RPS23P6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1serotonin metabolic process (GO:0042428)8.00350019
2regulation of Golgi to plasma membrane protein transport (GO:0042996)7.28794962
3primary amino compound metabolic process (GO:1901160)7.18180260
4activated T cell proliferation (GO:0050798)6.66550137
5positive regulation of type I interferon-mediated signaling pathway (GO:0060340)6.58974427
6antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)6.00702849
7regulation of G0 to G1 transition (GO:0070316)5.45874387
8intra-S DNA damage checkpoint (GO:0031573)5.33706853
9antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.26265399
10regulation of transforming growth factor beta2 production (GO:0032909)5.12122385
11indolalkylamine metabolic process (GO:0006586)5.08352462
12epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)4.91772159
13indole-containing compound metabolic process (GO:0042430)4.90098010
14spliceosomal tri-snRNP complex assembly (GO:0000244)4.89618167
15response to interferon-beta (GO:0035456)4.76345839
16purinergic nucleotide receptor signaling pathway (GO:0035590)4.52946284
17positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021104.48477515
18mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)4.48477515
19snRNA transcription (GO:0009301)4.36848008
20negative regulation of establishment of protein localization to plasma membrane (GO:0090005)4.35497653
21positive regulation of antigen processing and presentation (GO:0002579)4.28598916
22regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway (GO:0039531)4.26572271
23L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.23693007
24regulation of RIG-I signaling pathway (GO:0039535)4.20687436
25antigen processing and presentation of endogenous antigen (GO:0019883)4.19245708
26phosphatidylserine acyl-chain remodeling (GO:0036150)4.14073933
27G-protein coupled purinergic nucleotide receptor signaling pathway (GO:0035589)4.13611579
28replication fork processing (GO:0031297)3.87589724
29mannose metabolic process (GO:0006013)3.85732601
30regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.84711414
31positive regulation of organelle assembly (GO:1902117)3.79613918
32macrophage differentiation (GO:0030225)3.69745485
33negative regulation of viral genome replication (GO:0045071)3.64889913
34photoreceptor cell maintenance (GO:0045494)3.62502516
35regulation of type I interferon-mediated signaling pathway (GO:0060338)3.60909092
36regulation of catecholamine metabolic process (GO:0042069)3.58602382
37regulation of dopamine metabolic process (GO:0042053)3.58602382
38amino acid salvage (GO:0043102)3.55043052
39L-methionine salvage (GO:0071267)3.55043052
40L-methionine biosynthetic process (GO:0071265)3.55043052
41regulation of dopamine uptake involved in synaptic transmission (GO:0051584)3.51760169
42regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)3.51760169
43peristalsis (GO:0030432)3.50150907
44negative regulation of chemokine production (GO:0032682)3.46280925
45aromatic amino acid family metabolic process (GO:0009072)3.45211776
46phosphatidylethanolamine biosynthetic process (GO:0006646)3.45106365
47behavioral response to cocaine (GO:0048148)3.42357515
48DNA methylation involved in gamete generation (GO:0043046)3.37337002
49RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.36477313
50UDP-N-acetylglucosamine metabolic process (GO:0006047)3.35107786
51keratinocyte development (GO:0003334)3.32830743
52positive regulation of mRNA catabolic process (GO:0061014)3.32626346
53positive regulation of mitochondrial membrane permeability (GO:0035794)3.32367723
54vesicle fusion (GO:0006906)3.27394583
55phosphatidylethanolamine metabolic process (GO:0046337)3.21180775
56epithelial cilium movement (GO:0003351)3.16839504
57L-alpha-amino acid transmembrane transport (GO:1902475)3.14832059
58phosphatidylethanolamine acyl-chain remodeling (GO:0036152)3.12319133
59positive regulation of transforming growth factor beta production (GO:0071636)3.11955576
60positive regulation of interferon-beta production (GO:0032728)3.09810663
61regulation of dendritic cell antigen processing and presentation (GO:0002604)3.08229410
62G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.04915982
63kynurenine metabolic process (GO:0070189)3.04780932
64positive regulation of interferon-alpha production (GO:0032727)3.02296905
65regulation of antigen processing and presentation (GO:0002577)3.00394997
66antigen processing and presentation via MHC class Ib (GO:0002475)3.00037964
67regulation of translation in response to stress (GO:0043555)2.97901015
68regulation of interferon-alpha production (GO:0032647)2.96205385
69indole-containing compound catabolic process (GO:0042436)2.95059729
70indolalkylamine catabolic process (GO:0046218)2.95059729
71tryptophan catabolic process (GO:0006569)2.95059729
72regulation of interferon-beta production (GO:0032648)2.93212282
73positive regulation of gluconeogenesis (GO:0045722)2.92248618
74regulation of neurotransmitter uptake (GO:0051580)2.91376634
75sulfate transmembrane transport (GO:1902358)2.90810007
76purinergic receptor signaling pathway (GO:0035587)2.87656189
77ribosome assembly (GO:0042255)2.85666022
78eye photoreceptor cell differentiation (GO:0001754)2.79614781
79photoreceptor cell differentiation (GO:0046530)2.79614781
80phosphatidylserine metabolic process (GO:0006658)2.79185881
81phosphatidylcholine acyl-chain remodeling (GO:0036151)2.78223232
82DNA methylation (GO:0006306)2.76941116
83DNA alkylation (GO:0006305)2.76941116
84cytokine biosynthetic process (GO:0042089)2.75967755
85response to pheromone (GO:0019236)2.75523083
86negative regulation of protein localization to plasma membrane (GO:1903077)2.74169897
87nodal signaling pathway (GO:0038092)2.73258265
88musculoskeletal movement (GO:0050881)2.72643790
89multicellular organismal movement (GO:0050879)2.72643790
90maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.71556207
91cellular response to electrical stimulus (GO:0071257)2.68584139
92regulation of histone deacetylation (GO:0031063)2.66826316
93positive regulation of establishment of protein localization to plasma membrane (GO:0090004)2.66566701
94aromatic amino acid family catabolic process (GO:0009074)2.66485671
95regulation of mRNA catabolic process (GO:0061013)2.65810400
96methionine biosynthetic process (GO:0009086)2.64330563
97positive regulation of developmental pigmentation (GO:0048087)2.63025041
98cAMP catabolic process (GO:0006198)2.62633201
99cellular response to arsenic-containing substance (GO:0071243)2.62394314
100lactate metabolic process (GO:0006089)11.0705983

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse6.13713671
2RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.83989664
3IRF8_22096565_ChIP-ChIP_GC-B_Human3.91795808
4GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.72821493
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.28801689
6IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.26490165
7GBX2_23144817_ChIP-Seq_PC3_Human3.11378827
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.06895086
9IGF1R_20145208_ChIP-Seq_DFB_Human2.74308289
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.47692622
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.44252739
12VDR_22108803_ChIP-Seq_LS180_Human1.90424735
13IRF8_21731497_ChIP-ChIP_J774_Mouse1.84923975
14ZNF274_21170338_ChIP-Seq_K562_Hela1.83514190
15CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.76739468
16GATA1_26923725_Chip-Seq_HPCs_Mouse1.66130240
17SALL1_21062744_ChIP-ChIP_HESCs_Human1.61094326
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.59435527
19RAC3_21632823_ChIP-Seq_H3396_Human1.59175945
20HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.56606464
21TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51534007
22POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.51534007
23DROSHA_22980978_ChIP-Seq_HELA_Human1.49855682
24EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.49136035
25NOTCH1_21737748_ChIP-Seq_TLL_Human1.43724626
26PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.42278588
27LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.42006021
28PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.39461117
29TCF4_22108803_ChIP-Seq_LS180_Human1.30761027
30VDR_23849224_ChIP-Seq_CD4+_Human1.29445885
31PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.27854718
32SMRT_27268052_Chip-Seq_Bcells_Human1.26986088
33PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.25872422
34SMAD_19615063_ChIP-ChIP_OVARY_Human1.25557026
35FOXA1_27270436_Chip-Seq_PROSTATE_Human1.23596441
36FOXA1_25329375_ChIP-Seq_VCAP_Human1.23596441
37PCGF2_27294783_Chip-Seq_NPCs_Mouse1.23224724
38GATA1_22025678_ChIP-Seq_K562_Human1.23033073
39VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18076943
40ETS1_20019798_ChIP-Seq_JURKAT_Human1.17949489
41JUN_21703547_ChIP-Seq_K562_Human1.17894783
42FUS_26573619_Chip-Seq_HEK293_Human1.16906655
43CEBPB_22108803_ChIP-Seq_LS180_Human1.14276552
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.12567568
45GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.12479402
46EGR1_23403033_ChIP-Seq_LIVER_Mouse1.12277614
47CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12199070
48LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.11414776
49UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11148536
50CBX2_27304074_Chip-Seq_ESCs_Mouse1.09939402
51WDR5_24793694_ChIP-Seq_LNCAP_Human1.09272937
52GABP_17652178_ChIP-ChIP_JURKAT_Human1.08492959
53SUZ12_27294783_Chip-Seq_NPCs_Mouse1.06730240
54PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06517839
55BCAT_22108803_ChIP-Seq_LS180_Human1.05537093
56NANOG_20526341_ChIP-Seq_ESCs_Human1.05476639
57NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05107905
58AR_20517297_ChIP-Seq_VCAP_Human1.04469981
59MYC_18940864_ChIP-ChIP_HL60_Human1.02673855
60SUZ12_18555785_Chip-Seq_ESCs_Mouse1.02376953
61HOXB7_26014856_ChIP-Seq_BT474_Human1.02187796
62PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.02118549
63BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.01321749
64FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.01244144
65ZFP57_27257070_Chip-Seq_ESCs_Mouse1.01128098
66NFE2_27457419_Chip-Seq_LIVER_Mouse1.00461380
67GATA3_26560356_Chip-Seq_TH2_Human1.00119567
68PRDM14_20953172_ChIP-Seq_ESCs_Human0.99725653
69TP53_22573176_ChIP-Seq_HFKS_Human0.99337503
70ER_23166858_ChIP-Seq_MCF-7_Human0.98801257
71PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98244571
72NCOR_22424771_ChIP-Seq_293T_Human0.97199766
73STAT3_23295773_ChIP-Seq_U87_Human0.96925918
74MYB_26560356_Chip-Seq_TH2_Human0.96394868
75AUTS2_25519132_ChIP-Seq_293T-REX_Human0.96021027
76RUNX1_27457419_Chip-Seq_LIVER_Mouse0.95477125
77PKCTHETA_26484144_Chip-Seq_BREAST_Human0.95429585
78EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.94746395
79TCF4_23295773_ChIP-Seq_U87_Human0.93269554
80OCT4_20526341_ChIP-Seq_ESCs_Human0.93192727
81EZH2_27294783_Chip-Seq_NPCs_Mouse0.91875884
82STAT3_1855785_ChIP-Seq_MESCs_Mouse0.91181367
83ERA_21632823_ChIP-Seq_H3396_Human0.90510670
84EWS_26573619_Chip-Seq_HEK293_Human0.90025310
85FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89895945
86POU3F2_20337985_ChIP-ChIP_501MEL_Human0.89459139
87CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88265423
88STAT4_19710469_ChIP-ChIP_TH1__Mouse0.87788418
89P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.86855406
90STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.86401078
91MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.86038962
92P300_18555785_Chip-Seq_ESCs_Mouse0.85471303
93JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.85253694
94NANOG_18555785_Chip-Seq_ESCs_Mouse0.84116473
95VDR_24787735_ChIP-Seq_THP-1_Human0.83805202
96RXR_22108803_ChIP-Seq_LS180_Human0.83617275
97ELK1_19687146_ChIP-ChIP_HELA_Human0.82924366
98BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82295671
99GATA3_21867929_ChIP-Seq_TH1_Mouse0.82033904
100SRF_21415370_ChIP-Seq_HL-1_Mouse0.81819229

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting6.41829783
2MP0002837_dystrophic_cardiac_calcinosis3.79612987
3MP0008877_abnormal_DNA_methylation2.96965266
4MP0001835_abnormal_antigen_presentation2.83498702
5MP0004885_abnormal_endolymph2.72134611
6MP0006276_abnormal_autonomic_nervous2.65920084
7MP0006072_abnormal_retinal_apoptosis2.46221715
8MP0001501_abnormal_sleep_pattern2.36046895
9MP0003121_genomic_imprinting2.09918297
10MP0003693_abnormal_embryo_hatching2.05648468
11MP0001764_abnormal_homeostasis2.02995510
12MP0009785_altered_susceptibility_to1.95403995
13MP0003195_calcinosis1.92058582
14MP0005551_abnormal_eye_electrophysiolog1.84452541
15MP0002653_abnormal_ependyma_morphology1.78333345
16MP0008789_abnormal_olfactory_epithelium1.77821542
17MP0009780_abnormal_chondrocyte_physiolo1.73908362
18MP0005389_reproductive_system_phenotype1.72765634
19MP0005253_abnormal_eye_physiology1.67985515
20MP0002938_white_spotting1.67109425
21MP0002638_abnormal_pupillary_reflex1.60154494
22MP0005671_abnormal_response_to1.57796157
23MP0003763_abnormal_thymus_physiology1.55779456
24MP0006054_spinal_hemorrhage1.52336647
25MP0002693_abnormal_pancreas_physiology1.50489118
26MP0001919_abnormal_reproductive_system1.49608765
27MP0004133_heterotaxia1.46328060
28MP0005646_abnormal_pituitary_gland1.45394819
29MP0002876_abnormal_thyroid_physiology1.40795454
30MP0005410_abnormal_fertilization1.36641355
31MP0005647_abnormal_sex_gland1.35260138
32MP0002723_abnormal_immune_serum1.34494796
33MP0006292_abnormal_olfactory_placode1.33699796
34MP0005377_hearing/vestibular/ear_phenot1.33281794
35MP0003878_abnormal_ear_physiology1.33281794
36MP0005408_hypopigmentation1.32106365
37MP0001968_abnormal_touch/_nociception1.29863122
38MP0005075_abnormal_melanosome_morpholog1.29684730
39MP0010386_abnormal_urinary_bladder1.29518446
40MP0001800_abnormal_humoral_immune1.26202625
41MP0009115_abnormal_fat_cell1.25710147
42MP0001790_abnormal_immune_system1.24379731
43MP0005387_immune_system_phenotype1.24379731
44MP0008057_abnormal_DNA_replication1.23615755
45MP0005394_taste/olfaction_phenotype1.20570480
46MP0005499_abnormal_olfactory_system1.20570480
47MP0002909_abnormal_adrenal_gland1.19136005
48MP0005451_abnormal_body_composition1.18895710
49MP0002095_abnormal_skin_pigmentation1.18712658
50MP0002160_abnormal_reproductive_system1.16142966
51MP0002064_seizures1.15923597
52MP0002557_abnormal_social/conspecific_i1.15836219
53MP0001851_eye_inflammation1.13854175
54MP0004147_increased_porphyrin_level1.11597086
55MP0000427_abnormal_hair_cycle1.08741386
56MP0002736_abnormal_nociception_after1.07780779
57MP0002420_abnormal_adaptive_immunity1.07237877
58MP0005332_abnormal_amino_acid1.04523686
59MP0001819_abnormal_immune_cell1.01584557
60MP0005195_abnormal_posterior_eye1.01396759
61MP0000372_irregular_coat_pigmentation1.00123148
62MP0004924_abnormal_behavior0.99894704
63MP0005386_behavior/neurological_phenoty0.99894704
64MP0002254_reproductive_system_inflammat0.99779667
65MP0005025_abnormal_response_to0.98985949
66MP0004019_abnormal_vitamin_homeostasis0.98849259
67MP0009745_abnormal_behavioral_response0.98685938
68MP0001324_abnormal_eye_pigmentation0.97889348
69MP0000015_abnormal_ear_pigmentation0.96278432
70MP0008469_abnormal_protein_level0.95581785
71MP0002078_abnormal_glucose_homeostasis0.95556770
72MP0000689_abnormal_spleen_morphology0.95010683
73MP0002452_abnormal_antigen_presenting0.93630020
74MP0001963_abnormal_hearing_physiology0.93394155
75MP0005448_abnormal_energy_balance0.92067221
76MP0001485_abnormal_pinna_reflex0.91918469
77MP0002933_joint_inflammation0.90872470
78MP0005670_abnormal_white_adipose0.89948970
79MP0002572_abnormal_emotion/affect_behav0.89429993
80MP0001944_abnormal_pancreas_morphology0.88732214
81MP0001970_abnormal_pain_threshold0.88304743
82MP0001191_abnormal_skin_condition0.87319342
83MP0000230_abnormal_systemic_arterial0.87215868
84MP0000470_abnormal_stomach_morphology0.85458114
85MP0009379_abnormal_foot_pigmentation0.85229292
86MP0010329_abnormal_lipoprotein_level0.85124477
87MP0001905_abnormal_dopamine_level0.83309659
88MP0002148_abnormal_hypersensitivity_rea0.82783112
89MP0005174_abnormal_tail_pigmentation0.82708737
90MP0002234_abnormal_pharynx_morphology0.82260450
91MP0002075_abnormal_coat/hair_pigmentati0.81671799
92MP0003698_abnormal_male_reproductive0.79560970
93MP0000858_altered_metastatic_potential0.78472220
94MP0002419_abnormal_innate_immunity0.78012770
95MP0009046_muscle_twitch0.77861936
96MP0010155_abnormal_intestine_physiology0.77308236
97MP0002398_abnormal_bone_marrow0.77023560
98MP0001873_stomach_inflammation0.76965137
99MP0000371_diluted_coat_color0.76578386
100MP0002229_neurodegeneration0.76079565

Predicted human phenotypes

RankGene SetZ-score
1Absent/shortened dynein arms (HP:0200106)4.32024458
2Dynein arm defect of respiratory motile cilia (HP:0012255)4.32024458
3Double outlet right ventricle (HP:0001719)3.99039662
4Congenital malformation of the right heart (HP:0011723)3.99039662
5Chronic sinusitis (HP:0011109)3.94648902
6Hepatoblastoma (HP:0002884)3.46188540
7Chronic otitis media (HP:0000389)3.41722429
8Volvulus (HP:0002580)3.34512877
9Severe muscular hypotonia (HP:0006829)3.26705068
10Hypochromic microcytic anemia (HP:0004840)3.24789375
11Tetany (HP:0001281)3.17737477
12Dialeptic seizures (HP:0011146)3.15815770
13IgG deficiency (HP:0004315)3.04574969
14Gout (HP:0001997)3.02769758
15Abnormal respiratory epithelium morphology (HP:0012253)2.94669679
16Abnormal respiratory motile cilium morphology (HP:0005938)2.94669679
17Abnormal ciliary motility (HP:0012262)2.89870537
18Abnormality of the renal collecting system (HP:0004742)2.87713627
19Pancreatic fibrosis (HP:0100732)2.84230690
20Pancreatic cysts (HP:0001737)2.78163223
21Panhypogammaglobulinemia (HP:0003139)2.71438172
22Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.70717189
23Abnormal hemoglobin (HP:0011902)2.70597608
24Duplicated collecting system (HP:0000081)2.69393139
25Chromosomal breakage induced by crosslinking agents (HP:0003221)2.67334544
26Metaphyseal dysplasia (HP:0100255)2.63881162
27Thyroiditis (HP:0100646)2.58507158
28Absence seizures (HP:0002121)2.58452893
29Limb hypertonia (HP:0002509)2.56692820
30Hematochezia (HP:0002573)2.51941072
31Abnormality of the renal cortex (HP:0011035)2.49478369
32Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.48175671
33Focal seizures (HP:0007359)2.43597551
34Agammaglobulinemia (HP:0004432)2.40715691
35Progressive inability to walk (HP:0002505)2.39762015
36Chromsome breakage (HP:0040012)2.37182555
37Colitis (HP:0002583)2.33304327
38Increased neuronal autofluorescent lipopigment (HP:0002074)2.33249603
39Severe combined immunodeficiency (HP:0004430)2.33090959
40Enlarged kidneys (HP:0000105)2.32273974
41Nasal polyposis (HP:0100582)2.31475846
42Medial flaring of the eyebrow (HP:0010747)2.29122148
43Tubular atrophy (HP:0000092)2.28484358
44Hypochromic anemia (HP:0001931)2.22190553
45Recurrent cutaneous fungal infections (HP:0011370)2.22019551
46Chronic mucocutaneous candidiasis (HP:0002728)2.22019551
47Focal motor seizures (HP:0011153)2.21421364
48Glucose intolerance (HP:0000833)2.20725330
49Hypoproteinemia (HP:0003075)2.17578568
50Intestinal atresia (HP:0011100)2.16874440
51Drooling (HP:0002307)2.14370438
52Increased hepatocellular lipid droplets (HP:0006565)2.11229789
53Xanthomatosis (HP:0000991)2.10216719
54Ketosis (HP:0001946)2.09254835
55Coxa vara (HP:0002812)2.08553082
56Albinism (HP:0001022)2.06650276
57Clumsiness (HP:0002312)2.04785327
58Congenital sensorineural hearing impairment (HP:0008527)2.04664424
59Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.01326272
60Brushfield spots (HP:0001088)2.00926634
61Excessive salivation (HP:0003781)1.99613499
62Cerebral hypomyelination (HP:0006808)1.98821533
63Absent frontal sinuses (HP:0002688)1.98573584
64Microcytic anemia (HP:0001935)1.98194570
65Abnormality of the nasal mucosa (HP:0000433)1.97012048
66Aplasia/Hypoplasia of the uvula (HP:0010293)1.93692730
67Renal Fanconi syndrome (HP:0001994)1.92888505
68Recurrent bronchitis (HP:0002837)1.92689040
69Hypoplasia of the thymus (HP:0000778)1.92224251
70Microtia (HP:0008551)1.91103812
71Recurrent sinusitis (HP:0011108)1.90673970
72Abnormal drinking behavior (HP:0030082)1.89758729
73Polydipsia (HP:0001959)1.89758729
74Protruding tongue (HP:0010808)1.89008964
75Abnormality of renal resorption (HP:0011038)1.88093505
76Severe visual impairment (HP:0001141)1.87966308
77Decreased circulating renin level (HP:0003351)1.85314788
78Encephalitis (HP:0002383)1.83836047
79Hyperkalemia (HP:0002153)1.83644526
80Increased cerebral lipofuscin (HP:0011813)1.82676525
81Exotropia (HP:0000577)1.82484449
82Metabolic acidosis (HP:0001942)1.80357730
83Congenital stationary night blindness (HP:0007642)1.79876173
84Pancytopenia (HP:0001876)1.78518800
85Enlarged epiphyses (HP:0010580)1.77854707
86Abnormality of B cell number (HP:0010975)1.74475091
87Abnormal respiratory motile cilium physiology (HP:0012261)1.74404134
88Abnormality of the nasal septum (HP:0000419)1.74015812
89Reticulocytopenia (HP:0001896)1.73949030
90Poor coordination (HP:0002370)1.72963017
91Neutropenia (HP:0001875)1.72552186
92Delayed puberty (HP:0000823)1.70625180
93Shawl scrotum (HP:0000049)1.70022634
94Abnormality of pyrimidine metabolism (HP:0004353)1.69471184
95Wide intermamillary distance (HP:0006610)1.68364894
96Retinitis pigmentosa (HP:0000510)1.67918060
97Aplasia/Hypoplasia of the spleen (HP:0010451)1.67699436
98Congenital primary aphakia (HP:0007707)1.67275026
99Increased IgE level (HP:0003212)1.65190037
100Combined immunodeficiency (HP:0005387)1.64377369

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ACVR1B9.23743384
2RIPK14.23318773
3MST44.17244709
4VRK13.82905966
5FRK2.23814292
6TEC2.04172953
7HIPK22.01480842
8JAK11.82270398
9TYK21.73911529
10NLK1.73643271
11MAP2K21.67021314
12MAP2K61.65194242
13MAP4K21.55463513
14FES1.54109860
15TAOK31.54105706
16IRAK11.51559117
17ADRBK21.48365981
18SCYL21.46107332
19PRKCI1.44645760
20TYRO31.41724661
21PLK31.37150038
22MARK31.30979667
23PKN21.28440390
24PRKCE1.25554587
25TXK1.23159277
26ZAK1.20929139
27FLT31.17470351
28JAK31.15239576
29OXSR11.10409723
30TNIK1.08040961
31PIK3CA1.02583468
32TNK21.01749515
33TRIM281.00814135
34NUAK11.00252369
35WNK30.98330616
36STK30.98296455
37KIT0.98249799
38GRK10.95533745
39TGFBR20.93243115
40MAPK130.92917003
41CLK10.91270970
42PLK20.91030083
43ITK0.90919799
44PHKG20.84699203
45PHKG10.84699203
46PIM10.83630302
47IRAK30.82670845
48TRPM70.80245759
49CDK190.78746065
50IKBKE0.76299377
51BTK0.75326256
52AURKB0.74567428
53MAPK70.73547050
54CDK80.70215867
55MELK0.69177013
56MKNK20.64926179
57PRKCH0.60241718
58TLK10.59412872
59MAP3K20.57812365
60PDK20.55886551
61STK100.55878757
62ERBB30.51823335
63RPS6KA50.50330741
64PRKG10.46804550
65HCK0.45693550
66PRKCQ0.44588492
67WNK40.44309990
68SRPK10.43401423
69ICK0.42192356
70CSNK1D0.41664968
71IKBKB0.41429183
72TIE10.39527975
73PTK2B0.38318964
74PRKACA0.36474239
75NTRK30.35488161
76STK390.34472983
77STK110.34386929
78LATS10.34251925
79MKNK10.34001582
80INSRR0.33996759
81DYRK1B0.33313857
82CDK30.32558429
83BMX0.32265398
84IRAK40.32022900
85PRKCG0.31628659
86DYRK1A0.30632051
87PRKCA0.30550880
88DYRK20.29700774
89BMPR20.28008331
90BCKDK0.27301072
91PRKACG0.27268087
92LYN0.26945195
93MAP4K10.26903714
94LCK0.26811153
95PRKCZ0.26372005
96DAPK20.26068279
97CSNK2A10.24971797
98TBK10.23387911
99ADRBK10.23025751
100ABL10.22758549

Predicted pathways (KEGG)

RankGene SetZ-score
1Homologous recombination_Homo sapiens_hsa034404.31256959
2Selenocompound metabolism_Homo sapiens_hsa004504.10625497
3Primary immunodeficiency_Homo sapiens_hsa053403.46012615
4Mismatch repair_Homo sapiens_hsa034303.18699738
5Tryptophan metabolism_Homo sapiens_hsa003803.06472082
6SNARE interactions in vesicular transport_Homo sapiens_hsa041302.91125496
7Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.66449388
8Basal transcription factors_Homo sapiens_hsa030222.64566049
9Fanconi anemia pathway_Homo sapiens_hsa034602.49135059
10Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002502.28269210
11Non-homologous end-joining_Homo sapiens_hsa034502.17106515
12Maturity onset diabetes of the young_Homo sapiens_hsa049502.09641583
13Nucleotide excision repair_Homo sapiens_hsa034202.00115084
14Cysteine and methionine metabolism_Homo sapiens_hsa002701.99100173
15Fatty acid elongation_Homo sapiens_hsa000621.92618748
16One carbon pool by folate_Homo sapiens_hsa006701.84410943
17Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.79901239
18Collecting duct acid secretion_Homo sapiens_hsa049661.79182356
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.66464373
20Propanoate metabolism_Homo sapiens_hsa006401.54709195
21Oxidative phosphorylation_Homo sapiens_hsa001901.51041898
22Peroxisome_Homo sapiens_hsa041461.48937024
23Glycerophospholipid metabolism_Homo sapiens_hsa005641.44983638
24Sulfur relay system_Homo sapiens_hsa041221.41096013
25RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.25175299
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.21311571
27Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12898539
28Olfactory transduction_Homo sapiens_hsa047401.11794282
29Butanoate metabolism_Homo sapiens_hsa006501.06751446
30Glycerolipid metabolism_Homo sapiens_hsa005611.05689141
31Glucagon signaling pathway_Homo sapiens_hsa049221.05459144
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.05166032
33Dorso-ventral axis formation_Homo sapiens_hsa043201.03495403
34Fatty acid metabolism_Homo sapiens_hsa012120.97786602
35Graft-versus-host disease_Homo sapiens_hsa053320.97323386
36Antigen processing and presentation_Homo sapiens_hsa046120.94941378
37Insulin secretion_Homo sapiens_hsa049110.92827983
38Intestinal immune network for IgA production_Homo sapiens_hsa046720.88381691
39DNA replication_Homo sapiens_hsa030300.86463752
40RNA degradation_Homo sapiens_hsa030180.85644786
41Taste transduction_Homo sapiens_hsa047420.85616788
42Thyroid hormone synthesis_Homo sapiens_hsa049180.84991524
43Phototransduction_Homo sapiens_hsa047440.82382513
44ABC transporters_Homo sapiens_hsa020100.81728756
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78591633
46Pyruvate metabolism_Homo sapiens_hsa006200.78535347
47Parkinsons disease_Homo sapiens_hsa050120.78062093
48Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.76120691
49N-Glycan biosynthesis_Homo sapiens_hsa005100.74545480
50Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.73014739
51Amphetamine addiction_Homo sapiens_hsa050310.71776061
52Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.66498021
53Folate biosynthesis_Homo sapiens_hsa007900.66474480
54Protein export_Homo sapiens_hsa030600.65235088
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65163719
56Calcium signaling pathway_Homo sapiens_hsa040200.65032605
57Linoleic acid metabolism_Homo sapiens_hsa005910.64712533
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64331681
59Pertussis_Homo sapiens_hsa051330.62523688
60Rheumatoid arthritis_Homo sapiens_hsa053230.60437804
61Morphine addiction_Homo sapiens_hsa050320.60256208
62Dopaminergic synapse_Homo sapiens_hsa047280.58599737
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.57159434
64alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.56119001
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53708353
66Nitrogen metabolism_Homo sapiens_hsa009100.53382323
67Chemical carcinogenesis_Homo sapiens_hsa052040.50608197
68Measles_Homo sapiens_hsa051620.49972354
69Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.49360998
70Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.48993446
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.48745511
72Renin secretion_Homo sapiens_hsa049240.48507257
73Cocaine addiction_Homo sapiens_hsa050300.47843274
74Alzheimers disease_Homo sapiens_hsa050100.47332396
75Ribosome_Homo sapiens_hsa030100.46730357
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.45205011
77Tuberculosis_Homo sapiens_hsa051520.44856330
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.44792259
79Proteasome_Homo sapiens_hsa030500.44512956
80Metabolic pathways_Homo sapiens_hsa011000.44033228
81Mineral absorption_Homo sapiens_hsa049780.43629711
82Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.42407035
83Asthma_Homo sapiens_hsa053100.42064870
84RNA polymerase_Homo sapiens_hsa030200.41906802
85Hematopoietic cell lineage_Homo sapiens_hsa046400.41795156
86Malaria_Homo sapiens_hsa051440.39227375
87Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.38925060
88NOD-like receptor signaling pathway_Homo sapiens_hsa046210.37345141
89Huntingtons disease_Homo sapiens_hsa050160.37277043
90Jak-STAT signaling pathway_Homo sapiens_hsa046300.37207213
91Toll-like receptor signaling pathway_Homo sapiens_hsa046200.36952959
92Fat digestion and absorption_Homo sapiens_hsa049750.36692421
93T cell receptor signaling pathway_Homo sapiens_hsa046600.36056889
94Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.34943641
95Ether lipid metabolism_Homo sapiens_hsa005650.33156632
96Legionellosis_Homo sapiens_hsa051340.32782880
97Synaptic vesicle cycle_Homo sapiens_hsa047210.32650263
98Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.32039186
99Glutathione metabolism_Homo sapiens_hsa004800.31637088
100Serotonergic synapse_Homo sapiens_hsa047260.30389676

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »