RPS23P9

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.03337944
2translational termination (GO:0006415)6.74118361
3ribosomal small subunit biogenesis (GO:0042274)6.27190063
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.03986532
5protein targeting to ER (GO:0045047)5.95433921
6cotranslational protein targeting to membrane (GO:0006613)5.94866788
7ribosomal small subunit assembly (GO:0000028)5.84825323
8maturation of SSU-rRNA (GO:0030490)5.73303820
9translational elongation (GO:0006414)5.67313988
10ATP synthesis coupled proton transport (GO:0015986)5.64574907
11energy coupled proton transport, down electrochemical gradient (GO:0015985)5.64574907
12establishment of protein localization to endoplasmic reticulum (GO:0072599)5.64282513
13protein localization to endoplasmic reticulum (GO:0070972)5.62636100
14ribosomal large subunit biogenesis (GO:0042273)5.41114374
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.40149941
16signal peptide processing (GO:0006465)5.28316863
17epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.08042078
18cellular protein complex disassembly (GO:0043624)5.02500635
19viral life cycle (GO:0019058)4.99254625
20nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.86313551
21translational initiation (GO:0006413)4.56255030
22mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.45559015
23L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.40509941
24RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.30451762
25tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.30451762
26protein complex disassembly (GO:0043241)4.21116809
27regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.18706638
28DNA deamination (GO:0045006)4.11703945
29macromolecular complex disassembly (GO:0032984)3.98155013
30protein targeting to membrane (GO:0006612)3.95408548
31respiratory electron transport chain (GO:0022904)3.92812631
32regulation of isotype switching to IgG isotypes (GO:0048302)3.90103977
33electron transport chain (GO:0022900)3.87113946
34prenylation (GO:0097354)3.86496374
35protein prenylation (GO:0018342)3.86496374
36translation (GO:0006412)3.79602612
37valine metabolic process (GO:0006573)3.79369662
38L-methionine salvage (GO:0071267)3.76739230
39L-methionine biosynthetic process (GO:0071265)3.76739230
40amino acid salvage (GO:0043102)3.76739230
41nuclear-transcribed mRNA catabolic process (GO:0000956)3.67800294
42exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.63138640
43GTP biosynthetic process (GO:0006183)3.60385660
44establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.56727136
45mitochondrion transport along microtubule (GO:0047497)3.56727136
46positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.51428089
47mRNA catabolic process (GO:0006402)3.46456053
48nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.44741849
49purine nucleoside triphosphate biosynthetic process (GO:0009145)3.42767126
50protein complex biogenesis (GO:0070271)3.39576788
51purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.37826039
52regulation of regulatory T cell differentiation (GO:0045589)3.37120026
53ATP biosynthetic process (GO:0006754)3.30701948
54behavioral response to nicotine (GO:0035095)3.30578414
55detection of light stimulus involved in sensory perception (GO:0050962)3.22902632
56detection of light stimulus involved in visual perception (GO:0050908)3.22902632
57RNA catabolic process (GO:0006401)3.19123233
58protein neddylation (GO:0045116)3.18271594
59ribonucleoprotein complex biogenesis (GO:0022613)3.14145955
60nucleotide transmembrane transport (GO:1901679)3.13299713
