RPS26P11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cytidine metabolic process (GO:0046087)8.89765220
2cytidine catabolic process (GO:0006216)8.89765220
3cytidine deamination (GO:0009972)8.89765220
4regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450918.85753769
5pyrimidine ribonucleoside catabolic process (GO:0046133)8.00877974
6Arp2/3 complex-mediated actin nucleation (GO:0034314)4.23780784
7pyrimidine nucleoside catabolic process (GO:0046135)4.03937488
8mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.93774678
9ATP synthesis coupled proton transport (GO:0015986)3.91771343
10energy coupled proton transport, down electrochemical gradient (GO:0015985)3.91771343
11actin nucleation (GO:0045010)3.86466265
12positive thymic T cell selection (GO:0045059)3.72087987
13negative T cell selection (GO:0043383)3.68581308
14positive T cell selection (GO:0043368)3.68214538
15behavioral response to nicotine (GO:0035095)3.65962303
16positive regulation of prostaglandin secretion (GO:0032308)3.56474930
17proteasome assembly (GO:0043248)3.55381740
18protein neddylation (GO:0045116)3.53031395
19ribosomal small subunit assembly (GO:0000028)3.49656381
20positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.46893662
21positive regulation of defense response to virus by host (GO:0002230)3.40633347
22positive regulation of natural killer cell mediated immunity (GO:0002717)3.34662698
23positive regulation of uterine smooth muscle contraction (GO:0070474)3.34038331
24negative regulation of T cell apoptotic process (GO:0070233)3.33505631
25regulation of regulatory T cell differentiation (GO:0045589)3.29692921
26negative regulation of viral genome replication (GO:0045071)3.27839352
27sequestering of actin monomers (GO:0042989)3.24863592
28T cell migration (GO:0072678)3.24318520
29positive regulation of interleukin-8 secretion (GO:2000484)3.24228504
30mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.23019569
31positive regulation of fatty acid transport (GO:2000193)3.20872722
32tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.20192964
33RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.20192964
34negative regulation of mast cell activation (GO:0033004)3.19292116
35cellular response to interleukin-15 (GO:0071350)3.18817960
36positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.18778498
37positive regulation of tolerance induction (GO:0002645)3.14560558
38regulation of T cell receptor signaling pathway (GO:0050856)3.14530479
39negative regulation by host of viral transcription (GO:0043922)3.14063752
40DNA demethylation (GO:0080111)3.13137105
41respiratory electron transport chain (GO:0022904)3.10535003
42electron transport chain (GO:0022900)3.09325435
43maturation of SSU-rRNA (GO:0030490)3.09104648
44negative thymic T cell selection (GO:0045060)3.07526247
45regulation of B cell receptor signaling pathway (GO:0050855)3.06420740
46positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.06371731
47positive regulation of calcium-mediated signaling (GO:0050850)3.05463979
48positive regulation of protein homodimerization activity (GO:0090073)3.05081136
49negative regulation of lymphocyte apoptotic process (GO:0070229)2.99155809
50protein-cofactor linkage (GO:0018065)2.97766083
51regulation of chronic inflammatory response (GO:0002676)2.96017752
52platelet dense granule organization (GO:0060155)2.95421120
53negative regulation of telomere maintenance (GO:0032205)2.94587711
54positive regulation of cell killing (GO:0031343)2.90144392
55regulation of activation of Janus kinase activity (GO:0010533)2.88740263
56regulation of isotype switching to IgG isotypes (GO:0048302)2.85988242
