

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.27624055 |
| 2 | viral transcription (GO:0019083) | 6.89851497 |
| 3 | translational termination (GO:0006415) | 6.56080297 |
| 4 | ribosomal small subunit biogenesis (GO:0042274) | 6.11125839 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.74307155 |
| 6 | protein targeting to ER (GO:0045047) | 5.67551924 |
| 7 | cotranslational protein targeting to membrane (GO:0006613) | 5.66947915 |
| 8 | maturation of SSU-rRNA (GO:0030490) | 5.62439683 |
| 9 | translational elongation (GO:0006414) | 5.61828649 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.39960782 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 5.37121632 |
| 12 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 5.14653306 |
| 13 | substrate-independent telencephalic tangential migration (GO:0021826) | 5.14653306 |
| 14 | viral life cycle (GO:0019058) | 5.07837061 |
| 15 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.05174539 |
| 16 | cellular protein complex disassembly (GO:0043624) | 4.99607586 |
| 17 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.77107623 |
| 18 | behavioral response to nicotine (GO:0035095) | 4.69097091 |
| 19 | protein neddylation (GO:0045116) | 4.54935162 |
| 20 | somite development (GO:0061053) | 4.46995715 |
| 21 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 4.46282261 |
| 22 | protein complex disassembly (GO:0043241) | 4.30346355 |
| 23 | ATP synthesis coupled proton transport (GO:0015986) | 4.21248210 |
| 24 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.21248210 |
| 25 | translational initiation (GO:0006413) | 4.20004017 |
| 26 | macromolecular complex disassembly (GO:0032984) | 4.04807192 |
| 27 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.96269459 |
| 28 | protein complex biogenesis (GO:0070271) | 3.88694374 |
| 29 | protein targeting to membrane (GO:0006612) | 3.88267796 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.83432351 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 3.83432351 |
| 32 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.83432351 |
| 33 | GTP biosynthetic process (GO:0006183) | 3.80593981 |
| 34 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.77747484 |
| 35 | protein polyglutamylation (GO:0018095) | 3.76137168 |
| 36 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 3.72074479 |
| 37 | chaperone-mediated protein transport (GO:0072321) | 3.70971353 |
| 38 | axon ensheathment in central nervous system (GO:0032291) | 3.65234014 |
| 39 | central nervous system myelination (GO:0022010) | 3.65234014 |
| 40 | cell proliferation in forebrain (GO:0021846) | 3.64115049 |
| 41 | nonmotile primary cilium assembly (GO:0035058) | 3.63996179 |
| 42 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.55368128 |
| 43 | response to pheromone (GO:0019236) | 3.54093158 |
| 44 | translation (GO:0006412) | 3.47842082 |
| 45 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.45698190 |
| 46 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.44470684 |
| 47 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.44345828 |
| 48 | neuron fate determination (GO:0048664) | 3.41559760 |
| 49 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.38553377 |
| 50 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.37686146 |
| 51 | mRNA catabolic process (GO:0006402) | 3.36838387 |
| 52 | radial glial cell differentiation (GO:0060019) | 3.35652958 |
| 53 | tongue development (GO:0043586) | 3.35149976 |
| 54 | epithelial cilium movement (GO:0003351) | 3.34394010 |
| 55 | nephron tubule morphogenesis (GO:0072078) | 3.29946928 |
| 56 | nephron epithelium morphogenesis (GO:0072088) | 3.29946928 |
| 57 | ribosomal large subunit biogenesis (GO:0042273) | 3.29281599 |
| 58 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.28746615 |
| 59 | rRNA catabolic process (GO:0016075) | 3.28042584 |
| 60 | base-excision repair, AP site formation (GO:0006285) | 3.25487675 |
| 61 | UTP biosynthetic process (GO:0006228) | 3.17369245 |
| 62 | regulation of chronic inflammatory response (GO:0002676) | 3.16037568 |
| 63 | DNA deamination (GO:0045006) | 3.13370314 |
| 64 | cellular component biogenesis (GO:0044085) | 3.12519870 |
| 65 | positive regulation of organelle assembly (GO:1902117) | 3.12443176 |
| 66 | respiratory electron transport chain (GO:0022904) | 3.08433228 |
| 67 | regulation of immunoglobulin secretion (GO:0051023) | 3.08413080 |
| 68 | electron transport chain (GO:0022900) | 3.07498444 |
| 69 | UTP metabolic process (GO:0046051) | 3.03820770 |
| 70 | RNA catabolic process (GO:0006401) | 3.00017834 |
| 71 | axonemal dynein complex assembly (GO:0070286) | 2.98737206 |
| 72 | intraciliary transport (GO:0042073) | 2.98673912 |
| 73 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.98302546 |
| 74 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.96240600 |
| 75 | motile cilium assembly (GO:0044458) | 2.94269254 |
| 76 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.93316420 |
| 77 | platelet dense granule organization (GO:0060155) | 2.92768071 |
| 78 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.91305296 |
| 79 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.90355143 |
| 80 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.85249375 |
| 81 | pattern specification involved in kidney development (GO:0061004) | 2.82732621 |
| 82 | negative regulation of telomere maintenance (GO:0032205) | 2.79881023 |
| 83 | cellular response to interferon-beta (GO:0035458) | 2.78544923 |
| 84 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.76142179 |
| 85 | hydrogen ion transmembrane transport (GO:1902600) | 2.74415157 |
| 86 | resolution of meiotic recombination intermediates (GO:0000712) | 2.74293505 |
| 87 | parturition (GO:0007567) | 2.70778181 |
| 88 | L-fucose catabolic process (GO:0042355) | 2.66699406 |
| 89 | fucose catabolic process (GO:0019317) | 2.66699406 |
| 90 | L-fucose metabolic process (GO:0042354) | 2.66699406 |
| 91 | ATP biosynthetic process (GO:0006754) | 2.65755085 |
| 92 | replication fork processing (GO:0031297) | 2.65059633 |
| 93 | regulation of cilium movement (GO:0003352) | 2.65012249 |
| 94 | respiratory chain complex IV assembly (GO:0008535) | 2.62998550 |
| 95 | proton transport (GO:0015992) | 2.61816127 |
| 96 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.59674900 |
| 97 | positive regulation of prostaglandin secretion (GO:0032308) | 2.59505261 |
| 98 | regulation of action potential (GO:0098900) | 2.58115274 |
| 99 | segment specification (GO:0007379) | 2.58000163 |
| 100 | positive regulation of fatty acid transport (GO:2000193) | 2.57864487 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.88486508 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.82132111 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.45351732 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.06153092 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.97738284 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.87410627 |
| 7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.77783399 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.65517792 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.61183960 |
| 10 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.38998814 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.29958972 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.25202037 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.07991364 |
| 14 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.92808826 |
| 15 | VDR_22108803_ChIP-Seq_LS180_Human | 1.68631861 |
| 16 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.66906029 |
| 17 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.62601446 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.57136774 |
| 19 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.57045565 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.56637081 |
| 21 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.53781679 |
| 22 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.52489946 |
| 23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.52076033 |
| 24 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.50705916 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.50662002 |
| 26 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.49630082 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.48931542 |
| 28 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.46667746 |
| 29 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.46357147 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.45173278 |
| 31 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.43853412 |
| 32 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.43681581 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.43095917 |
| 34 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.41896534 |
| 35 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.40911274 |
| 36 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.38575389 |
| 37 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.37625401 |
| 38 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.37371615 |
| 39 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.36135737 |
| 40 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.35207890 |
| 41 | ERA_21632823_ChIP-Seq_H3396_Human | 1.32906252 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32636481 |
| 43 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.32532939 |
| 44 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30442479 |
| 45 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.29776822 |
| 46 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.29020588 |
| 47 | FUS_26573619_Chip-Seq_HEK293_Human | 1.23576223 |
| 48 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23205611 |
| 49 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.22501531 |
| 50 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.19774679 |
| 51 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.18910739 |
| 52 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.18529531 |
| 53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.17843553 |
| 54 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.17727433 |
| 55 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.17214247 |
| 56 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.15329107 |
| 57 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.13840726 |
| 58 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.13602714 |
| 59 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.13499576 |
| 60 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.12651169 |
| 61 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.10948356 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.10681696 |
| 63 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.10376394 |
| 64 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.10233496 |
| 65 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.09218519 |
| 66 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.08999224 |
| 67 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.08822924 |
| 68 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.08334982 |
| 69 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.08268466 |
| 70 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.07964783 |
| 71 | SA1_27219007_Chip-Seq_Bcells_Human | 1.06471630 |
| 72 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.05336440 |
| 73 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.03933784 |
| 74 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.03477562 |
| 75 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02040418 |
| 76 | AR_20517297_ChIP-Seq_VCAP_Human | 1.01898286 |
| 77 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.01659478 |
| 78 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.01542680 |
| 79 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.01268382 |
| 80 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99292141 |
| 81 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98799917 |
| 82 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.98777130 |
| 83 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.98172024 |
| 84 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.95926469 |
| 85 | EWS_26573619_Chip-Seq_HEK293_Human | 0.95528155 |
| 86 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.95439615 |
| 87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.94277195 |
| 88 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.93543173 |
| 89 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.93395394 |
| 90 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93005379 |
| 91 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93005379 |
| 92 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.92745207 |
| 93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.91468362 |
| 94 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.90272692 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87495344 |
| 96 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.86999374 |
| 97 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.86999374 |
| 98 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 0.86948546 |
| 99 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.85758187 |
| 100 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.84131786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.58896965 |
| 2 | MP0003787_abnormal_imprinting | 4.42107627 |
| 3 | MP0009379_abnormal_foot_pigmentation | 4.32694212 |
| 4 | MP0008877_abnormal_DNA_methylation | 4.04838581 |
| 5 | MP0003122_maternal_imprinting | 3.52694276 |
| 6 | MP0001348_abnormal_lacrimal_gland | 2.82312689 |
| 7 | MP0003123_paternal_imprinting | 2.62208371 |
| 8 | MP0003121_genomic_imprinting | 2.54060536 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.45745112 |
| 10 | MP0005377_hearing/vestibular/ear_phenot | 2.43121057 |
| 11 | MP0003878_abnormal_ear_physiology | 2.43121057 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.36885349 |
| 13 | MP0002653_abnormal_ependyma_morphology | 2.22091726 |
| 14 | MP0006276_abnormal_autonomic_nervous | 2.07816138 |
| 15 | MP0000569_abnormal_digit_pigmentation | 2.02201017 |
| 16 | MP0002822_catalepsy | 1.97658345 |
| 17 | MP0001293_anophthalmia | 1.97118705 |
| 18 | MP0008789_abnormal_olfactory_epithelium | 1.94706232 |
| 19 | MP0002102_abnormal_ear_morphology | 1.91340679 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.89412489 |
| 21 | MP0003646_muscle_fatigue | 1.83252489 |
| 22 | MP0004142_abnormal_muscle_tone | 1.79487813 |
| 23 | MP0004885_abnormal_endolymph | 1.77233069 |
| 24 | MP0000778_abnormal_nervous_system | 1.68046638 |
| 25 | MP0008872_abnormal_physiological_respon | 1.63403523 |
| 26 | MP0002837_dystrophic_cardiac_calcinosis | 1.62555321 |
| 27 | MP0005394_taste/olfaction_phenotype | 1.55414027 |
| 28 | MP0005499_abnormal_olfactory_system | 1.55414027 |
| 29 | MP0004742_abnormal_vestibular_system | 1.54614221 |
| 30 | MP0000049_abnormal_middle_ear | 1.50553446 |
| 31 | MP0002163_abnormal_gland_morphology | 1.47457003 |
| 32 | MP0000566_synostosis | 1.45318698 |
| 33 | MP0002272_abnormal_nervous_system | 1.36576948 |
| 34 | MP0002557_abnormal_social/conspecific_i | 1.33851374 |
| 35 | MP0001485_abnormal_pinna_reflex | 1.25792564 |
| 36 | MP0005551_abnormal_eye_electrophysiolog | 1.24970333 |
| 37 | MP0004133_heterotaxia | 1.24671397 |
| 38 | MP0001529_abnormal_vocalization | 1.24115172 |
| 39 | MP0005423_abnormal_somatic_nervous | 1.21860333 |
| 40 | MP0003880_abnormal_central_pattern | 1.21837836 |
| 41 | MP0001968_abnormal_touch/_nociception | 1.19412740 |
| 42 | MP0009745_abnormal_behavioral_response | 1.17762120 |
| 43 | MP0002938_white_spotting | 1.16933495 |
| 44 | MP0000631_abnormal_neuroendocrine_gland | 1.15922942 |
| 45 | MP0005646_abnormal_pituitary_gland | 1.14019861 |
| 46 | MP0001986_abnormal_taste_sensitivity | 1.12971333 |
| 47 | MP0000372_irregular_coat_pigmentation | 1.12170014 |
| 48 | MP0005195_abnormal_posterior_eye | 1.12147744 |
| 49 | MP0003186_abnormal_redox_activity | 1.11314982 |
| 50 | MP0001984_abnormal_olfaction | 1.10900556 |
| 51 | MP0002733_abnormal_thermal_nociception | 1.09468537 |
| 52 | MP0002160_abnormal_reproductive_system | 1.09218985 |
| 53 | MP0003879_abnormal_hair_cell | 1.08580215 |
| 54 | MP0001873_stomach_inflammation | 1.07976296 |
| 55 | MP0001905_abnormal_dopamine_level | 1.07550313 |
| 56 | MP0010030_abnormal_orbit_morphology | 1.05046720 |
| 57 | MP0005389_reproductive_system_phenotype | 1.03881917 |
| 58 | MP0000026_abnormal_inner_ear | 1.02891115 |
| 59 | MP0001486_abnormal_startle_reflex | 1.02808982 |
| 60 | MP0001970_abnormal_pain_threshold | 1.01291472 |
| 61 | MP0000427_abnormal_hair_cycle | 1.00315047 |
| 62 | MP0002736_abnormal_nociception_after | 0.98528674 |
| 63 | MP0002638_abnormal_pupillary_reflex | 0.95434703 |
| 64 | MP0004147_increased_porphyrin_level | 0.94415293 |
| 65 | MP0001963_abnormal_hearing_physiology | 0.92022855 |
| 66 | MP0005174_abnormal_tail_pigmentation | 0.91750842 |
| 67 | MP0005408_hypopigmentation | 0.91647567 |
| 68 | MP0002752_abnormal_somatic_nervous | 0.90262062 |
| 69 | MP0002063_abnormal_learning/memory/cond | 0.89002344 |
| 70 | MP0001919_abnormal_reproductive_system | 0.88955365 |
| 71 | MP0002572_abnormal_emotion/affect_behav | 0.87850502 |
| 72 | MP0002234_abnormal_pharynx_morphology | 0.87847832 |
| 73 | MP0009046_muscle_twitch | 0.84778848 |
| 74 | MP0003195_calcinosis | 0.84719242 |
| 75 | MP0002095_abnormal_skin_pigmentation | 0.84546378 |
| 76 | MP0005075_abnormal_melanosome_morpholog | 0.84539596 |
| 77 | MP0001440_abnormal_grooming_behavior | 0.84328187 |
| 78 | MP0002735_abnormal_chemical_nociception | 0.84138525 |
| 79 | MP0000230_abnormal_systemic_arterial | 0.83822154 |
| 80 | MP0002184_abnormal_innervation | 0.82525558 |
| 81 | MP0003011_delayed_dark_adaptation | 0.81185459 |
| 82 | MP0003937_abnormal_limbs/digits/tail_de | 0.80557015 |
| 83 | MP0005253_abnormal_eye_physiology | 0.78995115 |
| 84 | MP0003635_abnormal_synaptic_transmissio | 0.77981363 |
| 85 | MP0002876_abnormal_thyroid_physiology | 0.77383186 |
| 86 | MP0002064_seizures | 0.77024376 |
| 87 | MP0003942_abnormal_urinary_system | 0.76600186 |
| 88 | MP0000955_abnormal_spinal_cord | 0.74863979 |
| 89 | MP0008775_abnormal_heart_ventricle | 0.74202443 |
| 90 | MP0002210_abnormal_sex_determination | 0.73125133 |
| 91 | MP0002067_abnormal_sensory_capabilities | 0.73085919 |
| 92 | MP0001286_abnormal_eye_development | 0.71786559 |
| 93 | MP0002882_abnormal_neuron_morphology | 0.71196496 |
| 94 | MP0005386_behavior/neurological_phenoty | 0.71125089 |
| 95 | MP0004924_abnormal_behavior | 0.71125089 |
| 96 | MP0003938_abnormal_ear_development | 0.69023152 |
| 97 | MP0003136_yellow_coat_color | 0.67557908 |
| 98 | MP0002734_abnormal_mechanical_nocicepti | 0.67173351 |
| 99 | MP0001663_abnormal_digestive_system | 0.66648525 |
| 100 | MP0002229_neurodegeneration | 0.64454154 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 6.12622971 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.39766604 |
| 3 | Molar tooth sign on MRI (HP:0002419) | 4.26560951 |
| 4 | Abnormality of midbrain morphology (HP:0002418) | 4.26560951 |
| 5 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.79744676 |
| 6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.72981597 |
| 7 | Absent/shortened dynein arms (HP:0200106) | 3.72981597 |
| 8 | Septo-optic dysplasia (HP:0100842) | 3.68132762 |
| 9 | Macrocytic anemia (HP:0001972) | 3.33456648 |
| 10 | Abnormal number of erythroid precursors (HP:0012131) | 3.28050880 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.23342776 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.20140354 |
| 13 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.16717043 |
| 14 | Nephronophthisis (HP:0000090) | 3.13297906 |
| 15 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.09872104 |
| 16 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.09872104 |
| 17 | Acute necrotizing encephalopathy (HP:0006965) | 3.07530233 |
| 18 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.00251095 |
| 19 | Colon cancer (HP:0003003) | 2.98645085 |
| 20 | Mitochondrial inheritance (HP:0001427) | 2.97727441 |
| 21 | Asplenia (HP:0001746) | 2.95251718 |
| 22 | Pancreatic cysts (HP:0001737) | 2.93734288 |
| 23 | Type II lissencephaly (HP:0007260) | 2.89636856 |
| 24 | Papilledema (HP:0001085) | 2.87132539 |
| 25 | Pendular nystagmus (HP:0012043) | 2.80757328 |
| 26 | Congenital stationary night blindness (HP:0007642) | 2.79931514 |
| 27 | Increased CSF lactate (HP:0002490) | 2.79186325 |
| 28 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.76149953 |
| 29 | True hermaphroditism (HP:0010459) | 2.70154457 |
| 30 | Acute encephalopathy (HP:0006846) | 2.68904655 |
| 31 | Stenosis of the external auditory canal (HP:0000402) | 2.56473127 |
| 32 | Abnormal ciliary motility (HP:0012262) | 2.54964621 |
| 33 | Medial flaring of the eyebrow (HP:0010747) | 2.53693704 |
| 34 | Abnormal biliary tract physiology (HP:0012439) | 2.49881865 |
| 35 | Bile duct proliferation (HP:0001408) | 2.49881865 |
| 36 | Rib fusion (HP:0000902) | 2.48008514 |
| 37 | Thyroid-stimulating hormone excess (HP:0002925) | 2.47546444 |
| 38 | Abnormality of the labia minora (HP:0012880) | 2.46473028 |
| 39 | Abnormality of the renal medulla (HP:0100957) | 2.45244094 |
| 40 | Pallor (HP:0000980) | 2.44753126 |
| 41 | Optic nerve hypoplasia (HP:0000609) | 2.44676234 |
| 42 | Hepatocellular necrosis (HP:0001404) | 2.44503889 |
| 43 | Supernumerary spleens (HP:0009799) | 2.42976844 |
| 44 | Chronic hepatic failure (HP:0100626) | 2.37455989 |
| 45 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.35531028 |
| 46 | Progressive macrocephaly (HP:0004481) | 2.34286115 |
| 47 | Absent thumb (HP:0009777) | 2.32958294 |
| 48 | Stomatitis (HP:0010280) | 2.25647965 |
| 49 | Sclerocornea (HP:0000647) | 2.24969885 |
| 50 | Growth hormone deficiency (HP:0000824) | 2.24302035 |
| 51 | Lissencephaly (HP:0001339) | 2.21918677 |
| 52 | Hyperglycinemia (HP:0002154) | 2.17512917 |
| 53 | Optic disc pallor (HP:0000543) | 2.16930637 |
| 54 | Polydipsia (HP:0001959) | 2.13704059 |
| 55 | Abnormal drinking behavior (HP:0030082) | 2.13704059 |
| 56 | Absent septum pellucidum (HP:0001331) | 2.12570621 |
| 57 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.11703721 |
| 58 | Hepatic necrosis (HP:0002605) | 2.09948974 |
| 59 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.09527997 |
| 60 | Maternal diabetes (HP:0009800) | 2.09447596 |
| 61 | Hypoplasia of the ulna (HP:0003022) | 2.07189604 |
| 62 | Abolished electroretinogram (ERG) (HP:0000550) | 2.05781627 |
| 63 | Oligodactyly (hands) (HP:0001180) | 2.05039306 |
| 64 | Cystic liver disease (HP:0006706) | 2.04810199 |
| 65 | Oligodactyly (HP:0012165) | 2.04653276 |
| 66 | Lipid accumulation in hepatocytes (HP:0006561) | 2.02999211 |
| 67 | Inability to walk (HP:0002540) | 2.02124753 |
| 68 | Increased serum lactate (HP:0002151) | 2.01279248 |
| 69 | Polyphagia (HP:0002591) | 2.01125285 |
| 70 | High anterior hairline (HP:0009890) | 2.00663228 |
| 71 | Depressed nasal ridge (HP:0000457) | 2.00165050 |
| 72 | Adrenal hypoplasia (HP:0000835) | 1.97136928 |
| 73 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.96310865 |
| 74 | Increased corneal curvature (HP:0100692) | 1.96274184 |
| 75 | Keratoconus (HP:0000563) | 1.96274184 |
| 76 | Anencephaly (HP:0002323) | 1.95691507 |
| 77 | Hip dysplasia (HP:0001385) | 1.92800020 |
| 78 | Abnormality of the 4th metacarpal (HP:0010012) | 1.89582150 |
| 79 | Postaxial foot polydactyly (HP:0001830) | 1.88205446 |
| 80 | Increased hepatocellular lipid droplets (HP:0006565) | 1.86800118 |
| 81 | Ketosis (HP:0001946) | 1.85084796 |
| 82 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.84680149 |
| 83 | Cerebellar dysplasia (HP:0007033) | 1.83889918 |
| 84 | Pachygyria (HP:0001302) | 1.81845753 |
| 85 | Cerebral edema (HP:0002181) | 1.81629835 |
| 86 | Abnormality of reticulocytes (HP:0004312) | 1.81576776 |
| 87 | Hypoplasia of the radius (HP:0002984) | 1.81300169 |
| 88 | Gait imbalance (HP:0002141) | 1.81159165 |
| 89 | Lactic acidosis (HP:0003128) | 1.78657559 |
| 90 | Congenital primary aphakia (HP:0007707) | 1.77861928 |
| 91 | Nephrogenic diabetes insipidus (HP:0009806) | 1.77730185 |
| 92 | Increased intramyocellular lipid droplets (HP:0012240) | 1.77622873 |
| 93 | Forearm undergrowth (HP:0009821) | 1.77033062 |
| 94 | Progressive cerebellar ataxia (HP:0002073) | 1.75042736 |
| 95 | Horseshoe kidney (HP:0000085) | 1.72595246 |
| 96 | Delayed CNS myelination (HP:0002188) | 1.70933501 |
| 97 | Preaxial hand polydactyly (HP:0001177) | 1.70423620 |
| 98 | Abnormal hemoglobin (HP:0011902) | 1.69459380 |
| 99 | 3-Methylglutaconic aciduria (HP:0003535) | 1.69245311 |
| 100 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.68825965 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EPHB2 | 3.74349574 |
| 2 | PINK1 | 3.55163507 |
| 3 | ZAK | 3.22453811 |
| 4 | MAP4K2 | 3.04270729 |
| 5 | DYRK2 | 2.53004272 |
| 6 | WNK4 | 2.51993810 |
| 7 | VRK2 | 2.50425289 |
| 8 | STK16 | 2.44668561 |
| 9 | BCKDK | 2.28581771 |
| 10 | MAPKAPK3 | 2.25200549 |
| 11 | TXK | 2.07030601 |
| 12 | TLK1 | 1.78662871 |
| 13 | WNK3 | 1.75314375 |
| 14 | GRK1 | 1.71675819 |
| 15 | ADRBK2 | 1.69228424 |
| 16 | MAP3K12 | 1.62165934 |
| 17 | LRRK2 | 1.61645924 |
| 18 | EEF2K | 1.57648143 |
| 19 | CDK8 | 1.56097088 |
| 20 | MAP2K2 | 1.50599347 |
| 21 | MAPK13 | 1.49952840 |
| 22 | MAPKAPK5 | 1.43441049 |
| 23 | BMPR1B | 1.38718005 |
| 24 | TYRO3 | 1.38601363 |
| 25 | STK39 | 1.38496477 |
| 26 | PLK4 | 1.31383559 |
| 27 | MAP3K11 | 1.31339427 |
| 28 | VRK1 | 1.31335471 |
| 29 | CDC7 | 1.29296514 |
| 30 | TIE1 | 1.27533297 |
| 31 | TAOK3 | 1.25650196 |
| 32 | NTRK2 | 1.21509189 |
| 33 | NUAK1 | 1.21289458 |
| 34 | CAMKK2 | 1.20157184 |
| 35 | NME1 | 1.18248985 |
| 36 | LIMK1 | 1.16853969 |
| 37 | PBK | 1.15960874 |
| 38 | TNK2 | 1.13752178 |
| 39 | RPS6KB2 | 1.08550582 |
| 40 | NTRK1 | 1.07241047 |
| 41 | MATK | 1.00498684 |
| 42 | CAMK1 | 0.99899751 |
| 43 | STK11 | 0.98095360 |
| 44 | TGFBR1 | 0.94656439 |
| 45 | FRK | 0.93715702 |
| 46 | OXSR1 | 0.92096094 |
| 47 | PRKCG | 0.90519096 |
| 48 | EPHA4 | 0.88108918 |
| 49 | MKNK2 | 0.85594260 |
| 50 | TRIM28 | 0.84385251 |
| 51 | EIF2AK1 | 0.82911894 |
| 52 | DMPK | 0.82269844 |
| 53 | CDK19 | 0.80061445 |
| 54 | DAPK3 | 0.77851644 |
| 55 | PLK2 | 0.77322371 |
| 56 | PAK6 | 0.75373953 |
| 57 | CAMK1G | 0.74290690 |
| 58 | RPS6KA5 | 0.74078700 |
| 59 | PASK | 0.73750997 |
| 60 | AURKA | 0.72348648 |
| 61 | CAMK1D | 0.69842167 |
| 62 | DYRK1B | 0.69512277 |
| 63 | PNCK | 0.62714819 |
| 64 | TNIK | 0.61927821 |
| 65 | BRD4 | 0.61857776 |
| 66 | PRKCQ | 0.60728423 |
| 67 | PIK3CA | 0.60065990 |
| 68 | AURKB | 0.58534015 |
| 69 | PAK3 | 0.58503276 |
| 70 | GRK5 | 0.58453203 |
| 71 | BCR | 0.56645583 |
| 72 | KIT | 0.55980756 |
| 73 | PRKCI | 0.54925217 |
| 74 | PRKACA | 0.53615750 |
| 75 | PIK3CG | 0.52786632 |
| 76 | CHEK2 | 0.52160330 |
| 77 | KDR | 0.50646971 |
| 78 | MAP3K4 | 0.48645192 |
| 79 | RPS6KA2 | 0.48021187 |
| 80 | RPS6KA6 | 0.47028299 |
| 81 | PLK3 | 0.45718426 |
| 82 | DAPK2 | 0.44849158 |
| 83 | PDK2 | 0.44175330 |
| 84 | INSRR | 0.43643141 |
| 85 | ADRBK1 | 0.42531859 |
| 86 | MAP2K7 | 0.40059911 |
| 87 | PRKCZ | 0.39932588 |
| 88 | MAPK15 | 0.39555776 |
| 89 | LCK | 0.39046301 |
| 90 | MAP2K4 | 0.35887422 |
| 91 | RPS6KA1 | 0.35097885 |
| 92 | PTK2B | 0.34229013 |
| 93 | IKBKB | 0.33995776 |
| 94 | PLK1 | 0.33536536 |
| 95 | NTRK3 | 0.32671042 |
| 96 | TESK2 | 0.31758145 |
| 97 | SGK223 | 0.31453090 |
| 98 | SGK494 | 0.31453090 |
| 99 | EPHA3 | 0.31194482 |
| 100 | ILK | 0.31159794 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.03499886 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.15825687 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.33050587 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 2.62427695 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.44350983 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.43176469 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.39570650 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.37107466 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.32916370 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.29286687 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.27691968 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 2.23855513 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.18020031 |
| 14 | Sulfur relay system_Homo sapiens_hsa04122 | 2.14975747 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.08823854 |
| 16 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.86812607 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.78437727 |
| 18 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.72851219 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.67462261 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.63313382 |
| 21 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.57508698 |
| 22 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.54241532 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.52633434 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.47635933 |
| 25 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.44930722 |
| 26 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.34541262 |
| 27 | Allograft rejection_Homo sapiens_hsa05330 | 1.34039779 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.25725579 |
| 29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.21683265 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.16558105 |
| 31 | Basal transcription factors_Homo sapiens_hsa03022 | 1.11582429 |
| 32 | Nicotine addiction_Homo sapiens_hsa05033 | 1.11078708 |
| 33 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.08229930 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 1.07908779 |
| 35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.03008610 |
| 36 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.98048073 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97370702 |
| 38 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.96022023 |
| 39 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.94355868 |
| 40 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.85859293 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85735090 |
| 42 | Spliceosome_Homo sapiens_hsa03040 | 0.85334617 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.82236965 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81624504 |
| 45 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.80761132 |
| 46 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.80631917 |
| 47 | DNA replication_Homo sapiens_hsa03030 | 0.80043982 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.79218008 |
| 49 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.79001259 |
| 50 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78938421 |
| 51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.76753648 |
| 52 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.76312877 |
| 53 | Mismatch repair_Homo sapiens_hsa03430 | 0.74748832 |
| 54 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.74008781 |
| 55 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.72235945 |
| 56 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.72080951 |
| 57 | Morphine addiction_Homo sapiens_hsa05032 | 0.68259821 |
| 58 | Base excision repair_Homo sapiens_hsa03410 | 0.68038652 |
| 59 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.67552465 |
| 60 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.65235747 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64610278 |
| 62 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.64050737 |
| 63 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.63767430 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.62571496 |
| 65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62163014 |
| 66 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60714503 |
| 67 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.59195690 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57456160 |
| 69 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.57374472 |
| 70 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.57133120 |
| 71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51707682 |
| 72 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.51477739 |
| 73 | Insulin secretion_Homo sapiens_hsa04911 | 0.51138408 |
| 74 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.50885275 |
| 75 | Purine metabolism_Homo sapiens_hsa00230 | 0.49638090 |
| 76 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.42568728 |
| 77 | Olfactory transduction_Homo sapiens_hsa04740 | 0.42096527 |
| 78 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.40874441 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38681367 |
| 80 | Axon guidance_Homo sapiens_hsa04360 | 0.37960526 |
| 81 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.36606129 |
| 82 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.35735071 |
| 83 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.35345573 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.34959227 |
| 85 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.34305307 |
| 86 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.33900802 |
| 87 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.32383236 |
| 88 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.32247340 |
| 89 | GABAergic synapse_Homo sapiens_hsa04727 | 0.30322962 |
| 90 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.28139012 |
| 91 | Salivary secretion_Homo sapiens_hsa04970 | 0.27615213 |
| 92 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.27061988 |
| 93 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26631608 |
| 94 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.25878448 |
| 95 | Circadian entrainment_Homo sapiens_hsa04713 | 0.25553941 |
| 96 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.25427844 |
| 97 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.24282159 |
| 98 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.23032315 |
| 99 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.21479411 |
| 100 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.21354479 |

