RPS26P35

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.00092491
2DNA deamination (GO:0045006)6.97789244
3energy coupled proton transport, down electrochemical gradient (GO:0015985)6.47709496
4ATP synthesis coupled proton transport (GO:0015986)6.47709496
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.47148913
6regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450916.42436866
7cytidine deamination (GO:0009972)6.27753032
8cytidine metabolic process (GO:0046087)6.27753032
9cytidine catabolic process (GO:0006216)6.27753032
10water-soluble vitamin biosynthetic process (GO:0042364)6.00188166
11chaperone-mediated protein transport (GO:0072321)5.36650054
12pyrimidine ribonucleoside catabolic process (GO:0046133)5.35210260
13protein neddylation (GO:0045116)5.08729173
14proteasome assembly (GO:0043248)4.74514408
15respiratory electron transport chain (GO:0022904)4.74304300
16viral transcription (GO:0019083)4.66910862
17respiratory chain complex IV assembly (GO:0008535)4.65347535
18electron transport chain (GO:0022900)4.63720690
19mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.63552087
20translational termination (GO:0006415)4.51917773
21ribosomal small subunit biogenesis (GO:0042274)4.24184106
22translational elongation (GO:0006414)4.22703003
23ncRNA 3-end processing (GO:0043628)4.18615045
24protein complex biogenesis (GO:0070271)4.15129816
25SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.14770511
26cotranslational protein targeting to membrane (GO:0006613)4.10381466
27protein targeting to ER (GO:0045047)4.07402347
28protein localization to endoplasmic reticulum (GO:0070972)3.91797586
29establishment of protein localization to endoplasmic reticulum (GO:0072599)3.88623437
30cytochrome complex assembly (GO:0017004)3.81571266
31mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.78660981
32mitochondrial respiratory chain complex I assembly (GO:0032981)3.78660981
33NADH dehydrogenase complex assembly (GO:0010257)3.78660981
34mitochondrial respiratory chain complex assembly (GO:0033108)3.73444512
35termination of RNA polymerase III transcription (GO:0006386)3.71037504
36transcription elongation from RNA polymerase III promoter (GO:0006385)3.71037504
37ATP biosynthetic process (GO:0006754)3.52397071
38purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.46310841
39purine nucleoside triphosphate biosynthetic process (GO:0009145)3.45287162
40hydrogen ion transmembrane transport (GO:1902600)3.45105724
41cellular protein complex disassembly (GO:0043624)3.42242841
42translation (GO:0006412)3.40424114
43viral life cycle (GO:0019058)3.31927673
44pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.28132795
45GTP biosynthetic process (GO:0006183)3.27037782
46maturation of SSU-rRNA (GO:0030490)3.24964589
47translational initiation (GO:0006413)3.21164029
48proton transport (GO:0015992)3.19896893
49hydrogen transport (GO:0006818)3.18290990
50mast cell degranulation (GO:0043303)3.17851122
51mast cell activation involved in immune response (GO:0002279)3.17851122
52negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.09300829
53nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.02159746
54establishment of protein localization to mitochondrial membrane (GO:0090151)3.01420144
55ribosomal large subunit biogenesis (GO:0042273)3.01298806
56regulation of regulatory T cell differentiation (GO:0045589)3.00807856
57vitamin biosynthetic process (GO:0009110)3.00583185
58positive regulation of natural killer cell mediated immunity (GO:0002717)2.94724969
59protein targeting to mitochondrion (GO:0006626)2.94624780
60positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)2.94228216
61platelet dense granule organization (GO:0060155)2.91501016
62mast cell activation (GO:0045576)2.91482766
63cellular component biogenesis (GO:0044085)2.89918853
64nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.89672380
65rRNA modification (GO:0000154)2.89314517
66regulation of cellular extravasation (GO:0002691)2.88940210
67negative regulation of T cell differentiation in thymus (GO:0033085)2.88633921
68ribonucleoside triphosphate biosynthetic process (GO:0009201)2.84748783
69negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.81925924
70negative regulation of ligase activity (GO:0051352)2.81925924
71positive regulation of T cell apoptotic process (GO:0070234)2.79529757
72pseudouridine synthesis (GO:0001522)2.77259364
73regulation of cellular amino acid metabolic process (GO:0006521)2.75573420
74peptidyl-histidine modification (GO:0018202)2.74369681
75pyrimidine nucleoside catabolic process (GO:0046135)2.73880057
76protein targeting to membrane (GO:0006612)2.72748574
77establishment of protein localization to mitochondrion (GO:0072655)2.72214156
78UTP biosynthetic process (GO:0006228)2.70716500
79positive regulation of prostaglandin secretion (GO:0032308)2.69469492
80exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.68490057
81response to interferon-beta (GO:0035456)2.67143878
82positive regulation of granulocyte differentiation (GO:0030854)2.66701960
83positive regulation of B cell differentiation (GO:0045579)2.66581484
84protein complex disassembly (GO:0043241)2.66518814
85regulation of mitochondrial translation (GO:0070129)2.65646771
86rRNA metabolic process (GO:0016072)2.64925813
87rRNA processing (GO:0006364)2.62734751
88positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.62074012
89positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.61992404
90DNA double-strand break processing (GO:0000729)2.61749500
91regulation of chronic inflammatory response (GO:0002676)2.60508618
92metallo-sulfur cluster assembly (GO:0031163)2.60387242
93iron-sulfur cluster assembly (GO:0016226)2.60387242
94macromolecular complex disassembly (GO:0032984)2.60221372
95DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.60074071
96pyrimidine nucleotide catabolic process (GO:0006244)2.58598630
97T cell migration (GO:0072678)2.58250995
98purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.56822341
99antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.56095863
100regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.55634848

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.93018462
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse4.70504740
3GABP_17652178_ChIP-ChIP_JURKAT_Human4.34792841
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.13834894
5EST1_17652178_ChIP-ChIP_JURKAT_Human4.03805332
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.42731660
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.28718004
8VDR_23849224_ChIP-Seq_CD4+_Human2.92267679
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.90740618
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.85898798
11BP1_19119308_ChIP-ChIP_Hs578T_Human2.78557748
12IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.50295225
13MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.50062546
14MYC_18555785_ChIP-Seq_MESCs_Mouse2.47456772
15FOXP3_21729870_ChIP-Seq_TREG_Human2.45983664
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.43542626
17NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.41061446
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36182437
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.35788308
20IRF8_22096565_ChIP-ChIP_GC-B_Human2.26219586
21HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.23160702
22ELK1_19687146_ChIP-ChIP_HELA_Human2.21002250
23CREB1_15753290_ChIP-ChIP_HEK293T_Human2.20948498
24MYC_18358816_ChIP-ChIP_MESCs_Mouse1.96664064
25PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.92839875
26SRF_21415370_ChIP-Seq_HL-1_Mouse1.89650068
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.75901549
28ZNF274_21170338_ChIP-Seq_K562_Hela1.75544810
29FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.73707192
30VDR_22108803_ChIP-Seq_LS180_Human1.72564309
31IGF1R_20145208_ChIP-Seq_DFB_Human1.68960932
32YY1_21170310_ChIP-Seq_MESCs_Mouse1.68729416
33IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.68667028
34THAP11_20581084_ChIP-Seq_MESCs_Mouse1.68569078
35EZH2_22144423_ChIP-Seq_EOC_Human1.60183079
36SOX2_18555785_ChIP-Seq_MESCs_Mouse1.57970356
37E2F4_17652178_ChIP-ChIP_JURKAT_Human1.55826293
38EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.55445625
39POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.54971214
40IRF8_21731497_ChIP-ChIP_J774_Mouse1.51402239
41MYC_19030024_ChIP-ChIP_MESCs_Mouse1.47560373
42MYC_18940864_ChIP-ChIP_HL60_Human1.45613593
43HOXB4_20404135_ChIP-ChIP_EML_Mouse1.44628629
44TP53_22573176_ChIP-Seq_HFKS_Human1.42250553
45SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.38424173
46CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.37231950
47STAT4_19710469_ChIP-ChIP_TH1__Mouse1.34820179
48CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.32604032
49XRN2_22483619_ChIP-Seq_HELA_Human1.31533066
50CIITA_25753668_ChIP-Seq_RAJI_Human1.30917807
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.30831225
52FLI1_27457419_Chip-Seq_LIVER_Mouse1.27665662
53CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.27659377
54TTF2_22483619_ChIP-Seq_HELA_Human1.26538606
55GATA3_26560356_Chip-Seq_TH2_Human1.26346530
56POU5F1_16153702_ChIP-ChIP_HESCs_Human1.21554837
57MYB_26560356_Chip-Seq_TH2_Human1.19462273
58STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.18586258
59EWS_26573619_Chip-Seq_HEK293_Human1.18500084
60FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.13862770
61MYC_19079543_ChIP-ChIP_MESCs_Mouse1.13354629
62E2F1_18555785_ChIP-Seq_MESCs_Mouse1.07693392
63FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07407518
64EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.07131955
65FOXA1_27270436_Chip-Seq_PROSTATE_Human1.04284499
66FOXA1_25329375_ChIP-Seq_VCAP_Human1.04284499
67NANOG_20526341_ChIP-Seq_ESCs_Human1.04241704
68HTT_18923047_ChIP-ChIP_STHdh_Human1.02715991
69ELK1_22589737_ChIP-Seq_MCF10A_Human1.01806242
70AR_20517297_ChIP-Seq_VCAP_Human1.00651008
71TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.00498371
72GABP_19822575_ChIP-Seq_HepG2_Human0.99832933
73PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.98944201
74MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.98288860
75RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.97819071
76CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.96943424
77NCOR_22424771_ChIP-Seq_293T_Human0.96893670
78DCP1A_22483619_ChIP-Seq_HELA_Human0.96793449
79EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.96455365
80LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.96422665
81PCGF2_27294783_Chip-Seq_ESCs_Mouse0.95128633
82TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.93585763
83RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.93542292
84RUNX_20019798_ChIP-Seq_JUKART_Human0.91266202
85CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88965982
86GATA3_21878914_ChIP-Seq_MCF-7_Human0.88567178
87GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.84985665
88ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.84906151
89GATA3_27048872_Chip-Seq_THYMUS_Human0.84206340
90TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.82809223
91RBPJ_21746931_ChIP-Seq_IB4_Human0.82564738
92GATA6_21074721_ChIP-Seq_CACO-2_Human0.82072223
93P53_21459846_ChIP-Seq_SAOS-2_Human0.81843068
94ER_23166858_ChIP-Seq_MCF-7_Human0.81230999
95BCL6_27268052_Chip-Seq_Bcells_Human0.80851440
96TAF2_19829295_ChIP-Seq_ESCs_Human0.80614994
97CTCF_18555785_ChIP-Seq_MESCs_Mouse0.80205857
98P300_27268052_Chip-Seq_Bcells_Human0.80162148
99PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.79760978
100MYC_19829295_ChIP-Seq_ESCs_Human0.79221764

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to5.04673581
2MP0001873_stomach_inflammation3.47923933
3MP0009379_abnormal_foot_pigmentation3.37627916
4MP0003786_premature_aging2.94143752
5MP0003646_muscle_fatigue2.73082710
6MP0004145_abnormal_muscle_electrophysio2.46688615
7MP0009333_abnormal_splenocyte_physiolog2.44062706
8MP0003763_abnormal_thymus_physiology2.33147128
9MP0002277_abnormal_respiratory_mucosa2.32150351
10MP0006072_abnormal_retinal_apoptosis2.27895859
11MP0001835_abnormal_antigen_presentation2.26523105
12MP0003123_paternal_imprinting2.18641786
13MP0001919_abnormal_reproductive_system2.11277514
14MP0001800_abnormal_humoral_immune2.01098709
15MP0003693_abnormal_embryo_hatching2.00791119
16MP0009785_altered_susceptibility_to1.99406113
17MP0003011_delayed_dark_adaptation1.91005012
18MP0000372_irregular_coat_pigmentation1.90330547
19MP0005000_abnormal_immune_tolerance1.85666452
20MP0008872_abnormal_physiological_respon1.85291949
21MP0008995_early_reproductive_senescence1.82957776
22MP0008875_abnormal_xenobiotic_pharmacok1.78438169
23MP0006292_abnormal_olfactory_placode1.76166097
24MP0002933_joint_inflammation1.71446237
25MP0003787_abnormal_imprinting1.70415283
26MP0003866_abnormal_defecation1.69838652
27MP0002723_abnormal_immune_serum1.66183898
28MP0002420_abnormal_adaptive_immunity1.63021398
29MP0001819_abnormal_immune_cell1.56326637
30MP0004147_increased_porphyrin_level1.54699233
31MP0002148_abnormal_hypersensitivity_rea1.53477102
32MP0005389_reproductive_system_phenotype1.49342042
33MP0005646_abnormal_pituitary_gland1.46451614
34MP0003724_increased_susceptibility_to1.44685733
35MP0005084_abnormal_gallbladder_morpholo1.44081640
36MP0003567_abnormal_fetal_cardiomyocyte1.43885649
37MP0001348_abnormal_lacrimal_gland1.43444066
38MP0002837_dystrophic_cardiac_calcinosis1.40616899
39MP0005645_abnormal_hypothalamus_physiol1.38924949
40MP0002452_abnormal_antigen_presenting1.38881098
41MP0001845_abnormal_inflammatory_respons1.36488533
42MP0005025_abnormal_response_to1.34341862
43MP0010155_abnormal_intestine_physiology1.33548280
44MP0005464_abnormal_platelet_physiology1.24687607
45MP0008058_abnormal_DNA_repair1.23931523
46MP0006082_CNS_inflammation1.23879711
47MP0001905_abnormal_dopamine_level1.23228042
48MP0002166_altered_tumor_susceptibility1.22315504
49MP0004885_abnormal_endolymph1.22036054
50MP0001790_abnormal_immune_system1.20354539
51MP0005387_immune_system_phenotype1.20354539
52MP0008007_abnormal_cellular_replicative1.20280949
53MP0000716_abnormal_immune_system1.19478058
54MP0002405_respiratory_system_inflammati1.17249061
55MP0004957_abnormal_blastocyst_morpholog1.15224263
56MP0002138_abnormal_hepatobiliary_system1.11911257
57MP0004142_abnormal_muscle_tone1.10904935
58MP0002006_tumorigenesis1.09887943
59MP0001485_abnormal_pinna_reflex1.09588326
60MP0002398_abnormal_bone_marrow1.08382661
61MP0005379_endocrine/exocrine_gland_phen1.07744632
62MP0005167_abnormal_blood-brain_barrier1.07483796
63MP0000703_abnormal_thymus_morphology1.05762689
64MP0002163_abnormal_gland_morphology1.04394249
65MP0003195_calcinosis1.03154553
66MP0005253_abnormal_eye_physiology1.01731968
67MP0005636_abnormal_mineral_homeostasis1.00296618
68MP0000689_abnormal_spleen_morphology0.99784506
69MP0006036_abnormal_mitochondrial_physio0.98524753
70MP0001765_abnormal_ion_homeostasis0.97372901
71MP0003718_maternal_effect0.96786378
72MP0002722_abnormal_immune_system0.93352895
73MP0005085_abnormal_gallbladder_physiolo0.93310625
74MP0002429_abnormal_blood_cell0.93186763
75MP0003186_abnormal_redox_activity0.93068667
76MP0008775_abnormal_heart_ventricle0.90574226
77MP0001984_abnormal_olfaction0.90216298
78MP0003806_abnormal_nucleotide_metabolis0.88586124
79MP0008877_abnormal_DNA_methylation0.85651275
80MP0004742_abnormal_vestibular_system0.85287505
81MP0001764_abnormal_homeostasis0.84611389
82MP0009763_increased_sensitivity_to0.84297546
83MP0000685_abnormal_immune_system0.83444017
84MP0009643_abnormal_urine_homeostasis0.83087745
85MP0003941_abnormal_skin_development0.82964729
86MP0001663_abnormal_digestive_system0.82752369
87MP0002735_abnormal_chemical_nociception0.82651133
88MP0002160_abnormal_reproductive_system0.82542495
89MP0005410_abnormal_fertilization0.82364332
90MP0005551_abnormal_eye_electrophysiolog0.80885247
91MP0002019_abnormal_tumor_incidence0.80802452
92MP0005360_urolithiasis0.80787817
93MP0008469_abnormal_protein_level0.80608768
94MP0001968_abnormal_touch/_nociception0.80597083
95MP0006276_abnormal_autonomic_nervous0.80359574
96MP0002419_abnormal_innate_immunity0.80348290
97MP0009745_abnormal_behavioral_response0.77054784
98MP0002736_abnormal_nociception_after0.76215079
99MP0005166_decreased_susceptibility_to0.73237591
100MP0009384_cardiac_valve_regurgitation0.72195873

Predicted human phenotypes

RankGene SetZ-score
1Aplastic anemia (HP:0001915)5.63869651
2Increased hepatocellular lipid droplets (HP:0006565)4.87397458
3Acute necrotizing encephalopathy (HP:0006965)4.48640524
4Lipid accumulation in hepatocytes (HP:0006561)4.27553518
5Mitochondrial inheritance (HP:0001427)4.14527419
6Abnormal mitochondria in muscle tissue (HP:0008316)4.00075732
7Rib fusion (HP:0000902)3.90624890
8Renal Fanconi syndrome (HP:0001994)3.84966687
9Progressive macrocephaly (HP:0004481)3.83221356
10Abnormal number of erythroid precursors (HP:0012131)3.73393534
11Increased CSF lactate (HP:0002490)3.72947633
12Increased intramyocellular lipid droplets (HP:0012240)3.64708844
13Acute encephalopathy (HP:0006846)3.58935064
14Abnormality of cells of the erythroid lineage (HP:0012130)3.57556286
15Exertional dyspnea (HP:0002875)3.37816528
16IgG deficiency (HP:0004315)3.16661008
17Hepatocellular necrosis (HP:0001404)3.09252986
18Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.01127409
19Absent/shortened dynein arms (HP:0200106)2.92980253
20Dynein arm defect of respiratory motile cilia (HP:0012255)2.92980253
21T lymphocytopenia (HP:0005403)2.91728252
22Increased muscle lipid content (HP:0009058)2.91172486
23Cerebral edema (HP:0002181)2.90161144
24Abnormal respiratory epithelium morphology (HP:0012253)2.84192795
25Abnormal respiratory motile cilium morphology (HP:0005938)2.84192795
26Respiratory difficulties (HP:0002880)2.82935473
27Reduced antithrombin III activity (HP:0001976)2.82234669
28Decreased activity of mitochondrial respiratory chain (HP:0008972)2.81373703
29Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.81373703
30Abnormality of T cell number (HP:0011839)2.80497929
31Hepatic necrosis (HP:0002605)2.70869596
32Constricted visual fields (HP:0001133)2.70106494
33Confusion (HP:0001289)2.68666756
34Macrocytic anemia (HP:0001972)2.67601858
35Increased serum lactate (HP:0002151)2.64847120
36Reticulocytopenia (HP:0001896)2.63392045
37Hypoproteinemia (HP:0003075)2.54398795
383-Methylglutaconic aciduria (HP:0003535)2.51935795
39Stomatitis (HP:0010280)2.46021468
40Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.43249312
41Metabolic alkalosis (HP:0200114)2.42930014
42Pancreatic fibrosis (HP:0100732)2.40637796
43Abnormal ciliary motility (HP:0012262)2.39693183
44Pancytopenia (HP:0001876)2.36283983
45Exercise intolerance (HP:0003546)2.36081610
46Methylmalonic aciduria (HP:0012120)2.36069225
47Pallor (HP:0000980)2.35608460
48Hypoplasia of the thymus (HP:0000778)2.33359742
49Abolished electroretinogram (ERG) (HP:0000550)2.32950895
50Abnormality of renal resorption (HP:0011038)2.30931872
51Optic disc pallor (HP:0000543)2.29597987
52Colon cancer (HP:0003003)2.28285909
53Abnormal respiratory motile cilium physiology (HP:0012261)2.25151388
54Lethargy (HP:0001254)2.25013146
55Absent thumb (HP:0009777)2.24815914
56Hypoplasia of the uterus (HP:0000013)2.24403973
57Abnormality of T cells (HP:0002843)2.22310425
58Hyperphosphaturia (HP:0003109)2.18375844
59Hyperglycinemia (HP:0002154)2.18356440
60Aplasia/hypoplasia of the uterus (HP:0008684)2.18038573
61Lactic acidosis (HP:0003128)2.17969841
62Oral leukoplakia (HP:0002745)2.17369881
63Absent rod-and cone-mediated responses on ERG (HP:0007688)2.16279783
64Hypokalemic alkalosis (HP:0001949)2.15702986
65Glycosuria (HP:0003076)2.13061647
66Abnormality of urine glucose concentration (HP:0011016)2.13061647
67Severe combined immunodeficiency (HP:0004430)2.12060422
68Methylmalonic acidemia (HP:0002912)2.08328652
69Anomalous pulmonary venous return (HP:0010772)2.07839477
70Abnormal delayed hypersensitivity skin test (HP:0002963)2.07492119
71IgM deficiency (HP:0002850)1.98484668
72Abnormality of the prostate (HP:0008775)1.97955396
73Pancreatic cysts (HP:0001737)1.96785830
74Respiratory failure (HP:0002878)1.92270961
75Congenital stationary night blindness (HP:0007642)1.91931342
76Pendular nystagmus (HP:0012043)1.90953753
77Decreased electroretinogram (ERG) amplitude (HP:0000654)1.89125775
78Polyuria (HP:0000103)1.88939463
79Polydipsia (HP:0001959)1.86273762
80Abnormal drinking behavior (HP:0030082)1.86273762
81Large for gestational age (HP:0001520)1.83329969
82Alkalosis (HP:0001948)1.82949892
83Tetany (HP:0001281)1.82645262
84Panhypogammaglobulinemia (HP:0003139)1.82608570
85Increased IgM level (HP:0003496)1.81383052
86Abnormality of the pulmonary veins (HP:0011718)1.76764761
87Thyroiditis (HP:0100646)1.75077800
88Abnormality of eosinophils (HP:0001879)1.75068847
89Leukodystrophy (HP:0002415)1.74747815
90Abnormality of B cell number (HP:0010975)1.74035482
91Abnormality of placental membranes (HP:0011409)1.73486469
92Amniotic constriction ring (HP:0009775)1.73486469
93Abnormal protein glycosylation (HP:0012346)1.72130457
94Abnormal glycosylation (HP:0012345)1.72130457
95Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.72130457
96Abnormal protein N-linked glycosylation (HP:0012347)1.72130457
97Attenuation of retinal blood vessels (HP:0007843)1.71462596
98Chronic sinusitis (HP:0011109)1.70147852
99Respiratory distress (HP:0002098)1.69690937
100Pancreatic islet-cell hyperplasia (HP:0004510)1.69429222

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TIE15.25441807
2VRK24.43522836
3ZAK3.91938903
4MST43.90953396
5TLK13.85281620
6TXK2.77462598
7TESK22.68753060
8VRK12.57439814
9TNK22.37332308
10GRK12.28081962
11MAP4K12.21773753
12KDR2.17700703
13TEC2.17417751
14TAOK31.96069952
15ADRBK21.93897563
16BMPR1B1.88590309
17NUAK11.81469311
18FES1.78186957
19ZAP701.68532904
20TNIK1.64162168
21BUB11.63677441
22PBK1.59456426
23ITK1.55099617
24BCKDK1.50066315
25RPS6KA41.47950786
26SYK1.35121481
27NME21.22599495
28STK38L1.22368967
29BTK1.20307975
30PLK41.17189916
31TAF11.16462982
32MAP3K121.15558732
33SCYL21.15257594
34GRK61.11823914
35CSK1.03632402
36WNK40.92314059
37NME10.87923415
38PASK0.82453436
39MATK0.78230719
40INSRR0.78200001
41CDK80.74281498
42PLK30.74254056
43EIF2AK10.71022552
44GRK70.71001389
45DYRK20.70139490
46PLK20.69557745
47PDK20.69542518
48ATR0.65775749
49CSF1R0.64383345
50FRK0.63526363
51SRPK10.61249536
52STK40.59854005
53RPS6KA50.57823856
54LYN0.57689168
55DAPK20.57076309
56PRKCQ0.56492574
57CSNK1G30.56160096
58LCK0.52517033
59CDC70.52344689
60MYLK0.51993500
61GRK50.50474043
62CSNK1G10.49777107
63CSNK1G20.48035563
64PIM10.47562888
65CCNB10.47088216
66HCK0.46614917
67DAPK10.45925834
68IKBKB0.44756386
69LRRK20.44517947
70KIT0.44505720
71CSNK2A10.44019518
72ADRBK10.43130884
73CSNK2A20.43081294
74OXSR10.43011014
75PLK10.42853938
76MAP3K110.42191236
77STK160.41015764
78PKN10.39339482
79WNK30.39125976
80AURKB0.38246705
81STK240.38236386
82CSNK1A1L0.37468606
83AURKA0.36657021
84STK390.35903728
85TGFBR10.35317118
86INSR0.35248379
87PRKACA0.34463267
88TYRO30.34172766
89OBSCN0.32781835
90CAMK10.31777534
91PAK30.31513533
92EIF2AK30.30733235
93NEK20.29038955
94PRKCA0.27665417
95PHKG20.27502578
96PHKG10.27502578
97MAPKAPK50.27386830
98ACVR1B0.25254102
99FGFR20.24995073
100DAPK30.23741920

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.61829642
2Oxidative phosphorylation_Homo sapiens_hsa001904.34905371
3Parkinsons disease_Homo sapiens_hsa050123.65360227
4Proteasome_Homo sapiens_hsa030503.52472570
5RNA polymerase_Homo sapiens_hsa030203.19895709
6Primary immunodeficiency_Homo sapiens_hsa053402.86312517
7Asthma_Homo sapiens_hsa053102.84474403
8Allograft rejection_Homo sapiens_hsa053302.74243621
9Autoimmune thyroid disease_Homo sapiens_hsa053202.64001147
10Homologous recombination_Homo sapiens_hsa034402.58512742
11Alzheimers disease_Homo sapiens_hsa050102.47866129
12Huntingtons disease_Homo sapiens_hsa050162.36054504
13Graft-versus-host disease_Homo sapiens_hsa053322.28471767
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.27464871
15Cardiac muscle contraction_Homo sapiens_hsa042602.19207380
16Intestinal immune network for IgA production_Homo sapiens_hsa046722.17558853
17Protein export_Homo sapiens_hsa030601.84661190
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.82017377
19Type I diabetes mellitus_Homo sapiens_hsa049401.80292769
20Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.64788626
21Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.61023858
22Antigen processing and presentation_Homo sapiens_hsa046121.54562529
23Mismatch repair_Homo sapiens_hsa034301.49229640
24One carbon pool by folate_Homo sapiens_hsa006701.36076671
25Hematopoietic cell lineage_Homo sapiens_hsa046401.35702497
26Rheumatoid arthritis_Homo sapiens_hsa053231.31941731
27Fanconi anemia pathway_Homo sapiens_hsa034601.28547025
28Pyrimidine metabolism_Homo sapiens_hsa002401.27262156
29Basal transcription factors_Homo sapiens_hsa030221.26546802
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.18719952
31Spliceosome_Homo sapiens_hsa030401.15600888
32Nucleotide excision repair_Homo sapiens_hsa034201.15320374
33Linoleic acid metabolism_Homo sapiens_hsa005911.13818337
34DNA replication_Homo sapiens_hsa030301.07817678
35Purine metabolism_Homo sapiens_hsa002301.06943021
36Peroxisome_Homo sapiens_hsa041461.06816434
37Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99088257
38Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.94079415
39Viral myocarditis_Homo sapiens_hsa054160.93378411
40Retinol metabolism_Homo sapiens_hsa008300.87692750
41alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.86620589
42Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.85118669
43Systemic lupus erythematosus_Homo sapiens_hsa053220.84718331
44Nitrogen metabolism_Homo sapiens_hsa009100.82518905
45Sulfur metabolism_Homo sapiens_hsa009200.81103670
46RNA degradation_Homo sapiens_hsa030180.79398433
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.78643066
48T cell receptor signaling pathway_Homo sapiens_hsa046600.78426489
49Phototransduction_Homo sapiens_hsa047440.77758170
50Staphylococcus aureus infection_Homo sapiens_hsa051500.75255377
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.75045705
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.68941865
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.68274114
54Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.67964499
55Chemical carcinogenesis_Homo sapiens_hsa052040.66991361
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.66540167
57NF-kappa B signaling pathway_Homo sapiens_hsa040640.61203572
58Metabolic pathways_Homo sapiens_hsa011000.58813579
592-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58696231
60Fat digestion and absorption_Homo sapiens_hsa049750.58688631
61Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.58462573
62Collecting duct acid secretion_Homo sapiens_hsa049660.58121906
63Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.58009015
64Malaria_Homo sapiens_hsa051440.56549645
65Arginine biosynthesis_Homo sapiens_hsa002200.55116869
66RNA transport_Homo sapiens_hsa030130.52331978
67Caffeine metabolism_Homo sapiens_hsa002320.51465442
68Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50607927
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.46572030
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46050072
71Arachidonic acid metabolism_Homo sapiens_hsa005900.44013228
72Glutathione metabolism_Homo sapiens_hsa004800.38767100
73Epstein-Barr virus infection_Homo sapiens_hsa051690.38296394
74Primary bile acid biosynthesis_Homo sapiens_hsa001200.34072640
75Salivary secretion_Homo sapiens_hsa049700.33404073
76Base excision repair_Homo sapiens_hsa034100.33349062
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.31660320
78Pyruvate metabolism_Homo sapiens_hsa006200.31260778
79Sulfur relay system_Homo sapiens_hsa041220.30664169
80Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.28972768
81Folate biosynthesis_Homo sapiens_hsa007900.26214972
82Fatty acid elongation_Homo sapiens_hsa000620.25991189
83Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.25887010
84Cysteine and methionine metabolism_Homo sapiens_hsa002700.25113667
85Olfactory transduction_Homo sapiens_hsa047400.24736099
86Vitamin digestion and absorption_Homo sapiens_hsa049770.22960769
87Propanoate metabolism_Homo sapiens_hsa006400.21036655
88Tryptophan metabolism_Homo sapiens_hsa003800.19724177
89Ether lipid metabolism_Homo sapiens_hsa005650.19537497
90Starch and sucrose metabolism_Homo sapiens_hsa005000.19505580
91Selenocompound metabolism_Homo sapiens_hsa004500.18828930
92Ovarian steroidogenesis_Homo sapiens_hsa049130.18443596
93Leishmaniasis_Homo sapiens_hsa051400.17296036
94Herpes simplex infection_Homo sapiens_hsa051680.15093240
95Maturity onset diabetes of the young_Homo sapiens_hsa049500.15053944
96Drug metabolism - other enzymes_Homo sapiens_hsa009830.14363938
97Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.12983590
98Pancreatic secretion_Homo sapiens_hsa049720.10722861
99Glycerolipid metabolism_Homo sapiens_hsa005610.10253328
100Mineral absorption_Homo sapiens_hsa049780.10086123

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »