RPS2P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)8.89759866
2viral transcription (GO:0019083)8.40965711
3translational termination (GO:0006415)8.08143196
4ribosomal small subunit biogenesis (GO:0042274)7.14354117
5translational elongation (GO:0006414)6.81327542
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.75178792
7cotranslational protein targeting to membrane (GO:0006613)6.61829817
8maturation of SSU-rRNA (GO:0030490)6.59341147
9protein targeting to ER (GO:0045047)6.58439369
10establishment of protein localization to endoplasmic reticulum (GO:0072599)6.26903536
11protein localization to endoplasmic reticulum (GO:0070972)6.20079819
12cellular protein complex disassembly (GO:0043624)6.17014107
13viral life cycle (GO:0019058)6.08600894
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)6.02660821
15ATP synthesis coupled proton transport (GO:0015986)5.45105031
16energy coupled proton transport, down electrochemical gradient (GO:0015985)5.45105031
17translational initiation (GO:0006413)5.32161721
18mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.28745525
19protein complex disassembly (GO:0043241)5.24985544
20ribosomal large subunit biogenesis (GO:0042273)4.93431911
21macromolecular complex disassembly (GO:0032984)4.91689128
22DNA deamination (GO:0045006)4.88052259
23chaperone-mediated protein transport (GO:0072321)4.40264188
24translation (GO:0006412)4.36306672
25GTP biosynthetic process (GO:0006183)4.35595843
26nuclear-transcribed mRNA catabolic process (GO:0000956)4.34325019
27protein targeting to membrane (GO:0006612)4.31702238
28protein complex biogenesis (GO:0070271)4.19175144
29mRNA catabolic process (GO:0006402)4.09971465
30epithelial cell maturation (GO:0002070)4.05602614
31mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.05383225
32pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.03687718
33mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.02772877
34mitochondrial respiratory chain complex I assembly (GO:0032981)4.02772877
35NADH dehydrogenase complex assembly (GO:0010257)4.02772877
36respiratory electron transport chain (GO:0022904)4.01799317
37electron transport chain (GO:0022900)3.99573679
38base-excision repair, AP site formation (GO:0006285)3.93742849
39establishment of protein localization to mitochondrial membrane (GO:0090151)3.93356385
40UTP biosynthetic process (GO:0006228)3.91755630
41ribonucleoprotein complex biogenesis (GO:0022613)3.86071664
42RNA catabolic process (GO:0006401)3.81873340
43mitochondrial respiratory chain complex assembly (GO:0033108)3.71672446
44cellular component biogenesis (GO:0044085)3.70213398
45UTP metabolic process (GO:0046051)3.70035860
46RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.56651763
47tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.56651763
48pseudouridine synthesis (GO:0001522)3.47359676
49purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.42417332
50purine nucleoside triphosphate biosynthetic process (GO:0009145)3.37046965
51rRNA processing (GO:0006364)3.35166862
52deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.32462245
53protein neddylation (GO:0045116)3.30069205
54rRNA metabolic process (GO:0016072)3.27473556
55guanosine-containing compound biosynthetic process (GO:1901070)3.23996584
56nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.22995723
57pyrimidine nucleotide catabolic process (GO:0006244)3.21808655
58pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.18211760
59exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.18017405
60transcription elongation from RNA polymerase III promoter (GO:0006385)3.17417336
61termination of RNA polymerase III transcription (GO:0006386)3.17417336
62deoxyribonucleotide catabolic process (GO:0009264)3.16267992
63CTP biosynthetic process (GO:0006241)3.15512394
64CTP metabolic process (GO:0046036)3.15512394
65deoxyribose phosphate catabolic process (GO:0046386)3.14841881
66ATP biosynthetic process (GO:0006754)3.12992539
67ncRNA 3-end processing (GO:0043628)3.10162948
68pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.09930807
69ribonucleoside triphosphate biosynthetic process (GO:0009201)3.05769648
70pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.99897660
71regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.99221374
72respiratory chain complex IV assembly (GO:0008535)2.92957774
73pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.90521321
74behavioral response to nicotine (GO:0035095)2.87449082
75establishment of protein localization to membrane (GO:0090150)2.87070255
76cytochrome complex assembly (GO:0017004)2.85704047
77hydrogen ion transmembrane transport (GO:1902600)2.82891528
78purine deoxyribonucleotide catabolic process (GO:0009155)2.81324257
79rRNA modification (GO:0000154)2.80837186
80pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.79845401
81protein targeting (GO:0006605)2.77990124
82GPI anchor biosynthetic process (GO:0006506)2.75675525
83sequestering of actin monomers (GO:0042989)2.72152178
84preassembly of GPI anchor in ER membrane (GO:0016254)2.71482667
85neuron fate specification (GO:0048665)2.68543257
86nucleoside triphosphate biosynthetic process (GO:0009142)2.66673559
87establishment of protein localization to organelle (GO:0072594)2.66239837
88chromatin remodeling at centromere (GO:0031055)2.63178567
89tRNA processing (GO:0008033)2.62853106
90epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.61707574
91regulation of cell-cell adhesion mediated by cadherin (GO:2000047)2.61429714
92regulation of mitochondrial translation (GO:0070129)2.60763269
93cytidine deamination (GO:0009972)2.60652942
94cytidine metabolic process (GO:0046087)2.60652942
95cytidine catabolic process (GO:0006216)2.60652942
96water-soluble vitamin biosynthetic process (GO:0042364)2.60092146
97protein targeting to mitochondrion (GO:0006626)2.59649248
98positive regulation of megakaryocyte differentiation (GO:0045654)2.59111071
99GPI anchor metabolic process (GO:0006505)2.58906488
100purine nucleotide salvage (GO:0032261)2.58354219

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.91536366
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.97033669
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.72720143
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.70256853
5TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.56906241
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.55899332
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.28673600
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.15001799
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.01320703
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.87044139
11HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.69072900
12TP63_19390658_ChIP-ChIP_HaCaT_Human2.65292270
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.59851229
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.58456023
15XRN2_22483619_ChIP-Seq_HELA_Human2.38322618
16NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.38225898
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.36441879
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.32972623
19ESR1_15608294_ChIP-ChIP_MCF-7_Human2.26261027
20CEBPB_24764292_ChIP-Seq_MC3T3_Mouse2.25071809
21CREB1_15753290_ChIP-ChIP_HEK293T_Human2.24193325
22VDR_23849224_ChIP-Seq_CD4+_Human2.21388576
23FOXP3_21729870_ChIP-Seq_TREG_Human2.15953558
24NOTCH1_21737748_ChIP-Seq_TLL_Human2.14286887
25TTF2_22483619_ChIP-Seq_HELA_Human2.11143305
26EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.10540736
27MYC_19079543_ChIP-ChIP_MESCs_Mouse2.10194483
28CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.91395195
29MYC_19030024_ChIP-ChIP_MESCs_Mouse1.81638013
30MYC_18940864_ChIP-ChIP_HL60_Human1.79483986
31PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.67990716
32POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.67170030
33BMI1_23680149_ChIP-Seq_NPCS_Mouse1.64892837
34TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.59977851
35SRF_21415370_ChIP-Seq_HL-1_Mouse1.58586490
36DCP1A_22483619_ChIP-Seq_HELA_Human1.57275356
37ZNF263_19887448_ChIP-Seq_K562_Human1.56012438
38VDR_22108803_ChIP-Seq_LS180_Human1.55986156
39E2F1_18555785_ChIP-Seq_MESCs_Mouse1.51449444
40GABP_19822575_ChIP-Seq_HepG2_Human1.50492052
41TP53_20018659_ChIP-ChIP_R1E_Mouse1.48312764
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.46263702
43FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.45497786
44CBX2_27304074_Chip-Seq_ESCs_Mouse1.44563244
45EZH2_22144423_ChIP-Seq_EOC_Human1.39968820
46CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.38242933
47FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.37628390
48FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.36272297
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.35226510
50KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.34176280
51RNF2_27304074_Chip-Seq_NSC_Mouse1.33769514
52E2F4_17652178_ChIP-ChIP_JURKAT_Human1.31939204
53EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.31192327
54SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.26668227
55CTCF_18555785_ChIP-Seq_MESCs_Mouse1.24460573
56CIITA_25753668_ChIP-Seq_RAJI_Human1.23286214
57RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.22956510
58KDM5A_27292631_Chip-Seq_BREAST_Human1.19825972
59YY1_22570637_ChIP-Seq_MALME-3M_Human1.19677683
60TP53_22573176_ChIP-Seq_HFKS_Human1.19626491
61ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.17027724
62CTCF_26484167_Chip-Seq_Bcells_Mouse1.16400066
63ZNF274_21170338_ChIP-Seq_K562_Hela1.16164197
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.14038493
65EWS_26573619_Chip-Seq_HEK293_Human1.12940385
66BP1_19119308_ChIP-ChIP_Hs578T_Human1.12563970
67HOXB4_20404135_ChIP-ChIP_EML_Mouse1.10682269
68EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.10660349
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.10146866
70BCL6_27268052_Chip-Seq_Bcells_Human1.09908420
71EZH2_27304074_Chip-Seq_ESCs_Mouse1.08407928
72NANOG_20526341_ChIP-Seq_ESCs_Human1.07509788
73TAF2_19829295_ChIP-Seq_ESCs_Human1.07105563
74SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.05561244
75ELK1_19687146_ChIP-ChIP_HELA_Human1.04520133
76TET1_21451524_ChIP-Seq_MESCs_Mouse1.01719736
77SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.01235641
78SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.00327764
79MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.00296529
80JARID2_20064375_ChIP-Seq_MESCs_Mouse0.99360553
81FOXP1_21924763_ChIP-Seq_HESCs_Human0.98237261
82VDR_21846776_ChIP-Seq_THP-1_Human0.98225162
83ERA_21632823_ChIP-Seq_H3396_Human0.97863825
84CTCF_20526341_ChIP-Seq_ESCs_Human0.97052902
85BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.96797140
86E2F1_20622854_ChIP-Seq_HELA_Human0.96175771
87HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.95388479
88IRF1_19129219_ChIP-ChIP_H3396_Human0.95377291
89PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.94362088
90LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.92746729
91SOX2_18555785_ChIP-Seq_MESCs_Mouse0.91861419
92SA1_27219007_Chip-Seq_Bcells_Human0.90216185
93STAT1_20625510_ChIP-Seq_HELA_Human0.89337900
94P68_20966046_ChIP-Seq_HELA_Human0.86822769
95RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86796295
96JARID2_20075857_ChIP-Seq_MESCs_Mouse0.84099022
97E2F1_21310950_ChIP-Seq_MCF-7_Human0.81790914
98TDRD3_21172665_ChIP-Seq_MCF-7_Human0.81274529
99P53_21459846_ChIP-Seq_SAOS-2_Human0.81004711
100FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.80887693

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.50783140
2MP0006292_abnormal_olfactory_placode4.81182670
3MP0005646_abnormal_pituitary_gland3.60730344
4MP0005377_hearing/vestibular/ear_phenot2.77775251
5MP0003878_abnormal_ear_physiology2.77775251
6MP0002160_abnormal_reproductive_system2.01902552
7MP0005075_abnormal_melanosome_morpholog1.99662510
8MP0002234_abnormal_pharynx_morphology1.93034898
9MP0002837_dystrophic_cardiac_calcinosis1.88323487
10MP0000566_synostosis1.82080512
11MP0008995_early_reproductive_senescence1.77554209
12MP0005671_abnormal_response_to1.76213488
13MP0002163_abnormal_gland_morphology1.75341093
14MP0000049_abnormal_middle_ear1.74569389
15MP0000579_abnormal_nail_morphology1.72621768
16MP0004142_abnormal_muscle_tone1.70379736
17MP0008872_abnormal_physiological_respon1.67632030
18MP0003787_abnormal_imprinting1.64672494
19MP0001293_anophthalmia1.64280988
20MP0008875_abnormal_xenobiotic_pharmacok1.61206974
21MP0003123_paternal_imprinting1.55001723
22MP0004147_increased_porphyrin_level1.47419806
23MP0005389_reproductive_system_phenotype1.46896214
24MP0008789_abnormal_olfactory_epithelium1.45211876
25MP0002736_abnormal_nociception_after1.44754331
26MP0004133_heterotaxia1.42165248
27MP0001919_abnormal_reproductive_system1.38788663
28MP0000631_abnormal_neuroendocrine_gland1.33768699
29MP0001346_abnormal_lacrimal_gland1.32490121
30MP0008058_abnormal_DNA_repair1.32131283
31MP0005645_abnormal_hypothalamus_physiol1.31525385
32MP0001968_abnormal_touch/_nociception1.30188291
33MP0004885_abnormal_endolymph1.28965581
34MP0002876_abnormal_thyroid_physiology1.26780710
35MP0002909_abnormal_adrenal_gland1.24493768
36MP0002938_white_spotting1.22199482
37MP0003567_abnormal_fetal_cardiomyocyte1.21104075
38MP0002098_abnormal_vibrissa_morphology1.19572057
39MP0003186_abnormal_redox_activity1.18759376
40MP0001764_abnormal_homeostasis1.18203259
41MP0000681_abnormal_thyroid_gland1.18183224
42MP0003693_abnormal_embryo_hatching1.17371037
43MP0001905_abnormal_dopamine_level1.16427645
44MP0009278_abnormal_bone_marrow1.16195898
45MP0001529_abnormal_vocalization1.14974798
46MP0000678_abnormal_parathyroid_gland1.14648435
47MP0008877_abnormal_DNA_methylation1.14161932
48MP0010030_abnormal_orbit_morphology1.14006312
49MP0002249_abnormal_larynx_morphology1.13799346
50MP0005220_abnormal_exocrine_pancreas1.13695295
51MP0002095_abnormal_skin_pigmentation1.13523499
52MP0005551_abnormal_eye_electrophysiolog1.10033377
53MP0009053_abnormal_anal_canal1.09007064
54MP0003646_muscle_fatigue1.08722054
55MP0001485_abnormal_pinna_reflex1.08327697
56MP0003936_abnormal_reproductive_system1.07312231
57MP0003786_premature_aging1.02785011
58MP0009333_abnormal_splenocyte_physiolog1.02099843
59MP0000516_abnormal_urinary_system1.01471580
60MP0005367_renal/urinary_system_phenotyp1.01471580
61MP0005084_abnormal_gallbladder_morpholo0.99362910
62MP0000372_irregular_coat_pigmentation0.96068471
63MP0002210_abnormal_sex_determination0.95501779
64MP0005670_abnormal_white_adipose0.93650841
65MP0006072_abnormal_retinal_apoptosis0.92940903
66MP0002138_abnormal_hepatobiliary_system0.87033916
67MP0001986_abnormal_taste_sensitivity0.86819580
68MP0003942_abnormal_urinary_system0.86723124
69MP0000026_abnormal_inner_ear0.85159501
70MP0002102_abnormal_ear_morphology0.83750052
71MP0005499_abnormal_olfactory_system0.83536578
72MP0005394_taste/olfaction_phenotype0.83536578
73MP0001324_abnormal_eye_pigmentation0.82620268
74MP0002693_abnormal_pancreas_physiology0.82405051
75MP0001145_abnormal_male_reproductive0.82014972
76MP0001835_abnormal_antigen_presentation0.81537288
77MP0004145_abnormal_muscle_electrophysio0.81013862
78MP0001963_abnormal_hearing_physiology0.80080965
79MP0000653_abnormal_sex_gland0.78105672
80MP0000015_abnormal_ear_pigmentation0.77617185
81MP0003866_abnormal_defecation0.76687724
82MP0005410_abnormal_fertilization0.76171506
83MP0001944_abnormal_pancreas_morphology0.75275909
84MP0002277_abnormal_respiratory_mucosa0.74559465
85MP0001119_abnormal_female_reproductive0.74521234
86MP0002638_abnormal_pupillary_reflex0.73745200
87MP0005174_abnormal_tail_pigmentation0.73667882
88MP0002148_abnormal_hypersensitivity_rea0.73549738
89MP0002653_abnormal_ependyma_morphology0.72035433
90MP0005636_abnormal_mineral_homeostasis0.71797158
91MP0001881_abnormal_mammary_gland0.71556158
92MP0005195_abnormal_posterior_eye0.71548830
93MP0001800_abnormal_humoral_immune0.70793194
94MP0000627_abnormal_mammary_gland0.69717374
95MP0009785_altered_susceptibility_to0.68894900
96MP0003638_abnormal_response/metabolism_0.68393627
97MP0009250_abnormal_appendicular_skeleto0.68367570
98MP0006276_abnormal_autonomic_nervous0.67658382
99MP0002398_abnormal_bone_marrow0.67610987
100MP0003283_abnormal_digestive_organ0.66372394

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)5.30824516
2Concave nail (HP:0001598)5.27369489
3Abnormality of cells of the erythroid lineage (HP:0012130)4.52403455
4Acute necrotizing encephalopathy (HP:0006965)4.26891766
5Mitochondrial inheritance (HP:0001427)4.10979550
6Abnormal number of erythroid precursors (HP:0012131)3.98408305
7Abnormal mitochondria in muscle tissue (HP:0008316)3.87394019
8Macrocytic anemia (HP:0001972)3.80331770
9Acute encephalopathy (HP:0006846)3.59672469
10Aplasia/Hypoplasia of the sacrum (HP:0008517)3.51540907
11Increased CSF lactate (HP:0002490)3.47551171
12Pallor (HP:0000980)3.46583114
13Absent rod-and cone-mediated responses on ERG (HP:0007688)3.46228506
14Hepatocellular necrosis (HP:0001404)3.46170631
15Progressive macrocephaly (HP:0004481)3.38253427
16Increased hepatocellular lipid droplets (HP:0006565)3.35030181
17Abnormality of lateral ventricle (HP:0030047)3.26081554
18Lipid accumulation in hepatocytes (HP:0006561)3.15883680
19Renal Fanconi syndrome (HP:0001994)3.13873174
20Aplastic anemia (HP:0001915)3.09101594
21Hepatic necrosis (HP:0002605)3.08580069
223-Methylglutaconic aciduria (HP:0003535)3.07542791
23Absent thumb (HP:0009777)2.87854416
24Pancreatic cysts (HP:0001737)2.83013535
25Increased intramyocellular lipid droplets (HP:0012240)2.81038331
26Pancreatic fibrosis (HP:0100732)2.77246676
27Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.73260792
28Decreased activity of mitochondrial respiratory chain (HP:0008972)2.73260792
29Abnormal rod and cone electroretinograms (HP:0008323)2.71644361
30Cerebral edema (HP:0002181)2.70498528
31Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.67702225
32True hermaphroditism (HP:0010459)2.65800756
33Triphalangeal thumb (HP:0001199)2.59815052
34Abnormality of the parietal bone (HP:0002696)2.55027450
35Abnormality of midbrain morphology (HP:0002418)2.53503095
36Molar tooth sign on MRI (HP:0002419)2.53503095
37Congenital stationary night blindness (HP:0007642)2.49373897
38Exertional dyspnea (HP:0002875)2.44021652
39Optic disc pallor (HP:0000543)2.41151366
40Increased muscle lipid content (HP:0009058)2.40991254
41Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.33243165
42Abnormality of the phalanges of the 5th finger (HP:0004213)2.30809867
43Constricted visual fields (HP:0001133)2.25637293
44Lactic acidosis (HP:0003128)2.23430086
45Abnormality of DNA repair (HP:0003254)2.21849570
46Pendular nystagmus (HP:0012043)2.21755190
47Increased serum lactate (HP:0002151)2.19673473
48Abnormality of the phalanges of the 2nd finger (HP:0009541)2.13385690
49Hyperglycinemia (HP:0002154)2.13040694
50Microretrognathia (HP:0000308)2.11040995
51Thrombocytosis (HP:0001894)2.10042136
52Elevated erythrocyte sedimentation rate (HP:0003565)2.09567776
53Sclerocornea (HP:0000647)2.07369108
54Hypoplasia of the radius (HP:0002984)2.06926752
55Optic nerve hypoplasia (HP:0000609)2.06692752
56Panhypogammaglobulinemia (HP:0003139)2.05481892
57Respiratory difficulties (HP:0002880)2.04779017
58Abnormal respiratory epithelium morphology (HP:0012253)2.02839878
59Abnormal respiratory motile cilium morphology (HP:0005938)2.02839878
60Pancytopenia (HP:0001876)2.02535934
61Muscle fiber atrophy (HP:0100295)2.01861744
62Abolished electroretinogram (ERG) (HP:0000550)2.01692963
63Anencephaly (HP:0002323)2.01473668
64Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.01386455
65Abnormal respiratory motile cilium physiology (HP:0012261)2.00001672
66Asplenia (HP:0001746)1.98994199
67Cystic liver disease (HP:0006706)1.98697809
68Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.98404382
69Aplasia/Hypoplasia of the spleen (HP:0010451)1.95087261
70Respiratory failure (HP:0002878)1.93723575
71Decreased electroretinogram (ERG) amplitude (HP:0000654)1.93521247
72Lethargy (HP:0001254)1.92478388
73Abnormality of renal resorption (HP:0011038)1.92089849
74Septate vagina (HP:0001153)1.90233450
75Aplasia/Hypoplasia of the uvula (HP:0010293)1.90090662
76Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.89740663
77Chromosomal breakage induced by crosslinking agents (HP:0003221)1.89025769
78Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.88882814
79Attenuation of retinal blood vessels (HP:0007843)1.87637746
80Symphalangism affecting the phalanges of the hand (HP:0009773)1.87181315
81Type 2 muscle fiber atrophy (HP:0003554)1.86943288
82Exercise intolerance (HP:0003546)1.83775642
83Cleft eyelid (HP:0000625)1.82450132
84Abnormality of the renal collecting system (HP:0004742)1.82208604
85Bile duct proliferation (HP:0001408)1.81103047
86Abnormal biliary tract physiology (HP:0012439)1.81103047
87Short middle phalanx of the 5th finger (HP:0004220)1.80121480
88Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.78434561
89Renal dysplasia (HP:0000110)1.76479065
90Hyperphosphaturia (HP:0003109)1.76205866
91Chromsome breakage (HP:0040012)1.75593381
92Decreased central vision (HP:0007663)1.73589313
93Colon cancer (HP:0003003)1.73090714
94Stenosis of the external auditory canal (HP:0000402)1.72594741
95Agammaglobulinemia (HP:0004432)1.72005886
96Abnormal hemoglobin (HP:0011902)1.71294720
97Meckel diverticulum (HP:0002245)1.71227711
98Abnormality of the 2nd finger (HP:0004100)1.70188577
99Short thumb (HP:0009778)1.69622198
100Abnormality of the ileum (HP:0001549)1.69614421

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.18896359
2BCKDK3.39717868
3KDR2.83956221
4PIM22.81357502
5NME22.53983787
6CDK192.44939679
7TLK12.39764764
8STK162.36481618
9VRK12.13763747
10TXK2.12534592
11PASK2.09283566
12ADRBK21.97699732
13TESK21.93523996
14ZAK1.87133577
15RPS6KB21.79487134
16GRK11.73207274
17NUAK11.72425292
18MUSK1.70477069
19TAOK31.69569312
20DYRK21.57754563
21PIK3CA1.53112468
22TAF11.51021665
23EPHA21.46178560
24BUB11.45542514
25MAP4K11.43675600
26WNK41.32075587
27CDC71.28018137
28MAP3K111.20156501
29MAP4K21.14954351
30KIT1.13673506
31LRRK21.11999419
32SCYL21.09655004
33PIM11.09621113
34GRK61.08696455
35CCNB11.06091713
36RPS6KA61.05411491
37IKBKB1.04540658
38TIE11.02721635
39AURKA1.00992038
40RPS6KC11.00727237
41RPS6KL11.00727237
42PINK10.96290288
43TRIM280.94512532
44NME10.94043428
45ITK0.91124754
46BMPR1B0.90476759
47TEC0.89851814
48TNK20.88945673
49ABL20.88380987
50ADRBK10.87259560
51DAPK30.82037156
52PRKCQ0.81349154
53ILK0.79524151
54MAP2K70.77666146
55CSF1R0.74851178
56STK40.74809158
57PLK40.73953009
58AURKB0.73837019
59SIK10.73188095
60CHEK20.71559234
61ATR0.70757111
62IKBKE0.69614887
63SYK0.68100509
64NEK10.67321239
65UHMK10.66615914
66CSNK2A20.66179539
67CDK70.65057232
68NEK20.63095696
69INSRR0.62502186
70CSNK2A10.62376010
71DAPK10.59943854
72CDK80.58985545
73LYN0.58854258
74RPS6KA50.56938629
75OXSR10.56654442
76PLK10.55882664
77MAP3K120.53702663
78HIPK20.52676912
79PRKCD0.51956927
80DYRK1B0.51212978
81TGFBR10.49864289
82FES0.49019218
83LIMK10.48930157
84CHUK0.48836115
85BTK0.47459551
86MAP2K20.45878438
87MKNK10.43908255
88EIF2AK10.43810597
89CSNK1A10.43662922
90BMPR20.43189554
91WNK30.42948690
92MAPK150.41749731
93RPS6KB10.41724320
94PRKCI0.40726778
95RPS6KA10.39509671
96PRKCG0.39076465
97MAPKAPK30.38663035
98PRKACA0.38063263
99PRKCA0.36966898
100LCK0.35567815

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.99917365
2Oxidative phosphorylation_Homo sapiens_hsa001904.28940767
3Parkinsons disease_Homo sapiens_hsa050123.44819295
4Proteasome_Homo sapiens_hsa030503.09382999
5RNA polymerase_Homo sapiens_hsa030202.75806376
6Huntingtons disease_Homo sapiens_hsa050162.44597471
7Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.37544680
8Alzheimers disease_Homo sapiens_hsa050102.22952756
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.22560681
10Base excision repair_Homo sapiens_hsa034102.13639204
11Primary immunodeficiency_Homo sapiens_hsa053402.13634528
12DNA replication_Homo sapiens_hsa030301.99085582
13Asthma_Homo sapiens_hsa053101.99040315
14Cardiac muscle contraction_Homo sapiens_hsa042601.97963831
15One carbon pool by folate_Homo sapiens_hsa006701.93258466
16Homologous recombination_Homo sapiens_hsa034401.88677893
17Pyrimidine metabolism_Homo sapiens_hsa002401.83738590
18Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.67892881
19Allograft rejection_Homo sapiens_hsa053301.67316951
20Fanconi anemia pathway_Homo sapiens_hsa034601.59921683
21Intestinal immune network for IgA production_Homo sapiens_hsa046721.59518199
22Graft-versus-host disease_Homo sapiens_hsa053321.58713156
23Spliceosome_Homo sapiens_hsa030401.57217527
24Sulfur relay system_Homo sapiens_hsa041221.54944039
25RNA degradation_Homo sapiens_hsa030181.50257231
26Autoimmune thyroid disease_Homo sapiens_hsa053201.50234019
27Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.44619473
28Type I diabetes mellitus_Homo sapiens_hsa049401.39638225
29Nucleotide excision repair_Homo sapiens_hsa034201.25513671
30Phototransduction_Homo sapiens_hsa047441.21334069
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.18420102
32Mismatch repair_Homo sapiens_hsa034301.15982217
33Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.12115176
34Protein export_Homo sapiens_hsa030601.12077714
35Purine metabolism_Homo sapiens_hsa002301.10093307
36Antigen processing and presentation_Homo sapiens_hsa046121.09147061
37Selenocompound metabolism_Homo sapiens_hsa004501.04819380
38Peroxisome_Homo sapiens_hsa041461.00088416
39Linoleic acid metabolism_Homo sapiens_hsa005910.99931258
40Maturity onset diabetes of the young_Homo sapiens_hsa049500.95041201
41RNA transport_Homo sapiens_hsa030130.93784101
42Basal transcription factors_Homo sapiens_hsa030220.93090381
43Tryptophan metabolism_Homo sapiens_hsa003800.89089783
44Nitrogen metabolism_Homo sapiens_hsa009100.86525549
45Butanoate metabolism_Homo sapiens_hsa006500.83484717
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.80152154
47Cysteine and methionine metabolism_Homo sapiens_hsa002700.77324401
48Steroid hormone biosynthesis_Homo sapiens_hsa001400.76486345
49Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.74715362
50Systemic lupus erythematosus_Homo sapiens_hsa053220.74333092
51Rheumatoid arthritis_Homo sapiens_hsa053230.74235186
52Metabolic pathways_Homo sapiens_hsa011000.71052195
53Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.70649860
54alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.67454172
55Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.65357170
56Collecting duct acid secretion_Homo sapiens_hsa049660.64644760
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.64260480
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61124942
59Chemical carcinogenesis_Homo sapiens_hsa052040.59529995
60Arachidonic acid metabolism_Homo sapiens_hsa005900.58711671
61Hematopoietic cell lineage_Homo sapiens_hsa046400.58298358
62Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.57930571
63Caffeine metabolism_Homo sapiens_hsa002320.57504859
64Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.54591836
65Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.53213371
66Olfactory transduction_Homo sapiens_hsa047400.50143835
67Fatty acid elongation_Homo sapiens_hsa000620.48784551
68Sulfur metabolism_Homo sapiens_hsa009200.46733163
69p53 signaling pathway_Homo sapiens_hsa041150.46457666
70Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.44990560
71Folate biosynthesis_Homo sapiens_hsa007900.44601627
72Retinol metabolism_Homo sapiens_hsa008300.42871560
73Propanoate metabolism_Homo sapiens_hsa006400.42815819
74Glutathione metabolism_Homo sapiens_hsa004800.41590437
75Tyrosine metabolism_Homo sapiens_hsa003500.38950474
76Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.38416605
77Fat digestion and absorption_Homo sapiens_hsa049750.37197088
78Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36353581
79Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.36227928
80Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.33245934
81Ovarian steroidogenesis_Homo sapiens_hsa049130.33040398
82Epstein-Barr virus infection_Homo sapiens_hsa051690.32927253
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.31399926
84Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.30553955
85Taste transduction_Homo sapiens_hsa047420.30241388
86Ether lipid metabolism_Homo sapiens_hsa005650.30188375
87Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.27897237
88Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.23502658
89Regulation of autophagy_Homo sapiens_hsa041400.22586576
90Arginine and proline metabolism_Homo sapiens_hsa003300.20544403
91HTLV-I infection_Homo sapiens_hsa051660.19738421
92Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18985338
93Viral myocarditis_Homo sapiens_hsa054160.18135630
94Pyruvate metabolism_Homo sapiens_hsa006200.16817347
95Pentose and glucuronate interconversions_Homo sapiens_hsa000400.16181385
96beta-Alanine metabolism_Homo sapiens_hsa004100.15791420
97Nicotine addiction_Homo sapiens_hsa050330.13428833
98Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.13325338
99Herpes simplex infection_Homo sapiens_hsa051680.12032292
100Primary bile acid biosynthesis_Homo sapiens_hsa001200.10885935

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »