RPS3P2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA double-strand break processing (GO:0000729)6.08654687
2monoubiquitinated protein deubiquitination (GO:0035520)5.75147647
3cell wall macromolecule catabolic process (GO:0016998)5.46644920
4peptidyl-histidine modification (GO:0018202)5.24373556
5retina vasculature morphogenesis in camera-type eye (GO:0061299)5.04330540
6DNA integration (GO:0015074)4.70168787
7heparin metabolic process (GO:0030202)4.63058694
8heparin biosynthetic process (GO:0030210)4.63058694
9kinetochore organization (GO:0051383)4.62430228
10cell wall macromolecule metabolic process (GO:0044036)4.45721177
11retinal cone cell development (GO:0046549)4.37808519
12fucose catabolic process (GO:0019317)4.21942168
13L-fucose metabolic process (GO:0042354)4.21942168
14L-fucose catabolic process (GO:0042355)4.21942168
15oxygen transport (GO:0015671)4.18611056
16meiotic chromosome segregation (GO:0045132)4.13909046
17forebrain neuron differentiation (GO:0021879)4.06887780
18negative regulation of astrocyte differentiation (GO:0048712)3.90727589
19negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.82748382
20negative regulation of translation, ncRNA-mediated (GO:0040033)3.82748382
21regulation of translation, ncRNA-mediated (GO:0045974)3.82748382
22intestinal epithelial cell development (GO:0060576)3.80089712
23inner ear receptor stereocilium organization (GO:0060122)3.74705602
24neural tube formation (GO:0001841)3.73567268
25regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.72715607
26regulation of ER to Golgi vesicle-mediated transport (GO:0060628)3.70837507
27peptidyl-lysine trimethylation (GO:0018023)3.58272517
28modulation of transcription in other organism involved in symbiotic interaction (GO:0052312)3.57156446
29regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.56501453
30epithelial cilium movement (GO:0003351)3.53870767
31regulation of double-strand break repair (GO:2000779)3.53489986
32regulation of double-strand break repair via homologous recombination (GO:0010569)3.51845998
33regulation of non-canonical Wnt signaling pathway (GO:2000050)3.51771515
34cell proliferation in forebrain (GO:0021846)3.50459888
35positive regulation of vasculogenesis (GO:2001214)3.37381307
36estrogen biosynthetic process (GO:0006703)3.32815353
37regulation of development, heterochronic (GO:0040034)3.30482755
38kidney morphogenesis (GO:0060993)3.28640143
39regulation of timing of cell differentiation (GO:0048505)3.27393303
40replication fork processing (GO:0031297)3.25124904
41atrioventricular valve morphogenesis (GO:0003181)3.22374132
42cerebral cortex radially oriented cell migration (GO:0021799)3.20238390
43positive regulation of heart growth (GO:0060421)3.17410209
44positive regulation of oligodendrocyte differentiation (GO:0048714)3.13117695
45regulation of mitotic spindle organization (GO:0060236)3.12236823
46double-strand break repair via homologous recombination (GO:0000724)3.12160054
47negative regulation by host of viral transcription (GO:0043922)3.09094398
48gas transport (GO:0015669)3.07293124
49positive regulation of cardiac muscle tissue growth (GO:0055023)3.06687664
50positive regulation of myoblast differentiation (GO:0045663)3.04964130
51epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.04601994
52protein-cofactor linkage (GO:0018065)3.02746207
53mRNA splice site selection (GO:0006376)3.02715203
54recombinational repair (GO:0000725)3.01385233
55positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.98396650
56positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)2.97800579
57activated T cell proliferation (GO:0050798)2.97488430
58positive regulation of cardiac muscle tissue development (GO:0055025)2.94017390
59negative regulation of JAK-STAT cascade (GO:0046426)2.93762716
60pancreas development (GO:0031016)2.92819291
61regulation of memory T cell differentiation (GO:0043380)2.92338916
62positive regulation of hair cycle (GO:0042635)2.91981132
63positive regulation of hair follicle development (GO:0051798)2.91981132
64bone trabecula formation (GO:0060346)2.90581817
65modulation by host of symbiont transcription (GO:0052472)2.87475040
66modulation by host of viral transcription (GO:0043921)2.87475040
67regulation of telomere maintenance (GO:0032204)2.86785801
68labyrinthine layer development (GO:0060711)2.86755822
69somatic hypermutation of immunoglobulin genes (GO:0016446)2.86615735
70somatic diversification of immune receptors via somatic mutation (GO:0002566)2.86615735
71positive regulation of cardiac muscle cell proliferation (GO:0060045)2.86052552
72positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568)2.86009931
73positive regulation of T-helper 1 type immune response (GO:0002827)2.83693447
74nucleotide transmembrane transport (GO:1901679)2.82040635
75positive regulation of cardiac muscle cell differentiation (GO:2000727)2.80120940
76myoblast differentiation (GO:0045445)2.79102904
77negative T cell selection (GO:0043383)2.75303300
78negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.74976394
79appendage development (GO:0048736)2.73952686
80limb development (GO:0060173)2.73952686
81fucosylation (GO:0036065)2.73739595
82peptidyl-lysine methylation (GO:0018022)2.72908674
83genitalia morphogenesis (GO:0035112)2.72426306
84neurotransmitter catabolic process (GO:0042135)2.70232862
85protein polyglutamylation (GO:0018095)2.65514078
86somatic recombination of immunoglobulin gene segments (GO:0016447)2.64176886
87neuron fate determination (GO:0048664)2.60312522
88cilium morphogenesis (GO:0060271)2.59839676
89regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)2.57334615
90heterochromatin organization (GO:0070828)2.55828370
91regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.53644832
92regulation of NFAT protein import into nucleus (GO:0051532)2.53576254
93regulation of acyl-CoA biosynthetic process (GO:0050812)2.53145023
94regulation of heat generation (GO:0031650)2.52636378
95DNA demethylation (GO:0080111)2.52564369
96lung vasculature development (GO:0060426)2.50992054
97histone H3-K4 trimethylation (GO:0080182)2.50956324
98ionotropic glutamate receptor signaling pathway (GO:0035235)2.49442155
99positive regulation of T cell cytokine production (GO:0002726)2.49098474
100mRNA cleavage (GO:0006379)2.48188440

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.12710810
2CEBPD_23245923_ChIP-Seq_MEFs_Mouse3.07229079
3E2F7_22180533_ChIP-Seq_HELA_Human3.04917595
4IRF1_19129219_ChIP-ChIP_H3396_Human3.01068370
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.89973931
6FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.88606150
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.83516826
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.73475195
9ZNF274_21170338_ChIP-Seq_K562_Hela2.59640598
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.55547077
11MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.52042867
12VDR_22108803_ChIP-Seq_LS180_Human2.42421164
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.36942474
14FLI1_27457419_Chip-Seq_LIVER_Mouse2.36257996
15EWS_26573619_Chip-Seq_HEK293_Human2.30071026
16FUS_26573619_Chip-Seq_HEK293_Human2.18377479
17POU3F2_20337985_ChIP-ChIP_501MEL_Human2.16969671
18PCGF2_27294783_Chip-Seq_NPCs_Mouse2.14709371
19ZFP57_27257070_Chip-Seq_ESCs_Mouse2.03555019
20TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99021497
21POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.99021497
22P300_19829295_ChIP-Seq_ESCs_Human1.98856668
23CTBP2_25329375_ChIP-Seq_LNCAP_Human1.89926115
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84580067
25PCGF2_27294783_Chip-Seq_ESCs_Mouse1.84528919
26AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.74394667
27ER_23166858_ChIP-Seq_MCF-7_Human1.71059670
28EST1_17652178_ChIP-ChIP_JURKAT_Human1.69841272
29POU5F1_16153702_ChIP-ChIP_HESCs_Human1.66520649
30TAF15_26573619_Chip-Seq_HEK293_Human1.65238424
31SMAD3_21741376_ChIP-Seq_EPCs_Human1.63321029
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60969285
33UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.57601363
34TP53_16413492_ChIP-PET_HCT116_Human1.56907501
35SALL1_21062744_ChIP-ChIP_HESCs_Human1.55436235
36NR3C1_21868756_ChIP-Seq_MCF10A_Human1.54260239
37GBX2_23144817_ChIP-Seq_PC3_Human1.52282187
38SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.52255726
39MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.49780520
40RBPJ_22232070_ChIP-Seq_NCS_Mouse1.48429567
41TCF4_23295773_ChIP-Seq_U87_Human1.47754932
42FOXM1_23109430_ChIP-Seq_U2OS_Human1.46774219
43NFE2_27457419_Chip-Seq_LIVER_Mouse1.46743210
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.46612229
45MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.45273837
46HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.42638578
47SUZ12_27294783_Chip-Seq_NPCs_Mouse1.39105159
48PIAS1_25552417_ChIP-Seq_VCAP_Human1.38754869
49E2F1_18555785_Chip-Seq_ESCs_Mouse1.38284414
50EZH2_27294783_Chip-Seq_NPCs_Mouse1.36416608
51SMAD4_21799915_ChIP-Seq_A2780_Human1.35045223
52FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.33491712
53STAT3_23295773_ChIP-Seq_U87_Human1.33136859
54CBX2_27304074_Chip-Seq_ESCs_Mouse1.30974613
55BCAT_22108803_ChIP-Seq_LS180_Human1.30712014
56GABP_17652178_ChIP-ChIP_JURKAT_Human1.30037266
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.29966103
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.29727506
59EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.28517272
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.27447694
61RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26522281
62SUZ12_18555785_Chip-Seq_ESCs_Mouse1.24857983
63P53_22387025_ChIP-Seq_ESCs_Mouse1.23699824
64CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.23608742
65CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.22526004
66CTBP1_25329375_ChIP-Seq_LNCAP_Human1.21194979
67TP53_22573176_ChIP-Seq_HFKS_Human1.20299304
68ELK1_19687146_ChIP-ChIP_HELA_Human1.19834245
69SCL_19346495_ChIP-Seq_HPC-7_Human1.17462661
70CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.17380250
71FLI1_21867929_ChIP-Seq_TH2_Mouse1.17166287
72KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.16043631
73STAT3_18555785_Chip-Seq_ESCs_Mouse1.15529396
74KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.14935193
75NOTCH1_21737748_ChIP-Seq_TLL_Human1.14245955
76TBX3_20139965_ChIP-Seq_ESCs_Mouse1.13010843
77CMYC_18555785_Chip-Seq_ESCs_Mouse1.12755049
78AR_25329375_ChIP-Seq_VCAP_Human1.11054738
79SALL4_22934838_ChIP-ChIP_CD34+_Human1.11037030
80TBX3_20139965_ChIP-Seq_MESCs_Mouse1.11025010
81SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.09102729
82EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.08964646
83NMYC_18555785_Chip-Seq_ESCs_Mouse1.07352636
84AR_21909140_ChIP-Seq_LNCAP_Human1.06294746
85IGF1R_20145208_ChIP-Seq_DFB_Human1.05867988
86CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.05377167
87OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.05006788
88OCT4_18555785_Chip-Seq_ESCs_Mouse1.04754226
89OCT4_21477851_ChIP-Seq_ESCs_Mouse1.04571343
90FOXM1_26456572_ChIP-Seq_MCF-7_Human1.04533116
91FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.04518075
92SMAD_19615063_ChIP-ChIP_OVARY_Human1.03059677
93SOX2_19829295_ChIP-Seq_ESCs_Human1.02653232
94NANOG_19829295_ChIP-Seq_ESCs_Human1.02653232
95TCF4_22108803_ChIP-Seq_LS180_Human1.01952276
96SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.01558918
97RXR_22108803_ChIP-Seq_LS180_Human1.00207826
98ESRRB_18555785_Chip-Seq_ESCs_Mouse0.99966218
99GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.99410252
100STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.98635526

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication5.11363385
2MP0000569_abnormal_digit_pigmentation4.08963866
3MP0003283_abnormal_digestive_organ3.56297844
4MP0004043_abnormal_pH_regulation3.15529445
5MP0003890_abnormal_embryonic-extraembry3.11401126
6MP0008875_abnormal_xenobiotic_pharmacok2.79161075
7MP0008058_abnormal_DNA_repair2.62715017
8MP0003878_abnormal_ear_physiology2.44991502
9MP0005377_hearing/vestibular/ear_phenot2.44991502
10MP0010094_abnormal_chromosome_stability2.18399157
11MP0006292_abnormal_olfactory_placode2.17759797
12MP0010030_abnormal_orbit_morphology2.13483865
13MP0009697_abnormal_copulation2.11711990
14MP0008961_abnormal_basal_metabolism2.06843860
15MP0002751_abnormal_autonomic_nervous1.95540760
16MP0005174_abnormal_tail_pigmentation1.80193814
17MP0002138_abnormal_hepatobiliary_system1.73149545
18MP0001851_eye_inflammation1.69929916
19MP0002282_abnormal_trachea_morphology1.68621437
20MP0010307_abnormal_tumor_latency1.67717474
21MP0008789_abnormal_olfactory_epithelium1.63558252
22MP0003763_abnormal_thymus_physiology1.59016804
23MP0008932_abnormal_embryonic_tissue1.53147111
24MP0002396_abnormal_hematopoietic_system1.45538489
25MP0005499_abnormal_olfactory_system1.45003461
26MP0005394_taste/olfaction_phenotype1.45003461
27MP0003937_abnormal_limbs/digits/tail_de1.33455955
28MP0001879_abnormal_lymphatic_vessel1.32456572
29MP0009333_abnormal_splenocyte_physiolog1.32398859
30MP0010386_abnormal_urinary_bladder1.32261993
31MP0003119_abnormal_digestive_system1.28802084
32MP0005365_abnormal_bile_salt1.27780567
33MP0004085_abnormal_heartbeat1.26493284
34MP0008877_abnormal_DNA_methylation1.24487919
35MP0005551_abnormal_eye_electrophysiolog1.23855194
36MP0002095_abnormal_skin_pigmentation1.21012913
37MP0005248_abnormal_Harderian_gland1.20795408
38MP0001873_stomach_inflammation1.20440375
39MP0005379_endocrine/exocrine_gland_phen1.19623753
40MP0002653_abnormal_ependyma_morphology1.19449874
41MP0009703_decreased_birth_body1.16783426
42MP0003121_genomic_imprinting1.13192374
43MP0003718_maternal_effect1.12688904
44MP0003077_abnormal_cell_cycle1.10260855
45MP0005409_darkened_coat_color1.10222979
46MP0000427_abnormal_hair_cycle1.09913833
47MP0001958_emphysema1.07145535
48MP0006072_abnormal_retinal_apoptosis1.06429277
49MP0004885_abnormal_endolymph1.00967779
50MP0000778_abnormal_nervous_system1.00800818
51MP0001697_abnormal_embryo_size0.98722620
52MP0004142_abnormal_muscle_tone0.98489935
53MP0005253_abnormal_eye_physiology0.98010721
54MP0002184_abnormal_innervation0.95758433
55MP0004381_abnormal_hair_follicle0.94569409
56MP0001486_abnormal_startle_reflex0.94148720
57MP0002928_abnormal_bile_duct0.91576913
58MP0004197_abnormal_fetal_growth/weight/0.91201494
59MP0001485_abnormal_pinna_reflex0.88969098
60MP0002084_abnormal_developmental_patter0.87912488
61MP0003137_abnormal_impulse_conducting0.87138781
62MP0002067_abnormal_sensory_capabilities0.85657123
63MP0000647_abnormal_sebaceous_gland0.82012451
64MP0003632_abnormal_nervous_system0.81506524
65MP0001929_abnormal_gametogenesis0.80228962
66MP0004957_abnormal_blastocyst_morpholog0.79717422
67MP0002090_abnormal_vision0.78806375
68MP0000015_abnormal_ear_pigmentation0.78664658
69MP0002166_altered_tumor_susceptibility0.78132195
70MP0005448_abnormal_energy_balance0.78055419
71MP0000653_abnormal_sex_gland0.77250731
72MP0002210_abnormal_sex_determination0.76241498
73MP0002109_abnormal_limb_morphology0.75656211
74MP0005195_abnormal_posterior_eye0.73926904
75MP0008770_decreased_survivor_rate0.73904212
76MP0004742_abnormal_vestibular_system0.72640734
77MP0008872_abnormal_physiological_respon0.72417374
78MP0003936_abnormal_reproductive_system0.72346166
79MP0006035_abnormal_mitochondrial_morpho0.71674887
80MP0003123_paternal_imprinting0.71310802
81MP0003111_abnormal_nucleus_morphology0.70860609
82MP0003861_abnormal_nervous_system0.70663428
83MP0005410_abnormal_fertilization0.70294947
84MP0000026_abnormal_inner_ear0.68984742
85MP0005646_abnormal_pituitary_gland0.68310963
86MP0001119_abnormal_female_reproductive0.66459345
87MP0002088_abnormal_embryonic_growth/wei0.65864069
88MP0003693_abnormal_embryo_hatching0.64725038
89MP0003984_embryonic_growth_retardation0.64644756
90MP0005083_abnormal_biliary_tract0.64078449
91MP0003183_abnormal_peptide_metabolism0.62774824
92MP0002752_abnormal_somatic_nervous0.61686403
93MP0000639_abnormal_adrenal_gland0.59406251
94MP0002111_abnormal_tail_morphology0.59200702
95MP0001800_abnormal_humoral_immune0.58278012
96MP0002085_abnormal_embryonic_tissue0.58106200
97MP0001286_abnormal_eye_development0.58094916
98MP0001145_abnormal_male_reproductive0.57667498
99MP0000350_abnormal_cell_proliferation0.57462342
100MP0003136_yellow_coat_color0.57071603

Predicted human phenotypes

RankGene SetZ-score
1Malnutrition (HP:0004395)4.89823782
2Oligodactyly (hands) (HP:0001180)3.84622206
3Progressive inability to walk (HP:0002505)3.69012144
4Steatorrhea (HP:0002570)3.62383000
5Absent rod-and cone-mediated responses on ERG (HP:0007688)3.58410169
6Pancreatic cysts (HP:0001737)3.56611299
7Molar tooth sign on MRI (HP:0002419)3.53859445
8Abnormality of midbrain morphology (HP:0002418)3.53859445
9Rhinitis (HP:0012384)3.48371817
10Aplasia/Hypoplasia of the spleen (HP:0010451)3.41207205
11Dyschromatopsia (HP:0007641)3.37985463
12Intestinal atresia (HP:0011100)3.37200666
13Abnormal biliary tract physiology (HP:0012439)3.26082117
14Bile duct proliferation (HP:0001408)3.26082117
15Duplicated collecting system (HP:0000081)3.25805969
16Clubbing of toes (HP:0100760)3.22500444
17Depressed nasal tip (HP:0000437)3.19955568
18Chromsome breakage (HP:0040012)3.17408993
19Nephroblastoma (Wilms tumor) (HP:0002667)3.14859160
20Pancreatic fibrosis (HP:0100732)3.03975665
21Asplenia (HP:0001746)3.02041462
22Tubular atrophy (HP:0000092)3.01613248
23Diastasis recti (HP:0001540)2.94381834
24Chromosomal breakage induced by crosslinking agents (HP:0003221)2.93598030
25Embryonal renal neoplasm (HP:0011794)2.93271621
26Aplasia/Hypoplasia of the uvula (HP:0010293)2.92928099
27Nephronophthisis (HP:0000090)2.89767218
28Abnormality of the ileum (HP:0001549)2.85660553
29Abnormality of the renal collecting system (HP:0004742)2.80132245
30Abnormality of the renal medulla (HP:0100957)2.73896607
31Fat malabsorption (HP:0002630)2.66871322
32True hermaphroditism (HP:0010459)2.65484073
33Oligodactyly (HP:0012165)2.54580144
34Vitreoretinal degeneration (HP:0000655)2.54514476
35Abnormal hemoglobin (HP:0011902)2.54286792
36Abnormality of chromosome stability (HP:0003220)2.52590027
37Meckel diverticulum (HP:0002245)2.50696475
38Hepatocellular necrosis (HP:0001404)2.47024748
39Aplasia/Hypoplasia involving the musculature (HP:0001460)2.46833418
40Tubulointerstitial nephritis (HP:0001970)2.43408134
41Abnormality of the renal cortex (HP:0011035)2.43404009
42Atonic seizures (HP:0010819)2.32368059
43Increased hepatocellular lipid droplets (HP:0006565)2.26421743
44Respiratory difficulties (HP:0002880)2.24986849
45Abnormal rod and cone electroretinograms (HP:0008323)2.24932017
46Hypoplasia of the pons (HP:0012110)2.21841326
47Autoamputation (HP:0001218)2.21200135
48Duodenal stenosis (HP:0100867)2.20108895
49Small intestinal stenosis (HP:0012848)2.20108895
50Cystic liver disease (HP:0006706)2.17176768
51Abnormality of alanine metabolism (HP:0010916)2.16974991
52Hyperalaninemia (HP:0003348)2.16974991
53Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.16974991
54Attenuation of retinal blood vessels (HP:0007843)2.16570329
55Volvulus (HP:0002580)2.15084487
56Abnormality of the preputium (HP:0100587)2.13505009
57Large for gestational age (HP:0001520)2.13193317
58Abnormality of the pons (HP:0007361)2.09824084
59Long foot (HP:0001833)2.09806647
60Medulloblastoma (HP:0002885)2.09677235
61Abnormality of the fingertips (HP:0001211)2.09624070
62Abnormality of the duodenum (HP:0002246)2.07691381
63Inability to walk (HP:0002540)2.06958988
64Ectopic kidney (HP:0000086)2.06210339
65Supernumerary spleens (HP:0009799)2.02979278
66Tubulointerstitial abnormality (HP:0001969)2.02100565
67Ependymoma (HP:0002888)2.01814646
68Abnormal drinking behavior (HP:0030082)2.00232556
69Polydipsia (HP:0001959)2.00232556
70Short 4th metacarpal (HP:0010044)1.93784840
71Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.93784840
72Abnormality of the nasal septum (HP:0000419)1.93416967
73Split foot (HP:0001839)1.92371894
74Fibular aplasia (HP:0002990)1.91547640
75Gastrointestinal atresia (HP:0002589)1.90922229
76Exertional dyspnea (HP:0002875)1.90683615
77Increased number of teeth (HP:0011069)1.87481435
78Abolished electroretinogram (ERG) (HP:0000550)1.87043871
79Biliary tract neoplasm (HP:0100574)1.87024480
80Birth length less than 3rd percentile (HP:0003561)1.85058800
81Mitochondrial inheritance (HP:0001427)1.83607402
82Lipid accumulation in hepatocytes (HP:0006561)1.83231755
832-3 toe syndactyly (HP:0004691)1.82072205
84Acute necrotizing encephalopathy (HP:0006965)1.81144842
85Progressive macrocephaly (HP:0004481)1.80999588
86Widely spaced teeth (HP:0000687)1.80725781
87Spinal cord lesions (HP:0100561)1.79889479
88Syringomyelia (HP:0003396)1.79889479
89Tented upper lip vermilion (HP:0010804)1.78547972
90Abnormality of the carotid arteries (HP:0005344)1.78440097
91Narrow forehead (HP:0000341)1.77302049
92Arthropathy (HP:0003040)1.77149229
93Abnormality of the 4th metacarpal (HP:0010012)1.76201381
94Polyuria (HP:0000103)1.75441772
95Increased CSF lactate (HP:0002490)1.73518583
96Enlarged kidneys (HP:0000105)1.71866647
97Bifid tongue (HP:0010297)1.71754165
98Rhabdomyosarcoma (HP:0002859)1.69612589
99Abnormality of the aortic arch (HP:0012303)1.68687582
100Cranial hyperostosis (HP:0004437)1.68414911

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ERBB44.73203582
2CCNB14.52640604
3MAP3K43.21847746
4ACVR1B2.90844448
5MAP3K102.90358141
6WNK42.88805207
7PKN22.77205969
8FRK2.47195860
9MAP2K72.23748760
10NTRK32.13489064
11TNIK2.08017885
12TSSK62.07261395
13TXK2.03868150
14BMPR1B2.01882376
15CDK31.92682776
16PDK21.81673817
17CDC71.71417100
18MAPK71.69997073
19STK391.68626703
20TGFBR11.66283514
21IRAK11.61621653
22NUAK11.58559718
23FLT31.55613733
24MAP2K41.50697239
25MKNK21.49402310
26PLK41.45249250
27MAP3K121.41888868
28INSRR1.38981612
29RPS6KA41.35918012
30MAP4K21.31749616
31WEE11.30498082
32NLK1.27616071
33PIK3CA1.13649505
34WNK11.11661856
35TLK11.10498986
36ZAK1.10269422
37MST41.05134040
38BRSK21.03540481
39MKNK11.02709527
40PAK30.98349891
41MAPKAPK50.89442648
42MAP3K60.84685365
43PHKG20.84316431
44PHKG10.84316431
45DYRK30.79472977
46PINK10.77861320
47PNCK0.76158001
48BLK0.75675972
49MAPK130.75289526
50MAP2K60.74171966
51IRAK20.74158798
52GRK10.73394066
53RPS6KA50.72237132
54JAK30.71619243
55IRAK40.71479427
56MELK0.70032479
57SRPK10.69738937
58MAP3K50.64864301
59FGFR20.64042429
60EPHA40.61045353
61PDGFRB0.60481583
62ERBB30.60291053
63OXSR10.59182557
64FGFR10.57950095
65CDK120.57036450
66ADRBK20.55320176
67EPHA30.55173523
68ITK0.52083618
69MAP3K130.51513965
70ERBB20.50844066
71STK160.50321210
72MAPKAPK30.49941764
73PLK30.49776173
74MAP3K90.49539883
75ATR0.48464673
76AKT30.45228691
77RAF10.43983698
78GRK50.41734634
79CDK80.41527663
80CHUK0.41113388
81ATM0.41095470
82IKBKE0.39307479
83YES10.37753652
84PRKCE0.37179017
85PLK10.36126160
86SGK30.34843657
87MARK30.34188413
88TYK20.34141344
89PRKD30.33904250
90STK38L0.33550210
91VRK10.33357327
92PRKCG0.33029875
93CDK70.32764699
94STK30.30793373
95BRSK10.30315485
96TAF10.29735802
97PRKCZ0.28963756
98TAOK10.27587835
99TEC0.26669579
100IKBKB0.25407524

Predicted pathways (KEGG)

RankGene SetZ-score
1Fanconi anemia pathway_Homo sapiens_hsa034603.32621471
2Homologous recombination_Homo sapiens_hsa034403.28347316
3Systemic lupus erythematosus_Homo sapiens_hsa053223.17768177
4Primary bile acid biosynthesis_Homo sapiens_hsa001202.53117259
5Base excision repair_Homo sapiens_hsa034102.25971732
6Autoimmune thyroid disease_Homo sapiens_hsa053202.15659956
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.06039219
8Mismatch repair_Homo sapiens_hsa034302.02708800
9Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.92721344
10Graft-versus-host disease_Homo sapiens_hsa053321.89843492
11Allograft rejection_Homo sapiens_hsa053301.80391906
12Nitrogen metabolism_Homo sapiens_hsa009101.76195537
13Alcoholism_Homo sapiens_hsa050341.72426441
14Basal transcription factors_Homo sapiens_hsa030221.69093736
15DNA replication_Homo sapiens_hsa030301.64011109
16Steroid hormone biosynthesis_Homo sapiens_hsa001401.59174849
17Proteasome_Homo sapiens_hsa030501.57803809
18Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.57244708
19Taste transduction_Homo sapiens_hsa047421.49787624
20Nucleotide excision repair_Homo sapiens_hsa034201.49238041
21Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.47068765
22Type I diabetes mellitus_Homo sapiens_hsa049401.43412299
23p53 signaling pathway_Homo sapiens_hsa041151.30324254
24Parkinsons disease_Homo sapiens_hsa050121.27965261
25Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.27498674
26Non-homologous end-joining_Homo sapiens_hsa034501.27318896
27Malaria_Homo sapiens_hsa051441.24838940
28Protein export_Homo sapiens_hsa030601.24399775
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.20975269
30Linoleic acid metabolism_Homo sapiens_hsa005911.16805220
31Dorso-ventral axis formation_Homo sapiens_hsa043201.15825770
32Oxidative phosphorylation_Homo sapiens_hsa001901.14301878
33Notch signaling pathway_Homo sapiens_hsa043301.12334102
34Viral carcinogenesis_Homo sapiens_hsa052031.11684559
35Pentose and glucuronate interconversions_Homo sapiens_hsa000401.11167692
36Olfactory transduction_Homo sapiens_hsa047401.11105610
37Spliceosome_Homo sapiens_hsa030401.06148600
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.06135319
39Transcriptional misregulation in cancer_Homo sapiens_hsa052021.05564876
40Cardiac muscle contraction_Homo sapiens_hsa042601.02932777
41Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.00715751
42Lysine degradation_Homo sapiens_hsa003100.98463594
43TGF-beta signaling pathway_Homo sapiens_hsa043500.98205179
44Hedgehog signaling pathway_Homo sapiens_hsa043400.96850390
45Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95996387
46Other glycan degradation_Homo sapiens_hsa005110.95936604
47Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.95518145
48Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.92384002
49African trypanosomiasis_Homo sapiens_hsa051430.88541992
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.88057598
51alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.87677821
52Primary immunodeficiency_Homo sapiens_hsa053400.87272024
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.86934544
54Huntingtons disease_Homo sapiens_hsa050160.85329707
55RNA transport_Homo sapiens_hsa030130.81044180
56Nicotine addiction_Homo sapiens_hsa050330.79268744
57RNA polymerase_Homo sapiens_hsa030200.78930701
58Ovarian steroidogenesis_Homo sapiens_hsa049130.76999000
59Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.76716952
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.76240585
61mRNA surveillance pathway_Homo sapiens_hsa030150.75014903
62Chemical carcinogenesis_Homo sapiens_hsa052040.73825262
63Pyruvate metabolism_Homo sapiens_hsa006200.72988629
64Jak-STAT signaling pathway_Homo sapiens_hsa046300.72323440
65RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.72284601
66NOD-like receptor signaling pathway_Homo sapiens_hsa046210.71549731
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70344557
68RNA degradation_Homo sapiens_hsa030180.66056269
69Legionellosis_Homo sapiens_hsa051340.64771400
70T cell receptor signaling pathway_Homo sapiens_hsa046600.64118622
71Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63328345
72FoxO signaling pathway_Homo sapiens_hsa040680.61836714
73Wnt signaling pathway_Homo sapiens_hsa043100.57767897
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.56994525
75Propanoate metabolism_Homo sapiens_hsa006400.56524826
76Retinol metabolism_Homo sapiens_hsa008300.53567308
77Phototransduction_Homo sapiens_hsa047440.53030325
78Measles_Homo sapiens_hsa051620.52668488
79Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52438667
80Circadian rhythm_Homo sapiens_hsa047100.52309091
81Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.51856691
82Alzheimers disease_Homo sapiens_hsa050100.48582859
83ErbB signaling pathway_Homo sapiens_hsa040120.48528517
84Selenocompound metabolism_Homo sapiens_hsa004500.46368634
85MicroRNAs in cancer_Homo sapiens_hsa052060.45749044
86Butanoate metabolism_Homo sapiens_hsa006500.45386749
87Basal cell carcinoma_Homo sapiens_hsa052170.44929459
88Cell cycle_Homo sapiens_hsa041100.44739119
89Type II diabetes mellitus_Homo sapiens_hsa049300.43726431
90Pyrimidine metabolism_Homo sapiens_hsa002400.43537374
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.42873537
92Purine metabolism_Homo sapiens_hsa002300.42748579
93TNF signaling pathway_Homo sapiens_hsa046680.41555514
94Starch and sucrose metabolism_Homo sapiens_hsa005000.40189632
95Fatty acid biosynthesis_Homo sapiens_hsa000610.38862545
96Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.37750395
97Apoptosis_Homo sapiens_hsa042100.37314986
98Renin secretion_Homo sapiens_hsa049240.36854273
99Long-term depression_Homo sapiens_hsa047300.34538915
100Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.32594715

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »