RPS3AP47

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.82042093
2viral transcription (GO:0019083)5.58136668
3DNA deamination (GO:0045006)5.50628964
4translational termination (GO:0006415)5.37478662
5translational elongation (GO:0006414)4.77724063
6SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.76808118
7cotranslational protein targeting to membrane (GO:0006613)4.68026119
8protein targeting to ER (GO:0045047)4.65505787
9maturation of SSU-rRNA (GO:0030490)4.60390095
10ATP synthesis coupled proton transport (GO:0015986)4.58940775
11energy coupled proton transport, down electrochemical gradient (GO:0015985)4.58940775
12regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.52584048
13establishment of protein localization to endoplasmic reticulum (GO:0072599)4.44664083
14protein localization to endoplasmic reticulum (GO:0070972)4.43069784
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.36679098
16cytidine metabolic process (GO:0046087)4.36427132
17cytidine catabolic process (GO:0006216)4.36427132
18cytidine deamination (GO:0009972)4.36427132
19behavioral response to nicotine (GO:0035095)4.33581911
20ribosomal small subunit biogenesis (GO:0042274)4.14882406
21protein neddylation (GO:0045116)4.05807268
22ribosomal large subunit biogenesis (GO:0042273)4.04287576
23cellular protein complex disassembly (GO:0043624)3.99053219
24viral life cycle (GO:0019058)3.95748532
25pyrimidine ribonucleoside catabolic process (GO:0046133)3.78353646
26nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.77611809
27mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.74219993
28translational initiation (GO:0006413)3.64411572
29tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.47490525
30RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.47490525
31protein complex biogenesis (GO:0070271)3.44950288
32electron transport chain (GO:0022900)3.36275992
33respiratory electron transport chain (GO:0022904)3.34588419
34translation (GO:0006412)3.28216643
35mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.27609108
36mitochondrial respiratory chain complex I assembly (GO:0032981)3.27609108
37NADH dehydrogenase complex assembly (GO:0010257)3.27609108
38protein complex disassembly (GO:0043241)3.24301878
39macromolecular complex disassembly (GO:0032984)3.15615057
40axoneme assembly (GO:0035082)3.14940227
41mitochondrial respiratory chain complex assembly (GO:0033108)3.04443128
42nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.01996800
43protein targeting to membrane (GO:0006612)2.99907285
44establishment of protein localization to mitochondrial membrane (GO:0090151)2.99281782
45GPI anchor metabolic process (GO:0006505)2.97993030
46epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.96005183
47chaperone-mediated protein transport (GO:0072321)2.90848832
48exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.89903495
49response to pheromone (GO:0019236)2.89204223
50GPI anchor biosynthetic process (GO:0006506)2.86638541
51nuclear-transcribed mRNA catabolic process (GO:0000956)2.84906172
52mannosylation (GO:0097502)2.83377594
53water-soluble vitamin biosynthetic process (GO:0042364)2.79431742
54positive regulation of defense response to virus by host (GO:0002230)2.77465443
55preassembly of GPI anchor in ER membrane (GO:0016254)2.77399340
56termination of RNA polymerase III transcription (GO:0006386)2.73722399
57transcription elongation from RNA polymerase III promoter (GO:0006385)2.73722399
58cellular component biogenesis (GO:0044085)2.70239730
59negative regulation of mast cell activation (GO:0033004)2.70029860
60platelet dense granule organization (GO:0060155)2.69816856
61hydrogen ion transmembrane transport (GO:1902600)2.68296999
62mRNA catabolic process (GO:0006402)2.67575283
63kynurenine metabolic process (GO:0070189)2.65633901
64positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)2.65541505
65GTP biosynthetic process (GO:0006183)2.64751719
66protein polyglutamylation (GO:0018095)2.64279367
67negative regulation of telomere maintenance (GO:0032205)2.62405262
68purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.62286494
69ATP biosynthetic process (GO:0006754)2.61508002
70proton transport (GO:0015992)2.59828567
71purine nucleoside triphosphate biosynthetic process (GO:0009145)2.59792172
72indole-containing compound catabolic process (GO:0042436)2.59116298
73indolalkylamine catabolic process (GO:0046218)2.59116298
74tryptophan catabolic process (GO:0006569)2.59116298
75piRNA metabolic process (GO:0034587)2.57339859
76ubiquinone biosynthetic process (GO:0006744)2.57287206
77pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.55785745
78hydrogen transport (GO:0006818)2.55281280
79ribonucleoprotein complex biogenesis (GO:0022613)2.54638414
80positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.54407702
81indolalkylamine metabolic process (GO:0006586)2.52069512
82metallo-sulfur cluster assembly (GO:0031163)2.51283964
83iron-sulfur cluster assembly (GO:0016226)2.51283964
84regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.50505614
85mast cell activation (GO:0045576)2.49347318
86regulation of action potential (GO:0098900)2.46909055
87base-excision repair, AP site formation (GO:0006285)2.46356758
88mast cell degranulation (GO:0043303)2.45731088
89mast cell activation involved in immune response (GO:0002279)2.45731088
90regulation of regulatory T cell differentiation (GO:0045589)2.44218774
91RNA catabolic process (GO:0006401)2.43985668
92L-fucose catabolic process (GO:0042355)2.43546254
93fucose catabolic process (GO:0019317)2.43546254
94L-fucose metabolic process (GO:0042354)2.43546254
95regulation of cilium movement (GO:0003352)2.42452380
96regulation of isotype switching to IgG isotypes (GO:0048302)2.39949130
97negative regulation of appetite (GO:0032099)2.39823958
98negative regulation of response to food (GO:0032096)2.39823958
99detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.38780981
100parturition (GO:0007567)2.38643445

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.64058298
2VDR_22108803_ChIP-Seq_LS180_Human3.42236532
3GABP_17652178_ChIP-ChIP_JURKAT_Human3.40129548
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.00004230
5ELF1_17652178_ChIP-ChIP_JURKAT_Human2.76836655
6ZNF274_21170338_ChIP-Seq_K562_Hela2.68759179
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.66713897
8KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.64320543
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.57005929
10HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.51824420
11IGF1R_20145208_ChIP-Seq_DFB_Human2.16832519
12VDR_23849224_ChIP-Seq_CD4+_Human2.16631848
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.09973738
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.00505301
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.99885112
16ETS1_20019798_ChIP-Seq_JURKAT_Human1.99623436
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97612506
18FLI1_27457419_Chip-Seq_LIVER_Mouse1.97352133
19IRF8_22096565_ChIP-ChIP_GC-B_Human1.94932739
20IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.91518062
21BP1_19119308_ChIP-ChIP_Hs578T_Human1.91241334
22TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.88596870
23NOTCH1_21737748_ChIP-Seq_TLL_Human1.75321795
24MYC_18940864_ChIP-ChIP_HL60_Human1.74032349
25STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.73891929
26EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.71144013
27IRF1_19129219_ChIP-ChIP_H3396_Human1.68784368
28CTBP1_25329375_ChIP-Seq_LNCAP_Human1.68413053
29ELK1_19687146_ChIP-ChIP_HELA_Human1.60250048
30TP53_22573176_ChIP-Seq_HFKS_Human1.59712345
31FOXP3_21729870_ChIP-Seq_TREG_Human1.59366265
32PCGF2_27294783_Chip-Seq_ESCs_Mouse1.56216533
33EWS_26573619_Chip-Seq_HEK293_Human1.55372415
34BMI1_23680149_ChIP-Seq_NPCS_Mouse1.52243656
35NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.50581971
36FUS_26573619_Chip-Seq_HEK293_Human1.46232070
37RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.45444709
38FOXA1_27270436_Chip-Seq_PROSTATE_Human1.43589262
39FOXA1_25329375_ChIP-Seq_VCAP_Human1.43589262
40AR_20517297_ChIP-Seq_VCAP_Human1.41144303
41NCOR_22424771_ChIP-Seq_293T_Human1.37112377
42SRF_21415370_ChIP-Seq_HL-1_Mouse1.36358962
43LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.35663831
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.34057218
45MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.33221198
46NANOG_20526341_ChIP-Seq_ESCs_Human1.32958280
47GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.28994061
48ER_23166858_ChIP-Seq_MCF-7_Human1.28731271
49CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.28567385
50CBP_20019798_ChIP-Seq_JUKART_Human1.25932166
51IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25932166
52CTBP2_25329375_ChIP-Seq_LNCAP_Human1.25410874
53CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.25020350
54P300_19829295_ChIP-Seq_ESCs_Human1.24589849
55GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23662213
56PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21368973
57CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.21143190
58GATA3_21878914_ChIP-Seq_MCF-7_Human1.21101816
59TAF2_19829295_ChIP-Seq_ESCs_Human1.19513393
60ETV2_25802403_ChIP-Seq_MESCs_Mouse1.19296280
61AUTS2_25519132_ChIP-Seq_293T-REX_Human1.19291644
62SOX2_19829295_ChIP-Seq_ESCs_Human1.18925306
63NANOG_19829295_ChIP-Seq_ESCs_Human1.18925306
64GATA3_26560356_Chip-Seq_TH2_Human1.18482750
65IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.17698291
66PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.17303485
67RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.15197168
68CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.10852313
69PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.10685347
70MYC_18555785_ChIP-Seq_MESCs_Mouse1.08843982
71EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.07973097
72CBX2_27304074_Chip-Seq_ESCs_Mouse1.07425620
73KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07291704
74FOXA1_21572438_ChIP-Seq_LNCaP_Human1.05177495
75NFE2_27457419_Chip-Seq_LIVER_Mouse1.04844344
76ERA_21632823_ChIP-Seq_H3396_Human1.03511352
77MYC_19829295_ChIP-Seq_ESCs_Human1.03385120
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02920424
79RNF2_27304074_Chip-Seq_NSC_Mouse1.02163019
80TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.01958678
81POU5F1_16153702_ChIP-ChIP_HESCs_Human1.00620359
82TAF15_26573619_Chip-Seq_HEK293_Human1.00611624
83GBX2_23144817_ChIP-Seq_PC3_Human0.98125091
84FOXH1_21741376_ChIP-Seq_EPCs_Human0.96891427
85POU3F2_20337985_ChIP-ChIP_501MEL_Human0.96538930
86P53_21459846_ChIP-Seq_SAOS-2_Human0.96212055
87TDRD3_21172665_ChIP-Seq_MCF-7_Human0.95864063
88JARID2_20064375_ChIP-Seq_MESCs_Mouse0.95778436
89ERG_20517297_ChIP-Seq_VCAP_Human0.95759425
90SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95624610
91MYB_26560356_Chip-Seq_TH2_Human0.95066173
92TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94022879
93RUNX_20019798_ChIP-Seq_JUKART_Human0.93867246
94FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.92884127
95FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92717789
96HOXB7_26014856_ChIP-Seq_BT474_Human0.92128998
97REST_21632747_ChIP-Seq_MESCs_Mouse0.91132852
98CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.90994985
99PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.89791493
100ELK1_22589737_ChIP-Seq_MCF10A_Human0.89746372

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.49749985
2MP0005671_abnormal_response_to3.52583123
3MP0006292_abnormal_olfactory_placode3.46762441
4MP0006072_abnormal_retinal_apoptosis2.29481943
5MP0008877_abnormal_DNA_methylation2.16869372
6MP0001835_abnormal_antigen_presentation2.14398937
7MP0004147_increased_porphyrin_level2.13147930
8MP0002102_abnormal_ear_morphology2.06650374
9MP0003646_muscle_fatigue1.94523864
10MP0008872_abnormal_physiological_respon1.93575337
11MP0005551_abnormal_eye_electrophysiolog1.90137459
12MP0005645_abnormal_hypothalamus_physiol1.86594067
13MP0004142_abnormal_muscle_tone1.86265492
14MP0003787_abnormal_imprinting1.85075033
15MP0003878_abnormal_ear_physiology1.83687502
16MP0005377_hearing/vestibular/ear_phenot1.83687502
17MP0002653_abnormal_ependyma_morphology1.78872868
18MP0005646_abnormal_pituitary_gland1.76605815
19MP0002163_abnormal_gland_morphology1.76071724
20MP0002837_dystrophic_cardiac_calcinosis1.74592334
21MP0009785_altered_susceptibility_to1.68605070
22MP0001986_abnormal_taste_sensitivity1.65046881
23MP0004145_abnormal_muscle_electrophysio1.64627615
24MP0001968_abnormal_touch/_nociception1.63917638
25MP0004885_abnormal_endolymph1.63266337
26MP0008875_abnormal_xenobiotic_pharmacok1.62668109
27MP0002876_abnormal_thyroid_physiology1.58078800
28MP0005389_reproductive_system_phenotype1.53009911
29MP0005084_abnormal_gallbladder_morpholo1.52834362
30MP0002138_abnormal_hepatobiliary_system1.50802070
31MP0002160_abnormal_reproductive_system1.44757968
32MP0006276_abnormal_autonomic_nervous1.44044269
33MP0001800_abnormal_humoral_immune1.41366800
34MP0005075_abnormal_melanosome_morpholog1.40189081
35MP0000372_irregular_coat_pigmentation1.40094127
36MP0002272_abnormal_nervous_system1.36342465
37MP0008789_abnormal_olfactory_epithelium1.34558716
38MP0005253_abnormal_eye_physiology1.33972960
39MP0001873_stomach_inflammation1.32233464
40MP0002736_abnormal_nociception_after1.32056874
41MP0001485_abnormal_pinna_reflex1.31666213
42MP0001905_abnormal_dopamine_level1.30678661
43MP0002148_abnormal_hypersensitivity_rea1.29493949
44MP0003011_delayed_dark_adaptation1.28289409
45MP0005000_abnormal_immune_tolerance1.25406434
46MP0001919_abnormal_reproductive_system1.24760684
47MP0009333_abnormal_splenocyte_physiolog1.19521653
48MP0003880_abnormal_central_pattern1.18388843
49MP0002095_abnormal_skin_pigmentation1.18346385
50MP0002638_abnormal_pupillary_reflex1.17452511
51MP0002723_abnormal_immune_serum1.16544279
52MP0000685_abnormal_immune_system1.15980519
53MP0003763_abnormal_thymus_physiology1.15021506
54MP0001188_hyperpigmentation1.13587700
55MP0001293_anophthalmia1.11322373
56MP0003195_calcinosis1.09779267
57MP0001790_abnormal_immune_system1.08753489
58MP0005387_immune_system_phenotype1.08753489
59MP0009745_abnormal_behavioral_response1.07082357
60MP0000631_abnormal_neuroendocrine_gland1.06956056
61MP0002234_abnormal_pharynx_morphology1.05365986
62MP0005174_abnormal_tail_pigmentation1.04884656
63MP0002420_abnormal_adaptive_immunity1.04609279
64MP0001819_abnormal_immune_cell1.02808124
65MP0001501_abnormal_sleep_pattern1.01548681
66MP0003866_abnormal_defecation1.00310962
67MP0005379_endocrine/exocrine_gland_phen0.99862600
68MP0008995_early_reproductive_senescence0.99672969
69MP0001984_abnormal_olfaction0.99595526
70MP0001970_abnormal_pain_threshold0.99564789
71MP0001529_abnormal_vocalization0.97633281
72MP0002452_abnormal_antigen_presenting0.94295804
73MP0004742_abnormal_vestibular_system0.94046433
74MP0005025_abnormal_response_to0.93498085
75MP0003567_abnormal_fetal_cardiomyocyte0.93096971
76MP0009764_decreased_sensitivity_to0.92884444
77MP0002733_abnormal_thermal_nociception0.90551287
78MP0003122_maternal_imprinting0.88442828
79MP0005195_abnormal_posterior_eye0.88205427
80MP0001486_abnormal_startle_reflex0.87172355
81MP0002166_altered_tumor_susceptibility0.84925070
82MP0010386_abnormal_urinary_bladder0.83988656
83MP0001440_abnormal_grooming_behavior0.82510840
84MP0005410_abnormal_fertilization0.82439270
85MP0002735_abnormal_chemical_nociception0.82092238
86MP0002006_tumorigenesis0.80626958
87MP0002277_abnormal_respiratory_mucosa0.80539377
88MP0003121_genomic_imprinting0.79993745
89MP0001963_abnormal_hearing_physiology0.78609556
90MP0001765_abnormal_ion_homeostasis0.78224251
91MP0005636_abnormal_mineral_homeostasis0.77407384
92MP0005499_abnormal_olfactory_system0.77178740
93MP0005394_taste/olfaction_phenotype0.77178740
94MP0000049_abnormal_middle_ear0.77154618
95MP0000716_abnormal_immune_system0.77060421
96MP0003806_abnormal_nucleotide_metabolis0.77014108
97MP0002928_abnormal_bile_duct0.76679427
98MP0001348_abnormal_lacrimal_gland0.76267076
99MP0000026_abnormal_inner_ear0.74315007
100MP0003136_yellow_coat_color0.74284799

Predicted human phenotypes

RankGene SetZ-score
1Absent rod-and cone-mediated responses on ERG (HP:0007688)4.36982381
2Acute necrotizing encephalopathy (HP:0006965)3.84380264
3Congenital stationary night blindness (HP:0007642)3.77537054
4Abnormal rod and cone electroretinograms (HP:0008323)3.58975253
5Reticulocytopenia (HP:0001896)3.51170779
6Mitochondrial inheritance (HP:0001427)3.49780771
7Abnormality of cells of the erythroid lineage (HP:0012130)3.44847407
8Pancreatic cysts (HP:0001737)3.44029604
9Abnormal mitochondria in muscle tissue (HP:0008316)3.43490536
10Abnormality of midbrain morphology (HP:0002418)3.41438951
11Molar tooth sign on MRI (HP:0002419)3.41438951
12Pancreatic fibrosis (HP:0100732)3.32740368
13IgG deficiency (HP:0004315)3.24844737
14Acute encephalopathy (HP:0006846)3.24067449
15Progressive macrocephaly (HP:0004481)3.16073094
16Increased CSF lactate (HP:0002490)3.06418849
17True hermaphroditism (HP:0010459)3.03129407
18Elevated erythrocyte sedimentation rate (HP:0003565)3.02919250
19Hepatocellular necrosis (HP:0001404)3.01219799
20Aplastic anemia (HP:0001915)3.00224612
21Abolished electroretinogram (ERG) (HP:0000550)2.97380375
223-Methylglutaconic aciduria (HP:0003535)2.94233674
23Abnormal number of erythroid precursors (HP:0012131)2.88004505
24Severe combined immunodeficiency (HP:0004430)2.87675163
25Medial flaring of the eyebrow (HP:0010747)2.74984868
26Nephronophthisis (HP:0000090)2.74934695
27Hepatic necrosis (HP:0002605)2.73288171
28Absent/shortened dynein arms (HP:0200106)2.63460251
29Dynein arm defect of respiratory motile cilia (HP:0012255)2.63460251
30Macrocytic anemia (HP:0001972)2.63283241
31Increased hepatocellular lipid droplets (HP:0006565)2.60227775
32Optic disc pallor (HP:0000543)2.55241206
33Type II lissencephaly (HP:0007260)2.46428465
34Lipid accumulation in hepatocytes (HP:0006561)2.45423183
35Cerebral edema (HP:0002181)2.43134966
36Renal Fanconi syndrome (HP:0001994)2.43126993
37Thyroiditis (HP:0100646)2.39819872
38Hypoproteinemia (HP:0003075)2.39654316
39Attenuation of retinal blood vessels (HP:0007843)2.39332666
40Aplasia/Hypoplasia of the spleen (HP:0010451)2.38367228
41Pendular nystagmus (HP:0012043)2.37490182
42Asplenia (HP:0001746)2.36590703
43Abnormality of the renal cortex (HP:0011035)2.36416238
44Decreased central vision (HP:0007663)2.33714535
45Absent thumb (HP:0009777)2.31653640
46Stenosis of the external auditory canal (HP:0000402)2.30375242
47Abnormality of the renal medulla (HP:0100957)2.28255864
48Abnormality of B cell number (HP:0010975)2.27772306
49Stomatitis (HP:0010280)2.26270477
50Pallor (HP:0000980)2.25589947
51Constricted visual fields (HP:0001133)2.24998823
52Decreased electroretinogram (ERG) amplitude (HP:0000654)2.24575111
53Increased intramyocellular lipid droplets (HP:0012240)2.21830941
54Congenital, generalized hypertrichosis (HP:0004540)2.21608997
55Sclerocornea (HP:0000647)2.17786999
56Increased IgM level (HP:0003496)2.17515823
57Cystic liver disease (HP:0006706)2.16492591
58Renal cortical cysts (HP:0000803)2.15978777
59Type 2 muscle fiber atrophy (HP:0003554)2.15206279
60T lymphocytopenia (HP:0005403)2.13815591
61Gait imbalance (HP:0002141)2.11725807
62Polydipsia (HP:0001959)2.11541055
63Abnormal drinking behavior (HP:0030082)2.11541055
64Abnormality of T cell number (HP:0011839)2.11264492
65Congenital primary aphakia (HP:0007707)2.10886438
66Increased serum lactate (HP:0002151)2.10072120
67Abnormal respiratory motile cilium morphology (HP:0005938)2.07304834
68Abnormal respiratory epithelium morphology (HP:0012253)2.07304834
69Combined immunodeficiency (HP:0005387)2.04798544
70Methylmalonic acidemia (HP:0002912)2.04595354
71Abnormal respiratory motile cilium physiology (HP:0012261)2.03141079
72Abnormal ciliary motility (HP:0012262)2.02559407
73Nephrogenic diabetes insipidus (HP:0009806)2.01179784
74B lymphocytopenia (HP:0010976)1.97919908
75Generalized aminoaciduria (HP:0002909)1.95698943
76Septo-optic dysplasia (HP:0100842)1.95224450
77Lactic acidosis (HP:0003128)1.94788393
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.94086091
79Abnormality of DNA repair (HP:0003254)1.93929313
80Abnormality of the prostate (HP:0008775)1.92794900
81Keratoconus (HP:0000563)1.91158281
82Increased corneal curvature (HP:0100692)1.91158281
83Decreased activity of mitochondrial respiratory chain (HP:0008972)1.90904413
84Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.90904413
85Rib fusion (HP:0000902)1.89466449
86Abnormality of T cells (HP:0002843)1.88291134
87Lethargy (HP:0001254)1.87901194
88Exertional dyspnea (HP:0002875)1.87576340
89Chronic hepatic failure (HP:0100626)1.87112545
90Panhypogammaglobulinemia (HP:0003139)1.85501331
91Abnormality of eosinophils (HP:0001879)1.83810086
92Polyuria (HP:0000103)1.83442099
93Increased muscle lipid content (HP:0009058)1.82272324
94Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.81409907
95Pancytopenia (HP:0001876)1.79106141
96Abnormality of the renal collecting system (HP:0004742)1.78381777
97Hyperglycinemia (HP:0002154)1.74666798
98Male pseudohermaphroditism (HP:0000037)1.74280512
99Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.74045366
100Glycosuria (HP:0003076)1.73202090

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.36809681
2CDK193.17043524
3TAOK32.90586849
4MAP4K22.75552899
5ADRBK22.74631672
6BCKDK2.63533863
7ZAK2.63218001
8KDR2.53356610
9TLK12.50230439
10GRK12.42015251
11NUAK12.22006446
12FRK2.11512398
13VRK22.00466014
14PINK11.98150896
15WNK41.95352399
16STK161.90531581
17TESK21.85779000
18MAP4K11.59801850
19KIT1.47314778
20WNK31.45470681
21ITK1.37872934
22BMPR1B1.36967094
23VRK11.33222846
24TIE11.31934671
25TEC1.29407916
26PASK1.29141923
27DYRK21.26463726
28FES1.20160357
29MAP3K121.19475131
30GRK61.14246045
31OXSR11.10253424
32SYK1.08874884
33MUSK1.05639733
34IKBKB1.05367799
35PIK3CA1.04290739
36INSRR1.02327254
37MST40.99939424
38NME10.98547034
39PRKCQ0.97952755
40STK390.95825956
41FLT30.95753779
42MAPK130.88844990
43DAPK20.86665118
44GRK70.83275534
45LIMK10.81814026
46IKBKE0.81280373
47BTK0.79956026
48LCK0.79221914
49TNK20.78295048
50ADRBK10.77394207
51PLK40.75987227
52CSF1R0.74501892
53MAP3K110.73311630
54CAMKK20.73217395
55DAPK10.67825054
56LYN0.67764619
57MAP2K70.66381200
58OBSCN0.63739527
59RPS6KA50.62345122
60PIM10.61766438
61PRKCG0.59395069
62MAP3K40.58515565
63MAP2K60.56840350
64PRKACA0.56215246
65DAPK30.55286898
66BMPR20.55181515
67CSNK1G30.54241423
68SCYL20.54098989
69MYLK0.52803357
70CSNK1G10.52792745
71CAMK10.52788988
72PRKCH0.51581843
73MATK0.50766260
74PHKG20.50757658
75PHKG10.50757658
76PIK3CG0.50443524
77CDK80.50390611
78MAPKAPK50.48652987
79CAMKK10.47238156
80PRKCA0.46451911
81CSNK1G20.45701408
82IGF1R0.45500575
83RPS6KA60.45376801
84CSNK2A20.45291874
85MAPKAPK30.43753207
86EIF2AK30.42451211
87AURKA0.41710044
88GRK50.41631160
89PRKCE0.41029272
90RPS6KA40.40942415
91CSNK2A10.37661068
92MAPK150.37247662
93PRKCD0.36241647
94ZAP700.35735498
95NTRK20.35465830
96CAMK2A0.34049087
97TRPM70.33524154
98CDC70.33202630
99CSK0.30909132
100ILK0.30764285

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.71451518
2Oxidative phosphorylation_Homo sapiens_hsa001903.59323306
3Primary immunodeficiency_Homo sapiens_hsa053403.01786404
4Parkinsons disease_Homo sapiens_hsa050122.91924600
5Proteasome_Homo sapiens_hsa030502.81082556
6Asthma_Homo sapiens_hsa053102.46012585
7Allograft rejection_Homo sapiens_hsa053302.37200233
8Autoimmune thyroid disease_Homo sapiens_hsa053202.27110639
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.24454558
10Graft-versus-host disease_Homo sapiens_hsa053322.20851793
11Intestinal immune network for IgA production_Homo sapiens_hsa046722.20338293
12RNA polymerase_Homo sapiens_hsa030202.11700903
13Protein export_Homo sapiens_hsa030602.03981596
14Phototransduction_Homo sapiens_hsa047442.02689659
15Cardiac muscle contraction_Homo sapiens_hsa042601.96321706
16Alzheimers disease_Homo sapiens_hsa050101.93537947
17Huntingtons disease_Homo sapiens_hsa050161.89976894
18Linoleic acid metabolism_Homo sapiens_hsa005911.89002001
19Type I diabetes mellitus_Homo sapiens_hsa049401.87955211
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.71468230
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.66856650
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.63601132
23Antigen processing and presentation_Homo sapiens_hsa046121.57168889
24Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.49205769
25Homologous recombination_Homo sapiens_hsa034401.46965752
26RNA degradation_Homo sapiens_hsa030181.40923227
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.31236200
28Hematopoietic cell lineage_Homo sapiens_hsa046401.27978533
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.23694513
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.22785577
31Caffeine metabolism_Homo sapiens_hsa002321.17139263
32One carbon pool by folate_Homo sapiens_hsa006701.10315757
33Fanconi anemia pathway_Homo sapiens_hsa034601.08754095
34Nicotine addiction_Homo sapiens_hsa050331.06729686
35Nitrogen metabolism_Homo sapiens_hsa009101.06323965
36Peroxisome_Homo sapiens_hsa041461.04104499
37Pyrimidine metabolism_Homo sapiens_hsa002401.03980534
38Rheumatoid arthritis_Homo sapiens_hsa053231.01856019
39Chemical carcinogenesis_Homo sapiens_hsa052041.00357942
40Butanoate metabolism_Homo sapiens_hsa006500.99361423
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.99049271
42Olfactory transduction_Homo sapiens_hsa047400.97461315
43Arachidonic acid metabolism_Homo sapiens_hsa005900.97060329
44Propanoate metabolism_Homo sapiens_hsa006400.97012262
45Tryptophan metabolism_Homo sapiens_hsa003800.96271172
46Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.91667228
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.89160381
48Steroid hormone biosynthesis_Homo sapiens_hsa001400.87986603
49Basal transcription factors_Homo sapiens_hsa030220.87726678
50Ether lipid metabolism_Homo sapiens_hsa005650.86696131
51Retinol metabolism_Homo sapiens_hsa008300.85710919
52Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85706846
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.81819796
54Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.81727376
55Purine metabolism_Homo sapiens_hsa002300.80440087
56Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.80114644
57Nucleotide excision repair_Homo sapiens_hsa034200.79373637
58Maturity onset diabetes of the young_Homo sapiens_hsa049500.77341799
59Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75116453
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73705117
61Mismatch repair_Homo sapiens_hsa034300.72295599
62Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.69001133
63Taste transduction_Homo sapiens_hsa047420.68561442
64Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.67602446
65Regulation of autophagy_Homo sapiens_hsa041400.67564042
66T cell receptor signaling pathway_Homo sapiens_hsa046600.64238044
67Primary bile acid biosynthesis_Homo sapiens_hsa001200.63025828
68DNA replication_Homo sapiens_hsa030300.59430009
69Fat digestion and absorption_Homo sapiens_hsa049750.58506706
70Metabolic pathways_Homo sapiens_hsa011000.57720587
71Base excision repair_Homo sapiens_hsa034100.57491034
72Pentose and glucuronate interconversions_Homo sapiens_hsa000400.56573452
73Morphine addiction_Homo sapiens_hsa050320.55760793
74Viral myocarditis_Homo sapiens_hsa054160.55464065
75Selenocompound metabolism_Homo sapiens_hsa004500.55008491
76Spliceosome_Homo sapiens_hsa030400.54845363
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.53426872
78Collecting duct acid secretion_Homo sapiens_hsa049660.53293897
79RNA transport_Homo sapiens_hsa030130.53238881
80Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.52398667
81NOD-like receptor signaling pathway_Homo sapiens_hsa046210.51312372
82Systemic lupus erythematosus_Homo sapiens_hsa053220.51010674
83Drug metabolism - other enzymes_Homo sapiens_hsa009830.47764517
84Sulfur relay system_Homo sapiens_hsa041220.47445523
85Cysteine and methionine metabolism_Homo sapiens_hsa002700.46309666
86Sulfur metabolism_Homo sapiens_hsa009200.45799310
87Salivary secretion_Homo sapiens_hsa049700.44331793
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.42477593
89SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41831211
90Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38605078
91Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.38188432
92Ovarian steroidogenesis_Homo sapiens_hsa049130.36655975
93NF-kappa B signaling pathway_Homo sapiens_hsa040640.29536664
94Serotonergic synapse_Homo sapiens_hsa047260.29073319
95Circadian entrainment_Homo sapiens_hsa047130.26644040
96beta-Alanine metabolism_Homo sapiens_hsa004100.26517420
97Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.24952526
98Fatty acid degradation_Homo sapiens_hsa000710.23286937
99GABAergic synapse_Homo sapiens_hsa047270.22914376
100Fatty acid elongation_Homo sapiens_hsa000620.22909916

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »