ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	* viral life cycle (GO:0019058)	9.98681388
2	* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)	9.70182510
3	maturation of SSU-rRNA (GO:0030490)	9.28986836
4	* translational initiation (GO:0006413)	8.71030239
5	* protein complex disassembly (GO:0043241)	8.56395971
6	* macromolecular complex disassembly (GO:0032984)	7.95650139
7	* protein targeting to membrane (GO:0006612)	7.28886554
8	ribosomal large subunit biogenesis (GO:0042273)	7.28138760
9	* nuclear-transcribed mRNA catabolic process (GO:0000956)	6.49129003
10	* mRNA catabolic process (GO:0006402)	6.15150469
11	mitochondrial ATP synthesis coupled proton transport (GO:0042776)	5.92279080
12	* translation (GO:0006412)	5.91466555
13	ATP synthesis coupled proton transport (GO:0015986)	5.70161367
14	energy coupled proton transport, down electrochemical gradient (GO:0015985)	5.70161367
15	* RNA catabolic process (GO:0006401)	5.49926775
16	ribonucleoprotein complex biogenesis (GO:0022613)	5.03477405
17	* establishment of protein localization to membrane (GO:0090150)	4.89721585
18	* protein targeting (GO:0006605)	4.38696837
19	mitochondrial electron transport, NADH to ubiquinone (GO:0006120)	4.17904097
20	sequestering of actin monomers (GO:0042989)	4.12157470
21	protein complex biogenesis (GO:0070271)	4.10987010
22	* establishment of protein localization to organelle (GO:0072594)	4.08684142
23	* protein localization to membrane (GO:0072657)	3.86348902
24	mitochondrial respiratory chain complex assembly (GO:0033108)	3.85747186
25	cellular component biogenesis (GO:0044085)	3.83375612
26	respiratory electron transport chain (GO:0022904)	3.79140173
27	rRNA processing (GO:0006364)	3.79109911
28	pyrimidine deoxyribonucleotide catabolic process (GO:0009223)	3.76000236
29	electron transport chain (GO:0022900)	3.70228878
30	rRNA metabolic process (GO:0016072)	3.62970646
31	behavioral response to nicotine (GO:0035095)	3.43366685
32	DNA deamination (GO:0045006)	3.42257199
33	ncRNA 3-end processing (GO:0043628)	3.34751826
34	GTP biosynthetic process (GO:0006183)	3.32928657
35	establishment of integrated proviral latency (GO:0075713)	3.27050394
36	pyrimidine nucleotide catabolic process (GO:0006244)	3.22051342
37	protein neddylation (GO:0045116)	3.20703956
38	inner mitochondrial membrane organization (GO:0007007)	3.18401719
39	* cellular component disassembly (GO:0022411)	3.09246596
40	UTP biosynthetic process (GO:0006228)	3.04588501
41	proton transport (GO:0015992)	3.02577769
42	hydrogen transport (GO:0006818)	2.95345734
43	intracellular protein transmembrane import (GO:0044743)	2.91610562
44	neuron fate determination (GO:0048664)	2.90263306
45	establishment of viral latency (GO:0019043)	2.89515988
46	spliceosomal complex assembly (GO:0000245)	2.88788776
47	* protein localization to organelle (GO:0033365)	2.87977779
48	monocyte chemotaxis (GO:0002548)	2.80728818
49	viral protein processing (GO:0019082)	2.80172610
50	establishment of protein localization to mitochondrial membrane (GO:0090151)	2.72305682
51	eosinophil chemotaxis (GO:0048245)	2.71900074
52	purine ribonucleoside triphosphate biosynthetic process (GO:0009206)	2.71548194
53	nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)	2.68720534
54	regulation of mitochondrial translation (GO:0070129)	2.68572757
55	nucleoside triphosphate biosynthetic process (GO:0009142)	2.68347375
56	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	2.66475942
57	tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)	2.66407819
58	RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)	2.66407819
59	termination of RNA polymerase III transcription (GO:0006386)	2.65038996
60	transcription elongation from RNA polymerase III promoter (GO:0006385)	2.65038996
61	establishment of protein localization to mitochondrion (GO:0072655)	2.64563307
62	purine nucleoside triphosphate biosynthetic process (GO:0009145)	2.60358611
63	protein targeting to mitochondrion (GO:0006626)	2.59516005
64	regulation of antigen processing and presentation of peptide antigen (GO:0002583)	2.57083195
65	pyrimidine deoxyribonucleotide metabolic process (GO:0009219)	2.55214726
66	ATP biosynthetic process (GO:0006754)	2.54010919
67	oxidative phosphorylation (GO:0006119)	2.53362487
68	formation of translation preinitiation complex (GO:0001731)	2.53001277
69	UTP metabolic process (GO:0046051)	2.51654400
70	deoxyribonucleoside monophosphate metabolic process (GO:0009162)	2.50590301
71	negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)	2.50054372
72	positive regulation of respiratory burst (GO:0060267)	2.49158544
73	spliceosomal snRNP assembly (GO:0000387)	2.47773014
74	keratinocyte development (GO:0003334)	2.47547724
75	aerobic respiration (GO:0009060)	2.47541013
76	eosinophil migration (GO:0072677)	2.45993472
77	mitochondrial transport (GO:0006839)	2.45503925
78	ribonucleoside triphosphate biosynthetic process (GO:0009201)	2.45364416
79	protein-cofactor linkage (GO:0018065)	2.43536880
80	protein localization to mitochondrion (GO:0070585)	2.43357808
81	purine nucleoside monophosphate biosynthetic process (GO:0009127)	2.41840058
82	purine ribonucleoside monophosphate biosynthetic process (GO:0009168)	2.41840058
83	chromatin remodeling at centromere (GO:0031055)	2.40754650
84	CTP biosynthetic process (GO:0006241)	2.39760835
85	CTP metabolic process (GO:0046036)	2.39760835
86	transcription elongation from RNA polymerase I promoter (GO:0006362)	2.36943731
87	base-excision repair, AP site formation (GO:0006285)	2.32005988
88	* gene expression (GO:0010467)	2.31807536
89	peptidyl-histidine modification (GO:0018202)	2.29282669
90	tongue development (GO:0043586)	2.29160072
91	deoxyribonucleotide catabolic process (GO:0009264)	2.28282962
92	termination of RNA polymerase I transcription (GO:0006363)	2.27737690
93	pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)	2.25189242
94	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:	2.24613518
95	cytochrome complex assembly (GO:0017004)	2.23846512
96	intracellular protein transmembrane transport (GO:0065002)	2.23131408
97	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)	2.22518364
98	histone mRNA metabolic process (GO:0008334)	2.22336815
99	protein transmembrane transport (GO:0071806)	2.21523568
100	cell proliferation in forebrain (GO:0021846)	2.20569034
101	rRNA modification (GO:0000154)	2.18012629
102	pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)	2.16737981
103	guanosine-containing compound biosynthetic process (GO:1901070)	2.16418027
104	negative regulation of RNA splicing (GO:0033119)	2.16222703
105	proteasome assembly (GO:0043248)	2.15392845
106	DNA damage response, detection of DNA damage (GO:0042769)	2.13374435
107	ncRNA processing (GO:0034470)	2.12203653
108	antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)	2.11932104
109	negative regulation of ubiquitin-protein transferase activity (GO:0051444)	2.10657489
110	negative regulation of ligase activity (GO:0051352)	2.10657489
111	hair cycle (GO:0042633)	2.10345548
112	molting cycle (GO:0042303)	2.10345548
113	hydrogen ion transmembrane transport (GO:1902600)	2.10218195
114	chaperone-mediated protein transport (GO:0072321)	2.09779912
115	autophagic vacuole fusion (GO:0000046)	2.09614168
116	* single-organism cellular localization (GO:1902580)	2.09561650
117	platelet dense granule organization (GO:0060155)	2.08193204
118	keratinocyte proliferation (GO:0043616)	2.07437508
119	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00	2.07019821
120	mitochondrial respiratory chain complex I biogenesis (GO:0097031)	2.06094624
121	mitochondrial respiratory chain complex I assembly (GO:0032981)	2.06094624
122	NADH dehydrogenase complex assembly (GO:0010257)	2.06094624
123	7-methylguanosine RNA capping (GO:0009452)	2.01760847
124	RNA capping (GO:0036260)	2.01760847
125	* viral transcription (GO:0019083)	13.6499208
126	ribosomal small subunit biogenesis (GO:0042274)	13.0948943
127	* translational termination (GO:0006415)	12.9685314
128	ribosomal small subunit assembly (GO:0000028)	11.4447513
129	* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)	10.9338381
130	* cotranslational protein targeting to membrane (GO:0006613)	10.8467483
131	* protein targeting to ER (GO:0045047)	10.7921207
132	* translational elongation (GO:0006414)	10.5634971
133	* establishment of protein localization to endoplasmic reticulum (GO:0072599)	10.3463037
134	* protein localization to endoplasmic reticulum (GO:0070972)	10.0736080
135	* cellular protein complex disassembly (GO:0043624)	10.0365480

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	SOX9_22984422_ChIP-ChIP_TESTIS_Rat	9.36027410
2	* MYC_18555785_ChIP-Seq_MESCs_Mouse	4.81058910
3	TP63_17297297_ChIP-ChIP_HaCaT_Human	4.66792199
4	CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human	4.12813903
5	* MYC_19079543_ChIP-ChIP_MESCs_Mouse	4.03691492
6	* EST1_17652178_ChIP-ChIP_JURKAT_Human	3.85042526
7	GABP_17652178_ChIP-ChIP_JURKAT_Human	3.80067203
8	TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat	3.56701304
9	EZH2_22144423_ChIP-Seq_EOC_Human	3.37799978
10	ETS1_20019798_ChIP-Seq_JURKAT_Human	3.23938267
11	KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human	3.19343827
12	HCFC1_20581084_ChIP-Seq_MESCs_Mouse	3.17628734
13	CHD1_19587682_ChIP-ChIP_MESCs_Mouse	3.17357765
14	EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse	3.17215212
15	* XRN2_22483619_ChIP-Seq_HELA_Human	2.89628062
16	TTF2_22483619_ChIP-Seq_HELA_Human	2.77098990
17	* CREB1_15753290_ChIP-ChIP_HEK293T_Human	2.71909538
18	* MYC_18358816_ChIP-ChIP_MESCs_Mouse	2.53826502
19	* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human	2.51628712
20	ELK1_19687146_ChIP-ChIP_HELA_Human	2.51325075
21	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	2.28248966
22	* MYC_19030024_ChIP-ChIP_MESCs_Mouse	2.26258360
23	TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse	2.24616902
24	STAT6_21828071_ChIP-Seq_BEAS2B_Human	2.20815488
25	ELK1_22589737_ChIP-Seq_MCF10A_Human	2.16228077
26	JARID1A_20064375_ChIP-Seq_MESCs_Mouse	2.13309363
27	* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse	2.08958445
28	KLF4_19030024_ChIP-ChIP_MESCs_Mouse	2.03531784
29	VDR_23849224_ChIP-Seq_CD4+_Human	2.02330181
30	ELF1_17652178_ChIP-ChIP_JURKAT_Human	1.94615639
31	E2F7_22180533_ChIP-Seq_HELA_Human	1.86336319
32	FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human	1.83262569
33	BP1_19119308_ChIP-ChIP_Hs578T_Human	1.83150682
34	DCP1A_22483619_ChIP-Seq_HELA_Human	1.80553540
35	MYC_18940864_ChIP-ChIP_HL60_Human	1.78657504
36	E2F4_17652178_ChIP-ChIP_JURKAT_Human	1.73035295
37	TAL1_20887958_ChIP-Seq_HPC-7_Mouse	1.69630885
38	FOXP3_21729870_ChIP-Seq_TREG_Human	1.68333889
39	SRY_22984422_ChIP-ChIP_TESTIS_Rat	1.67632530
40	E2F1_18555785_ChIP-Seq_MESCs_Mouse	1.63895227
41	HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse	1.62422628
42	ZFP42_18358816_ChIP-ChIP_MESCs_Mouse	1.60369828
43	MYBL2_22936984_ChIP-ChIP_MESCs_Mouse	1.58680943
44	IRF1_19129219_ChIP-ChIP_H3396_Human	1.57962326
45	SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse	1.53779929
46	FOXM1_23109430_ChIP-Seq_U2OS_Human	1.45122484
47	POU5F1_18358816_ChIP-ChIP_MESCs_Mouse	1.44960015
48	FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse	1.43975836
49	NOTCH1_17114293_ChIP-ChIP_T-ALL_Human	1.40746454
50	KLF2_18264089_ChIP-ChIP_MESCs_Mouse	1.37587610
51	KLF5_18264089_ChIP-ChIP_MESCs_Mouse	1.37587610
52	KLF4_18264089_ChIP-ChIP_MESCs_Mouse	1.37587610
53	NELFA_20434984_ChIP-Seq_ESCs_Mouse	1.33998791
54	POU5F1_16153702_ChIP-ChIP_HESCs_Human	1.31957805
55	YY1_21170310_ChIP-Seq_MESCs_Mouse	1.30871570
56	RBPJ_22232070_ChIP-Seq_NCS_Mouse	1.27470636
57	OCT4_18692474_ChIP-Seq_MEFs_Mouse	1.26102583
58	CHD7_19251738_ChIP-ChIP_MESCs_Mouse	1.22528172
59	* SIN3B_21632747_ChIP-Seq_MESCs_Mouse	1.21705129
60	BMI1_23680149_ChIP-Seq_NPCS_Mouse	1.19959959
61	* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human	1.15788083
62	NANOG_18555785_ChIP-Seq_MESCs_Mouse	1.15410153
63	SOX2_18555785_ChIP-Seq_MESCs_Mouse	1.15199296
64	* TCF3_18692474_ChIP-Seq_MEFs_Mouse	1.13602437
65	* CTCF_18555785_ChIP-Seq_MESCs_Mouse	1.11954074
66	EBNA2_21746931_ChIP-Seq_IB4-LCL_Human	1.09293597
67	ERG_21242973_ChIP-ChIP_JURKAT_Human	1.08912186
68	SOX2_18692474_ChIP-Seq_MEFs_Mouse	1.08651563
69	HOXB4_20404135_ChIP-ChIP_EML_Mouse	1.07925331
70	ASH2L_23239880_ChIP-Seq_MESCs_Mouse	1.05253539
71	FLI1_20887958_ChIP-Seq_HPC-7_Mouse	1.04473040
72	NOTCH1_21737748_ChIP-Seq_TLL_Human	1.04328312
73	FOXP1_21924763_ChIP-Seq_HESCs_Human	1.02815890
74	NR4A2_19515692_ChIP-ChIP_MN9D_Mouse	1.02397324
75	SPI1_22096565_ChIP-ChIP_GC-B_Mouse	1.01888478
76	KDM5A_27292631_Chip-Seq_BREAST_Human	1.00705416
77	THAP11_20581084_ChIP-Seq_MESCs_Mouse	1.00301947
78	POU5F1_18555785_ChIP-Seq_MESCs_Mouse	0.99863593
79	TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse	0.99635675
80	TP63_19390658_ChIP-ChIP_HaCaT_Human	0.99027642
81	RBPJ_21746931_ChIP-Seq_IB4-LCL_Human	0.97929059
82	* KLF4_18358816_ChIP-ChIP_MESCs_Mouse	0.96711685
83	PDX1_19855005_ChIP-ChIP_MIN6_Mouse	0.96019520
84	CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human	0.95410031
85	TET1_21451524_ChIP-Seq_MESCs_Mouse	0.94427072
86	JARID2_20064375_ChIP-Seq_MESCs_Mouse	0.93938349
87	* NANOG_18692474_ChIP-Seq_MEFs_Mouse	0.91227976
88	SRF_21415370_ChIP-Seq_HL-1_Mouse	0.90314236
89	* CTCF_26484167_Chip-Seq_Bcells_Mouse	0.89596099
90	STAT1_20625510_ChIP-Seq_HELA_Human	0.88527653
91	VDR_22108803_ChIP-Seq_LS180_Human	0.87980444
92	ERG_20887958_ChIP-Seq_HPC-7_Mouse	0.87230442
93	MYCN_21190229_ChIP-Seq_SHEP-21N_Human	0.86388495
94	SIN3A_21632747_ChIP-Seq_MESCs_Mouse	0.86004244
95	P63_26484246_Chip-Seq_KERATINOCYTES_Human	0.85822552
96	SPI1_23547873_ChIP-Seq_NB4_Human	0.84281206
97	NANOG_16153702_ChIP-ChIP_HESCs_Human	0.82567599
98	* VDR_21846776_ChIP-Seq_THP-1_Human	0.82452426
99	E2F1_21310950_ChIP-Seq_MCF-7_Human	0.81847505
100	CBX2_27304074_Chip-Seq_ESCs_Mouse	0.81772119
101	SA1_27219007_Chip-Seq_Bcells_Human	0.81614426
102	EED_16625203_ChIP-ChIP_MESCs_Mouse	0.81530139
103	PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse	0.81141466
104	EWS_26573619_Chip-Seq_HEK293_Human	0.80256008
105	YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse	0.80223159
106	SUZ12_27294783_Chip-Seq_ESCs_Mouse	0.79651291
107	RNF2_27304074_Chip-Seq_NSC_Mouse	0.79148687
108	* SOX2_16153702_ChIP-ChIP_HESCs_Human	0.79011890
109	ERG_20517297_ChIP-Seq_VCAP_Human	0.78629283
110	EZH2_27294783_Chip-Seq_ESCs_Mouse	0.78591933
111	BCL3_23251550_ChIP-Seq_MUSCLE_Mouse	0.78562628
112	TRIM28_21343339_ChIP-Seq_HEK293_Human	0.78136657
113	EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human	0.78078840
114	SOX2_19030024_ChIP-ChIP_MESCs_Mouse	0.78031319
115	SMAD4_19686287_ChIP-ChIP_HaCaT_Human	0.77951090
116	TP53_20018659_ChIP-ChIP_R1E_Mouse	0.77847487
117	NANOG_20526341_ChIP-Seq_ESCs_Human	0.77333507
118	HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse	0.77084628
119	HNF4A_19761587_ChIP-ChIP_CACO-2_Human	0.77076690
120	* TAF2_19829295_ChIP-Seq_ESCs_Human	0.76893200
121	FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse	0.75184743
122	IKZF1_21737484_ChIP-ChIP_HCT116_Human	0.75083295
123	IRF8_22096565_ChIP-ChIP_GC-B_Mouse	0.74032111
124	GABP_19822575_ChIP-Seq_HepG2_Human	0.74017351
125	PHC1_16625203_ChIP-ChIP_MESCs_Mouse	0.73978794
126	MAF_26560356_Chip-Seq_TH2_Human	0.73184887
127	SOX17_20123909_ChIP-Seq_XEN_Mouse	0.71376310
128	CNOT3_19339689_ChIP-ChIP_MESCs_Mouse	0.70837533
129	SCL_19346495_ChIP-Seq_HPC-7_Human	0.69581766
130	YY1_22570637_ChIP-Seq_MALME-3M_Human	0.66041137
131	EZH2_27304074_Chip-Seq_ESCs_Mouse	0.65304995

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0009379_abnormal_foot_pigmentation	9.27129578
2	MP0004381_abnormal_hair_follicle	4.12451557
3	MP0003136_yellow_coat_color	3.76999282
4	MP0003941_abnormal_skin_development	3.07413544
5	MP0005409_darkened_coat_color	2.60118871
6	MP0000566_synostosis	2.47347625
7	MP0002796_impaired_skin_barrier	2.35210334
8	MP0002653_abnormal_ependyma_morphology	2.22851480
9	MP0002638_abnormal_pupillary_reflex	2.13679377
10	MP0002938_white_spotting	1.99321553
11	MP0002148_abnormal_hypersensitivity_rea	1.96162376
12	MP0002102_abnormal_ear_morphology	1.86905186
13	MP0005174_abnormal_tail_pigmentation	1.81795119
14	MP0001293_anophthalmia	1.80237977
15	MP0001727_abnormal_embryo_implantation	1.69392239
16	MP0001346_abnormal_lacrimal_gland	1.64105601
17	MP0002277_abnormal_respiratory_mucosa	1.63926055
18	MP0003011_delayed_dark_adaptation	1.59826881
19	MP0008995_early_reproductive_senescence	1.59231463
20	MP0003938_abnormal_ear_development	1.58723531
21	MP0003315_abnormal_perineum_morphology	1.57061012
22	MP0000372_irregular_coat_pigmentation	1.54283923
23	MP0000631_abnormal_neuroendocrine_gland	1.52184436
24	MP0005394_taste/olfaction_phenotype	1.51297852
25	MP0005499_abnormal_olfactory_system	1.51297852
26	MP0004957_abnormal_blastocyst_morpholog	1.50392504
27	MP0001485_abnormal_pinna_reflex	1.49874235
28	MP0003880_abnormal_central_pattern	1.49400169
29	MP0002163_abnormal_gland_morphology	1.47387840
30	MP0002098_abnormal_vibrissa_morphology	1.47283596
31	MP0000762_abnormal_tongue_morphology	1.46760936
32	MP0001879_abnormal_lymphatic_vessel	1.46592312
33	MP0003693_abnormal_embryo_hatching	1.43033995
34	MP0008057_abnormal_DNA_replication	1.42173765
35	MP0005501_abnormal_skin_physiology	1.40919219
36	MP0005377_hearing/vestibular/ear_phenot	1.38580376
37	MP0003878_abnormal_ear_physiology	1.38580376
38	MP0004742_abnormal_vestibular_system	1.34146785
39	MP0005408_hypopigmentation	1.34093471
40	MP0003786_premature_aging	1.30837578
41	MP0000647_abnormal_sebaceous_gland	1.30097823
42	MP0000383_abnormal_hair_follicle	1.29084106
43	MP0002132_abnormal_respiratory_system	1.28234406
44	MP0002249_abnormal_larynx_morphology	1.28038997
45	MP0005423_abnormal_somatic_nervous	1.25369602
46	MP0003186_abnormal_redox_activity	1.24940086
47	MP0001905_abnormal_dopamine_level	1.24342299
48	MP0002095_abnormal_skin_pigmentation	1.24239616
49	MP0001851_eye_inflammation	1.23788298
50	MP0000026_abnormal_inner_ear	1.23146791
51	MP0003283_abnormal_digestive_organ	1.22985515
52	MP0002254_reproductive_system_inflammat	1.22515911
53	MP0005379_endocrine/exocrine_gland_phen	1.21336909
54	MP0009333_abnormal_splenocyte_physiolog	1.20870422
55	MP0008932_abnormal_embryonic_tissue	1.19726558
56	MP0006292_abnormal_olfactory_placode	1.19582034
57	MP0001286_abnormal_eye_development	1.19460671
58	MP0001853_heart_inflammation	1.16567753
59	MP0000049_abnormal_middle_ear	1.15831451
60	MP0005083_abnormal_biliary_tract	1.15762618
61	MP0003763_abnormal_thymus_physiology	1.15630639
62	MP0005084_abnormal_gallbladder_morpholo	1.15412144
63	MP0003724_increased_susceptibility_to	1.13636428
64	MP0005075_abnormal_melanosome_morpholog	1.12135980
65	MP0003122_maternal_imprinting	1.12047474
66	MP0002160_abnormal_reproductive_system	1.11424681
67	MP0001800_abnormal_humoral_immune	1.10897573
68	MP0002282_abnormal_trachea_morphology	1.10730793
69	MP0005000_abnormal_immune_tolerance	1.09541886
70	MP0003123_paternal_imprinting	1.09292554
71	MP0003718_maternal_effect	1.08099441
72	MP0000778_abnormal_nervous_system	1.06644411
73	MP0000465_gastrointestinal_hemorrhage	1.05571313
74	MP0001216_abnormal_epidermal_layer	1.04993848
75	MP0006072_abnormal_retinal_apoptosis	1.04347489
76	MP0001188_hyperpigmentation	1.04289100
77	MP0010771_integument_phenotype	1.03003824
78	MP0006276_abnormal_autonomic_nervous	1.00179558
79	MP0005389_reproductive_system_phenotype	0.99281732
80	MP0002822_catalepsy	0.98669055
81	MP0001919_abnormal_reproductive_system	0.97590711
82	MP0005671_abnormal_response_to	0.97396525
83	MP0002405_respiratory_system_inflammati	0.97102478
84	MP0000750_abnormal_muscle_regeneration	0.95970496
85	MP0005551_abnormal_eye_electrophysiolog	0.95491162
86	MP0005195_abnormal_posterior_eye	0.95372343
87	MP0003638_abnormal_response/metabolism_	0.95043454
88	MP0002060_abnormal_skin_morphology	0.94562226
89	MP0005025_abnormal_response_to	0.94362936
90	MP0001986_abnormal_taste_sensitivity	0.93956868
91	MP0003436_decreased_susceptibility_to	0.92781733
92	MP0001529_abnormal_vocalization	0.92371565
93	MP0002234_abnormal_pharynx_morphology	0.92087201
94	MP0002697_abnormal_eye_size	0.91709504
95	MP0002723_abnormal_immune_serum	0.91619311
96	MP0003077_abnormal_cell_cycle	0.90583396
97	MP0003806_abnormal_nucleotide_metabolis	0.90203388
98	MP0008058_abnormal_DNA_repair	0.89951668
99	MP0010678_abnormal_skin_adnexa	0.89402681
100	MP0004885_abnormal_endolymph	0.88515165
101	MP0002420_abnormal_adaptive_immunity	0.87646933
102	MP0003121_genomic_imprinting	0.87433628
103	MP0002452_abnormal_antigen_presenting	0.86437429
104	MP0002210_abnormal_sex_determination	0.86407807
105	MP0001835_abnormal_antigen_presentation	0.86315324
106	MP0002752_abnormal_somatic_nervous	0.85408365
107	MP0003787_abnormal_imprinting	0.85296178
108	MP0001819_abnormal_immune_cell	0.85073454
109	MP0001663_abnormal_digestive_system	0.84658050
110	MP0000703_abnormal_thymus_morphology	0.84339019
111	MP0002928_abnormal_bile_duct	0.83183822
112	MP0009053_abnormal_anal_canal	0.82207747
113	MP0000467_abnormal_esophagus_morphology	0.81702922
114	MP0009785_altered_susceptibility_to	0.79364930
115	MP0001873_stomach_inflammation	0.78902498
116	MP0004147_increased_porphyrin_level	0.77755751
117	MP0003890_abnormal_embryonic-extraembry	0.76898900
118	MP0000685_abnormal_immune_system	0.76858203
119	MP0002722_abnormal_immune_system	0.76037467
120	MP0000490_abnormal_crypts_of	0.75867555
121	MP0008875_abnormal_xenobiotic_pharmacok	0.74602214
122	MP0000377_abnormal_hair_follicle	0.74301932
123	MP0008877_abnormal_DNA_methylation	0.73139914
124	MP0001340_abnormal_eyelid_morphology	0.70842042
125	MP0005164_abnormal_response_to	0.70679917
126	MP0002736_abnormal_nociception_after	0.70654585
127	MP0004145_abnormal_muscle_electrophysio	0.70323228
128	MP0005391_vision/eye_phenotype	0.69999537
129	MP0001790_abnormal_immune_system	0.69245132
130	MP0005387_immune_system_phenotype	0.69245132
131	MP0001963_abnormal_hearing_physiology	0.69155647
132	MP0005381_digestive/alimentary_phenotyp	0.68393201
133	MP0001968_abnormal_touch/_nociception	0.67832338
134	MP0002751_abnormal_autonomic_nervous	0.67821464
135	MP0002233_abnormal_nose_morphology	0.67554057
136	MP0004142_abnormal_muscle_tone	0.66709488
137	MP0008872_abnormal_physiological_respon	0.66454739
138	MP0002009_preneoplasia	0.66372782
139	MP0001324_abnormal_eye_pigmentation	0.66253434
140	MP0002557_abnormal_social/conspecific_i	0.66142516
141	MP0005253_abnormal_eye_physiology	0.65930803
142	MP0002837_dystrophic_cardiac_calcinosis	0.65893472
143	MP0003453_abnormal_keratinocyte_physiol	0.65774192
144	MP0000537_abnormal_urethra_morphology	0.65477328
145	MP0010030_abnormal_orbit_morphology	0.65438699
146	MP0008789_abnormal_olfactory_epithelium	0.64939949
147	MP0009250_abnormal_appendicular_skeleto	0.64869918
148	MP0002166_altered_tumor_susceptibility	0.64852850
149	MP0002398_abnormal_bone_marrow	0.64065529
150	MP0003567_abnormal_fetal_cardiomyocyte	0.64036967
151	MP0005645_abnormal_hypothalamus_physiol	0.63968021
152	MP0000613_abnormal_salivary_gland	0.63287885
153	MP0000716_abnormal_immune_system	0.63049069
154	MP0005451_abnormal_body_composition	0.63000643
155	MP0000955_abnormal_spinal_cord	0.62139637
156	MP0002177_abnormal_outer_ear	0.62084835
157	MP0004133_heterotaxia	0.61969228
158	MP0009745_abnormal_behavioral_response	0.61881325
159	MP0002272_abnormal_nervous_system	0.61492857
160	MP0003119_abnormal_digestive_system	0.61466136
161	MP0002006_tumorigenesis	0.61262602
162	MP0002184_abnormal_innervation	0.60913434

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Reticulocytopenia (HP:0001896)	9.71638067
2	* Macrocytic anemia (HP:0001972)	7.17147015
3	* Pallor (HP:0000980)	6.18086944
4	Abnormality of secondary sexual hair (HP:0009888)	4.50469490
5	Abnormality of the axillary hair (HP:0100134)	4.50469490
6	Congenital, generalized hypertrichosis (HP:0004540)	4.15890578
7	Increased hepatocellular lipid droplets (HP:0006565)	4.04834127
8	Acute necrotizing encephalopathy (HP:0006965)	4.02965328
9	Parakeratosis (HP:0001036)	3.92220792
10	Septo-optic dysplasia (HP:0100842)	3.76202899
11	Congenital nonbullous ichthyosiform erythroderma (HP:0007479)	3.75085622
12	Aplasia/Hypoplasia of the sacrum (HP:0008517)	3.69205518
13	Mitochondrial inheritance (HP:0001427)	3.66509304
14	Abnormal hemoglobin (HP:0011902)	3.57667477
15	Renal Fanconi syndrome (HP:0001994)	3.46491780
16	Progressive macrocephaly (HP:0004481)	3.45147723
17	Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)	3.39494992
18	Lipid accumulation in hepatocytes (HP:0006561)	3.38040433
19	Abnormal mitochondria in muscle tissue (HP:0008316)	3.29839376
20	Stenosis of the external auditory canal (HP:0000402)	3.28056155
21	Muscle abnormality related to mitochondrial dysfunction (HP:0003800)	3.09218290
22	Exertional dyspnea (HP:0002875)	3.08817978
23	Woolly hair (HP:0002224)	2.97231393
24	Abnormality of reticulocytes (HP:0004312)	2.91214478
25	Acute encephalopathy (HP:0006846)	2.90334805
26	Congenital ichthyosiform erythroderma (HP:0007431)	2.84835991
27	* Depressed nasal ridge (HP:0000457)	2.84572416
28	Concave nail (HP:0001598)	2.83743929
29	Partial duplication of thumb phalanx (HP:0009944)	2.83329401
30	3-Methylglutaconic aciduria (HP:0003535)	2.79518383
31	Increased CSF lactate (HP:0002490)	2.74819348
32	Asplenia (HP:0001746)	2.74150345
33	Respiratory difficulties (HP:0002880)	2.70797538
34	Partial duplication of the phalanx of hand (HP:0009999)	2.68427773
35	Hepatocellular necrosis (HP:0001404)	2.63446092
36	* Migraine (HP:0002076)	2.62102674
37	Maternal diabetes (HP:0009800)	2.59591911
38	Rib fusion (HP:0000902)	2.53992744
39	Abnormal activity of mitochondrial respiratory chain (HP:0011922)	2.53034063
40	Decreased activity of mitochondrial respiratory chain (HP:0008972)	2.53034063
41	Aplastic anemia (HP:0001915)	2.52818006
42	Increased intramyocellular lipid droplets (HP:0012240)	2.52347195
43	Aplasia/Hypoplasia of the spleen (HP:0010451)	2.47021364
44	Abnormality of midbrain morphology (HP:0002418)	2.44137201
45	Molar tooth sign on MRI (HP:0002419)	2.44137201
46	Absent thumb (HP:0009777)	2.41970873
47	Myokymia (HP:0002411)	2.39964701
48	Absent septum pellucidum (HP:0001331)	2.39658869
49	Pancreatic cysts (HP:0001737)	2.39227711
50	11 pairs of ribs (HP:0000878)	2.37794468
51	Hypotrichosis (HP:0001006)	2.36525956
52	Pancreatic fibrosis (HP:0100732)	2.35834803
53	Fragile nails (HP:0001808)	2.29951191
54	Optic disc pallor (HP:0000543)	2.20266088
55	* Thick lower lip vermilion (HP:0000179)	2.19372541
56	Hepatic necrosis (HP:0002605)	2.15864675
57	True hermaphroditism (HP:0010459)	2.14673801
58	Colon cancer (HP:0003003)	2.14057548
59	Aplasia cutis congenita (HP:0001057)	2.12734405
60	Abnormality of placental membranes (HP:0011409)	2.09043647
61	Amniotic constriction ring (HP:0009775)	2.09043647
62	Hypoplasia of the radius (HP:0002984)	2.08794233
63	Absent hand (HP:0004050)	2.07946568
64	Hypoproteinemia (HP:0003075)	2.07817251
65	Abnormality of renal resorption (HP:0011038)	2.04385744
66	Increased serum lactate (HP:0002151)	2.01375966
67	Triphalangeal thumb (HP:0001199)	2.00245846
68	Abnormality of cells of the erythroid lineage (HP:0012130)	11.7376173
69	Abnormal number of erythroid precursors (HP:0012131)	10.4816078
70	Oral leukoplakia (HP:0002745)	1.99320000
71	Trismus (HP:0000211)	1.99191795
72	Anophthalmia (HP:0000528)	1.96754079
73	Sclerocornea (HP:0000647)	1.96249649
74	Exercise intolerance (HP:0003546)	1.94805767
75	Thrombocytosis (HP:0001894)	1.94054247
76	Esophageal atresia (HP:0002032)	1.93476742
77	Increased muscle lipid content (HP:0009058)	1.90502585
78	Duplication of thumb phalanx (HP:0009942)	1.88871597
79	Nephronophthisis (HP:0000090)	1.88637373
80	Optic nerve hypoplasia (HP:0000609)	1.88263729
81	Congenital stationary night blindness (HP:0007642)	1.88256590
82	Mesangial abnormality (HP:0001966)	1.85846263
83	Seborrheic dermatitis (HP:0001051)	1.85587157
84	Erythroderma (HP:0001019)	1.85118570
85	Abnormal number of incisors (HP:0011064)	1.85105994
86	Respiratory failure (HP:0002878)	1.83689040
87	Multiple enchondromatosis (HP:0005701)	1.78836416
88	Sparse eyelashes (HP:0000653)	1.77695782
89	Leukodystrophy (HP:0002415)	1.76329156
90	Absent radius (HP:0003974)	1.76302312
91	Absent rod-and cone-mediated responses on ERG (HP:0007688)	1.75993330
92	Aplasia/Hypoplasia of the optic nerve (HP:0008058)	1.74542763
93	Hyperglycinemia (HP:0002154)	1.73001371
94	Cleft eyelid (HP:0000625)	1.72763791
95	Abnormal ciliary motility (HP:0012262)	1.72719133
96	Absent hair (HP:0002298)	1.72695120
97	Bilateral microphthalmos (HP:0007633)	1.72322674
98	Lethargy (HP:0001254)	1.72288897
99	Abnormal respiratory motile cilium physiology (HP:0012261)	1.70694695
100	Abnormal rod and cone electroretinograms (HP:0008323)	1.68554958
101	Medial flaring of the eyebrow (HP:0010747)	1.67995827
102	Abnormal urine phosphate concentration (HP:0012599)	1.67560319
103	Nasolacrimal duct obstruction (HP:0000579)	1.67345825
104	Abnormality of the phalanges of the 2nd finger (HP:0009541)	1.67250577
105	Cerebral edema (HP:0002181)	1.67231871
106	Pendular nystagmus (HP:0012043)	1.66334631
107	Forearm undergrowth (HP:0009821)	1.65844941
108	Anencephaly (HP:0002323)	1.65538623
109	Hypoplasia of the pons (HP:0012110)	1.65397801
110	Carpal bone hypoplasia (HP:0001498)	1.64813682
111	Aplasia involving forearm bones (HP:0009822)	1.64781896
112	Absent forearm bone (HP:0003953)	1.64781896
113	Conical tooth (HP:0000698)	1.63701000
114	Horseshoe kidney (HP:0000085)	1.63407840
115	Glossoptosis (HP:0000162)	1.63144255
116	Onycholysis (HP:0001806)	1.62648000
117	Pancytopenia (HP:0001876)	1.62537304
118	Aplasia/Hypoplasia of the ulna (HP:0006495)	1.62511290
119	Abnormal respiratory motile cilium morphology (HP:0005938)	1.62175717
120	Abnormal respiratory epithelium morphology (HP:0012253)	1.62175717
121	Type II lissencephaly (HP:0007260)	1.60947933
122	Sparse lateral eyebrow (HP:0005338)	1.59595915
123	Hypoplasia of the ulna (HP:0003022)	1.59201487
124	Type 2 muscle fiber atrophy (HP:0003554)	1.57858601
125	Aplasia/hypoplasia of the uterus (HP:0008684)	1.56411812
126	Abnormality of the parietal bone (HP:0002696)	1.53818976
127	Hyperphosphaturia (HP:0003109)	1.52471735
128	Abnormality of the septum pellucidum (HP:0007375)	1.50129001
129	Abnormal pupillary function (HP:0007686)	1.50077606
130	IgM deficiency (HP:0002850)	1.49652887
131	Panhypogammaglobulinemia (HP:0003139)	1.49408606
132	Neonatal respiratory distress (HP:0002643)	1.48439921
133	Plantar hyperkeratosis (HP:0007556)	1.44176465
134	Chin dimple (HP:0010751)	1.43516212
135	Ridged nail (HP:0001807)	1.42777391
136	Septate vagina (HP:0001153)	1.42613732
137	* Short nose (HP:0003196)	1.42254547
138	Breast hypoplasia (HP:0003187)	1.40017479
139	Abnormality of urine glucose concentration (HP:0011016)	1.38587720
140	Glycosuria (HP:0003076)	1.38587720
141	Lactic acidosis (HP:0003128)	1.37311374

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	NME2	6.50970095
2	VRK2	4.88422555
3	MST4	3.18334041
4	TLK1	3.05561580
5	LRRK2	2.97742166
6	BUB1	2.93405318
7	STK16	2.64168349
8	CDC7	2.59260329
9	RPS6KB2	2.48636379
10	ZAK	2.36458879
11	BLK	2.33797412
12	VRK1	2.31565291
13	WEE1	2.21650037
14	SRPK1	2.18910937
15	KDR	2.12716557
16	PIM2	1.71377536
17	TGFBR1	1.67448932
18	NME1	1.63680398
19	MAP3K3	1.60125175
20	BCKDK	1.55771783
21	CDK19	1.49399637
22	BMPR1B	1.45133528
23	MAPKAPK5	1.45011097
24	TXK	1.44218358
25	ILK	1.40537760
26	WNK4	1.38892211
27	EEF2K	1.34819019
28	TAF1	1.32650150
29	MAPKAPK3	1.30766294
30	MAP3K11	1.28948730
31	MAP4K1	1.26720054
32	PBK	1.19406152
33	DYRK2	1.17945364
34	GRK7	1.17742644
35	DYRK3	1.16297279
36	PKN1	1.13200969
37	PNCK	1.12947763
38	UHMK1	1.12543615
39	INSRR	1.11867356
40	TYRO3	1.09967201
41	MAP2K2	1.07125221
42	STK39	1.03036111
43	MAPK15	1.02104462
44	ADRBK1	1.01517412
45	NEK2	1.00720467
46	ARAF	0.98667351
47	WNK3	0.95346419
48	EPHB2	0.94098712
49	CLK1	0.93970276
50	BTK	0.93281277
51	ADRBK2	0.92928653
52	GRK1	0.91503909
53	DAPK3	0.91458457
54	MKNK1	0.89714462
55	AURKB	0.88696528
56	NUAK1	0.88491335
57	FES	0.84994484
58	AURKA	0.82780958
59	EIF2AK2	0.80637314
60	TAOK3	0.80602692
61	CASK	0.79301950
62	FGR	0.79176200
63	RPS6KA5	0.79064155
64	CHEK2	0.78592272
65	MUSK	0.78410301
66	TNIK	0.77913646
67	CSNK2A2	0.77554679
68	MYLK	0.77390866
69	EIF2AK3	0.77280396
70	IRAK2	0.76064208
71	IKBKB	0.75994722
72	PRKCG	0.73590760
73	STK11	0.72992004
74	RPS6KA6	0.72975690
75	MST1R	0.72041516
76	TEC	0.71444271
77	MAPK4	0.71148515
78	PIK3CA	0.70224091
79	SYK	0.68445717
80	ROCK2	0.67324234
81	LYN	0.66840769
82	PASK	0.66549902
83	CDK7	0.66528140
84	PTK6	0.63650193
85	IRAK4	0.63528794
86	ABL2	0.63243495
87	STK10	0.63103620
88	MAP2K7	0.62775869
89	YES1	0.62320863
90	CSNK2A1	0.62213885
91	LCK	0.61528557
92	ITK	0.61070245
93	TIE1	0.59935044
94	MAP3K12	0.59464383
95	PAK1	0.59189190
96	MOS	0.56882561
97	PRKCQ	0.56740285
98	IKBKE	0.55041566
99	PAK2	0.54519334
100	NLK	0.54460351
101	BRAF	0.53763172
102	PIK3CG	0.51958279
103	MARK3	0.51880678
104	RPS6KC1	0.51665897
105	RPS6KL1	0.51665897
106	MAPK13	0.50269317
107	MAP3K10	0.49587380
108	TGFBR2	0.47616161
109	CAMKK1	0.47458506
110	EPHA2	0.47047900
111	FGFR2	0.46470472
112	DYRK1B	0.46018835
113	CDK4	0.45424592
114	ATR	0.44971130
115	PRKACA	0.44819312
116	PRKCD	0.44533156
117	MAPK12	0.44119108
118	CAMK1	0.42527225
119	CDK3	0.42064221
120	BRSK2	0.41083241
121	CDK8	0.41046235
122	OXSR1	0.40015397
123	KIT	0.39973827
124	GRK6	0.39428465
125	TYK2	0.38771575
126	PLK1	0.37432436
127	NTRK2	0.36360577
128	PLK4	0.36186542
129	MAPKAPK2	0.35750686
130	TESK2	0.35104820
131	MAP2K3	0.34941068
132	MAP3K9	0.34160737
133	PINK1	0.33428931
134	PIM1	0.33108678
135	CSNK1E	0.32592398
136	STK24	0.32575168
137	ACVR1B	0.32285180
138	PRKD1	0.32155042
139	GRK5	0.32078058
140	CAMKK2	0.30294989

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Oxidative phosphorylation_Homo sapiens_hsa00190	4.06439640
2	Parkinsons disease_Homo sapiens_hsa05012	3.47062665
3	Proteasome_Homo sapiens_hsa03050	2.82819618
4	RNA polymerase_Homo sapiens_hsa03020	2.82440278
5	Alzheimers disease_Homo sapiens_hsa05010	2.66465899
6	Huntingtons disease_Homo sapiens_hsa05016	2.60503361
7	Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932	2.38754391
8	Spliceosome_Homo sapiens_hsa03040	2.30562170
9	Protein export_Homo sapiens_hsa03060	2.24042887
10	* Ribosome_Homo sapiens_hsa03010	10.3142496
11	DNA replication_Homo sapiens_hsa03030	1.85594108
12	Mismatch repair_Homo sapiens_hsa03430	1.68174856
13	Pyrimidine metabolism_Homo sapiens_hsa00240	1.61721254
14	Cardiac muscle contraction_Homo sapiens_hsa04260	1.58292115
15	Homologous recombination_Homo sapiens_hsa03440	1.39647260
16	Nucleotide excision repair_Homo sapiens_hsa03420	1.37126900
17	Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008	1.22740792
18	Primary immunodeficiency_Homo sapiens_hsa05340	1.17672038
19	Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623	1.14741640
20	Arachidonic acid metabolism_Homo sapiens_hsa00590	1.05452387
21	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	1.04886928
22	Cyanoamino acid metabolism_Homo sapiens_hsa00460	1.02183821
23	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563	0.98547048
24	Non-homologous end-joining_Homo sapiens_hsa03450	0.96438375
25	RNA transport_Homo sapiens_hsa03013	0.90537183
26	RNA degradation_Homo sapiens_hsa03018	0.87533758
27	Systemic lupus erythematosus_Homo sapiens_hsa05322	0.81713555
28	Base excision repair_Homo sapiens_hsa03410	0.79342702
29	Fanconi anemia pathway_Homo sapiens_hsa03460	0.79272091
30	Graft-versus-host disease_Homo sapiens_hsa05332	0.78964872
31	Basal transcription factors_Homo sapiens_hsa03022	0.77380812
32	Folate biosynthesis_Homo sapiens_hsa00790	0.76817520
33	Hematopoietic cell lineage_Homo sapiens_hsa04640	0.76347472
34	Glutathione metabolism_Homo sapiens_hsa00480	0.72062713
35	Asthma_Homo sapiens_hsa05310	0.69955655
36	Purine metabolism_Homo sapiens_hsa00230	0.69858854
37	Allograft rejection_Homo sapiens_hsa05330	0.69777654
38	Vitamin digestion and absorption_Homo sapiens_hsa04977	0.69083260
39	SNARE interactions in vesicular transport_Homo sapiens_hsa04130	0.68396139
40	Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060	0.68334561
41	Maturity onset diabetes of the young_Homo sapiens_hsa04950	0.67917069
42	Autoimmune thyroid disease_Homo sapiens_hsa05320	0.67627670
43	Linoleic acid metabolism_Homo sapiens_hsa00591	0.64289100
44	Epstein-Barr virus infection_Homo sapiens_hsa05169	0.62202249
45	Ether lipid metabolism_Homo sapiens_hsa00565	0.60997136
46	Phototransduction_Homo sapiens_hsa04744	0.58912130
47	Sphingolipid metabolism_Homo sapiens_hsa00600	0.58781493
48	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	0.58206547
49	p53 signaling pathway_Homo sapiens_hsa04115	0.54942284
50	Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321	0.54041169
51	One carbon pool by folate_Homo sapiens_hsa00670	0.52496974
52	Basal cell carcinoma_Homo sapiens_hsa05217	0.51490827
53	Pathogenic Escherichia coli infection_Homo sapiens_hsa05130	0.49474231
54	Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514	0.49081886
55	Nitrogen metabolism_Homo sapiens_hsa00910	0.47436600
56	Intestinal immune network for IgA production_Homo sapiens_hsa04672	0.47220808
57	Ascorbate and aldarate metabolism_Homo sapiens_hsa00053	0.46372583
58	Rheumatoid arthritis_Homo sapiens_hsa05323	0.46342539
59	Hedgehog signaling pathway_Homo sapiens_hsa04340	0.45301016
60	Fat digestion and absorption_Homo sapiens_hsa04975	0.44140956
61	Fatty acid elongation_Homo sapiens_hsa00062	0.43829499
62	Nicotine addiction_Homo sapiens_hsa05033	0.43378535
63	Transcriptional misregulation in cancer_Homo sapiens_hsa05202	0.42408224
64	Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603	0.39289961
65	NOD-like receptor signaling pathway_Homo sapiens_hsa04621	0.39267743
66	Steroid hormone biosynthesis_Homo sapiens_hsa00140	0.37152944
67	Cell cycle_Homo sapiens_hsa04110	0.36925244
68	Tryptophan metabolism_Homo sapiens_hsa00380	0.36864174
69	alpha-Linolenic acid metabolism_Homo sapiens_hsa00592	0.36587939
70	Retinol metabolism_Homo sapiens_hsa00830	0.36126538
71	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	0.36014960
72	Sulfur relay system_Homo sapiens_hsa04122	0.35997044
73	Peroxisome_Homo sapiens_hsa04146	0.35284844
74	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	0.35241807
75	Alcoholism_Homo sapiens_hsa05034	0.35062080
76	Type I diabetes mellitus_Homo sapiens_hsa04940	0.34544303
77	Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601	0.34041431
78	Pentose and glucuronate interconversions_Homo sapiens_hsa00040	0.32570002
79	Caffeine metabolism_Homo sapiens_hsa00232	0.32205930
80	Metabolic pathways_Homo sapiens_hsa01100	0.31742267
81	Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080	0.31690773
82	Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130	0.31140831
83	Serotonergic synapse_Homo sapiens_hsa04726	0.30966030
84	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	0.30673078
85	Drug metabolism - cytochrome P450_Homo sapiens_hsa00982	0.30649325
86	Drug metabolism - other enzymes_Homo sapiens_hsa00983	0.30320730
87	Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980	0.29948339
88	Selenocompound metabolism_Homo sapiens_hsa00450	0.29355815
89	T cell receptor signaling pathway_Homo sapiens_hsa04660	0.27972442
90	Antigen processing and presentation_Homo sapiens_hsa04612	0.26566968
91	Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533	0.26374186
92	Malaria_Homo sapiens_hsa05144	0.26242628
93	NF-kappa B signaling pathway_Homo sapiens_hsa04064	0.25160588
94	Pyruvate metabolism_Homo sapiens_hsa00620	0.25013547
95	Pathways in cancer_Homo sapiens_hsa05200	0.23614587
96	Herpes simplex infection_Homo sapiens_hsa05168	0.23032282
97	Olfactory transduction_Homo sapiens_hsa04740	0.22601262
98	Butanoate metabolism_Homo sapiens_hsa00650	0.21849691
99	Collecting duct acid secretion_Homo sapiens_hsa04966	0.21810305
100	HTLV-I infection_Homo sapiens_hsa05166	0.21705125
101	Other glycan degradation_Homo sapiens_hsa00511	0.21624449
102	Pertussis_Homo sapiens_hsa05133	0.21353709
103	Leukocyte transendothelial migration_Homo sapiens_hsa04670	0.21155386
104	Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650	0.21147722
105	Notch signaling pathway_Homo sapiens_hsa04330	0.20615171
106	Sulfur metabolism_Homo sapiens_hsa00920	0.20145545
107	Taurine and hypotaurine metabolism_Homo sapiens_hsa00430	0.18734312
108	Tyrosine metabolism_Homo sapiens_hsa00350	0.16385875
109	B cell receptor signaling pathway_Homo sapiens_hsa04662	0.16277974
110	Chemical carcinogenesis_Homo sapiens_hsa05204	0.15774653
111	Wnt signaling pathway_Homo sapiens_hsa04310	0.14906751
112	Taste transduction_Homo sapiens_hsa04742	0.14827040
113	Measles_Homo sapiens_hsa05162	0.14599163
114	Chemokine signaling pathway_Homo sapiens_hsa04062	0.13930299
115	Morphine addiction_Homo sapiens_hsa05032	0.13927088
116	Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550	0.13615732
117	Phagosome_Homo sapiens_hsa04145	0.13456756
118	TGF-beta signaling pathway_Homo sapiens_hsa04350	0.13108432
119	Axon guidance_Homo sapiens_hsa04360	0.12862902
120	Phenylalanine metabolism_Homo sapiens_hsa00360	0.11456962
121	Jak-STAT signaling pathway_Homo sapiens_hsa04630	0.11394947
122	Ras signaling pathway_Homo sapiens_hsa04014	0.10801887
123	Small cell lung cancer_Homo sapiens_hsa05222	0.10599841
124	Salmonella infection_Homo sapiens_hsa05132	0.10491839
125	ECM-receptor interaction_Homo sapiens_hsa04512	0.10438443
126	Mineral absorption_Homo sapiens_hsa04978	0.09656304
127	mRNA surveillance pathway_Homo sapiens_hsa03015	0.09476066
128	African trypanosomiasis_Homo sapiens_hsa05143	0.08969528
129	Regulation of autophagy_Homo sapiens_hsa04140	0.08528419
130	Cysteine and methionine metabolism_Homo sapiens_hsa00270	0.06866504
131	Ubiquitin mediated proteolysis_Homo sapiens_hsa04120	0.06323383
132	Glycerolipid metabolism_Homo sapiens_hsa00561	0.05388852
133	Primary bile acid biosynthesis_Homo sapiens_hsa00120	0.04002919

RPS29

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »