RPS27P29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1glyoxylate metabolic process (GO:0046487)9.89549090
2establishment of protein localization to mitochondrial membrane (GO:0090151)9.85922733
3ectoderm development (GO:0007398)8.84499363
4female gonad development (GO:0008585)6.72606878
5inner mitochondrial membrane organization (GO:0007007)6.65823310
6regulation of telomere maintenance via telomerase (GO:0032210)6.51570039
7negative regulation of telomere maintenance (GO:0032205)6.48295826
8male meiosis (GO:0007140)5.75012747
9thyroid hormone generation (GO:0006590)5.66818461
10cranial suture morphogenesis (GO:0060363)5.03746341
11negative regulation of glycoprotein biosynthetic process (GO:0010561)4.95785780
12central nervous system neuron axonogenesis (GO:0021955)4.82514819
13regulation of protein glycosylation (GO:0060049)4.79035643
14cellular response to hepatocyte growth factor stimulus (GO:0035729)4.78043028
15response to hepatocyte growth factor (GO:0035728)4.78043028
16stress granule assembly (GO:0034063)4.75625979
17thyroid hormone metabolic process (GO:0042403)4.73524486
18regulation of natural killer cell mediated immunity (GO:0002715)4.71553005
19regulation of natural killer cell mediated cytotoxicity (GO:0042269)4.71553005
20regulation of G0 to G1 transition (GO:0070316)4.68416084
21positive regulation of keratinocyte differentiation (GO:0045618)4.67350945
22mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.62326287
23apoptotic DNA fragmentation (GO:0006309)4.61440751
24negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)4.56972012
25viral transcription (GO:0019083)4.49611868
26DNA strand renaturation (GO:0000733)4.26007835
27viral protein processing (GO:0019082)4.23235204
28protein-cofactor linkage (GO:0018065)4.22689135
29energy coupled proton transport, down electrochemical gradient (GO:0015985)4.21135983
30ATP synthesis coupled proton transport (GO:0015986)4.21135983
31regulation of antigen processing and presentation of peptide antigen (GO:0002583)4.17458905
32mast cell activation (GO:0045576)4.16324539
33somatic hypermutation of immunoglobulin genes (GO:0016446)4.14010100
34somatic diversification of immune receptors via somatic mutation (GO:0002566)4.14010100
35translational termination (GO:0006415)4.09275827
36ventricular trabecula myocardium morphogenesis (GO:0003222)4.08334294
37cellular response to thyroid hormone stimulus (GO:0097067)3.92903488
38peptidyl-lysine dimethylation (GO:0018027)3.91361135
39intermediate filament cytoskeleton organization (GO:0045104)3.89751883
40phospholipid translocation (GO:0045332)3.82309106
41lipid translocation (GO:0034204)3.82309106
42intermediate filament-based process (GO:0045103)3.81551029
43hydrogen peroxide biosynthetic process (GO:0050665)3.80727843
44ribosomal small subunit assembly (GO:0000028)3.77104880
45negative regulation of glycoprotein metabolic process (GO:1903019)3.69385738
46natural killer cell activation (GO:0030101)3.66833824
47SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.60724135
48viral life cycle (GO:0019058)3.59668726
49cotranslational protein targeting to membrane (GO:0006613)3.59293516
50centrosome duplication (GO:0051298)3.59123976
51heart trabecula morphogenesis (GO:0061384)3.56980894
52intracellular protein transmembrane import (GO:0044743)3.56181394
53protein targeting to ER (GO:0045047)3.54980376
54maintenance of protein location in nucleus (GO:0051457)3.48446127
55mitotic G2 DNA damage checkpoint (GO:0007095)3.48207282
56reactive oxygen species biosynthetic process (GO:1903409)3.45015863
57ribosomal small subunit biogenesis (GO:0042274)3.43219906
58establishment of protein localization to endoplasmic reticulum (GO:0072599)3.35831213
59protein localization to endoplasmic reticulum (GO:0070972)3.35793245
60negative regulation of protein tyrosine kinase activity (GO:0061099)3.33914005
61translational elongation (GO:0006414)3.33262042
62cellular protein complex disassembly (GO:0043624)3.30126416
63galactose metabolic process (GO:0006012)3.26710907
64regulation of leukocyte mediated cytotoxicity (GO:0001910)3.25274301
65regulation of telomere maintenance (GO:0032204)3.24296734
66parturition (GO:0007567)3.23354578
67regulation of sister chromatid cohesion (GO:0007063)3.20318317
68RNA destabilization (GO:0050779)3.15725661
69positive regulation of transcription regulatory region DNA binding (GO:2000679)3.15580746
70SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146)3.08002410
71regulation of interferon-beta biosynthetic process (GO:0045357)3.05955868
72positive regulation of epidermal cell differentiation (GO:0045606)3.05477924
73positive regulation of fatty acid beta-oxidation (GO:0032000)3.03583713
74superoxide anion generation (GO:0042554)3.00747042
75nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.99779389
76negative regulation of keratinocyte proliferation (GO:0010839)2.97205656
77regulation of histone phosphorylation (GO:0033127)2.97134739
78trabecula morphogenesis (GO:0061383)2.96138142
79negative regulation of receptor activity (GO:2000272)2.95700264
80regulation of rhodopsin mediated signaling pathway (GO:0022400)2.94414118
81middle ear morphogenesis (GO:0042474)2.92576368
82cellular response to interleukin-15 (GO:0071350)2.91790302
83negative regulation of fatty acid biosynthetic process (GO:0045717)2.89346800
84behavioral response to nicotine (GO:0035095)2.88932064
85vitamin transmembrane transport (GO:0035461)2.83367732
86regulation of cell killing (GO:0031341)2.82966610
87mitotic G2/M transition checkpoint (GO:0044818)2.74593352
88replication fork processing (GO:0031297)2.74352185
89signal peptide processing (GO:0006465)2.73151845
90androgen biosynthetic process (GO:0006702)2.73072148
91craniofacial suture morphogenesis (GO:0097094)2.72907748
92maturation of SSU-rRNA (GO:0030490)2.71709643
93rhodopsin mediated signaling pathway (GO:0016056)2.66398169
94response to thyroid hormone (GO:0097066)2.66005575
95cellular ketone body metabolic process (GO:0046950)2.65441229
96fatty acid transmembrane transport (GO:1902001)2.64665729
97regulation of isotype switching to IgG isotypes (GO:0048302)2.63754836
98neurofilament cytoskeleton organization (GO:0060052)15.0142975
99regulation of DNA methylation (GO:0044030)11.4968060
100chaperone-mediated protein transport (GO:0072321)10.2365148

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse5.36266135
2IGF1R_20145208_ChIP-Seq_DFB_Human4.57388218
3IRF1_19129219_ChIP-ChIP_H3396_Human4.33345945
4VDR_22108803_ChIP-Seq_LS180_Human4.22265262
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.84143076
6BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.74566587
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.71368056
8EZH2_22144423_ChIP-Seq_EOC_Human2.48337228
9ZNF274_21170338_ChIP-Seq_K562_Hela2.45968715
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.44784919
11VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.00126187
12AUTS2_25519132_ChIP-Seq_293T-REX_Human1.96555474
13SALL1_21062744_ChIP-ChIP_HESCs_Human1.94499523
14GBX2_23144817_ChIP-Seq_PC3_Human1.89341933
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.80717270
16LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.80708086
17TP53_22573176_ChIP-Seq_HFKS_Human1.73202143
18RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.61738397
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.48020955
20ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.47550076
21CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.44306276
22EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.40794683
23TDRD3_21172665_ChIP-Seq_MCF-7_Human1.40494910
24PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.39497844
25KAP1_22055183_ChIP-Seq_ESCs_Mouse1.38618911
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.37067938
27IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.36625098
28CBP_20019798_ChIP-Seq_JUKART_Human1.36625098
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.36599440
30PIAS1_25552417_ChIP-Seq_VCAP_Human1.35664051
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.32291907
32BP1_19119308_ChIP-ChIP_Hs578T_Human1.31944060
33SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.31203436
34CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.30675862
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.29251273
36CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.28568618
37YY1_21170310_ChIP-Seq_MESCs_Mouse1.28453092
38AR_21572438_ChIP-Seq_LNCaP_Human1.28040927
39ELK1_22589737_ChIP-Seq_MCF10A_Human1.27569029
40RUNX_20019798_ChIP-Seq_JUKART_Human1.26793634
41JARID2_20064375_ChIP-Seq_MESCs_Mouse1.19812199
42STAT4_19710469_ChIP-ChIP_TH1__Mouse1.19490950
43ETS1_20019798_ChIP-Seq_JURKAT_Human1.19419047
44NANOG_20526341_ChIP-Seq_ESCs_Human1.18090465
45TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.15932833
46GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.15029557
47MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.13005234
48SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.10620892
49JARID2_20075857_ChIP-Seq_MESCs_Mouse1.09673941
50PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.09378130
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.08687955
52VDR_24787735_ChIP-Seq_THP-1_Human1.07546841
53IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.07378986
54CTBP2_25329375_ChIP-Seq_LNCAP_Human1.06744474
55ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.06011645
56FOXH1_21741376_ChIP-Seq_ESCs_Human1.05866054
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.03851699
58PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03411678
59TAF2_19829295_ChIP-Seq_ESCs_Human1.01661668
60HTT_18923047_ChIP-ChIP_STHdh_Human1.00509967
61JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.99135949
62SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.98332568
63NCOR_22424771_ChIP-Seq_293T_Human0.96012910
64PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.94347431
65GATA3_21878914_ChIP-Seq_MCF-7_Human0.93742274
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.92306988
67EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.92165640
68STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.91676477
69CTBP1_25329375_ChIP-Seq_LNCAP_Human0.90897628
70CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.90246419
71PCGF2_27294783_Chip-Seq_ESCs_Mouse0.90020914
72FLI1_27457419_Chip-Seq_LIVER_Mouse0.88962626
73CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88336655
74LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.87865336
75EZH2_27294783_Chip-Seq_ESCs_Mouse0.87441096
76BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.85341342
77E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.84574701
78GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.83954880
79VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.82669456
80TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.82351719
81GATA3_27048872_Chip-Seq_THYMUS_Human0.81672011
82CIITA_25753668_ChIP-Seq_RAJI_Human0.81473496
83ELK1_19687146_ChIP-ChIP_HELA_Human0.81222666
84CBX2_27304074_Chip-Seq_ESCs_Mouse0.80263592
85UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.80228966
86SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78982067
87PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.78865534
88SUZ12_27294783_Chip-Seq_ESCs_Mouse0.78116799
89BCAT_22108803_ChIP-Seq_LS180_Human0.77530016
90NFE2_27457419_Chip-Seq_LIVER_Mouse0.76973573
91SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.76719738
92GATA6_21074721_ChIP-Seq_CACO-2_Human0.76428134
93GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.76253558
94GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse0.75663823
95RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.75434259
96EP300_21415370_ChIP-Seq_HL-1_Mouse0.75412816
97REST_21632747_ChIP-Seq_MESCs_Mouse0.75395667
98EZH2_27304074_Chip-Seq_ESCs_Mouse0.75099198
99ZFP57_27257070_Chip-Seq_ESCs_Mouse0.74622033
100VDR_21846776_ChIP-Seq_THP-1_Human0.74577209

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008995_early_reproductive_senescence9.21231488
2MP0002876_abnormal_thyroid_physiology4.18027775
3MP0005671_abnormal_response_to3.74864471
4MP0003786_premature_aging3.70265735
5MP0002653_abnormal_ependyma_morphology3.65923152
6MP0006082_CNS_inflammation2.95101940
7MP0001986_abnormal_taste_sensitivity2.66241040
8MP0004885_abnormal_endolymph2.54756969
9MP0008875_abnormal_xenobiotic_pharmacok2.54339906
10MP0003763_abnormal_thymus_physiology2.48860731
11MP0009379_abnormal_foot_pigmentation2.24001774
12MP0004264_abnormal_extraembryonic_tissu2.07844926
13MP0009785_altered_susceptibility_to1.83450098
14MP0004742_abnormal_vestibular_system1.83176039
15MP0006276_abnormal_autonomic_nervous1.73804306
16MP0005387_immune_system_phenotype1.73278308
17MP0001790_abnormal_immune_system1.73278308
18MP0005360_urolithiasis1.66863649
19MP0004019_abnormal_vitamin_homeostasis1.64897920
20MP0005025_abnormal_response_to1.60982000
21MP0002132_abnormal_respiratory_system1.58653267
22MP0009333_abnormal_splenocyte_physiolog1.50674911
23MP0002723_abnormal_immune_serum1.48060812
24MP0002420_abnormal_adaptive_immunity1.44858081
25MP0003646_muscle_fatigue1.44732613
26MP0001800_abnormal_humoral_immune1.42923095
27MP0010386_abnormal_urinary_bladder1.42642129
28MP0005085_abnormal_gallbladder_physiolo1.40731079
29MP0001849_ear_inflammation1.40360952
30MP0005000_abnormal_immune_tolerance1.39915985
31MP0001819_abnormal_immune_cell1.39861469
32MP0005377_hearing/vestibular/ear_phenot1.33541446
33MP0003878_abnormal_ear_physiology1.33541446
34MP0001485_abnormal_pinna_reflex1.29122047
35MP0002148_abnormal_hypersensitivity_rea1.28544388
36MP0003866_abnormal_defecation1.28252222
37MP0001835_abnormal_antigen_presentation1.21618847
38MP0010094_abnormal_chromosome_stability1.17866793
39MP0002127_abnormal_cardiovascular_syste1.17112321
40MP0003879_abnormal_hair_cell1.16689517
41MP0001119_abnormal_female_reproductive1.14274346
42MP0001440_abnormal_grooming_behavior1.11895018
43MP0006292_abnormal_olfactory_placode1.10229546
44MP0001666_abnormal_nutrient_absorption1.09467490
45MP0000716_abnormal_immune_system1.09156612
46MP0002398_abnormal_bone_marrow1.07910035
47MP0005551_abnormal_eye_electrophysiolog1.04107580
48MP0005084_abnormal_gallbladder_morpholo1.03172345
49MP0002452_abnormal_antigen_presenting1.03061342
50MP0003436_decreased_susceptibility_to1.02051684
51MP0003011_delayed_dark_adaptation1.00048302
52MP0003936_abnormal_reproductive_system0.96283716
53MP0000569_abnormal_digit_pigmentation0.91727009
54MP0001881_abnormal_mammary_gland0.90431929
55MP0002429_abnormal_blood_cell0.89295954
56MP0005645_abnormal_hypothalamus_physiol0.88293673
57MP0000343_altered_response_to0.88073601
58MP0004142_abnormal_muscle_tone0.88063723
59MP0002837_dystrophic_cardiac_calcinosis0.88029426
60MP0002638_abnormal_pupillary_reflex0.86716875
61MP0009046_muscle_twitch0.86382729
62MP0002163_abnormal_gland_morphology0.85556964
63MP0001542_abnormal_bone_strength0.81167768
64MP0008877_abnormal_DNA_methylation0.81136947
65MP0009764_decreased_sensitivity_to0.79514732
66MP0002138_abnormal_hepatobiliary_system0.79265473
67MP0005464_abnormal_platelet_physiology0.78132889
68MP0000604_amyloidosis0.75804033
69MP0008775_abnormal_heart_ventricle0.74988470
70MP0001919_abnormal_reproductive_system0.74935353
71MP0006072_abnormal_retinal_apoptosis0.74318805
72MP0003195_calcinosis0.74264549
73MP0003699_abnormal_female_reproductive0.73827288
74MP0008872_abnormal_physiological_respon0.73506150
75MP0001984_abnormal_olfaction0.73356330
76MP0002210_abnormal_sex_determination0.73113707
77MP0005646_abnormal_pituitary_gland0.72894184
78MP0002277_abnormal_respiratory_mucosa0.72389654
79MP0001845_abnormal_inflammatory_respons0.71865976
80MP0010155_abnormal_intestine_physiology0.71398896
81MP0002697_abnormal_eye_size0.70436131
82MP0002095_abnormal_skin_pigmentation0.69704653
83MP0000685_abnormal_immune_system0.68503566
84MP0003186_abnormal_redox_activity0.67523652
85MP0001905_abnormal_dopamine_level0.64816070
86MP0003632_abnormal_nervous_system0.64388368
87MP0005379_endocrine/exocrine_gland_phen0.63529359
88MP0005174_abnormal_tail_pigmentation0.63005267
89MP0010329_abnormal_lipoprotein_level0.62286735
90MP0002419_abnormal_innate_immunity0.61768060
91MP0002229_neurodegeneration0.61729209
92MP0002102_abnormal_ear_morphology0.61664803
93MP0002734_abnormal_mechanical_nocicepti0.60921360
94MP0003111_abnormal_nucleus_morphology0.60819479
95MP0005332_abnormal_amino_acid0.60501518
96MP0005389_reproductive_system_phenotype0.59360977
97MP0002405_respiratory_system_inflammati0.58358383
98MP0004947_skin_inflammation0.57388246
99MP0004270_analgesia0.57276013
100MP0001968_abnormal_touch/_nociception0.57233621

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)9.43506967
2Duplicated collecting system (HP:0000081)8.82188202
3Chromosomal breakage induced by crosslinking agents (HP:0003221)8.32139305
4Abnormality of the renal collecting system (HP:0004742)8.02731243
5Chromsome breakage (HP:0040012)7.29248175
6Abnormality of pyrimidine metabolism (HP:0004353)7.18559077
7Abnormality of DNA repair (HP:0003254)6.57875393
8Oral leukoplakia (HP:0002745)5.95115239
9Aplastic anemia (HP:0001915)5.89988933
10Autoimmune thrombocytopenia (HP:0001973)5.20932627
11Ureteral duplication (HP:0000073)5.19375440
12Duplication of thumb phalanx (HP:0009942)5.05938368
13Absent thumb (HP:0009777)4.46043027
14Ectopic kidney (HP:0000086)4.41556114
15Increased serum pyruvate (HP:0003542)4.39279105
16Abnormality of T cell number (HP:0011839)3.78566933
17Pancytopenia (HP:0001876)3.64916971
18Abnormality of B cell number (HP:0010975)3.61935629
19Aplasia/Hypoplasia of the uvula (HP:0010293)3.60542189
20Renal cortical cysts (HP:0000803)3.60354370
21Enlarged epiphyses (HP:0010580)3.55614113
22Abnormality of glycolysis (HP:0004366)3.50625612
23Autoimmune hemolytic anemia (HP:0001890)3.45944523
24Eosinophilia (HP:0001880)3.44610177
25Increased IgM level (HP:0003496)3.36775630
26Thyroid-stimulating hormone excess (HP:0002925)3.35097904
27Meckel diverticulum (HP:0002245)3.27670163
28Increased hepatocellular lipid droplets (HP:0006565)3.22239058
29Stomach cancer (HP:0012126)3.19907960
30Abnormality of the ileum (HP:0001549)3.19704059
31Abnormality of the preputium (HP:0100587)3.15906007
32Abnormality of T cells (HP:0002843)2.95031680
33Hypergonadotropic hypogonadism (HP:0000815)2.94486677
34Horseshoe kidney (HP:0000085)2.92970029
35Absent radius (HP:0003974)2.92068487
36Lipid accumulation in hepatocytes (HP:0006561)2.85509763
37Aplasia involving forearm bones (HP:0009822)2.81245674
38Absent forearm bone (HP:0003953)2.81245674
39Abnormality of eosinophils (HP:0001879)2.76701566
40Abnormality of reticulocytes (HP:0004312)2.74191271
41Clubbing of toes (HP:0100760)2.70836896
42Renal Fanconi syndrome (HP:0001994)2.66565873
43Granulocytopenia (HP:0001913)2.64571763
44Rough bone trabeculation (HP:0100670)2.59578757
45Neutropenia (HP:0001875)2.58548522
46Joint swelling (HP:0001386)2.55410466
47Abnormality of nucleobase metabolism (HP:0010932)2.54171103
48Abnormality of chromosome stability (HP:0003220)2.53973653
49T lymphocytopenia (HP:0005403)2.52344088
50Abnormal delayed hypersensitivity skin test (HP:0002963)2.49681633
51Pallor (HP:0000980)2.49285128
52Abnormality of the carotid arteries (HP:0005344)2.42091632
53Increased intramyocellular lipid droplets (HP:0012240)2.31874493
54Cellular immunodeficiency (HP:0005374)2.31825761
55Exertional dyspnea (HP:0002875)2.15244861
56Hypoplasia of the capital femoral epiphysis (HP:0003090)2.14300231
57Leukopenia (HP:0001882)2.13367760
58Abnormality of the renal cortex (HP:0011035)2.13247375
59Flattened epiphyses (HP:0003071)2.10870817
60Abnormality of the phalanges of the 2nd finger (HP:0009541)2.10005800
61Abnormality of the vertebral endplates (HP:0005106)2.07454930
62Prostate neoplasm (HP:0100787)2.06230980
63Partial duplication of the phalanx of hand (HP:0009999)2.06029092
64Bone marrow hypocellularity (HP:0005528)2.05615082
65Short thumb (HP:0009778)2.01962469
66Nausea (HP:0002018)2.00493074
67Duodenal stenosis (HP:0100867)1.96235502
68Small intestinal stenosis (HP:0012848)1.96235502
69Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.94856518
70Acute necrotizing encephalopathy (HP:0006965)1.94033635
71Abnormal trabecular bone morphology (HP:0100671)1.93227449
72Mutism (HP:0002300)1.90307669
73Increased muscle lipid content (HP:0009058)1.89421878
74Abnormality of urine glucose concentration (HP:0011016)1.87761591
75Glycosuria (HP:0003076)1.87761591
76Hypochromic anemia (HP:0001931)1.86729442
77Mitochondrial inheritance (HP:0001427)1.83882892
78Leukocytosis (HP:0001974)1.83747013
79Triphalangeal thumb (HP:0001199)1.83398119
80Abnormality of the epiphysis of the femoral head (HP:0010574)1.81416067
81Spinal cord lesions (HP:0100561)1.76224781
82Syringomyelia (HP:0003396)1.76224781
83Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.76124023
84Absent epiphyses (HP:0010577)1.76124023
85Tracheoesophageal fistula (HP:0002575)1.75182553
86Progressive neurologic deterioration (HP:0002344)1.74063539
87Renal agenesis (HP:0000104)1.69618340
88Abnormality of the femoral head (HP:0003368)1.68481154
89Abnormality of T cell physiology (HP:0011840)1.68071644
90Megalocornea (HP:0000485)1.67680749
91Abnormality of cells of the lymphoid lineage (HP:0012140)1.67433230
92Cerebral edema (HP:0002181)1.66099068
93Increased CSF lactate (HP:0002490)1.66049874
94Pulmonary fibrosis (HP:0002206)1.65127190
95Abnormality of renal resorption (HP:0011038)1.64101789
96Disproportionate short-trunk short stature (HP:0003521)1.63259032
97Abnormal mitochondria in muscle tissue (HP:0008316)1.62791330
98Acute encephalopathy (HP:0006846)1.62724189
99Abnormality of femoral epiphyses (HP:0006499)1.62565859
100Abnormality involving the epiphyses of the lower limbs (HP:0006500)1.62565859

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK7.98944928
2MAP4K16.96023917
3BCKDK3.82463831
4TAOK311.8909256
5ZAP701.75974451
6TESK21.75218105
7IKBKE0.97537791
8ADRBK20.86538363
9PRPF4B0.80068657
10ITK0.79766049
11SYK0.78551726
12TLK10.76954043
13CAMK1D0.76054954
14PIK3CA0.72555513
15SGK10.72392636
16LIMK10.69211722
17TBK10.66884671
18PINK10.65070617
19IKBKB0.62321727
20LCK0.61715372
21GRK10.60704059
22NLK0.59411929
23LYN0.58758300
24TESK10.58618989
25ZAK0.58185589
26WNK40.57186995
27MAP4K20.55132362
28HCK0.50036072
29JAK10.49558080
30TYRO30.48112419
31ATR0.43923881
32BMPR1B0.43543888
33IGF1R0.40716009
34INSRR0.40690683
35FRK0.39542576
36MAPK130.37722246
37GRK70.36121852
38CAMK1G0.36036538
39KDR0.33253126
40STK390.32792648
41PDK20.32619852
42DAPK30.32324310
43TIE10.31476211
44PRKCQ0.31412988
45OXSR10.29215036
46PIM10.29017956
47ERBB20.28748697
48TEC0.28500140
49BTK0.28267169
50OBSCN0.27258237
51FYN0.27010120
52MAPK150.26580996
53BLK0.25431262
54CAMK10.24404170
55GRK60.24117097
56CSNK1G10.23557003
57PASK0.23541178
58RPS6KA50.23030012
59ADRBK10.21734742
60MAPK120.21396986
61CSNK1A10.21208901
62SRPK10.20862235
63FES0.18231231
64CAMKK20.18060252
65MUSK0.17329369
66PRKCA0.17298688
67DYRK1A0.17181851
68MAP3K50.16777119
69WNK30.16387596
70SGK20.14976953
71PRKCG0.14907942
72PRKACA0.14875218
73PRKAA20.14335384
74STK160.13803323
75JAK30.13562783
76PHKG10.13557258
77PHKG20.13557258
78CSNK2A10.13159814
79CAMKK10.13063805
80GSK3A0.12593330
81AKT20.12539209
82INSR0.11954127
83MAPK30.11356313
84EPHA40.11220745
85KIT0.11217267
86PRKAA10.10685249
87RPS6KA40.10678201
88AKT10.09475038
89SGK4940.09417010
90SGK2230.09417010
91ERBB30.09358641
92MAP3K120.09345078
93ATM0.09314158
94ACVR1B0.09110359
95CDK190.09101147
96NME20.09000882
97CAMK2A0.08655003
98RPS6KA60.08001972
99MAP3K110.07668639
100CSNK2A20.06654702

Predicted pathways (KEGG)

RankGene SetZ-score
1Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006304.30999446
2Allograft rejection_Homo sapiens_hsa053303.40799440
3Ribosome_Homo sapiens_hsa030103.33075916
4Autoimmune thyroid disease_Homo sapiens_hsa053203.26309320
5Asthma_Homo sapiens_hsa053103.18365760
6Graft-versus-host disease_Homo sapiens_hsa053323.01466228
7Oxidative phosphorylation_Homo sapiens_hsa001902.95527867
8Type I diabetes mellitus_Homo sapiens_hsa049402.62289204
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.57064049
10Parkinsons disease_Homo sapiens_hsa050122.23679311
11Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046502.14970692
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.12400472
13Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.07004444
14Staphylococcus aureus infection_Homo sapiens_hsa051501.94985739
15Pyruvate metabolism_Homo sapiens_hsa006201.93923789
16Linoleic acid metabolism_Homo sapiens_hsa005911.75875835
17Fanconi anemia pathway_Homo sapiens_hsa034601.75856707
18Cardiac muscle contraction_Homo sapiens_hsa042601.69282092
19Antigen processing and presentation_Homo sapiens_hsa046121.64601465
20Primary bile acid biosynthesis_Homo sapiens_hsa001201.59687385
21Primary immunodeficiency_Homo sapiens_hsa053401.59095360
22Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.55804806
23Propanoate metabolism_Homo sapiens_hsa006401.53688372
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.50611175
25Ether lipid metabolism_Homo sapiens_hsa005651.48291686
26Rheumatoid arthritis_Homo sapiens_hsa053231.46274380
27Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.42677271
28Viral myocarditis_Homo sapiens_hsa054161.41911388
29Hematopoietic cell lineage_Homo sapiens_hsa046401.39931356
30Alzheimers disease_Homo sapiens_hsa050101.37356187
312-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.31973333
32Phototransduction_Homo sapiens_hsa047441.29732248
33Caffeine metabolism_Homo sapiens_hsa002321.27372494
34Proteasome_Homo sapiens_hsa030501.26133653
35Protein export_Homo sapiens_hsa030601.21408519
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.20690451
37RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.16778955
38Galactose metabolism_Homo sapiens_hsa000521.10393690
39Huntingtons disease_Homo sapiens_hsa050161.10383274
40Malaria_Homo sapiens_hsa051441.07472189
41Basal transcription factors_Homo sapiens_hsa030221.05625633
42Butanoate metabolism_Homo sapiens_hsa006501.02304986
43Vitamin digestion and absorption_Homo sapiens_hsa049770.99986595
44Leishmaniasis_Homo sapiens_hsa051400.98878319
45SNARE interactions in vesicular transport_Homo sapiens_hsa041300.98343935
46T cell receptor signaling pathway_Homo sapiens_hsa046600.97148928
47Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91148089
48Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.88572396
49Lysosome_Homo sapiens_hsa041420.83146590
50Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.80493399
51Arachidonic acid metabolism_Homo sapiens_hsa005900.79539756
52Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.79342791
53Fat digestion and absorption_Homo sapiens_hsa049750.71907595
54Systemic lupus erythematosus_Homo sapiens_hsa053220.69339671
55Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.68521021
56Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.67028417
57Morphine addiction_Homo sapiens_hsa050320.66583263
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65183072
59Mismatch repair_Homo sapiens_hsa034300.64747792
60Olfactory transduction_Homo sapiens_hsa047400.63412255
61Salivary secretion_Homo sapiens_hsa049700.62381969
62Phagosome_Homo sapiens_hsa041450.61932053
63Ovarian steroidogenesis_Homo sapiens_hsa049130.58302322
64Pancreatic secretion_Homo sapiens_hsa049720.55978878
65Retinol metabolism_Homo sapiens_hsa008300.52921935
66Steroid hormone biosynthesis_Homo sapiens_hsa001400.52869749
67Bile secretion_Homo sapiens_hsa049760.52609418
68Nitrogen metabolism_Homo sapiens_hsa009100.52293663
69Tryptophan metabolism_Homo sapiens_hsa003800.51245393
70Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.50755357
71Chemical carcinogenesis_Homo sapiens_hsa052040.50264973
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.50227938
73Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.49158839
74Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.46481328
75Maturity onset diabetes of the young_Homo sapiens_hsa049500.45209174
76Pertussis_Homo sapiens_hsa051330.41267516
77Mineral absorption_Homo sapiens_hsa049780.40279482
78Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.38929277
79Carbohydrate digestion and absorption_Homo sapiens_hsa049730.38232640
80Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.37031361
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.36039556
82Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.34908492
83Taste transduction_Homo sapiens_hsa047420.34764014
84Herpes simplex infection_Homo sapiens_hsa051680.34281809
85Metabolic pathways_Homo sapiens_hsa011000.33024783
86Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.32424702
87Protein digestion and absorption_Homo sapiens_hsa049740.32145160
88Collecting duct acid secretion_Homo sapiens_hsa049660.31740346
89Serotonergic synapse_Homo sapiens_hsa047260.30454912
90Glutamatergic synapse_Homo sapiens_hsa047240.29083669
91Nicotine addiction_Homo sapiens_hsa050330.28221944
92Tuberculosis_Homo sapiens_hsa051520.26555763
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.25817961
94Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.24671715
95RNA degradation_Homo sapiens_hsa030180.23710397
96Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.21449898
97Osteoclast differentiation_Homo sapiens_hsa043800.21107891
98Peroxisome_Homo sapiens_hsa041460.21072997
99Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.18320711
100Purine metabolism_Homo sapiens_hsa002300.18178096

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »