

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 9.16845120 |
| 2 | translational termination (GO:0006415) | 8.76644636 |
| 3 | ribosomal small subunit biogenesis (GO:0042274) | 8.44953324 |
| 4 | maturation of SSU-rRNA (GO:0030490) | 8.25798270 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 7.78498116 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 7.35368039 |
| 7 | cotranslational protein targeting to membrane (GO:0006613) | 7.27788831 |
| 8 | translational elongation (GO:0006414) | 7.25214786 |
| 9 | protein targeting to ER (GO:0045047) | 7.23005326 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.95071562 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 6.75822984 |
| 12 | cellular protein complex disassembly (GO:0043624) | 6.60576618 |
| 13 | viral life cycle (GO:0019058) | 6.53810641 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.44013634 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.80122673 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 5.80122673 |
| 17 | protein complex disassembly (GO:0043241) | 5.58621258 |
| 18 | translational initiation (GO:0006413) | 5.51675436 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.43146381 |
| 20 | macromolecular complex disassembly (GO:0032984) | 5.33916637 |
| 21 | protein targeting to membrane (GO:0006612) | 5.02520208 |
| 22 | ribosomal large subunit biogenesis (GO:0042273) | 4.90666950 |
| 23 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.56321285 |
| 24 | protein neddylation (GO:0045116) | 4.50182500 |
| 25 | behavioral response to nicotine (GO:0035095) | 4.38718644 |
| 26 | translation (GO:0006412) | 4.37222938 |
| 27 | mRNA catabolic process (GO:0006402) | 4.31467179 |
| 28 | NADH dehydrogenase complex assembly (GO:0010257) | 4.29056625 |
| 29 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.29056625 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.29056625 |
| 31 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.19948076 |
| 32 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.13852402 |
| 33 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.13852402 |
| 34 | chaperone-mediated protein transport (GO:0072321) | 4.11181296 |
| 35 | respiratory electron transport chain (GO:0022904) | 4.02020422 |
| 36 | electron transport chain (GO:0022900) | 3.99465084 |
| 37 | protein complex biogenesis (GO:0070271) | 3.92051995 |
| 38 | RNA catabolic process (GO:0006401) | 3.91887799 |
| 39 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.81583739 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.74459455 |
| 41 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.74459455 |
| 42 | nonmotile primary cilium assembly (GO:0035058) | 3.69972773 |
| 43 | cellular component biogenesis (GO:0044085) | 3.64241129 |
| 44 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.60841715 |
| 45 | GTP biosynthetic process (GO:0006183) | 3.49860299 |
| 46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.47390319 |
| 47 | establishment of protein localization to membrane (GO:0090150) | 3.37281416 |
| 48 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.30269734 |
| 49 | cell proliferation in forebrain (GO:0021846) | 3.25149087 |
| 50 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.24163096 |
| 51 | ATP biosynthetic process (GO:0006754) | 3.24083240 |
| 52 | protein targeting (GO:0006605) | 3.19302314 |
| 53 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.16982591 |
| 54 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.13802528 |
| 55 | hydrogen ion transmembrane transport (GO:1902600) | 3.07289485 |
| 56 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.06656868 |
| 57 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.06075865 |
| 58 | regulation of cilium movement (GO:0003352) | 3.04995810 |
| 59 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.98610567 |
| 60 | establishment of protein localization to organelle (GO:0072594) | 2.97111187 |
| 61 | UTP biosynthetic process (GO:0006228) | 2.96172132 |
| 62 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.95680021 |
| 63 | tongue development (GO:0043586) | 2.94913614 |
| 64 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.89303013 |
| 65 | spinal cord association neuron differentiation (GO:0021527) | 2.88159564 |
| 66 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.87292281 |
| 67 | cardiovascular system development (GO:0072358) | 2.84992779 |
| 68 | piRNA metabolic process (GO:0034587) | 2.82474031 |
| 69 | rRNA processing (GO:0006364) | 2.82293694 |
| 70 | gonadal mesoderm development (GO:0007506) | 2.81818801 |
| 71 | rRNA metabolic process (GO:0016072) | 2.81479386 |
| 72 | proton transport (GO:0015992) | 2.81434621 |
| 73 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.81326349 |
| 74 | kynurenine metabolic process (GO:0070189) | 2.80467345 |
| 75 | UTP metabolic process (GO:0046051) | 2.80141620 |
| 76 | organelle disassembly (GO:1903008) | 2.77575508 |
| 77 | aldehyde catabolic process (GO:0046185) | 2.77249291 |
| 78 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.77237569 |
| 79 | hydrogen transport (GO:0006818) | 2.74541800 |
| 80 | pattern specification involved in kidney development (GO:0061004) | 2.70452548 |
| 81 | protein localization to membrane (GO:0072657) | 2.70360849 |
| 82 | somite development (GO:0061053) | 2.69701302 |
| 83 | segment specification (GO:0007379) | 2.68977344 |
| 84 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.66792979 |
| 85 | detection of light stimulus involved in visual perception (GO:0050908) | 2.66792979 |
| 86 | neuron fate determination (GO:0048664) | 2.66115518 |
| 87 | rRNA catabolic process (GO:0016075) | 2.65481160 |
| 88 | DNA methylation involved in gamete generation (GO:0043046) | 2.63439628 |
| 89 | synaptic transmission, cholinergic (GO:0007271) | 2.61969572 |
| 90 | base-excision repair, AP site formation (GO:0006285) | 2.61768048 |
| 91 | intraciliary transport (GO:0042073) | 2.60207049 |
| 92 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.59046641 |
| 93 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 2.57398401 |
| 94 | regulation of microtubule-based movement (GO:0060632) | 2.56993182 |
| 95 | microtubule severing (GO:0051013) | 2.56730486 |
| 96 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.56099051 |
| 97 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.55164115 |
| 98 | viral protein processing (GO:0019082) | 2.55097543 |
| 99 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.53852803 |
| 100 | ncRNA 3-end processing (GO:0043628) | 2.50586919 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 7.74755470 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.44918521 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.27812490 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.25043775 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.57840934 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.54666581 |
| 7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.36104302 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.32187055 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.30344071 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.15922516 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.05528740 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.99858565 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.96010045 |
| 14 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.93683399 |
| 15 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.78451203 |
| 16 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.76657375 |
| 17 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.76100382 |
| 18 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.73955682 |
| 19 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.65551468 |
| 20 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.65006115 |
| 21 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.64558967 |
| 22 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.63730599 |
| 23 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.62880616 |
| 24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.54850867 |
| 25 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.54013528 |
| 26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.53766187 |
| 27 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.53549301 |
| 28 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.50490203 |
| 29 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.48851690 |
| 30 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.48780856 |
| 31 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.47815631 |
| 32 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.46883470 |
| 33 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.46141423 |
| 34 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.41658974 |
| 35 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.37868489 |
| 36 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.37216701 |
| 37 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.36178598 |
| 38 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35792520 |
| 39 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.34656583 |
| 40 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.32991233 |
| 41 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.26114475 |
| 42 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.25579537 |
| 43 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.25278263 |
| 44 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.24607403 |
| 45 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.24171988 |
| 46 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.24121484 |
| 47 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.23952633 |
| 48 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.22609413 |
| 49 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.21272679 |
| 50 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.21239428 |
| 51 | EWS_26573619_Chip-Seq_HEK293_Human | 1.17640637 |
| 52 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.16161478 |
| 53 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.14804025 |
| 54 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.13085379 |
| 55 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.10848362 |
| 56 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.10547389 |
| 57 | FUS_26573619_Chip-Seq_HEK293_Human | 1.09922842 |
| 58 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.08863514 |
| 59 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.08605553 |
| 60 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.08068811 |
| 61 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.07793641 |
| 62 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.06904361 |
| 63 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.06903445 |
| 64 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.06603780 |
| 65 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.06544375 |
| 66 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.06226353 |
| 67 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.06226353 |
| 68 | ERA_21632823_ChIP-Seq_H3396_Human | 1.05052927 |
| 69 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.04747580 |
| 70 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04185465 |
| 71 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04175252 |
| 72 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.03708404 |
| 73 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.03432176 |
| 74 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.02887770 |
| 75 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.02256084 |
| 76 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.02256084 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.02051620 |
| 78 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.01405606 |
| 79 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.00944173 |
| 80 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.99472360 |
| 81 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.99203269 |
| 82 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.98650992 |
| 83 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.97385483 |
| 84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.96092478 |
| 85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95908052 |
| 86 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.95475444 |
| 87 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.92914335 |
| 88 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.92517627 |
| 89 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.91864181 |
| 90 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.91658433 |
| 91 | NCOR_22424771_ChIP-Seq_293T_Human | 0.90138097 |
| 92 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90082152 |
| 93 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.88721001 |
| 94 | SA1_27219007_Chip-Seq_Bcells_Human | 0.88189009 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.87800659 |
| 96 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.87798876 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.87763887 |
| 98 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.87111149 |
| 99 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.86683517 |
| 100 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.86406590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.64419986 |
| 2 | MP0003787_abnormal_imprinting | 3.96719642 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.57224331 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.50624012 |
| 5 | MP0003878_abnormal_ear_physiology | 2.72930042 |
| 6 | MP0005377_hearing/vestibular/ear_phenot | 2.72930042 |
| 7 | MP0004142_abnormal_muscle_tone | 2.61186883 |
| 8 | MP0003646_muscle_fatigue | 2.55535628 |
| 9 | MP0008789_abnormal_olfactory_epithelium | 2.40487669 |
| 10 | MP0005394_taste/olfaction_phenotype | 2.08082261 |
| 11 | MP0005499_abnormal_olfactory_system | 2.08082261 |
| 12 | MP0003121_genomic_imprinting | 1.95194566 |
| 13 | MP0001293_anophthalmia | 1.85560244 |
| 14 | MP0001968_abnormal_touch/_nociception | 1.76022830 |
| 15 | MP0001440_abnormal_grooming_behavior | 1.75412809 |
| 16 | MP0001485_abnormal_pinna_reflex | 1.72729784 |
| 17 | MP0003122_maternal_imprinting | 1.71033955 |
| 18 | MP0006072_abnormal_retinal_apoptosis | 1.67158875 |
| 19 | MP0002272_abnormal_nervous_system | 1.66192420 |
| 20 | MP0002837_dystrophic_cardiac_calcinosis | 1.62634924 |
| 21 | MP0001529_abnormal_vocalization | 1.57436319 |
| 22 | MP0005551_abnormal_eye_electrophysiolog | 1.54113267 |
| 23 | MP0001984_abnormal_olfaction | 1.54083367 |
| 24 | MP0004885_abnormal_endolymph | 1.53895595 |
| 25 | MP0002736_abnormal_nociception_after | 1.53414051 |
| 26 | MP0001986_abnormal_taste_sensitivity | 1.52720475 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.52287237 |
| 28 | MP0000566_synostosis | 1.49303719 |
| 29 | MP0002653_abnormal_ependyma_morphology | 1.45851526 |
| 30 | MP0004742_abnormal_vestibular_system | 1.45546751 |
| 31 | MP0002163_abnormal_gland_morphology | 1.44873885 |
| 32 | MP0001348_abnormal_lacrimal_gland | 1.43239895 |
| 33 | MP0004145_abnormal_muscle_electrophysio | 1.42706102 |
| 34 | MP0003123_paternal_imprinting | 1.41335016 |
| 35 | MP0002102_abnormal_ear_morphology | 1.41160006 |
| 36 | MP0000049_abnormal_middle_ear | 1.40034700 |
| 37 | MP0005671_abnormal_response_to | 1.38018621 |
| 38 | MP0006276_abnormal_autonomic_nervous | 1.36762963 |
| 39 | MP0009046_muscle_twitch | 1.36262831 |
| 40 | MP0004147_increased_porphyrin_level | 1.32188109 |
| 41 | MP0008872_abnormal_physiological_respon | 1.26423013 |
| 42 | MP0008875_abnormal_xenobiotic_pharmacok | 1.26151105 |
| 43 | MP0003879_abnormal_hair_cell | 1.25934380 |
| 44 | MP0001970_abnormal_pain_threshold | 1.22985336 |
| 45 | MP0002822_catalepsy | 1.21307867 |
| 46 | MP0003186_abnormal_redox_activity | 1.20867227 |
| 47 | MP0009745_abnormal_behavioral_response | 1.15774460 |
| 48 | MP0005423_abnormal_somatic_nervous | 1.14379914 |
| 49 | MP0003136_yellow_coat_color | 1.13463871 |
| 50 | MP0002138_abnormal_hepatobiliary_system | 1.10888609 |
| 51 | MP0005195_abnormal_posterior_eye | 1.10768425 |
| 52 | MP0001905_abnormal_dopamine_level | 1.09797142 |
| 53 | MP0002557_abnormal_social/conspecific_i | 1.09479707 |
| 54 | MP0001486_abnormal_startle_reflex | 1.09398988 |
| 55 | MP0000778_abnormal_nervous_system | 1.08286730 |
| 56 | MP0000372_irregular_coat_pigmentation | 1.08217367 |
| 57 | MP0009764_decreased_sensitivity_to | 1.07554831 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.07493371 |
| 59 | MP0003567_abnormal_fetal_cardiomyocyte | 1.06884714 |
| 60 | MP0005645_abnormal_hypothalamus_physiol | 1.06875448 |
| 61 | MP0004133_heterotaxia | 1.05467126 |
| 62 | MP0002572_abnormal_emotion/affect_behav | 1.04585281 |
| 63 | MP0005253_abnormal_eye_physiology | 1.03796215 |
| 64 | MP0005389_reproductive_system_phenotype | 1.02982395 |
| 65 | MP0003635_abnormal_synaptic_transmissio | 1.02058190 |
| 66 | MP0002095_abnormal_skin_pigmentation | 1.01180588 |
| 67 | MP0002733_abnormal_thermal_nociception | 0.99387252 |
| 68 | MP0010030_abnormal_orbit_morphology | 0.99163811 |
| 69 | MP0002184_abnormal_innervation | 0.98046953 |
| 70 | MP0002234_abnormal_pharynx_morphology | 0.96121968 |
| 71 | MP0002752_abnormal_somatic_nervous | 0.94492933 |
| 72 | MP0002938_white_spotting | 0.93922536 |
| 73 | MP0003880_abnormal_central_pattern | 0.92290039 |
| 74 | MP0002160_abnormal_reproductive_system | 0.90441885 |
| 75 | MP0000026_abnormal_inner_ear | 0.90004737 |
| 76 | MP0005379_endocrine/exocrine_gland_phen | 0.89902508 |
| 77 | MP0002063_abnormal_learning/memory/cond | 0.87471963 |
| 78 | MP0001919_abnormal_reproductive_system | 0.86820489 |
| 79 | MP0002734_abnormal_mechanical_nocicepti | 0.86664144 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.85959996 |
| 81 | MP0000631_abnormal_neuroendocrine_gland | 0.85941299 |
| 82 | MP0008775_abnormal_heart_ventricle | 0.83709358 |
| 83 | MP0002064_seizures | 0.82383764 |
| 84 | MP0003011_delayed_dark_adaptation | 0.80626775 |
| 85 | MP0005174_abnormal_tail_pigmentation | 0.80219741 |
| 86 | MP0002067_abnormal_sensory_capabilities | 0.80142028 |
| 87 | MP0005083_abnormal_biliary_tract | 0.80026818 |
| 88 | MP0003718_maternal_effect | 0.78293109 |
| 89 | MP0001835_abnormal_antigen_presentation | 0.76491269 |
| 90 | MP0002735_abnormal_chemical_nociception | 0.75741353 |
| 91 | MP0002233_abnormal_nose_morphology | 0.72160436 |
| 92 | MP0001324_abnormal_eye_pigmentation | 0.70619039 |
| 93 | MP0001963_abnormal_hearing_physiology | 0.70006396 |
| 94 | MP0000230_abnormal_systemic_arterial | 0.69621082 |
| 95 | MP0005075_abnormal_melanosome_morpholog | 0.69271522 |
| 96 | MP0008995_early_reproductive_senescence | 0.68206027 |
| 97 | MP0000955_abnormal_spinal_cord | 0.67857038 |
| 98 | MP0002210_abnormal_sex_determination | 0.67217945 |
| 99 | MP0005386_behavior/neurological_phenoty | 0.66498552 |
| 100 | MP0004924_abnormal_behavior | 0.66498552 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 6.78868376 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.02321149 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.88750305 |
| 4 | Abnormal hemoglobin (HP:0011902) | 4.70619006 |
| 5 | Acute encephalopathy (HP:0006846) | 4.64821615 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.31449152 |
| 7 | Abnormality of midbrain morphology (HP:0002418) | 4.12220122 |
| 8 | Molar tooth sign on MRI (HP:0002419) | 4.12220122 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.95418237 |
| 10 | Macrocytic anemia (HP:0001972) | 3.91855989 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.87158230 |
| 12 | Pallor (HP:0000980) | 3.84730900 |
| 13 | Pancreatic fibrosis (HP:0100732) | 3.77396384 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.55220757 |
| 15 | Increased CSF lactate (HP:0002490) | 3.37077913 |
| 16 | Hepatocellular necrosis (HP:0001404) | 3.29278787 |
| 17 | Hyperglycinemia (HP:0002154) | 3.22686004 |
| 18 | Cerebral edema (HP:0002181) | 3.17639648 |
| 19 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.16058622 |
| 20 | Pancreatic cysts (HP:0001737) | 3.07928576 |
| 21 | Septo-optic dysplasia (HP:0100842) | 3.04064672 |
| 22 | Type II lissencephaly (HP:0007260) | 3.00639830 |
| 23 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.99268171 |
| 24 | Nephronophthisis (HP:0000090) | 2.98825496 |
| 25 | Hepatic necrosis (HP:0002605) | 2.93735083 |
| 26 | Asplenia (HP:0001746) | 2.77634457 |
| 27 | Medial flaring of the eyebrow (HP:0010747) | 2.74489716 |
| 28 | Optic disc pallor (HP:0000543) | 2.67561683 |
| 29 | Stenosis of the external auditory canal (HP:0000402) | 2.66068943 |
| 30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.65836946 |
| 31 | Rib fusion (HP:0000902) | 2.58044482 |
| 32 | Leukodystrophy (HP:0002415) | 2.52739287 |
| 33 | Cystic liver disease (HP:0006706) | 2.51468176 |
| 34 | Myokymia (HP:0002411) | 2.50709270 |
| 35 | Increased hepatocellular lipid droplets (HP:0006565) | 2.44597338 |
| 36 | True hermaphroditism (HP:0010459) | 2.44097876 |
| 37 | Abolished electroretinogram (ERG) (HP:0000550) | 2.43334178 |
| 38 | Absent thumb (HP:0009777) | 2.42428419 |
| 39 | Abnormality of the renal medulla (HP:0100957) | 2.38180201 |
| 40 | Congenital, generalized hypertrichosis (HP:0004540) | 2.38081542 |
| 41 | Lipid accumulation in hepatocytes (HP:0006561) | 2.36320346 |
| 42 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.30312086 |
| 43 | Hyperglycinuria (HP:0003108) | 2.29011332 |
| 44 | Anencephaly (HP:0002323) | 2.26244846 |
| 45 | Postaxial foot polydactyly (HP:0001830) | 2.25456521 |
| 46 | Abnormality of reticulocytes (HP:0004312) | 2.23483988 |
| 47 | Sclerocornea (HP:0000647) | 2.21115693 |
| 48 | Renal Fanconi syndrome (HP:0001994) | 2.20672685 |
| 49 | Cerebellar dysplasia (HP:0007033) | 2.18526855 |
| 50 | Supernumerary spleens (HP:0009799) | 2.11695195 |
| 51 | Increased intramyocellular lipid droplets (HP:0012240) | 2.11217328 |
| 52 | Pendular nystagmus (HP:0012043) | 2.11138702 |
| 53 | Anophthalmia (HP:0000528) | 2.11135171 |
| 54 | Gait imbalance (HP:0002141) | 2.09265586 |
| 55 | Lactic acidosis (HP:0003128) | 2.08634932 |
| 56 | Congenital stationary night blindness (HP:0007642) | 2.07719035 |
| 57 | Tachypnea (HP:0002789) | 2.06859741 |
| 58 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.05429355 |
| 59 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.05429355 |
| 60 | 3-Methylglutaconic aciduria (HP:0003535) | 2.05329910 |
| 61 | Congenital hepatic fibrosis (HP:0002612) | 2.00702841 |
| 62 | Polydipsia (HP:0001959) | 1.97627363 |
| 63 | Abnormal drinking behavior (HP:0030082) | 1.97627363 |
| 64 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.97053720 |
| 65 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.96229270 |
| 66 | Hypoplasia of the ulna (HP:0003022) | 1.96158934 |
| 67 | Hyperthyroidism (HP:0000836) | 1.95936436 |
| 68 | Hypoplasia of the radius (HP:0002984) | 1.94059267 |
| 69 | Respiratory failure (HP:0002878) | 1.93396907 |
| 70 | Abnormality of the renal cortex (HP:0011035) | 1.93192788 |
| 71 | Congenital primary aphakia (HP:0007707) | 1.92396634 |
| 72 | Nephrogenic diabetes insipidus (HP:0009806) | 1.91012287 |
| 73 | Lethargy (HP:0001254) | 1.90740280 |
| 74 | Increased serum lactate (HP:0002151) | 1.90615365 |
| 75 | Depressed nasal ridge (HP:0000457) | 1.88320398 |
| 76 | Polyphagia (HP:0002591) | 1.87623898 |
| 77 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.87437367 |
| 78 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.87437367 |
| 79 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.85727693 |
| 80 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.85615380 |
| 81 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.82390395 |
| 82 | Abnormality of glycine metabolism (HP:0010895) | 1.82390395 |
| 83 | Agitation (HP:0000713) | 1.81972020 |
| 84 | Abnormality of the corticospinal tract (HP:0002492) | 1.80017447 |
| 85 | Renal cortical cysts (HP:0000803) | 1.78628402 |
| 86 | Increased muscle lipid content (HP:0009058) | 1.78266883 |
| 87 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.77225119 |
| 88 | Growth hormone deficiency (HP:0000824) | 1.76642317 |
| 89 | Bifid tongue (HP:0010297) | 1.75859335 |
| 90 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.75329646 |
| 91 | Pachygyria (HP:0001302) | 1.74582040 |
| 92 | Lissencephaly (HP:0001339) | 1.73808483 |
| 93 | Postaxial hand polydactyly (HP:0001162) | 1.73336660 |
| 94 | Abnormality of DNA repair (HP:0003254) | 1.72354377 |
| 95 | Absent septum pellucidum (HP:0001331) | 1.72013582 |
| 96 | Abnormal ciliary motility (HP:0012262) | 1.71731669 |
| 97 | Abnormal biliary tract physiology (HP:0012439) | 1.70682863 |
| 98 | Bile duct proliferation (HP:0001408) | 1.70682863 |
| 99 | Horseshoe kidney (HP:0000085) | 1.69661068 |
| 100 | Forearm undergrowth (HP:0009821) | 1.69466085 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 4.28760893 |
| 2 | STK16 | 2.78977042 |
| 3 | PINK1 | 2.72714221 |
| 4 | BCKDK | 2.60744356 |
| 5 | GRK1 | 2.53252759 |
| 6 | ADRBK2 | 2.51645098 |
| 7 | DYRK2 | 2.45181884 |
| 8 | STK39 | 2.43511649 |
| 9 | TIE1 | 2.26227546 |
| 10 | WNK1 | 2.26042611 |
| 11 | CDK19 | 2.12680443 |
| 12 | TLK1 | 2.06305005 |
| 13 | TAOK3 | 1.95885119 |
| 14 | LRRK2 | 1.90796037 |
| 15 | FRK | 1.70112270 |
| 16 | TXK | 1.63343745 |
| 17 | MAP3K11 | 1.51987863 |
| 18 | TYRO3 | 1.49235922 |
| 19 | OXSR1 | 1.46781527 |
| 20 | MAP4K2 | 1.41478194 |
| 21 | BMPR1B | 1.38294173 |
| 22 | ZAK | 1.36220239 |
| 23 | EPHB2 | 1.33516117 |
| 24 | PDK2 | 1.31046991 |
| 25 | TEC | 1.28980142 |
| 26 | PAK3 | 1.23057601 |
| 27 | PRKCG | 1.20072801 |
| 28 | BRAF | 1.19841671 |
| 29 | NUAK1 | 1.19021402 |
| 30 | PHKG2 | 1.17537336 |
| 31 | PHKG1 | 1.17537336 |
| 32 | RPS6KA6 | 1.15066359 |
| 33 | DAPK3 | 1.12708129 |
| 34 | ACVR1B | 1.06570109 |
| 35 | PIK3CA | 1.04205628 |
| 36 | EPHA4 | 1.04126664 |
| 37 | WNK3 | 1.03194758 |
| 38 | PLK4 | 1.02210843 |
| 39 | RPS6KL1 | 0.98734097 |
| 40 | RPS6KC1 | 0.98734097 |
| 41 | IKBKB | 0.94412947 |
| 42 | BMPR2 | 0.94266700 |
| 43 | DAPK2 | 0.94101472 |
| 44 | ADRBK1 | 0.92932535 |
| 45 | PRKCQ | 0.91506522 |
| 46 | MINK1 | 0.91437332 |
| 47 | PIM2 | 0.90414950 |
| 48 | NEK1 | 0.88546213 |
| 49 | NTRK2 | 0.88269880 |
| 50 | DMPK | 0.84835753 |
| 51 | MAP2K7 | 0.84697583 |
| 52 | CAMK1 | 0.84611495 |
| 53 | INSRR | 0.84183572 |
| 54 | ABL2 | 0.84162834 |
| 55 | CAMKK2 | 0.83663138 |
| 56 | RPS6KA5 | 0.82413128 |
| 57 | MAP3K4 | 0.79299933 |
| 58 | CSNK2A2 | 0.79151799 |
| 59 | TGFBR1 | 0.78894487 |
| 60 | NME2 | 0.78363068 |
| 61 | MARK1 | 0.77331256 |
| 62 | PRKACA | 0.74538273 |
| 63 | CSNK1G2 | 0.74377244 |
| 64 | BTK | 0.72510297 |
| 65 | CDC7 | 0.72124819 |
| 66 | NME1 | 0.71198930 |
| 67 | MAP4K1 | 0.70511717 |
| 68 | RPS6KA2 | 0.69696364 |
| 69 | PRKCZ | 0.68370240 |
| 70 | MAPK13 | 0.66612862 |
| 71 | CASK | 0.65192143 |
| 72 | PRKCI | 0.64816224 |
| 73 | MAP2K2 | 0.62313308 |
| 74 | MKNK2 | 0.62248938 |
| 75 | ITK | 0.61421640 |
| 76 | CSNK1E | 0.60716569 |
| 77 | CDK8 | 0.59049414 |
| 78 | ARAF | 0.57799779 |
| 79 | NEK2 | 0.57042705 |
| 80 | OBSCN | 0.56565925 |
| 81 | SIK2 | 0.55569897 |
| 82 | RPS6KA1 | 0.54490206 |
| 83 | MAPK15 | 0.54475655 |
| 84 | CSNK1G1 | 0.53407892 |
| 85 | AURKA | 0.52763628 |
| 86 | PAK6 | 0.51227665 |
| 87 | STK11 | 0.50797223 |
| 88 | PRKCH | 0.49702523 |
| 89 | PNCK | 0.48030858 |
| 90 | CSNK2A1 | 0.47448385 |
| 91 | CSNK1G3 | 0.46682375 |
| 92 | SGK1 | 0.46189916 |
| 93 | PRKCE | 0.46069288 |
| 94 | CAMK2A | 0.44919633 |
| 95 | CHEK2 | 0.44758365 |
| 96 | KIT | 0.44353556 |
| 97 | AURKB | 0.43588730 |
| 98 | GRK7 | 0.43222678 |
| 99 | DAPK1 | 0.43183338 |
| 100 | MAPKAPK3 | 0.42224956 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.09057919 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.31998602 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.49854004 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.92971597 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.81449681 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.53431806 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.50611685 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.49774042 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.19952445 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.19010361 |
| 11 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.12942973 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.11657797 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.05574373 |
| 14 | Allograft rejection_Homo sapiens_hsa05330 | 1.97927686 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.86500454 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.82804335 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.74476777 |
| 18 | Proteasome_Homo sapiens_hsa03050 | 1.69923884 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.67572768 |
| 20 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.61874570 |
| 21 | Nicotine addiction_Homo sapiens_hsa05033 | 1.53484166 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.51947375 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.43061138 |
| 24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.32580826 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.26309879 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.21565814 |
| 27 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.18273776 |
| 28 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.11518724 |
| 29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.10920781 |
| 30 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06568950 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.01628447 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.99842140 |
| 33 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.98391874 |
| 34 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.97579057 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.93318198 |
| 36 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.88701146 |
| 37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.82436821 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.82087608 |
| 39 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.80974749 |
| 40 | Peroxisome_Homo sapiens_hsa04146 | 0.78788630 |
| 41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.78295008 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.76398428 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.75614095 |
| 44 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.75066510 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.74499050 |
| 46 | Olfactory transduction_Homo sapiens_hsa04740 | 0.74097839 |
| 47 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.72670020 |
| 48 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.72325867 |
| 49 | Morphine addiction_Homo sapiens_hsa05032 | 0.72115677 |
| 50 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.71489480 |
| 51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.70174674 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.68087978 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63302136 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61730428 |
| 55 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60199460 |
| 56 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.60160552 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.58797887 |
| 58 | Taste transduction_Homo sapiens_hsa04742 | 0.57195983 |
| 59 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56925082 |
| 60 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.54949579 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53551520 |
| 62 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.51376926 |
| 63 | RNA transport_Homo sapiens_hsa03013 | 0.51351970 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.49991327 |
| 65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48921928 |
| 66 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48769624 |
| 67 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.48479472 |
| 68 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.47985807 |
| 69 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46626363 |
| 70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.46363619 |
| 71 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.46029094 |
| 72 | GABAergic synapse_Homo sapiens_hsa04727 | 0.45940037 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 0.44868867 |
| 74 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.44222885 |
| 75 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.42737298 |
| 76 | Spliceosome_Homo sapiens_hsa03040 | 0.41647088 |
| 77 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40147389 |
| 78 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.40129085 |
| 79 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.39562340 |
| 80 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37399775 |
| 81 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.36829902 |
| 82 | Mineral absorption_Homo sapiens_hsa04978 | 0.35517625 |
| 83 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.34974028 |
| 84 | Insulin secretion_Homo sapiens_hsa04911 | 0.33560304 |
| 85 | Base excision repair_Homo sapiens_hsa03410 | 0.33062916 |
| 86 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32520986 |
| 87 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.32238831 |
| 88 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.31323723 |
| 89 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.31055894 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.29223317 |
| 91 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.28109063 |
| 92 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.26231637 |
| 93 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.25339780 |
| 94 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.23334814 |
| 95 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22066260 |
| 96 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.21235456 |
| 97 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.19091330 |
| 98 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.19017378 |
| 99 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.17768573 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.15749808 |

