

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ncRNA 3-end processing (GO:0043628) | 7.78801304 |
| 2 | viral transcription (GO:0019083) | 7.46728912 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 7.21905788 |
| 4 | translational termination (GO:0006415) | 7.04980936 |
| 5 | translational elongation (GO:0006414) | 6.04517178 |
| 6 | maturation of SSU-rRNA (GO:0030490) | 5.96395533 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.72029723 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 5.61943087 |
| 9 | protein targeting to ER (GO:0045047) | 5.61449488 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.42413136 |
| 11 | cellular protein complex disassembly (GO:0043624) | 5.37209627 |
| 12 | viral life cycle (GO:0019058) | 5.34561718 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 5.31520821 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.94657232 |
| 15 | NADH metabolic process (GO:0006734) | 4.81710532 |
| 16 | behavioral response to nicotine (GO:0035095) | 4.59588744 |
| 17 | protein complex disassembly (GO:0043241) | 4.46230561 |
| 18 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.40035972 |
| 19 | ribosomal large subunit biogenesis (GO:0042273) | 4.39787270 |
| 20 | cysteine metabolic process (GO:0006534) | 4.39378884 |
| 21 | homocysteine metabolic process (GO:0050667) | 4.34937048 |
| 22 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.33606746 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.33606746 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 4.33606746 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.27564710 |
| 26 | macromolecular complex disassembly (GO:0032984) | 4.17735621 |
| 27 | translational initiation (GO:0006413) | 4.14713578 |
| 28 | positive regulation of respiratory burst (GO:0060267) | 4.11757507 |
| 29 | negative regulation of Ras GTPase activity (GO:0034261) | 4.06925125 |
| 30 | cellular component biogenesis (GO:0044085) | 3.91919064 |
| 31 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.89238836 |
| 32 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.89238836 |
| 33 | protein complex biogenesis (GO:0070271) | 3.71402309 |
| 34 | protein import into peroxisome matrix (GO:0016558) | 3.70077723 |
| 35 | protein targeting to membrane (GO:0006612) | 3.69644817 |
| 36 | phosphatidylglycerol biosynthetic process (GO:0006655) | 3.59996743 |
| 37 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 3.59912809 |
| 38 | cell proliferation in forebrain (GO:0021846) | 3.53970427 |
| 39 | DNA deamination (GO:0045006) | 3.53878336 |
| 40 | chaperone-mediated protein transport (GO:0072321) | 3.49401770 |
| 41 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.36201610 |
| 42 | primary alcohol catabolic process (GO:0034310) | 3.32585546 |
| 43 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 3.31031158 |
| 44 | inositol phosphate dephosphorylation (GO:0046855) | 3.31031158 |
| 45 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.29686508 |
| 46 | inositol phosphate catabolic process (GO:0071545) | 3.28952282 |
| 47 | regulation of G0 to G1 transition (GO:0070316) | 3.25692968 |
| 48 | translation (GO:0006412) | 3.25160621 |
| 49 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.24728376 |
| 50 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.24728376 |
| 51 | GMP metabolic process (GO:0046037) | 3.24461628 |
| 52 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.22487209 |
| 53 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.21561845 |
| 54 | neuron fate determination (GO:0048664) | 3.20075937 |
| 55 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.16104425 |
| 56 | pattern specification involved in kidney development (GO:0061004) | 3.15579346 |
| 57 | ATP synthesis coupled proton transport (GO:0015986) | 3.15221318 |
| 58 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.15221318 |
| 59 | mRNA catabolic process (GO:0006402) | 3.13336863 |
| 60 | transmission of nerve impulse (GO:0019226) | 3.07709275 |
| 61 | kidney morphogenesis (GO:0060993) | 2.98426152 |
| 62 | respiratory electron transport chain (GO:0022904) | 2.96223150 |
| 63 | electron transport chain (GO:0022900) | 2.95113390 |
| 64 | segment specification (GO:0007379) | 2.91337774 |
| 65 | positive regulation of Notch signaling pathway (GO:0045747) | 2.91039580 |
| 66 | adaptation of signaling pathway (GO:0023058) | 2.90284831 |
| 67 | intracellular protein transmembrane import (GO:0044743) | 2.82280847 |
| 68 | protein-cofactor linkage (GO:0018065) | 2.80920516 |
| 69 | positive regulation of RNA splicing (GO:0033120) | 2.75513315 |
| 70 | rRNA processing (GO:0006364) | 2.73448649 |
| 71 | sulfur amino acid catabolic process (GO:0000098) | 2.70025546 |
| 72 | RNA catabolic process (GO:0006401) | 2.69197418 |
| 73 | GTP biosynthetic process (GO:0006183) | 2.64155252 |
| 74 | somite development (GO:0061053) | 2.63163790 |
| 75 | embryonic body morphogenesis (GO:0010172) | 2.60756570 |
| 76 | rRNA metabolic process (GO:0016072) | 2.60664310 |
| 77 | establishment of protein localization to membrane (GO:0090150) | 2.59788344 |
| 78 | auditory receptor cell differentiation (GO:0042491) | 2.59274033 |
| 79 | axonal fasciculation (GO:0007413) | 2.57627417 |
| 80 | regulation of guanylate cyclase activity (GO:0031282) | 2.55318295 |
| 81 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.54737134 |
| 82 | tongue development (GO:0043586) | 2.54057776 |
| 83 | regulation of respiratory burst (GO:0060263) | 2.53660453 |
| 84 | disruption of cells of other organism (GO:0044364) | 2.52744935 |
| 85 | killing of cells of other organism (GO:0031640) | 2.52744935 |
| 86 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.52187184 |
| 87 | positive regulation of pseudopodium assembly (GO:0031274) | 2.50949580 |
| 88 | protein targeting (GO:0006605) | 2.50822176 |
| 89 | protein neddylation (GO:0045116) | 2.50434595 |
| 90 | brain morphogenesis (GO:0048854) | 2.47532377 |
| 91 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.47494424 |
| 92 | synaptic transmission, cholinergic (GO:0007271) | 2.46551980 |
| 93 | protein polyglutamylation (GO:0018095) | 2.46450448 |
| 94 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.45836628 |
| 95 | body morphogenesis (GO:0010171) | 2.45703370 |
| 96 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.44461441 |
| 97 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.43405836 |
| 98 | L-fucose metabolic process (GO:0042354) | 2.43239066 |
| 99 | L-fucose catabolic process (GO:0042355) | 2.43239066 |
| 100 | ribosomal small subunit biogenesis (GO:0042274) | 10.6544416 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 6.65314741 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.92997699 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.85495488 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.50134760 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.46538760 |
| 6 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.01826793 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.98815528 |
| 8 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.95843782 |
| 9 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.94547398 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.89021212 |
| 11 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.87510746 |
| 12 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.86358988 |
| 13 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.77596754 |
| 14 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.76818045 |
| 15 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.75012502 |
| 16 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.72802755 |
| 17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.71458684 |
| 18 | VDR_22108803_ChIP-Seq_LS180_Human | 1.69941145 |
| 19 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.67820358 |
| 20 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.63579311 |
| 21 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.60507458 |
| 22 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.60507458 |
| 23 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.57866930 |
| 24 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.55553689 |
| 25 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.50956863 |
| 26 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.46106994 |
| 27 | NCOR_22424771_ChIP-Seq_293T_Human | 1.45478218 |
| 28 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.44446717 |
| 29 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.44114832 |
| 30 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.38952552 |
| 31 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.38141386 |
| 32 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.38139559 |
| 33 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.37061365 |
| 34 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.35501252 |
| 35 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.35309402 |
| 36 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.33527791 |
| 37 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.32931070 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.32330782 |
| 39 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.31481823 |
| 40 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.29480452 |
| 41 | ERA_21632823_ChIP-Seq_H3396_Human | 1.27994297 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27430269 |
| 43 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.26696916 |
| 44 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.26332427 |
| 45 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.25698940 |
| 46 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.24905614 |
| 47 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.24359881 |
| 48 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.23455909 |
| 49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.20687368 |
| 50 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.19982496 |
| 51 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.19668040 |
| 52 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.19500273 |
| 53 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.18262362 |
| 54 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.16042292 |
| 55 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.14756894 |
| 56 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.14727244 |
| 57 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.13840267 |
| 58 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10874154 |
| 59 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.10458766 |
| 60 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.10217554 |
| 61 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.08771884 |
| 62 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.07459682 |
| 63 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.06837928 |
| 64 | SA1_27219007_Chip-Seq_Bcells_Human | 1.06228648 |
| 65 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.06000768 |
| 66 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.05981605 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.05162982 |
| 68 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.04872930 |
| 69 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.04005147 |
| 70 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.03538527 |
| 71 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.03190641 |
| 72 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.03061330 |
| 73 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.02696429 |
| 74 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02012771 |
| 75 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.00687691 |
| 76 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.00371068 |
| 77 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00107065 |
| 78 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.97234740 |
| 79 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.96463937 |
| 80 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.96348097 |
| 81 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95443816 |
| 82 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.95443816 |
| 83 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.95208634 |
| 84 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.94887229 |
| 85 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93818567 |
| 86 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.93561435 |
| 87 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.93489422 |
| 88 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.92811264 |
| 89 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.92111834 |
| 90 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.91494161 |
| 91 | P300_27268052_Chip-Seq_Bcells_Human | 0.91450591 |
| 92 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.91355319 |
| 93 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.91116067 |
| 94 | P68_20966046_ChIP-Seq_HELA_Human | 0.90136427 |
| 95 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.88956668 |
| 96 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.88832561 |
| 97 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88688217 |
| 98 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.88246889 |
| 99 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.87649270 |
| 100 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.87385870 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.72779588 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.29478589 |
| 3 | MP0003879_abnormal_hair_cell | 3.70250473 |
| 4 | MP0004510_myositis | 3.65961593 |
| 5 | MP0002736_abnormal_nociception_after | 2.88168446 |
| 6 | MP0005360_urolithiasis | 2.80155706 |
| 7 | MP0001873_stomach_inflammation | 2.74797271 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.60678747 |
| 9 | MP0003121_genomic_imprinting | 2.57424728 |
| 10 | MP0003123_paternal_imprinting | 2.29691485 |
| 11 | MP0004147_increased_porphyrin_level | 2.19094782 |
| 12 | MP0004885_abnormal_endolymph | 2.01427905 |
| 13 | MP0003787_abnormal_imprinting | 1.98723168 |
| 14 | MP0002938_white_spotting | 1.78096435 |
| 15 | MP0001727_abnormal_embryo_implantation | 1.72463708 |
| 16 | MP0008789_abnormal_olfactory_epithelium | 1.68063244 |
| 17 | MP0003646_muscle_fatigue | 1.67324399 |
| 18 | MP0002234_abnormal_pharynx_morphology | 1.65816453 |
| 19 | MP0000026_abnormal_inner_ear | 1.62741767 |
| 20 | MP0004142_abnormal_muscle_tone | 1.61785069 |
| 21 | MP0000631_abnormal_neuroendocrine_gland | 1.60223294 |
| 22 | MP0006082_CNS_inflammation | 1.59720935 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.57716731 |
| 24 | MP0003878_abnormal_ear_physiology | 1.52778601 |
| 25 | MP0005377_hearing/vestibular/ear_phenot | 1.52778601 |
| 26 | MP0005423_abnormal_somatic_nervous | 1.52334195 |
| 27 | MP0003195_calcinosis | 1.49043965 |
| 28 | MP0000013_abnormal_adipose_tissue | 1.48216128 |
| 29 | MP0001663_abnormal_digestive_system | 1.47113509 |
| 30 | MP0001188_hyperpigmentation | 1.46365831 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.43606507 |
| 32 | MP0004742_abnormal_vestibular_system | 1.42433850 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.42211507 |
| 34 | MP0004858_abnormal_nervous_system | 1.41450246 |
| 35 | MP0002653_abnormal_ependyma_morphology | 1.39411175 |
| 36 | MP0000049_abnormal_middle_ear | 1.39150722 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.33498708 |
| 38 | MP0000778_abnormal_nervous_system | 1.32648424 |
| 39 | MP0004145_abnormal_muscle_electrophysio | 1.31150334 |
| 40 | MP0005174_abnormal_tail_pigmentation | 1.27437402 |
| 41 | MP0003880_abnormal_central_pattern | 1.26104347 |
| 42 | MP0006276_abnormal_autonomic_nervous | 1.24519220 |
| 43 | MP0010030_abnormal_orbit_morphology | 1.23718443 |
| 44 | MP0008004_abnormal_stomach_pH | 1.23578598 |
| 45 | MP0002933_joint_inflammation | 1.23120867 |
| 46 | MP0003122_maternal_imprinting | 1.21735292 |
| 47 | MP0002163_abnormal_gland_morphology | 1.21283429 |
| 48 | MP0005499_abnormal_olfactory_system | 1.20836501 |
| 49 | MP0005394_taste/olfaction_phenotype | 1.20836501 |
| 50 | MP0002095_abnormal_skin_pigmentation | 1.19823955 |
| 51 | MP0002734_abnormal_mechanical_nocicepti | 1.19195934 |
| 52 | MP0001905_abnormal_dopamine_level | 1.18626605 |
| 53 | MP0004019_abnormal_vitamin_homeostasis | 1.18318579 |
| 54 | MP0003938_abnormal_ear_development | 1.14863667 |
| 55 | MP0002735_abnormal_chemical_nociception | 1.14233981 |
| 56 | MP0001963_abnormal_hearing_physiology | 1.13199536 |
| 57 | MP0001485_abnormal_pinna_reflex | 1.11436806 |
| 58 | MP0001293_anophthalmia | 1.10293574 |
| 59 | MP0002102_abnormal_ear_morphology | 1.10283965 |
| 60 | MP0004133_heterotaxia | 1.09359991 |
| 61 | MP0009250_abnormal_appendicular_skeleto | 1.09124727 |
| 62 | MP0008877_abnormal_DNA_methylation | 1.08949701 |
| 63 | MP0000678_abnormal_parathyroid_gland | 1.07788551 |
| 64 | MP0001440_abnormal_grooming_behavior | 1.05280040 |
| 65 | MP0008872_abnormal_physiological_respon | 1.05020607 |
| 66 | MP0002184_abnormal_innervation | 1.04509594 |
| 67 | MP0009745_abnormal_behavioral_response | 1.02920663 |
| 68 | MP0002067_abnormal_sensory_capabilities | 1.00828429 |
| 69 | MP0005195_abnormal_posterior_eye | 1.00441155 |
| 70 | MP0002752_abnormal_somatic_nervous | 1.00119942 |
| 71 | MP0000566_synostosis | 0.99686600 |
| 72 | MP0000516_abnormal_urinary_system | 0.99522952 |
| 73 | MP0005367_renal/urinary_system_phenotyp | 0.99522952 |
| 74 | MP0005381_digestive/alimentary_phenotyp | 0.99276385 |
| 75 | MP0002272_abnormal_nervous_system | 0.99198629 |
| 76 | MP0002876_abnormal_thyroid_physiology | 0.98436900 |
| 77 | MP0002557_abnormal_social/conspecific_i | 0.98041599 |
| 78 | MP0009780_abnormal_chondrocyte_physiolo | 0.97218530 |
| 79 | MP0001970_abnormal_pain_threshold | 0.96489009 |
| 80 | MP0003136_yellow_coat_color | 0.93676985 |
| 81 | MP0005670_abnormal_white_adipose | 0.93584913 |
| 82 | MP0003635_abnormal_synaptic_transmissio | 0.92918612 |
| 83 | MP0002160_abnormal_reproductive_system | 0.92274462 |
| 84 | MP0002733_abnormal_thermal_nociception | 0.91449223 |
| 85 | MP0000955_abnormal_spinal_cord | 0.89701921 |
| 86 | MP0002572_abnormal_emotion/affect_behav | 0.87716391 |
| 87 | MP0003755_abnormal_palate_morphology | 0.86985869 |
| 88 | MP0002837_dystrophic_cardiac_calcinosis | 0.86864134 |
| 89 | MP0008775_abnormal_heart_ventricle | 0.78769676 |
| 90 | MP0000534_abnormal_ureter_morphology | 0.77096074 |
| 91 | MP0002116_abnormal_craniofacial_bone | 0.76920398 |
| 92 | MP0005085_abnormal_gallbladder_physiolo | 0.76381746 |
| 93 | MP0002063_abnormal_learning/memory/cond | 0.75459467 |
| 94 | MP0002138_abnormal_hepatobiliary_system | 0.75107197 |
| 95 | MP0002638_abnormal_pupillary_reflex | 0.71992311 |
| 96 | MP0001486_abnormal_startle_reflex | 0.70747588 |
| 97 | MP0001270_distended_abdomen | 0.70635283 |
| 98 | MP0002229_neurodegeneration | 0.69473202 |
| 99 | MP0000750_abnormal_muscle_regeneration | 0.68551321 |
| 100 | MP0000470_abnormal_stomach_morphology | 0.67856068 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Constricted visual fields (HP:0001133) | 6.31110771 |
| 2 | Abnormality of macular pigmentation (HP:0008002) | 6.01576121 |
| 3 | Reticulocytopenia (HP:0001896) | 5.15130639 |
| 4 | Metaphyseal cupping (HP:0003021) | 4.62437102 |
| 5 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 4.54343161 |
| 6 | Attenuation of retinal blood vessels (HP:0007843) | 4.40955811 |
| 7 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.24497197 |
| 8 | Cupped ribs (HP:0000887) | 4.15935655 |
| 9 | Striae distensae (HP:0001065) | 3.87167970 |
| 10 | Cone-rod dystrophy (HP:0000548) | 3.68002106 |
| 11 | Volvulus (HP:0002580) | 3.62741563 |
| 12 | Round ear (HP:0100830) | 3.51144658 |
| 13 | Macrocytic anemia (HP:0001972) | 3.51012698 |
| 14 | Abnormal number of erythroid precursors (HP:0012131) | 3.39074124 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 3.35761593 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.35761593 |
| 17 | Congenital sensorineural hearing impairment (HP:0008527) | 3.26917116 |
| 18 | Acute necrotizing encephalopathy (HP:0006965) | 3.16557756 |
| 19 | Acute encephalopathy (HP:0006846) | 3.08196487 |
| 20 | Toxemia of pregnancy (HP:0100603) | 3.08099253 |
| 21 | Hyperglycinemia (HP:0002154) | 3.00779303 |
| 22 | Abnormality of the labia minora (HP:0012880) | 2.98296941 |
| 23 | Optic disc pallor (HP:0000543) | 2.97159156 |
| 24 | Decreased muscle mass (HP:0003199) | 2.90803124 |
| 25 | Hyperthyroidism (HP:0000836) | 2.79443971 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.77111966 |
| 27 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.74115181 |
| 28 | Progressive macrocephaly (HP:0004481) | 2.61688378 |
| 29 | Septo-optic dysplasia (HP:0100842) | 2.57126280 |
| 30 | Small hand (HP:0200055) | 2.49223325 |
| 31 | Tibial bowing (HP:0002982) | 2.42259934 |
| 32 | Mitochondrial inheritance (HP:0001427) | 2.40224397 |
| 33 | Pallor (HP:0000980) | 2.35353010 |
| 34 | Pancreatic cysts (HP:0001737) | 2.32679317 |
| 35 | Severe visual impairment (HP:0001141) | 2.30598392 |
| 36 | Chronic hepatic failure (HP:0100626) | 2.29494287 |
| 37 | Pendular nystagmus (HP:0012043) | 2.28660187 |
| 38 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.22599804 |
| 39 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.20636474 |
| 40 | Cerebral edema (HP:0002181) | 2.18796143 |
| 41 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.15708606 |
| 42 | Congenital stationary night blindness (HP:0007642) | 2.12590637 |
| 43 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.10928974 |
| 44 | Nephronophthisis (HP:0000090) | 2.09158538 |
| 45 | Type 2 muscle fiber atrophy (HP:0003554) | 2.08572174 |
| 46 | Oligodontia (HP:0000677) | 2.08207551 |
| 47 | Large earlobe (HP:0009748) | 2.05367934 |
| 48 | Maternal diabetes (HP:0009800) | 2.05349974 |
| 49 | Asplenia (HP:0001746) | 2.02384556 |
| 50 | Increased CSF lactate (HP:0002490) | 2.01722417 |
| 51 | True hermaphroditism (HP:0010459) | 1.99912450 |
| 52 | Cystic liver disease (HP:0006706) | 1.98916025 |
| 53 | Prominent supraorbital ridges (HP:0000336) | 1.97075926 |
| 54 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.95770943 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 1.95770943 |
| 56 | Hyperalaninemia (HP:0003348) | 1.95770943 |
| 57 | Broad nasal tip (HP:0000455) | 1.94146635 |
| 58 | Thyroid-stimulating hormone excess (HP:0002925) | 1.93325422 |
| 59 | Femoral bowing (HP:0002980) | 1.92925501 |
| 60 | Ovoid vertebral bodies (HP:0003300) | 1.92868068 |
| 61 | Retinitis pigmentosa (HP:0000510) | 1.92250079 |
| 62 | Chorioretinal coloboma (HP:0000567) | 1.90952902 |
| 63 | Brushfield spots (HP:0001088) | 1.88961421 |
| 64 | Concave nail (HP:0001598) | 1.87024152 |
| 65 | Tetany (HP:0001281) | 1.86842431 |
| 66 | Supernumerary spleens (HP:0009799) | 1.82341026 |
| 67 | Absent septum pellucidum (HP:0001331) | 1.80488231 |
| 68 | Rib fusion (HP:0000902) | 1.80082469 |
| 69 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.78819414 |
| 70 | Abnormality of glycine metabolism (HP:0010895) | 1.78819414 |
| 71 | Muscle fiber atrophy (HP:0100295) | 1.78038332 |
| 72 | Postnatal growth retardation (HP:0008897) | 1.77829674 |
| 73 | Hypoplastic ilia (HP:0000946) | 1.77496302 |
| 74 | Poor suck (HP:0002033) | 1.76300610 |
| 75 | Hyperglycinuria (HP:0003108) | 1.74281131 |
| 76 | Chorioretinal atrophy (HP:0000533) | 1.73872816 |
| 77 | Partial duplication of thumb phalanx (HP:0009944) | 1.72237532 |
| 78 | Hyperphosphaturia (HP:0003109) | 1.71870490 |
| 79 | Absent thumb (HP:0009777) | 1.70577523 |
| 80 | Coxa vara (HP:0002812) | 1.70102331 |
| 81 | Anencephaly (HP:0002323) | 1.68711005 |
| 82 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.67011402 |
| 83 | Abnormality of the renal medulla (HP:0100957) | 1.66432465 |
| 84 | Adrenal hypoplasia (HP:0000835) | 1.66024950 |
| 85 | Lethargy (HP:0001254) | 1.64127511 |
| 86 | Stenosis of the external auditory canal (HP:0000402) | 1.63737625 |
| 87 | Abnormality of magnesium homeostasis (HP:0004921) | 1.63662089 |
| 88 | Optic nerve hypoplasia (HP:0000609) | 1.62318373 |
| 89 | Akinesia (HP:0002304) | 1.60920999 |
| 90 | Agitation (HP:0000713) | 1.60724607 |
| 91 | X-linked dominant inheritance (HP:0001423) | 1.60202984 |
| 92 | Sclerocornea (HP:0000647) | 1.59921466 |
| 93 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.58783949 |
| 94 | Optic nerve coloboma (HP:0000588) | 1.58012057 |
| 95 | Abnormality of serum amino acid levels (HP:0003112) | 1.56200770 |
| 96 | Confusion (HP:0001289) | 1.54421939 |
| 97 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.53773094 |
| 98 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.53773094 |
| 99 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.52670777 |
| 100 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.52670777 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KIT | 5.39302735 |
| 2 | CASK | 3.54304156 |
| 3 | CDK19 | 3.51251524 |
| 4 | BCKDK | 3.12500646 |
| 5 | DYRK2 | 2.81174306 |
| 6 | WNK4 | 2.68509191 |
| 7 | EPHB2 | 2.66652646 |
| 8 | EPHA4 | 2.24217265 |
| 9 | ADRBK2 | 2.22301938 |
| 10 | TEC | 2.21435569 |
| 11 | FRK | 2.19002167 |
| 12 | FES | 2.16423372 |
| 13 | TYRO3 | 1.99495685 |
| 14 | TIE1 | 1.96431077 |
| 15 | ZAK | 1.91899281 |
| 16 | GRK1 | 1.84179461 |
| 17 | ACVR1B | 1.80422182 |
| 18 | NTRK3 | 1.55638705 |
| 19 | PIK3CA | 1.51214603 |
| 20 | MARK1 | 1.39819968 |
| 21 | SIK2 | 1.32064556 |
| 22 | IKBKB | 1.31567410 |
| 23 | CAMK1D | 1.26626859 |
| 24 | NTRK2 | 1.22608783 |
| 25 | LRRK2 | 1.21957624 |
| 26 | BMPR1B | 1.19379058 |
| 27 | NUAK1 | 1.18608224 |
| 28 | PINK1 | 1.17751160 |
| 29 | RPS6KB2 | 1.11686800 |
| 30 | STK39 | 1.09272949 |
| 31 | ADRBK1 | 1.07509958 |
| 32 | TLK1 | 1.06198034 |
| 33 | MAP4K1 | 1.04957281 |
| 34 | ABL2 | 1.01233458 |
| 35 | MAP3K11 | 1.01077678 |
| 36 | VRK1 | 0.99525575 |
| 37 | OXSR1 | 0.94396358 |
| 38 | PRKCG | 0.93113429 |
| 39 | STK16 | 0.90029182 |
| 40 | PRKCI | 0.89608000 |
| 41 | PRKCQ | 0.87457991 |
| 42 | CAMKK2 | 0.87405034 |
| 43 | WNK3 | 0.83518538 |
| 44 | PAK3 | 0.82327178 |
| 45 | CAMK1G | 0.82033445 |
| 46 | BRAF | 0.78845127 |
| 47 | INSRR | 0.78069945 |
| 48 | DAPK2 | 0.76681648 |
| 49 | CAMK1 | 0.75737430 |
| 50 | SYK | 0.72940827 |
| 51 | DAPK3 | 0.72939429 |
| 52 | SGK223 | 0.71513085 |
| 53 | SGK494 | 0.71513085 |
| 54 | MAPK13 | 0.70363286 |
| 55 | PHKG1 | 0.70101968 |
| 56 | PHKG2 | 0.70101968 |
| 57 | PRKACA | 0.69471284 |
| 58 | AKT3 | 0.66345875 |
| 59 | FGR | 0.65113225 |
| 60 | IKBKE | 0.64691514 |
| 61 | PIM2 | 0.61835526 |
| 62 | PRKCA | 0.58875274 |
| 63 | PDK2 | 0.58560198 |
| 64 | MAP4K2 | 0.58116340 |
| 65 | TXK | 0.56258322 |
| 66 | CSNK1A1 | 0.54604451 |
| 67 | RPS6KA6 | 0.53543545 |
| 68 | CSK | 0.53244186 |
| 69 | CAMK2A | 0.51572729 |
| 70 | INSR | 0.51446628 |
| 71 | JAK3 | 0.51053664 |
| 72 | LIMK1 | 0.49832420 |
| 73 | SRC | 0.48769968 |
| 74 | VRK2 | 0.47884430 |
| 75 | PRKCZ | 0.47682753 |
| 76 | CSNK1G3 | 0.47441162 |
| 77 | KDR | 0.45683344 |
| 78 | PRKACG | 0.44756485 |
| 79 | CSNK1E | 0.44591182 |
| 80 | MUSK | 0.43935175 |
| 81 | PIM1 | 0.43345424 |
| 82 | NEK2 | 0.43308368 |
| 83 | PRKCD | 0.42316018 |
| 84 | HIPK2 | 0.42086453 |
| 85 | CCNB1 | 0.40353930 |
| 86 | TAOK3 | 0.39888965 |
| 87 | CSNK1A1L | 0.39593455 |
| 88 | RPS6KC1 | 0.39331656 |
| 89 | RPS6KL1 | 0.39331656 |
| 90 | RPS6KA5 | 0.39171484 |
| 91 | DYRK1B | 0.38580560 |
| 92 | CSNK1G2 | 0.38157673 |
| 93 | MINK1 | 0.37341898 |
| 94 | OBSCN | 0.37213744 |
| 95 | MATK | 0.35890633 |
| 96 | CDK11A | 0.35243204 |
| 97 | AURKA | 0.34045211 |
| 98 | TESK2 | 0.33435167 |
| 99 | CSF1R | 0.32411299 |
| 100 | PRKCE | 0.31725035 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.00381592 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.88465427 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 2.73807303 |
| 4 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.55325928 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.31323413 |
| 6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.21371460 |
| 7 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.14779886 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.14186253 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.13588464 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.09322233 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.04945704 |
| 12 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.01809558 |
| 13 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.98223062 |
| 14 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.90677312 |
| 15 | Phototransduction_Homo sapiens_hsa04744 | 1.86320825 |
| 16 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.85139025 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.73661665 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.68849801 |
| 19 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.60286406 |
| 20 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.57666392 |
| 21 | Nicotine addiction_Homo sapiens_hsa05033 | 1.56644546 |
| 22 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.47893220 |
| 23 | Histidine metabolism_Homo sapiens_hsa00340 | 1.44611034 |
| 24 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.41194646 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.39295527 |
| 26 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.38787455 |
| 27 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.35924747 |
| 28 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.33208170 |
| 29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.32292131 |
| 30 | Retinol metabolism_Homo sapiens_hsa00830 | 1.30269789 |
| 31 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.28715384 |
| 32 | RNA polymerase_Homo sapiens_hsa03020 | 1.26257630 |
| 33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.20734128 |
| 34 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.19778281 |
| 35 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.19100131 |
| 36 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.16005231 |
| 37 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.09020477 |
| 38 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.07529472 |
| 39 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.00249001 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.98586914 |
| 41 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.98572112 |
| 42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.95285152 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.94860831 |
| 44 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.94533278 |
| 45 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.92504114 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.91175493 |
| 47 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.88536738 |
| 48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.88265638 |
| 49 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.84941464 |
| 50 | Metabolic pathways_Homo sapiens_hsa01100 | 0.82964428 |
| 51 | RNA degradation_Homo sapiens_hsa03018 | 0.81750647 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.80077001 |
| 53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79435475 |
| 54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.78366513 |
| 55 | Morphine addiction_Homo sapiens_hsa05032 | 0.77955442 |
| 56 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.77820011 |
| 57 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.77635868 |
| 58 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.74186767 |
| 59 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.69939610 |
| 60 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.66556398 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.66302879 |
| 62 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.66025253 |
| 63 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.65757592 |
| 64 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.64660169 |
| 65 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.62662670 |
| 66 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.59788380 |
| 67 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.59633409 |
| 68 | Mineral absorption_Homo sapiens_hsa04978 | 0.59097226 |
| 69 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.58273354 |
| 70 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.57067898 |
| 71 | Taste transduction_Homo sapiens_hsa04742 | 0.56955233 |
| 72 | Purine metabolism_Homo sapiens_hsa00230 | 0.56435177 |
| 73 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55150802 |
| 74 | Protein export_Homo sapiens_hsa03060 | 0.52546955 |
| 75 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.52074551 |
| 76 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.52003929 |
| 77 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.51658191 |
| 78 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.50556757 |
| 79 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.47534505 |
| 80 | Insulin secretion_Homo sapiens_hsa04911 | 0.47423072 |
| 81 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.46464238 |
| 82 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.44740044 |
| 83 | GABAergic synapse_Homo sapiens_hsa04727 | 0.44185824 |
| 84 | Galactose metabolism_Homo sapiens_hsa00052 | 0.43397090 |
| 85 | Allograft rejection_Homo sapiens_hsa05330 | 0.41665759 |
| 86 | Alcoholism_Homo sapiens_hsa05034 | 0.41505928 |
| 87 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.39927626 |
| 88 | Bile secretion_Homo sapiens_hsa04976 | 0.39629364 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39571995 |
| 90 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.39477818 |
| 91 | Basal transcription factors_Homo sapiens_hsa03022 | 0.38019799 |
| 92 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.37265192 |
| 93 | Circadian entrainment_Homo sapiens_hsa04713 | 0.35319990 |
| 94 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.35236730 |
| 95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.35071960 |
| 96 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.34784957 |
| 97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.34779958 |
| 98 | Proteasome_Homo sapiens_hsa03050 | 0.33398932 |
| 99 | Homologous recombination_Homo sapiens_hsa03440 | 0.31849189 |
| 100 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31816823 |

