

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | negative regulation of skeletal muscle tissue development (GO:0048642) | 9.66938832 |
| 2 | regulation of skeletal muscle contraction (GO:0014819) | 9.59336050 |
| 3 | response to muscle activity (GO:0014850) | 9.31133135 |
| 4 | actin-mediated cell contraction (GO:0070252) | 8.37249261 |
| 5 | cellular response to dexamethasone stimulus (GO:0071549) | 7.24076687 |
| 6 | response to dexamethasone (GO:0071548) | 6.70040345 |
| 7 | response to activity (GO:0014823) | 6.46021445 |
| 8 | actin filament-based movement (GO:0030048) | 5.87728585 |
| 9 | striated muscle adaptation (GO:0014888) | 5.81375495 |
| 10 | protein K6-linked ubiquitination (GO:0085020) | 5.68294501 |
| 11 | ribosomal small subunit biogenesis (GO:0042274) | 5.44137805 |
| 12 | viral transcription (GO:0019083) | 5.15213159 |
| 13 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.99155662 |
| 14 | translational termination (GO:0006415) | 4.88909199 |
| 15 | maturation of SSU-rRNA (GO:0030490) | 4.78013738 |
| 16 | muscle adaptation (GO:0043500) | 4.77856488 |
| 17 | regulation of muscle hypertrophy (GO:0014743) | 4.69500706 |
| 18 | dosage compensation (GO:0007549) | 4.63395165 |
| 19 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 4.60518446 |
| 20 | protein trimerization (GO:0070206) | 4.53070126 |
| 21 | translational elongation (GO:0006414) | 4.49560609 |
| 22 | negative regulation of organelle assembly (GO:1902116) | 4.42447902 |
| 23 | response to testosterone (GO:0033574) | 4.31193027 |
| 24 | skeletal muscle contraction (GO:0003009) | 4.25392154 |
| 25 | response to electrical stimulus (GO:0051602) | 4.14022565 |
| 26 | negative regulation of striated muscle tissue development (GO:0045843) | 4.07990337 |
| 27 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.05957067 |
| 28 | muscle organ development (GO:0007517) | 4.05687040 |
| 29 | ribosomal small subunit assembly (GO:0000028) | 4.04907777 |
| 30 | positive regulation of histone H3-K4 methylation (GO:0051571) | 4.02700454 |
| 31 | regulation of DNA methylation (GO:0044030) | 4.00027981 |
| 32 | tissue regeneration (GO:0042246) | 3.98333099 |
| 33 | protein targeting to ER (GO:0045047) | 3.98145269 |
| 34 | cotranslational protein targeting to membrane (GO:0006613) | 3.96932031 |
| 35 | muscle structure development (GO:0061061) | 3.96709353 |
| 36 | negative regulation of muscle tissue development (GO:1901862) | 3.94137251 |
| 37 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.83669921 |
| 38 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.80778628 |
| 39 | negative regulation of muscle organ development (GO:0048635) | 3.78411994 |
| 40 | myotube cell development (GO:0014904) | 3.77085319 |
| 41 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.75833027 |
| 42 | negative regulation of histone acetylation (GO:0035067) | 3.72942107 |
| 43 | protein localization to endoplasmic reticulum (GO:0070972) | 3.70509060 |
| 44 | cellular protein complex disassembly (GO:0043624) | 3.69337855 |
| 45 | regulation of centriole replication (GO:0046599) | 3.68896798 |
| 46 | cellular response to glucocorticoid stimulus (GO:0071385) | 3.68880410 |
| 47 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.66690578 |
| 48 | embryonic skeletal joint morphogenesis (GO:0060272) | 3.62824590 |
| 49 | viral life cycle (GO:0019058) | 3.60395915 |
| 50 | translational initiation (GO:0006413) | 3.56579495 |
| 51 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.49298988 |
| 52 | cellular response to corticosteroid stimulus (GO:0071384) | 3.43986586 |
| 53 | negative regulation of peptidyl-lysine acetylation (GO:2000757) | 3.43781896 |
| 54 | regulation of relaxation of muscle (GO:1901077) | 3.39689245 |
| 55 | cullin deneddylation (GO:0010388) | 3.39139128 |
| 56 | cellular response to ketone (GO:1901655) | 3.37159962 |
| 57 | regulation of gene expression by genetic imprinting (GO:0006349) | 3.35319925 |
| 58 | muscle system process (GO:0003012) | 3.24069848 |
| 59 | viral genome replication (GO:0019079) | 3.23162963 |
| 60 | heparin metabolic process (GO:0030202) | 3.17511489 |
| 61 | heparin biosynthetic process (GO:0030210) | 3.17511489 |
| 62 | negative regulation of fatty acid metabolic process (GO:0045922) | 3.17508977 |
| 63 | protein complex disassembly (GO:0043241) | 3.16399557 |
