RPS2P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ncRNA 3-end processing (GO:0043628)7.78801304
2viral transcription (GO:0019083)7.46728912
3ribosomal small subunit assembly (GO:0000028)7.21905788
4translational termination (GO:0006415)7.04980936
5translational elongation (GO:0006414)6.04517178
6maturation of SSU-rRNA (GO:0030490)5.96395533
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.72029723
8cotranslational protein targeting to membrane (GO:0006613)5.61943087
9protein targeting to ER (GO:0045047)5.61449488
10establishment of protein localization to endoplasmic reticulum (GO:0072599)5.42413136
11cellular protein complex disassembly (GO:0043624)5.37209627
12viral life cycle (GO:0019058)5.34561718
13protein localization to endoplasmic reticulum (GO:0070972)5.31520821
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.94657232
15NADH metabolic process (GO:0006734)4.81710532
16behavioral response to nicotine (GO:0035095)4.59588744
17protein complex disassembly (GO:0043241)4.46230561
18ribonucleoprotein complex biogenesis (GO:0022613)4.40035972
19ribosomal large subunit biogenesis (GO:0042273)4.39787270
20cysteine metabolic process (GO:0006534)4.39378884
21homocysteine metabolic process (GO:0050667)4.34937048
22mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.33606746
23mitochondrial respiratory chain complex I assembly (GO:0032981)4.33606746
24NADH dehydrogenase complex assembly (GO:0010257)4.33606746
25mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.27564710
26macromolecular complex disassembly (GO:0032984)4.17735621
27translational initiation (GO:0006413)4.14713578
28positive regulation of respiratory burst (GO:0060267)4.11757507
29negative regulation of Ras GTPase activity (GO:0034261)4.06925125
30cellular component biogenesis (GO:0044085)3.91919064
31RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.89238836
32tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.89238836
33protein complex biogenesis (GO:0070271)3.71402309
34protein import into peroxisome matrix (GO:0016558)3.70077723
35protein targeting to membrane (GO:0006612)3.69644817
36phosphatidylglycerol biosynthetic process (GO:0006655)3.59996743
37RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502)3.59912809
38cell proliferation in forebrain (GO:0021846)3.53970427
39DNA deamination (GO:0045006)3.53878336
40chaperone-mediated protein transport (GO:0072321)3.49401770
41nuclear-transcribed mRNA catabolic process (GO:0000956)3.36201610
42primary alcohol catabolic process (GO:0034310)3.32585546
43phosphorylated carbohydrate dephosphorylation (GO:0046838)3.31031158
44inositol phosphate dephosphorylation (GO:0046855)3.31031158
45mitochondrial respiratory chain complex assembly (GO:0033108)3.29686508
46inositol phosphate catabolic process (GO:0071545)3.28952282
47regulation of G0 to G1 transition (GO:0070316)3.25692968
48translation (GO:0006412)3.25160621
49substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.24728376
50substrate-independent telencephalic tangential migration (GO:0021826)3.24728376
51GMP metabolic process (GO:0046037)3.24461628
52deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.22487209
53detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.21561845
54neuron fate determination (GO:0048664)3.20075937
55establishment of protein localization to mitochondrial membrane (GO:0090151)3.16104425
56pattern specification involved in kidney development (GO:0061004)3.15579346
57ATP synthesis coupled proton transport (GO:0015986)3.15221318
58energy coupled proton transport, down electrochemical gradient (GO:0015985)3.15221318
59mRNA catabolic process (GO:0006402)3.13336863
60transmission of nerve impulse (GO:0019226)3.07709275
61kidney morphogenesis (GO:0060993)2.98426152
62respiratory electron transport chain (GO:0022904)2.96223150
63electron transport chain (GO:0022900)2.95113390
64segment specification (GO:0007379)2.91337774
65positive regulation of Notch signaling pathway (GO:0045747)2.91039580
66adaptation of signaling pathway (GO:0023058)2.90284831
67intracellular protein transmembrane import (GO:0044743)2.82280847
68protein-cofactor linkage (GO:0018065)2.80920516
69positive regulation of RNA splicing (GO:0033120)2.75513315
70rRNA processing (GO:0006364)2.73448649
71sulfur amino acid catabolic process (GO:0000098)2.70025546
72RNA catabolic process (GO:0006401)2.69197418
73GTP biosynthetic process (GO:0006183)2.64155252
74somite development (GO:0061053)2.63163790
75embryonic body morphogenesis (GO:0010172)2.60756570
76rRNA metabolic process (GO:0016072)2.60664310
77establishment of protein localization to membrane (GO:0090150)2.59788344
78auditory receptor cell differentiation (GO:0042491)2.59274033
79axonal fasciculation (GO:0007413)2.57627417
80regulation of guanylate cyclase activity (GO:0031282)2.55318295
81epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.54737134
82tongue development (GO:0043586)2.54057776
83regulation of respiratory burst (GO:0060263)2.53660453
84disruption of cells of other organism (GO:0044364)2.52744935
85killing of cells of other organism (GO:0031640)2.52744935
86pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.52187184
87positive regulation of pseudopodium assembly (GO:0031274)2.50949580
88protein targeting (GO:0006605)2.50822176
89protein neddylation (GO:0045116)2.50434595
90brain morphogenesis (GO:0048854)2.47532377
91negative regulation of transcription regulatory region DNA binding (GO:2000678)2.47494424
92synaptic transmission, cholinergic (GO:0007271)2.46551980
93protein polyglutamylation (GO:0018095)2.46450448
94epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.45836628
95body morphogenesis (GO:0010171)2.45703370
96negative regulation of T cell differentiation in thymus (GO:0033085)2.44461441
97purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.43405836
98L-fucose metabolic process (GO:0042354)2.43239066
99L-fucose catabolic process (GO:0042355)2.43239066
100ribosomal small subunit biogenesis (GO:0042274)10.6544416

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.65314741
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.92997699
3E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.85495488
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.50134760
5GABP_17652178_ChIP-ChIP_JURKAT_Human2.46538760
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.01826793
7ZNF274_21170338_ChIP-Seq_K562_Hela1.98815528
8EZH2_27304074_Chip-Seq_ESCs_Mouse1.95843782
9EED_16625203_ChIP-ChIP_MESCs_Mouse1.94547398
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.89021212
11JARID2_20075857_ChIP-Seq_MESCs_Mouse1.87510746
12ERG_21242973_ChIP-ChIP_JURKAT_Human1.86358988
13EZH2_27294783_Chip-Seq_ESCs_Mouse1.77596754
14SUZ12_27294783_Chip-Seq_ESCs_Mouse1.76818045
15SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.75012502
16CBX2_27304074_Chip-Seq_ESCs_Mouse1.72802755
17BMI1_23680149_ChIP-Seq_NPCS_Mouse1.71458684
18VDR_22108803_ChIP-Seq_LS180_Human1.69941145
19SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.67820358
20ETS1_20019798_ChIP-Seq_JURKAT_Human1.63579311
21EZH2_18974828_ChIP-Seq_MESCs_Mouse1.60507458
22RNF2_18974828_ChIP-Seq_MESCs_Mouse1.60507458
23NANOG_20526341_ChIP-Seq_ESCs_Human1.57866930
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.55553689
25SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.50956863
26SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46106994
27NCOR_22424771_ChIP-Seq_293T_Human1.45478218
28CTCF_27219007_Chip-Seq_Bcells_Human1.44446717
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.44114832
30CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.38952552
31CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.38141386
32CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.38139559
33BCL6_27268052_Chip-Seq_Bcells_Human1.37061365
34MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.35501252
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35309402
36REST_21632747_ChIP-Seq_MESCs_Mouse1.33527791
37EST1_17652178_ChIP-ChIP_JURKAT_Human1.32931070
38EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.32330782
39SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.31481823
40RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.29480452
41ERA_21632823_ChIP-Seq_H3396_Human1.27994297
42TP53_22573176_ChIP-Seq_HFKS_Human1.27430269
43RNF2_27304074_Chip-Seq_ESCs_Mouse1.26696916
44BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.26332427
45TAF2_19829295_ChIP-Seq_ESCs_Human1.25698940
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.24905614
47IKZF1_21737484_ChIP-ChIP_HCT116_Human1.24359881
48MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23455909
49RNF2_27304074_Chip-Seq_NSC_Mouse1.20687368
50RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.19982496
51CTCF_20526341_ChIP-Seq_ESCs_Human1.19668040
52TP53_20018659_ChIP-ChIP_R1E_Mouse1.19500273
53FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.18262362
54GATA3_21878914_ChIP-Seq_MCF-7_Human1.16042292
55KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.14756894
56SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.14727244
57MTF2_20144788_ChIP-Seq_MESCs_Mouse1.13840267
58GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10874154
59PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.10458766
60EGR1_19032775_ChIP-ChIP_M12_Human1.10217554
61XRN2_22483619_ChIP-Seq_HELA_Human1.08771884
62EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.07459682
63PHF8_20622854_ChIP-Seq_HELA_Human1.06837928
64SA1_27219007_Chip-Seq_Bcells_Human1.06228648
65CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06000768
66SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.05981605
67EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.05162982
68FOXH1_21741376_ChIP-Seq_ESCs_Human1.04872930
69AUTS2_25519132_ChIP-Seq_293T-REX_Human1.04005147
70SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.03538527
71JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.03190641
72REST_18959480_ChIP-ChIP_MESCs_Mouse1.03061330
73MYC_18940864_ChIP-ChIP_HL60_Human1.02696429
74ETV2_25802403_ChIP-Seq_MESCs_Mouse1.02012771
75DNAJC2_21179169_ChIP-ChIP_NT2_Human1.00687691
76CTBP1_25329375_ChIP-Seq_LNCAP_Human1.00371068
77POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.00107065
78CTCF_18555785_ChIP-Seq_MESCs_Mouse0.97234740
79GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.96463937
80E2F1_20622854_ChIP-Seq_HELA_Human0.96348097
81TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95443816
82POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.95443816
83RING1B_27294783_Chip-Seq_ESCs_Mouse0.95208634
84YY1_21170310_ChIP-Seq_MESCs_Mouse0.94887229
85FUS_26573619_Chip-Seq_HEK293_Human0.93818567
86TET1_21451524_ChIP-Seq_MESCs_Mouse0.93561435
87PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.93489422
88SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92811264
89CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.92111834
90P53_21459846_ChIP-Seq_SAOS-2_Human0.91494161
91P300_27268052_Chip-Seq_Bcells_Human0.91450591
92RAD21_21589869_ChIP-Seq_MESCs_Mouse0.91355319
93DROSHA_22980978_ChIP-Seq_HELA_Human0.91116067
94P68_20966046_ChIP-Seq_HELA_Human0.90136427
95YY1_22570637_ChIP-Seq_MALME-3M_Human0.88956668
96BCOR_27268052_Chip-Seq_Bcells_Human0.88832561
97FOXH1_21741376_ChIP-Seq_EPCs_Human0.88688217
98SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88246889
99RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.87649270
100THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.87385870

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.72779588
2MP0006292_abnormal_olfactory_placode4.29478589
3MP0003879_abnormal_hair_cell3.70250473
4MP0004510_myositis3.65961593
5MP0002736_abnormal_nociception_after2.88168446
6MP0005360_urolithiasis2.80155706
7MP0001873_stomach_inflammation2.74797271
8MP0001968_abnormal_touch/_nociception2.60678747
9MP0003121_genomic_imprinting2.57424728
10MP0003123_paternal_imprinting2.29691485
11MP0004147_increased_porphyrin_level2.19094782
12MP0004885_abnormal_endolymph2.01427905
13MP0003787_abnormal_imprinting1.98723168
14MP0002938_white_spotting1.78096435
15MP0001727_abnormal_embryo_implantation1.72463708
16MP0008789_abnormal_olfactory_epithelium1.68063244
17MP0003646_muscle_fatigue1.67324399
18MP0002234_abnormal_pharynx_morphology1.65816453
19MP0000026_abnormal_inner_ear1.62741767
20MP0004142_abnormal_muscle_tone1.61785069
21MP0000631_abnormal_neuroendocrine_gland1.60223294
22MP0006082_CNS_inflammation1.59720935
23MP0005646_abnormal_pituitary_gland1.57716731
24MP0003878_abnormal_ear_physiology1.52778601
25MP0005377_hearing/vestibular/ear_phenot1.52778601
26MP0005423_abnormal_somatic_nervous1.52334195
27MP0003195_calcinosis1.49043965
28MP0000013_abnormal_adipose_tissue1.48216128
29MP0001663_abnormal_digestive_system1.47113509
30MP0001188_hyperpigmentation1.46365831
31MP0008875_abnormal_xenobiotic_pharmacok1.43606507
32MP0004742_abnormal_vestibular_system1.42433850
33MP0001986_abnormal_taste_sensitivity1.42211507
34MP0004858_abnormal_nervous_system1.41450246
35MP0002653_abnormal_ependyma_morphology1.39411175
36MP0000049_abnormal_middle_ear1.39150722
37MP0005551_abnormal_eye_electrophysiolog1.33498708
38MP0000778_abnormal_nervous_system1.32648424
39MP0004145_abnormal_muscle_electrophysio1.31150334
40MP0005174_abnormal_tail_pigmentation1.27437402
41MP0003880_abnormal_central_pattern1.26104347
42MP0006276_abnormal_autonomic_nervous1.24519220
43MP0010030_abnormal_orbit_morphology1.23718443
44MP0008004_abnormal_stomach_pH1.23578598
45MP0002933_joint_inflammation1.23120867
46MP0003122_maternal_imprinting1.21735292
47MP0002163_abnormal_gland_morphology1.21283429
48MP0005499_abnormal_olfactory_system1.20836501
49MP0005394_taste/olfaction_phenotype1.20836501
50MP0002095_abnormal_skin_pigmentation1.19823955
51MP0002734_abnormal_mechanical_nocicepti1.19195934
52MP0001905_abnormal_dopamine_level1.18626605
53MP0004019_abnormal_vitamin_homeostasis1.18318579
54MP0003938_abnormal_ear_development1.14863667
55MP0002735_abnormal_chemical_nociception1.14233981
56MP0001963_abnormal_hearing_physiology1.13199536
57MP0001485_abnormal_pinna_reflex1.11436806
58MP0001293_anophthalmia1.10293574
59MP0002102_abnormal_ear_morphology1.10283965
60MP0004133_heterotaxia1.09359991
61MP0009250_abnormal_appendicular_skeleto1.09124727
62MP0008877_abnormal_DNA_methylation1.08949701
63MP0000678_abnormal_parathyroid_gland1.07788551
64MP0001440_abnormal_grooming_behavior1.05280040
65MP0008872_abnormal_physiological_respon1.05020607
66MP0002184_abnormal_innervation1.04509594
67MP0009745_abnormal_behavioral_response1.02920663
68MP0002067_abnormal_sensory_capabilities1.00828429
69MP0005195_abnormal_posterior_eye1.00441155
70MP0002752_abnormal_somatic_nervous1.00119942
71MP0000566_synostosis0.99686600
72MP0000516_abnormal_urinary_system0.99522952
73MP0005367_renal/urinary_system_phenotyp0.99522952
74MP0005381_digestive/alimentary_phenotyp0.99276385
75MP0002272_abnormal_nervous_system0.99198629
76MP0002876_abnormal_thyroid_physiology0.98436900
77MP0002557_abnormal_social/conspecific_i0.98041599
78MP0009780_abnormal_chondrocyte_physiolo0.97218530
79MP0001970_abnormal_pain_threshold0.96489009
80MP0003136_yellow_coat_color0.93676985
81MP0005670_abnormal_white_adipose0.93584913
82MP0003635_abnormal_synaptic_transmissio0.92918612
83MP0002160_abnormal_reproductive_system0.92274462
84MP0002733_abnormal_thermal_nociception0.91449223
85MP0000955_abnormal_spinal_cord0.89701921
86MP0002572_abnormal_emotion/affect_behav0.87716391
87MP0003755_abnormal_palate_morphology0.86985869
88MP0002837_dystrophic_cardiac_calcinosis0.86864134
89MP0008775_abnormal_heart_ventricle0.78769676
90MP0000534_abnormal_ureter_morphology0.77096074
91MP0002116_abnormal_craniofacial_bone0.76920398
92MP0005085_abnormal_gallbladder_physiolo0.76381746
93MP0002063_abnormal_learning/memory/cond0.75459467
94MP0002138_abnormal_hepatobiliary_system0.75107197
95MP0002638_abnormal_pupillary_reflex0.71992311
96MP0001486_abnormal_startle_reflex0.70747588
97MP0001270_distended_abdomen0.70635283
98MP0002229_neurodegeneration0.69473202
99MP0000750_abnormal_muscle_regeneration0.68551321
100MP0000470_abnormal_stomach_morphology0.67856068

Predicted human phenotypes

RankGene SetZ-score
1Constricted visual fields (HP:0001133)6.31110771
2Abnormality of macular pigmentation (HP:0008002)6.01576121
3Reticulocytopenia (HP:0001896)5.15130639
4Metaphyseal cupping (HP:0003021)4.62437102
5Decreased electroretinogram (ERG) amplitude (HP:0000654)4.54343161
6Attenuation of retinal blood vessels (HP:0007843)4.40955811
7Abnormality of cells of the erythroid lineage (HP:0012130)4.24497197
8Cupped ribs (HP:0000887)4.15935655
9Striae distensae (HP:0001065)3.87167970
10Cone-rod dystrophy (HP:0000548)3.68002106
11Volvulus (HP:0002580)3.62741563
12Round ear (HP:0100830)3.51144658
13Macrocytic anemia (HP:0001972)3.51012698
14Abnormal number of erythroid precursors (HP:0012131)3.39074124
15Abnormality of midbrain morphology (HP:0002418)3.35761593
16Molar tooth sign on MRI (HP:0002419)3.35761593
17Congenital sensorineural hearing impairment (HP:0008527)3.26917116
18Acute necrotizing encephalopathy (HP:0006965)3.16557756
19Acute encephalopathy (HP:0006846)3.08196487
20Toxemia of pregnancy (HP:0100603)3.08099253
21Hyperglycinemia (HP:0002154)3.00779303
22Abnormality of the labia minora (HP:0012880)2.98296941
23Optic disc pallor (HP:0000543)2.97159156
24Decreased muscle mass (HP:0003199)2.90803124
25Hyperthyroidism (HP:0000836)2.79443971
26Pancreatic fibrosis (HP:0100732)2.77111966
27Abnormal mitochondria in muscle tissue (HP:0008316)2.74115181
28Progressive macrocephaly (HP:0004481)2.61688378
29Septo-optic dysplasia (HP:0100842)2.57126280
30Small hand (HP:0200055)2.49223325
31Tibial bowing (HP:0002982)2.42259934
32Mitochondrial inheritance (HP:0001427)2.40224397
33Pallor (HP:0000980)2.35353010
34Pancreatic cysts (HP:0001737)2.32679317
35Severe visual impairment (HP:0001141)2.30598392
36Chronic hepatic failure (HP:0100626)2.29494287
37Pendular nystagmus (HP:0012043)2.28660187
38Abnormal rod and cone electroretinograms (HP:0008323)2.22599804
39Absent rod-and cone-mediated responses on ERG (HP:0007688)2.20636474
40Cerebral edema (HP:0002181)2.18796143
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.15708606
42Congenital stationary night blindness (HP:0007642)2.12590637
43Aplasia/Hypoplasia of the spleen (HP:0010451)2.10928974
44Nephronophthisis (HP:0000090)2.09158538
45Type 2 muscle fiber atrophy (HP:0003554)2.08572174
46Oligodontia (HP:0000677)2.08207551
47Large earlobe (HP:0009748)2.05367934
48Maternal diabetes (HP:0009800)2.05349974
49Asplenia (HP:0001746)2.02384556
50Increased CSF lactate (HP:0002490)2.01722417
51True hermaphroditism (HP:0010459)1.99912450
52Cystic liver disease (HP:0006706)1.98916025
53Prominent supraorbital ridges (HP:0000336)1.97075926
54Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.95770943
55Abnormality of alanine metabolism (HP:0010916)1.95770943
56Hyperalaninemia (HP:0003348)1.95770943
57Broad nasal tip (HP:0000455)1.94146635
58Thyroid-stimulating hormone excess (HP:0002925)1.93325422
59Femoral bowing (HP:0002980)1.92925501
60Ovoid vertebral bodies (HP:0003300)1.92868068
61Retinitis pigmentosa (HP:0000510)1.92250079
62Chorioretinal coloboma (HP:0000567)1.90952902
63Brushfield spots (HP:0001088)1.88961421
64Concave nail (HP:0001598)1.87024152
65Tetany (HP:0001281)1.86842431
66Supernumerary spleens (HP:0009799)1.82341026
67Absent septum pellucidum (HP:0001331)1.80488231
68Rib fusion (HP:0000902)1.80082469
69Abnormality of serine family amino acid metabolism (HP:0010894)1.78819414
70Abnormality of glycine metabolism (HP:0010895)1.78819414
71Muscle fiber atrophy (HP:0100295)1.78038332
72Postnatal growth retardation (HP:0008897)1.77829674
73Hypoplastic ilia (HP:0000946)1.77496302
74Poor suck (HP:0002033)1.76300610
75Hyperglycinuria (HP:0003108)1.74281131
76Chorioretinal atrophy (HP:0000533)1.73872816
77Partial duplication of thumb phalanx (HP:0009944)1.72237532
78Hyperphosphaturia (HP:0003109)1.71870490
79Absent thumb (HP:0009777)1.70577523
80Coxa vara (HP:0002812)1.70102331
81Anencephaly (HP:0002323)1.68711005
82Aplasia/Hypoplasia of the earlobes (HP:0009906)1.67011402
83Abnormality of the renal medulla (HP:0100957)1.66432465
84Adrenal hypoplasia (HP:0000835)1.66024950
85Lethargy (HP:0001254)1.64127511
86Stenosis of the external auditory canal (HP:0000402)1.63737625
87Abnormality of magnesium homeostasis (HP:0004921)1.63662089
88Optic nerve hypoplasia (HP:0000609)1.62318373
89Akinesia (HP:0002304)1.60920999
90Agitation (HP:0000713)1.60724607
91X-linked dominant inheritance (HP:0001423)1.60202984
92Sclerocornea (HP:0000647)1.59921466
93Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.58783949
94Optic nerve coloboma (HP:0000588)1.58012057
95Abnormality of serum amino acid levels (HP:0003112)1.56200770
96Confusion (HP:0001289)1.54421939
97Abnormal respiratory motile cilium morphology (HP:0005938)1.53773094
98Abnormal respiratory epithelium morphology (HP:0012253)1.53773094
99Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.52670777
100Degeneration of the lateral corticospinal tracts (HP:0002314)1.52670777

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KIT5.39302735
2CASK3.54304156
3CDK193.51251524
4BCKDK3.12500646
5DYRK22.81174306
6WNK42.68509191
7EPHB22.66652646
8EPHA42.24217265
9ADRBK22.22301938
10TEC2.21435569
11FRK2.19002167
12FES2.16423372
13TYRO31.99495685
14TIE11.96431077
15ZAK1.91899281
16GRK11.84179461
17ACVR1B1.80422182
18NTRK31.55638705
19PIK3CA1.51214603
20MARK11.39819968
21SIK21.32064556
22IKBKB1.31567410
23CAMK1D1.26626859
24NTRK21.22608783
25LRRK21.21957624
26BMPR1B1.19379058
27NUAK11.18608224
28PINK11.17751160
29RPS6KB21.11686800
30STK391.09272949
31ADRBK11.07509958
32TLK11.06198034
33MAP4K11.04957281
34ABL21.01233458
35MAP3K111.01077678
36VRK10.99525575
37OXSR10.94396358
38PRKCG0.93113429
39STK160.90029182
40PRKCI0.89608000
41PRKCQ0.87457991
42CAMKK20.87405034
43WNK30.83518538
44PAK30.82327178
45CAMK1G0.82033445
46BRAF0.78845127
47INSRR0.78069945
48DAPK20.76681648
49CAMK10.75737430
50SYK0.72940827
51DAPK30.72939429
52SGK2230.71513085
53SGK4940.71513085
54MAPK130.70363286
55PHKG10.70101968
56PHKG20.70101968
57PRKACA0.69471284
58AKT30.66345875
59FGR0.65113225
60IKBKE0.64691514
61PIM20.61835526
62PRKCA0.58875274
63PDK20.58560198
64MAP4K20.58116340
65TXK0.56258322
66CSNK1A10.54604451
67RPS6KA60.53543545
68CSK0.53244186
69CAMK2A0.51572729
70INSR0.51446628
71JAK30.51053664
72LIMK10.49832420
73SRC0.48769968
74VRK20.47884430
75PRKCZ0.47682753
76CSNK1G30.47441162
77KDR0.45683344
78PRKACG0.44756485
79CSNK1E0.44591182
80MUSK0.43935175
81PIM10.43345424
82NEK20.43308368
83PRKCD0.42316018
84HIPK20.42086453
85CCNB10.40353930
86TAOK30.39888965
87CSNK1A1L0.39593455
88RPS6KC10.39331656
89RPS6KL10.39331656
90RPS6KA50.39171484
91DYRK1B0.38580560
92CSNK1G20.38157673
93MINK10.37341898
94OBSCN0.37213744
95MATK0.35890633
96CDK11A0.35243204
97AURKA0.34045211
98TESK20.33435167
99CSF1R0.32411299
100PRKCE0.31725035

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.00381592
2Oxidative phosphorylation_Homo sapiens_hsa001903.88465427
3Parkinsons disease_Homo sapiens_hsa050122.73807303
42-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.55325928
5Sulfur relay system_Homo sapiens_hsa041222.31323413
6Cardiac muscle contraction_Homo sapiens_hsa042602.21371460
7Fat digestion and absorption_Homo sapiens_hsa049752.14779886
8Linoleic acid metabolism_Homo sapiens_hsa005912.14186253
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.13588464
10Alzheimers disease_Homo sapiens_hsa050102.09322233
11Huntingtons disease_Homo sapiens_hsa050162.04945704
12Caffeine metabolism_Homo sapiens_hsa002322.01809558
13Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.98223062
14Sulfur metabolism_Homo sapiens_hsa009201.90677312
15Phototransduction_Homo sapiens_hsa047441.86320825
16Cyanoamino acid metabolism_Homo sapiens_hsa004601.85139025
17alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.73661665
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.68849801
19Vitamin digestion and absorption_Homo sapiens_hsa049771.60286406
20Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.57666392
21Nicotine addiction_Homo sapiens_hsa050331.56644546
22Arachidonic acid metabolism_Homo sapiens_hsa005901.47893220
23Histidine metabolism_Homo sapiens_hsa003401.44611034
24Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.41194646
25Asthma_Homo sapiens_hsa053101.39295527
26Maturity onset diabetes of the young_Homo sapiens_hsa049501.38787455
27Tryptophan metabolism_Homo sapiens_hsa003801.35924747
28Arginine and proline metabolism_Homo sapiens_hsa003301.33208170
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.32292131
30Retinol metabolism_Homo sapiens_hsa008301.30269789
31Pentose and glucuronate interconversions_Homo sapiens_hsa000401.28715384
32RNA polymerase_Homo sapiens_hsa030201.26257630
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.20734128
34Steroid hormone biosynthesis_Homo sapiens_hsa001401.19778281
35Cysteine and methionine metabolism_Homo sapiens_hsa002701.19100131
36Chemical carcinogenesis_Homo sapiens_hsa052041.16005231
37Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.09020477
38Glycerolipid metabolism_Homo sapiens_hsa005611.07529472
39One carbon pool by folate_Homo sapiens_hsa006701.00249001
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.98586914
41Intestinal immune network for IgA production_Homo sapiens_hsa046720.98572112
42Ether lipid metabolism_Homo sapiens_hsa005650.95285152
43Peroxisome_Homo sapiens_hsa041460.94860831
44Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.94533278
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.92504114
46Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.91175493
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.88536738
48Collecting duct acid secretion_Homo sapiens_hsa049660.88265638
49Arginine biosynthesis_Homo sapiens_hsa002200.84941464
50Metabolic pathways_Homo sapiens_hsa011000.82964428
51RNA degradation_Homo sapiens_hsa030180.81750647
52Pyrimidine metabolism_Homo sapiens_hsa002400.80077001
53Butanoate metabolism_Homo sapiens_hsa006500.79435475
54Olfactory transduction_Homo sapiens_hsa047400.78366513
55Morphine addiction_Homo sapiens_hsa050320.77955442
56Pyruvate metabolism_Homo sapiens_hsa006200.77820011
57Starch and sucrose metabolism_Homo sapiens_hsa005000.77635868
58Glutathione metabolism_Homo sapiens_hsa004800.74186767
59Folate biosynthesis_Homo sapiens_hsa007900.69939610
60Fatty acid degradation_Homo sapiens_hsa000710.66556398
61Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.66302879
62Serotonergic synapse_Homo sapiens_hsa047260.66025253
63Nitrogen metabolism_Homo sapiens_hsa009100.65757592
64Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.64660169
65Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62662670
66Biosynthesis of amino acids_Homo sapiens_hsa012300.59788380
67Propanoate metabolism_Homo sapiens_hsa006400.59633409
68Mineral absorption_Homo sapiens_hsa049780.59097226
69beta-Alanine metabolism_Homo sapiens_hsa004100.58273354
70Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.57067898
71Taste transduction_Homo sapiens_hsa047420.56955233
72Purine metabolism_Homo sapiens_hsa002300.56435177
73Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.55150802
74Protein export_Homo sapiens_hsa030600.52546955
75Notch signaling pathway_Homo sapiens_hsa043300.52074551
76Glycerophospholipid metabolism_Homo sapiens_hsa005640.52003929
77Fatty acid biosynthesis_Homo sapiens_hsa000610.51658191
78Glutamatergic synapse_Homo sapiens_hsa047240.50556757
79Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.47534505
80Insulin secretion_Homo sapiens_hsa049110.47423072
81Tyrosine metabolism_Homo sapiens_hsa003500.46464238
82Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.44740044
83GABAergic synapse_Homo sapiens_hsa047270.44185824
84Galactose metabolism_Homo sapiens_hsa000520.43397090
85Allograft rejection_Homo sapiens_hsa053300.41665759
86Alcoholism_Homo sapiens_hsa050340.41505928
87Autoimmune thyroid disease_Homo sapiens_hsa053200.39927626
88Bile secretion_Homo sapiens_hsa049760.39629364
89Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.39571995
90Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.39477818
91Basal transcription factors_Homo sapiens_hsa030220.38019799
92Protein digestion and absorption_Homo sapiens_hsa049740.37265192
93Circadian entrainment_Homo sapiens_hsa047130.35319990
94Selenocompound metabolism_Homo sapiens_hsa004500.35236730
95Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.35071960
96Pancreatic secretion_Homo sapiens_hsa049720.34784957
97Ovarian steroidogenesis_Homo sapiens_hsa049130.34779958
98Proteasome_Homo sapiens_hsa030500.33398932
99Homologous recombination_Homo sapiens_hsa034400.31849189
100Systemic lupus erythematosus_Homo sapiens_hsa053220.31816823

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »