

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | glyoxylate metabolic process (GO:0046487) | 9.89549090 |
| 2 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 9.85922733 |
| 3 | ectoderm development (GO:0007398) | 8.84499363 |
| 4 | female gonad development (GO:0008585) | 6.72606878 |
| 5 | inner mitochondrial membrane organization (GO:0007007) | 6.65823310 |
| 6 | regulation of telomere maintenance via telomerase (GO:0032210) | 6.51570039 |
| 7 | negative regulation of telomere maintenance (GO:0032205) | 6.48295826 |
| 8 | male meiosis (GO:0007140) | 5.75012747 |
| 9 | thyroid hormone generation (GO:0006590) | 5.66818461 |
| 10 | cranial suture morphogenesis (GO:0060363) | 5.03746341 |
| 11 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 4.95785780 |
| 12 | central nervous system neuron axonogenesis (GO:0021955) | 4.82514819 |
| 13 | regulation of protein glycosylation (GO:0060049) | 4.79035643 |
| 14 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 4.78043028 |
| 15 | response to hepatocyte growth factor (GO:0035728) | 4.78043028 |
| 16 | stress granule assembly (GO:0034063) | 4.75625979 |
| 17 | thyroid hormone metabolic process (GO:0042403) | 4.73524486 |
| 18 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.71553005 |
| 19 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.71553005 |
| 20 | regulation of G0 to G1 transition (GO:0070316) | 4.68416084 |
| 21 | positive regulation of keratinocyte differentiation (GO:0045618) | 4.67350945 |
| 22 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.62326287 |
| 23 | apoptotic DNA fragmentation (GO:0006309) | 4.61440751 |
| 24 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 4.56972012 |
| 25 | viral transcription (GO:0019083) | 4.49611868 |
| 26 | DNA strand renaturation (GO:0000733) | 4.26007835 |
| 27 | viral protein processing (GO:0019082) | 4.23235204 |
| 28 | protein-cofactor linkage (GO:0018065) | 4.22689135 |
| 29 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.21135983 |
| 30 | ATP synthesis coupled proton transport (GO:0015986) | 4.21135983 |
| 31 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.17458905 |
| 32 | mast cell activation (GO:0045576) | 4.16324539 |
| 33 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.14010100 |
| 34 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.14010100 |
| 35 | translational termination (GO:0006415) | 4.09275827 |
| 36 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 4.08334294 |
| 37 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.92903488 |
| 38 | peptidyl-lysine dimethylation (GO:0018027) | 3.91361135 |
| 39 | intermediate filament cytoskeleton organization (GO:0045104) | 3.89751883 |
| 40 | phospholipid translocation (GO:0045332) | 3.82309106 |
| 41 | lipid translocation (GO:0034204) | 3.82309106 |
| 42 | intermediate filament-based process (GO:0045103) | 3.81551029 |
| 43 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.80727843 |
| 44 | ribosomal small subunit assembly (GO:0000028) | 3.77104880 |
| 45 | negative regulation of glycoprotein metabolic process (GO:1903019) | 3.69385738 |
| 46 | natural killer cell activation (GO:0030101) | 3.66833824 |
| 47 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.60724135 |
| 48 | viral life cycle (GO:0019058) | 3.59668726 |
| 49 | cotranslational protein targeting to membrane (GO:0006613) | 3.59293516 |
| 50 | centrosome duplication (GO:0051298) | 3.59123976 |
| 51 | heart trabecula morphogenesis (GO:0061384) | 3.56980894 |
| 52 | intracellular protein transmembrane import (GO:0044743) | 3.56181394 |
| 53 | protein targeting to ER (GO:0045047) | 3.54980376 |
| 54 | maintenance of protein location in nucleus (GO:0051457) | 3.48446127 |
| 55 | mitotic G2 DNA damage checkpoint (GO:0007095) | 3.48207282 |
| 56 | reactive oxygen species biosynthetic process (GO:1903409) | 3.45015863 |
| 57 | ribosomal small subunit biogenesis (GO:0042274) | 3.43219906 |
| 58 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.35831213 |
| 59 | protein localization to endoplasmic reticulum (GO:0070972) | 3.35793245 |
| 60 | negative regulation of protein tyrosine kinase activity (GO:0061099) | 3.33914005 |
| 61 | translational elongation (GO:0006414) | 3.33262042 |
| 62 | cellular protein complex disassembly (GO:0043624) | 3.30126416 |
| 63 | galactose metabolic process (GO:0006012) | 3.26710907 |
| 64 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.25274301 |
| 65 | regulation of telomere maintenance (GO:0032204) | 3.24296734 |
| 66 | parturition (GO:0007567) | 3.23354578 |
| 67 | regulation of sister chromatid cohesion (GO:0007063) | 3.20318317 |
| 68 | RNA destabilization (GO:0050779) | 3.15725661 |
| 69 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 3.15580746 |
| 70 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 3.08002410 |
| 71 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.05955868 |
| 72 | positive regulation of epidermal cell differentiation (GO:0045606) | 3.05477924 |
| 73 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.03583713 |
| 74 | superoxide anion generation (GO:0042554) | 3.00747042 |
| 75 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.99779389 |
| 76 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.97205656 |
| 77 | regulation of histone phosphorylation (GO:0033127) | 2.97134739 |
| 78 | trabecula morphogenesis (GO:0061383) | 2.96138142 |
| 79 | negative regulation of receptor activity (GO:2000272) | 2.95700264 |
| 80 | regulation of rhodopsin mediated signaling pathway (GO:0022400) | 2.94414118 |
| 81 | middle ear morphogenesis (GO:0042474) | 2.92576368 |
| 82 | cellular response to interleukin-15 (GO:0071350) | 2.91790302 |
| 83 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 2.89346800 |
| 84 | behavioral response to nicotine (GO:0035095) | 2.88932064 |
| 85 | vitamin transmembrane transport (GO:0035461) | 2.83367732 |
| 86 | regulation of cell killing (GO:0031341) | 2.82966610 |
| 87 | mitotic G2/M transition checkpoint (GO:0044818) | 2.74593352 |
| 88 | replication fork processing (GO:0031297) | 2.74352185 |
| 89 | signal peptide processing (GO:0006465) | 2.73151845 |
| 90 | androgen biosynthetic process (GO:0006702) | 2.73072148 |
| 91 | craniofacial suture morphogenesis (GO:0097094) | 2.72907748 |
| 92 | maturation of SSU-rRNA (GO:0030490) | 2.71709643 |
| 93 | rhodopsin mediated signaling pathway (GO:0016056) | 2.66398169 |
| 94 | response to thyroid hormone (GO:0097066) | 2.66005575 |
| 95 | cellular ketone body metabolic process (GO:0046950) | 2.65441229 |
| 96 | fatty acid transmembrane transport (GO:1902001) | 2.64665729 |
| 97 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.63754836 |
| 98 | neurofilament cytoskeleton organization (GO:0060052) | 15.0142975 |
| 99 | regulation of DNA methylation (GO:0044030) | 11.4968060 |
| 100 | chaperone-mediated protein transport (GO:0072321) | 10.2365148 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.36266135 |
| 2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.57388218 |
| 3 | IRF1_19129219_ChIP-ChIP_H3396_Human | 4.33345945 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 4.22265262 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.84143076 |
| 6 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.74566587 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.71368056 |
| 8 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.48337228 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.45968715 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.44784919 |
| 11 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.00126187 |
| 12 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.96555474 |
| 13 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.94499523 |
| 14 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.89341933 |
| 15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.80717270 |
| 16 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80708086 |
| 17 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.73202143 |
| 18 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61738397 |
| 19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.48020955 |
| 20 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.47550076 |
| 21 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.44306276 |
| 22 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.40794683 |
| 23 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.40494910 |
| 24 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.39497844 |
| 25 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.38618911 |
| 26 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.37067938 |
| 27 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.36625098 |
| 28 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.36625098 |
| 29 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.36599440 |
| 30 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.35664051 |
| 31 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.32291907 |
| 32 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.31944060 |
| 33 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.31203436 |
| 34 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.30675862 |
| 35 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.29251273 |
| 36 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.28568618 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.28453092 |
| 38 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.28040927 |
| 39 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.27569029 |
| 40 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.26793634 |
| 41 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.19812199 |
| 42 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.19490950 |
| 43 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.19419047 |
| 44 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.18090465 |
| 45 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.15932833 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15029557 |
| 47 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.13005234 |
| 48 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.10620892 |
| 49 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.09673941 |
| 50 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.09378130 |
| 51 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.08687955 |
| 52 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.07546841 |
| 53 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.07378986 |
| 54 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.06744474 |
| 55 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.06011645 |
| 56 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.05866054 |
| 57 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.03851699 |
| 58 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.03411678 |
| 59 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01661668 |
| 60 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.00509967 |
| 61 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 0.99135949 |
| 62 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.98332568 |
| 63 | NCOR_22424771_ChIP-Seq_293T_Human | 0.96012910 |
| 64 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.94347431 |
| 65 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.93742274 |
| 66 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.92306988 |
| 67 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.92165640 |
| 68 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.91676477 |
| 69 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.90897628 |
| 70 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.90246419 |
| 71 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.90020914 |
| 72 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.88962626 |
| 73 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.88336655 |
| 74 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.87865336 |
| 75 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.87441096 |
| 76 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.85341342 |
| 77 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.84574701 |
| 78 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.83954880 |
| 79 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.82669456 |
| 80 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.82351719 |
| 81 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.81672011 |
| 82 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.81473496 |
| 83 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.81222666 |
| 84 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.80263592 |
| 85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.80228966 |
| 86 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.78982067 |
| 87 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.78865534 |
| 88 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.78116799 |
| 89 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.77530016 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.76973573 |
| 91 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.76719738 |
| 92 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.76428134 |
| 93 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.76253558 |
| 94 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.75663823 |
| 95 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.75434259 |
| 96 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.75412816 |
| 97 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.75395667 |
| 98 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.75099198 |
| 99 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.74622033 |
| 100 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.74577209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008995_early_reproductive_senescence | 9.21231488 |
| 2 | MP0002876_abnormal_thyroid_physiology | 4.18027775 |
| 3 | MP0005671_abnormal_response_to | 3.74864471 |
| 4 | MP0003786_premature_aging | 3.70265735 |
| 5 | MP0002653_abnormal_ependyma_morphology | 3.65923152 |
| 6 | MP0006082_CNS_inflammation | 2.95101940 |
| 7 | MP0001986_abnormal_taste_sensitivity | 2.66241040 |
| 8 | MP0004885_abnormal_endolymph | 2.54756969 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.54339906 |
| 10 | MP0003763_abnormal_thymus_physiology | 2.48860731 |
| 11 | MP0009379_abnormal_foot_pigmentation | 2.24001774 |
| 12 | MP0004264_abnormal_extraembryonic_tissu | 2.07844926 |
| 13 | MP0009785_altered_susceptibility_to | 1.83450098 |
| 14 | MP0004742_abnormal_vestibular_system | 1.83176039 |
| 15 | MP0006276_abnormal_autonomic_nervous | 1.73804306 |
| 16 | MP0005387_immune_system_phenotype | 1.73278308 |
| 17 | MP0001790_abnormal_immune_system | 1.73278308 |
| 18 | MP0005360_urolithiasis | 1.66863649 |
| 19 | MP0004019_abnormal_vitamin_homeostasis | 1.64897920 |
| 20 | MP0005025_abnormal_response_to | 1.60982000 |
| 21 | MP0002132_abnormal_respiratory_system | 1.58653267 |
| 22 | MP0009333_abnormal_splenocyte_physiolog | 1.50674911 |
| 23 | MP0002723_abnormal_immune_serum | 1.48060812 |
| 24 | MP0002420_abnormal_adaptive_immunity | 1.44858081 |
| 25 | MP0003646_muscle_fatigue | 1.44732613 |
| 26 | MP0001800_abnormal_humoral_immune | 1.42923095 |
| 27 | MP0010386_abnormal_urinary_bladder | 1.42642129 |
| 28 | MP0005085_abnormal_gallbladder_physiolo | 1.40731079 |
| 29 | MP0001849_ear_inflammation | 1.40360952 |
| 30 | MP0005000_abnormal_immune_tolerance | 1.39915985 |
| 31 | MP0001819_abnormal_immune_cell | 1.39861469 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.33541446 |
| 33 | MP0003878_abnormal_ear_physiology | 1.33541446 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.29122047 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.28544388 |
| 36 | MP0003866_abnormal_defecation | 1.28252222 |
| 37 | MP0001835_abnormal_antigen_presentation | 1.21618847 |
| 38 | MP0010094_abnormal_chromosome_stability | 1.17866793 |
| 39 | MP0002127_abnormal_cardiovascular_syste | 1.17112321 |
| 40 | MP0003879_abnormal_hair_cell | 1.16689517 |
| 41 | MP0001119_abnormal_female_reproductive | 1.14274346 |
| 42 | MP0001440_abnormal_grooming_behavior | 1.11895018 |
| 43 | MP0006292_abnormal_olfactory_placode | 1.10229546 |
| 44 | MP0001666_abnormal_nutrient_absorption | 1.09467490 |
| 45 | MP0000716_abnormal_immune_system | 1.09156612 |
| 46 | MP0002398_abnormal_bone_marrow | 1.07910035 |
| 47 | MP0005551_abnormal_eye_electrophysiolog | 1.04107580 |
| 48 | MP0005084_abnormal_gallbladder_morpholo | 1.03172345 |
| 49 | MP0002452_abnormal_antigen_presenting | 1.03061342 |
| 50 | MP0003436_decreased_susceptibility_to | 1.02051684 |
| 51 | MP0003011_delayed_dark_adaptation | 1.00048302 |
| 52 | MP0003936_abnormal_reproductive_system | 0.96283716 |
| 53 | MP0000569_abnormal_digit_pigmentation | 0.91727009 |
| 54 | MP0001881_abnormal_mammary_gland | 0.90431929 |
| 55 | MP0002429_abnormal_blood_cell | 0.89295954 |
| 56 | MP0005645_abnormal_hypothalamus_physiol | 0.88293673 |
| 57 | MP0000343_altered_response_to | 0.88073601 |
| 58 | MP0004142_abnormal_muscle_tone | 0.88063723 |
| 59 | MP0002837_dystrophic_cardiac_calcinosis | 0.88029426 |
| 60 | MP0002638_abnormal_pupillary_reflex | 0.86716875 |
| 61 | MP0009046_muscle_twitch | 0.86382729 |
| 62 | MP0002163_abnormal_gland_morphology | 0.85556964 |
| 63 | MP0001542_abnormal_bone_strength | 0.81167768 |
| 64 | MP0008877_abnormal_DNA_methylation | 0.81136947 |
| 65 | MP0009764_decreased_sensitivity_to | 0.79514732 |
| 66 | MP0002138_abnormal_hepatobiliary_system | 0.79265473 |
| 67 | MP0005464_abnormal_platelet_physiology | 0.78132889 |
| 68 | MP0000604_amyloidosis | 0.75804033 |
| 69 | MP0008775_abnormal_heart_ventricle | 0.74988470 |
| 70 | MP0001919_abnormal_reproductive_system | 0.74935353 |
| 71 | MP0006072_abnormal_retinal_apoptosis | 0.74318805 |
| 72 | MP0003195_calcinosis | 0.74264549 |
| 73 | MP0003699_abnormal_female_reproductive | 0.73827288 |
| 74 | MP0008872_abnormal_physiological_respon | 0.73506150 |
| 75 | MP0001984_abnormal_olfaction | 0.73356330 |
| 76 | MP0002210_abnormal_sex_determination | 0.73113707 |
| 77 | MP0005646_abnormal_pituitary_gland | 0.72894184 |
| 78 | MP0002277_abnormal_respiratory_mucosa | 0.72389654 |
| 79 | MP0001845_abnormal_inflammatory_respons | 0.71865976 |
| 80 | MP0010155_abnormal_intestine_physiology | 0.71398896 |
| 81 | MP0002697_abnormal_eye_size | 0.70436131 |
| 82 | MP0002095_abnormal_skin_pigmentation | 0.69704653 |
| 83 | MP0000685_abnormal_immune_system | 0.68503566 |
| 84 | MP0003186_abnormal_redox_activity | 0.67523652 |
| 85 | MP0001905_abnormal_dopamine_level | 0.64816070 |
| 86 | MP0003632_abnormal_nervous_system | 0.64388368 |
| 87 | MP0005379_endocrine/exocrine_gland_phen | 0.63529359 |
| 88 | MP0005174_abnormal_tail_pigmentation | 0.63005267 |
| 89 | MP0010329_abnormal_lipoprotein_level | 0.62286735 |
| 90 | MP0002419_abnormal_innate_immunity | 0.61768060 |
| 91 | MP0002229_neurodegeneration | 0.61729209 |
| 92 | MP0002102_abnormal_ear_morphology | 0.61664803 |
| 93 | MP0002734_abnormal_mechanical_nocicepti | 0.60921360 |
| 94 | MP0003111_abnormal_nucleus_morphology | 0.60819479 |
| 95 | MP0005332_abnormal_amino_acid | 0.60501518 |
| 96 | MP0005389_reproductive_system_phenotype | 0.59360977 |
| 97 | MP0002405_respiratory_system_inflammati | 0.58358383 |
| 98 | MP0004947_skin_inflammation | 0.57388246 |
| 99 | MP0004270_analgesia | 0.57276013 |
| 100 | MP0001968_abnormal_touch/_nociception | 0.57233621 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 9.43506967 |
| 2 | Duplicated collecting system (HP:0000081) | 8.82188202 |
| 3 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 8.32139305 |
| 4 | Abnormality of the renal collecting system (HP:0004742) | 8.02731243 |
| 5 | Chromsome breakage (HP:0040012) | 7.29248175 |
| 6 | Abnormality of pyrimidine metabolism (HP:0004353) | 7.18559077 |
| 7 | Abnormality of DNA repair (HP:0003254) | 6.57875393 |
| 8 | Oral leukoplakia (HP:0002745) | 5.95115239 |
| 9 | Aplastic anemia (HP:0001915) | 5.89988933 |
| 10 | Autoimmune thrombocytopenia (HP:0001973) | 5.20932627 |
| 11 | Ureteral duplication (HP:0000073) | 5.19375440 |
| 12 | Duplication of thumb phalanx (HP:0009942) | 5.05938368 |
| 13 | Absent thumb (HP:0009777) | 4.46043027 |
| 14 | Ectopic kidney (HP:0000086) | 4.41556114 |
| 15 | Increased serum pyruvate (HP:0003542) | 4.39279105 |
| 16 | Abnormality of T cell number (HP:0011839) | 3.78566933 |
| 17 | Pancytopenia (HP:0001876) | 3.64916971 |
| 18 | Abnormality of B cell number (HP:0010975) | 3.61935629 |
| 19 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.60542189 |
| 20 | Renal cortical cysts (HP:0000803) | 3.60354370 |
| 21 | Enlarged epiphyses (HP:0010580) | 3.55614113 |
| 22 | Abnormality of glycolysis (HP:0004366) | 3.50625612 |
| 23 | Autoimmune hemolytic anemia (HP:0001890) | 3.45944523 |
| 24 | Eosinophilia (HP:0001880) | 3.44610177 |
| 25 | Increased IgM level (HP:0003496) | 3.36775630 |
| 26 | Thyroid-stimulating hormone excess (HP:0002925) | 3.35097904 |
| 27 | Meckel diverticulum (HP:0002245) | 3.27670163 |
| 28 | Increased hepatocellular lipid droplets (HP:0006565) | 3.22239058 |
| 29 | Stomach cancer (HP:0012126) | 3.19907960 |
| 30 | Abnormality of the ileum (HP:0001549) | 3.19704059 |
| 31 | Abnormality of the preputium (HP:0100587) | 3.15906007 |
| 32 | Abnormality of T cells (HP:0002843) | 2.95031680 |
| 33 | Hypergonadotropic hypogonadism (HP:0000815) | 2.94486677 |
| 34 | Horseshoe kidney (HP:0000085) | 2.92970029 |
| 35 | Absent radius (HP:0003974) | 2.92068487 |
| 36 | Lipid accumulation in hepatocytes (HP:0006561) | 2.85509763 |
| 37 | Aplasia involving forearm bones (HP:0009822) | 2.81245674 |
| 38 | Absent forearm bone (HP:0003953) | 2.81245674 |
| 39 | Abnormality of eosinophils (HP:0001879) | 2.76701566 |
| 40 | Abnormality of reticulocytes (HP:0004312) | 2.74191271 |
| 41 | Clubbing of toes (HP:0100760) | 2.70836896 |
| 42 | Renal Fanconi syndrome (HP:0001994) | 2.66565873 |
| 43 | Granulocytopenia (HP:0001913) | 2.64571763 |
| 44 | Rough bone trabeculation (HP:0100670) | 2.59578757 |
| 45 | Neutropenia (HP:0001875) | 2.58548522 |
| 46 | Joint swelling (HP:0001386) | 2.55410466 |
| 47 | Abnormality of nucleobase metabolism (HP:0010932) | 2.54171103 |
| 48 | Abnormality of chromosome stability (HP:0003220) | 2.53973653 |
| 49 | T lymphocytopenia (HP:0005403) | 2.52344088 |
| 50 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.49681633 |
| 51 | Pallor (HP:0000980) | 2.49285128 |
| 52 | Abnormality of the carotid arteries (HP:0005344) | 2.42091632 |
| 53 | Increased intramyocellular lipid droplets (HP:0012240) | 2.31874493 |
| 54 | Cellular immunodeficiency (HP:0005374) | 2.31825761 |
| 55 | Exertional dyspnea (HP:0002875) | 2.15244861 |
| 56 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.14300231 |
| 57 | Leukopenia (HP:0001882) | 2.13367760 |
| 58 | Abnormality of the renal cortex (HP:0011035) | 2.13247375 |
| 59 | Flattened epiphyses (HP:0003071) | 2.10870817 |
| 60 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.10005800 |
| 61 | Abnormality of the vertebral endplates (HP:0005106) | 2.07454930 |
| 62 | Prostate neoplasm (HP:0100787) | 2.06230980 |
| 63 | Partial duplication of the phalanx of hand (HP:0009999) | 2.06029092 |
| 64 | Bone marrow hypocellularity (HP:0005528) | 2.05615082 |
| 65 | Short thumb (HP:0009778) | 2.01962469 |
| 66 | Nausea (HP:0002018) | 2.00493074 |
| 67 | Duodenal stenosis (HP:0100867) | 1.96235502 |
| 68 | Small intestinal stenosis (HP:0012848) | 1.96235502 |
| 69 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.94856518 |
| 70 | Acute necrotizing encephalopathy (HP:0006965) | 1.94033635 |
| 71 | Abnormal trabecular bone morphology (HP:0100671) | 1.93227449 |
| 72 | Mutism (HP:0002300) | 1.90307669 |
| 73 | Increased muscle lipid content (HP:0009058) | 1.89421878 |
| 74 | Abnormality of urine glucose concentration (HP:0011016) | 1.87761591 |
| 75 | Glycosuria (HP:0003076) | 1.87761591 |
| 76 | Hypochromic anemia (HP:0001931) | 1.86729442 |
| 77 | Mitochondrial inheritance (HP:0001427) | 1.83882892 |
| 78 | Leukocytosis (HP:0001974) | 1.83747013 |
| 79 | Triphalangeal thumb (HP:0001199) | 1.83398119 |
| 80 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 1.81416067 |
| 81 | Spinal cord lesions (HP:0100561) | 1.76224781 |
| 82 | Syringomyelia (HP:0003396) | 1.76224781 |
| 83 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.76124023 |
| 84 | Absent epiphyses (HP:0010577) | 1.76124023 |
| 85 | Tracheoesophageal fistula (HP:0002575) | 1.75182553 |
| 86 | Progressive neurologic deterioration (HP:0002344) | 1.74063539 |
| 87 | Renal agenesis (HP:0000104) | 1.69618340 |
| 88 | Abnormality of the femoral head (HP:0003368) | 1.68481154 |
| 89 | Abnormality of T cell physiology (HP:0011840) | 1.68071644 |
| 90 | Megalocornea (HP:0000485) | 1.67680749 |
| 91 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.67433230 |
| 92 | Cerebral edema (HP:0002181) | 1.66099068 |
| 93 | Increased CSF lactate (HP:0002490) | 1.66049874 |
| 94 | Pulmonary fibrosis (HP:0002206) | 1.65127190 |
| 95 | Abnormality of renal resorption (HP:0011038) | 1.64101789 |
| 96 | Disproportionate short-trunk short stature (HP:0003521) | 1.63259032 |
| 97 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.62791330 |
| 98 | Acute encephalopathy (HP:0006846) | 1.62724189 |
| 99 | Abnormality of femoral epiphyses (HP:0006499) | 1.62565859 |
| 100 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.62565859 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 7.98944928 |
| 2 | MAP4K1 | 6.96023917 |
| 3 | BCKDK | 3.82463831 |
| 4 | TAOK3 | 11.8909256 |
| 5 | ZAP70 | 1.75974451 |
| 6 | TESK2 | 1.75218105 |
| 7 | IKBKE | 0.97537791 |
| 8 | ADRBK2 | 0.86538363 |
| 9 | PRPF4B | 0.80068657 |
| 10 | ITK | 0.79766049 |
| 11 | SYK | 0.78551726 |
| 12 | TLK1 | 0.76954043 |
| 13 | CAMK1D | 0.76054954 |
| 14 | PIK3CA | 0.72555513 |
| 15 | SGK1 | 0.72392636 |
| 16 | LIMK1 | 0.69211722 |
| 17 | TBK1 | 0.66884671 |
| 18 | PINK1 | 0.65070617 |
| 19 | IKBKB | 0.62321727 |
| 20 | LCK | 0.61715372 |
| 21 | GRK1 | 0.60704059 |
| 22 | NLK | 0.59411929 |
| 23 | LYN | 0.58758300 |
| 24 | TESK1 | 0.58618989 |
| 25 | ZAK | 0.58185589 |
| 26 | WNK4 | 0.57186995 |
| 27 | MAP4K2 | 0.55132362 |
| 28 | HCK | 0.50036072 |
| 29 | JAK1 | 0.49558080 |
| 30 | TYRO3 | 0.48112419 |
| 31 | ATR | 0.43923881 |
| 32 | BMPR1B | 0.43543888 |
| 33 | IGF1R | 0.40716009 |
| 34 | INSRR | 0.40690683 |
| 35 | FRK | 0.39542576 |
| 36 | MAPK13 | 0.37722246 |
| 37 | GRK7 | 0.36121852 |
| 38 | CAMK1G | 0.36036538 |
| 39 | KDR | 0.33253126 |
| 40 | STK39 | 0.32792648 |
| 41 | PDK2 | 0.32619852 |
| 42 | DAPK3 | 0.32324310 |
| 43 | TIE1 | 0.31476211 |
| 44 | PRKCQ | 0.31412988 |
| 45 | OXSR1 | 0.29215036 |
| 46 | PIM1 | 0.29017956 |
| 47 | ERBB2 | 0.28748697 |
| 48 | TEC | 0.28500140 |
| 49 | BTK | 0.28267169 |
| 50 | OBSCN | 0.27258237 |
| 51 | FYN | 0.27010120 |
| 52 | MAPK15 | 0.26580996 |
| 53 | BLK | 0.25431262 |
| 54 | CAMK1 | 0.24404170 |
| 55 | GRK6 | 0.24117097 |
| 56 | CSNK1G1 | 0.23557003 |
| 57 | PASK | 0.23541178 |
| 58 | RPS6KA5 | 0.23030012 |
| 59 | ADRBK1 | 0.21734742 |
| 60 | MAPK12 | 0.21396986 |
| 61 | CSNK1A1 | 0.21208901 |
| 62 | SRPK1 | 0.20862235 |
| 63 | FES | 0.18231231 |
| 64 | CAMKK2 | 0.18060252 |
| 65 | MUSK | 0.17329369 |
| 66 | PRKCA | 0.17298688 |
| 67 | DYRK1A | 0.17181851 |
| 68 | MAP3K5 | 0.16777119 |
| 69 | WNK3 | 0.16387596 |
| 70 | SGK2 | 0.14976953 |
| 71 | PRKCG | 0.14907942 |
| 72 | PRKACA | 0.14875218 |
| 73 | PRKAA2 | 0.14335384 |
| 74 | STK16 | 0.13803323 |
| 75 | JAK3 | 0.13562783 |
| 76 | PHKG1 | 0.13557258 |
| 77 | PHKG2 | 0.13557258 |
| 78 | CSNK2A1 | 0.13159814 |
| 79 | CAMKK1 | 0.13063805 |
| 80 | GSK3A | 0.12593330 |
| 81 | AKT2 | 0.12539209 |
| 82 | INSR | 0.11954127 |
| 83 | MAPK3 | 0.11356313 |
| 84 | EPHA4 | 0.11220745 |
| 85 | KIT | 0.11217267 |
| 86 | PRKAA1 | 0.10685249 |
| 87 | RPS6KA4 | 0.10678201 |
| 88 | AKT1 | 0.09475038 |
| 89 | SGK494 | 0.09417010 |
| 90 | SGK223 | 0.09417010 |
| 91 | ERBB3 | 0.09358641 |
| 92 | MAP3K12 | 0.09345078 |
| 93 | ATM | 0.09314158 |
| 94 | ACVR1B | 0.09110359 |
| 95 | CDK19 | 0.09101147 |
| 96 | NME2 | 0.09000882 |
| 97 | CAMK2A | 0.08655003 |
| 98 | RPS6KA6 | 0.08001972 |
| 99 | MAP3K11 | 0.07668639 |
| 100 | CSNK2A2 | 0.06654702 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 4.30999446 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.40799440 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.33075916 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.26309320 |
| 5 | Asthma_Homo sapiens_hsa05310 | 3.18365760 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.01466228 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.95527867 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.62289204 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.57064049 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.23679311 |
| 11 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.14970692 |
| 12 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.12400472 |
| 13 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.07004444 |
| 14 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.94985739 |
| 15 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.93923789 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.75875835 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.75856707 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.69282092 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.64601465 |
| 20 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.59687385 |
| 21 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.59095360 |
| 22 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.55804806 |
| 23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.53688372 |
| 24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.50611175 |
| 25 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.48291686 |
| 26 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.46274380 |
| 27 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.42677271 |
| 28 | Viral myocarditis_Homo sapiens_hsa05416 | 1.41911388 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.39931356 |
| 30 | Alzheimers disease_Homo sapiens_hsa05010 | 1.37356187 |
| 31 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.31973333 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.29732248 |
| 33 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.27372494 |
| 34 | Proteasome_Homo sapiens_hsa03050 | 1.26133653 |
| 35 | Protein export_Homo sapiens_hsa03060 | 1.21408519 |
| 36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.20690451 |
| 37 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.16778955 |
| 38 | Galactose metabolism_Homo sapiens_hsa00052 | 1.10393690 |
| 39 | Huntingtons disease_Homo sapiens_hsa05016 | 1.10383274 |
| 40 | Malaria_Homo sapiens_hsa05144 | 1.07472189 |
| 41 | Basal transcription factors_Homo sapiens_hsa03022 | 1.05625633 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02304986 |
| 43 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.99986595 |
| 44 | Leishmaniasis_Homo sapiens_hsa05140 | 0.98878319 |
| 45 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.98343935 |
| 46 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.97148928 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.91148089 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.88572396 |
| 49 | Lysosome_Homo sapiens_hsa04142 | 0.83146590 |
| 50 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.80493399 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79539756 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.79342791 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.71907595 |
| 54 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.69339671 |
| 55 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.68521021 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.67028417 |
| 57 | Morphine addiction_Homo sapiens_hsa05032 | 0.66583263 |
| 58 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.65183072 |
| 59 | Mismatch repair_Homo sapiens_hsa03430 | 0.64747792 |
| 60 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63412255 |
| 61 | Salivary secretion_Homo sapiens_hsa04970 | 0.62381969 |
| 62 | Phagosome_Homo sapiens_hsa04145 | 0.61932053 |
| 63 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.58302322 |
| 64 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.55978878 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.52921935 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52869749 |
| 67 | Bile secretion_Homo sapiens_hsa04976 | 0.52609418 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.52293663 |
| 69 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.51245393 |
| 70 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.50755357 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50264973 |
| 72 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.50227938 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49158839 |
| 74 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.46481328 |
| 75 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.45209174 |
| 76 | Pertussis_Homo sapiens_hsa05133 | 0.41267516 |
| 77 | Mineral absorption_Homo sapiens_hsa04978 | 0.40279482 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.38929277 |
| 79 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.38232640 |
| 80 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.37031361 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.36039556 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34908492 |
| 83 | Taste transduction_Homo sapiens_hsa04742 | 0.34764014 |
| 84 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.34281809 |
| 85 | Metabolic pathways_Homo sapiens_hsa01100 | 0.33024783 |
| 86 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.32424702 |
| 87 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.32145160 |
| 88 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.31740346 |
| 89 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.30454912 |
| 90 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.29083669 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.28221944 |
| 92 | Tuberculosis_Homo sapiens_hsa05152 | 0.26555763 |
| 93 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.25817961 |
| 94 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.24671715 |
| 95 | RNA degradation_Homo sapiens_hsa03018 | 0.23710397 |
| 96 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.21449898 |
| 97 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.21107891 |
| 98 | Peroxisome_Homo sapiens_hsa04146 | 0.21072997 |
| 99 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.18320711 |
| 100 | Purine metabolism_Homo sapiens_hsa00230 | 0.18178096 |