61establishment of mitochondrion localization (GO:0051654)3.12844112
62cardiovascular system development (GO:0072358)3.12294384
63cellular component biogenesis (GO:0044085)3.11478121
64UTP biosynthetic process (GO:0006228)3.04370864
65axoneme assembly (GO:0035082)3.02898037
66tryptophan metabolic process (GO:0006568)3.01612956
67mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.00786414
68mitochondrial respiratory chain complex I assembly (GO:0032981)3.00786414
69NADH dehydrogenase complex assembly (GO:0010257)3.00786414
70indolalkylamine metabolic process (GO:0006586)2.99061169
71positive regulation of defense response to virus by host (GO:0002230)2.95729723
72ribonucleoside triphosphate biosynthetic process (GO:0009201)2.93954100
73termination of RNA polymerase III transcription (GO:0006386)2.91934621
74transcription elongation from RNA polymerase III promoter (GO:0006385)2.91934621
75mitochondrial respiratory chain complex assembly (GO:0033108)2.91071504
76establishment of protein localization to mitochondrial membrane (GO:0090151)2.89366484
77regulation of podosome assembly (GO:0071801)2.89160380
78spindle assembly involved in mitosis (GO:0090307)2.88121567
79viral protein processing (GO:0019082)2.87565130
80chaperone-mediated protein transport (GO:0072321)2.87272395
81cytidine metabolic process (GO:0046087)2.84941255
82cytidine catabolic process (GO:0006216)2.84941255
83cytidine deamination (GO:0009972)2.84941255
84L-fucose catabolic process (GO:0042355)2.83670386
85fucose catabolic process (GO:0019317)2.83670386
86L-fucose metabolic process (GO:0042354)2.83670386
87UTP metabolic process (GO:0046051)2.83204045
88kynurenine metabolic process (GO:0070189)2.79989474
89negative regulation of appetite (GO:0032099)2.77941544
90negative regulation of response to food (GO:0032096)2.77941544
91positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.76763352
92regulation of respiratory burst (GO:0060263)2.76305910
93regulation of chronic inflammatory response (GO:0002676)2.72321645
94seminiferous tubule development (GO:0072520)2.70343412
95positive regulation of protein homodimerization activity (GO:0090073)2.67211716
96DNA synthesis involved in DNA repair (GO:0000731)2.67090929
97hydrogen ion transmembrane transport (GO:1902600)2.64884110
98regulation of cilium movement (GO:0003352)2.64551740
99nucleoside triphosphate biosynthetic process (GO:0009142)2.64536804
100rRNA catabolic process (GO:0016075)2.62288163

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.54473460
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.28748693
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.04385063
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.27783916
5ELF1_17652178_ChIP-ChIP_JURKAT_Human2.99274225
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.79961052
7CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.54375217
8EZH2_22144423_ChIP-Seq_EOC_Human2.51981897
9BP1_19119308_ChIP-ChIP_Hs578T_Human2.44092547
10ZNF274_21170338_ChIP-Seq_K562_Hela2.42793804
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.42731478
12VDR_22108803_ChIP-Seq_LS180_Human2.35361020
13ETS1_20019798_ChIP-Seq_JURKAT_Human2.35014144
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.33442154
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.32807610
16IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.31835709
17IRF1_19129219_ChIP-ChIP_H3396_Human2.29661394
18MYC_18555785_ChIP-Seq_MESCs_Mouse2.25089972
19TDRD3_21172665_ChIP-Seq_MCF-7_Human2.17586471
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.12281404
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.11296241
22VDR_23849224_ChIP-Seq_CD4+_Human2.04739231
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.95531036
24FOXP3_21729870_ChIP-Seq_TREG_Human1.79095486
25STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.77655823
26PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.67870693
27CREB1_15753290_ChIP-ChIP_HEK293T_Human1.63280738
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62156434
29MYC_18358816_ChIP-ChIP_MESCs_Mouse1.59631372
30PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.55230308
31GATA3_21878914_ChIP-Seq_MCF-7_Human1.49524088
32FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48664156
33TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.47733382
34TP53_22573176_ChIP-Seq_HFKS_Human1.47335922
35NOTCH1_21737748_ChIP-Seq_TLL_Human1.47311981
36RUNX_20019798_ChIP-Seq_JUKART_Human1.47141534
37CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.41619325
38IRF8_22096565_ChIP-ChIP_GC-B_Human1.40956375
39POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.40868405
40BCL6_27268052_Chip-Seq_Bcells_Human1.39129518
41ERA_21632823_ChIP-Seq_H3396_Human1.36191694
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.36094253
43FOXA1_25329375_ChIP-Seq_VCAP_Human1.34808450
44FOXA1_27270436_Chip-Seq_PROSTATE_Human1.34808450
45TTF2_22483619_ChIP-Seq_HELA_Human1.33879249
46CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.33141505
47EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.32286053
48CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.31383350
49FOXH1_21741376_ChIP-Seq_EPCs_Human1.28690830
50MYC_18940864_ChIP-ChIP_HL60_Human1.26774217
51RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.26656564
52EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.25068909
53PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.24941537
54LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.24095170
55TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.22445191
56MYC_19079543_ChIP-ChIP_MESCs_Mouse1.22348701
57FOXH1_21741376_ChIP-Seq_ESCs_Human1.19406015
58MYB_26560356_Chip-Seq_TH2_Human1.18737527
59EWS_26573619_Chip-Seq_HEK293_Human1.18653943
60NANOG_20526341_ChIP-Seq_ESCs_Human1.17624591
61TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.17533737
62GATA3_26560356_Chip-Seq_TH2_Human1.16695194
63SRF_21415370_ChIP-Seq_HL-1_Mouse1.15566929
64STAT1_20625510_ChIP-Seq_HELA_Human1.15503112
65NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.15088740
66SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.11274663
67P300_27268052_Chip-Seq_Bcells_Human1.11256422
68IGF1R_20145208_ChIP-Seq_DFB_Human1.08719805
69NFE2_27457419_Chip-Seq_LIVER_Mouse1.08494134
70PCGF2_27294783_Chip-Seq_NPCs_Mouse1.08335376
71ELK1_19687146_ChIP-ChIP_HELA_Human1.08059313
72E2F1_20622854_ChIP-Seq_HELA_Human1.04703011
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.04322311
74SUZ12_27294783_Chip-Seq_NPCs_Mouse1.04062787
75TAF2_19829295_ChIP-Seq_ESCs_Human1.02509403
76GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.00607383
77BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.00181004
78CTBP1_25329375_ChIP-Seq_LNCAP_Human0.99237593
79GATA3_27048872_Chip-Seq_THYMUS_Human0.99229276
80GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98761828
81AR_20517297_ChIP-Seq_VCAP_Human0.98510333
82XRN2_22483619_ChIP-Seq_HELA_Human0.97857812
83EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.96585532
84KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96579349
85AUTS2_25519132_ChIP-Seq_293T-REX_Human0.95712133
86NCOR_22424771_ChIP-Seq_293T_Human0.95019657
87FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.93807676
88MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.93743762
89SOX2_21211035_ChIP-Seq_LN229_Human0.92504085
90CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.92320135
91RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.91663683
92CBX2_27304074_Chip-Seq_ESCs_Mouse0.91182782
93ER_23166858_ChIP-Seq_MCF-7_Human0.91141592
94STAT4_19710469_ChIP-ChIP_TH1__Mouse0.91061877
95GABP_19822575_ChIP-Seq_HepG2_Human0.90011527
96NANOG_19829295_ChIP-Seq_ESCs_Human0.89866839
97SOX2_19829295_ChIP-Seq_ESCs_Human0.89866839
98SA1_27219007_Chip-Seq_Bcells_Human0.89493017
99CTCF_20526341_ChIP-Seq_ESCs_Human0.89383573
100FOXA1_21572438_ChIP-Seq_LNCaP_Human0.88864804

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation8.75186782
2MP0005671_abnormal_response_to3.70829981
3MP0003646_muscle_fatigue3.24081335
4MP0001873_stomach_inflammation2.74204059
5MP0001348_abnormal_lacrimal_gland2.59704638
6MP0003806_abnormal_nucleotide_metabolis2.29268432
7MP0008872_abnormal_physiological_respon2.27374039
8MP0008058_abnormal_DNA_repair2.19513694
9MP0008877_abnormal_DNA_methylation2.00958301
10MP0004145_abnormal_muscle_electrophysio1.95692242
11MP0002163_abnormal_gland_morphology1.94870566
12MP0008789_abnormal_olfactory_epithelium1.91316631
13MP0006292_abnormal_olfactory_placode1.87633442
14MP0008875_abnormal_xenobiotic_pharmacok1.84300408
15MP0004142_abnormal_muscle_tone1.83985980
16MP0005646_abnormal_pituitary_gland1.80052612
17MP0001835_abnormal_antigen_presentation1.79071102
18MP0005377_hearing/vestibular/ear_phenot1.70782453
19MP0003878_abnormal_ear_physiology1.70782453
20MP0003315_abnormal_perineum_morphology1.65095439
21MP0001529_abnormal_vocalization1.62347043
22MP0005645_abnormal_hypothalamus_physiol1.62030003
23MP0001800_abnormal_humoral_immune1.58532350
24MP0005551_abnormal_eye_electrophysiolog1.55154945
25MP0001984_abnormal_olfaction1.54301663
26MP0001968_abnormal_touch/_nociception1.53257057
27MP0001663_abnormal_digestive_system1.48417884
28MP0000685_abnormal_immune_system1.42880917
29MP0005000_abnormal_immune_tolerance1.40621554
30MP0005499_abnormal_olfactory_system1.40492985
31MP0005394_taste/olfaction_phenotype1.40492985
32MP0005387_immune_system_phenotype1.39110608
33MP0001790_abnormal_immune_system1.39110608
34MP0001919_abnormal_reproductive_system1.35955121
35MP0005085_abnormal_gallbladder_physiolo1.35260154
36MP0005389_reproductive_system_phenotype1.27628630
37MP0006072_abnormal_retinal_apoptosis1.23711528
38MP0009333_abnormal_splenocyte_physiolog1.22599072
39MP0002723_abnormal_immune_serum1.21162257
40MP0001986_abnormal_taste_sensitivity1.20236632
41MP0002148_abnormal_hypersensitivity_rea1.19868410
42MP0000372_irregular_coat_pigmentation1.18358030
43MP0009764_decreased_sensitivity_to1.18092263
44MP0002420_abnormal_adaptive_immunity1.16180911
45MP0002272_abnormal_nervous_system1.14423425
46MP0004885_abnormal_endolymph1.13304106
47MP0005379_endocrine/exocrine_gland_phen1.10819585
48MP0002452_abnormal_antigen_presenting1.10322486
49MP0002736_abnormal_nociception_after1.09866537
50MP0001819_abnormal_immune_cell1.09802302
51MP0006082_CNS_inflammation1.09663432
52MP0001905_abnormal_dopamine_level1.05794464
53MP0001440_abnormal_grooming_behavior1.03521078
54MP0005310_abnormal_salivary_gland1.01674152
55MP0003186_abnormal_redox_activity1.00027132
56MP0004858_abnormal_nervous_system0.96999115
57MP0002638_abnormal_pupillary_reflex0.96764946
58MP0009046_muscle_twitch0.94051608
59MP0003436_decreased_susceptibility_to0.93033105
60MP0005025_abnormal_response_to0.92943738
61MP0001970_abnormal_pain_threshold0.91473875
62MP0002557_abnormal_social/conspecific_i0.91308524
63MP0009745_abnormal_behavioral_response0.90882749
64MP0006276_abnormal_autonomic_nervous0.90567482
65MP0005381_digestive/alimentary_phenotyp0.87803671
66MP0000716_abnormal_immune_system0.86758175
67MP0006036_abnormal_mitochondrial_physio0.84616095
68MP0001545_abnormal_hematopoietic_system0.83808101
69MP0005397_hematopoietic_system_phenotyp0.83808101
70MP0002933_joint_inflammation0.82339925
71MP0002405_respiratory_system_inflammati0.82325799
72MP0002006_tumorigenesis0.81757197
73MP0001845_abnormal_inflammatory_respons0.81566701
74MP0005195_abnormal_posterior_eye0.81217284
75MP0002160_abnormal_reproductive_system0.80754524
76MP0003879_abnormal_hair_cell0.80107731
77MP0002837_dystrophic_cardiac_calcinosis0.79309568
78MP0003787_abnormal_imprinting0.79100103
79MP0003866_abnormal_defecation0.78824318
80MP0003763_abnormal_thymus_physiology0.78035428
81MP0002398_abnormal_bone_marrow0.76659889
82MP0003936_abnormal_reproductive_system0.76440587
83MP0002210_abnormal_sex_determination0.75853038
84MP0009785_altered_susceptibility_to0.73646713
85MP0001485_abnormal_pinna_reflex0.73140238
86MP0003252_abnormal_bile_duct0.72259370
87MP0002234_abnormal_pharynx_morphology0.72233570
88MP0004043_abnormal_pH_regulation0.71702412
89MP0002733_abnormal_thermal_nociception0.71176770
90MP0003011_delayed_dark_adaptation0.70427563
91MP0002429_abnormal_blood_cell0.69400614
92MP0005410_abnormal_fertilization0.68680057
93MP0008469_abnormal_protein_level0.68487788
94MP0001501_abnormal_sleep_pattern0.67610981
95MP0002095_abnormal_skin_pigmentation0.65630328
96MP0001929_abnormal_gametogenesis0.63272309
97MP0005423_abnormal_somatic_nervous0.62823805
98MP0003880_abnormal_central_pattern0.62729524
99MP0002572_abnormal_emotion/affect_behav0.62637080
100MP0002876_abnormal_thyroid_physiology0.61290656

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)6.70321217
2Acute necrotizing encephalopathy (HP:0006965)5.07141810
3Abnormal mitochondria in muscle tissue (HP:0008316)4.59111862
4Pendular nystagmus (HP:0012043)4.50592692
5Abnormal rod and cone electroretinograms (HP:0008323)4.46084506
6Acute encephalopathy (HP:0006846)4.22691910
7Decreased central vision (HP:0007663)4.21329511
8Mitochondrial inheritance (HP:0001427)4.15936075
9Progressive macrocephaly (HP:0004481)4.15474033
10Reticulocytopenia (HP:0001896)4.14721445
11Elevated erythrocyte sedimentation rate (HP:0003565)3.91528787
12Increased hepatocellular lipid droplets (HP:0006565)3.78495319
13Lipid accumulation in hepatocytes (HP:0006561)3.55287231
14Increased CSF lactate (HP:0002490)3.51094897
15Renal Fanconi syndrome (HP:0001994)3.47489947
16Increased intramyocellular lipid droplets (HP:0012240)3.38249780
17Congenital, generalized hypertrichosis (HP:0004540)3.36193977
18Optic disc pallor (HP:0000543)3.35970098
19Cerebral edema (HP:0002181)3.10940850
20Abnormality of cells of the erythroid lineage (HP:0012130)3.07172281
21Keratoconus (HP:0000563)3.06904036
22Increased corneal curvature (HP:0100692)3.06904036
23Molar tooth sign on MRI (HP:0002419)3.03656563
24Abnormality of midbrain morphology (HP:0002418)3.03656563
25Hepatocellular necrosis (HP:0001404)2.97073468
263-Methylglutaconic aciduria (HP:0003535)2.95666661
27Pancreatic cysts (HP:0001737)2.94441487
28Dynein arm defect of respiratory motile cilia (HP:0012255)2.92497551
29Absent/shortened dynein arms (HP:0200106)2.92497551
30Increased muscle lipid content (HP:0009058)2.85753363
31Attenuation of retinal blood vessels (HP:0007843)2.82112746
32Pallor (HP:0000980)2.79639458
33Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.64549731
34Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.63091478
35Exertional dyspnea (HP:0002875)2.57690457
36Macrocytic anemia (HP:0001972)2.57397895
37Abnormality of alanine metabolism (HP:0010916)2.57131762
38Hyperalaninemia (HP:0003348)2.57131762
39Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.57131762
40Abnormal ciliary motility (HP:0012262)2.56976657
41Medial flaring of the eyebrow (HP:0010747)2.56828170
42Absent thumb (HP:0009777)2.52192617
43Aplasia/Hypoplasia of the sacrum (HP:0008517)2.50305448
44Posterior subcapsular cataract (HP:0007787)2.50161158
45Aplasia/Hypoplasia of the spleen (HP:0010451)2.48330008
46Aplastic anemia (HP:0001915)2.47914235
47Hypoplasia of the uterus (HP:0000013)2.46809809
48Self-mutilation (HP:0000742)2.41999395
49Acanthocytosis (HP:0001927)2.41406453
50IgG deficiency (HP:0004315)2.36810877
51Abnormal number of erythroid precursors (HP:0012131)2.36227450
52Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.35230429
53Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.34621171
54Abnormal respiratory epithelium morphology (HP:0012253)2.32787988
55Abnormal respiratory motile cilium morphology (HP:0005938)2.32787988
56Asplenia (HP:0001746)2.29649614
57Abnormal respiratory motile cilium physiology (HP:0012261)2.29168364
58Hepatic necrosis (HP:0002605)2.27334521
59Disinhibition (HP:0000734)2.26553537
60Leukodystrophy (HP:0002415)2.26381684
61Pancreatic fibrosis (HP:0100732)2.24934079
62Spastic paraparesis (HP:0002313)2.24509779
63Abnormality of renal resorption (HP:0011038)2.18339014
64Increased serum lactate (HP:0002151)2.13876167
65Dyskinesia (HP:0100660)2.11967457
66Aplasia/hypoplasia of the uterus (HP:0008684)2.09855530
67Exercise intolerance (HP:0003546)2.05575028
68X-linked dominant inheritance (HP:0001423)2.04557755
69Unsteady gait (HP:0002317)2.04181863
70Hyperphosphaturia (HP:0003109)2.03852265
71Cerebral hypomyelination (HP:0006808)2.02057839
72Recurrent sinusitis (HP:0011108)2.01122809
73Respiratory failure (HP:0002878)1.99155868
74Microretrognathia (HP:0000308)1.98377048
75Agitation (HP:0000713)1.97145780
76Hypothermia (HP:0002045)1.92402315
77Gastrointestinal infarctions (HP:0005244)1.92352990
78Lactic acidosis (HP:0003128)1.91017716
79Cystic liver disease (HP:0006706)1.88734281
80Abnormality of urine glucose concentration (HP:0011016)1.87557507
81Glycosuria (HP:0003076)1.87557507
82Carpal bone hypoplasia (HP:0001498)1.87355918
83Irregular epiphyses (HP:0010582)1.85446896
84Personality changes (HP:0000751)1.84610853
85Nephrogenic diabetes insipidus (HP:0009806)1.83219671
86Chronic bronchitis (HP:0004469)1.82386081
87Congenital stationary night blindness (HP:0007642)1.82044632
88Colon cancer (HP:0003003)1.81256506
89Woolly hair (HP:0002224)1.79458626
90Porencephaly (HP:0002132)1.78082976
91Parakeratosis (HP:0001036)1.74339783
92Anencephaly (HP:0002323)1.74062191
93Oligomenorrhea (HP:0000876)1.70587331
94Bifid tongue (HP:0010297)1.70554539
95Gait imbalance (HP:0002141)1.70387579
96Vasculitis (HP:0002633)1.70237455
97Rhinitis (HP:0012384)1.69961479
98Sclerocornea (HP:0000647)1.69110464
99Lethargy (HP:0001254)1.67743861
100Abnormal biliary tract physiology (HP:0012439)1.67667491

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.50214179
2TXK3.87186818
3NUAK13.36421647
4MAP4K12.85634181
5TAOK32.79007683
6TLK12.64665108
7BMPR22.57911188
8CDK192.08287839
9ZAK2.03466809
10FES1.89790498
11ADRBK21.87129474
12MAP3K121.86811557
13STK161.86039717
14GRK11.79866492
15BCKDK1.73085790
16TIE11.60185791
17VRK21.55666083
18KDR1.52259071
19GRK71.47302463
20LIMK11.47010274
21FRK1.46437825
22WNK31.35754775
23MYLK1.34632914
24GRK61.32905605
25WNK41.32135303
26RIPK41.27642740
27IKBKB1.19509437
28MAP3K111.16500843
29TNK21.14674340
30OXSR11.14481189
31VRK11.11138271
32PHKG11.09073531
33PHKG21.09073531
34DAPK31.07096931
35BTK1.06106836
36PRKCG1.05913834
37PINK11.04625004
38TYRO31.02711703
39ITK0.99117195
40CSK0.97191306
41ILK0.92755011
42SYK0.91321182
43LCK0.89961917
44MAP4K20.89138848
45CDC70.86701381
46LRRK20.86662084
47ADRBK10.85615434
48INSRR0.84107024
49TEC0.83970912
50PIM10.81290888
51PRKACA0.77816011
52MST40.77490966
53PRKCH0.77490656
54PKN10.75882440
55GRK50.75457455
56LYN0.75424890
57DYRK30.74602502
58PLK30.71030962
59PRKCQ0.69725426
60BMPR1B0.69109726
61CSNK2A20.67746442
62CDK80.67285945
63PIK3CA0.66877882
64MAPK130.63834999
65CAMK10.63522470
66OBSCN0.61901457
67DAPK10.59944834
68STK390.58976073
69CSNK2A10.58748391
70PRKCA0.58247637
71RPS6KA60.58237165
72CSF1R0.54717792
73ABL20.54379510
74PASK0.51621888
75PLK10.50119415
76MATK0.50112584
77PRKACG0.48626903
78EIF2AK10.48216716
79NME10.47850476
80CAMK2A0.47633988
81TRIM280.47235901
82EPHB20.46169566
83NTRK20.46083897
84SRPK10.45493083
85AURKA0.45266501
86PRKG10.45013621
87TESK20.42986969
88STK240.40307577
89PRKCD0.40101669
90MKNK20.39937616
91AURKB0.39427224
92MAPK150.39280287
93PIK3CG0.36773284
94MAP3K40.36548713
95DYRK20.36201197
96CSNK1A10.35762308
97RPS6KC10.35394507
98RPS6KL10.35394507
99MAP3K60.34618380
100ROCK10.32656857

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.88402297
2Oxidative phosphorylation_Homo sapiens_hsa001904.25306085
3Parkinsons disease_Homo sapiens_hsa050123.44372598
4Protein export_Homo sapiens_hsa030602.68622479
5Asthma_Homo sapiens_hsa053102.59202926
6Intestinal immune network for IgA production_Homo sapiens_hsa046722.55856506
7RNA polymerase_Homo sapiens_hsa030202.50641572
8Autoimmune thyroid disease_Homo sapiens_hsa053202.46516849
9Alzheimers disease_Homo sapiens_hsa050102.42498753
10Cardiac muscle contraction_Homo sapiens_hsa042602.38626381
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.38519152
12Proteasome_Homo sapiens_hsa030502.38131450
13Allograft rejection_Homo sapiens_hsa053302.35640117
14Huntingtons disease_Homo sapiens_hsa050162.26731547
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.07405446
16RNA degradation_Homo sapiens_hsa030182.02213647
17Graft-versus-host disease_Homo sapiens_hsa053321.89166654
18Primary immunodeficiency_Homo sapiens_hsa053401.86221960
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.69721470
20Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.66139166
21Sulfur relay system_Homo sapiens_hsa041221.64430915
22Mismatch repair_Homo sapiens_hsa034301.53834650
23Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.53187992
24Type I diabetes mellitus_Homo sapiens_hsa049401.48237886
25Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.38775780
26DNA replication_Homo sapiens_hsa030301.28128240
27Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.24051264
28Phototransduction_Homo sapiens_hsa047441.10963863
29Caffeine metabolism_Homo sapiens_hsa002321.10656116
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.08875604
31Fatty acid biosynthesis_Homo sapiens_hsa000611.07992590
32Hematopoietic cell lineage_Homo sapiens_hsa046401.07491027
33Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.04455147
34Linoleic acid metabolism_Homo sapiens_hsa005911.03894466
35Pyrimidine metabolism_Homo sapiens_hsa002400.96271667
36Homologous recombination_Homo sapiens_hsa034400.94627214
37One carbon pool by folate_Homo sapiens_hsa006700.92213678
38Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88824463
39Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.88306033
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.88107925
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.87618156
42Olfactory transduction_Homo sapiens_hsa047400.86736479
43Steroid hormone biosynthesis_Homo sapiens_hsa001400.84942550
44Antigen processing and presentation_Homo sapiens_hsa046120.83769470
45Chemical carcinogenesis_Homo sapiens_hsa052040.82507260
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.79235261
47T cell receptor signaling pathway_Homo sapiens_hsa046600.78311488
48Rheumatoid arthritis_Homo sapiens_hsa053230.77976386
49Tryptophan metabolism_Homo sapiens_hsa003800.77856168
50Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76361916
51Nucleotide excision repair_Homo sapiens_hsa034200.74880577
52Purine metabolism_Homo sapiens_hsa002300.74824834
53Spliceosome_Homo sapiens_hsa030400.73944839
54Basal transcription factors_Homo sapiens_hsa030220.70002588
55Viral myocarditis_Homo sapiens_hsa054160.67374253
56Primary bile acid biosynthesis_Homo sapiens_hsa001200.67058897
57Fanconi anemia pathway_Homo sapiens_hsa034600.67007293
58Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.65364767
59Sulfur metabolism_Homo sapiens_hsa009200.64270555
60Retinol metabolism_Homo sapiens_hsa008300.60850583
61Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59725038
62Nitrogen metabolism_Homo sapiens_hsa009100.58734719
63Nicotine addiction_Homo sapiens_hsa050330.57717836
64Metabolic pathways_Homo sapiens_hsa011000.53764081
65Base excision repair_Homo sapiens_hsa034100.53430737
66RNA transport_Homo sapiens_hsa030130.52118289
67Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.50663752
68Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.50025753
69Staphylococcus aureus infection_Homo sapiens_hsa051500.49316214
70ABC transporters_Homo sapiens_hsa020100.48369756
71Arachidonic acid metabolism_Homo sapiens_hsa005900.48215555
72Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48173295
73NF-kappa B signaling pathway_Homo sapiens_hsa040640.47878958
74SNARE interactions in vesicular transport_Homo sapiens_hsa041300.47620499
75Fatty acid elongation_Homo sapiens_hsa000620.47111645
76Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46630423
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.46226079
78Tyrosine metabolism_Homo sapiens_hsa003500.42465543
79Peroxisome_Homo sapiens_hsa041460.40660543
80Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39627055
81Drug metabolism - other enzymes_Homo sapiens_hsa009830.35855082
82NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31786443
83Systemic lupus erythematosus_Homo sapiens_hsa053220.31741654
84Fatty acid degradation_Homo sapiens_hsa000710.31351205
85Cysteine and methionine metabolism_Homo sapiens_hsa002700.31000058
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.28972128
87Morphine addiction_Homo sapiens_hsa050320.27690195
88Mineral absorption_Homo sapiens_hsa049780.27341923
89Salivary secretion_Homo sapiens_hsa049700.25711542
90Glycerolipid metabolism_Homo sapiens_hsa005610.25249689
91Fatty acid metabolism_Homo sapiens_hsa012120.24945111
92Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.23766116
93Amphetamine addiction_Homo sapiens_hsa050310.23558302
94Propanoate metabolism_Homo sapiens_hsa006400.21441648
95Insulin secretion_Homo sapiens_hsa049110.19324496
96Pentose and glucuronate interconversions_Homo sapiens_hsa000400.17123370
97Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.15204284
98Fat digestion and absorption_Homo sapiens_hsa049750.13532756
99Glycerophospholipid metabolism_Homo sapiens_hsa005640.12702993
100Taste transduction_Homo sapiens_hsa047420.12109423

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