

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.60258405 |
| 2 | DNA deamination (GO:0045006) | 5.31949162 |
| 3 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 5.07189614 |
| 4 | regulation of immunoglobulin secretion (GO:0051023) | 4.86842569 |
| 5 | regulation of chronic inflammatory response (GO:0002676) | 4.63071013 |
| 6 | rRNA modification (GO:0000154) | 4.51125200 |
| 7 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.48708201 |
| 8 | cellular response to exogenous dsRNA (GO:0071360) | 4.42880979 |
| 9 | proteasome assembly (GO:0043248) | 4.16597535 |
| 10 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.15487014 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 4.06388610 |
| 12 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.06388610 |
| 13 | positive regulation of DNA recombination (GO:0045911) | 4.03540569 |
| 14 | ribosomal large subunit biogenesis (GO:0042273) | 4.03532438 |
| 15 | positive regulation of defense response to virus by host (GO:0002230) | 4.03018693 |
| 16 | positive regulation of isotype switching (GO:0045830) | 3.91911549 |
| 17 | ribosomal small subunit assembly (GO:0000028) | 3.87477287 |
| 18 | sleep (GO:0030431) | 3.80595495 |
| 19 | chaperone-mediated protein transport (GO:0072321) | 3.73997120 |
| 20 | pseudouridine synthesis (GO:0001522) | 3.72948229 |
| 21 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.71233721 |
| 22 | rRNA methylation (GO:0031167) | 3.64834819 |
| 23 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.57109352 |
| 24 | maturation of 5.8S rRNA (GO:0000460) | 3.56172067 |
| 25 | GTP biosynthetic process (GO:0006183) | 3.48305954 |
| 26 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.45156547 |
| 27 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.41241780 |
| 28 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.39952579 |
| 29 | isotype switching (GO:0045190) | 3.39952579 |
| 30 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.39952579 |
| 31 | behavioral response to nicotine (GO:0035095) | 3.38117611 |
| 32 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.38082993 |
| 33 | termination of RNA polymerase III transcription (GO:0006386) | 3.38082993 |
| 34 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.26947671 |
| 35 | rRNA metabolic process (GO:0016072) | 3.25258578 |
| 36 | rRNA processing (GO:0006364) | 3.21498250 |
| 37 | regulation of regulatory T cell differentiation (GO:0045589) | 3.18678386 |
| 38 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.18447253 |
| 39 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.18447253 |
| 40 | cellular response to dsRNA (GO:0071359) | 3.18144908 |
| 41 | termination of RNA polymerase I transcription (GO:0006363) | 3.17131984 |
| 42 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.15953346 |
| 43 | negative regulation of telomere maintenance (GO:0032205) | 3.13583334 |
| 44 | positive regulation of prostaglandin secretion (GO:0032308) | 3.12247483 |
| 45 | cytidine metabolic process (GO:0046087) | 3.10628749 |
| 46 | cytidine catabolic process (GO:0006216) | 3.10628749 |
| 47 | cytidine deamination (GO:0009972) | 3.10628749 |
| 48 | piRNA metabolic process (GO:0034587) | 3.06833452 |
| 49 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.06132269 |
| 50 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.04689905 |
| 51 | positive regulation of B cell mediated immunity (GO:0002714) | 3.04689905 |
| 52 | UTP biosynthetic process (GO:0006228) | 3.04268571 |
| 53 | tRNA processing (GO:0008033) | 3.02662796 |
| 54 | translation (GO:0006412) | 3.02177879 |
| 55 | rRNA catabolic process (GO:0016075) | 3.01837017 |
| 56 | cellular response to interferon-beta (GO:0035458) | 2.99384071 |
| 57 | regulation of defense response to virus by host (GO:0050691) | 2.94288554 |
| 58 | mannosylation (GO:0097502) | 2.92772793 |
| 59 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.87711891 |
| 60 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.87711891 |
| 61 | negative regulation of B cell apoptotic process (GO:0002903) | 2.87623739 |
| 62 | UTP metabolic process (GO:0046051) | 2.87336202 |
| 63 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.86030167 |
| 64 | nucleotide transmembrane transport (GO:1901679) | 2.85818776 |
| 65 | positive regulation of activated T cell proliferation (GO:0042104) | 2.79469896 |
| 66 | ribosome assembly (GO:0042255) | 2.78161188 |
| 67 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.77908179 |
| 68 | ribosome biogenesis (GO:0042254) | 2.77882804 |
| 69 | tRNA metabolic process (GO:0006399) | 2.77785249 |
| 70 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.76070755 |
| 71 | tRNA modification (GO:0006400) | 2.75176433 |
| 72 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.74771586 |
| 73 | translational elongation (GO:0006414) | 2.72531287 |
| 74 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.71227081 |
| 75 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.71227081 |
| 76 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.71227081 |
| 77 | viral transcription (GO:0019083) | 2.70987107 |
| 78 | positive regulation of interleukin-17 production (GO:0032740) | 2.69439376 |
| 79 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.69321776 |
| 80 | ncRNA metabolic process (GO:0034660) | 2.69114602 |
| 81 | ncRNA processing (GO:0034470) | 2.68999377 |
| 82 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.68859044 |
| 83 | somatic diversification of immunoglobulins (GO:0016445) | 2.68579543 |
| 84 | transcription from RNA polymerase I promoter (GO:0006360) | 2.68480679 |
| 85 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.66357132 |
| 86 | CTP metabolic process (GO:0046036) | 2.65582436 |
| 87 | CTP biosynthetic process (GO:0006241) | 2.65582436 |
| 88 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.65554349 |
| 89 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.65554349 |
| 90 | translational termination (GO:0006415) | 2.64937391 |
| 91 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.64471014 |
| 92 | cotranslational protein targeting to membrane (GO:0006613) | 2.64019514 |
| 93 | protein targeting to ER (GO:0045047) | 2.63457315 |
| 94 | GMP metabolic process (GO:0046037) | 2.63138756 |
| 95 | cellular component biogenesis (GO:0044085) | 2.62834648 |
| 96 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.60540660 |
| 97 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 2.59190407 |
| 98 | regulation of growth of symbiont in host (GO:0044126) | 2.59190407 |
| 99 | negative regulation of growth of symbiont in host (GO:0044130) | 2.59190407 |
| 100 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 2.59190407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.70898949 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.59932398 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.43886348 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.18158331 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.14897789 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.08147644 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.05043677 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.83587694 |
| 9 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.82474270 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.77797727 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.69622463 |
| 12 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.46496701 |
| 13 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.44000484 |
| 14 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.35658228 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.31082595 |
| 16 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.31017606 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.24632870 |
| 18 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.22889903 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.16482310 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.11233176 |
| 21 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.04973043 |
| 22 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.04023577 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.94150854 |
| 24 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.93350599 |
| 25 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.91329303 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.88962750 |
| 27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.81747631 |
| 28 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.81600277 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.73677578 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.66944327 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.66592781 |
| 32 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.64356794 |
| 33 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.60681208 |
| 34 | GATA3_26560356_Chip-Seq_TH2_Human | 1.57526984 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.56354036 |
| 36 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.51716503 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.51113991 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.50562565 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.49629246 |
| 40 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.43898563 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.43138263 |
| 42 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.43138263 |
| 43 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.39857934 |
| 44 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.35702117 |
| 45 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.33634457 |
| 46 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.33053170 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31242569 |
| 48 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.29625324 |
| 49 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.29273174 |
| 50 | AR_20517297_ChIP-Seq_VCAP_Human | 1.28898902 |
| 51 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.27129043 |
| 52 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.26462500 |
| 53 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21153364 |
| 54 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.21077859 |
| 55 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.20451878 |
| 56 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.19922425 |
| 57 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.17111144 |
| 58 | NCOR_22424771_ChIP-Seq_293T_Human | 1.16781619 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.16516360 |
| 60 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.15616452 |
| 61 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.12561105 |
| 62 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.12530050 |
| 63 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.12449720 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11129817 |
| 65 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.11110988 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11066380 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11066380 |
| 68 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.10030383 |
| 69 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.08905993 |
| 70 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.08452159 |
| 71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.06935510 |
| 72 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.06618867 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05133866 |
| 74 | GATA3_26560356_Chip-Seq_TH1_Human | 1.04809548 |
| 75 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.01341587 |
| 76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01136607 |
| 77 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.00973390 |
| 78 | MYB_26560356_Chip-Seq_TH2_Human | 1.00168219 |
| 79 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99389800 |
| 80 | ERA_21632823_ChIP-Seq_H3396_Human | 0.98895207 |
| 81 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.98377692 |
| 82 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.98248302 |
| 83 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.97392681 |
| 84 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.96294191 |
| 85 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.95484369 |
| 86 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.95336647 |
| 87 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.94622538 |
| 88 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.94423541 |
| 89 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93468036 |
| 90 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.92660707 |
| 91 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.91893433 |
| 92 | P300_19829295_ChIP-Seq_ESCs_Human | 0.91299071 |
| 93 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90827720 |
| 94 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.90614667 |
| 95 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.90614667 |
| 96 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.90529654 |
| 97 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.87907236 |
| 98 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.87607201 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.87388761 |
| 100 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.86857170 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 3.79179734 |
| 2 | MP0000685_abnormal_immune_system | 3.64914074 |
| 3 | MP0005671_abnormal_response_to | 3.36339048 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.35400683 |
| 5 | MP0002254_reproductive_system_inflammat | 2.82564374 |
| 6 | MP0002102_abnormal_ear_morphology | 2.68142157 |
| 7 | MP0001348_abnormal_lacrimal_gland | 2.64573912 |
| 8 | MP0002876_abnormal_thyroid_physiology | 2.51936366 |
| 9 | MP0001873_stomach_inflammation | 2.29950142 |
| 10 | MP0008872_abnormal_physiological_respon | 2.17660439 |
| 11 | MP0008058_abnormal_DNA_repair | 2.16828089 |
| 12 | MP0002148_abnormal_hypersensitivity_rea | 2.13340228 |
| 13 | MP0002736_abnormal_nociception_after | 1.99280467 |
| 14 | MP0003195_calcinosis | 1.96765290 |
| 15 | MP0005646_abnormal_pituitary_gland | 1.95029468 |
| 16 | MP0001968_abnormal_touch/_nociception | 1.92650877 |
| 17 | MP0009785_altered_susceptibility_to | 1.85902236 |
| 18 | MP0000604_amyloidosis | 1.85512144 |
| 19 | MP0003763_abnormal_thymus_physiology | 1.81712875 |
| 20 | MP0003786_premature_aging | 1.80235059 |
| 21 | MP0002138_abnormal_hepatobiliary_system | 1.73027548 |
| 22 | MP0008875_abnormal_xenobiotic_pharmacok | 1.72401931 |
| 23 | MP0002166_altered_tumor_susceptibility | 1.71802853 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.69170625 |
| 25 | MP0004885_abnormal_endolymph | 1.64552656 |
| 26 | MP0003646_muscle_fatigue | 1.64476889 |
| 27 | MP0002006_tumorigenesis | 1.63252273 |
| 28 | MP0001800_abnormal_humoral_immune | 1.61665109 |
| 29 | MP0006292_abnormal_olfactory_placode | 1.59994794 |
| 30 | MP0006072_abnormal_retinal_apoptosis | 1.57616014 |
| 31 | MP0005387_immune_system_phenotype | 1.54993601 |
| 32 | MP0001790_abnormal_immune_system | 1.54993601 |
| 33 | MP0001501_abnormal_sleep_pattern | 1.53688595 |
| 34 | MP0005000_abnormal_immune_tolerance | 1.51518920 |
| 35 | MP0000427_abnormal_hair_cycle | 1.49399005 |
| 36 | MP0005551_abnormal_eye_electrophysiolog | 1.48609676 |
| 37 | MP0009764_decreased_sensitivity_to | 1.47482101 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.45282329 |
| 39 | MP0004147_increased_porphyrin_level | 1.44770972 |
| 40 | MP0005310_abnormal_salivary_gland | 1.43115421 |
| 41 | MP0009379_abnormal_foot_pigmentation | 1.37404377 |
| 42 | MP0003693_abnormal_embryo_hatching | 1.34521142 |
| 43 | MP0001986_abnormal_taste_sensitivity | 1.30408171 |
| 44 | MP0008995_early_reproductive_senescence | 1.29222462 |
| 45 | MP0004142_abnormal_muscle_tone | 1.27837652 |
| 46 | MP0005389_reproductive_system_phenotype | 1.27211990 |
| 47 | MP0000465_gastrointestinal_hemorrhage | 1.26804304 |
| 48 | MP0010094_abnormal_chromosome_stability | 1.26596130 |
| 49 | MP0002723_abnormal_immune_serum | 1.25817269 |
| 50 | MP0001919_abnormal_reproductive_system | 1.25579468 |
| 51 | MP0003806_abnormal_nucleotide_metabolis | 1.21467549 |
| 52 | MP0000372_irregular_coat_pigmentation | 1.20867145 |
| 53 | MP0002420_abnormal_adaptive_immunity | 1.20855751 |
| 54 | MP0001819_abnormal_immune_cell | 1.20708364 |
| 55 | MP0005025_abnormal_response_to | 1.19018326 |
| 56 | MP0003866_abnormal_defecation | 1.16704062 |
| 57 | MP0002452_abnormal_antigen_presenting | 1.16582310 |
| 58 | MP0003436_decreased_susceptibility_to | 1.13781407 |
| 59 | MP0008789_abnormal_olfactory_epithelium | 1.13453764 |
| 60 | MP0002160_abnormal_reproductive_system | 1.11736111 |
| 61 | MP0005084_abnormal_gallbladder_morpholo | 1.05360439 |
| 62 | MP0001845_abnormal_inflammatory_respons | 1.05050067 |
| 63 | MP0010155_abnormal_intestine_physiology | 1.04800275 |
| 64 | MP0003718_maternal_effect | 1.02987477 |
| 65 | MP0009333_abnormal_splenocyte_physiolog | 1.02905539 |
| 66 | MP0005167_abnormal_blood-brain_barrier | 1.02417755 |
| 67 | MP0002405_respiratory_system_inflammati | 1.02165036 |
| 68 | MP0006082_CNS_inflammation | 1.01891698 |
| 69 | MP0006035_abnormal_mitochondrial_morpho | 1.00509551 |
| 70 | MP0002272_abnormal_nervous_system | 0.98888481 |
| 71 | MP0008775_abnormal_heart_ventricle | 0.96406548 |
| 72 | MP0003300_gastrointestinal_ulcer | 0.95174582 |
| 73 | MP0002398_abnormal_bone_marrow | 0.91687599 |
| 74 | MP0001853_heart_inflammation | 0.91333924 |
| 75 | MP0001984_abnormal_olfaction | 0.89655702 |
| 76 | MP0010386_abnormal_urinary_bladder | 0.88398748 |
| 77 | MP0005410_abnormal_fertilization | 0.88045976 |
| 78 | MP0000716_abnormal_immune_system | 0.86512821 |
| 79 | MP0001929_abnormal_gametogenesis | 0.86266930 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.85514330 |
| 81 | MP0005636_abnormal_mineral_homeostasis | 0.84629891 |
| 82 | MP0002163_abnormal_gland_morphology | 0.84332929 |
| 83 | MP0002210_abnormal_sex_determination | 0.83539278 |
| 84 | MP0000689_abnormal_spleen_morphology | 0.81059585 |
| 85 | MP0009745_abnormal_behavioral_response | 0.78778918 |
| 86 | MP0003329_amyloid_beta_deposits | 0.78436722 |
| 87 | MP0006036_abnormal_mitochondrial_physio | 0.77420675 |
| 88 | MP0001905_abnormal_dopamine_level | 0.77043209 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.76222651 |
| 90 | MP0008469_abnormal_protein_level | 0.74554392 |
| 91 | MP0002277_abnormal_respiratory_mucosa | 0.74541498 |
| 92 | MP0001119_abnormal_female_reproductive | 0.73896396 |
| 93 | MP0001529_abnormal_vocalization | 0.73820390 |
| 94 | MP0002722_abnormal_immune_system | 0.73754662 |
| 95 | MP0002429_abnormal_blood_cell | 0.73690887 |
| 96 | MP0004019_abnormal_vitamin_homeostasis | 0.73244990 |
| 97 | MP0005253_abnormal_eye_physiology | 0.71786017 |
| 98 | MP0004133_heterotaxia | 0.71067406 |
| 99 | MP0003567_abnormal_fetal_cardiomyocyte | 0.70877340 |
| 100 | MP0002419_abnormal_innate_immunity | 0.67837586 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 6.22557802 |
| 2 | 3-Methylglutaconic aciduria (HP:0003535) | 4.05335416 |
| 3 | IgG deficiency (HP:0004315) | 3.78462315 |
| 4 | Increased IgM level (HP:0003496) | 3.74566908 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.67973461 |
| 6 | Lipid accumulation in hepatocytes (HP:0006561) | 3.54325054 |
| 7 | Acute necrotizing encephalopathy (HP:0006965) | 3.40671237 |
| 8 | Abnormality of alanine metabolism (HP:0010916) | 3.37359338 |
| 9 | Hyperalaninemia (HP:0003348) | 3.37359338 |
| 10 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.37359338 |
| 11 | Methylmalonic acidemia (HP:0002912) | 3.20646349 |
| 12 | Increased hepatocellular lipid droplets (HP:0006565) | 3.19337355 |
| 13 | Increased CSF lactate (HP:0002490) | 3.16035093 |
| 14 | Testicular atrophy (HP:0000029) | 3.13543698 |
| 15 | Congenital stationary night blindness (HP:0007642) | 3.09851545 |
| 16 | Acute encephalopathy (HP:0006846) | 3.08168577 |
| 17 | Prostate neoplasm (HP:0100787) | 3.05435508 |
| 18 | Congenital, generalized hypertrichosis (HP:0004540) | 3.04338330 |
| 19 | Mitochondrial inheritance (HP:0001427) | 3.03988515 |
| 20 | Optic disc pallor (HP:0000543) | 2.92770917 |
| 21 | Progressive macrocephaly (HP:0004481) | 2.90906289 |
| 22 | Increased serum lactate (HP:0002151) | 2.90329309 |
| 23 | Abnormality of the prostate (HP:0008775) | 2.88980070 |
| 24 | Methylmalonic aciduria (HP:0012120) | 2.82923604 |
| 25 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.78267174 |
| 26 | Asplenia (HP:0001746) | 2.68877507 |
| 27 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.68427373 |
| 28 | Pancreatic cysts (HP:0001737) | 2.67587646 |
| 29 | Abnormality of the renal cortex (HP:0011035) | 2.64945398 |
| 30 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.61416630 |
| 31 | Type II lissencephaly (HP:0007260) | 2.55581051 |
| 32 | IgA deficiency (HP:0002720) | 2.45065895 |
| 33 | Abnormality of T cell physiology (HP:0011840) | 2.43446954 |
| 34 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.41597786 |
| 35 | Polydipsia (HP:0001959) | 2.39744401 |
| 36 | Abnormal drinking behavior (HP:0030082) | 2.39744401 |
| 37 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.37159826 |
| 38 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.35389403 |
| 39 | Autoimmune thrombocytopenia (HP:0001973) | 2.34817415 |
| 40 | Hepatocellular necrosis (HP:0001404) | 2.28743802 |
| 41 | Parakeratosis (HP:0001036) | 2.26214735 |
| 42 | Renal cortical cysts (HP:0000803) | 2.23174846 |
| 43 | Dyschromatopsia (HP:0007641) | 2.22256490 |
| 44 | Renal Fanconi syndrome (HP:0001994) | 2.21226655 |
| 45 | Lactic acidosis (HP:0003128) | 2.18310814 |
| 46 | Autoimmune hemolytic anemia (HP:0001890) | 2.16678612 |
| 47 | Hepatic necrosis (HP:0002605) | 2.15869433 |
| 48 | Attenuation of retinal blood vessels (HP:0007843) | 2.14213997 |
| 49 | Nephronophthisis (HP:0000090) | 2.12676356 |
| 50 | Abnormality of the ileum (HP:0001549) | 2.11581133 |
| 51 | Meckel diverticulum (HP:0002245) | 2.10202908 |
| 52 | Central scotoma (HP:0000603) | 2.09738254 |
| 53 | Pendular nystagmus (HP:0012043) | 2.09259362 |
| 54 | Exertional dyspnea (HP:0002875) | 2.08508789 |
| 55 | Abnormality of T cells (HP:0002843) | 2.07843298 |
| 56 | Visual hallucinations (HP:0002367) | 2.06721310 |
| 57 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.06216769 |
| 58 | Decreased central vision (HP:0007663) | 2.06016930 |
| 59 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.05443721 |
| 60 | Recurrent cutaneous fungal infections (HP:0011370) | 2.03843230 |
| 61 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.03843230 |
| 62 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.03462473 |
| 63 | Cerebral edema (HP:0002181) | 2.01243019 |
| 64 | Abnormal number of erythroid precursors (HP:0012131) | 1.99998034 |
| 65 | Pancytopenia (HP:0001876) | 1.99410035 |
| 66 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.98200901 |
| 67 | Respiratory difficulties (HP:0002880) | 1.97320292 |
| 68 | Polyuria (HP:0000103) | 1.95068025 |
| 69 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.94207261 |
| 70 | Abolished electroretinogram (ERG) (HP:0000550) | 1.93599677 |
| 71 | Optic neuritis (HP:0100653) | 1.91563435 |
| 72 | Retrobulbar optic neuritis (HP:0100654) | 1.91563435 |
| 73 | Lethargy (HP:0001254) | 1.91069827 |
| 74 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.90950215 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.90853365 |
| 76 | Pancreatic fibrosis (HP:0100732) | 1.89862487 |
| 77 | Progressive inability to walk (HP:0002505) | 1.89557978 |
| 78 | Myositis (HP:0100614) | 1.89547252 |
| 79 | Tubular atrophy (HP:0000092) | 1.88248343 |
| 80 | Absent thumb (HP:0009777) | 1.87397523 |
| 81 | Keratoconjunctivitis (HP:0001096) | 1.86110227 |
| 82 | Abnormality of male internal genitalia (HP:0000022) | 1.85925617 |
| 83 | Glycosuria (HP:0003076) | 1.84937609 |
| 84 | Abnormality of urine glucose concentration (HP:0011016) | 1.84937609 |
| 85 | Partial agenesis of the corpus callosum (HP:0001338) | 1.84921641 |
| 86 | Colon cancer (HP:0003003) | 1.84125382 |
| 87 | Microvesicular hepatic steatosis (HP:0001414) | 1.83700411 |
| 88 | Increased muscle lipid content (HP:0009058) | 1.83413867 |
| 89 | Abnormal biliary tract physiology (HP:0012439) | 1.82741201 |
| 90 | Bile duct proliferation (HP:0001408) | 1.82741201 |
| 91 | Increased serum pyruvate (HP:0003542) | 1.82602929 |
| 92 | Clubbing of toes (HP:0100760) | 1.82067820 |
| 93 | Increased intramyocellular lipid droplets (HP:0012240) | 1.81356152 |
| 94 | Abnormality of midbrain morphology (HP:0002418) | 1.80910012 |
| 95 | Molar tooth sign on MRI (HP:0002419) | 1.80910012 |
| 96 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.79388748 |
| 97 | Absent/shortened dynein arms (HP:0200106) | 1.79388748 |
| 98 | Amniotic constriction ring (HP:0009775) | 1.78069576 |
| 99 | Abnormality of placental membranes (HP:0011409) | 1.78069576 |
| 100 | Respiratory failure (HP:0002878) | 1.76209135 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 3.72802031 |
| 2 | VRK2 | 3.17454552 |
| 3 | TRIM28 | 3.11875746 |
| 4 | NUAK1 | 3.11250587 |
| 5 | TLK1 | 3.06356048 |
| 6 | ADRBK2 | 3.00076012 |
| 7 | ZAK | 2.97553357 |
| 8 | TAOK3 | 2.80277625 |
| 9 | MST4 | 2.59535381 |
| 10 | BMPR1B | 2.33357873 |
| 11 | EIF2AK3 | 2.28941155 |
| 12 | TXK | 2.02973135 |
| 13 | STK16 | 2.01059984 |
| 14 | GRK1 | 1.97684104 |
| 15 | EIF2AK1 | 1.91958525 |
| 16 | VRK1 | 1.80649653 |
| 17 | MAPKAPK3 | 1.64639536 |
| 18 | TAF1 | 1.64195185 |
| 19 | OXSR1 | 1.60259583 |
| 20 | IKBKB | 1.53790794 |
| 21 | FES | 1.53766811 |
| 22 | MAP4K1 | 1.50071617 |
| 23 | NME1 | 1.50001105 |
| 24 | PBK | 1.43726416 |
| 25 | SRPK1 | 1.38378064 |
| 26 | NEK1 | 1.25939611 |
| 27 | MAP2K6 | 1.25186321 |
| 28 | EIF2AK2 | 1.21599873 |
| 29 | MKNK2 | 1.20685431 |
| 30 | PLK3 | 1.18956204 |
| 31 | DYRK2 | 1.17458787 |
| 32 | STK39 | 1.14243529 |
| 33 | CDK8 | 1.13626369 |
| 34 | RPS6KB2 | 1.12337048 |
| 35 | WNK4 | 1.09216031 |
| 36 | BUB1 | 1.08820397 |
| 37 | TEC | 1.06879963 |
| 38 | TSSK6 | 1.06444984 |
| 39 | GRK6 | 1.01724667 |
| 40 | TIE1 | 1.01708402 |
| 41 | KIT | 1.00304225 |
| 42 | ITK | 0.97613038 |
| 43 | IRAK1 | 0.96816859 |
| 44 | TGFBR1 | 0.96327180 |
| 45 | MAP3K14 | 0.95242815 |
| 46 | PASK | 0.93403585 |
| 47 | DAPK1 | 0.93176009 |
| 48 | DAPK2 | 0.92011690 |
| 49 | PDK2 | 0.89977015 |
| 50 | IRAK4 | 0.89862940 |
| 51 | RPS6KA4 | 0.87383347 |
| 52 | BCKDK | 0.84663621 |
| 53 | IKBKE | 0.84597993 |
| 54 | MAPKAPK5 | 0.82880598 |
| 55 | WNK3 | 0.81257687 |
| 56 | AKT3 | 0.79676061 |
| 57 | PHKG2 | 0.74360308 |
| 58 | PHKG1 | 0.74360308 |
| 59 | ADRBK1 | 0.74034202 |
| 60 | RPS6KA5 | 0.71373747 |
| 61 | CAMKK2 | 0.68448902 |
| 62 | MKNK1 | 0.68013221 |
| 63 | MAP2K2 | 0.64918663 |
| 64 | PLK2 | 0.64815850 |
| 65 | ATR | 0.61731139 |
| 66 | CSNK1G3 | 0.61422246 |
| 67 | PRKCQ | 0.59405976 |
| 68 | PRKCI | 0.57936554 |
| 69 | PRKCG | 0.55531541 |
| 70 | INSRR | 0.54995993 |
| 71 | GRK5 | 0.53897920 |
| 72 | MAP4K2 | 0.52910788 |
| 73 | PINK1 | 0.52356005 |
| 74 | MAP3K4 | 0.51175430 |
| 75 | MUSK | 0.49926956 |
| 76 | SIK3 | 0.49881820 |
| 77 | LYN | 0.49219395 |
| 78 | CSNK1A1L | 0.48642738 |
| 79 | PLK1 | 0.47521150 |
| 80 | BTK | 0.46780243 |
| 81 | CSNK1G2 | 0.45743385 |
| 82 | CSNK2A2 | 0.45522031 |
| 83 | CSNK1G1 | 0.43220909 |
| 84 | CSNK1A1 | 0.41438346 |
| 85 | PRKCD | 0.40904376 |
| 86 | EPHA3 | 0.40414369 |
| 87 | NME2 | 0.40006143 |
| 88 | PRKCE | 0.38085414 |
| 89 | LCK | 0.36574576 |
| 90 | CSNK2A1 | 0.36375414 |
| 91 | TBK1 | 0.34254400 |
| 92 | PRKCA | 0.34229210 |
| 93 | CDK7 | 0.34159598 |
| 94 | PLK4 | 0.33623073 |
| 95 | RPS6KB1 | 0.33019395 |
| 96 | CAMKK1 | 0.32436025 |
| 97 | SYK | 0.32250982 |
| 98 | AURKB | 0.31887724 |
| 99 | CASK | 0.31210026 |
| 100 | CAMK1 | 0.31135505 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.95339055 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.46592907 |
| 3 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.39813112 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.19269005 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.08326904 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.85217015 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.66098116 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.61592854 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.46703359 |
| 10 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.46461659 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.30686133 |
| 12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.08805569 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.04453552 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.99906845 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 1.90403271 |
| 16 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.85642963 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.84608787 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.83074898 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.71273157 |
| 20 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.63478154 |
| 21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.59633431 |
| 22 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.57527463 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.56134176 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.54645576 |
| 25 | Mismatch repair_Homo sapiens_hsa03430 | 1.48318554 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.48202329 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.28100773 |
| 28 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.27801221 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27163468 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.26507920 |
| 31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.22764966 |
| 32 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.18956888 |
| 33 | Spliceosome_Homo sapiens_hsa03040 | 1.18076721 |
| 34 | Alzheimers disease_Homo sapiens_hsa05010 | 1.17695677 |
| 35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.17292538 |
| 36 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.16210746 |
| 37 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.15676379 |
| 38 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.14335021 |
| 39 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.14197343 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.09515006 |
| 41 | RNA transport_Homo sapiens_hsa03013 | 1.09084627 |
| 42 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.06381873 |
| 43 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.05295266 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 1.02659176 |
| 45 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.00285486 |
| 46 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.98405899 |
| 47 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.97749659 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.96650889 |
| 49 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.94290591 |
| 50 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.93086226 |
| 51 | DNA replication_Homo sapiens_hsa03030 | 0.89396484 |
| 52 | Peroxisome_Homo sapiens_hsa04146 | 0.85893326 |
| 53 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.85772849 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.83418740 |
| 55 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.82332890 |
| 56 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.81353974 |
| 57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79021846 |
| 58 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.78840617 |
| 59 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.78299353 |
| 60 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.71573259 |
| 61 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.71040911 |
| 62 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.62217832 |
| 63 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.61385404 |
| 64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.60172854 |
| 65 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.59059110 |
| 66 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.58451782 |
| 67 | Olfactory transduction_Homo sapiens_hsa04740 | 0.55398786 |
| 68 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.54731105 |
| 69 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53993252 |
| 70 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.51685118 |
| 71 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.51390266 |
| 72 | Viral myocarditis_Homo sapiens_hsa05416 | 0.51214555 |
| 73 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.50906142 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.50766415 |
| 75 | Metabolic pathways_Homo sapiens_hsa01100 | 0.49322490 |
| 76 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.47217100 |
| 77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.46880491 |
| 78 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.46869807 |
| 79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45835146 |
| 80 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.43006703 |
| 81 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.42759345 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.42690396 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41731056 |
| 84 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.39615384 |
| 85 | Measles_Homo sapiens_hsa05162 | 0.39028448 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36776529 |
| 87 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36267888 |
| 88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.34293973 |
| 89 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.34282180 |
| 90 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.32386989 |
| 91 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.28870829 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.28706140 |
| 93 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.28537042 |
| 94 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28529980 |
| 95 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.28172578 |
| 96 | Leishmaniasis_Homo sapiens_hsa05140 | 0.26973511 |
| 97 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.25040754 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.24174579 |
| 99 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.23478337 |
| 100 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.23060532 |

