RPS24P6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)9.16845120
2translational termination (GO:0006415)8.76644636
3ribosomal small subunit biogenesis (GO:0042274)8.44953324
4maturation of SSU-rRNA (GO:0030490)8.25798270
5ribosomal small subunit assembly (GO:0000028)7.78498116
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)7.35368039
7cotranslational protein targeting to membrane (GO:0006613)7.27788831
8translational elongation (GO:0006414)7.25214786
9protein targeting to ER (GO:0045047)7.23005326
10establishment of protein localization to endoplasmic reticulum (GO:0072599)6.95071562
11protein localization to endoplasmic reticulum (GO:0070972)6.75822984
12cellular protein complex disassembly (GO:0043624)6.60576618
13viral life cycle (GO:0019058)6.53810641
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)6.44013634
15energy coupled proton transport, down electrochemical gradient (GO:0015985)5.80122673
16ATP synthesis coupled proton transport (GO:0015986)5.80122673
17protein complex disassembly (GO:0043241)5.58621258
18translational initiation (GO:0006413)5.51675436
19mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.43146381
20macromolecular complex disassembly (GO:0032984)5.33916637
21protein targeting to membrane (GO:0006612)5.02520208
22ribosomal large subunit biogenesis (GO:0042273)4.90666950
23nuclear-transcribed mRNA catabolic process (GO:0000956)4.56321285
24protein neddylation (GO:0045116)4.50182500
25behavioral response to nicotine (GO:0035095)4.38718644
26translation (GO:0006412)4.37222938
27mRNA catabolic process (GO:0006402)4.31467179
28NADH dehydrogenase complex assembly (GO:0010257)4.29056625
29mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.29056625
30mitochondrial respiratory chain complex I assembly (GO:0032981)4.29056625
31mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.19948076
32substrate-independent telencephalic tangential migration (GO:0021826)4.13852402
33substrate-independent telencephalic tangential interneuron migration (GO:0021843)4.13852402
34chaperone-mediated protein transport (GO:0072321)4.11181296
35respiratory electron transport chain (GO:0022904)4.02020422
36electron transport chain (GO:0022900)3.99465084
37protein complex biogenesis (GO:0070271)3.92051995
38RNA catabolic process (GO:0006401)3.91887799
39ribonucleoprotein complex biogenesis (GO:0022613)3.81583739
40RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.74459455
41tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.74459455
42nonmotile primary cilium assembly (GO:0035058)3.69972773
43cellular component biogenesis (GO:0044085)3.64241129
44pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.60841715
45GTP biosynthetic process (GO:0006183)3.49860299
46mitochondrial respiratory chain complex assembly (GO:0033108)3.47390319
47establishment of protein localization to membrane (GO:0090150)3.37281416
48purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.30269734
49cell proliferation in forebrain (GO:0021846)3.25149087
50purine nucleoside triphosphate biosynthetic process (GO:0009145)3.24163096
51ATP biosynthetic process (GO:0006754)3.24083240
52protein targeting (GO:0006605)3.19302314
53epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.16982591
54establishment of protein localization to mitochondrial membrane (GO:0090151)3.13802528
55hydrogen ion transmembrane transport (GO:1902600)3.07289485
56nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.06656868
57positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.06075865
58regulation of cilium movement (GO:0003352)3.04995810
59exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.98610567
