RPS24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S24E family of ribosomal proteins. It is located in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* translational termination (GO:0006415)9.98828042
2ribosomal small subunit assembly (GO:0000028)9.49926598
3* translational elongation (GO:0006414)8.43875169
4* ribosomal small subunit biogenesis (GO:0042274)8.39925517
5* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)8.31713483
6* protein targeting to ER (GO:0045047)8.15399520
7* cotranslational protein targeting to membrane (GO:0006613)8.14621221
8* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)7.87926497
9* establishment of protein localization to endoplasmic reticulum (GO:0072599)7.81512431
10* cellular protein complex disassembly (GO:0043624)7.69414353
11* viral life cycle (GO:0019058)7.68848221
12* protein localization to endoplasmic reticulum (GO:0070972)7.58407955
13* translational initiation (GO:0006413)7.26963840
14ribosomal large subunit biogenesis (GO:0042273)6.84038440
15* protein complex disassembly (GO:0043241)6.77609345
16* maturation of SSU-rRNA (GO:0030490)6.55158921
17* macromolecular complex disassembly (GO:0032984)6.30860900
18* nuclear-transcribed mRNA catabolic process (GO:0000956)5.58459682
19* protein targeting to membrane (GO:0006612)5.46106532
20* mRNA catabolic process (GO:0006402)5.30643332
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.13423177
22* RNA catabolic process (GO:0006401)4.95243713
23ATP synthesis coupled proton transport (GO:0015986)4.81113199
24energy coupled proton transport, down electrochemical gradient (GO:0015985)4.81113199
25* translation (GO:0006412)4.73885634
26* ribonucleoprotein complex biogenesis (GO:0022613)4.62524606
27formation of translation preinitiation complex (GO:0001731)4.02884242
28* rRNA processing (GO:0006364)3.69232360
29regulation of translational fidelity (GO:0006450)3.63652990
30* establishment of protein localization to membrane (GO:0090150)3.62717745
31* rRNA metabolic process (GO:0016072)3.58115069
32ncRNA 3-end processing (GO:0043628)3.52836874
33DNA unwinding involved in DNA replication (GO:0006268)3.45486624
34negative regulation of RNA splicing (GO:0033119)3.32900872
35DNA strand elongation involved in DNA replication (GO:0006271)3.29615255
36* establishment of protein localization to organelle (GO:0072594)3.29526674
37oxidative phosphorylation (GO:0006119)3.24116697
38* protein targeting (GO:0006605)3.21558679
39* cellular component biogenesis (GO:0044085)3.17945123
40establishment of protein localization to mitochondrial membrane (GO:0090151)3.17790267
41telomere maintenance via semi-conservative replication (GO:0032201)3.16958416
42DNA strand elongation (GO:0022616)3.10440210
43respiratory electron transport chain (GO:0022904)3.09490179
44electron transport chain (GO:0022900)3.02521454
45DNA deamination (GO:0045006)2.95600114
46heterochromatin organization (GO:0070828)2.90524457
47* cellular component disassembly (GO:0022411)2.87393747
48DNA replication initiation (GO:0006270)2.84484507
49viral protein processing (GO:0019082)2.80092140
50protein localization to kinetochore (GO:0034501)2.79039068
51telomere maintenance via recombination (GO:0000722)2.75306141
52mitotic recombination (GO:0006312)2.74784902
53spliceosomal complex assembly (GO:0000245)2.74141917
54* protein localization to membrane (GO:0072657)2.73717145
55spliceosomal snRNP assembly (GO:0000387)2.72504360
56histone H2B ubiquitination (GO:0033523)2.66738354
57folic acid-containing compound biosynthetic process (GO:0009396)2.64523667
58chaperone-mediated protein transport (GO:0072321)2.64020044
59* gene expression (GO:0010467)2.60220098
60mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.58433264
61negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.57740615
62establishment of integrated proviral latency (GO:0075713)2.57107457
63ATP biosynthetic process (GO:0006754)2.53992984
64kinetochore organization (GO:0051383)2.53766096
65protein localization to chromosome, centromeric region (GO:0071459)2.53591152
66chromatin remodeling at centromere (GO:0031055)2.53122454
67inner mitochondrial membrane organization (GO:0007007)2.52714251
68telomere maintenance via telomere lengthening (GO:0010833)2.51689497
69mitotic nuclear envelope disassembly (GO:0007077)2.51659293
70RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.51426195
71mRNA splicing, via spliceosome (GO:0000398)2.51426195
72regulation of protein heterodimerization activity (GO:0043497)2.51082227
73nucleotide-excision repair, DNA gap filling (GO:0006297)2.50345399
74ribosome biogenesis (GO:0042254)2.50142507
75RNA splicing, via transesterification reactions (GO:0000375)2.49612625
76antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.49239165
77antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.49239165
78ribosome assembly (GO:0042255)2.48534497
79regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.47755723
80* protein localization to organelle (GO:0033365)2.47185769
81CENP-A containing nucleosome assembly (GO:0034080)2.46686673
82regulation of histone H3-K9 methylation (GO:0051570)2.46043423
83ribonucleoprotein complex assembly (GO:0022618)2.45420846
84DNA replication-dependent nucleosome organization (GO:0034723)2.44959568
85DNA replication-dependent nucleosome assembly (GO:0006335)2.44959568
86termination of RNA polymerase II transcription (GO:0006369)2.44819389
87* ncRNA processing (GO:0034470)2.40422472
88DNA replication-independent nucleosome assembly (GO:0006336)2.40421010
89DNA replication-independent nucleosome organization (GO:0034724)2.40421010
90nuclear pore organization (GO:0006999)2.36248508
91pseudouridine synthesis (GO:0001522)2.35887638
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.35695482
93histone mRNA metabolic process (GO:0008334)2.35170818
94negative regulation of mRNA processing (GO:0050686)2.34012958
95membrane disassembly (GO:0030397)2.32433658
96nuclear envelope disassembly (GO:0051081)2.32433658
97purine nucleoside triphosphate biosynthetic process (GO:0009145)2.32303917
98nuclear pore complex assembly (GO:0051292)2.31822676
99DNA replication checkpoint (GO:0000076)2.31683795
100interferon-gamma secretion (GO:0072643)2.31575280
101regulation of RNA export from nucleus (GO:0046831)2.30939333
102ribonucleoprotein complex subunit organization (GO:0071826)2.30892459
103aerobic respiration (GO:0009060)2.30828257
104* single-organism cellular localization (GO:1902580)2.28169703
105mitotic chromosome condensation (GO:0007076)2.27949964
106alternative mRNA splicing, via spliceosome (GO:0000380)2.27440469
107ribonucleoside triphosphate biosynthetic process (GO:0009201)2.27378462
108pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.25565503
109regulation of mitochondrial translation (GO:0070129)2.24400947
110chromosome condensation (GO:0030261)2.24385996
111pore complex assembly (GO:0046931)2.24237426
112mitotic sister chromatid segregation (GO:0000070)2.23991973
113sister chromatid segregation (GO:0000819)2.23337388
114chaperone-mediated protein complex assembly (GO:0051131)2.22602171
115DNA duplex unwinding (GO:0032508)2.22578222
116exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.19998951
117DNA geometric change (GO:0032392)2.19970912
118DNA topological change (GO:0006265)2.19137147
119* ncRNA metabolic process (GO:0034660)2.18807088
120negative regulation of translational initiation (GO:0045947)2.18600473
121substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.17600204
122substrate-independent telencephalic tangential migration (GO:0021826)2.17600204
123chromatin assembly (GO:0031497)2.16525979
124chromatin assembly or disassembly (GO:0006333)2.16127498
125antigen processing and presentation of endogenous antigen (GO:0019883)2.15756062
126negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.15027447
127regulation of translational initiation (GO:0006446)2.14398715
128DNA-templated transcription, termination (GO:0006353)2.12969693
129nucleobase biosynthetic process (GO:0046112)2.12324716
130kinetochore assembly (GO:0051382)2.11629125
131negative regulation of mRNA metabolic process (GO:1903312)2.11547267
132mitotic metaphase plate congression (GO:0007080)2.11416069
133transcription-coupled nucleotide-excision repair (GO:0006283)2.11386822
134* viral transcription (GO:0019083)10.4051609

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.92422335
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.60170466
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.74379852
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.70259586
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.52772549
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.37462604
7TP63_17297297_ChIP-ChIP_HaCaT_Human3.34655314
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.09677530
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.76241677
10FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.73121612
11* XRN2_22483619_ChIP-Seq_HELA_Human2.64472008
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.61349743
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.59323907
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.56503423
15* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.54435303
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.24661216
17MYC_22102868_ChIP-Seq_BL_Human2.21489631
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.18759888
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.18452095
20VDR_23849224_ChIP-Seq_CD4+_Human2.14291869
21HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.13991238
22* TTF2_22483619_ChIP-Seq_HELA_Human2.12704913
23FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.10838306
24TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.09058008
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.08903107
26KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.07788586
27ELF1_17652178_ChIP-ChIP_JURKAT_Human2.06388328
28* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.05145728
29TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.02444937
30RBPJ_22232070_ChIP-Seq_NCS_Mouse1.99060422
31FOXP3_21729870_ChIP-Seq_TREG_Human1.86774755
32JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.85057499
33* ELK1_19687146_ChIP-ChIP_HELA_Human1.83459521
34* DCP1A_22483619_ChIP-Seq_HELA_Human1.78743805
35VDR_21846776_ChIP-Seq_THP-1_Human1.75396398
36* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.69027376
37* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.68448708
38* E2F1_21310950_ChIP-Seq_MCF-7_Human1.57938193
39CIITA_25753668_ChIP-Seq_RAJI_Human1.55425951
40AR_21909140_ChIP-Seq_LNCAP_Human1.52735438
41SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.51633952
42CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.44750879
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.43785240
44* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.40866785
45FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.39611307
46GABP_19822575_ChIP-Seq_HepG2_Human1.39163840
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38605578
48* ERG_20887958_ChIP-Seq_HPC-7_Mouse1.36952907
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.36623351
50MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.36497375
51TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.36412263
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.35683539
53KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.35464280
54SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.32325033
55MYCN_18555785_ChIP-Seq_MESCs_Mouse1.31411515
56ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.30105998
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.30007113
58FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.26502560
59KDM5A_27292631_Chip-Seq_BREAST_Human1.25343682
60MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.24907966
61NANOG_18555785_ChIP-Seq_MESCs_Mouse1.24747070
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.24257771
63IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.23692560
64ESR1_15608294_ChIP-ChIP_MCF-7_Human1.22828899
65SPI1_23547873_ChIP-Seq_NB4_Human1.22639452
66STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18236755
67UTX_26944678_Chip-Seq_JUKART_Human1.18013109
68CTCF_18555785_ChIP-Seq_MESCs_Mouse1.17190492
69MAF_26560356_Chip-Seq_TH1_Human1.15193211
70E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14282090
71SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.13093310
72KLF4_18555785_ChIP-Seq_MESCs_Mouse1.12776547
73TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.11678824
74THAP11_20581084_ChIP-Seq_MESCs_Mouse1.09824863
75FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.07910364
76CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.07680457
77CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.07533844
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07201927
79KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.07199574
80OCT4_18692474_ChIP-Seq_MEFs_Mouse1.06898684
81MYB_26560356_Chip-Seq_TH2_Human1.05308810
82YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.05250238
83TP63_19390658_ChIP-ChIP_HaCaT_Human1.04953793
84SOX2_18692474_ChIP-Seq_MEFs_Mouse1.03742896
85* MYC_18940864_ChIP-ChIP_HL60_Human1.03027502
86MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.02897340
87CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.02393848
88NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.01984904
89* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.01391319
90MAF_26560356_Chip-Seq_TH2_Human1.00266454
91STAT4_19710469_ChIP-ChIP_TH1__Mouse1.00216906
92* ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.99442738
93PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.99381578
94* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.98736539
95NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.98453708
96SCL_19346495_ChIP-Seq_HPC-7_Human0.98341746
97E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.97910717
98* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.96330093
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.95769508
100POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.95628918
101KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.95521278
102ZNF263_19887448_ChIP-Seq_K562_Human0.95498573
103* CHD1_26751641_Chip-Seq_LNCaP_Human0.95294099
104BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95259104
105MYB_26560356_Chip-Seq_TH1_Human0.94960969
106SOX2_16153702_ChIP-ChIP_HESCs_Human0.94363479
107TCF3_18692474_ChIP-Seq_MEFs_Mouse0.94167420
108YY1_21170310_ChIP-Seq_MESCs_Mouse0.94055063
109TCF7_22412390_ChIP-Seq_EML_Mouse0.93941220
110VDR_24763502_ChIP-Seq_THP-1_Human0.93240736
111SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.92644837
112HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.92299225
113GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.91688590
114TFEB_21752829_ChIP-Seq_HELA_Human0.91200088
115MYB_21317192_ChIP-Seq_ERMYB_Mouse0.90814559
116SOX2_18555785_ChIP-Seq_MESCs_Mouse0.90589744
117NANOG_21062744_ChIP-ChIP_HESCs_Human0.90502448
118PADI4_21655091_ChIP-ChIP_MCF-7_Human0.90304597
119POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.90166363
120TET1_21451524_ChIP-Seq_MESCs_Mouse0.89936358
121FOXP1_21924763_ChIP-Seq_HESCs_Human0.88289324
122CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.85846353
123KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.85036790
124KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.85036790
125KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.85036790
126* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.83352014
127SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.81637748
128SRF_21415370_ChIP-Seq_HL-1_Mouse0.81292895
129PPARG_19300518_ChIP-PET_3T3-L1_Mouse0.80243522
130NCOR1_26117541_ChIP-Seq_K562_Human0.79192120

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.37236602
2MP0006292_abnormal_olfactory_placode4.31378112
3MP0003693_abnormal_embryo_hatching3.80769908
4MP0004957_abnormal_blastocyst_morpholog3.35487864
5MP0000566_synostosis3.08331102
6MP0010094_abnormal_chromosome_stability2.71945428
7MP0003077_abnormal_cell_cycle2.58833089
8MP0003111_abnormal_nucleus_morphology2.45019795
9MP0010352_gastrointestinal_tract_polyps2.41138020
10MP0002396_abnormal_hematopoietic_system2.38053545
11MP0003763_abnormal_thymus_physiology2.16875241
12MP0000490_abnormal_crypts_of1.99829848
13MP0008057_abnormal_DNA_replication1.97945055
14MP0008007_abnormal_cellular_replicative1.91933425
15MP0002166_altered_tumor_susceptibility1.86059963
16MP0004808_abnormal_hematopoietic_stem1.69939194
17MP0002938_white_spotting1.67959652
18MP0002697_abnormal_eye_size1.66151100
19MP0008932_abnormal_embryonic_tissue1.64619788
20MP0009333_abnormal_splenocyte_physiolog1.63749572
21MP0000350_abnormal_cell_proliferation1.58251042
22MP0001286_abnormal_eye_development1.57263435
23MP0008058_abnormal_DNA_repair1.56965700
24MP0008789_abnormal_olfactory_epithelium1.52904245
25MP0004381_abnormal_hair_follicle1.51804887
26MP0003567_abnormal_fetal_cardiomyocyte1.51465101
27MP0000685_abnormal_immune_system1.50555231
28MP0002006_tumorigenesis1.50034149
29MP0002398_abnormal_bone_marrow1.49617253
30MP0002234_abnormal_pharynx_morphology1.48869055
31MP0002796_impaired_skin_barrier1.48408570
32MP0000703_abnormal_thymus_morphology1.48130613
33MP0003890_abnormal_embryonic-extraembry1.47305911
34MP0003941_abnormal_skin_development1.46851539
35MP0001800_abnormal_humoral_immune1.46116733
36MP0001730_embryonic_growth_arrest1.45057440
37MP0003786_premature_aging1.43381667
38MP0006054_spinal_hemorrhage1.42334450
39MP0004185_abnormal_adipocyte_glucose1.41429684
40MP0000049_abnormal_middle_ear1.40515165
41MP0003937_abnormal_limbs/digits/tail_de1.38116390
42MP0001835_abnormal_antigen_presentation1.36344099
43MP0002722_abnormal_immune_system1.35323333
44MP0005501_abnormal_skin_physiology1.34358913
45MP0000762_abnormal_tongue_morphology1.34031561
46MP0002653_abnormal_ependyma_morphology1.33979934
47MP0002009_preneoplasia1.33205900
48MP0005394_taste/olfaction_phenotype1.33146844
49MP0005499_abnormal_olfactory_system1.33146844
50MP0002249_abnormal_larynx_morphology1.33143099
51MP0002092_abnormal_eye_morphology1.32873689
52MP0003123_paternal_imprinting1.31137416
53MP0005174_abnormal_tail_pigmentation1.29970200
54MP0010234_abnormal_vibrissa_follicle1.28872983
55MP0002019_abnormal_tumor_incidence1.27720488
56MP0001873_stomach_inflammation1.27218210
57MP0010155_abnormal_intestine_physiology1.27030098
58MP0000465_gastrointestinal_hemorrhage1.25685929
59MP0005397_hematopoietic_system_phenotyp1.24290389
60MP0001545_abnormal_hematopoietic_system1.24290389
61MP0002420_abnormal_adaptive_immunity1.20604336
62MP0003942_abnormal_urinary_system1.20485369
63MP0000537_abnormal_urethra_morphology1.19945453
64MP0003300_gastrointestinal_ulcer1.19671339
65MP0003186_abnormal_redox_activity1.19617262
66MP0000689_abnormal_spleen_morphology1.18692590
67MP0002452_abnormal_antigen_presenting1.18292255
68MP0001819_abnormal_immune_cell1.17368938
69MP0010307_abnormal_tumor_latency1.16990857
70MP0005076_abnormal_cell_differentiation1.16922355
71MP0000428_abnormal_craniofacial_morphol1.16805274
72MP0005671_abnormal_response_to1.15606309
73MP0000858_altered_metastatic_potential1.15407086
74MP0001216_abnormal_epidermal_layer1.15249018
75MP0000716_abnormal_immune_system1.15107247
76MP0002429_abnormal_blood_cell1.14275395
77MP0001697_abnormal_embryo_size1.13963361
78MP0001346_abnormal_lacrimal_gland1.13927360
79MP0003122_maternal_imprinting1.13200710
80MP0002163_abnormal_gland_morphology1.13198414
81MP0002160_abnormal_reproductive_system1.12546713
82MP0003938_abnormal_ear_development1.11468959
83MP0002060_abnormal_skin_morphology1.11354897
84MP0002405_respiratory_system_inflammati1.09707422
85MP0002080_prenatal_lethality1.09567396
86MP0003121_genomic_imprinting1.09052327
87MP0003315_abnormal_perineum_morphology1.08888291
88MP0002233_abnormal_nose_morphology1.08219493
89MP0000313_abnormal_cell_death1.06997814
90MP0002210_abnormal_sex_determination1.06738840
91MP0001853_heart_inflammation1.05631724
92MP0000383_abnormal_hair_follicle1.05485857
93MP0003453_abnormal_keratinocyte_physiol1.05381681
94MP0002723_abnormal_immune_serum1.05308791
95MP0002084_abnormal_developmental_patter1.05244838
96MP0002095_abnormal_skin_pigmentation1.05208502
97MP0002086_abnormal_extraembryonic_tissu1.04198824
98MP0005023_abnormal_wound_healing1.03376086
99MP0004197_abnormal_fetal_growth/weight/1.02998557
100MP0001672_abnormal_embryogenesis/_devel1.02892440
101MP0005380_embryogenesis_phenotype1.02892440
102MP0003436_decreased_susceptibility_to1.02291604
103MP0002085_abnormal_embryonic_tissue1.02086925
104MP0005000_abnormal_immune_tolerance1.02074467
105MP0002111_abnormal_tail_morphology1.01799808
106MP0003566_abnormal_cell_adhesion1.01445004
107MP0004947_skin_inflammation0.97696360
108MP0003861_abnormal_nervous_system0.97525664
109MP0003866_abnormal_defecation0.97476599
110MP0000631_abnormal_neuroendocrine_gland0.96530800
111MP0002098_abnormal_vibrissa_morphology0.96389215
112MP0003755_abnormal_palate_morphology0.96279010
113MP0001485_abnormal_pinna_reflex0.95767082
114MP0000377_abnormal_hair_follicle0.95188049
115MP0003718_maternal_effect0.94924893
116MP0002088_abnormal_embryonic_growth/wei0.94790492
117MP0005025_abnormal_response_to0.93868846
118MP0003984_embryonic_growth_retardation0.93766129
119MP0002132_abnormal_respiratory_system0.93112805
120MP0009278_abnormal_bone_marrow0.93013088
121MP0000477_abnormal_intestine_morphology0.91466497
122MP0005387_immune_system_phenotype0.89246923
123MP0001790_abnormal_immune_system0.89246923
124MP0003136_yellow_coat_color0.87827222
125MP0009053_abnormal_anal_canal0.87396788
126MP0010030_abnormal_orbit_morphology0.85617090
127MP0002116_abnormal_craniofacial_bone0.84063789
128MP0000778_abnormal_nervous_system0.82913716
129MP0004142_abnormal_muscle_tone0.81774442
130MP0010678_abnormal_skin_adnexa0.81399013
131MP0000534_abnormal_ureter_morphology0.79153450
132MP0001727_abnormal_embryo_implantation0.78970577
133MP0003935_abnormal_craniofacial_develop0.78371197
134MP0005408_hypopigmentation0.78337212
135MP0001145_abnormal_male_reproductive0.78227122
136MP0009931_abnormal_skin_appearance0.78019282
137MP0009785_altered_susceptibility_to0.77660153
138MP0003303_peritoneal_inflammation0.77514659
139MP0003787_abnormal_imprinting0.77206220
140MP0008995_early_reproductive_senescence0.77060217
141MP0001293_anophthalmia0.77049835
142MP0009672_abnormal_birth_weight0.76755589
143MP0009250_abnormal_appendicular_skeleto0.76659922
144MP0001529_abnormal_vocalization0.76255280
145MP0003448_altered_tumor_morphology0.74586447
146MP0005075_abnormal_melanosome_morpholog0.73750669
147MP0004742_abnormal_vestibular_system0.70717864
148MP0000678_abnormal_parathyroid_gland0.69383052
149MP0005391_vision/eye_phenotype0.69244750
150MP0001929_abnormal_gametogenesis0.68954574
151MP0002932_abnormal_joint_morphology0.67873012
152MP0005389_reproductive_system_phenotype0.67788360
153MP0000026_abnormal_inner_ear0.66822475
154MP0003385_abnormal_body_wall0.66486327
155MP0002114_abnormal_axial_skeleton0.65305378
156MP0001340_abnormal_eyelid_morphology0.64216756
157MP0000432_abnormal_head_morphology0.62570503
158MP0000653_abnormal_sex_gland0.61190335
159MP0000955_abnormal_spinal_cord0.60792193
160MP0001881_abnormal_mammary_gland0.60250332
161MP0005195_abnormal_posterior_eye0.60127049

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)9.38545887
2Abnormal number of erythroid precursors (HP:0012131)8.18828359
3* Reticulocytopenia (HP:0001896)6.82744457
4* Macrocytic anemia (HP:0001972)5.86564459
5* Pallor (HP:0000980)5.47650838
6Partial duplication of thumb phalanx (HP:0009944)4.65723701
7Thrombocytosis (HP:0001894)4.15190295
8Colon cancer (HP:0003003)3.83380201
9Duplication of thumb phalanx (HP:0009942)3.38635842
10Acute necrotizing encephalopathy (HP:0006965)3.04926312
11Aplasia/Hypoplasia of the sacrum (HP:0008517)3.03649781
1211 pairs of ribs (HP:0000878)3.00050994
13Septo-optic dysplasia (HP:0100842)2.98788917
14Abnormality of the parietal bone (HP:0002696)2.90550981
15Acute encephalopathy (HP:0006846)2.89369519
16Abnormal mitochondria in muscle tissue (HP:0008316)2.87580087
17Aplastic anemia (HP:0001915)2.87194144
18Absent thumb (HP:0009777)2.86651932
19Stenosis of the external auditory canal (HP:0000402)2.83708849
20IgM deficiency (HP:0002850)2.81622574
21Congenital, generalized hypertrichosis (HP:0004540)2.72344494
22Trismus (HP:0000211)2.69268687
23Chromsome breakage (HP:0040012)2.67669051
24Woolly hair (HP:0002224)2.64634987
25Oral leukoplakia (HP:0002745)2.52541516
26Multiple enchondromatosis (HP:0005701)2.51129362
27Selective tooth agenesis (HP:0001592)2.50085672
28* Depressed nasal ridge (HP:0000457)2.50044666
29Chromosomal breakage induced by crosslinking agents (HP:0003221)2.46872206
30Basal cell carcinoma (HP:0002671)2.44803636
31Asplenia (HP:0001746)2.41868311
32Lipid accumulation in hepatocytes (HP:0006561)2.40417550
33Chronic otitis media (HP:0000389)2.37159823
34Recurrent bronchitis (HP:0002837)2.36391457
35Mitochondrial inheritance (HP:0001427)2.26094182
36* Thick lower lip vermilion (HP:0000179)2.25599453
37Aplasia/Hypoplasia of the spleen (HP:0010451)2.23866365
38Missing ribs (HP:0000921)2.15216357
39Poikiloderma (HP:0001029)2.13229183
40Cerebral edema (HP:0002181)2.12909383
41* Migraine (HP:0002076)2.12861591
42Progressive macrocephaly (HP:0004481)2.12501372
43Impulsivity (HP:0100710)2.11737867
44Abnormality of the diencephalon (HP:0010662)2.10551785
45Rib fusion (HP:0000902)2.09967439
46Increased intramyocellular lipid droplets (HP:0012240)2.08390496
47Abnormality of DNA repair (HP:0003254)2.07974094
48Myelodysplasia (HP:0002863)2.07744829
49* Abnormality of reticulocytes (HP:0004312)2.05294859
50Triphalangeal thumb (HP:0001199)2.04384699
51Abnormality of cochlea (HP:0000375)2.03120463
52Proximal placement of thumb (HP:0009623)2.03031660
53Absent septum pellucidum (HP:0001331)2.02384119
54Microvesicular hepatic steatosis (HP:0001414)2.01883024
55Hypoplasia of the radius (HP:0002984)2.01685295
56Neoplasm of the pancreas (HP:0002894)2.00828842
57Fragile nails (HP:0001808)1.99846977
58Overriding aorta (HP:0002623)1.99670643
59Renal duplication (HP:0000075)1.99372267
60Increased CSF lactate (HP:0002490)1.98335251
61Glossoptosis (HP:0000162)1.98268072
62Rough bone trabeculation (HP:0100670)1.98205776
63Maternal diabetes (HP:0009800)1.96528032
64T lymphocytopenia (HP:0005403)1.95466006
65Atresia of the external auditory canal (HP:0000413)1.94861163
66Lymphoma (HP:0002665)1.94464058
67Abnormality of T cells (HP:0002843)1.93203272
68Vertebral hypoplasia (HP:0008417)1.91493968
69Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.91493968
70Nasolacrimal duct obstruction (HP:0000579)1.90941328
71Abnormality of the distal phalanx of the thumb (HP:0009617)1.88104006
72Deviation of the thumb (HP:0009603)1.87954386
73Bicuspid aortic valve (HP:0001647)1.87577351
74Recurrent viral infections (HP:0004429)1.87341283
75Elevated erythrocyte sedimentation rate (HP:0003565)1.87003903
76Rectal prolapse (HP:0002035)1.86407076
77Aplasia/Hypoplasia of the thymus (HP:0010515)1.85779236
78Facial cleft (HP:0002006)1.85710464
79Panhypogammaglobulinemia (HP:0003139)1.85013469
80Abnormality of the septum pellucidum (HP:0007375)1.84806740
81Squamous cell carcinoma (HP:0002860)1.83408996
82Leukodystrophy (HP:0002415)1.83051881
83Increased hepatocellular lipid droplets (HP:0006565)1.82635509
84Abnormality of the preputium (HP:0100587)1.81023377
85High anterior hairline (HP:0009890)1.80881916
86B lymphocytopenia (HP:0010976)1.80879941
87Abnormality of B cell number (HP:0010975)1.80879941
88Rectal fistula (HP:0100590)1.80308124
89Rectovaginal fistula (HP:0000143)1.80308124
90Amaurosis fugax (HP:0100576)1.79575788
91Breast hypoplasia (HP:0003187)1.79435096
92Pili torti (HP:0003777)1.79391602
93Pustule (HP:0200039)1.78734042
94Sparse lateral eyebrow (HP:0005338)1.77651906
95Microretrognathia (HP:0000308)1.77583635
96Abnormality of the phalanges of the hallux (HP:0010057)1.77135674
97Cleft eyelid (HP:0000625)1.76326576
98Abnormality of T cell number (HP:0011839)1.76255561
99Elfin facies (HP:0004428)1.75510517
100Biliary tract neoplasm (HP:0100574)1.74720199
101Abnormality of T cell physiology (HP:0011840)1.74684852
102Abnormality of the lacrimal duct (HP:0011481)1.73688295
103Ependymoma (HP:0002888)1.73315452
104Medulloblastoma (HP:0002885)1.73239083
105Morphological abnormality of the inner ear (HP:0011390)1.73020040
106Increased nuchal translucency (HP:0010880)1.70694611
107Exertional dyspnea (HP:0002875)1.70326206
108Sparse scalp hair (HP:0002209)1.70264863
109Nasal polyposis (HP:0100582)1.69691304
110Hepatocellular necrosis (HP:0001404)1.68853196
111Deep palmar crease (HP:0006191)1.68702254
112Abnormal number of incisors (HP:0011064)1.68467428
113Rhabdomyosarcoma (HP:0002859)1.66185162
114Gastrointestinal inflammation (HP:0004386)1.65909626
115Metaphyseal cupping (HP:0003021)1.65652158
116Premature graying of hair (HP:0002216)1.65611582
117Abnormal tarsal ossification (HP:0008369)1.65083286
118Birth length less than 3rd percentile (HP:0003561)1.64898522
119Diastasis recti (HP:0001540)1.64812026
120Hyperglycinemia (HP:0002154)1.64377893
121Cellulitis (HP:0100658)1.64137063
122Increased muscle lipid content (HP:0009058)1.63353707
123Progressive muscle weakness (HP:0003323)1.62746288
124Abnormality of the calcaneus (HP:0008364)1.62385711
125Blepharitis (HP:0000498)1.61798894
126Acute lymphatic leukemia (HP:0006721)1.60926141
127Sparse eyelashes (HP:0000653)1.60759121
128Calcaneovalgus deformity (HP:0001848)1.60552405
129Papilloma (HP:0012740)1.60255473
130Verrucae (HP:0200043)1.60255473
131Hyperacusis (HP:0010780)1.60241388
132Hyperthyroidism (HP:0000836)1.60045190
133Agammaglobulinemia (HP:0004432)1.59928330
134Petechiae (HP:0000967)1.59587487
135Milia (HP:0001056)1.59311067
136Renal Fanconi syndrome (HP:0001994)1.59153608
137Cellular immunodeficiency (HP:0005374)1.58400706
138Ridged nail (HP:0001807)1.58304569
139Abnormality of cells of the lymphoid lineage (HP:0012140)1.58050175
140Molar tooth sign on MRI (HP:0002419)1.57728482
141Abnormality of midbrain morphology (HP:0002418)1.57728482
142Concave nail (HP:0001598)1.56911696
143Agnosia (HP:0010524)1.56709324
144Inflammation of the large intestine (HP:0002037)1.56545222
145Deep philtrum (HP:0002002)1.56111739
146Esophageal atresia (HP:0002032)1.55832498
147Aplasia cutis congenita (HP:0001057)1.55689135
148Partial duplication of the phalanx of hand (HP:0009999)1.55579581
149Premature ovarian failure (HP:0008209)1.55034065
150IgG deficiency (HP:0004315)1.53575509
151Entropion (HP:0000621)1.53478778
152Neoplasm of the colon (HP:0100273)1.53144627
153Lymphopenia (HP:0001888)1.52827444
154Horseshoe kidney (HP:0000085)1.52701365
155Respiratory difficulties (HP:0002880)1.51902619
156* Short nose (HP:0003196)1.51291532
157Carpal bone hypoplasia (HP:0001498)1.51187522
158Increased density of long bones (HP:0006392)1.51157362
159Insomnia (HP:0100785)1.50231086
160Forearm undergrowth (HP:0009821)1.49782822
161Abnormality of the nasolacrimal system (HP:0000614)1.48501577
162Truncus arteriosus (HP:0001660)1.47288843
163Hepatic necrosis (HP:0002605)1.46914380
164Patellar dislocation (HP:0002999)1.46677714
165Intestinal fistula (HP:0100819)1.46274583
166Progressive external ophthalmoplegia (HP:0000590)1.45905067
167Aplasia/Hypoplasia of the uvula (HP:0010293)1.45190445
168Vaginal fistula (HP:0004320)1.45167079
169Anophthalmia (HP:0000528)1.41007006

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.32056744
2EEF2K3.27046591
3TLK13.16588552
4RPS6KB22.86090586
5LRRK22.85217960
6WEE12.71387726
7VRK22.42154528
8MAP4K12.37931751
9CDC72.35946209
10BUB12.15930224
11TGFBR12.11957892
12PASK2.07971409
13NEK21.95265894
14MST41.91956927
15ICK1.90451798
16SMG11.88017862
17MAP3K101.83642108
18DYRK31.82915907
19SRPK11.82786122
20PKN21.79645580
21RPS6KA41.78271607
22STK101.77014990
23TYRO31.75951195
24EPHB21.72181793
25EIF2AK11.66038836
26VRK11.57648914
27WNK41.56038820
28AURKB1.50708158
29PNCK1.45150390
30FLT31.43665200
31MAPKAPK31.40248533
32CDK71.39154875
33PLK41.37743654
34PIM21.34914623
35NEK11.33721232
36MKNK11.33220907
37CDK121.30705804
38ZAK1.29941888
39ACVR1B1.29715205
40BTK1.24237856
41CDK41.23377653
42CDK81.21684926
43GRK61.18595883
44PIM11.18139601
45ILK1.16131855
46TAF11.13810809
47TEC1.13647137
48MAP3K81.12825698
49TSSK61.11757009
50BRSK21.09789366
51SCYL21.08285923
52TYK21.07572410
53BRAF1.04523220
54TESK21.03488583
55TTK1.01291322
56STK160.99673411
57NLK0.99559530
58CDK60.99223466
59PLK10.98018885
60ATR0.97899646
61LATS20.97556422
62EIF2AK30.95828148
63KDR0.92065474
64BLK0.91103883
65CDK190.90970817
66ZAP700.89175845
67PAK40.87170394
68CSNK1E0.85123185
69BRSK10.84339486
70EPHA20.82249587
71MAP3K30.82114313
72DMPK0.80969448
73STK40.80602489
74MKNK20.77285466
75WNK10.76874216
76ITK0.76489732
77MST1R0.75968227
78KIT0.75918076
79CHEK10.75351816
80CSNK2A20.74499243
81RPS6KA50.74477420
82LATS10.74233862
83IKBKB0.71920013
84STK30.70885180
85JAK30.70140728
86MTOR0.69070952
87IRAK30.68637113
88DYRK20.68002477
89CDK10.67195495
90PAK20.65913108
91CLK10.65792069
92RPS6KL10.65480326
93STK240.65473095
94MAP2K30.65023599
95AURKA0.64572994
96ALK0.63165573
97CSF1R0.62811351
98MAPK150.62748794
99DYRK1B0.61903949
100LCK0.61481778
101RPS6KA60.61276599
102TRIB30.58819740
103NME10.57773627
104SYK0.56998511
105TGFBR20.56747915
106PDK20.56379424
107CHEK20.56199732
108CDK30.56015824
109MAP2K20.55556457
110CDK90.55534397
111ATM0.53811766
112CDK20.52750495
113CSNK2A10.51011496
114CDK11A0.48375529
115DAPK30.47977114
116IKBKE0.45595249
117ABL20.43465108
118TBK10.42511169
119PRPF4B0.42204610
120BRD40.41876484
121AKT10.41202702
122LYN0.40429336
123TXK0.39704415
124MELK0.39652736
125MAP3K110.39153946
126MAPK140.39051506
127PRKDC0.38267388
128PTK60.37703415
129PAK10.36517342
130RPS6KA10.35721651
131IRAK20.35421767
132HCK0.34751181
133PLK30.34639390
134MAPKAPK20.34631353
135CCNB10.33600593
136PBK0.33572751
137TRPM70.33005543
138TTN0.32093189
139RPS6KC10.31549212
140AKT20.30078414
141PRKCI0.28555262
142KSR10.28487314
143MARK20.27737114
144MAPKAPK50.27657762

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030107.85015802
2DNA replication_Homo sapiens_hsa030303.70996955
3Spliceosome_Homo sapiens_hsa030403.11495659
4Mismatch repair_Homo sapiens_hsa034303.10442223
5RNA polymerase_Homo sapiens_hsa030202.60748784
6Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.58123624
7Homologous recombination_Homo sapiens_hsa034402.30722825
8RNA transport_Homo sapiens_hsa030132.28178488
9Proteasome_Homo sapiens_hsa030502.15652181
10Nucleotide excision repair_Homo sapiens_hsa034202.14177949
11Base excision repair_Homo sapiens_hsa034102.09493890
12Pyrimidine metabolism_Homo sapiens_hsa002401.87320427
13Cardiac muscle contraction_Homo sapiens_hsa042601.77814356
14One carbon pool by folate_Homo sapiens_hsa006701.76858234
15Non-homologous end-joining_Homo sapiens_hsa034501.75547854
16Primary immunodeficiency_Homo sapiens_hsa053401.70982654
17Cell cycle_Homo sapiens_hsa041101.70090509
18Systemic lupus erythematosus_Homo sapiens_hsa053221.54844828
19Fanconi anemia pathway_Homo sapiens_hsa034601.50251431
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.49671898
21RNA degradation_Homo sapiens_hsa030181.45963200
22Antigen processing and presentation_Homo sapiens_hsa046121.45525682
23p53 signaling pathway_Homo sapiens_hsa041151.42755046
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.29563615
25mRNA surveillance pathway_Homo sapiens_hsa030151.29248737
26Herpes simplex infection_Homo sapiens_hsa051681.18022819
27Basal transcription factors_Homo sapiens_hsa030221.16036374
28Protein export_Homo sapiens_hsa030601.11434471
29Cyanoamino acid metabolism_Homo sapiens_hsa004601.11242518
30Epstein-Barr virus infection_Homo sapiens_hsa051691.09530528
31Viral carcinogenesis_Homo sapiens_hsa052031.02747508
32Hematopoietic cell lineage_Homo sapiens_hsa046401.01973485
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.97961417
34Transcriptional misregulation in cancer_Homo sapiens_hsa052020.96277804
35Small cell lung cancer_Homo sapiens_hsa052220.94982178
36HTLV-I infection_Homo sapiens_hsa051660.91620143
37Thyroid cancer_Homo sapiens_hsa052160.88946812
38Biosynthesis of amino acids_Homo sapiens_hsa012300.84011976
39B cell receptor signaling pathway_Homo sapiens_hsa046620.80599607
40NF-kappa B signaling pathway_Homo sapiens_hsa040640.80271826
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.78587998
42Measles_Homo sapiens_hsa051620.78117812
43Intestinal immune network for IgA production_Homo sapiens_hsa046720.77414286
44Purine metabolism_Homo sapiens_hsa002300.74316108
45Sulfur relay system_Homo sapiens_hsa041220.71936939
46MicroRNAs in cancer_Homo sapiens_hsa052060.71686448
47Pyruvate metabolism_Homo sapiens_hsa006200.71680037
48Parkinsons disease_Homo sapiens_hsa050120.71548925
49Hedgehog signaling pathway_Homo sapiens_hsa043400.70888686
50T cell receptor signaling pathway_Homo sapiens_hsa046600.70498053
51Huntingtons disease_Homo sapiens_hsa050160.68655322
52Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.68281746
53Basal cell carcinoma_Homo sapiens_hsa052170.67704173
54Chronic myeloid leukemia_Homo sapiens_hsa052200.67415507
55Carbon metabolism_Homo sapiens_hsa012000.67195031
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.67050631
57Notch signaling pathway_Homo sapiens_hsa043300.66997677
58Apoptosis_Homo sapiens_hsa042100.65669428
59Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65387407
60Acute myeloid leukemia_Homo sapiens_hsa052210.64430685
61Jak-STAT signaling pathway_Homo sapiens_hsa046300.61900243
62Leukocyte transendothelial migration_Homo sapiens_hsa046700.61335025
63Hepatitis B_Homo sapiens_hsa051610.61284637
64Legionellosis_Homo sapiens_hsa051340.60496453
65Alcoholism_Homo sapiens_hsa050340.58447329
66NOD-like receptor signaling pathway_Homo sapiens_hsa046210.56807125
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.56653244
68Leishmaniasis_Homo sapiens_hsa051400.55562510
69Colorectal cancer_Homo sapiens_hsa052100.55437080
70Oxidative phosphorylation_Homo sapiens_hsa001900.55048232
71Toxoplasmosis_Homo sapiens_hsa051450.53462152
72Bladder cancer_Homo sapiens_hsa052190.52415607
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.50321056
74Viral myocarditis_Homo sapiens_hsa054160.49775356
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49215751
76Wnt signaling pathway_Homo sapiens_hsa043100.48690110
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.48631113
78Pentose phosphate pathway_Homo sapiens_hsa000300.47959118
79Shigellosis_Homo sapiens_hsa051310.47674954
80Pathways in cancer_Homo sapiens_hsa052000.47392217
81Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.45509498
82RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.45457872
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.43640905
84Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43107988
85TGF-beta signaling pathway_Homo sapiens_hsa043500.42829493
86Influenza A_Homo sapiens_hsa051640.42553463
87AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.41819360
88Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41167346
89Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.40331752
90Folate biosynthesis_Homo sapiens_hsa007900.39908962
91Osteoclast differentiation_Homo sapiens_hsa043800.39870537
92Metabolic pathways_Homo sapiens_hsa011000.39746799
93Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39619957
94Proteoglycans in cancer_Homo sapiens_hsa052050.38248312
95Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.38031320
96Adherens junction_Homo sapiens_hsa045200.37308904
97Platelet activation_Homo sapiens_hsa046110.36803990
98Renal cell carcinoma_Homo sapiens_hsa052110.36785241
99N-Glycan biosynthesis_Homo sapiens_hsa005100.36184358
100Asthma_Homo sapiens_hsa053100.34434902
101Allograft rejection_Homo sapiens_hsa053300.34297937
102Hippo signaling pathway_Homo sapiens_hsa043900.33637108
103Alzheimers disease_Homo sapiens_hsa050100.33535129
104Central carbon metabolism in cancer_Homo sapiens_hsa052300.33312967
105Prostate cancer_Homo sapiens_hsa052150.33239211
106Pancreatic cancer_Homo sapiens_hsa052120.33049042
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.32948005
108HIF-1 signaling pathway_Homo sapiens_hsa040660.30582050
109Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.29064992
110Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.28904668
111Non-small cell lung cancer_Homo sapiens_hsa052230.28838427
112Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.28202913
113ECM-receptor interaction_Homo sapiens_hsa045120.28122752
114Arginine and proline metabolism_Homo sapiens_hsa003300.27518030
115Oocyte meiosis_Homo sapiens_hsa041140.23736332
116Glutathione metabolism_Homo sapiens_hsa004800.23388409
117VEGF signaling pathway_Homo sapiens_hsa043700.23190252
118Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.22162264
119Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.18965217
120Vitamin digestion and absorption_Homo sapiens_hsa049770.18242489
121Melanoma_Homo sapiens_hsa052180.17750880
122Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17314997
123Fat digestion and absorption_Homo sapiens_hsa049750.17100054
124Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.14060015
125Propanoate metabolism_Homo sapiens_hsa006400.13056853
126ErbB signaling pathway_Homo sapiens_hsa040120.12340880
127Carbohydrate digestion and absorption_Homo sapiens_hsa049730.11215092
128Galactose metabolism_Homo sapiens_hsa000520.10536711
1292-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.09303436
130Melanogenesis_Homo sapiens_hsa049160.09026616
131mTOR signaling pathway_Homo sapiens_hsa041500.07761345
132Arginine biosynthesis_Homo sapiens_hsa002200.06182817
133Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.06097111
134Endometrial cancer_Homo sapiens_hsa052130.05656889
135Tyrosine metabolism_Homo sapiens_hsa003500.04874993

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