

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 9.13914354 |
| 2 | cytidine metabolic process (GO:0046087) | 8.64175702 |
| 3 | cytidine catabolic process (GO:0006216) | 8.64175702 |
| 4 | cytidine deamination (GO:0009972) | 8.64175702 |
| 5 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.66288839 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.38542177 |
| 7 | positive regulation of interleukin-8 secretion (GO:2000484) | 5.05127129 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.39137959 |
| 9 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.25133627 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.19070637 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 4.19070637 |
| 12 | regulation of regulatory T cell differentiation (GO:0045589) | 4.03738058 |
| 13 | regulation of interleukin-8 secretion (GO:2000482) | 3.94701385 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.91852536 |
| 15 | actin nucleation (GO:0045010) | 3.87069722 |
| 16 | negative regulation of T cell apoptotic process (GO:0070233) | 3.82821371 |
| 17 | sequestering of actin monomers (GO:0042989) | 3.81466479 |
| 18 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.78027907 |
| 19 | ribosomal small subunit assembly (GO:0000028) | 3.75698429 |
| 20 | respiratory electron transport chain (GO:0022904) | 3.61167513 |
| 21 | electron transport chain (GO:0022900) | 3.55978994 |
| 22 | regulation of activation of Janus kinase activity (GO:0010533) | 3.53994690 |
| 23 | T cell migration (GO:0072678) | 3.53931286 |
| 24 | eosinophil chemotaxis (GO:0048245) | 3.52865140 |
| 25 | regulation of chronic inflammatory response (GO:0002676) | 3.48815066 |
| 26 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.45373014 |
| 27 | protein neddylation (GO:0045116) | 3.41921017 |
| 28 | positive thymic T cell selection (GO:0045059) | 3.41749234 |
| 29 | positive T cell selection (GO:0043368) | 3.41286828 |
| 30 | negative regulation by host of viral transcription (GO:0043922) | 3.40349991 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.39434937 |
| 32 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.38368950 |
| 33 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.35798811 |
| 34 | positive regulation of defense response to virus by host (GO:0002230) | 3.34418612 |
| 35 | cellular response to interleukin-15 (GO:0071350) | 3.34089215 |
| 36 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.30345938 |
| 37 | cytolysis (GO:0019835) | 3.27523539 |
| 38 | negative regulation of viral genome replication (GO:0045071) | 3.27058734 |
| 39 | metallo-sulfur cluster assembly (GO:0031163) | 3.26600089 |
| 40 | iron-sulfur cluster assembly (GO:0016226) | 3.26600089 |
| 41 | platelet dense granule organization (GO:0060155) | 3.24740979 |
| 42 | eosinophil migration (GO:0072677) | 3.20151471 |
| 43 | positive regulation of tolerance induction (GO:0002645) | 3.19615946 |
| 44 | protein complex biogenesis (GO:0070271) | 3.17869828 |
| 45 | proteasome assembly (GO:0043248) | 3.17461837 |
| 46 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.16877999 |
| 47 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.16349363 |
| 48 | behavioral response to nicotine (GO:0035095) | 3.14368197 |
| 49 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.14354405 |
| 50 | termination of RNA polymerase III transcription (GO:0006386) | 3.14354405 |
| 51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.14252211 |
| 52 | negative T cell selection (GO:0043383) | 3.14211435 |
| 53 | positive regulation of lymphocyte migration (GO:2000403) | 3.13350371 |
| 54 | regulation of T cell tolerance induction (GO:0002664) | 3.07212633 |
| 55 | positive regulation of T cell chemotaxis (GO:0010820) | 3.06497043 |
| 56 | regulation of T cell chemotaxis (GO:0010819) | 3.06497043 |
| 57 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.05102644 |
| 58 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.02862041 |
| 59 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.02153577 |
| 60 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.01998058 |
| 61 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.01998058 |
| 62 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.01740796 |
| 63 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.01740796 |
| 64 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.01740796 |
| 65 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.00554406 |
| 66 | regulation of lymphocyte chemotaxis (GO:1901623) | 2.99709637 |
| 67 | chaperone-mediated protein transport (GO:0072321) | 2.98289133 |
| 68 | respiratory chain complex IV assembly (GO:0008535) | 2.97088905 |
| 69 | positive regulation of B cell differentiation (GO:0045579) | 2.96786695 |
| 70 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.94285338 |
| 71 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.93545175 |
| 72 | DNA demethylation (GO:0080111) | 2.91271240 |
| 73 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.90758279 |
| 74 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.89767896 |
| 75 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.89767896 |
| 76 | macrophage chemotaxis (GO:0048246) | 2.89634625 |
| 77 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.88975044 |
| 78 | response to interferon-beta (GO:0035456) | 2.88458370 |
| 79 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.86969773 |
| 80 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.86928375 |
| 81 | positive regulation of cell killing (GO:0031343) | 2.86372270 |
| 82 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.84777468 |
| 83 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.84536837 |
| 84 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.84536837 |
| 85 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.83823391 |
| 86 | DNA dealkylation (GO:0035510) | 2.82150157 |
| 87 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.81287081 |
| 88 | pyrimidine-containing compound catabolic process (GO:0072529) | 2.80662822 |
| 89 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.80280326 |
| 90 | positive regulation of T cell apoptotic process (GO:0070234) | 2.79548619 |
| 91 | T cell costimulation (GO:0031295) | 2.79108910 |
| 92 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.78192550 |
| 93 | positive regulation of T cell migration (GO:2000406) | 2.76447437 |
| 94 | T cell receptor signaling pathway (GO:0050852) | 2.76242164 |
| 95 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.76118899 |
| 96 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.75813310 |
| 97 | lymphocyte costimulation (GO:0031294) | 2.75812554 |
| 98 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.74690588 |
| 99 | NADH dehydrogenase complex assembly (GO:0010257) | 2.74690588 |
| 100 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.74690588 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.04749622 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.28077500 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.90297926 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.67369700 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.47852889 |
| 6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.12521514 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.08806399 |
| 8 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.93943934 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91868717 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.74919510 |
| 11 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.67810413 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.67127836 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.65559031 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.39024652 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.35058131 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.28405466 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.27137230 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.00250692 |
| 19 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.96132302 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.92570890 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91349270 |
| 22 | MYB_26560356_Chip-Seq_TH2_Human | 1.90585343 |
| 23 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.81965747 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.77367692 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.73981371 |
| 26 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.72856871 |
| 27 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.69930695 |
| 28 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63996947 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.61910153 |
| 30 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.56449555 |
| 31 | GATA3_26560356_Chip-Seq_TH2_Human | 1.55521444 |
| 32 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.54727243 |
| 33 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.52067649 |
| 34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.51025368 |
| 35 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.50429468 |
| 36 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.47684341 |
| 37 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.47136084 |
| 38 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.46088523 |
| 39 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.45955770 |
| 40 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.45807479 |
| 41 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.44284313 |
| 42 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.43637898 |
| 43 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.42566701 |
| 44 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.40456652 |
| 45 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.40437967 |
| 46 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.38493803 |
| 47 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.34732131 |
| 48 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.29711914 |
| 49 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.27705313 |
| 50 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.26203627 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25765259 |
| 52 | NCOR_22424771_ChIP-Seq_293T_Human | 1.24324084 |
| 53 | AR_20517297_ChIP-Seq_VCAP_Human | 1.23264716 |
| 54 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.23143805 |
| 55 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.22682218 |
| 56 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.21744405 |
| 57 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21316901 |
| 58 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21316901 |
| 59 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21228828 |
| 60 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.20129730 |
| 61 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.18471438 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.16544630 |
| 63 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.15395391 |
| 64 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.13679062 |
| 65 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12768596 |
| 66 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.12548295 |
| 67 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.09757736 |
| 68 | MYB_26560356_Chip-Seq_TH1_Human | 1.09716818 |
| 69 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08780195 |
| 70 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07547951 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06253554 |
| 72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06253554 |
| 73 | ERA_21632823_ChIP-Seq_H3396_Human | 1.04098442 |
| 74 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.04064401 |
| 75 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.02650349 |
| 76 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.02203495 |
| 77 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.02017536 |
| 78 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.01446779 |
| 79 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.00201847 |
| 80 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.99303154 |
| 81 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.99185631 |
| 82 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.99085239 |
| 83 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.98037296 |
| 84 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97984462 |
| 85 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.97159389 |
| 86 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.95029348 |
| 87 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.94755806 |
| 88 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.94412496 |
| 89 | P300_27268052_Chip-Seq_Bcells_Human | 0.94248020 |
| 90 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.93849396 |
| 91 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.93104310 |
| 92 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.92510379 |
| 93 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.91783563 |
| 94 | EWS_26573619_Chip-Seq_HEK293_Human | 0.91506289 |
| 95 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.91294802 |
| 96 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.89306721 |
| 97 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.89257285 |
| 98 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.88971140 |
| 99 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.88795874 |
| 100 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.88288381 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.57740311 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.65236329 |
| 3 | MP0009785_altered_susceptibility_to | 3.05770858 |
| 4 | MP0009333_abnormal_splenocyte_physiolog | 2.99039374 |
| 5 | MP0002148_abnormal_hypersensitivity_rea | 2.54032447 |
| 6 | MP0003763_abnormal_thymus_physiology | 2.42514555 |
| 7 | MP0004145_abnormal_muscle_electrophysio | 2.22024911 |
| 8 | MP0005000_abnormal_immune_tolerance | 2.18940210 |
| 9 | MP0001873_stomach_inflammation | 2.07684329 |
| 10 | MP0001800_abnormal_humoral_immune | 2.03454435 |
| 11 | MP0002420_abnormal_adaptive_immunity | 2.00519112 |
| 12 | MP0009379_abnormal_foot_pigmentation | 1.96863482 |
| 13 | MP0005025_abnormal_response_to | 1.95034198 |
| 14 | MP0001819_abnormal_immune_cell | 1.93813634 |
| 15 | MP0003866_abnormal_defecation | 1.92922711 |
| 16 | MP0002723_abnormal_immune_serum | 1.92678711 |
| 17 | MP0005387_immune_system_phenotype | 1.90675365 |
| 18 | MP0001790_abnormal_immune_system | 1.90675365 |
| 19 | MP0001905_abnormal_dopamine_level | 1.86251295 |
| 20 | MP0002163_abnormal_gland_morphology | 1.82918941 |
| 21 | MP0002166_altered_tumor_susceptibility | 1.81825151 |
| 22 | MP0006082_CNS_inflammation | 1.69502022 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.64314456 |
| 24 | MP0003786_premature_aging | 1.63324223 |
| 25 | MP0000685_abnormal_immune_system | 1.62773334 |
| 26 | MP0003646_muscle_fatigue | 1.56971196 |
| 27 | MP0008872_abnormal_physiological_respon | 1.56636815 |
| 28 | MP0002452_abnormal_antigen_presenting | 1.56164193 |
| 29 | MP0010155_abnormal_intestine_physiology | 1.52781109 |
| 30 | MP0000716_abnormal_immune_system | 1.51284073 |
| 31 | MP0004147_increased_porphyrin_level | 1.48689520 |
| 32 | MP0002006_tumorigenesis | 1.48688343 |
| 33 | MP0001968_abnormal_touch/_nociception | 1.48175038 |
| 34 | MP0000372_irregular_coat_pigmentation | 1.48090042 |
| 35 | MP0002398_abnormal_bone_marrow | 1.45113447 |
| 36 | MP0002405_respiratory_system_inflammati | 1.43915599 |
| 37 | MP0002933_joint_inflammation | 1.41542215 |
| 38 | MP0001919_abnormal_reproductive_system | 1.41427933 |
| 39 | MP0002277_abnormal_respiratory_mucosa | 1.40152661 |
| 40 | MP0005645_abnormal_hypothalamus_physiol | 1.39425542 |
| 41 | MP0002736_abnormal_nociception_after | 1.34392050 |
| 42 | MP0006292_abnormal_olfactory_placode | 1.33396507 |
| 43 | MP0008875_abnormal_xenobiotic_pharmacok | 1.33360635 |
| 44 | MP0005075_abnormal_melanosome_morpholog | 1.33124415 |
| 45 | MP0002837_dystrophic_cardiac_calcinosis | 1.30025992 |
| 46 | MP0005389_reproductive_system_phenotype | 1.29946648 |
| 47 | MP0006072_abnormal_retinal_apoptosis | 1.29105460 |
| 48 | MP0002102_abnormal_ear_morphology | 1.28939546 |
| 49 | MP0000703_abnormal_thymus_morphology | 1.28844543 |
| 50 | MP0006036_abnormal_mitochondrial_physio | 1.25703652 |
| 51 | MP0002722_abnormal_immune_system | 1.24647282 |
| 52 | MP0002638_abnormal_pupillary_reflex | 1.20805490 |
| 53 | MP0002876_abnormal_thyroid_physiology | 1.20719799 |
| 54 | MP0002138_abnormal_hepatobiliary_system | 1.19534192 |
| 55 | MP0000689_abnormal_spleen_morphology | 1.18490765 |
| 56 | MP0002429_abnormal_blood_cell | 1.18188976 |
| 57 | MP0003806_abnormal_nucleotide_metabolis | 1.17563591 |
| 58 | MP0003045_fibrosis | 1.17388491 |
| 59 | MP0001188_hyperpigmentation | 1.16547092 |
| 60 | MP0001845_abnormal_inflammatory_respons | 1.15506453 |
| 61 | MP0006276_abnormal_autonomic_nervous | 1.14041287 |
| 62 | MP0002822_catalepsy | 1.13902693 |
| 63 | MP0002095_abnormal_skin_pigmentation | 1.13582171 |
| 64 | MP0001853_heart_inflammation | 1.11642325 |
| 65 | MP0005253_abnormal_eye_physiology | 1.10621214 |
| 66 | MP0005551_abnormal_eye_electrophysiolog | 1.08928645 |
| 67 | MP0003011_delayed_dark_adaptation | 1.08756718 |
| 68 | MP0003195_calcinosis | 1.07923798 |
| 69 | MP0005379_endocrine/exocrine_gland_phen | 1.07411219 |
| 70 | MP0005084_abnormal_gallbladder_morpholo | 1.01705642 |
| 71 | MP0001542_abnormal_bone_strength | 1.01640397 |
| 72 | MP0001764_abnormal_homeostasis | 1.01141290 |
| 73 | MP0002419_abnormal_innate_immunity | 1.00012370 |
| 74 | MP0005410_abnormal_fertilization | 0.99893711 |
| 75 | MP0003880_abnormal_central_pattern | 0.99081121 |
| 76 | MP0004142_abnormal_muscle_tone | 0.98129455 |
| 77 | MP0002733_abnormal_thermal_nociception | 0.95098274 |
| 78 | MP0003448_altered_tumor_morphology | 0.94758345 |
| 79 | MP0008873_increased_physiological_sensi | 0.93452876 |
| 80 | MP0008469_abnormal_protein_level | 0.92351083 |
| 81 | MP0001661_extended_life_span | 0.91960754 |
| 82 | MP0009764_decreased_sensitivity_to | 0.91189495 |
| 83 | MP0003436_decreased_susceptibility_to | 0.91094985 |
| 84 | MP0003137_abnormal_impulse_conducting | 0.89941877 |
| 85 | MP0002693_abnormal_pancreas_physiology | 0.88406247 |
| 86 | MP0008058_abnormal_DNA_repair | 0.87909613 |
| 87 | MP0009763_increased_sensitivity_to | 0.87867259 |
| 88 | MP0009745_abnormal_behavioral_response | 0.86174840 |
| 89 | MP0001529_abnormal_vocalization | 0.83562577 |
| 90 | MP0001970_abnormal_pain_threshold | 0.83172227 |
| 91 | MP0008789_abnormal_olfactory_epithelium | 0.82514761 |
| 92 | MP0009765_abnormal_xenobiotic_induced | 0.81644649 |
| 93 | MP0002160_abnormal_reproductive_system | 0.80458798 |
| 94 | MP0003878_abnormal_ear_physiology | 0.79520074 |
| 95 | MP0005377_hearing/vestibular/ear_phenot | 0.79520074 |
| 96 | MP0004742_abnormal_vestibular_system | 0.79370137 |
| 97 | MP0010386_abnormal_urinary_bladder | 0.78231328 |
| 98 | MP0002132_abnormal_respiratory_system | 0.77421554 |
| 99 | MP0005636_abnormal_mineral_homeostasis | 0.75751998 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.75480397 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 5.45268218 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.49712825 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.04321294 |
| 4 | T lymphocytopenia (HP:0005403) | 4.03153176 |
| 5 | Hepatocellular necrosis (HP:0001404) | 3.98501012 |
| 6 | Hypoproteinemia (HP:0003075) | 3.94872302 |
| 7 | Abnormality of T cell number (HP:0011839) | 3.91967275 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.90351098 |
| 9 | Increased CSF lactate (HP:0002490) | 3.90131930 |
| 10 | Increased intramyocellular lipid droplets (HP:0012240) | 3.84653713 |
| 11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.81894763 |
| 12 | IgG deficiency (HP:0004315) | 3.77929072 |
| 13 | Renal Fanconi syndrome (HP:0001994) | 3.67436879 |
| 14 | Lipid accumulation in hepatocytes (HP:0006561) | 3.60427644 |
| 15 | Hepatic necrosis (HP:0002605) | 3.49083818 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.47474600 |
| 17 | Acute encephalopathy (HP:0006846) | 3.37362907 |
| 18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.29389112 |
| 19 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.28331052 |
| 20 | Increased muscle lipid content (HP:0009058) | 3.26684031 |
| 21 | Progressive macrocephaly (HP:0004481) | 3.24598739 |
| 22 | Severe combined immunodeficiency (HP:0004430) | 3.23331486 |
| 23 | Autoimmune hemolytic anemia (HP:0001890) | 3.09627654 |
| 24 | Abnormality of the prostate (HP:0008775) | 3.08384012 |
| 25 | Cerebral edema (HP:0002181) | 2.92263761 |
| 26 | Increased serum lactate (HP:0002151) | 2.91895516 |
| 27 | Abnormality of T cells (HP:0002843) | 2.90767691 |
| 28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.86782097 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.86782097 |
| 30 | Pancreatic cysts (HP:0001737) | 2.85933554 |
| 31 | Molar tooth sign on MRI (HP:0002419) | 2.82091911 |
| 32 | Abnormality of midbrain morphology (HP:0002418) | 2.82091911 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.72844560 |
| 34 | Exertional dyspnea (HP:0002875) | 2.68876966 |
| 35 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.68358428 |
| 36 | Abnormality of eosinophils (HP:0001879) | 2.68140007 |
| 37 | Lactic acidosis (HP:0003128) | 2.61862208 |
| 38 | Increased IgM level (HP:0003496) | 2.59479375 |
| 39 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.55343374 |
| 40 | Optic disc pallor (HP:0000543) | 2.54343499 |
| 41 | Decreased central vision (HP:0007663) | 2.52823266 |
| 42 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.49341479 |
| 43 | Thyroiditis (HP:0100646) | 2.48074674 |
| 44 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.46807169 |
| 45 | Pancytopenia (HP:0001876) | 2.45521048 |
| 46 | Abolished electroretinogram (ERG) (HP:0000550) | 2.41376148 |
| 47 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.39710361 |
| 48 | Combined immunodeficiency (HP:0005387) | 2.38936149 |
| 49 | Hypoalbuminemia (HP:0003073) | 2.36432117 |
| 50 | Abnormal albumin level (HP:0012116) | 2.36432117 |
| 51 | Attenuation of retinal blood vessels (HP:0007843) | 2.33363017 |
| 52 | Methylmalonic acidemia (HP:0002912) | 2.31614477 |
| 53 | Constricted visual fields (HP:0001133) | 2.30268582 |
| 54 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.28058961 |
| 55 | Recurrent cutaneous fungal infections (HP:0011370) | 2.28058961 |
| 56 | True hermaphroditism (HP:0010459) | 2.27501065 |
| 57 | Encephalitis (HP:0002383) | 2.26419373 |
| 58 | Chronic diarrhea (HP:0002028) | 2.22982934 |
| 59 | Hyperalaninemia (HP:0003348) | 2.19284664 |
| 60 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.19284664 |
| 61 | Abnormality of alanine metabolism (HP:0010916) | 2.19284664 |
| 62 | Exercise intolerance (HP:0003546) | 2.18720465 |
| 63 | Eosinophilia (HP:0001880) | 2.15964508 |
| 64 | Generalized aminoaciduria (HP:0002909) | 2.15794241 |
| 65 | Pancreatic fibrosis (HP:0100732) | 2.14533736 |
| 66 | Type 2 muscle fiber atrophy (HP:0003554) | 2.14253614 |
| 67 | Chronic obstructive pulmonary disease (HP:0006510) | 2.12079131 |
| 68 | Obstructive lung disease (HP:0006536) | 2.12079131 |
| 69 | Respiratory failure (HP:0002878) | 2.11383804 |
| 70 | Lethargy (HP:0001254) | 2.11117955 |
| 71 | Panhypogammaglobulinemia (HP:0003139) | 2.08289495 |
| 72 | Stomatitis (HP:0010280) | 2.07571051 |
| 73 | Abnormality of renal resorption (HP:0011038) | 2.06476315 |
| 74 | Respiratory difficulties (HP:0002880) | 2.03811595 |
| 75 | Microretrognathia (HP:0000308) | 2.01121336 |
| 76 | Agammaglobulinemia (HP:0004432) | 2.00191166 |
| 77 | Pendular nystagmus (HP:0012043) | 1.99886875 |
| 78 | Ureteral stenosis (HP:0000071) | 1.99770481 |
| 79 | Methylmalonic aciduria (HP:0012120) | 1.97613889 |
| 80 | Oral leukoplakia (HP:0002745) | 1.93663712 |
| 81 | Meningitis (HP:0001287) | 1.89291929 |
| 82 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88372659 |
| 83 | Pulmonary fibrosis (HP:0002206) | 1.87821002 |
| 84 | Muscle fiber atrophy (HP:0100295) | 1.87058248 |
| 85 | Leukocytosis (HP:0001974) | 1.86197969 |
| 86 | Gangrene (HP:0100758) | 1.84085363 |
| 87 | Hyperphosphaturia (HP:0003109) | 1.84025769 |
| 88 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.81410288 |
| 89 | Dicarboxylic aciduria (HP:0003215) | 1.81410288 |
| 90 | Ureteral obstruction (HP:0006000) | 1.80991866 |
| 91 | Type I transferrin isoform profile (HP:0003642) | 1.80641125 |
| 92 | Abnormality of B cell number (HP:0010975) | 1.80357735 |
| 93 | Recurrent bronchitis (HP:0002837) | 1.79835147 |
| 94 | Ketosis (HP:0001946) | 1.78931094 |
| 95 | Hemiplegia (HP:0002301) | 1.76755643 |
| 96 | Glycosuria (HP:0003076) | 1.76147640 |
| 97 | Abnormality of urine glucose concentration (HP:0011016) | 1.76147640 |
| 98 | Chest pain (HP:0100749) | 1.74786139 |
| 99 | Abnormality of T cell physiology (HP:0011840) | 1.72860246 |
| 100 | Pulmonary infiltrates (HP:0002113) | 1.70750823 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 5.73735390 |
| 2 | KDR | 4.60187512 |
| 3 | TESK2 | 4.20616760 |
| 4 | BCKDK | 3.65735701 |
| 5 | VRK2 | 3.46069656 |
| 6 | MAP4K1 | 2.40953979 |
| 7 | NUAK1 | 2.26178515 |
| 8 | ITK | 2.22500333 |
| 9 | ADRBK2 | 1.99864124 |
| 10 | BUB1 | 1.96632062 |
| 11 | FES | 1.88999514 |
| 12 | TLK1 | 1.84015162 |
| 13 | ZAK | 1.83410519 |
| 14 | MAP3K12 | 1.77166141 |
| 15 | TESK1 | 1.69418521 |
| 16 | STK16 | 1.69362773 |
| 17 | LIMK1 | 1.66844569 |
| 18 | GRK1 | 1.66023489 |
| 19 | VRK1 | 1.65319211 |
| 20 | EIF2AK3 | 1.53031854 |
| 21 | MUSK | 1.42424750 |
| 22 | TRIM28 | 1.37529761 |
| 23 | PRKCQ | 1.36454090 |
| 24 | MAP3K11 | 1.32843916 |
| 25 | SYK | 1.28107832 |
| 26 | MAPKAPK3 | 1.17432830 |
| 27 | LCK | 1.15687509 |
| 28 | MAP4K2 | 1.15608432 |
| 29 | MST4 | 1.11821635 |
| 30 | BMPR1B | 1.11715167 |
| 31 | TEC | 1.10720325 |
| 32 | IKBKB | 1.08267470 |
| 33 | WNK4 | 1.06027710 |
| 34 | CSK | 1.03852690 |
| 35 | IKBKE | 0.98418011 |
| 36 | CSNK1G3 | 0.98177227 |
| 37 | DAPK1 | 0.97629063 |
| 38 | SCYL2 | 0.95992416 |
| 39 | DYRK2 | 0.95882131 |
| 40 | GRK7 | 0.94832161 |
| 41 | GRK6 | 0.94469752 |
| 42 | MAPKAPK5 | 0.93465944 |
| 43 | TAOK3 | 0.91773571 |
| 44 | BTK | 0.90864324 |
| 45 | TIE1 | 0.89243487 |
| 46 | CAMKK2 | 0.88833233 |
| 47 | PIK3CG | 0.87037235 |
| 48 | INSRR | 0.84441996 |
| 49 | NME1 | 0.84269397 |
| 50 | CSF1R | 0.82486743 |
| 51 | OXSR1 | 0.82237420 |
| 52 | MYLK | 0.78840259 |
| 53 | LYN | 0.77700755 |
| 54 | FRK | 0.75865331 |
| 55 | CSNK1G2 | 0.73392529 |
| 56 | TAF1 | 0.71648999 |
| 57 | KIT | 0.71498420 |
| 58 | CSNK1A1L | 0.67306034 |
| 59 | ADRBK1 | 0.64458312 |
| 60 | CSNK1G1 | 0.63467491 |
| 61 | JAK3 | 0.62807956 |
| 62 | TYRO3 | 0.60948073 |
| 63 | MAP2K7 | 0.60671359 |
| 64 | PIM2 | 0.60307639 |
| 65 | PINK1 | 0.60139535 |
| 66 | PIK3CA | 0.59935662 |
| 67 | TBK1 | 0.56070173 |
| 68 | RPS6KA5 | 0.55620070 |
| 69 | TNK2 | 0.52550469 |
| 70 | BCR | 0.52521403 |
| 71 | GRK5 | 0.51261128 |
| 72 | IGF1R | 0.51188946 |
| 73 | OBSCN | 0.50013951 |
| 74 | CAMK2A | 0.49143850 |
| 75 | WNK3 | 0.49022159 |
| 76 | NEK1 | 0.45862917 |
| 77 | ERBB3 | 0.45732680 |
| 78 | MAPK13 | 0.44934429 |
| 79 | PDK2 | 0.44844938 |
| 80 | ATR | 0.44347212 |
| 81 | PHKG2 | 0.44078166 |
| 82 | PHKG1 | 0.44078166 |
| 83 | PRKCG | 0.43242545 |
| 84 | PRKCA | 0.42928409 |
| 85 | AURKA | 0.42862454 |
| 86 | FYN | 0.42750975 |
| 87 | PRKACA | 0.41190055 |
| 88 | STK39 | 0.38797473 |
| 89 | MAP2K6 | 0.37995182 |
| 90 | PIM1 | 0.37326818 |
| 91 | MAP3K5 | 0.37163771 |
| 92 | NME2 | 0.35737493 |
| 93 | EIF2AK2 | 0.35377696 |
| 94 | CSNK2A1 | 0.34305865 |
| 95 | PRKCE | 0.33079030 |
| 96 | CDK19 | 0.31069746 |
| 97 | CSNK2A2 | 0.30602955 |
| 98 | MKNK1 | 0.29595995 |
| 99 | MINK1 | 0.29572275 |
| 100 | DAPK3 | 0.28733865 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.47186502 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.20301602 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.68603736 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.18491435 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.04867807 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.99837095 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.90267480 |
| 8 | Ribosome_Homo sapiens_hsa03010 | 2.76117127 |
| 9 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.70199109 |
| 10 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.55390572 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.43790313 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.39068167 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.99367769 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.98521990 |
| 15 | Protein export_Homo sapiens_hsa03060 | 1.98252603 |
| 16 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.89220442 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.86439743 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.82228433 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.74723510 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.69659906 |
| 21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.65120748 |
| 22 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.60262265 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.58498277 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.52308327 |
| 25 | Phototransduction_Homo sapiens_hsa04744 | 1.36002367 |
| 26 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.24893598 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.19006816 |
| 28 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.17351067 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.13215164 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.08016059 |
| 31 | Viral myocarditis_Homo sapiens_hsa05416 | 1.05586908 |
| 32 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.04403098 |
| 33 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99381134 |
| 34 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.97559574 |
| 35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.97208537 |
| 36 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.96945569 |
| 37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.92290635 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.91913759 |
| 39 | RNA degradation_Homo sapiens_hsa03018 | 0.89557470 |
| 40 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.84328943 |
| 41 | Homologous recombination_Homo sapiens_hsa03440 | 0.83784248 |
| 42 | Measles_Homo sapiens_hsa05162 | 0.82530294 |
| 43 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.82048112 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.81652383 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 0.81008483 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.79174057 |
| 47 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.77473963 |
| 48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.76592085 |
| 49 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.74631201 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73891022 |
| 51 | Salmonella infection_Homo sapiens_hsa05132 | 0.72567896 |
| 52 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.72021368 |
| 53 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.69429337 |
| 54 | Spliceosome_Homo sapiens_hsa03040 | 0.66680085 |
| 55 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.65513876 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65463763 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.64095417 |
| 58 | Mismatch repair_Homo sapiens_hsa03430 | 0.61872378 |
| 59 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.60723891 |
| 60 | Basal transcription factors_Homo sapiens_hsa03022 | 0.60679488 |
| 61 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.60552219 |
| 62 | DNA replication_Homo sapiens_hsa03030 | 0.59765212 |
| 63 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57555878 |
| 64 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.56167019 |
| 65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.55265040 |
| 66 | Nicotine addiction_Homo sapiens_hsa05033 | 0.54704616 |
| 67 | Base excision repair_Homo sapiens_hsa03410 | 0.53510975 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52863968 |
| 69 | RNA transport_Homo sapiens_hsa03013 | 0.52429940 |
| 70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52255807 |
| 71 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.49657477 |
| 72 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.48959684 |
| 73 | Sulfur relay system_Homo sapiens_hsa04122 | 0.48729141 |
| 74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.48172411 |
| 75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48166536 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47402886 |
| 77 | Shigellosis_Homo sapiens_hsa05131 | 0.46536610 |
| 78 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.45951109 |
| 79 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.42549203 |
| 80 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.42251459 |
| 81 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.41954306 |
| 82 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.40208231 |
| 83 | Malaria_Homo sapiens_hsa05144 | 0.40162254 |
| 84 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.39147876 |
| 85 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.38325935 |
| 86 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.38003537 |
| 87 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.36982247 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35841164 |
| 89 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31667153 |
| 90 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.30158093 |
| 91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.27337758 |
| 92 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.25429697 |
| 93 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.24888318 |
| 94 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.22586760 |
| 95 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.21390059 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.20147811 |
| 97 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.19671472 |
| 98 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.19205180 |
| 99 | Taste transduction_Homo sapiens_hsa04742 | 0.17586177 |
| 100 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.16626543 |