60establishment of protein localization to organelle (GO:0072594)2.97111187
61UTP biosynthetic process (GO:0006228)2.96172132
62pyrimidine nucleotide catabolic process (GO:0006244)2.95680021
63tongue development (GO:0043586)2.94913614
64negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.89303013
65spinal cord association neuron differentiation (GO:0021527)2.88159564
66preassembly of GPI anchor in ER membrane (GO:0016254)2.87292281
67cardiovascular system development (GO:0072358)2.84992779
68piRNA metabolic process (GO:0034587)2.82474031
69rRNA processing (GO:0006364)2.82293694
70gonadal mesoderm development (GO:0007506)2.81818801
71rRNA metabolic process (GO:0016072)2.81479386
72proton transport (GO:0015992)2.81434621
73ribonucleoside triphosphate biosynthetic process (GO:0009201)2.81326349
74kynurenine metabolic process (GO:0070189)2.80467345
75UTP metabolic process (GO:0046051)2.80141620
76organelle disassembly (GO:1903008)2.77575508
77aldehyde catabolic process (GO:0046185)2.77249291
78regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.77237569
79hydrogen transport (GO:0006818)2.74541800
80pattern specification involved in kidney development (GO:0061004)2.70452548
81protein localization to membrane (GO:0072657)2.70360849
82somite development (GO:0061053)2.69701302
83segment specification (GO:0007379)2.68977344
84detection of light stimulus involved in sensory perception (GO:0050962)2.66792979
85detection of light stimulus involved in visual perception (GO:0050908)2.66792979
86neuron fate determination (GO:0048664)2.66115518
87rRNA catabolic process (GO:0016075)2.65481160
88DNA methylation involved in gamete generation (GO:0043046)2.63439628
89synaptic transmission, cholinergic (GO:0007271)2.61969572
90base-excision repair, AP site formation (GO:0006285)2.61768048
91intraciliary transport (GO:0042073)2.60207049
92water-soluble vitamin biosynthetic process (GO:0042364)2.59046641
93RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)2.57398401
94regulation of microtubule-based movement (GO:0060632)2.56993182
95microtubule severing (GO:0051013)2.56730486
96regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.56099051
97negative regulation of synaptic transmission, GABAergic (GO:0032229)2.55164115
98viral protein processing (GO:0019082)2.55097543
99pyrimidine nucleobase catabolic process (GO:0006208)2.53852803
100ncRNA 3-end processing (GO:0043628)2.50586919

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human7.74755470
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.44918521
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.27812490
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.25043775
5EST1_17652178_ChIP-ChIP_JURKAT_Human2.57840934
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.54666581
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.36104302
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.32187055
9VDR_22108803_ChIP-Seq_LS180_Human2.30344071
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.15922516
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.05528740
12ZNF274_21170338_ChIP-Seq_K562_Hela1.99858565
13JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.96010045
14MYC_18555785_ChIP-Seq_MESCs_Mouse1.93683399
15EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.78451203
16JARID2_20064375_ChIP-Seq_MESCs_Mouse1.76657375
17IRF1_19129219_ChIP-ChIP_H3396_Human1.76100382
18CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.73955682
19BMI1_23680149_ChIP-Seq_NPCS_Mouse1.65551468
20TTF2_22483619_ChIP-Seq_HELA_Human1.65006115
21CBX2_27304074_Chip-Seq_ESCs_Mouse1.64558967
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.63730599
23MYC_18940864_ChIP-ChIP_HL60_Human1.62880616
24EZH2_27294783_Chip-Seq_ESCs_Mouse1.54850867
25ETV2_25802403_ChIP-Seq_MESCs_Mouse1.54013528
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.53766187
27REST_21632747_ChIP-Seq_MESCs_Mouse1.53549301
28CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.50490203
29TP53_22573176_ChIP-Seq_HFKS_Human1.48851690
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.48780856
31ELK1_19687146_ChIP-ChIP_HELA_Human1.47815631
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.46883470
33VDR_23849224_ChIP-Seq_CD4+_Human1.46141423
34MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.41658974
35FOXP3_21729870_ChIP-Seq_TREG_Human1.37868489
36RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.37216701
37RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36178598
38GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35792520
39MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.34656583
40TDRD3_21172665_ChIP-Seq_MCF-7_Human1.32991233
41SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.26114475
42MYC_19079543_ChIP-ChIP_MESCs_Mouse1.25579537
43TAF2_19829295_ChIP-Seq_ESCs_Human1.25278263
44AUTS2_25519132_ChIP-Seq_293T-REX_Human1.24607403
45RNF2_27304074_Chip-Seq_ESCs_Mouse1.24171988
46GATA1_26923725_Chip-Seq_HPCs_Mouse1.24121484
47CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.23952633
48GATA3_21878914_ChIP-Seq_MCF-7_Human1.22609413
49NANOG_20526341_ChIP-Seq_ESCs_Human1.21272679
50CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.21239428
51EWS_26573619_Chip-Seq_HEK293_Human1.17640637
52EED_16625203_ChIP-ChIP_MESCs_Mouse1.16161478
53FOXH1_21741376_ChIP-Seq_ESCs_Human1.14804025
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.13085379
55EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.10848362
56ELK1_22589737_ChIP-Seq_MCF10A_Human1.10547389
57FUS_26573619_Chip-Seq_HEK293_Human1.09922842
58JARID2_20075857_ChIP-Seq_MESCs_Mouse1.08863514
59XRN2_22483619_ChIP-Seq_HELA_Human1.08605553
60REST_18959480_ChIP-ChIP_MESCs_Mouse1.08068811
61RNF2_27304074_Chip-Seq_NSC_Mouse1.07793641
62CTBP1_25329375_ChIP-Seq_LNCAP_Human1.06904361
63MYC_18358816_ChIP-ChIP_MESCs_Mouse1.06903445
64SRY_22984422_ChIP-ChIP_TESTIS_Rat1.06603780
65SRF_21415370_ChIP-Seq_HL-1_Mouse1.06544375
66RNF2_18974828_ChIP-Seq_MESCs_Mouse1.06226353
67EZH2_18974828_ChIP-Seq_MESCs_Mouse1.06226353
68ERA_21632823_ChIP-Seq_H3396_Human1.05052927
69GBX2_23144817_ChIP-Seq_PC3_Human1.04747580
70KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.04185465
71POU5F1_16153702_ChIP-ChIP_HESCs_Human1.04175252
72IKZF1_21737484_ChIP-ChIP_HCT116_Human1.03708404
73MYC_19829295_ChIP-Seq_ESCs_Human1.03432176
74EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.02887770
75FOXA1_25329375_ChIP-Seq_VCAP_Human1.02256084
76FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02256084
77FOXH1_21741376_ChIP-Seq_EPCs_Human1.02051620
78GABP_19822575_ChIP-Seq_HepG2_Human1.01405606
79CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.00944173
80CTCF_27219007_Chip-Seq_Bcells_Human0.99472360
81SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.99203269
82CHD1_19587682_ChIP-ChIP_MESCs_Mouse0.98650992
83FLI1_27457419_Chip-Seq_LIVER_Mouse0.97385483
84POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.96092478
85FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95908052
86SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.95475444
87CTCF_20526341_ChIP-Seq_ESCs_Human0.92914335
88RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.92517627
89TP63_19390658_ChIP-ChIP_HaCaT_Human0.91864181
90YY1_21170310_ChIP-Seq_MESCs_Mouse0.91658433
91NCOR_22424771_ChIP-Seq_293T_Human0.90138097
92AR_20517297_ChIP-Seq_VCAP_Human0.90082152
93BCL6_27268052_Chip-Seq_Bcells_Human0.88721001
94SA1_27219007_Chip-Seq_Bcells_Human0.88189009
95HOXB7_26014856_ChIP-Seq_BT474_Human0.87800659
96PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.87798876
97GATA6_21074721_ChIP-Seq_CACO-2_Human0.87763887
98THAP11_20581084_ChIP-Seq_MESCs_Mouse0.87111149
99STAT1_20625510_ChIP-Seq_HELA_Human0.86683517
100GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.86406590

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.64419986
2MP0003787_abnormal_imprinting3.96719642
3MP0008877_abnormal_DNA_methylation3.57224331
4MP0006292_abnormal_olfactory_placode3.50624012
5MP0003878_abnormal_ear_physiology2.72930042
6MP0005377_hearing/vestibular/ear_phenot2.72930042
7MP0004142_abnormal_muscle_tone2.61186883
8MP0003646_muscle_fatigue2.55535628
9MP0008789_abnormal_olfactory_epithelium2.40487669
10MP0005394_taste/olfaction_phenotype2.08082261
11MP0005499_abnormal_olfactory_system2.08082261
12MP0003121_genomic_imprinting1.95194566
13MP0001293_anophthalmia1.85560244
14MP0001968_abnormal_touch/_nociception1.76022830
15MP0001440_abnormal_grooming_behavior1.75412809
16MP0001485_abnormal_pinna_reflex1.72729784
17MP0003122_maternal_imprinting1.71033955
18MP0006072_abnormal_retinal_apoptosis1.67158875
19MP0002272_abnormal_nervous_system1.66192420
20MP0002837_dystrophic_cardiac_calcinosis1.62634924
21MP0001529_abnormal_vocalization1.57436319
22MP0005551_abnormal_eye_electrophysiolog1.54113267
23MP0001984_abnormal_olfaction1.54083367
24MP0004885_abnormal_endolymph1.53895595
25MP0002736_abnormal_nociception_after1.53414051
26MP0001986_abnormal_taste_sensitivity1.52720475
27MP0005646_abnormal_pituitary_gland1.52287237
28MP0000566_synostosis1.49303719
29MP0002653_abnormal_ependyma_morphology1.45851526
30MP0004742_abnormal_vestibular_system1.45546751
31MP0002163_abnormal_gland_morphology1.44873885
32MP0001348_abnormal_lacrimal_gland1.43239895
33MP0004145_abnormal_muscle_electrophysio1.42706102
34MP0003123_paternal_imprinting1.41335016
35MP0002102_abnormal_ear_morphology1.41160006
36MP0000049_abnormal_middle_ear1.40034700
37MP0005671_abnormal_response_to1.38018621
38MP0006276_abnormal_autonomic_nervous1.36762963
39MP0009046_muscle_twitch1.36262831
40MP0004147_increased_porphyrin_level1.32188109
41MP0008872_abnormal_physiological_respon1.26423013
42MP0008875_abnormal_xenobiotic_pharmacok1.26151105
43MP0003879_abnormal_hair_cell1.25934380
44MP0001970_abnormal_pain_threshold1.22985336
45MP0002822_catalepsy1.21307867
46MP0003186_abnormal_redox_activity1.20867227
47MP0009745_abnormal_behavioral_response1.15774460
48MP0005423_abnormal_somatic_nervous1.14379914
49MP0003136_yellow_coat_color1.13463871
50MP0002138_abnormal_hepatobiliary_system1.10888609
51MP0005195_abnormal_posterior_eye1.10768425
52MP0001905_abnormal_dopamine_level1.09797142
53MP0002557_abnormal_social/conspecific_i1.09479707
54MP0001486_abnormal_startle_reflex1.09398988
55MP0000778_abnormal_nervous_system1.08286730
56MP0000372_irregular_coat_pigmentation1.08217367
57MP0009764_decreased_sensitivity_to1.07554831
58MP0003806_abnormal_nucleotide_metabolis1.07493371
59MP0003567_abnormal_fetal_cardiomyocyte1.06884714
60MP0005645_abnormal_hypothalamus_physiol1.06875448
61MP0004133_heterotaxia1.05467126
62MP0002572_abnormal_emotion/affect_behav1.04585281
63MP0005253_abnormal_eye_physiology1.03796215
64MP0005389_reproductive_system_phenotype1.02982395
65MP0003635_abnormal_synaptic_transmissio1.02058190
66MP0002095_abnormal_skin_pigmentation1.01180588
67MP0002733_abnormal_thermal_nociception0.99387252
68MP0010030_abnormal_orbit_morphology0.99163811
69MP0002184_abnormal_innervation0.98046953
70MP0002234_abnormal_pharynx_morphology0.96121968
71MP0002752_abnormal_somatic_nervous0.94492933
72MP0002938_white_spotting0.93922536
73MP0003880_abnormal_central_pattern0.92290039
74MP0002160_abnormal_reproductive_system0.90441885
75MP0000026_abnormal_inner_ear0.90004737
76MP0005379_endocrine/exocrine_gland_phen0.89902508
77MP0002063_abnormal_learning/memory/cond0.87471963
78MP0001919_abnormal_reproductive_system0.86820489
79MP0002734_abnormal_mechanical_nocicepti0.86664144
80MP0001502_abnormal_circadian_rhythm0.85959996
81MP0000631_abnormal_neuroendocrine_gland0.85941299
82MP0008775_abnormal_heart_ventricle0.83709358
83MP0002064_seizures0.82383764
84MP0003011_delayed_dark_adaptation0.80626775
85MP0005174_abnormal_tail_pigmentation0.80219741
86MP0002067_abnormal_sensory_capabilities0.80142028
87MP0005083_abnormal_biliary_tract0.80026818
88MP0003718_maternal_effect0.78293109
89MP0001835_abnormal_antigen_presentation0.76491269
90MP0002735_abnormal_chemical_nociception0.75741353
91MP0002233_abnormal_nose_morphology0.72160436
92MP0001324_abnormal_eye_pigmentation0.70619039
93MP0001963_abnormal_hearing_physiology0.70006396
94MP0000230_abnormal_systemic_arterial0.69621082
95MP0005075_abnormal_melanosome_morpholog0.69271522
96MP0008995_early_reproductive_senescence0.68206027
97MP0000955_abnormal_spinal_cord0.67857038
98MP0002210_abnormal_sex_determination0.67217945
99MP0005386_behavior/neurological_phenoty0.66498552
100MP0004924_abnormal_behavior0.66498552

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)6.78868376
2Abnormality of cells of the erythroid lineage (HP:0012130)5.02321149
3Acute necrotizing encephalopathy (HP:0006965)4.88750305
4Abnormal hemoglobin (HP:0011902)4.70619006
5Acute encephalopathy (HP:0006846)4.64821615
6Abnormal mitochondria in muscle tissue (HP:0008316)4.31449152
7Abnormality of midbrain morphology (HP:0002418)4.12220122
8Molar tooth sign on MRI (HP:0002419)4.12220122
9Progressive macrocephaly (HP:0004481)3.95418237
10Macrocytic anemia (HP:0001972)3.91855989
11Mitochondrial inheritance (HP:0001427)3.87158230
12Pallor (HP:0000980)3.84730900
13Pancreatic fibrosis (HP:0100732)3.77396384
14Abnormal number of erythroid precursors (HP:0012131)3.55220757
15Increased CSF lactate (HP:0002490)3.37077913
16Hepatocellular necrosis (HP:0001404)3.29278787
17Hyperglycinemia (HP:0002154)3.22686004
18Cerebral edema (HP:0002181)3.17639648
19Absent rod-and cone-mediated responses on ERG (HP:0007688)3.16058622
20Pancreatic cysts (HP:0001737)3.07928576
21Septo-optic dysplasia (HP:0100842)3.04064672
22Type II lissencephaly (HP:0007260)3.00639830
23Aplasia/Hypoplasia of the spleen (HP:0010451)2.99268171
24Nephronophthisis (HP:0000090)2.98825496
25Hepatic necrosis (HP:0002605)2.93735083
26Asplenia (HP:0001746)2.77634457
27Medial flaring of the eyebrow (HP:0010747)2.74489716
28Optic disc pallor (HP:0000543)2.67561683
29Stenosis of the external auditory canal (HP:0000402)2.66068943
30Abnormal rod and cone electroretinograms (HP:0008323)2.65836946
31Rib fusion (HP:0000902)2.58044482
32Leukodystrophy (HP:0002415)2.52739287
33Cystic liver disease (HP:0006706)2.51468176
34Myokymia (HP:0002411)2.50709270
35Increased hepatocellular lipid droplets (HP:0006565)2.44597338
36True hermaphroditism (HP:0010459)2.44097876
37Abolished electroretinogram (ERG) (HP:0000550)2.43334178
38Absent thumb (HP:0009777)2.42428419
39Abnormality of the renal medulla (HP:0100957)2.38180201
40Congenital, generalized hypertrichosis (HP:0004540)2.38081542
41Lipid accumulation in hepatocytes (HP:0006561)2.36320346
42Aplasia/Hypoplasia of the sacrum (HP:0008517)2.30312086
43Hyperglycinuria (HP:0003108)2.29011332
44Anencephaly (HP:0002323)2.26244846
45Postaxial foot polydactyly (HP:0001830)2.25456521
46Abnormality of reticulocytes (HP:0004312)2.23483988
47Sclerocornea (HP:0000647)2.21115693
48Renal Fanconi syndrome (HP:0001994)2.20672685
49Cerebellar dysplasia (HP:0007033)2.18526855
50Supernumerary spleens (HP:0009799)2.11695195
51Increased intramyocellular lipid droplets (HP:0012240)2.11217328
52Pendular nystagmus (HP:0012043)2.11138702
53Anophthalmia (HP:0000528)2.11135171
54Gait imbalance (HP:0002141)2.09265586
55Lactic acidosis (HP:0003128)2.08634932
56Congenital stationary night blindness (HP:0007642)2.07719035
57Tachypnea (HP:0002789)2.06859741
58Degeneration of the lateral corticospinal tracts (HP:0002314)2.05429355
59Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.05429355
603-Methylglutaconic aciduria (HP:0003535)2.05329910
61Congenital hepatic fibrosis (HP:0002612)2.00702841
62Polydipsia (HP:0001959)1.97627363
63Abnormal drinking behavior (HP:0030082)1.97627363
64Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.97053720
65Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.96229270
66Hypoplasia of the ulna (HP:0003022)1.96158934
67Hyperthyroidism (HP:0000836)1.95936436
68Hypoplasia of the radius (HP:0002984)1.94059267
69Respiratory failure (HP:0002878)1.93396907
70Abnormality of the renal cortex (HP:0011035)1.93192788
71Congenital primary aphakia (HP:0007707)1.92396634
72Nephrogenic diabetes insipidus (HP:0009806)1.91012287
73Lethargy (HP:0001254)1.90740280
74Increased serum lactate (HP:0002151)1.90615365
75Depressed nasal ridge (HP:0000457)1.88320398
76Polyphagia (HP:0002591)1.87623898
77Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.87437367
78Decreased activity of mitochondrial respiratory chain (HP:0008972)1.87437367
79Symphalangism affecting the phalanges of the hand (HP:0009773)1.85727693
80Abnormality of the heme biosynthetic pathway (HP:0010472)1.85615380
81Abnormality of serine family amino acid metabolism (HP:0010894)1.82390395
82Abnormality of glycine metabolism (HP:0010895)1.82390395
83Agitation (HP:0000713)1.81972020
84Abnormality of the corticospinal tract (HP:0002492)1.80017447
85Renal cortical cysts (HP:0000803)1.78628402
86Increased muscle lipid content (HP:0009058)1.78266883
87Aplasia/Hypoplasia of the ulna (HP:0006495)1.77225119
88Growth hormone deficiency (HP:0000824)1.76642317
89Bifid tongue (HP:0010297)1.75859335
90Abnormal respiratory motile cilium physiology (HP:0012261)1.75329646
91Pachygyria (HP:0001302)1.74582040
92Lissencephaly (HP:0001339)1.73808483
93Postaxial hand polydactyly (HP:0001162)1.73336660
94Abnormality of DNA repair (HP:0003254)1.72354377
95Absent septum pellucidum (HP:0001331)1.72013582
96Abnormal ciliary motility (HP:0012262)1.71731669
97Abnormal biliary tract physiology (HP:0012439)1.70682863
98Bile duct proliferation (HP:0001408)1.70682863
99Horseshoe kidney (HP:0000085)1.69661068
100Forearm undergrowth (HP:0009821)1.69466085

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK44.28760893
2STK162.78977042
3PINK12.72714221
4BCKDK2.60744356
5GRK12.53252759
6ADRBK22.51645098
7DYRK22.45181884
8STK392.43511649
9TIE12.26227546
10WNK12.26042611
11CDK192.12680443
12TLK12.06305005
13TAOK31.95885119
14LRRK21.90796037
15FRK1.70112270
16TXK1.63343745
17MAP3K111.51987863
18TYRO31.49235922
19OXSR11.46781527
20MAP4K21.41478194
21BMPR1B1.38294173
22ZAK1.36220239
23EPHB21.33516117
24PDK21.31046991
25TEC1.28980142
26PAK31.23057601
27PRKCG1.20072801
28BRAF1.19841671
29NUAK11.19021402
30PHKG21.17537336
31PHKG11.17537336
32RPS6KA61.15066359
33DAPK31.12708129
34ACVR1B1.06570109
35PIK3CA1.04205628
36EPHA41.04126664
37WNK31.03194758
38PLK41.02210843
39RPS6KL10.98734097
40RPS6KC10.98734097
41IKBKB0.94412947
42BMPR20.94266700
43DAPK20.94101472
44ADRBK10.92932535
45PRKCQ0.91506522
46MINK10.91437332
47PIM20.90414950
48NEK10.88546213
49NTRK20.88269880
50DMPK0.84835753
51MAP2K70.84697583
52CAMK10.84611495
53INSRR0.84183572
54ABL20.84162834
55CAMKK20.83663138
56RPS6KA50.82413128
57MAP3K40.79299933
58CSNK2A20.79151799
59TGFBR10.78894487
60NME20.78363068
61MARK10.77331256
62PRKACA0.74538273
63CSNK1G20.74377244
64BTK0.72510297
65CDC70.72124819
66NME10.71198930
67MAP4K10.70511717
68RPS6KA20.69696364
69PRKCZ0.68370240
70MAPK130.66612862
71CASK0.65192143
72PRKCI0.64816224
73MAP2K20.62313308
74MKNK20.62248938
75ITK0.61421640
76CSNK1E0.60716569
77CDK80.59049414
78ARAF0.57799779
79NEK20.57042705
80OBSCN0.56565925
81SIK20.55569897
82RPS6KA10.54490206
83MAPK150.54475655
84CSNK1G10.53407892
85AURKA0.52763628
86PAK60.51227665
87STK110.50797223
88PRKCH0.49702523
89PNCK0.48030858
90CSNK2A10.47448385
91CSNK1G30.46682375
92SGK10.46189916
93PRKCE0.46069288
94CAMK2A0.44919633
95CHEK20.44758365
96KIT0.44353556
97AURKB0.43588730
98GRK70.43222678
99DAPK10.43183338
100MAPKAPK30.42224956

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030107.09057919
2Oxidative phosphorylation_Homo sapiens_hsa001904.31998602
3Parkinsons disease_Homo sapiens_hsa050123.49854004
4Cardiac muscle contraction_Homo sapiens_hsa042602.92971597
5Asthma_Homo sapiens_hsa053102.81449681
6Huntingtons disease_Homo sapiens_hsa050162.53431806
7Alzheimers disease_Homo sapiens_hsa050102.50611685
8Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.49774042
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.19952445
10Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.19010361
11Linoleic acid metabolism_Homo sapiens_hsa005912.12942973
12alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.11657797
13Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.05574373
14Allograft rejection_Homo sapiens_hsa053301.97927686
15Autoimmune thyroid disease_Homo sapiens_hsa053201.86500454
16RNA polymerase_Homo sapiens_hsa030201.82804335
17RNA degradation_Homo sapiens_hsa030181.74476777
18Proteasome_Homo sapiens_hsa030501.69923884
19Protein export_Homo sapiens_hsa030601.67572768
20Graft-versus-host disease_Homo sapiens_hsa053321.61874570
21Nicotine addiction_Homo sapiens_hsa050331.53484166
22Phototransduction_Homo sapiens_hsa047441.51947375
23Type I diabetes mellitus_Homo sapiens_hsa049401.43061138
24Sulfur relay system_Homo sapiens_hsa041221.32580826
25Homologous recombination_Homo sapiens_hsa034401.26309879
26Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.21565814
27Ether lipid metabolism_Homo sapiens_hsa005651.18273776
28Arachidonic acid metabolism_Homo sapiens_hsa005901.11518724
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.10920781
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.06568950
31Basal transcription factors_Homo sapiens_hsa030221.01628447
32One carbon pool by folate_Homo sapiens_hsa006700.99842140
33Fat digestion and absorption_Homo sapiens_hsa049750.98391874
34Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.97579057
35Propanoate metabolism_Homo sapiens_hsa006400.93318198
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.88701146
37Rheumatoid arthritis_Homo sapiens_hsa053230.82436821
38Nitrogen metabolism_Homo sapiens_hsa009100.82087608
39Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.80974749
40Peroxisome_Homo sapiens_hsa041460.78788630
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.78295008
42Chemical carcinogenesis_Homo sapiens_hsa052040.76398428
43Tryptophan metabolism_Homo sapiens_hsa003800.75614095
44Pyrimidine metabolism_Homo sapiens_hsa002400.75066510
45Fanconi anemia pathway_Homo sapiens_hsa034600.74499050
46Olfactory transduction_Homo sapiens_hsa047400.74097839
47Nucleotide excision repair_Homo sapiens_hsa034200.72670020
48Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.72325867
49Morphine addiction_Homo sapiens_hsa050320.72115677
50Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.71489480
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70174674
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.68087978
53Retinol metabolism_Homo sapiens_hsa008300.63302136
54Metabolic pathways_Homo sapiens_hsa011000.61730428
55Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.60199460
56Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.60160552
57Collecting duct acid secretion_Homo sapiens_hsa049660.58797887
58Taste transduction_Homo sapiens_hsa047420.57195983
59Steroid hormone biosynthesis_Homo sapiens_hsa001400.56925082
60Fatty acid biosynthesis_Homo sapiens_hsa000610.54949579
61Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.53551520
62Caffeine metabolism_Homo sapiens_hsa002320.51376926
63RNA transport_Homo sapiens_hsa030130.51351970
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.49991327
65Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.48921928
66Viral myocarditis_Homo sapiens_hsa054160.48769624
67Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.48479472
68Butanoate metabolism_Homo sapiens_hsa006500.47985807
69Ovarian steroidogenesis_Homo sapiens_hsa049130.46626363
70Fatty acid degradation_Homo sapiens_hsa000710.46363619
71Systemic lupus erythematosus_Homo sapiens_hsa053220.46029094
72GABAergic synapse_Homo sapiens_hsa047270.45940037
73Purine metabolism_Homo sapiens_hsa002300.44868867
74Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44222885
75Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.42737298
76Spliceosome_Homo sapiens_hsa030400.41647088
77Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40147389
78beta-Alanine metabolism_Homo sapiens_hsa004100.40129085
79Folate biosynthesis_Homo sapiens_hsa007900.39562340
80Steroid biosynthesis_Homo sapiens_hsa001000.37399775
81Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.36829902
82Mineral absorption_Homo sapiens_hsa049780.35517625
83Sulfur metabolism_Homo sapiens_hsa009200.34974028
84Insulin secretion_Homo sapiens_hsa049110.33560304
85Base excision repair_Homo sapiens_hsa034100.33062916
86Basal cell carcinoma_Homo sapiens_hsa052170.32520986
87Primary immunodeficiency_Homo sapiens_hsa053400.32238831
88Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.31323723
89Glutamatergic synapse_Homo sapiens_hsa047240.31055894
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29223317
91Antigen processing and presentation_Homo sapiens_hsa046120.28109063
92Dorso-ventral axis formation_Homo sapiens_hsa043200.26231637
93Hedgehog signaling pathway_Homo sapiens_hsa043400.25339780
94Tyrosine metabolism_Homo sapiens_hsa003500.23334814
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.22066260
96Cyanoamino acid metabolism_Homo sapiens_hsa004600.21235456
97Hematopoietic cell lineage_Homo sapiens_hsa046400.19091330
98Staphylococcus aureus infection_Homo sapiens_hsa051500.19017378
99Maturity onset diabetes of the young_Homo sapiens_hsa049500.17768573
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.15749808

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