.11496760
30NUAK11.10526983
31TGFBR11.10049476
32NME21.08446953
33STK391.04409563
34INSRR1.01699831
35MAP2K40.98213035
36PIM20.95442747
37IKBKB0.95036374
38MAP3K90.94898476
39ZAK0.92923876
40CAMK2D0.88782743
41NME10.88187846
42NTRK20.88179153
43TXK0.84139896
44PDK20.80075019
45CDK80.79499187
46BCKDK0.79020424
47PHKG10.78834687
48PHKG20.78834687
49KSR10.78367335
50DAPK20.78314857
51MAP3K40.76520657
52WNK10.72916027
53CAMK2B0.72534671
54PAK30.71184432
55CSF1R0.69668814
56CHUK0.66673469
57BTK0.65566981
58PRKACA0.65438128
59CSNK1G30.64628270
60ABL20.64092863
61PNCK0.63893590
62TEC0.63748417
63PKN10.62071337
64MKNK10.61785075
65AURKB0.60862619
66CSNK1G20.59782121
67RPS6KA60.59703237
68HIPK20.59533785
69FLT30.59311461
70PIM10.58769491
71PLK20.58650857
72CAMK2G0.58268708
73PASK0.57209069
74PRKCQ0.55582304
75CAMK10.55455564
76CAMK2A0.54873310
77OBSCN0.52897324
78ITK0.52815896
79ADRBK10.52436300
80CSNK1A1L0.52102218
81DAPK10.51655640
82MKNK20.51087296
83NTRK30.49230477
84PRKCG0.48727290
85CSNK2A20.48343133
86TAOK20.45408613
87ATR0.45253508
88DYRK30.45013331
89CAMK40.44987533
90LCK0.43708034
91RPS6KC10.43379144
92RPS6KL10.43379144
93AURKA0.41604775
94SGK10.40900237
95PRKCE0.40797916
96PRKCD0.40349501
97RPS6KA50.39649577
98WNK30.39301744
99PRKCA0.39237350
100CSNK1A10.39009687

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.99942832
2Oxidative phosphorylation_Homo sapiens_hsa001904.23343891
3Parkinsons disease_Homo sapiens_hsa050123.82688664
4Asthma_Homo sapiens_hsa053103.69234435
5Protein export_Homo sapiens_hsa030603.62888653
6Cardiac muscle contraction_Homo sapiens_hsa042603.09135228
7Allograft rejection_Homo sapiens_hsa053303.03328524
8Autoimmune thyroid disease_Homo sapiens_hsa053202.85666676
9Alzheimers disease_Homo sapiens_hsa050102.66696103
10Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.61419943
11Intestinal immune network for IgA production_Homo sapiens_hsa046722.58957233
12Huntingtons disease_Homo sapiens_hsa050162.40992535
13RNA polymerase_Homo sapiens_hsa030202.26647708
14Graft-versus-host disease_Homo sapiens_hsa053322.24424802
15Type I diabetes mellitus_Homo sapiens_hsa049402.22530798
16Linoleic acid metabolism_Homo sapiens_hsa005911.60280753
17Proteasome_Homo sapiens_hsa030501.59567295
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.50283933
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.44259654
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31282910
21Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.30618734
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.28924348
23RNA degradation_Homo sapiens_hsa030181.27483348
24Viral myocarditis_Homo sapiens_hsa054161.27394733
25Fatty acid elongation_Homo sapiens_hsa000621.26777600
26Phototransduction_Homo sapiens_hsa047441.16996811
27alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.11311595
28Tryptophan metabolism_Homo sapiens_hsa003801.10075382
29Basal transcription factors_Homo sapiens_hsa030221.08915832
30Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.08448286
31Rheumatoid arthritis_Homo sapiens_hsa053231.07887127
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.02967841
33Olfactory transduction_Homo sapiens_hsa047400.99961899
34Chemical carcinogenesis_Homo sapiens_hsa052040.95270431
35Caffeine metabolism_Homo sapiens_hsa002320.93793877
36Nucleotide excision repair_Homo sapiens_hsa034200.91728237
37Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.81456965
38Antigen processing and presentation_Homo sapiens_hsa046120.80863895
39Primary immunodeficiency_Homo sapiens_hsa053400.76681008
40Systemic lupus erythematosus_Homo sapiens_hsa053220.74665811
41Pyrimidine metabolism_Homo sapiens_hsa002400.73921916
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73691470
43Glutathione metabolism_Homo sapiens_hsa004800.73002983
44Morphine addiction_Homo sapiens_hsa050320.72281976
45Homologous recombination_Homo sapiens_hsa034400.70519210
46Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.70018300
47Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.69701447
48RNA transport_Homo sapiens_hsa030130.69628424
49GABAergic synapse_Homo sapiens_hsa047270.68543006
50Serotonergic synapse_Homo sapiens_hsa047260.68425320
51Staphylococcus aureus infection_Homo sapiens_hsa051500.67718874
52Nicotine addiction_Homo sapiens_hsa050330.65861974
53Nitrogen metabolism_Homo sapiens_hsa009100.65345952
54Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64892716
55Collecting duct acid secretion_Homo sapiens_hsa049660.64116079
56Mismatch repair_Homo sapiens_hsa034300.57494884
57Regulation of autophagy_Homo sapiens_hsa041400.55708338
58African trypanosomiasis_Homo sapiens_hsa051430.53499535
59Arachidonic acid metabolism_Homo sapiens_hsa005900.51349070
60Spliceosome_Homo sapiens_hsa030400.48954176
61Ether lipid metabolism_Homo sapiens_hsa005650.47801534
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47174961
63Metabolic pathways_Homo sapiens_hsa011000.44398911
64Folate biosynthesis_Homo sapiens_hsa007900.44058714
65Purine metabolism_Homo sapiens_hsa002300.43466609
66Circadian entrainment_Homo sapiens_hsa047130.43258132
67Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.42845383
68Retinol metabolism_Homo sapiens_hsa008300.42147698
69Glutamatergic synapse_Homo sapiens_hsa047240.40688700
70Butanoate metabolism_Homo sapiens_hsa006500.40560456
71Vitamin B6 metabolism_Homo sapiens_hsa007500.40445023
72Insulin secretion_Homo sapiens_hsa049110.39441801
73Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39103321
74Peroxisome_Homo sapiens_hsa041460.37549556
75Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.37280957
76p53 signaling pathway_Homo sapiens_hsa041150.37037992
77Fanconi anemia pathway_Homo sapiens_hsa034600.36537766
78Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.35435989
79Steroid hormone biosynthesis_Homo sapiens_hsa001400.35264650
80Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.34133714
81Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.32871597
82Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.30570935
83Type II diabetes mellitus_Homo sapiens_hsa049300.30216957
84Taste transduction_Homo sapiens_hsa047420.28956799
85Cholinergic synapse_Homo sapiens_hsa047250.28471865
86Cysteine and methionine metabolism_Homo sapiens_hsa002700.27620997
87Epstein-Barr virus infection_Homo sapiens_hsa051690.26414085
88Salivary secretion_Homo sapiens_hsa049700.26003041
89Leishmaniasis_Homo sapiens_hsa051400.23641985
90Steroid biosynthesis_Homo sapiens_hsa001000.22605416
91Ovarian steroidogenesis_Homo sapiens_hsa049130.19877493
92Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.19602350
93Phagosome_Homo sapiens_hsa041450.18443689
94Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.17786302
95DNA replication_Homo sapiens_hsa030300.16797398
96NF-kappa B signaling pathway_Homo sapiens_hsa040640.16476736
97Fat digestion and absorption_Homo sapiens_hsa049750.15333750
98Ras signaling pathway_Homo sapiens_hsa040140.15218880
99Pentose and glucuronate interconversions_Homo sapiens_hsa000400.14313895
100Starch and sucrose metabolism_Homo sapiens_hsa005000.13503573

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