57regulation of leukocyte mediated cytotoxicity (GO:0001910)2.85718615
58thymic T cell selection (GO:0045061)2.84055826
59regulation of cellular amino acid metabolic process (GO:0006521)2.81810551
60establishment of protein localization to mitochondrial membrane (GO:0090151)2.81650238
61regulation of uterine smooth muscle contraction (GO:0070472)2.81568564
62positive regulation of icosanoid secretion (GO:0032305)2.80512371
63regulation of prostaglandin secretion (GO:0032306)2.80207486
64chaperone-mediated protein transport (GO:0072321)2.79840533
65regulation of natural killer cell mediated immunity (GO:0002715)2.79555361
66regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.79555361
67cytolysis (GO:0019835)2.77838303
68response to interferon-beta (GO:0035456)2.77645516
69pyrimidine-containing compound catabolic process (GO:0072529)2.77592592
70negative regulation of B cell apoptotic process (GO:0002903)2.76481355
71positive regulation of T cell mediated cytotoxicity (GO:0001916)2.76283283
72regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.75631485
73regulation of T cell tolerance induction (GO:0002664)2.74301846
74rRNA modification (GO:0000154)2.72301970
75DNA dealkylation (GO:0035510)2.71699766
76DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.71531101
77T cell receptor signaling pathway (GO:0050852)2.71265332
78iron-sulfur cluster assembly (GO:0016226)2.69206609
79metallo-sulfur cluster assembly (GO:0031163)2.69206609
80negative regulation of nitric-oxide synthase activity (GO:0051001)2.66497131
81pyrimidine ribonucleoside metabolic process (GO:0046131)2.64932105
82negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.63642308
83positive regulation of T cell chemotaxis (GO:0010820)2.63177082
84regulation of T cell chemotaxis (GO:0010819)2.63177082
85regulation of cell killing (GO:0031341)2.62728462
86signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.61592052
87signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.61592052
88signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.61592052
89positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.61262609
90protein complex biogenesis (GO:0070271)2.60653963
91signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.59460955
92intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.59460955
93S-adenosylmethionine metabolic process (GO:0046500)2.57555410
94mast cell activation (GO:0045576)2.57242259
95mast cell degranulation (GO:0043303)2.57200343
96mast cell activation involved in immune response (GO:0002279)2.57200343
97sulfation (GO:0051923)2.57155036
98regulation of T cell mediated cytotoxicity (GO:0001914)2.55622744
99ubiquinone biosynthetic process (GO:0006744)2.53242451
100DNA deamination (GO:0045006)10.0050396

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human3.84473980
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.36526419
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.34993898
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.31581935
5ELF1_17652178_ChIP-ChIP_JURKAT_Human2.98145833
6IRF8_22096565_ChIP-ChIP_GC-B_Human2.91934558
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.86857287
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.72467964
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.63805292
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.61987801
11EST1_17652178_ChIP-ChIP_JURKAT_Human2.51428687
12HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.47607860
13VDR_22108803_ChIP-Seq_LS180_Human2.46176587
14ZNF274_21170338_ChIP-Seq_K562_Hela2.39913467
15VDR_23849224_ChIP-Seq_CD4+_Human2.39441326
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.35711535
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.19549169
18ETS1_20019798_ChIP-Seq_JURKAT_Human2.07847531
19FLI1_27457419_Chip-Seq_LIVER_Mouse2.06708556
20IRF8_21731497_ChIP-ChIP_J774_Mouse1.99048102
21LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.98219754
22E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.94293386
23SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.93810299
24EZH2_22144423_ChIP-Seq_EOC_Human1.91660810
25NOTCH1_21737748_ChIP-Seq_TLL_Human1.89706143
26SRF_21415370_ChIP-Seq_HL-1_Mouse1.87810461
27FOXP3_21729870_ChIP-Seq_TREG_Human1.80794512
28RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.69165257
29MYB_26560356_Chip-Seq_TH2_Human1.64338299
30YY1_21170310_ChIP-Seq_MESCs_Mouse1.63095341
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.62747163
32GATA3_26560356_Chip-Seq_TH2_Human1.62287284
33MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.61180039
34FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.54252779
35FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.52638739
36TP53_22573176_ChIP-Seq_HFKS_Human1.52247930
37IGF1R_20145208_ChIP-Seq_DFB_Human1.51543121
38NCOR_22424771_ChIP-Seq_293T_Human1.49948367
39CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.47632462
40ELK1_19687146_ChIP-ChIP_HELA_Human1.46162668
41SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.44658025
42EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.40611022
43PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.39470264
44EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.35483595
45MYC_18940864_ChIP-ChIP_HL60_Human1.35482822
46PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.33541320
47EWS_26573619_Chip-Seq_HEK293_Human1.29978586
48RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.28562718
49STAT4_19710469_ChIP-ChIP_TH1__Mouse1.28494548
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.27986371
51IRF1_19129219_ChIP-ChIP_H3396_Human1.26241863
52PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.25253334
53VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.21983205
54RUNX_20019798_ChIP-Seq_JUKART_Human1.21870719
55PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21507274
56NANOG_20526341_ChIP-Seq_ESCs_Human1.20387719
57GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19367253
58* GATA3_27048872_Chip-Seq_THYMUS_Human1.17839291
59TAF2_19829295_ChIP-Seq_ESCs_Human1.15426907
60MYC_19829295_ChIP-Seq_ESCs_Human1.14065861
61FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.12976786
62TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.12857635
63ERA_21632823_ChIP-Seq_H3396_Human1.11695323
64FOXA1_25329375_ChIP-Seq_VCAP_Human1.11372622
65FOXA1_27270436_Chip-Seq_PROSTATE_Human1.11372622
66AR_20517297_ChIP-Seq_VCAP_Human1.09728747
67SOX2_19829295_ChIP-Seq_ESCs_Human1.09034258
68NANOG_19829295_ChIP-Seq_ESCs_Human1.09034258
69CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.08072980
70SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.05371039
71GATA3_21878914_ChIP-Seq_MCF-7_Human1.04359973
72AUTS2_25519132_ChIP-Seq_293T-REX_Human1.04019194
73EGR1_23403033_ChIP-Seq_LIVER_Mouse1.02343715
74NFE2_27457419_Chip-Seq_LIVER_Mouse1.01413864
75CREB1_15753290_ChIP-ChIP_HEK293T_Human0.99980962
76FOXH1_21741376_ChIP-Seq_EPCs_Human0.98391850
77HOXB7_26014856_ChIP-Seq_BT474_Human0.98334019
78BMI1_23680149_ChIP-Seq_NPCS_Mouse0.97642653
79* BCL6_27268052_Chip-Seq_Bcells_Human0.96839139
80CBP_20019798_ChIP-Seq_JUKART_Human0.96746950
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.96746950
82HOXB4_20404135_ChIP-ChIP_EML_Mouse0.96102232
83GBX2_23144817_ChIP-Seq_PC3_Human0.94876158
84GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.94727227
85MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.94712824
86LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.94501425
87CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.94113372
88ER_23166858_ChIP-Seq_MCF-7_Human0.94095279
89CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.93334776
90FOXA1_21572438_ChIP-Seq_LNCaP_Human0.92363290
91FOXH1_21741376_ChIP-Seq_ESCs_Human0.90441820
92OCT4_20526341_ChIP-Seq_ESCs_Human0.90302729
93MYB_26560356_Chip-Seq_TH1_Human0.89838787
94GATA6_21074721_ChIP-Seq_CACO-2_Human0.89779852
95POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.89645904
96RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89005928
97YY1_22570637_ChIP-Seq_MALME-3M_Human0.87879142
98RBPJ_21746931_ChIP-Seq_IB4_Human0.87566156
99* CTCF_20526341_ChIP-Seq_ESCs_Human0.87133823
100CIITA_25753668_ChIP-Seq_RAJI_Human0.85743041

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to4.76158082
2MP0004147_increased_porphyrin_level3.22776282
3MP0001835_abnormal_antigen_presentation2.78067029
4MP0003646_muscle_fatigue2.77771407
5MP0003763_abnormal_thymus_physiology2.68057670
6MP0000685_abnormal_immune_system2.66348501
7MP0009785_altered_susceptibility_to2.57741997
8MP0002138_abnormal_hepatobiliary_system2.08977231
9MP0008877_abnormal_DNA_methylation2.04744616
10MP0001873_stomach_inflammation2.02304543
11MP0005000_abnormal_immune_tolerance1.97394736
12MP0003786_premature_aging1.95444909
13MP0001188_hyperpigmentation1.88390558
14MP0000569_abnormal_digit_pigmentation1.86636127
15MP0001800_abnormal_humoral_immune1.85031945
16MP0009333_abnormal_splenocyte_physiolog1.83249534
17MP0003866_abnormal_defecation1.81374541
18MP0002148_abnormal_hypersensitivity_rea1.79067420
19MP0001905_abnormal_dopamine_level1.79059710
20MP0002420_abnormal_adaptive_immunity1.75955827
21MP0006072_abnormal_retinal_apoptosis1.72981932
22MP0002876_abnormal_thyroid_physiology1.70433354
23MP0005075_abnormal_melanosome_morpholog1.70417493
24MP0008872_abnormal_physiological_respon1.70069149
25MP0002736_abnormal_nociception_after1.69317816
26MP0001819_abnormal_immune_cell1.68675271
27MP0006292_abnormal_olfactory_placode1.68523649
28MP0001661_extended_life_span1.68395442
29MP0002723_abnormal_immune_serum1.67270675
30MP0005551_abnormal_eye_electrophysiolog1.66636950
31MP0005025_abnormal_response_to1.61632714
32MP0009379_abnormal_foot_pigmentation1.61593138
33MP0002822_catalepsy1.60015404
34MP0001790_abnormal_immune_system1.58712665
35MP0005387_immune_system_phenotype1.58712665
36MP0001968_abnormal_touch/_nociception1.57580844
37MP0004885_abnormal_endolymph1.53952322
38MP0002166_altered_tumor_susceptibility1.53765499
39MP0002006_tumorigenesis1.52708233
40MP0005645_abnormal_hypothalamus_physiol1.50986225
41MP0004145_abnormal_muscle_electrophysio1.50701947
42MP0003195_calcinosis1.49285860
43MP0001501_abnormal_sleep_pattern1.49021024
44MP0000703_abnormal_thymus_morphology1.44627365
45MP0002234_abnormal_pharynx_morphology1.39847474
46MP0003806_abnormal_nucleotide_metabolis1.39391523
47MP0001919_abnormal_reproductive_system1.35753798
48MP0003880_abnormal_central_pattern1.35069468
49MP0000716_abnormal_immune_system1.34813647
50MP0002398_abnormal_bone_marrow1.34546361
51MP0006082_CNS_inflammation1.34473573
52MP0008995_early_reproductive_senescence1.33826534
53MP0008875_abnormal_xenobiotic_pharmacok1.29513515
54MP0002452_abnormal_antigen_presenting1.26909467
55MP0002277_abnormal_respiratory_mucosa1.26563063
56MP0005389_reproductive_system_phenotype1.25367476
57MP0001542_abnormal_bone_strength1.24819338
58MP0002735_abnormal_chemical_nociception1.24446285
59MP0002405_respiratory_system_inflammati1.23839469
60MP0004142_abnormal_muscle_tone1.22498497
61MP0009745_abnormal_behavioral_response1.21882954
