Rank | Gene Set | Z-score |
---|---|---|
1 | * translational termination (GO:0006415) | 9.98828042 |
2 | ribosomal small subunit assembly (GO:0000028) | 9.49926598 |
3 | * translational elongation (GO:0006414) | 8.43875169 |
4 | * ribosomal small subunit biogenesis (GO:0042274) | 8.39925517 |
5 | * SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 8.31713483 |
6 | * protein targeting to ER (GO:0045047) | 8.15399520 |
7 | * cotranslational protein targeting to membrane (GO:0006613) | 8.14621221 |
8 | * nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 7.87926497 |
9 | * establishment of protein localization to endoplasmic reticulum (GO:0072599) | 7.81512431 |
10 | * cellular protein complex disassembly (GO:0043624) | 7.69414353 |
11 | * viral life cycle (GO:0019058) | 7.68848221 |
12 | * protein localization to endoplasmic reticulum (GO:0070972) | 7.58407955 |
13 | * translational initiation (GO:0006413) | 7.26963840 |
14 | ribosomal large subunit biogenesis (GO:0042273) | 6.84038440 |
15 | * protein complex disassembly (GO:0043241) | 6.77609345 |
16 | * maturation of SSU-rRNA (GO:0030490) | 6.55158921 |
17 | * macromolecular complex disassembly (GO:0032984) | 6.30860900 |
18 | * nuclear-transcribed mRNA catabolic process (GO:0000956) | 5.58459682 |
19 | * protein targeting to membrane (GO:0006612) | 5.46106532 |
20 | * mRNA catabolic process (GO:0006402) | 5.30643332 |
21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.13423177 |
22 | * RNA catabolic process (GO:0006401) | 4.95243713 |
23 | ATP synthesis coupled proton transport (GO:0015986) | 4.81113199 |
24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.81113199 |
25 | * translation (GO:0006412) | 4.73885634 |
26 | * ribonucleoprotein complex biogenesis (GO:0022613) | 4.62524606 |
27 | formation of translation preinitiation complex (GO:0001731) | 4.02884242 |
28 | * rRNA processing (GO:0006364) | 3.69232360 |
29 | regulation of translational fidelity (GO:0006450) | 3.63652990 |
30 | * establishment of protein localization to membrane (GO:0090150) | 3.62717745 |
31 | * rRNA metabolic process (GO:0016072) | 3.58115069 |
32 | ncRNA 3-end processing (GO:0043628) | 3.52836874 |
33 | DNA unwinding involved in DNA replication (GO:0006268) | 3.45486624 |
34 | negative regulation of RNA splicing (GO:0033119) | 3.32900872 |
35 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.29615255 |
36 | * establishment of protein localization to organelle (GO:0072594) | 3.29526674 |
37 | oxidative phosphorylation (GO:0006119) | 3.24116697 |
38 | * protein targeting (GO:0006605) | 3.21558679 |
39 | * cellular component biogenesis (GO:0044085) | 3.17945123 |
40 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.17790267 |
41 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.16958416 |
42 | DNA strand elongation (GO:0022616) | 3.10440210 |
43 | respiratory electron transport chain (GO:0022904) | 3.09490179 |
44 | electron transport chain (GO:0022900) | 3.02521454 |
45 | DNA deamination (GO:0045006) | 2.95600114 |
46 | heterochromatin organization (GO:0070828) | 2.90524457 |
47 | * cellular component disassembly (GO:0022411) | 2.87393747 |
48 | DNA replication initiation (GO:0006270) | 2.84484507 |
49 | viral protein processing (GO:0019082) | 2.80092140 |
50 | protein localization to kinetochore (GO:0034501) | 2.79039068 |
51 | telomere maintenance via recombination (GO:0000722) | 2.75306141 |
52 | mitotic recombination (GO:0006312) | 2.74784902 |
53 | spliceosomal complex assembly (GO:0000245) | 2.74141917 |
54 | * protein localization to membrane (GO:0072657) | 2.73717145 |
55 | spliceosomal snRNP assembly (GO:0000387) | 2.72504360 |
56 | histone H2B ubiquitination (GO:0033523) | 2.66738354 |
57 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.64523667 |
58 | chaperone-mediated protein transport (GO:0072321) | 2.64020044 |
59 | * gene expression (GO:0010467) | 2.60220098 |
60 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.58433264 |
61 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.57740615 |
62 | establishment of integrated proviral latency (GO:0075713) | 2.57107457 |
63 | ATP biosynthetic process (GO:0006754) | 2.53992984 |
64 | kinetochore organization (GO:0051383) | 2.53766096 |
65 | protein localization to chromosome, centromeric region (GO:0071459) | 2.53591152 |
66 | chromatin remodeling at centromere (GO:0031055) | 2.53122454 |
67 | inner mitochondrial membrane organization (GO:0007007) | 2.52714251 |
68 | telomere maintenance via telomere lengthening (GO:0010833) | 2.51689497 |
69 | mitotic nuclear envelope disassembly (GO:0007077) | 2.51659293 |
70 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.51426195 |
71 | mRNA splicing, via spliceosome (GO:0000398) | 2.51426195 |
72 | regulation of protein heterodimerization activity (GO:0043497) | 2.51082227 |
73 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.50345399 |
74 | ribosome biogenesis (GO:0042254) | 2.50142507 |
75 | RNA splicing, via transesterification reactions (GO:0000375) | 2.49612625 |
76 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.49239165 |
77 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.49239165 |
78 | ribosome assembly (GO:0042255) | 2.48534497 |
79 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.47755723 |
80 | * protein localization to organelle (GO:0033365) | 2.47185769 |
81 | CENP-A containing nucleosome assembly (GO:0034080) | 2.46686673 |
82 | regulation of histone H3-K9 methylation (GO:0051570) | 2.46043423 |
83 | ribonucleoprotein complex assembly (GO:0022618) | 2.45420846 |
84 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.44959568 |
85 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.44959568 |
86 | termination of RNA polymerase II transcription (GO:0006369) | 2.44819389 |
87 | * ncRNA processing (GO:0034470) | 2.40422472 |
88 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.40421010 |
89 | DNA replication-independent nucleosome organization (GO:0034724) | 2.40421010 |
90 | nuclear pore organization (GO:0006999) | 2.36248508 |
91 | pseudouridine synthesis (GO:0001522) | 2.35887638 |
92 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.35695482 |
93 | histone mRNA metabolic process (GO:0008334) | 2.35170818 |
94 | negative regulation of mRNA processing (GO:0050686) | 2.34012958 |
95 | membrane disassembly (GO:0030397) | 2.32433658 |
96 | nuclear envelope disassembly (GO:0051081) | 2.32433658 |
97 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.32303917 |
98 | nuclear pore complex assembly (GO:0051292) | 2.31822676 |
99 | DNA replication checkpoint (GO:0000076) | 2.31683795 |
100 | interferon-gamma secretion (GO:0072643) | 2.31575280 |
101 | regulation of RNA export from nucleus (GO:0046831) | 2.30939333 |
102 | ribonucleoprotein complex subunit organization (GO:0071826) | 2.30892459 |
103 | aerobic respiration (GO:0009060) | 2.30828257 |
104 | * single-organism cellular localization (GO:1902580) | 2.28169703 |
105 | mitotic chromosome condensation (GO:0007076) | 2.27949964 |
106 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.27440469 |
107 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.27378462 |
108 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.25565503 |
109 | regulation of mitochondrial translation (GO:0070129) | 2.24400947 |
110 | chromosome condensation (GO:0030261) | 2.24385996 |
111 | pore complex assembly (GO:0046931) | 2.24237426 |
112 | mitotic sister chromatid segregation (GO:0000070) | 2.23991973 |
113 | sister chromatid segregation (GO:0000819) | 2.23337388 |
114 | chaperone-mediated protein complex assembly (GO:0051131) | 2.22602171 |
115 | DNA duplex unwinding (GO:0032508) | 2.22578222 |
116 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.19998951 |
117 | DNA geometric change (GO:0032392) | 2.19970912 |
118 | DNA topological change (GO:0006265) | 2.19137147 |
119 | * ncRNA metabolic process (GO:0034660) | 2.18807088 |
120 | negative regulation of translational initiation (GO:0045947) | 2.18600473 |
121 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.17600204 |
122 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.17600204 |
123 | chromatin assembly (GO:0031497) | 2.16525979 |
124 | chromatin assembly or disassembly (GO:0006333) | 2.16127498 |
125 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.15756062 |
126 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.15027447 |
127 | regulation of translational initiation (GO:0006446) | 2.14398715 |
128 | DNA-templated transcription, termination (GO:0006353) | 2.12969693 |
129 | nucleobase biosynthetic process (GO:0046112) | 2.12324716 |
130 | kinetochore assembly (GO:0051382) | 2.11629125 |
131 | negative regulation of mRNA metabolic process (GO:1903312) | 2.11547267 |
132 | mitotic metaphase plate congression (GO:0007080) | 2.11416069 |
133 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.11386822 |
134 | * viral transcription (GO:0019083) | 10.4051609 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.92422335 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.60170466 |
3 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.74379852 |
4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.70259586 |
5 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.52772549 |
6 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 3.37462604 |
7 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.34655314 |
8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.09677530 |
9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.76241677 |
10 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.73121612 |
11 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.64472008 |
12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.61349743 |
13 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.59323907 |
14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.56503423 |
15 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.54435303 |
16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.24661216 |
17 | MYC_22102868_ChIP-Seq_BL_Human | 2.21489631 |
18 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.18759888 |
19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.18452095 |
20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.14291869 |
21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.13991238 |
22 | * TTF2_22483619_ChIP-Seq_HELA_Human | 2.12704913 |
23 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.10838306 |
24 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.09058008 |
25 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.08903107 |
26 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.07788586 |
27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.06388328 |
28 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.05145728 |
29 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.02444937 |
30 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.99060422 |
31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.86774755 |
32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.85057499 |
33 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 1.83459521 |
34 | * DCP1A_22483619_ChIP-Seq_HELA_Human | 1.78743805 |
35 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.75396398 |
36 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.69027376 |
37 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.68448708 |
38 | * E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.57938193 |
39 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.55425951 |
40 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.52735438 |
41 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.51633952 |
42 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.44750879 |
43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.43785240 |
44 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.40866785 |
45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39611307 |
46 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.39163840 |
47 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.38605578 |
48 | * ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.36952907 |
49 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.36623351 |
50 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.36497375 |
51 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.36412263 |
52 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.35683539 |
53 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.35464280 |
54 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.32325033 |
55 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.31411515 |
56 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.30105998 |
57 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.30007113 |
58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.26502560 |
59 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.25343682 |
60 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.24907966 |
61 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.24747070 |
62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.24257771 |
63 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.23692560 |
64 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.22828899 |
65 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.22639452 |
66 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.18236755 |
67 | UTX_26944678_Chip-Seq_JUKART_Human | 1.18013109 |
68 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.17190492 |
69 | MAF_26560356_Chip-Seq_TH1_Human | 1.15193211 |
70 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.14282090 |
71 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.13093310 |
72 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.12776547 |
73 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.11678824 |
74 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.09824863 |
75 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.07910364 |
76 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.07680457 |
77 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.07533844 |
78 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.07201927 |
79 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.07199574 |
80 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.06898684 |
81 | MYB_26560356_Chip-Seq_TH2_Human | 1.05308810 |
82 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.05250238 |
83 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.04953793 |
84 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.03742896 |
85 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.03027502 |
86 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.02897340 |
87 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.02393848 |
88 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.01984904 |
89 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01391319 |
90 | MAF_26560356_Chip-Seq_TH2_Human | 1.00266454 |
91 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.00216906 |
92 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.99442738 |
93 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.99381578 |
94 | * CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.98736539 |
95 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.98453708 |
96 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.98341746 |
97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.97910717 |
98 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.96330093 |
99 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.95769508 |
100 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.95628918 |
101 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.95521278 |
102 | ZNF263_19887448_ChIP-Seq_K562_Human | 0.95498573 |
103 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.95294099 |
104 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.95259104 |
105 | MYB_26560356_Chip-Seq_TH1_Human | 0.94960969 |
106 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.94363479 |
107 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.94167420 |
108 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.94055063 |
109 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.93941220 |
110 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.93240736 |
111 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.92644837 |
112 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.92299225 |
113 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.91688590 |
114 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.91200088 |
115 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.90814559 |
116 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.90589744 |
117 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.90502448 |
118 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.90304597 |
119 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.90166363 |
120 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.89936358 |
121 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.88289324 |
122 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.85846353 |
123 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.85036790 |
124 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.85036790 |
125 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.85036790 |
126 | * TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.83352014 |
127 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.81637748 |
128 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.81292895 |
129 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.80243522 |
130 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.79192120 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 4.37236602 |
2 | MP0006292_abnormal_olfactory_placode | 4.31378112 |
3 | MP0003693_abnormal_embryo_hatching | 3.80769908 |
4 | MP0004957_abnormal_blastocyst_morpholog | 3.35487864 |
5 | MP0000566_synostosis | 3.08331102 |
6 | MP0010094_abnormal_chromosome_stability | 2.71945428 |
7 | MP0003077_abnormal_cell_cycle | 2.58833089 |
8 | MP0003111_abnormal_nucleus_morphology | 2.45019795 |
9 | MP0010352_gastrointestinal_tract_polyps | 2.41138020 |
10 | MP0002396_abnormal_hematopoietic_system | 2.38053545 |
11 | MP0003763_abnormal_thymus_physiology | 2.16875241 |
12 | MP0000490_abnormal_crypts_of | 1.99829848 |
13 | MP0008057_abnormal_DNA_replication | 1.97945055 |
14 | MP0008007_abnormal_cellular_replicative | 1.91933425 |
15 | MP0002166_altered_tumor_susceptibility | 1.86059963 |
16 | MP0004808_abnormal_hematopoietic_stem | 1.69939194 |
17 | MP0002938_white_spotting | 1.67959652 |
18 | MP0002697_abnormal_eye_size | 1.66151100 |
19 | MP0008932_abnormal_embryonic_tissue | 1.64619788 |
20 | MP0009333_abnormal_splenocyte_physiolog | 1.63749572 |
21 | MP0000350_abnormal_cell_proliferation | 1.58251042 |
22 | MP0001286_abnormal_eye_development | 1.57263435 |
23 | MP0008058_abnormal_DNA_repair | 1.56965700 |
24 | MP0008789_abnormal_olfactory_epithelium | 1.52904245 |
25 | MP0004381_abnormal_hair_follicle | 1.51804887 |
26 | MP0003567_abnormal_fetal_cardiomyocyte | 1.51465101 |
27 | MP0000685_abnormal_immune_system | 1.50555231 |
28 | MP0002006_tumorigenesis | 1.50034149 |
29 | MP0002398_abnormal_bone_marrow | 1.49617253 |
30 | MP0002234_abnormal_pharynx_morphology | 1.48869055 |
31 | MP0002796_impaired_skin_barrier | 1.48408570 |
32 | MP0000703_abnormal_thymus_morphology | 1.48130613 |
33 | MP0003890_abnormal_embryonic-extraembry | 1.47305911 |
34 | MP0003941_abnormal_skin_development | 1.46851539 |
35 | MP0001800_abnormal_humoral_immune | 1.46116733 |
36 | MP0001730_embryonic_growth_arrest | 1.45057440 |
37 | MP0003786_premature_aging | 1.43381667 |
38 | MP0006054_spinal_hemorrhage | 1.42334450 |
39 | MP0004185_abnormal_adipocyte_glucose | 1.41429684 |
40 | MP0000049_abnormal_middle_ear | 1.40515165 |
41 | MP0003937_abnormal_limbs/digits/tail_de | 1.38116390 |
42 | MP0001835_abnormal_antigen_presentation | 1.36344099 |
43 | MP0002722_abnormal_immune_system | 1.35323333 |
44 | MP0005501_abnormal_skin_physiology | 1.34358913 |
45 | MP0000762_abnormal_tongue_morphology | 1.34031561 |
46 | MP0002653_abnormal_ependyma_morphology | 1.33979934 |
47 | MP0002009_preneoplasia | 1.33205900 |
48 | MP0005499_abnormal_olfactory_system | 1.33146844 |
49 | MP0005394_taste/olfaction_phenotype | 1.33146844 |
50 | MP0002249_abnormal_larynx_morphology | 1.33143099 |
51 | MP0002092_abnormal_eye_morphology | 1.32873689 |
52 | MP0003123_paternal_imprinting | 1.31137416 |
53 | MP0005174_abnormal_tail_pigmentation | 1.29970200 |
54 | MP0010234_abnormal_vibrissa_follicle | 1.28872983 |
55 | MP0002019_abnormal_tumor_incidence | 1.27720488 |
56 | MP0001873_stomach_inflammation | 1.27218210 |
57 | MP0010155_abnormal_intestine_physiology | 1.27030098 |
58 | MP0000465_gastrointestinal_hemorrhage | 1.25685929 |
59 | MP0001545_abnormal_hematopoietic_system | 1.24290389 |
60 | MP0005397_hematopoietic_system_phenotyp | 1.24290389 |
61 | MP0002420_abnormal_adaptive_immunity | 1.20604336 |
62 | MP0003942_abnormal_urinary_system | 1.20485369 |
63 | MP0000537_abnormal_urethra_morphology | 1.19945453 |
64 | MP0003300_gastrointestinal_ulcer | 1.19671339 |
65 | MP0003186_abnormal_redox_activity | 1.19617262 |
66 | MP0000689_abnormal_spleen_morphology | 1.18692590 |
67 | MP0002452_abnormal_antigen_presenting | 1.18292255 |
68 | MP0001819_abnormal_immune_cell | 1.17368938 |
69 | MP0010307_abnormal_tumor_latency | 1.16990857 |
70 | MP0005076_abnormal_cell_differentiation | 1.16922355 |
71 | MP0000428_abnormal_craniofacial_morphol | 1.16805274 |
72 | MP0005671_abnormal_response_to | 1.15606309 |
73 | MP0000858_altered_metastatic_potential | 1.15407086 |
74 | MP0001216_abnormal_epidermal_layer | 1.15249018 |
75 | MP0000716_abnormal_immune_system | 1.15107247 |
76 | MP0002429_abnormal_blood_cell | 1.14275395 |
77 | MP0001697_abnormal_embryo_size | 1.13963361 |
78 | MP0001346_abnormal_lacrimal_gland | 1.13927360 |
79 | MP0003122_maternal_imprinting | 1.13200710 |
80 | MP0002163_abnormal_gland_morphology | 1.13198414 |
81 | MP0002160_abnormal_reproductive_system | 1.12546713 |
82 | MP0003938_abnormal_ear_development | 1.11468959 |
83 | MP0002060_abnormal_skin_morphology | 1.11354897 |
84 | MP0002405_respiratory_system_inflammati | 1.09707422 |
85 | MP0002080_prenatal_lethality | 1.09567396 |
86 | MP0003121_genomic_imprinting | 1.09052327 |
87 | MP0003315_abnormal_perineum_morphology | 1.08888291 |
88 | MP0002233_abnormal_nose_morphology | 1.08219493 |
89 | MP0000313_abnormal_cell_death | 1.06997814 |
90 | MP0002210_abnormal_sex_determination | 1.06738840 |
91 | MP0001853_heart_inflammation | 1.05631724 |
92 | MP0000383_abnormal_hair_follicle | 1.05485857 |
93 | MP0003453_abnormal_keratinocyte_physiol | 1.05381681 |
94 | MP0002723_abnormal_immune_serum | 1.05308791 |
95 | MP0002084_abnormal_developmental_patter | 1.05244838 |
96 | MP0002095_abnormal_skin_pigmentation | 1.05208502 |
97 | MP0002086_abnormal_extraembryonic_tissu | 1.04198824 |
98 | MP0005023_abnormal_wound_healing | 1.03376086 |
99 | MP0004197_abnormal_fetal_growth/weight/ | 1.02998557 |
100 | MP0005380_embryogenesis_phenotype | 1.02892440 |
101 | MP0001672_abnormal_embryogenesis/_devel | 1.02892440 |
102 | MP0003436_decreased_susceptibility_to | 1.02291604 |
103 | MP0002085_abnormal_embryonic_tissue | 1.02086925 |
104 | MP0005000_abnormal_immune_tolerance | 1.02074467 |
105 | MP0002111_abnormal_tail_morphology | 1.01799808 |
106 | MP0003566_abnormal_cell_adhesion | 1.01445004 |
107 | MP0004947_skin_inflammation | 0.97696360 |
108 | MP0003861_abnormal_nervous_system | 0.97525664 |
109 | MP0003866_abnormal_defecation | 0.97476599 |
110 | MP0000631_abnormal_neuroendocrine_gland | 0.96530800 |
111 | MP0002098_abnormal_vibrissa_morphology | 0.96389215 |
112 | MP0003755_abnormal_palate_morphology | 0.96279010 |
113 | MP0001485_abnormal_pinna_reflex | 0.95767082 |
114 | MP0000377_abnormal_hair_follicle | 0.95188049 |
115 | MP0003718_maternal_effect | 0.94924893 |
116 | MP0002088_abnormal_embryonic_growth/wei | 0.94790492 |
117 | MP0005025_abnormal_response_to | 0.93868846 |
118 | MP0003984_embryonic_growth_retardation | 0.93766129 |
119 | MP0002132_abnormal_respiratory_system | 0.93112805 |
120 | MP0009278_abnormal_bone_marrow | 0.93013088 |
121 | MP0000477_abnormal_intestine_morphology | 0.91466497 |
122 | MP0001790_abnormal_immune_system | 0.89246923 |
123 | MP0005387_immune_system_phenotype | 0.89246923 |
124 | MP0003136_yellow_coat_color | 0.87827222 |
125 | MP0009053_abnormal_anal_canal | 0.87396788 |
126 | MP0010030_abnormal_orbit_morphology | 0.85617090 |
127 | MP0002116_abnormal_craniofacial_bone | 0.84063789 |
128 | MP0000778_abnormal_nervous_system | 0.82913716 |
129 | MP0004142_abnormal_muscle_tone | 0.81774442 |
130 | MP0010678_abnormal_skin_adnexa | 0.81399013 |
131 | MP0000534_abnormal_ureter_morphology | 0.79153450 |
132 | MP0001727_abnormal_embryo_implantation | 0.78970577 |
133 | MP0003935_abnormal_craniofacial_develop | 0.78371197 |
134 | MP0005408_hypopigmentation | 0.78337212 |
135 | MP0001145_abnormal_male_reproductive | 0.78227122 |
136 | MP0009931_abnormal_skin_appearance | 0.78019282 |
137 | MP0009785_altered_susceptibility_to | 0.77660153 |
138 | MP0003303_peritoneal_inflammation | 0.77514659 |
139 | MP0003787_abnormal_imprinting | 0.77206220 |
140 | MP0008995_early_reproductive_senescence | 0.77060217 |
141 | MP0001293_anophthalmia | 0.77049835 |
142 | MP0009672_abnormal_birth_weight | 0.76755589 |
143 | MP0009250_abnormal_appendicular_skeleto | 0.76659922 |
144 | MP0001529_abnormal_vocalization | 0.76255280 |
145 | MP0003448_altered_tumor_morphology | 0.74586447 |
146 | MP0005075_abnormal_melanosome_morpholog | 0.73750669 |
147 | MP0004742_abnormal_vestibular_system | 0.70717864 |
148 | MP0000678_abnormal_parathyroid_gland | 0.69383052 |
149 | MP0005391_vision/eye_phenotype | 0.69244750 |
150 | MP0001929_abnormal_gametogenesis | 0.68954574 |
151 | MP0002932_abnormal_joint_morphology | 0.67873012 |
152 | MP0005389_reproductive_system_phenotype | 0.67788360 |
153 | MP0000026_abnormal_inner_ear | 0.66822475 |
154 | MP0003385_abnormal_body_wall | 0.66486327 |
155 | MP0002114_abnormal_axial_skeleton | 0.65305378 |
156 | MP0001340_abnormal_eyelid_morphology | 0.64216756 |
157 | MP0000432_abnormal_head_morphology | 0.62570503 |
158 | MP0000653_abnormal_sex_gland | 0.61190335 |
159 | MP0000955_abnormal_spinal_cord | 0.60792193 |
160 | MP0001881_abnormal_mammary_gland | 0.60250332 |
161 | MP0005195_abnormal_posterior_eye | 0.60127049 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 9.38545887 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 8.18828359 |
3 | * Reticulocytopenia (HP:0001896) | 6.82744457 |
4 | * Macrocytic anemia (HP:0001972) | 5.86564459 |
5 | * Pallor (HP:0000980) | 5.47650838 |
6 | Partial duplication of thumb phalanx (HP:0009944) | 4.65723701 |
7 | Thrombocytosis (HP:0001894) | 4.15190295 |
8 | Colon cancer (HP:0003003) | 3.83380201 |
9 | Duplication of thumb phalanx (HP:0009942) | 3.38635842 |
10 | Acute necrotizing encephalopathy (HP:0006965) | 3.04926312 |
11 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.03649781 |
12 | 11 pairs of ribs (HP:0000878) | 3.00050994 |
13 | Septo-optic dysplasia (HP:0100842) | 2.98788917 |
14 | Abnormality of the parietal bone (HP:0002696) | 2.90550981 |
15 | Acute encephalopathy (HP:0006846) | 2.89369519 |
16 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.87580087 |
17 | Aplastic anemia (HP:0001915) | 2.87194144 |
18 | Absent thumb (HP:0009777) | 2.86651932 |
19 | Stenosis of the external auditory canal (HP:0000402) | 2.83708849 |
20 | IgM deficiency (HP:0002850) | 2.81622574 |
21 | Congenital, generalized hypertrichosis (HP:0004540) | 2.72344494 |
22 | Trismus (HP:0000211) | 2.69268687 |
23 | Chromsome breakage (HP:0040012) | 2.67669051 |
24 | Woolly hair (HP:0002224) | 2.64634987 |
25 | Oral leukoplakia (HP:0002745) | 2.52541516 |
26 | Multiple enchondromatosis (HP:0005701) | 2.51129362 |
27 | Selective tooth agenesis (HP:0001592) | 2.50085672 |
28 | * Depressed nasal ridge (HP:0000457) | 2.50044666 |
29 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.46872206 |
30 | Basal cell carcinoma (HP:0002671) | 2.44803636 |
31 | Asplenia (HP:0001746) | 2.41868311 |
32 | Lipid accumulation in hepatocytes (HP:0006561) | 2.40417550 |
33 | Chronic otitis media (HP:0000389) | 2.37159823 |
34 | Recurrent bronchitis (HP:0002837) | 2.36391457 |
35 | Mitochondrial inheritance (HP:0001427) | 2.26094182 |
36 | * Thick lower lip vermilion (HP:0000179) | 2.25599453 |
37 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.23866365 |
38 | Missing ribs (HP:0000921) | 2.15216357 |
39 | Poikiloderma (HP:0001029) | 2.13229183 |
40 | Cerebral edema (HP:0002181) | 2.12909383 |
41 | * Migraine (HP:0002076) | 2.12861591 |
42 | Progressive macrocephaly (HP:0004481) | 2.12501372 |
43 | Impulsivity (HP:0100710) | 2.11737867 |
44 | Abnormality of the diencephalon (HP:0010662) | 2.10551785 |
45 | Rib fusion (HP:0000902) | 2.09967439 |
46 | Increased intramyocellular lipid droplets (HP:0012240) | 2.08390496 |
47 | Abnormality of DNA repair (HP:0003254) | 2.07974094 |
48 | Myelodysplasia (HP:0002863) | 2.07744829 |
49 | * Abnormality of reticulocytes (HP:0004312) | 2.05294859 |
50 | Triphalangeal thumb (HP:0001199) | 2.04384699 |
51 | Abnormality of cochlea (HP:0000375) | 2.03120463 |
52 | Proximal placement of thumb (HP:0009623) | 2.03031660 |
53 | Absent septum pellucidum (HP:0001331) | 2.02384119 |
54 | Microvesicular hepatic steatosis (HP:0001414) | 2.01883024 |
55 | Hypoplasia of the radius (HP:0002984) | 2.01685295 |
56 | Neoplasm of the pancreas (HP:0002894) | 2.00828842 |
57 | Fragile nails (HP:0001808) | 1.99846977 |
58 | Overriding aorta (HP:0002623) | 1.99670643 |
59 | Renal duplication (HP:0000075) | 1.99372267 |
60 | Increased CSF lactate (HP:0002490) | 1.98335251 |
61 | Glossoptosis (HP:0000162) | 1.98268072 |
62 | Rough bone trabeculation (HP:0100670) | 1.98205776 |
63 | Maternal diabetes (HP:0009800) | 1.96528032 |
64 | T lymphocytopenia (HP:0005403) | 1.95466006 |
65 | Atresia of the external auditory canal (HP:0000413) | 1.94861163 |
66 | Lymphoma (HP:0002665) | 1.94464058 |
67 | Abnormality of T cells (HP:0002843) | 1.93203272 |
68 | Vertebral hypoplasia (HP:0008417) | 1.91493968 |
69 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.91493968 |
70 | Nasolacrimal duct obstruction (HP:0000579) | 1.90941328 |
71 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.88104006 |
72 | Deviation of the thumb (HP:0009603) | 1.87954386 |
73 | Bicuspid aortic valve (HP:0001647) | 1.87577351 |
74 | Recurrent viral infections (HP:0004429) | 1.87341283 |
75 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.87003903 |
76 | Rectal prolapse (HP:0002035) | 1.86407076 |
77 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.85779236 |
78 | Facial cleft (HP:0002006) | 1.85710464 |
79 | Panhypogammaglobulinemia (HP:0003139) | 1.85013469 |
80 | Abnormality of the septum pellucidum (HP:0007375) | 1.84806740 |
81 | Squamous cell carcinoma (HP:0002860) | 1.83408996 |
82 | Leukodystrophy (HP:0002415) | 1.83051881 |
83 | Increased hepatocellular lipid droplets (HP:0006565) | 1.82635509 |
84 | Abnormality of the preputium (HP:0100587) | 1.81023377 |
85 | High anterior hairline (HP:0009890) | 1.80881916 |
86 | Abnormality of B cell number (HP:0010975) | 1.80879941 |
87 | B lymphocytopenia (HP:0010976) | 1.80879941 |
88 | Rectovaginal fistula (HP:0000143) | 1.80308124 |
89 | Rectal fistula (HP:0100590) | 1.80308124 |
90 | Amaurosis fugax (HP:0100576) | 1.79575788 |
91 | Breast hypoplasia (HP:0003187) | 1.79435096 |
92 | Pili torti (HP:0003777) | 1.79391602 |
93 | Pustule (HP:0200039) | 1.78734042 |
94 | Sparse lateral eyebrow (HP:0005338) | 1.77651906 |
95 | Microretrognathia (HP:0000308) | 1.77583635 |
96 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.77135674 |
97 | Cleft eyelid (HP:0000625) | 1.76326576 |
98 | Abnormality of T cell number (HP:0011839) | 1.76255561 |
99 | Elfin facies (HP:0004428) | 1.75510517 |
100 | Biliary tract neoplasm (HP:0100574) | 1.74720199 |
101 | Abnormality of T cell physiology (HP:0011840) | 1.74684852 |
102 | Abnormality of the lacrimal duct (HP:0011481) | 1.73688295 |
103 | Ependymoma (HP:0002888) | 1.73315452 |
104 | Medulloblastoma (HP:0002885) | 1.73239083 |
105 | Morphological abnormality of the inner ear (HP:0011390) | 1.73020040 |
106 | Increased nuchal translucency (HP:0010880) | 1.70694611 |
107 | Exertional dyspnea (HP:0002875) | 1.70326206 |
108 | Sparse scalp hair (HP:0002209) | 1.70264863 |
109 | Nasal polyposis (HP:0100582) | 1.69691304 |
110 | Hepatocellular necrosis (HP:0001404) | 1.68853196 |
111 | Deep palmar crease (HP:0006191) | 1.68702254 |
112 | Abnormal number of incisors (HP:0011064) | 1.68467428 |
113 | Rhabdomyosarcoma (HP:0002859) | 1.66185162 |
114 | Gastrointestinal inflammation (HP:0004386) | 1.65909626 |
115 | Metaphyseal cupping (HP:0003021) | 1.65652158 |
116 | Premature graying of hair (HP:0002216) | 1.65611582 |
117 | Abnormal tarsal ossification (HP:0008369) | 1.65083286 |
118 | Birth length less than 3rd percentile (HP:0003561) | 1.64898522 |
119 | Diastasis recti (HP:0001540) | 1.64812026 |
120 | Hyperglycinemia (HP:0002154) | 1.64377893 |
121 | Cellulitis (HP:0100658) | 1.64137063 |
122 | Increased muscle lipid content (HP:0009058) | 1.63353707 |
123 | Progressive muscle weakness (HP:0003323) | 1.62746288 |
124 | Abnormality of the calcaneus (HP:0008364) | 1.62385711 |
125 | Blepharitis (HP:0000498) | 1.61798894 |
126 | Acute lymphatic leukemia (HP:0006721) | 1.60926141 |
127 | Sparse eyelashes (HP:0000653) | 1.60759121 |
128 | Calcaneovalgus deformity (HP:0001848) | 1.60552405 |
129 | Papilloma (HP:0012740) | 1.60255473 |
130 | Verrucae (HP:0200043) | 1.60255473 |
131 | Hyperacusis (HP:0010780) | 1.60241388 |
132 | Hyperthyroidism (HP:0000836) | 1.60045190 |
133 | Agammaglobulinemia (HP:0004432) | 1.59928330 |
134 | Petechiae (HP:0000967) | 1.59587487 |
135 | Milia (HP:0001056) | 1.59311067 |
136 | Renal Fanconi syndrome (HP:0001994) | 1.59153608 |
137 | Cellular immunodeficiency (HP:0005374) | 1.58400706 |
138 | Ridged nail (HP:0001807) | 1.58304569 |
139 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.58050175 |
140 | Abnormality of midbrain morphology (HP:0002418) | 1.57728482 |
141 | Molar tooth sign on MRI (HP:0002419) | 1.57728482 |
142 | Concave nail (HP:0001598) | 1.56911696 |
143 | Agnosia (HP:0010524) | 1.56709324 |
144 | Inflammation of the large intestine (HP:0002037) | 1.56545222 |
145 | Deep philtrum (HP:0002002) | 1.56111739 |
146 | Esophageal atresia (HP:0002032) | 1.55832498 |
147 | Aplasia cutis congenita (HP:0001057) | 1.55689135 |
148 | Partial duplication of the phalanx of hand (HP:0009999) | 1.55579581 |
149 | Premature ovarian failure (HP:0008209) | 1.55034065 |
150 | IgG deficiency (HP:0004315) | 1.53575509 |
151 | Entropion (HP:0000621) | 1.53478778 |
152 | Neoplasm of the colon (HP:0100273) | 1.53144627 |
153 | Lymphopenia (HP:0001888) | 1.52827444 |
154 | Horseshoe kidney (HP:0000085) | 1.52701365 |
155 | Respiratory difficulties (HP:0002880) | 1.51902619 |
156 | * Short nose (HP:0003196) | 1.51291532 |
157 | Carpal bone hypoplasia (HP:0001498) | 1.51187522 |
158 | Increased density of long bones (HP:0006392) | 1.51157362 |
159 | Insomnia (HP:0100785) | 1.50231086 |
160 | Forearm undergrowth (HP:0009821) | 1.49782822 |
161 | Abnormality of the nasolacrimal system (HP:0000614) | 1.48501577 |
162 | Truncus arteriosus (HP:0001660) | 1.47288843 |
163 | Hepatic necrosis (HP:0002605) | 1.46914380 |
164 | Patellar dislocation (HP:0002999) | 1.46677714 |
165 | Intestinal fistula (HP:0100819) | 1.46274583 |
166 | Progressive external ophthalmoplegia (HP:0000590) | 1.45905067 |
167 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.45190445 |
168 | Vaginal fistula (HP:0004320) | 1.45167079 |
169 | Anophthalmia (HP:0000528) | 1.41007006 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NME2 | 4.32056744 |
2 | EEF2K | 3.27046591 |
3 | TLK1 | 3.16588552 |
4 | RPS6KB2 | 2.86090586 |
5 | LRRK2 | 2.85217960 |
6 | WEE1 | 2.71387726 |
7 | VRK2 | 2.42154528 |
8 | MAP4K1 | 2.37931751 |
9 | CDC7 | 2.35946209 |
10 | BUB1 | 2.15930224 |
11 | TGFBR1 | 2.11957892 |
12 | PASK | 2.07971409 |
13 | NEK2 | 1.95265894 |
14 | MST4 | 1.91956927 |
15 | ICK | 1.90451798 |
16 | SMG1 | 1.88017862 |
17 | MAP3K10 | 1.83642108 |
18 | DYRK3 | 1.82915907 |
19 | SRPK1 | 1.82786122 |
20 | PKN2 | 1.79645580 |
21 | RPS6KA4 | 1.78271607 |
22 | STK10 | 1.77014990 |
23 | TYRO3 | 1.75951195 |
24 | EPHB2 | 1.72181793 |
25 | EIF2AK1 | 1.66038836 |
26 | VRK1 | 1.57648914 |
27 | WNK4 | 1.56038820 |
28 | AURKB | 1.50708158 |
29 | PNCK | 1.45150390 |
30 | FLT3 | 1.43665200 |
31 | MAPKAPK3 | 1.40248533 |
32 | CDK7 | 1.39154875 |
33 | PLK4 | 1.37743654 |
34 | PIM2 | 1.34914623 |
35 | NEK1 | 1.33721232 |
36 | MKNK1 | 1.33220907 |
37 | CDK12 | 1.30705804 |
38 | ZAK | 1.29941888 |
39 | ACVR1B | 1.29715205 |
40 | BTK | 1.24237856 |
41 | CDK4 | 1.23377653 |
42 | CDK8 | 1.21684926 |
43 | GRK6 | 1.18595883 |
44 | PIM1 | 1.18139601 |
45 | ILK | 1.16131855 |
46 | TAF1 | 1.13810809 |
47 | TEC | 1.13647137 |
48 | MAP3K8 | 1.12825698 |
49 | TSSK6 | 1.11757009 |
50 | BRSK2 | 1.09789366 |
51 | SCYL2 | 1.08285923 |
52 | TYK2 | 1.07572410 |
53 | BRAF | 1.04523220 |
54 | TESK2 | 1.03488583 |
55 | TTK | 1.01291322 |
56 | STK16 | 0.99673411 |
57 | NLK | 0.99559530 |
58 | CDK6 | 0.99223466 |
59 | PLK1 | 0.98018885 |
60 | ATR | 0.97899646 |
61 | LATS2 | 0.97556422 |
62 | EIF2AK3 | 0.95828148 |
63 | KDR | 0.92065474 |
64 | BLK | 0.91103883 |
65 | CDK19 | 0.90970817 |
66 | ZAP70 | 0.89175845 |
67 | PAK4 | 0.87170394 |
68 | CSNK1E | 0.85123185 |
69 | BRSK1 | 0.84339486 |
70 | EPHA2 | 0.82249587 |
71 | MAP3K3 | 0.82114313 |
72 | DMPK | 0.80969448 |
73 | STK4 | 0.80602489 |
74 | MKNK2 | 0.77285466 |
75 | WNK1 | 0.76874216 |
76 | ITK | 0.76489732 |
77 | MST1R | 0.75968227 |
78 | KIT | 0.75918076 |
79 | CHEK1 | 0.75351816 |
80 | CSNK2A2 | 0.74499243 |
81 | RPS6KA5 | 0.74477420 |
82 | LATS1 | 0.74233862 |
83 | IKBKB | 0.71920013 |
84 | STK3 | 0.70885180 |
85 | JAK3 | 0.70140728 |
86 | MTOR | 0.69070952 |
87 | IRAK3 | 0.68637113 |
88 | DYRK2 | 0.68002477 |
89 | CDK1 | 0.67195495 |
90 | PAK2 | 0.65913108 |
91 | CLK1 | 0.65792069 |
92 | RPS6KL1 | 0.65480326 |
93 | STK24 | 0.65473095 |
94 | MAP2K3 | 0.65023599 |
95 | AURKA | 0.64572994 |
96 | ALK | 0.63165573 |
97 | CSF1R | 0.62811351 |
98 | MAPK15 | 0.62748794 |
99 | DYRK1B | 0.61903949 |
100 | LCK | 0.61481778 |
101 | RPS6KA6 | 0.61276599 |
102 | TRIB3 | 0.58819740 |
103 | NME1 | 0.57773627 |
104 | SYK | 0.56998511 |
105 | TGFBR2 | 0.56747915 |
106 | PDK2 | 0.56379424 |
107 | CHEK2 | 0.56199732 |
108 | CDK3 | 0.56015824 |
109 | MAP2K2 | 0.55556457 |
110 | CDK9 | 0.55534397 |
111 | ATM | 0.53811766 |
112 | CDK2 | 0.52750495 |
113 | CSNK2A1 | 0.51011496 |
114 | CDK11A | 0.48375529 |
115 | DAPK3 | 0.47977114 |
116 | IKBKE | 0.45595249 |
117 | ABL2 | 0.43465108 |
118 | TBK1 | 0.42511169 |
119 | PRPF4B | 0.42204610 |
120 | BRD4 | 0.41876484 |
121 | AKT1 | 0.41202702 |
122 | LYN | 0.40429336 |
123 | TXK | 0.39704415 |
124 | MELK | 0.39652736 |
125 | MAP3K11 | 0.39153946 |
126 | MAPK14 | 0.39051506 |
127 | PRKDC | 0.38267388 |
128 | PTK6 | 0.37703415 |
129 | PAK1 | 0.36517342 |
130 | RPS6KA1 | 0.35721651 |
131 | IRAK2 | 0.35421767 |
132 | HCK | 0.34751181 |
133 | PLK3 | 0.34639390 |
134 | MAPKAPK2 | 0.34631353 |
135 | CCNB1 | 0.33600593 |
136 | PBK | 0.33572751 |
137 | TRPM7 | 0.33005543 |
138 | TTN | 0.32093189 |
139 | RPS6KC1 | 0.31549212 |
140 | AKT2 | 0.30078414 |
141 | PRKCI | 0.28555262 |
142 | KSR1 | 0.28487314 |
143 | MARK2 | 0.27737114 |
144 | MAPKAPK5 | 0.27657762 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Ribosome_Homo sapiens_hsa03010 | 7.85015802 |
2 | DNA replication_Homo sapiens_hsa03030 | 3.70996955 |
3 | Spliceosome_Homo sapiens_hsa03040 | 3.11495659 |
4 | Mismatch repair_Homo sapiens_hsa03430 | 3.10442223 |
5 | RNA polymerase_Homo sapiens_hsa03020 | 2.60748784 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.58123624 |
7 | Homologous recombination_Homo sapiens_hsa03440 | 2.30722825 |
8 | RNA transport_Homo sapiens_hsa03013 | 2.28178488 |
9 | Proteasome_Homo sapiens_hsa03050 | 2.15652181 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.14177949 |
11 | Base excision repair_Homo sapiens_hsa03410 | 2.09493890 |
12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.87320427 |
13 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.77814356 |
14 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.76858234 |
15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.75547854 |
16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.70982654 |
17 | Cell cycle_Homo sapiens_hsa04110 | 1.70090509 |
18 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.54844828 |
19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.50251431 |
20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.49671898 |
21 | RNA degradation_Homo sapiens_hsa03018 | 1.45963200 |
22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.45525682 |
23 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.42755046 |
24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.29563615 |
25 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.29248737 |
26 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.18022819 |
27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16036374 |
28 | Protein export_Homo sapiens_hsa03060 | 1.11434471 |
29 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.11242518 |
30 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.09530528 |
31 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.02747508 |
32 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01973485 |
33 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.97961417 |
34 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.96277804 |
35 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.94982178 |
36 | HTLV-I infection_Homo sapiens_hsa05166 | 0.91620143 |
37 | Thyroid cancer_Homo sapiens_hsa05216 | 0.88946812 |
38 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.84011976 |
39 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.80599607 |
40 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.80271826 |
41 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.78587998 |
42 | Measles_Homo sapiens_hsa05162 | 0.78117812 |
43 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77414286 |
44 | Purine metabolism_Homo sapiens_hsa00230 | 0.74316108 |
45 | Sulfur relay system_Homo sapiens_hsa04122 | 0.71936939 |
46 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.71686448 |
47 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.71680037 |
48 | Parkinsons disease_Homo sapiens_hsa05012 | 0.71548925 |
49 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.70888686 |
50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.70498053 |
51 | Huntingtons disease_Homo sapiens_hsa05016 | 0.68655322 |
52 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.68281746 |
53 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.67704173 |
54 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.67415507 |
55 | Carbon metabolism_Homo sapiens_hsa01200 | 0.67195031 |
56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.67050631 |
57 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.66997677 |
58 | Apoptosis_Homo sapiens_hsa04210 | 0.65669428 |
59 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65387407 |
60 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.64430685 |
61 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.61900243 |
62 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.61335025 |
63 | Hepatitis B_Homo sapiens_hsa05161 | 0.61284637 |
64 | Legionellosis_Homo sapiens_hsa05134 | 0.60496453 |
65 | Alcoholism_Homo sapiens_hsa05034 | 0.58447329 |
66 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.56807125 |
67 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.56653244 |
68 | Leishmaniasis_Homo sapiens_hsa05140 | 0.55562510 |
69 | Colorectal cancer_Homo sapiens_hsa05210 | 0.55437080 |
70 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.55048232 |
71 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.53462152 |
72 | Bladder cancer_Homo sapiens_hsa05219 | 0.52415607 |
73 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.50321056 |
74 | Viral myocarditis_Homo sapiens_hsa05416 | 0.49775356 |
75 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.49215751 |
76 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.48690110 |
77 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.48631113 |
78 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.47959118 |
79 | Shigellosis_Homo sapiens_hsa05131 | 0.47674954 |
80 | Pathways in cancer_Homo sapiens_hsa05200 | 0.47392217 |
81 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.45509498 |
82 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.45457872 |
83 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.43640905 |
84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.43107988 |
85 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.42829493 |
86 | Influenza A_Homo sapiens_hsa05164 | 0.42553463 |
87 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.41819360 |
88 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.41167346 |
89 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.40331752 |
90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39908962 |
91 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.39870537 |
92 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39746799 |
93 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.39619957 |
94 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.38248312 |
95 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.38031320 |
96 | Adherens junction_Homo sapiens_hsa04520 | 0.37308904 |
97 | Platelet activation_Homo sapiens_hsa04611 | 0.36803990 |
98 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.36785241 |
99 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.36184358 |
100 | Asthma_Homo sapiens_hsa05310 | 0.34434902 |
101 | Allograft rejection_Homo sapiens_hsa05330 | 0.34297937 |
102 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.33637108 |
103 | Alzheimers disease_Homo sapiens_hsa05010 | 0.33535129 |
104 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.33312967 |
105 | Prostate cancer_Homo sapiens_hsa05215 | 0.33239211 |
106 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.33049042 |
107 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.32948005 |
108 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.30582050 |
109 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.29064992 |
110 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.28904668 |
111 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.28838427 |
112 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.28202913 |
113 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.28122752 |
114 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.27518030 |
115 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.23736332 |
116 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.23388409 |
117 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.23190252 |
118 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.22162264 |
119 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.18965217 |
120 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.18242489 |
121 | Melanoma_Homo sapiens_hsa05218 | 0.17750880 |
122 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.17314997 |
123 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.17100054 |
124 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.14060015 |
125 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.13056853 |
126 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.12340880 |
127 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.11215092 |
128 | Galactose metabolism_Homo sapiens_hsa00052 | 0.10536711 |
129 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.09303436 |
130 | Melanogenesis_Homo sapiens_hsa04916 | 0.09026616 |
131 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.07761345 |
132 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.06182817 |
133 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.06097111 |
134 | Endometrial cancer_Homo sapiens_hsa05213 | 0.05656889 |
135 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.04874993 |