| 64 | response to inactivity (GO:0014854) | 3.12454115 |
| 65 | negative regulation of protein acetylation (GO:1901984) | 3.12377547 |
| 66 | skeletal muscle fiber development (GO:0048741) | 3.11498280 |
| 67 | muscle contraction (GO:0006936) | 3.08795311 |
| 68 | translation (GO:0006412) | 3.08076183 |
| 69 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 3.06636172 |
| 70 | regulation of histone H3-K9 methylation (GO:0051570) | 3.02197497 |
| 71 | chaperone-mediated protein transport (GO:0072321) | 3.00424102 |
| 72 | pattern specification involved in kidney development (GO:0061004) | 2.96368402 |
| 73 | macromolecular complex disassembly (GO:0032984) | 2.95104245 |
| 74 | protein deneddylation (GO:0000338) | 2.93723726 |
| 75 | heart field specification (GO:0003128) | 2.91339354 |
| 76 | secondary heart field specification (GO:0003139) | 2.91339354 |
| 77 | middle ear morphogenesis (GO:0042474) | 2.90878769 |
| 78 | sarcoplasmic reticulum calcium ion transport (GO:0070296) | 2.88589751 |
| 79 | genetic imprinting (GO:0071514) | 2.85705486 |
| 80 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.80136648 |
| 81 | rRNA processing (GO:0006364) | 2.78189479 |
| 82 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.73081374 |
| 83 | ATP synthesis coupled proton transport (GO:0015986) | 2.73081374 |
| 84 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.71766854 |
| 85 | protein neddylation (GO:0045116) | 2.68708992 |
| 86 | muscle cell cellular homeostasis (GO:0046716) | 2.67983940 |
| 87 | protein targeting to membrane (GO:0006612) | 2.65961899 |
| 88 | outer ear morphogenesis (GO:0042473) | 2.63776212 |
| 89 | rRNA metabolic process (GO:0016072) | 2.63124251 |
| 90 | postreplication repair (GO:0006301) | 2.62988039 |
| 91 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 2.62742706 |
| 92 | negative regulation of histone methylation (GO:0031061) | 2.60757156 |
| 93 | response to gravity (GO:0009629) | 15.1563391 |
| 94 | skeletal muscle adaptation (GO:0043501) | 13.5264518 |
| 95 | striated muscle atrophy (GO:0014891) | 13.2603792 |
| 96 | muscle atrophy (GO:0014889) | 12.1302448 |
| 97 | negative regulation of muscle hypertrophy (GO:0014741) | 11.2399072 |
| 98 | skeletal muscle tissue regeneration (GO:0043403) | 10.6573919 |
| 99 | actin-myosin filament sliding (GO:0033275) | 10.2188010 |
| 100 | muscle filament sliding (GO:0030049) | 10.2188010 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 8.55854303 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 7.98651153 |
| 3 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 6.34666493 |
| 4 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 6.01330502 |
| 5 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.41080977 |
| 6 | TAF15_26573619_Chip-Seq_HEK293_Human | 4.04061981 |
| 7 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.94531974 |
| 8 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.15711334 |
| 9 | FUS_26573619_Chip-Seq_HEK293_Human | 3.06081164 |
| 10 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.82047711 |
| 11 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.48621502 |
| 12 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.26506003 |
| 13 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.17950897 |
| 14 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 2.17855533 |
| 15 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.06246194 |
| 16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.04548271 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.97506018 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.96682629 |
| 19 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.86127171 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.84915318 |
| 21 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.73531544 |
| 22 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.73024953 |
| 23 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.66270076 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.61085999 |
| 25 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.55494211 |
| 26 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.55400494 |
| 27 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.54185816 |
| 28 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.48961220 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.42170709 |
| 30 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.39574579 |
| 31 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.36685197 |
| 32 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.36041075 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.33291394 |
| 34 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.31004457 |
| 35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.30226901 |
| 36 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.29081769 |
| 37 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.29081769 |
| 38 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.29081769 |
| 39 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.27078162 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25522674 |
| 41 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.22716779 |
| 42 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.19837870 |
| 43 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.19429512 |
| 44 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.14074965 |
| 45 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.14063222 |
| 46 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.13659143 |
| 47 | MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse | 1.12119219 |
| 48 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.11952490 |
| 49 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.11700714 |
| 50 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.11700714 |
| 51 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11185130 |
| 52 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.10901377 |
| 53 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.09655689 |
| 54 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.08944895 |
| 55 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.07014809 |
| 56 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.06434703 |
| 57 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.05568062 |
| 58 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.00686761 |
| 59 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.98762012 |
| 60 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.97515357 |
| 61 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.97351323 |
| 62 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.95619690 |
| 63 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.94659906 |
| 64 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.93894966 |
| 65 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.91881886 |
| 66 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.90251760 |
| 67 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.90235112 |
| 68 | RXR_22108803_ChIP-Seq_LS180_Human | 0.89256781 |
| 69 | KDM2B_26808549_Chip-Seq_REH_Human | 0.87076272 |
| 70 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.84743856 |
| 71 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.83630848 |
| 72 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.81967669 |
| 73 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.81457421 |
| 74 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.81314280 |
| 75 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.79912459 |
| 76 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.78960582 |
| 77 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.78729097 |
| 78 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.78369480 |
| 79 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.78060175 |
| 80 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.77082971 |
| 81 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.76969357 |
| 82 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.73860035 |
| 83 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.73154746 |
| 84 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.72496522 |
| 85 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.72251084 |
| 86 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.72176206 |
| 87 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.69568611 |
| 88 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.67645451 |
| 89 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.67645163 |
| 90 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.67257665 |
| 91 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.66317951 |
| 92 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.65793555 |
| 93 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.65032375 |
| 94 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.64035333 |
| 95 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.63810761 |
| 96 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.62152208 |
| 97 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.61904561 |
| 98 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.61895323 |
| 99 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.61396742 |
| 100 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.61037653 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000747_muscle_weakness | 5.97122903 |
| 2 | MP0004145_abnormal_muscle_electrophysio | 5.82027516 |
| 3 | MP0003705_abnormal_hypodermis_morpholog | 4.87637039 |
| 4 | MP0002089_abnormal_postnatal_growth/wei | 4.79778286 |
| 5 | MP0000749_muscle_degeneration | 4.26519648 |
| 6 | MP0004036_abnormal_muscle_relaxation | 4.25280297 |
| 7 | MP0002269_muscular_atrophy | 4.17474126 |
| 8 | MP0000759_abnormal_skeletal_muscle | 3.66344078 |
| 9 | MP0005083_abnormal_biliary_tract | 3.21891099 |
| 10 | MP0002108_abnormal_muscle_morphology | 3.05307856 |
| 11 | MP0004087_abnormal_muscle_fiber | 2.91131461 |
| 12 | MP0002106_abnormal_muscle_physiology | 2.84130850 |
| 13 | MP0005620_abnormal_muscle_contractility | 2.66508994 |
| 14 | MP0000566_synostosis | 2.64317861 |
| 15 | MP0000750_abnormal_muscle_regeneration | 2.31083068 |
| 16 | MP0005369_muscle_phenotype | 2.27030164 |
| 17 | MP0000733_abnormal_muscle_development | 2.21369209 |
| 18 | MP0003959_abnormal_lean_body | 2.09131625 |
| 19 | MP0000751_myopathy | 2.06675339 |
| 20 | MP0002638_abnormal_pupillary_reflex | 1.92700476 |
| 21 | MP0003123_paternal_imprinting | 1.91212616 |
| 22 | MP0009250_abnormal_appendicular_skeleto | 1.77100251 |
| 23 | MP0003937_abnormal_limbs/digits/tail_de | 1.73868874 |
| 24 | MP0002896_abnormal_bone_mineralization | 1.64470249 |
| 25 | MP0008057_abnormal_DNA_replication | 1.55510429 |
| 26 | MP0004270_analgesia | 1.55416011 |
| 27 | MP0000049_abnormal_middle_ear | 1.54694674 |
| 28 | MP0003646_muscle_fatigue | 1.52139985 |
| 29 | MP0000372_irregular_coat_pigmentation | 1.51161166 |
| 30 | MP0002277_abnormal_respiratory_mucosa | 1.47040168 |
| 31 | MP0002095_abnormal_skin_pigmentation | 1.44864056 |
| 32 | MP0010307_abnormal_tumor_latency | 1.40014644 |
| 33 | MP0009780_abnormal_chondrocyte_physiolo | 1.34391703 |
| 34 | MP0002736_abnormal_nociception_after | 1.32319007 |
| 35 | MP0010030_abnormal_orbit_morphology | 1.26685205 |
| 36 | MP0003045_fibrosis | 1.23857092 |
| 37 | MP0003786_premature_aging | 1.23083341 |
| 38 | MP0009379_abnormal_foot_pigmentation | 1.13960584 |
| 39 | MP0000427_abnormal_hair_cycle | 1.13228563 |
| 40 | MP0003950_abnormal_plasma_membrane | 1.08849271 |
| 41 | MP0000537_abnormal_urethra_morphology | 1.03738163 |
| 42 | MP0001968_abnormal_touch/_nociception | 1.02074846 |
| 43 | MP0002114_abnormal_axial_skeleton | 0.97953384 |
| 44 | MP0002177_abnormal_outer_ear | 0.97040751 |
| 45 | MP0003938_abnormal_ear_development | 0.96491308 |
| 46 | MP0001879_abnormal_lymphatic_vessel | 0.95712407 |
| 47 | MP0004142_abnormal_muscle_tone | 0.94189247 |
| 48 | MP0003385_abnormal_body_wall | 0.93771291 |
| 49 | MP0000678_abnormal_parathyroid_gland | 0.92300706 |
| 50 | MP0001243_abnormal_dermal_layer | 0.87731096 |
| 51 | MP0004084_abnormal_cardiac_muscle | 0.86355894 |
| 52 | MP0002109_abnormal_limb_morphology | 0.84263305 |
| 53 | MP0002115_abnormal_skeleton_extremities | 0.82685233 |
| 54 | MP0002138_abnormal_hepatobiliary_system | 0.82105880 |
| 55 | MP0000631_abnormal_neuroendocrine_gland | 0.81302455 |
| 56 | MP0004130_abnormal_muscle_cell | 0.81070697 |
| 57 | MP0003755_abnormal_palate_morphology | 0.79220800 |
| 58 | MP0004484_altered_response_of | 0.77777258 |
| 59 | MP0000467_abnormal_esophagus_morphology | 0.75446244 |
| 60 | MP0002127_abnormal_cardiovascular_syste | 0.74791167 |
| 61 | MP0004215_abnormal_myocardial_fiber | 0.74063837 |
| 62 | MP0008438_abnormal_cutaneous_collagen | 0.73806833 |
| 63 | MP0003880_abnormal_central_pattern | 0.71737431 |
| 64 | MP0002876_abnormal_thyroid_physiology | 0.71304424 |
| 65 | MP0003315_abnormal_perineum_morphology | 0.68400439 |
| 66 | MP0002160_abnormal_reproductive_system | 0.65537054 |
| 67 | MP0005423_abnormal_somatic_nervous | 0.64428364 |
| 68 | MP0003936_abnormal_reproductive_system | 0.61827740 |
| 69 | MP0002837_dystrophic_cardiac_calcinosis | 0.60705159 |
| 70 | MP0004134_abnormal_chest_morphology | 0.59309974 |
| 71 | MP0002116_abnormal_craniofacial_bone | 0.58999487 |
| 72 | MP0003942_abnormal_urinary_system | 0.58329056 |
| 73 | MP0005452_abnormal_adipose_tissue | 0.57153110 |
| 74 | MP0000627_abnormal_mammary_gland | 0.56334807 |
| 75 | MP0003806_abnormal_nucleotide_metabolis | 0.54149006 |
| 76 | MP0001340_abnormal_eyelid_morphology | 0.53046167 |
| 77 | MP0004885_abnormal_endolymph | 0.49848912 |
| 78 | MP0000163_abnormal_cartilage_morphology | 0.49280471 |
| 79 | MP0000534_abnormal_ureter_morphology | 0.49217987 |
| 80 | MP0003567_abnormal_fetal_cardiomyocyte | 0.49104779 |
| 81 | MP0000428_abnormal_craniofacial_morphol | 0.48453484 |
| 82 | MP0001905_abnormal_dopamine_level | 0.48267250 |
| 83 | MP0001299_abnormal_eye_distance/ | 0.47841308 |
| 84 | MP0001661_extended_life_span | 0.47311854 |
| 85 | MP0003119_abnormal_digestive_system | 0.47139875 |
| 86 | MP0000778_abnormal_nervous_system | 0.46549893 |
| 87 | MP0000377_abnormal_hair_follicle | 0.46359832 |
| 88 | MP0001943_abnormal_respiration | 0.45913330 |
| 89 | MP0000266_abnormal_heart_morphology | 0.45750001 |
| 90 | MP0004043_abnormal_pH_regulation | 0.45285441 |
| 91 | MP0005645_abnormal_hypothalamus_physiol | 0.45142134 |
| 92 | MP0002184_abnormal_innervation | 0.44568438 |
| 93 | MP0002932_abnormal_joint_morphology | 0.41779148 |
| 94 | MP0002332_abnormal_exercise_endurance | 0.41587009 |
| 95 | MP0005334_abnormal_fat_pad | 0.41489347 |
| 96 | MP0001485_abnormal_pinna_reflex | 0.41395243 |
| 97 | MP0000470_abnormal_stomach_morphology | 0.40459171 |
| 98 | MP0005275_abnormal_skin_tensile | 0.39980309 |
| 99 | MP0008770_decreased_survivor_rate | 0.39642298 |
| 100 | MP0001502_abnormal_circadian_rhythm | 0.39615856 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Palpebral edema (HP:0100540) | 9.31743004 |
| 2 | Distal arthrogryposis (HP:0005684) | 7.53000140 |
| 3 | Nemaline bodies (HP:0003798) | 7.09858295 |
| 4 | Exercise-induced myalgia (HP:0003738) | 7.05294686 |
| 5 | Mask-like facies (HP:0000298) | 6.98450935 |
| 6 | Round ear (HP:0100830) | 6.86779498 |
| 7 | Absent phalangeal crease (HP:0006109) | 6.51312208 |
| 8 | Ulnar deviation of the wrist (HP:0003049) | 6.38066943 |
| 9 | Calcaneovalgus deformity (HP:0001848) | 5.99686691 |
| 10 | Deformed tarsal bones (HP:0008119) | 5.89121560 |
| 11 | Muscle fiber inclusion bodies (HP:0100299) | 5.72651287 |
| 12 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 5.63052025 |
| 13 | Abnormal finger flexion creases (HP:0006143) | 5.54599654 |
| 14 | Hyperkalemia (HP:0002153) | 5.33840939 |
| 15 | Type 1 muscle fiber predominance (HP:0003803) | 4.84388465 |
| 16 | Periorbital edema (HP:0100539) | 4.48005955 |
| 17 | Facial edema (HP:0000282) | 4.32903174 |
| 18 | Myopathic facies (HP:0002058) | 4.04293429 |
| 19 | Exercise-induced muscle cramps (HP:0003710) | 3.76787735 |
| 20 | Myotonia (HP:0002486) | 3.67624999 |
| 21 | Down-sloping shoulders (HP:0200021) | 3.59205851 |
| 22 | Myoglobinuria (HP:0002913) | 3.55056387 |
| 23 | Increased connective tissue (HP:0009025) | 3.41134406 |
| 24 | Abnormality of the calcaneus (HP:0008364) | 3.09858993 |
| 25 | Abnormality of potassium homeostasis (HP:0011042) | 2.99822501 |
| 26 | Fibular aplasia (HP:0002990) | 2.99023602 |
| 27 | Microglossia (HP:0000171) | 2.85956151 |
| 28 | Abnormality of the parietal bone (HP:0002696) | 2.84086399 |
| 29 | Rectal prolapse (HP:0002035) | 2.76368773 |
| 30 | Difficulty running (HP:0009046) | 2.74430967 |
| 31 | Metatarsus adductus (HP:0001840) | 2.69541192 |
| 32 | Hyperphosphatemia (HP:0002905) | 2.62105524 |
| 33 | Rhabdomyolysis (HP:0003201) | 2.60565763 |
| 34 | Supernumerary bones of the axial skeleton (HP:0009144) | 2.59474250 |
| 35 | Neoplasm of the heart (HP:0100544) | 2.59281446 |
| 36 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.58994849 |
| 37 | 3-Methylglutaconic aciduria (HP:0003535) | 2.56361201 |
| 38 | Stenosis of the external auditory canal (HP:0000402) | 2.52771066 |
| 39 | Decreased circulating renin level (HP:0003351) | 2.52424652 |
| 40 | Muscle stiffness (HP:0003552) | 2.50822697 |
| 41 | Lip pit (HP:0100267) | 2.50109155 |
| 42 | Nonprogressive disorder (HP:0003680) | 2.49424021 |
| 43 | Mesomelia (HP:0003027) | 2.43629179 |
| 44 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.43322849 |
| 45 | Supernumerary ribs (HP:0005815) | 2.42160472 |
| 46 | Hyperuricemia (HP:0002149) | 2.36891545 |
| 47 | Increased purine levels (HP:0004368) | 2.36891545 |
| 48 | Bell-shaped thorax (HP:0001591) | 2.36507574 |
| 49 | Acute necrotizing encephalopathy (HP:0006965) | 2.31396894 |
| 50 | Reticulocytopenia (HP:0001896) | 2.12388335 |
| 51 | Oligomenorrhea (HP:0000876) | 2.09531578 |
| 52 | Gout (HP:0001997) | 1.99582157 |
| 53 | Progressive macrocephaly (HP:0004481) | 1.99416891 |
| 54 | Abnormality of the peritoneum (HP:0002585) | 1.98521014 |
| 55 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.98289558 |
| 56 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.98073476 |
| 57 | Abnormality of the 4th metacarpal (HP:0010012) | 1.97882116 |
| 58 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.88984208 |
| 59 | Hypoplasia of the radius (HP:0002984) | 1.88829862 |
| 60 | Tarsal synostosis (HP:0008368) | 1.88088031 |
| 61 | Malignant hyperthermia (HP:0002047) | 1.82393035 |
| 62 | Synostosis involving bones of the lower limbs (HP:0009138) | 1.81274898 |
| 63 | Synostosis involving bones of the feet (HP:0009140) | 1.81274898 |
| 64 | Hypoplastic ischia (HP:0003175) | 1.81079958 |
| 65 | Hypokalemia (HP:0002900) | 1.79370708 |
| 66 | Paralysis (HP:0003470) | 1.77125874 |
| 67 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.76974448 |
| 68 | Short 4th metacarpal (HP:0010044) | 1.76974448 |
| 69 | Ulnar deviation of finger (HP:0009465) | 1.75571295 |
| 70 | Short phalanx of the thumb (HP:0009660) | 1.74490574 |
| 71 | Maternal diabetes (HP:0009800) | 1.72837657 |
| 72 | Abnormality of chloride homeostasis (HP:0011422) | 1.72787591 |
| 73 | Abnormality of the 2nd finger (HP:0004100) | 1.70498304 |
| 74 | 2-3 toe syndactyly (HP:0004691) | 1.69761239 |
| 75 | Increased variability in muscle fiber diameter (HP:0003557) | 1.68448021 |
| 76 | Toxemia of pregnancy (HP:0100603) | 1.67286278 |
| 77 | Hypoplastic iliac wings (HP:0002866) | 1.65442648 |
| 78 | Abnormality of the columella (HP:0009929) | 1.63568983 |
| 79 | Acute encephalopathy (HP:0006846) | 1.63073051 |
| 80 | Delayed CNS myelination (HP:0002188) | 1.63066852 |
| 81 | Macrocytic anemia (HP:0001972) | 1.61330285 |
| 82 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.61247610 |
| 83 | Skin pits (HP:0100276) | 1.59590394 |
| 84 | Abnormality of the ischium (HP:0003174) | 1.57531867 |
| 85 | Congenital hip dislocation (HP:0001374) | 1.55918633 |
| 86 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.55797407 |
| 87 | Metabolic acidosis (HP:0001942) | 1.52706423 |
| 88 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.50582269 |
| 89 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.49013621 |
| 90 | Abnormality of alanine metabolism (HP:0010916) | 1.49013621 |
| 91 | Hyperalaninemia (HP:0003348) | 1.49013621 |
| 92 | Abnormality of purine metabolism (HP:0004352) | 1.47006853 |
| 93 | Mitochondrial inheritance (HP:0001427) | 1.46573011 |
| 94 | Hypoalphalipoproteinemia (HP:0003233) | 1.45372483 |
| 95 | Intellectual disability, moderate (HP:0002342) | 1.44773029 |
| 96 | Macroorchidism (HP:0000053) | 1.42157124 |
| 97 | Aplasia/Hypoplasia of the phalanges of the thumb (HP:0009658) | 1.41500054 |
| 98 | Abnormal drinking behavior (HP:0030082) | 1.40741432 |
| 99 | Polydipsia (HP:0001959) | 1.40741432 |
| 100 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.39466715 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PHKG2 | 5.28316250 |
| 2 | PHKG1 | 5.28316250 |
| 3 | TIE1 | 4.70014310 |
| 4 | OBSCN | 4.59006098 |
| 5 | NME2 | 3.79429852 |
| 6 | WNK4 | 3.72520328 |
| 7 | WNK1 | 3.08398255 |
| 8 | CAMK1D | 2.91361774 |
| 9 | TYRO3 | 2.30268361 |
| 10 | PIK3CA | 2.21865554 |
| 11 | CAMK1G | 2.17669045 |
| 12 | CAMKK2 | 2.03869242 |
| 13 | TXK | 1.93633650 |
| 14 | IRAK1 | 1.90815689 |
| 15 | SCYL2 | 1.77282154 |
| 16 | PDK2 | 1.68735470 |
| 17 | ARAF | 1.63149523 |
| 18 | LIMK1 | 1.57522393 |
| 19 | CCNB1 | 1.52809717 |
| 20 | CDK4 | 1.48392766 |
| 21 | TLK1 | 1.48004355 |
| 22 | JAK3 | 1.45363857 |
| 23 | CHEK2 | 1.42917381 |
| 24 | PIK3CG | 1.38405565 |
| 25 | DMPK | 1.37767266 |
| 26 | MAPK13 | 1.36188160 |
| 27 | STK16 | 1.35971348 |
| 28 | CAMK2G | 1.32005993 |
| 29 | AURKA | 1.29100953 |
| 30 | MST4 | 1.24950379 |
| 31 | MAP3K12 | 1.20005304 |
| 32 | STK39 | 1.17889979 |
| 33 | CASK | 1.17750549 |
| 34 | SRPK1 | 1.16701118 |
| 35 | EPHB2 | 1.15742215 |
| 36 | ILK | 1.00032893 |
| 37 | DYRK1B | 0.98298860 |
| 38 | NUAK1 | 0.95376251 |
| 39 | BUB1 | 0.94820242 |
| 40 | MAPK7 | 0.92612726 |
| 41 | VRK2 | 0.84358165 |
| 42 | CAMK1 | 0.76379677 |
| 43 | MARK3 | 0.76284095 |
| 44 | MUSK | 0.74863244 |
| 45 | TESK1 | 0.68151155 |
| 46 | TAF1 | 0.66978323 |
| 47 | MOS | 0.66761639 |
| 48 | BCKDK | 0.66578769 |
| 49 | DYRK3 | 0.64540455 |
| 50 | CSNK1G1 | 0.64071425 |
| 51 | LRRK2 | 0.61197685 |
| 52 | PRKG1 | 0.60900630 |
| 53 | CSNK1A1L | 0.58111488 |
| 54 | CAMK4 | 0.57943195 |
| 55 | CAMKK1 | 0.57671681 |
| 56 | PRKD3 | 0.56906528 |
| 57 | SGK2 | 0.54323297 |
| 58 | TESK2 | 0.52851645 |
| 59 | CSNK1G2 | 0.51776646 |
| 60 | SGK1 | 0.50782527 |
| 61 | TEC | 0.50747965 |
| 62 | PIM1 | 0.45329259 |
| 63 | MAPK12 | 0.44294043 |
| 64 | CSNK1G3 | 0.44260290 |
| 65 | RPS6KA5 | 0.42171806 |
| 66 | PIM2 | 0.41679929 |
| 67 | SGK223 | 0.41149794 |
| 68 | SGK494 | 0.41149794 |
| 69 | DYRK2 | 0.41004044 |
| 70 | DDR2 | 0.40781537 |
| 71 | ABL2 | 0.39507955 |
| 72 | EIF2AK2 | 0.38981429 |
| 73 | RPS6KA4 | 0.35492632 |
| 74 | NEK1 | 0.34508510 |
| 75 | RPS6KL1 | 0.32725403 |
| 76 | RPS6KC1 | 0.32725403 |
| 77 | RPS6KA6 | 0.32398384 |
| 78 | BRAF | 0.31599298 |
| 79 | OXSR1 | 0.31177937 |
| 80 | MAP2K3 | 0.28982134 |
| 81 | CSNK2A1 | 0.28602050 |
| 82 | VRK1 | 0.28279097 |
| 83 | ADRBK2 | 0.27074868 |
| 84 | SGK3 | 0.26984618 |
| 85 | DAPK1 | 0.26683126 |
| 86 | PINK1 | 0.26231508 |
| 87 | PRKACA | 0.25120989 |
| 88 | PRKACB | 0.23545923 |
| 89 | PLK4 | 0.23483361 |
| 90 | MAP2K7 | 0.23306745 |
| 91 | ATR | 0.22865637 |
| 92 | MKNK2 | 0.22171815 |
| 93 | AKT2 | 0.19445714 |
| 94 | FGFR1 | 0.17883078 |
| 95 | RPS6KA3 | 0.17592121 |
| 96 | CSNK2A2 | 0.16631946 |
| 97 | NEK2 | 0.16093703 |
| 98 | PAK1 | 0.14368044 |
| 99 | TNIK | 0.11305591 |
| 100 | MAP3K11 | 0.10375409 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.44193156 |
| 2 | Tight junction_Homo sapiens_hsa04530 | 4.29975270 |
| 3 | Regulation of autophagy_Homo sapiens_hsa04140 | 3.53314500 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.55282554 |
| 5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.35359101 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.12870195 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.10942123 |
| 8 | Proteasome_Homo sapiens_hsa03050 | 1.96453030 |
| 9 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.85761917 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 1.82868130 |
| 11 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.78262642 |
| 12 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 1.73251678 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.60784736 |
| 14 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.58229124 |
| 15 | Spliceosome_Homo sapiens_hsa03040 | 1.57452304 |
| 16 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.54554795 |
| 17 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.52561215 |
| 18 | Wnt signaling pathway_Homo sapiens_hsa04310 | 1.49965384 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.49178215 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.46944687 |
| 21 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.42556921 |
| 22 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.37656141 |
| 23 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.29459872 |
| 24 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.26702813 |
| 25 | RNA polymerase_Homo sapiens_hsa03020 | 1.24884097 |
| 26 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.20861698 |
| 27 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.20607207 |
| 28 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.17215472 |
| 29 | Circadian entrainment_Homo sapiens_hsa04713 | 1.14957958 |
| 30 | Insulin secretion_Homo sapiens_hsa04911 | 1.09958794 |
| 31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.09843661 |
| 32 | Renin secretion_Homo sapiens_hsa04924 | 1.07852766 |
| 33 | Circadian rhythm_Homo sapiens_hsa04710 | 1.06946402 |
| 34 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.06368648 |
| 35 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.06268196 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.06200305 |
| 37 | Sulfur relay system_Homo sapiens_hsa04122 | 1.05303380 |
| 38 | Protein export_Homo sapiens_hsa03060 | 1.02274806 |
| 39 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.00918628 |
| 40 | Long-term potentiation_Homo sapiens_hsa04720 | 0.98090923 |
| 41 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.91279930 |
| 42 | Morphine addiction_Homo sapiens_hsa05032 | 0.90276395 |
| 43 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.89574634 |
| 44 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.86521454 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.84944424 |
| 46 | Adherens junction_Homo sapiens_hsa04520 | 0.83709332 |
| 47 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.81884867 |
| 48 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.81424712 |
| 49 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.80802670 |
| 50 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.78796251 |
| 51 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.77183663 |
| 52 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.76634270 |
| 53 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.75476526 |
| 54 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.69405057 |
| 55 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.68099148 |
| 56 | Salivary secretion_Homo sapiens_hsa04970 | 0.67862466 |
| 57 | RNA transport_Homo sapiens_hsa03013 | 0.66441695 |
| 58 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.65449815 |
| 59 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.64929782 |
| 60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61782801 |
| 61 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.61290993 |
| 62 | Purine metabolism_Homo sapiens_hsa00230 | 0.60554382 |
| 63 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.57987201 |
| 64 | Axon guidance_Homo sapiens_hsa04360 | 0.54154146 |
| 65 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.53805672 |
| 66 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.52320634 |
| 67 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.51613711 |
| 68 | Long-term depression_Homo sapiens_hsa04730 | 0.51117278 |
| 69 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.50648481 |
| 70 | Olfactory transduction_Homo sapiens_hsa04740 | 0.50353116 |
| 71 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.49689416 |
| 72 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.49008066 |
| 73 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.45128018 |
| 74 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.44828364 |
| 75 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.44720744 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.42359830 |
| 77 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.42232973 |
| 78 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41828171 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41618257 |
| 80 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.41332312 |
| 81 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.40467188 |
| 82 | DNA replication_Homo sapiens_hsa03030 | 0.36887852 |
| 83 | GABAergic synapse_Homo sapiens_hsa04727 | 0.36011252 |
| 84 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.35311316 |
| 85 | Melanoma_Homo sapiens_hsa05218 | 0.31482612 |
| 86 | Nicotine addiction_Homo sapiens_hsa05033 | 0.31224378 |
| 87 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.30176673 |
| 88 | Melanogenesis_Homo sapiens_hsa04916 | 0.30136116 |
| 89 | Alcoholism_Homo sapiens_hsa05034 | 0.29491600 |
| 90 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.28755734 |
| 91 | Measles_Homo sapiens_hsa05162 | 0.27871469 |
| 92 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.27631562 |
| 93 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.27324958 |
| 94 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.27235706 |
| 95 | Homologous recombination_Homo sapiens_hsa03440 | 0.26866965 |
| 96 | Asthma_Homo sapiens_hsa05310 | 0.26814956 |
| 97 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.25461598 |
| 98 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.24109032 |
| 99 | Mineral absorption_Homo sapiens_hsa04978 | 0.23849599 |
| 100 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.22188581 |