62MP0009764_decreased_sensitivity_to1.20946921
63MP0002722_abnormal_immune_system1.19404798
64MP0000372_irregular_coat_pigmentation1.18990832
65MP0009046_muscle_twitch1.18925436
66MP0000689_abnormal_spleen_morphology1.17254320
67MP0006276_abnormal_autonomic_nervous1.15812916
68MP0005084_abnormal_gallbladder_morpholo1.15714872
69MP0002272_abnormal_nervous_system1.13933013
70MP0003011_delayed_dark_adaptation1.12320214
71MP0002095_abnormal_skin_pigmentation1.08297776
72MP0008007_abnormal_cellular_replicative1.04690856
73MP0002163_abnormal_gland_morphology1.04324328
74MP0001845_abnormal_inflammatory_respons1.03440045
75MP0010155_abnormal_intestine_physiology0.98290070
76MP0002837_dystrophic_cardiac_calcinosis0.97483250
77MP0005253_abnormal_eye_physiology0.97066369
78MP0002429_abnormal_blood_cell0.96888201
79MP0002102_abnormal_ear_morphology0.94474732
80MP0002733_abnormal_thermal_nociception0.93095260
81MP0001970_abnormal_pain_threshold0.85962317
82MP0001986_abnormal_taste_sensitivity0.85707462
83MP0004043_abnormal_pH_regulation0.82332776
84MP0003436_decreased_susceptibility_to0.80956102
85MP0002160_abnormal_reproductive_system0.76509944
86MP0008789_abnormal_olfactory_epithelium0.75493403
87MP0002419_abnormal_innate_immunity0.74684623
88MP0005174_abnormal_tail_pigmentation0.74404680
89MP0000613_abnormal_salivary_gland0.74210930
90MP0002693_abnormal_pancreas_physiology0.72869450
91MP0008469_abnormal_protein_level0.72308654
92MP0005423_abnormal_somatic_nervous0.72238618
93MP0005646_abnormal_pituitary_gland0.71249524
94MP0008873_increased_physiological_sensi0.70609515
95MP0006036_abnormal_mitochondrial_physio0.69642459
96MP0001663_abnormal_digestive_system0.65926992
97MP0003448_altered_tumor_morphology0.65524216
98MP0001529_abnormal_vocalization0.64577049
99MP0005360_urolithiasis0.64334512
100MP0005410_abnormal_fertilization0.63257633

Predicted human phenotypes

RankGene SetZ-score
1IgG deficiency (HP:0004315)4.24057217
2Severe combined immunodeficiency (HP:0004430)3.90121376
3Pancreatic cysts (HP:0001737)3.82578118
4Mitochondrial inheritance (HP:0001427)3.75234050
5Aplastic anemia (HP:0001915)3.71399110
6Pancreatic fibrosis (HP:0100732)3.66304111
7T lymphocytopenia (HP:0005403)3.60088140
8Abnormality of T cell number (HP:0011839)3.58225515
9Increased hepatocellular lipid droplets (HP:0006565)3.57421542
10Hepatocellular necrosis (HP:0001404)3.41601099
11Lipid accumulation in hepatocytes (HP:0006561)3.37460192
12Thyroiditis (HP:0100646)3.32683272
13Increased intramyocellular lipid droplets (HP:0012240)3.30665183
14Acute necrotizing encephalopathy (HP:0006965)3.29344243
15Increased CSF lactate (HP:0002490)3.28413247
16Renal Fanconi syndrome (HP:0001994)3.27292565
17Abnormality of eosinophils (HP:0001879)3.26507917
18Abnormality of midbrain morphology (HP:0002418)3.24241445
19Molar tooth sign on MRI (HP:0002419)3.24241445
20Increased IgM level (HP:0003496)3.16396915
21Hepatic necrosis (HP:0002605)3.13819498
22Abnormal mitochondria in muscle tissue (HP:0008316)3.10486439
23Congenital stationary night blindness (HP:0007642)3.06090428
24Autoimmune hemolytic anemia (HP:0001890)2.97895674
25Congenital, generalized hypertrichosis (HP:0004540)2.97113763
26Combined immunodeficiency (HP:0005387)2.96041969
27True hermaphroditism (HP:0010459)2.89315980
28Abnormality of B cell number (HP:0010975)2.87997520
29Hypoproteinemia (HP:0003075)2.87318206
30Abolished electroretinogram (ERG) (HP:0000550)2.82550157
31Increased muscle lipid content (HP:0009058)2.80736780
32Elevated erythrocyte sedimentation rate (HP:0003565)2.78390233
33Acute encephalopathy (HP:0006846)2.72422324
34Progressive macrocephaly (HP:0004481)2.68664263
35Eosinophilia (HP:0001880)2.65467476
36Decreased electroretinogram (ERG) amplitude (HP:0000654)2.60092356
37Abnormality of T cells (HP:0002843)2.58747936
383-Methylglutaconic aciduria (HP:0003535)2.57620654
39Abnormality of the prostate (HP:0008775)2.56959110
40Increased serum lactate (HP:0002151)2.54884581
41Type 2 muscle fiber atrophy (HP:0003554)2.45853678
42Abnormality of the renal cortex (HP:0011035)2.40726422
43B lymphocytopenia (HP:0010976)2.39759077
44Absent rod-and cone-mediated responses on ERG (HP:0007688)2.38653480
45Generalized aminoaciduria (HP:0002909)2.34163325
46Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.32153813
47Cerebral edema (HP:0002181)2.30331847
48Attenuation of retinal blood vessels (HP:0007843)2.27625686
49Pancytopenia (HP:0001876)2.25752229
50Optic disc pallor (HP:0000543)2.24293279
51Renal cortical cysts (HP:0000803)2.23481690
52Exertional dyspnea (HP:0002875)2.18614448
53Cystic liver disease (HP:0006706)2.18448570
54Abnormal rod and cone electroretinograms (HP:0008323)2.18116184
55Hypoplasia of the pons (HP:0012110)2.15569539
56Muscle fiber atrophy (HP:0100295)2.14634175
57Stomatitis (HP:0010280)2.12159536
58Polydipsia (HP:0001959)2.11512846
59Abnormal drinking behavior (HP:0030082)2.11512846
60Chronic mucocutaneous candidiasis (HP:0002728)2.10241979
61Recurrent cutaneous fungal infections (HP:0011370)2.10241979
62Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.08220929
63Decreased activity of mitochondrial respiratory chain (HP:0008972)2.08220929
64Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.07771467
65Lactic acidosis (HP:0003128)2.06813040
66Abnormality of alanine metabolism (HP:0010916)2.04974043
67Hyperalaninemia (HP:0003348)2.04974043
68Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.04974043
69Polyuria (HP:0000103)2.04672655
70Chronic hepatic failure (HP:0100626)2.03875296
71Prostate neoplasm (HP:0100787)2.01505637
72Type I transferrin isoform profile (HP:0003642)1.98048528
73Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.97194870
74Abnormality of the pons (HP:0007361)1.97156507
75Chorioretinal atrophy (HP:0000533)1.96647512
76Sclerocornea (HP:0000647)1.95780645
77Hypoplasia of the thymus (HP:0000778)1.95307734
78Constricted visual fields (HP:0001133)1.95068204
79Absent thumb (HP:0009777)1.94088701
80Abnormality of renal resorption (HP:0011038)1.93217877
81Abnormality of urine glucose concentration (HP:0011016)1.93125072
82Glycosuria (HP:0003076)1.93125072
83Medial flaring of the eyebrow (HP:0010747)1.90617017
84Encephalitis (HP:0002383)1.89964780
85Nephronophthisis (HP:0000090)1.88601594
86Leukocytosis (HP:0001974)1.88516302
87Abnormal number of erythroid precursors (HP:0012131)1.87888492
88Abnormal delayed hypersensitivity skin test (HP:0002963)1.87073561
89Hypomagnesemia (HP:0002917)1.86447282
90Pendular nystagmus (HP:0012043)1.84959327
91Recurrent bronchitis (HP:0002837)1.83866442
92Amyotrophic lateral sclerosis (HP:0007354)1.83712112
93Granulocytopenia (HP:0001913)1.83228738
94Hemiplegia (HP:0002301)1.79691754
95Aplasia/Hypoplasia of the spleen (HP:0010451)1.79540751
96Decreased central vision (HP:0007663)1.78194729
97Asplenia (HP:0001746)1.77799596
98Abnormality of the renal medulla (HP:0100957)1.76556494
99Abnormality of magnesium homeostasis (HP:0004921)1.76492009
100Agammaglobulinemia (HP:0004432)1.74124089

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR4.46238616
2TXK3.43980391
3TESK23.17015931
4TLK13.04653854
5BCKDK3.02938568
6ZAK2.97596297
7VRK22.51495928
8TAOK32.37314188
9GRK12.23096823
10LIMK12.16199302
11MUSK2.09575271
12ADRBK21.98976620
13ITK1.88527943
14MAP4K11.87927831
15KIT1.76102760
16FRK1.74550416
17GRK61.66198199
18NUAK11.65585935
19VRK11.57888205
20SYK1.57701950
21WNK41.56210599
22PLK21.53916496
23FES1.53286415
24MAPKAPK31.49686668
25EIF2AK31.42661128
26TAF11.40717226
27TESK11.29455775
28BUB11.28685165
29NME11.24556461
30BMPR1B1.20331627
31MAP3K121.18208427
32CAMKK21.16463676
33PRKCQ1.13156802
34LCK1.08268789
35IKBKB1.07992525
36PIM21.06263047
37BTK1.05504777
38MAP3K111.05362855
39TIE11.04600052
40MAP4K21.02993406
41ZAP701.02102086
42NTRK21.00258068
43TEC0.99962895
44PHKG20.96080802
45PHKG10.96080802
46MST40.95222042
47MAPK130.92387103
48OXSR10.90001666
49LYN0.81241197
50CSK0.79308949
51IKBKE0.74172167
52WNK30.73714316
53INSRR0.72669945
54MAPKAPK50.68440166
55MAP2K70.68368082
56DYRK20.67844400
57PASK0.66932061
58RPS6KA50.65155828
59CAMKK10.64873540
60SCYL20.64650883
61STK160.64051565
62CSNK1G30.62637266
63DAPK10.60342730
64PRKCI0.59543059
65ADRBK10.59071838
66NTRK10.58864446
67CSF1R0.56470755
68CSNK1G20.56469952
69OBSCN0.49972453
70IGF1R0.49239675
71PINK10.48631292
72CAMK2A0.47292413
73MYLK0.46626462
74ATR0.45962605
75NTRK30.45778288
76PRKD30.45712181
77NEK10.45408214
78TSSK60.44912863
79DAPK20.44893608
80PRKCA0.44628468
81PIM10.42312082
82PRKACA0.41967979
83SRPK10.41743856
84PRKCE0.41296921
85CSNK1G10.38383863
86PRKCH0.37564069
87JAK30.36978165
88DAPK30.35160585
89CSNK1A1L0.34564863
90ACVR1B0.34341575
91EPHB20.34097960
92GRK70.32038658
93MATK0.31426717
94HCK0.31354178
95PRKCD0.30786356
96CSNK2A10.29949261
97GRK50.29448275
98PLK30.28940089
99PIK3CA0.27932113
100TNK20.27615824

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053404.55152675
2Proteasome_Homo sapiens_hsa030503.92748865
3Oxidative phosphorylation_Homo sapiens_hsa001903.55876321
4Parkinsons disease_Homo sapiens_hsa050123.15199638
5Graft-versus-host disease_Homo sapiens_hsa053322.81680171
6Autoimmune thyroid disease_Homo sapiens_hsa053202.60938799
7Allograft rejection_Homo sapiens_hsa053302.57653353
8RNA polymerase_Homo sapiens_hsa030202.30336627
9Type I diabetes mellitus_Homo sapiens_hsa049402.29219384
10Antigen processing and presentation_Homo sapiens_hsa046122.25367160
11Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.17514120
12Ribosome_Homo sapiens_hsa030102.14803942
13Intestinal immune network for IgA production_Homo sapiens_hsa046722.12586369
14Phototransduction_Homo sapiens_hsa047442.01930922
15Alzheimers disease_Homo sapiens_hsa050101.95011357
16Huntingtons disease_Homo sapiens_hsa050161.90818901
17Hematopoietic cell lineage_Homo sapiens_hsa046401.90732872
18Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.83586583
19Nitrogen metabolism_Homo sapiens_hsa009101.83260833
20Asthma_Homo sapiens_hsa053101.77828694
21Protein export_Homo sapiens_hsa030601.76320607
22Cardiac muscle contraction_Homo sapiens_hsa042601.70186771
23Linoleic acid metabolism_Homo sapiens_hsa005911.57418052
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.56681970
25Homologous recombination_Homo sapiens_hsa034401.43924260
26Rheumatoid arthritis_Homo sapiens_hsa053231.40607951
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.39807808
28Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.39314947
29T cell receptor signaling pathway_Homo sapiens_hsa046601.35151374
30Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.30723687
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.29416174
32SNARE interactions in vesicular transport_Homo sapiens_hsa041301.21438195
33Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.21365917
34Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.19548348
35Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.17938281
36RNA degradation_Homo sapiens_hsa030181.11115978
37Fanconi anemia pathway_Homo sapiens_hsa034601.10399044
38Basal transcription factors_Homo sapiens_hsa030221.06520640
39Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.03799913
40Pyrimidine metabolism_Homo sapiens_hsa002401.00374524
41Nicotine addiction_Homo sapiens_hsa050330.94569015
42NF-kappa B signaling pathway_Homo sapiens_hsa040640.93274390
43Caffeine metabolism_Homo sapiens_hsa002320.91737234
44Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.89899420
45Purine metabolism_Homo sapiens_hsa002300.89184042
46Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.88328315
47Ether lipid metabolism_Homo sapiens_hsa005650.84655829
48Viral myocarditis_Homo sapiens_hsa054160.83095691
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.82169743
50Systemic lupus erythematosus_Homo sapiens_hsa053220.82134665
51Butanoate metabolism_Homo sapiens_hsa006500.80902388
52Peroxisome_Homo sapiens_hsa041460.73419409
53Propanoate metabolism_Homo sapiens_hsa006400.71786116
54Olfactory transduction_Homo sapiens_hsa047400.68553193
55Shigellosis_Homo sapiens_hsa051310.67049208
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.65771357
57Nucleotide excision repair_Homo sapiens_hsa034200.64882894
58Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.63954633
59Spliceosome_Homo sapiens_hsa030400.62898945
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.61472126
61Collecting duct acid secretion_Homo sapiens_hsa049660.60480467
62Measles_Homo sapiens_hsa051620.59970655
63Mismatch repair_Homo sapiens_hsa034300.59126249
64Morphine addiction_Homo sapiens_hsa050320.58092147
65DNA replication_Homo sapiens_hsa030300.55206300
66Tryptophan metabolism_Homo sapiens_hsa003800.54922689
67Steroid hormone biosynthesis_Homo sapiens_hsa001400.54604524
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51852513
69Regulation of autophagy_Homo sapiens_hsa041400.51610638
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.51305418
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51227948
72Chemical carcinogenesis_Homo sapiens_hsa052040.50452897
73Salmonella infection_Homo sapiens_hsa051320.48416587
74ABC transporters_Homo sapiens_hsa020100.47767686
75Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46931505
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.45613874
77Retinol metabolism_Homo sapiens_hsa008300.43877664
78Metabolic pathways_Homo sapiens_hsa011000.43411537
79NOD-like receptor signaling pathway_Homo sapiens_hsa046210.41738259
80Arachidonic acid metabolism_Homo sapiens_hsa005900.40901474
81Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.40080520
82Sulfur metabolism_Homo sapiens_hsa009200.38994801
83Fat digestion and absorption_Homo sapiens_hsa049750.38926860
84Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37788299
85Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.36998393
86Epstein-Barr virus infection_Homo sapiens_hsa051690.33904933
87Staphylococcus aureus infection_Homo sapiens_hsa051500.33709346
88One carbon pool by folate_Homo sapiens_hsa006700.32660890
89GABAergic synapse_Homo sapiens_hsa047270.30613271
90Taste transduction_Homo sapiens_hsa047420.29269004
91Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.28310894
92beta-Alanine metabolism_Homo sapiens_hsa004100.27254808
93Herpes simplex infection_Homo sapiens_hsa051680.25915032
94Base excision repair_Homo sapiens_hsa034100.25653836
95Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.24822128
96Sulfur relay system_Homo sapiens_hsa041220.24443842
97Malaria_Homo sapiens_hsa051440.23510535
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.19869755
99RNA transport_Homo sapiens_hsa030130.19613279
100Primary bile acid biosynthesis_Homo sapiens_hsa001200.16568039

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »