RPS3AP26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.73262080
2ribosomal small subunit assembly (GO:0000028)5.59601025
3cytidine deamination (GO:0009972)4.32344324
4cytidine metabolic process (GO:0046087)4.32344324
5cytidine catabolic process (GO:0006216)4.32344324
6regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.16224343
7RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.08158781
8tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.08158781
9viral transcription (GO:0019083)3.67680169
10pyrimidine ribonucleoside catabolic process (GO:0046133)3.66333807
11translational termination (GO:0006415)3.59786098
12ribosomal large subunit biogenesis (GO:0042273)3.52956414
13energy coupled proton transport, down electrochemical gradient (GO:0015985)3.51341283
14ATP synthesis coupled proton transport (GO:0015986)3.51341283
15protein neddylation (GO:0045116)3.42499318
16mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.41883187
17translational elongation (GO:0006414)3.35044487
18regulation of memory T cell differentiation (GO:0043380)3.29746333
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.28666006
20iron-sulfur cluster assembly (GO:0016226)3.22155710
21metallo-sulfur cluster assembly (GO:0031163)3.22155710
22protein complex biogenesis (GO:0070271)3.22022911
23cotranslational protein targeting to membrane (GO:0006613)3.21215074
24nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.20671397
25exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.18092051
26protein targeting to ER (GO:0045047)3.17484407
27mitochondrial respiratory chain complex I assembly (GO:0032981)3.16752995
28NADH dehydrogenase complex assembly (GO:0010257)3.16752995
29mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.16752995
30negative regulation of mast cell activation (GO:0033004)3.14890235
31piRNA metabolic process (GO:0034587)3.10028896
32protein localization to endoplasmic reticulum (GO:0070972)3.03567613
33establishment of protein localization to endoplasmic reticulum (GO:0072599)3.02335191
34kynurenine metabolic process (GO:0070189)3.01903814
35tryptophan catabolic process (GO:0006569)3.01658995
36indole-containing compound catabolic process (GO:0042436)3.01658995
37indolalkylamine catabolic process (GO:0046218)3.01658995
38positive regulation of defense response to virus by host (GO:0002230)2.99721510
39mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.99150982
40pseudouridine synthesis (GO:0001522)2.98929965
41behavioral response to nicotine (GO:0035095)2.98553529
42regulation of regulatory T cell differentiation (GO:0045589)2.96357808
43mitochondrial respiratory chain complex assembly (GO:0033108)2.90159358
44establishment of protein localization to mitochondrial membrane (GO:0090151)2.89010954
45water-soluble vitamin biosynthetic process (GO:0042364)2.86578837
46RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.81674341
47termination of RNA polymerase III transcription (GO:0006386)2.81591401
48transcription elongation from RNA polymerase III promoter (GO:0006385)2.81591401
49DNA demethylation (GO:0080111)2.81530034
50maturation of SSU-rRNA (GO:0030490)2.78023916
51positive regulation of alpha-beta T cell proliferation (GO:0046641)2.77341061
52platelet dense granule organization (GO:0060155)2.75231777
53positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.70499245
54seminiferous tubule development (GO:0072520)2.70345859
55purine nucleotide salvage (GO:0032261)2.70183439
56indolalkylamine metabolic process (GO:0006586)2.69253125
57proteasome assembly (GO:0043248)2.68207877
58translational initiation (GO:0006413)2.68006441
59electron transport chain (GO:0022900)2.67968140
60DNA dealkylation (GO:0035510)2.66226536
61respiratory electron transport chain (GO:0022904)2.65155826
62preassembly of GPI anchor in ER membrane (GO:0016254)2.63981986
63translation (GO:0006412)2.62580186
64purine-containing compound salvage (GO:0043101)2.61914014
65base-excision repair, AP site formation (GO:0006285)2.61293015
66regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.60735908
67GPI anchor metabolic process (GO:0006505)2.60365157
68positive regulation of B cell differentiation (GO:0045579)2.59850794
69positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)2.59106891
70ribosomal small subunit biogenesis (GO:0042274)2.58543065
71response to pheromone (GO:0019236)2.56397424
72fucose catabolic process (GO:0019317)2.56255715
73L-fucose metabolic process (GO:0042354)2.56255715
74L-fucose catabolic process (GO:0042355)2.56255715
75detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.54976608
76viral life cycle (GO:0019058)2.54691265
77cellular protein complex disassembly (GO:0043624)2.53835699
78positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.53787870
79pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.53132304
80mannosylation (GO:0097502)2.51392614
81regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.51083718
82detection of light stimulus involved in sensory perception (GO:0050962)2.50933326
83detection of light stimulus involved in visual perception (GO:0050908)2.50933326
84positive regulation of interleukin-17 production (GO:0032740)2.47297982
85tRNA processing (GO:0008033)2.45703788
86GTP biosynthetic process (GO:0006183)2.45589458
87axoneme assembly (GO:0035082)2.45464808
88male meiosis I (GO:0007141)2.45267382
89aggressive behavior (GO:0002118)2.44469789
90regulation of action potential (GO:0098900)2.43798767
91tryptophan metabolic process (GO:0006568)2.43521687
92estrogen biosynthetic process (GO:0006703)2.43435828
93rRNA processing (GO:0006364)2.42787106
94GPI anchor biosynthetic process (GO:0006506)2.42075083
95rRNA metabolic process (GO:0016072)2.41645750
96L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.41160410
97nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.40670756
98adenosine metabolic process (GO:0046085)2.40156753
99S-adenosylmethionine metabolic process (GO:0046500)2.40031595
100DNA methylation involved in gamete generation (GO:0043046)2.39830562

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1VDR_22108803_ChIP-Seq_LS180_Human3.56495371
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.44638944
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.36969553
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.92061439
5ZNF274_21170338_ChIP-Seq_K562_Hela2.89788637
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.82335662
7ELF1_17652178_ChIP-ChIP_JURKAT_Human2.80260148
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.79323665
9IGF1R_20145208_ChIP-Seq_DFB_Human2.62267912
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.59255828
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.51320519
12EST1_17652178_ChIP-ChIP_JURKAT_Human2.47917970
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.22898775
14VDR_23849224_ChIP-Seq_CD4+_Human2.21591814
15IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.09404286
16NOTCH1_21737748_ChIP-Seq_TLL_Human2.06254970
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.99128222
18ELK1_19687146_ChIP-ChIP_HELA_Human1.90970596
19RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.89921238
20IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.87632821
21ETS1_20019798_ChIP-Seq_JURKAT_Human1.86106111
22EWS_26573619_Chip-Seq_HEK293_Human1.80285694
23FUS_26573619_Chip-Seq_HEK293_Human1.79685061
24IRF8_21731497_ChIP-ChIP_J774_Mouse1.78522073
25MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.77140938
26EZH2_22144423_ChIP-Seq_EOC_Human1.76699513
27FOXP3_21729870_ChIP-Seq_TREG_Human1.74946041
28BP1_19119308_ChIP-ChIP_Hs578T_Human1.74115373
29MYC_18940864_ChIP-ChIP_HL60_Human1.71931998
30EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.69542339
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65722229
32ER_23166858_ChIP-Seq_MCF-7_Human1.63258986
33NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.62941547
34TP53_22573176_ChIP-Seq_HFKS_Human1.58241894
35FOXA1_25329375_ChIP-Seq_VCAP_Human1.57662649
36FOXA1_27270436_Chip-Seq_PROSTATE_Human1.57662649
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.56765688
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55621961
39FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.48551146
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.45448264
41AR_20517297_ChIP-Seq_VCAP_Human1.44230445
42TAF15_26573619_Chip-Seq_HEK293_Human1.43965505
43SRF_21415370_ChIP-Seq_HL-1_Mouse1.42058429
44NCOR_22424771_ChIP-Seq_293T_Human1.40740893
45STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.40505839
46MYB_26560356_Chip-Seq_TH2_Human1.39437590
47P300_19829295_ChIP-Seq_ESCs_Human1.37006988
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36774573
49EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.35495404
50CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.34792708
51MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.34660149
52GATA3_26560356_Chip-Seq_TH2_Human1.33402627
53IRF1_19129219_ChIP-ChIP_H3396_Human1.33161814
54FOXA1_21572438_ChIP-Seq_LNCaP_Human1.32308051
55GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.32149359
56LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.30613172
57CBP_20019798_ChIP-Seq_JUKART_Human1.26732899
58IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.26732899
59NANOG_19829295_ChIP-Seq_ESCs_Human1.26476793
60SOX2_19829295_ChIP-Seq_ESCs_Human1.26476793
61PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.23074095
62GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22279786
63FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.22045967
64CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.19400671
65KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18869038
66GATA3_21878914_ChIP-Seq_MCF-7_Human1.18643043
67BMI1_23680149_ChIP-Seq_NPCS_Mouse1.18522716
68NFE2_27457419_Chip-Seq_LIVER_Mouse1.17113378
69BCAT_22108803_ChIP-Seq_LS180_Human1.16734942
70TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.16215033
71PCGF2_27294783_Chip-Seq_NPCs_Mouse1.14315914
72NANOG_20526341_ChIP-Seq_ESCs_Human1.14199287
73CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.13369736
74FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.12462745
75ETV2_25802403_ChIP-Seq_MESCs_Mouse1.12313251
76UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11931455
77EZH2_27294783_Chip-Seq_NPCs_Mouse1.11608002
78TAF2_19829295_ChIP-Seq_ESCs_Human1.11022780
79GBX2_23144817_ChIP-Seq_PC3_Human1.09971389
80SUZ12_27294783_Chip-Seq_NPCs_Mouse1.09698741
81MYC_18555785_ChIP-Seq_MESCs_Mouse1.08603815
82POU5F1_16153702_ChIP-ChIP_HESCs_Human1.06170435
83ERG_20517297_ChIP-Seq_VCAP_Human1.03914329
84FOXH1_21741376_ChIP-Seq_EPCs_Human1.03680972
85PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.02600539
86GATA3_27048872_Chip-Seq_THYMUS_Human1.01034230
87AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00425597
88SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.97937365
89GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.97847324
90CRX_20693478_ChIP-Seq_RETINA_Mouse0.97036753
91PHF8_20622853_ChIP-Seq_HELA_Human0.96463433
92HOXB7_26014856_ChIP-Seq_BT474_Human0.96165986
93RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.93995683
94PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.93927782
95GATA6_21074721_ChIP-Seq_CACO-2_Human0.93211709
96MYC_19829295_ChIP-Seq_ESCs_Human0.92984420
97EGR1_23403033_ChIP-Seq_LIVER_Mouse0.92932201
98FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.92769633
99EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.92488615
100RBPJ_21746931_ChIP-Seq_IB4_Human0.91825788

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to3.50409002
2MP0006292_abnormal_olfactory_placode2.67054687
3MP0001835_abnormal_antigen_presentation2.57519604
4MP0009379_abnormal_foot_pigmentation2.53953259
5MP0002102_abnormal_ear_morphology2.47673224
6MP0008877_abnormal_DNA_methylation2.25284854
7MP0002837_dystrophic_cardiac_calcinosis2.24750409
8MP0005646_abnormal_pituitary_gland2.24103394
9MP0004147_increased_porphyrin_level2.15697728
10MP0005075_abnormal_melanosome_morpholog2.00647845
11MP0005645_abnormal_hypothalamus_physiol1.99612120
12MP0006072_abnormal_retinal_apoptosis1.98757271
13MP0001873_stomach_inflammation1.96800832
14MP0003806_abnormal_nucleotide_metabolis1.96619942
15MP0008872_abnormal_physiological_respon1.93723893
16MP0003646_muscle_fatigue1.83931528
17MP0002736_abnormal_nociception_after1.83871329
18MP0001968_abnormal_touch/_nociception1.83753689
19MP0008995_early_reproductive_senescence1.82453403
20MP0005551_abnormal_eye_electrophysiolog1.80920056
21MP0009785_altered_susceptibility_to1.75190116
22MP0002148_abnormal_hypersensitivity_rea1.67413791
23MP0009333_abnormal_splenocyte_physiolog1.60165316
24MP0001800_abnormal_humoral_immune1.59903190
25MP0002160_abnormal_reproductive_system1.58976657
26MP0001986_abnormal_taste_sensitivity1.58679727
27MP0004145_abnormal_muscle_electrophysio1.57039483
28MP0003252_abnormal_bile_duct1.56056130
29MP0008058_abnormal_DNA_repair1.54385695
30MP0003011_delayed_dark_adaptation1.51430574
31MP0004885_abnormal_endolymph1.51321860
32MP0005084_abnormal_gallbladder_morpholo1.51139001
33MP0002166_altered_tumor_susceptibility1.49240407
34MP0008875_abnormal_xenobiotic_pharmacok1.48802741
35MP0002138_abnormal_hepatobiliary_system1.48577207
36MP0001764_abnormal_homeostasis1.48373401
37MP0002876_abnormal_thyroid_physiology1.46412831
38MP0003763_abnormal_thymus_physiology1.46065329
39MP0005389_reproductive_system_phenotype1.45381206
40MP0000372_irregular_coat_pigmentation1.44045102
41MP0003195_calcinosis1.40829727
42MP0005000_abnormal_immune_tolerance1.40728905
43MP0002006_tumorigenesis1.40242170
44MP0003786_premature_aging1.36833595
45MP0005253_abnormal_eye_physiology1.31318862
46MP0001790_abnormal_immune_system1.29612548
47MP0005387_immune_system_phenotype1.29612548
48MP0003787_abnormal_imprinting1.29201829
49MP0000685_abnormal_immune_system1.27550114
50MP0002163_abnormal_gland_morphology1.26917603
51MP0002723_abnormal_immune_serum1.25698581
52MP0002420_abnormal_adaptive_immunity1.22407943
53MP0002234_abnormal_pharynx_morphology1.19479446
54MP0001819_abnormal_immune_cell1.19302410
55MP0005410_abnormal_fertilization1.18820794
56MP0004142_abnormal_muscle_tone1.17773182
57MP0006036_abnormal_mitochondrial_physio1.15789121
58MP0002452_abnormal_antigen_presenting1.11067927
59MP0006276_abnormal_autonomic_nervous1.09077979
60MP0001905_abnormal_dopamine_level1.06578553
61MP0002095_abnormal_skin_pigmentation1.05152309
62MP0005025_abnormal_response_to1.03441843
63MP0001919_abnormal_reproductive_system1.01647212
64MP0008789_abnormal_olfactory_epithelium1.01150162
65MP0000678_abnormal_parathyroid_gland1.00517443
66MP0000689_abnormal_spleen_morphology0.99956478
67MP0005636_abnormal_mineral_homeostasis0.99904793
68MP0002693_abnormal_pancreas_physiology0.99732055
69MP0002398_abnormal_bone_marrow0.98465043
70MP0003866_abnormal_defecation0.95514426
71MP0000716_abnormal_immune_system0.94352888
72MP0005360_urolithiasis0.92699400
73MP0003186_abnormal_redox_activity0.92440060
74MP0002272_abnormal_nervous_system0.90919894
75MP0003567_abnormal_fetal_cardiomyocyte0.89805569
76MP0000631_abnormal_neuroendocrine_gland0.88973241
77MP0001485_abnormal_pinna_reflex0.87626751
78MP0001501_abnormal_sleep_pattern0.86971492
79MP0003878_abnormal_ear_physiology0.86947729
80MP0005377_hearing/vestibular/ear_phenot0.86947729
81MP0009745_abnormal_behavioral_response0.84472373
82MP0005670_abnormal_white_adipose0.83375685
83MP0002405_respiratory_system_inflammati0.81831890
84MP0003718_maternal_effect0.80932567
85MP0003880_abnormal_central_pattern0.80024187
86MP0006082_CNS_inflammation0.78783740
87MP0005174_abnormal_tail_pigmentation0.78300089
88MP0002722_abnormal_immune_system0.76990224
89MP0005379_endocrine/exocrine_gland_phen0.76848629
90MP0005332_abnormal_amino_acid0.74976615
91MP0005085_abnormal_gallbladder_physiolo0.74780541
92MP0001963_abnormal_hearing_physiology0.74612432
93MP0001765_abnormal_ion_homeostasis0.74464577
94MP0001845_abnormal_inflammatory_respons0.73910964
95MP0002277_abnormal_respiratory_mucosa0.73577302
96MP0002653_abnormal_ependyma_morphology0.73137087
97MP0001119_abnormal_female_reproductive0.72934380
98MP0002822_catalepsy0.72857064
99MP0000681_abnormal_thyroid_gland0.71940312
100MP0001486_abnormal_startle_reflex0.71928903

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)4.08012328
2Congenital stationary night blindness (HP:0007642)3.81134356
3Abnormal rod and cone electroretinograms (HP:0008323)3.50325321
4Mitochondrial inheritance (HP:0001427)3.42679536
5Acute necrotizing encephalopathy (HP:0006965)3.35418025
6Pancreatic cysts (HP:0001737)3.07348812
7Severe combined immunodeficiency (HP:0004430)3.06807138
8Increased CSF lactate (HP:0002490)3.06153143
9IgG deficiency (HP:0004315)3.03269702
103-Methylglutaconic aciduria (HP:0003535)3.03027291
11Acute encephalopathy (HP:0006846)3.00919491
12Abolished electroretinogram (ERG) (HP:0000550)3.00585956
13Abnormality of the prostate (HP:0008775)2.99966787
14Elevated erythrocyte sedimentation rate (HP:0003565)2.94347257
15Hypoproteinemia (HP:0003075)2.91871096
16Abnormality of B cell number (HP:0010975)2.90395037
17Renal Fanconi syndrome (HP:0001994)2.89804461
18Increased hepatocellular lipid droplets (HP:0006565)2.89220142
19Abnormal mitochondria in muscle tissue (HP:0008316)2.89112856
20Decreased electroretinogram (ERG) amplitude (HP:0000654)2.88858575
21Hepatocellular necrosis (HP:0001404)2.84211325
22Molar tooth sign on MRI (HP:0002419)2.81609982
23Abnormality of midbrain morphology (HP:0002418)2.81609982
24Aplastic anemia (HP:0001915)2.81008985
25Constricted visual fields (HP:0001133)2.80950372
26Attenuation of retinal blood vessels (HP:0007843)2.80711106
27Progressive macrocephaly (HP:0004481)2.79141395
28Lipid accumulation in hepatocytes (HP:0006561)2.77401388
29Pancreatic fibrosis (HP:0100732)2.77276106
30True hermaphroditism (HP:0010459)2.73559366
31Hepatic necrosis (HP:0002605)2.71942544
32Reticulocytopenia (HP:0001896)2.70185126
33Thyroiditis (HP:0100646)2.67356263
34Decreased central vision (HP:0007663)2.67110600
35Stenosis of the external auditory canal (HP:0000402)2.65068973
36B lymphocytopenia (HP:0010976)2.63108074
37Pendular nystagmus (HP:0012043)2.56535912
38Cerebral edema (HP:0002181)2.48959718
39Optic disc pallor (HP:0000543)2.47307998
40Stomatitis (HP:0010280)2.46328622
41Renal cortical cysts (HP:0000803)2.43868012
42Increased intramyocellular lipid droplets (HP:0012240)2.42406295
43Panhypogammaglobulinemia (HP:0003139)2.41746949
44Methylmalonic acidemia (HP:0002912)2.40549197
45Prostate neoplasm (HP:0100787)2.39246961
46Medial flaring of the eyebrow (HP:0010747)2.38815600
47Autoimmune hemolytic anemia (HP:0001890)2.36012446
48Nephronophthisis (HP:0000090)2.33096605
49Abnormality of T cell number (HP:0011839)2.31575861
50Combined immunodeficiency (HP:0005387)2.30338243
51Abnormality of the renal collecting system (HP:0004742)2.28354372
52T lymphocytopenia (HP:0005403)2.26543985
53Abnormality of the renal cortex (HP:0011035)2.24647165
54Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.24387877
55Abnormality of alanine metabolism (HP:0010916)2.24387877
56Hyperalaninemia (HP:0003348)2.24387877
57Abnormality of cells of the erythroid lineage (HP:0012130)2.21424497
58Hyperglycinemia (HP:0002154)2.19766046
59Increased serum lactate (HP:0002151)2.19309482
60Type 2 muscle fiber atrophy (HP:0003554)2.18915136
61Abnormality of T cells (HP:0002843)2.15959781
62Generalized aminoaciduria (HP:0002909)2.15552662
63Genetic anticipation (HP:0003743)2.15524178
64Abnormality of urine glucose concentration (HP:0011016)2.15343839
65Glycosuria (HP:0003076)2.15343839
66Dynein arm defect of respiratory motile cilia (HP:0012255)2.10235891
67Absent/shortened dynein arms (HP:0200106)2.10235891
68Aplasia/Hypoplasia of the spleen (HP:0010451)2.09643979
69Lactic acidosis (HP:0003128)2.09617317
70Asplenia (HP:0001746)2.04101332
71Increased muscle lipid content (HP:0009058)2.02808119
72Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.02059302
73Increased IgM level (HP:0003496)2.01829325
74Macrocytic anemia (HP:0001972)2.01086614
75Lethargy (HP:0001254)1.98413994
76Exertional dyspnea (HP:0002875)1.97451388
77Keratoconus (HP:0000563)1.97331675
78Increased corneal curvature (HP:0100692)1.97331675
79Abnormality of eosinophils (HP:0001879)1.97015354
80Abnormality of macular pigmentation (HP:0008002)1.96650107
81Severe visual impairment (HP:0001141)1.96430572
82Abnormality of DNA repair (HP:0003254)1.96328315
83Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.96281580
84Absent thumb (HP:0009777)1.94619361
85Abnormal drinking behavior (HP:0030082)1.88843354
86Polydipsia (HP:0001959)1.88843354
87Abnormal number of erythroid precursors (HP:0012131)1.88666913
88Abnormality of the renal medulla (HP:0100957)1.85357941
89Pancytopenia (HP:0001876)1.83091678
90Methylmalonic aciduria (HP:0012120)1.82291679
91Abnormality of male internal genitalia (HP:0000022)1.80811585
92Ketosis (HP:0001946)1.77691639
93Type I transferrin isoform profile (HP:0003642)1.75788329
94Hyperglycinuria (HP:0003108)1.74563515
95Abnormality of renal resorption (HP:0011038)1.74087304
96Agammaglobulinemia (HP:0004432)1.73727008
97Abnormality of T cell physiology (HP:0011840)1.73367183
98Abnormality of serum amino acid levels (HP:0003112)1.72768496
99Reduced antithrombin III activity (HP:0001976)1.70551967
100Dyschromatopsia (HP:0007641)1.70524417

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK194.31648561
2TXK3.90993721
3BCKDK3.70798119
4FRK2.90005950
5GRK12.84917185
6TAOK32.66174157
7VRK22.41170814
8ZAK2.40780655
9NUAK12.36928695
10ADRBK22.34983607
11KDR2.14220453
12EIF2AK32.09572503
13MAP4K22.00819420
14PINK11.93934688
15OXSR11.89935770
16TLK11.73584171
17BMPR1B1.69966801
18TEC1.67646690
19PASK1.65069742
20KIT1.60066674
21VRK11.58079206
22TESK21.53942324
23ITK1.52140311
24TIE11.29280389
25FLT31.26975208
26MST41.24675148
27MAP4K11.23978404
28SCYL21.21126583
29SYK1.19563828
30TNK21.16144304
31MAP3K121.15337128
32WNK31.12468813
33WNK41.10417377
34MUSK1.05501715
35INSRR1.04555960
36STK160.98668920
37DAPK10.93416453
38IKBKB0.91881376
39BTK0.91325599
40ACVR1B0.91001077
41GRK60.89573117
42PRKCQ0.87964365
43BMPR20.87233299
44FES0.82186574
45CSF1R0.80957154
46STK390.75236273
47PIK3CG0.74368770
48DYRK20.74347810
49MAP2K60.73006168
50RPS6KB20.71068774
51TRPM70.70888819
52ADRBK10.70551814
53LCK0.66724316
54LYN0.64552866
55CAMKK20.64509074
56MKNK10.63719922
57DAPK20.63705383
58OBSCN0.62987433
59BRSK20.61359400
60MAPK130.59331171
61MKNK20.57820199
62PBK0.57367294
63MATK0.53467162
64MYLK0.53283028
65EIF2AK20.52915588
66MAPKAPK30.50440804
67IGF1R0.49159633
68ERBB30.49088888
69TGFBR10.49004965
70CSNK1G10.48611100
71PRKCE0.48108586
72DAPK30.47977865
73MAPKAPK50.46173552
74PIM10.44612536
75GRK70.43769440
76IKBKE0.43680845
77PLK40.42593614
78MAP2K70.42284283
79TRIM280.42181545
80CDK30.42021309
81PRKACA0.41705631
82PRKCA0.41493216
83RPS6KA50.41398655
84NLK0.40857198
85JAK30.40678603
86PIK3CA0.40591132
87TAF10.40455033
88PRKCG0.40296028
89EIF2AK10.38088146
90CSNK1G30.37951254
91CSNK2A10.37833075
92CSNK2A20.37432828
93PLK30.37205162
94MAP3K40.36869252
95CSNK1A10.35517398
96MAP3K110.34875074
97NME10.34384992
98RPS6KA40.33797625
99PRKCD0.33097841
100CAMKK10.31454393

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.44574276
2Primary immunodeficiency_Homo sapiens_hsa053403.16354230
3Proteasome_Homo sapiens_hsa030502.92787877
4Oxidative phosphorylation_Homo sapiens_hsa001902.83276910
5Asthma_Homo sapiens_hsa053102.70051650
6Allograft rejection_Homo sapiens_hsa053302.60553871
7Autoimmune thyroid disease_Homo sapiens_hsa053202.44211589
8Graft-versus-host disease_Homo sapiens_hsa053322.34687205
9Intestinal immune network for IgA production_Homo sapiens_hsa046722.31117970
10Parkinsons disease_Homo sapiens_hsa050122.23402233
11Type I diabetes mellitus_Homo sapiens_hsa049402.18856557
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.08108772
13RNA polymerase_Homo sapiens_hsa030202.07793129
14Protein export_Homo sapiens_hsa030601.98030916
15Phototransduction_Homo sapiens_hsa047441.91122489
16Linoleic acid metabolism_Homo sapiens_hsa005911.73310391
17Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.69438443
18Antigen processing and presentation_Homo sapiens_hsa046121.65724378
19Homologous recombination_Homo sapiens_hsa034401.62802738
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.62115923
21Propanoate metabolism_Homo sapiens_hsa006401.57375029
22RNA degradation_Homo sapiens_hsa030181.52550486
23alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.44670952
24Hematopoietic cell lineage_Homo sapiens_hsa046401.44666057
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.41902629
26One carbon pool by folate_Homo sapiens_hsa006701.37783021
27Alzheimers disease_Homo sapiens_hsa050101.36974338
28Primary bile acid biosynthesis_Homo sapiens_hsa001201.34619650
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34106595
30Huntingtons disease_Homo sapiens_hsa050161.32651408
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.30107067
32Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.28003561
33Fanconi anemia pathway_Homo sapiens_hsa034601.24735828
34Butanoate metabolism_Homo sapiens_hsa006501.23650808
35Caffeine metabolism_Homo sapiens_hsa002321.23569123
36Olfactory transduction_Homo sapiens_hsa047401.22001319
37Nitrogen metabolism_Homo sapiens_hsa009101.21931822
38Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.21787506
39Cardiac muscle contraction_Homo sapiens_hsa042601.21135777
40Pyrimidine metabolism_Homo sapiens_hsa002401.16507434
41Rheumatoid arthritis_Homo sapiens_hsa053231.15049424
42Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12642546
43Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.12294838
44Maturity onset diabetes of the young_Homo sapiens_hsa049501.12220921
45Retinol metabolism_Homo sapiens_hsa008301.11830212
46Basal transcription factors_Homo sapiens_hsa030221.08304631
47Steroid hormone biosynthesis_Homo sapiens_hsa001401.06617405
48Ether lipid metabolism_Homo sapiens_hsa005651.05170773
49Peroxisome_Homo sapiens_hsa041461.03879746
50Purine metabolism_Homo sapiens_hsa002300.99190587
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.97479971
52Chemical carcinogenesis_Homo sapiens_hsa052040.94353541
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.94336542
54Nucleotide excision repair_Homo sapiens_hsa034200.92412239
55Tryptophan metabolism_Homo sapiens_hsa003800.90836608
56Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.88225444
57Arachidonic acid metabolism_Homo sapiens_hsa005900.86986939
58Base excision repair_Homo sapiens_hsa034100.86690438
59Mismatch repair_Homo sapiens_hsa034300.85757102
60Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.79159344
61Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.78045773
62Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.77637651
63Regulation of autophagy_Homo sapiens_hsa041400.74684896
64Drug metabolism - other enzymes_Homo sapiens_hsa009830.73832912
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.72099929
66RNA transport_Homo sapiens_hsa030130.70947242
67Non-homologous end-joining_Homo sapiens_hsa034500.69437849
68SNARE interactions in vesicular transport_Homo sapiens_hsa041300.68659888
69Taste transduction_Homo sapiens_hsa047420.68101572
70Pentose and glucuronate interconversions_Homo sapiens_hsa000400.66463191
71Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.63888742
72T cell receptor signaling pathway_Homo sapiens_hsa046600.63467669
73Metabolic pathways_Homo sapiens_hsa011000.62842018
74Selenocompound metabolism_Homo sapiens_hsa004500.62702333
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60215690
76Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.60007593
77Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57291876
78DNA replication_Homo sapiens_hsa030300.56004976
79Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.55092001
80Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.53609380
81Spliceosome_Homo sapiens_hsa030400.53532310
82Viral myocarditis_Homo sapiens_hsa054160.51775364
83Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.51222023
84Systemic lupus erythematosus_Homo sapiens_hsa053220.49284435
85Nicotine addiction_Homo sapiens_hsa050330.46243050
86Collecting duct acid secretion_Homo sapiens_hsa049660.43587489
87Fat digestion and absorption_Homo sapiens_hsa049750.43058681
88Salivary secretion_Homo sapiens_hsa049700.39955382
89Sulfur relay system_Homo sapiens_hsa041220.39819745
90NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38720963
91NF-kappa B signaling pathway_Homo sapiens_hsa040640.35247484
92Sulfur metabolism_Homo sapiens_hsa009200.35114168
93Fatty acid elongation_Homo sapiens_hsa000620.32799791
94Ovarian steroidogenesis_Homo sapiens_hsa049130.30593858
95Staphylococcus aureus infection_Homo sapiens_hsa051500.30307305
96Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.29297845
97Morphine addiction_Homo sapiens_hsa050320.28008800
98Herpes simplex infection_Homo sapiens_hsa051680.27534119
99Measles_Homo sapiens_hsa051620.27213223
100N-Glycan biosynthesis_Homo sapiens_hsa005100.25561117

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »