

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 6.98403916 |
| 2 | DNA deamination (GO:0045006) | 6.67975280 |
| 3 | viral transcription (GO:0019083) | 6.17361023 |
| 4 | ribosomal small subunit biogenesis (GO:0042274) | 5.96718749 |
| 5 | translational termination (GO:0006415) | 5.90426471 |
| 6 | cytidine metabolic process (GO:0046087) | 5.63726143 |
| 7 | cytidine catabolic process (GO:0006216) | 5.63726143 |
| 8 | cytidine deamination (GO:0009972) | 5.63726143 |
| 9 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.52031593 |
| 10 | translational elongation (GO:0006414) | 5.23072816 |
| 11 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.20401992 |
| 12 | maturation of SSU-rRNA (GO:0030490) | 5.15493250 |
| 13 | cotranslational protein targeting to membrane (GO:0006613) | 5.12433202 |
| 14 | protein targeting to ER (GO:0045047) | 5.11260588 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 5.10365584 |
| 16 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.10365584 |
| 17 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.07425393 |
| 18 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.86272471 |
| 19 | protein localization to endoplasmic reticulum (GO:0070972) | 4.82085591 |
| 20 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.80580713 |
| 21 | viral life cycle (GO:0019058) | 4.49675327 |
| 22 | ribosomal large subunit biogenesis (GO:0042273) | 4.47303152 |
| 23 | cellular protein complex disassembly (GO:0043624) | 4.44584775 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.30500580 |
| 25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.25139004 |
| 26 | translational initiation (GO:0006413) | 4.10328416 |
| 27 | respiratory electron transport chain (GO:0022904) | 4.04938130 |
| 28 | electron transport chain (GO:0022900) | 4.02142050 |
| 29 | protein complex biogenesis (GO:0070271) | 3.90793039 |
| 30 | chaperone-mediated protein transport (GO:0072321) | 3.82875005 |
| 31 | translation (GO:0006412) | 3.81488573 |
| 32 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.71704032 |
| 33 | protein neddylation (GO:0045116) | 3.67599746 |
| 34 | protein complex disassembly (GO:0043241) | 3.61697526 |
| 35 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.53865042 |
| 36 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.53352912 |
| 37 | NADH dehydrogenase complex assembly (GO:0010257) | 3.53352912 |
| 38 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.53352912 |
| 39 | macromolecular complex disassembly (GO:0032984) | 3.44220635 |
| 40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.43825845 |
| 41 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.43825845 |
| 42 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.38267410 |
| 43 | proteasome assembly (GO:0043248) | 3.31350338 |
| 44 | protein targeting to membrane (GO:0006612) | 3.31286442 |
| 45 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.30869048 |
| 46 | cellular component biogenesis (GO:0044085) | 3.28503853 |
| 47 | purine nucleotide salvage (GO:0032261) | 3.25415960 |
| 48 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.25132017 |
| 49 | platelet dense granule organization (GO:0060155) | 3.24835986 |
| 50 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.22960712 |
| 51 | base-excision repair, AP site formation (GO:0006285) | 3.19999159 |
| 52 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.12673630 |
| 53 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.12139272 |
| 54 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.09878567 |
| 55 | metallo-sulfur cluster assembly (GO:0031163) | 3.09350699 |
| 56 | iron-sulfur cluster assembly (GO:0016226) | 3.09350699 |
| 57 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.07069582 |
| 58 | behavioral response to nicotine (GO:0035095) | 3.05444143 |
| 59 | pseudouridine synthesis (GO:0001522) | 3.05126538 |
| 60 | deoxyribonucleotide catabolic process (GO:0009264) | 3.03831712 |
| 61 | actin nucleation (GO:0045010) | 2.99678340 |
| 62 | regulation of activation of Janus kinase activity (GO:0010533) | 2.99613534 |
| 63 | positive regulation of T cell apoptotic process (GO:0070234) | 2.99154892 |
| 64 | ATP biosynthetic process (GO:0006754) | 2.92980225 |
| 65 | mRNA catabolic process (GO:0006402) | 2.92267214 |
| 66 | response to pheromone (GO:0019236) | 2.90385367 |
| 67 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.88661408 |
| 68 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.86344938 |
| 69 | deoxyribose phosphate catabolic process (GO:0046386) | 2.85539310 |
| 70 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.83655010 |
| 71 | positive thymic T cell selection (GO:0045059) | 2.82345579 |
| 72 | ubiquinone biosynthetic process (GO:0006744) | 2.79198917 |
| 73 | negative regulation of T cell apoptotic process (GO:0070233) | 2.77517235 |
| 74 | cytochrome complex assembly (GO:0017004) | 2.77342469 |
| 75 | rRNA processing (GO:0006364) | 2.75401490 |
| 76 | negative regulation of mast cell activation (GO:0033004) | 2.75072458 |
| 77 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.72053958 |
| 78 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.71748562 |
| 79 | rRNA metabolic process (GO:0016072) | 2.70457416 |
| 80 | respiratory chain complex IV assembly (GO:0008535) | 2.70150402 |
| 81 | positive T cell selection (GO:0043368) | 2.69952698 |
| 82 | sequestering of actin monomers (GO:0042989) | 2.69527101 |
| 83 | RNA catabolic process (GO:0006401) | 2.68483956 |
| 84 | hydrogen ion transmembrane transport (GO:1902600) | 2.66585267 |
| 85 | ncRNA 3-end processing (GO:0043628) | 2.66481026 |
| 86 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.63667706 |
| 87 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.62844333 |
| 88 | negative regulation by host of viral transcription (GO:0043922) | 2.61484669 |
| 89 | male meiosis I (GO:0007141) | 2.61354716 |
| 90 | regulation of regulatory T cell differentiation (GO:0045589) | 2.61274325 |
| 91 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.61231814 |
| 92 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.60069546 |
| 93 | GTP biosynthetic process (GO:0006183) | 2.54125164 |
| 94 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.53291949 |
| 95 | cytolysis (GO:0019835) | 2.52626322 |
| 96 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.51904550 |
| 97 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.50604824 |
| 98 | protein targeting to mitochondrion (GO:0006626) | 2.50422621 |
| 99 | purine deoxyribonucleotide metabolic process (GO:0009151) | 2.50302115 |
| 100 | nucleotide salvage (GO:0043173) | 2.49644142 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.81922770 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.36146987 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.59316270 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.49717652 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.45365988 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.19649933 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.90489826 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.81485063 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.73979425 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.65469111 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.65440028 |
| 12 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.55565092 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.42929164 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.39358095 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.18577374 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.16812251 |
| 17 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.03438093 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.03044939 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.01880728 |
| 20 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.99522470 |
| 21 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.94242972 |
| 22 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.92450352 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.92315929 |
| 24 | VDR_22108803_ChIP-Seq_LS180_Human | 1.87726309 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.83752791 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.72308363 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71188883 |
| 28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.64403605 |
| 29 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.60713572 |
| 30 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57160003 |
| 31 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.54295555 |
| 32 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.52478206 |
| 33 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.49766032 |
| 34 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.49003340 |
| 35 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.48007962 |
| 36 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47460241 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.42423930 |
| 38 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.40854022 |
| 39 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.38935078 |
| 40 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.38854312 |
| 41 | MYB_26560356_Chip-Seq_TH2_Human | 1.36940272 |
| 42 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.36929020 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.34964628 |
| 44 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.34069764 |
| 45 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.32329795 |
| 46 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.30609639 |
| 47 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.30131981 |
| 48 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.29878448 |
| 49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.29544883 |
| 50 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.27938813 |
| 51 | AR_20517297_ChIP-Seq_VCAP_Human | 1.24660716 |
| 52 | EWS_26573619_Chip-Seq_HEK293_Human | 1.23367715 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.23174103 |
| 54 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.23174103 |
| 55 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.22846328 |
| 56 | NCOR_22424771_ChIP-Seq_293T_Human | 1.21728352 |
| 57 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.21633857 |
| 58 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20564206 |
| 59 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.20344412 |
| 60 | GATA3_26560356_Chip-Seq_TH2_Human | 1.18869434 |
| 61 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.18598313 |
| 62 | FUS_26573619_Chip-Seq_HEK293_Human | 1.18590779 |
| 63 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.16662130 |
| 64 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.15813615 |
| 65 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.15107900 |
| 66 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15052375 |
| 67 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.13066339 |
| 68 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.13042662 |
| 69 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.12008921 |
| 70 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09687850 |
| 71 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.09174523 |
| 72 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.08192263 |
| 73 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.06386677 |
| 74 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.03789467 |
| 75 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.03489833 |
| 76 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.03058676 |
| 77 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.02732638 |
| 78 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.01720532 |
| 79 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01226168 |
| 80 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.01044411 |
| 81 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.00680480 |
| 82 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.00680480 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00588495 |
| 84 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.00356620 |
| 85 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.99962992 |
| 86 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.98309823 |
| 87 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.98008660 |
| 88 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.97036401 |
| 89 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.96831288 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.96665458 |
| 91 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.96139327 |
| 92 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.96006362 |
| 93 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.95847495 |
| 94 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.94877963 |
| 95 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.93125187 |
| 96 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.92760702 |
| 97 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.91725959 |
| 98 | P300_27268052_Chip-Seq_Bcells_Human | 0.91470745 |
| 99 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.87064382 |
| 100 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.86552930 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.17198227 |
| 2 | MP0005671_abnormal_response_to | 3.78156204 |
| 3 | MP0006292_abnormal_olfactory_placode | 2.80307334 |
| 4 | MP0005646_abnormal_pituitary_gland | 2.39947398 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.20562760 |
| 6 | MP0002163_abnormal_gland_morphology | 2.16878319 |
| 7 | MP0009333_abnormal_splenocyte_physiolog | 2.14993946 |
| 8 | MP0004147_increased_porphyrin_level | 2.07266658 |
| 9 | MP0003646_muscle_fatigue | 2.04562540 |
| 10 | MP0000372_irregular_coat_pigmentation | 2.03823659 |
| 11 | MP0003763_abnormal_thymus_physiology | 1.99502020 |
| 12 | MP0002837_dystrophic_cardiac_calcinosis | 1.97042413 |
| 13 | MP0009785_altered_susceptibility_to | 1.94210184 |
| 14 | MP0002102_abnormal_ear_morphology | 1.89297998 |
| 15 | MP0003806_abnormal_nucleotide_metabolis | 1.88829152 |
| 16 | MP0005645_abnormal_hypothalamus_physiol | 1.87318129 |
| 17 | MP0008872_abnormal_physiological_respon | 1.75551800 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.70104398 |
| 19 | MP0002160_abnormal_reproductive_system | 1.67631902 |
| 20 | MP0002138_abnormal_hepatobiliary_system | 1.66935668 |
| 21 | MP0002148_abnormal_hypersensitivity_rea | 1.65980220 |
| 22 | MP0005551_abnormal_eye_electrophysiolog | 1.64620411 |
| 23 | MP0001764_abnormal_homeostasis | 1.61886614 |
| 24 | MP0002638_abnormal_pupillary_reflex | 1.59941672 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.58306560 |
| 26 | MP0005389_reproductive_system_phenotype | 1.57778061 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.56026799 |
| 28 | MP0001800_abnormal_humoral_immune | 1.55728259 |
| 29 | MP0004142_abnormal_muscle_tone | 1.46907401 |
| 30 | MP0005000_abnormal_immune_tolerance | 1.44104435 |
| 31 | MP0002420_abnormal_adaptive_immunity | 1.43228090 |
| 32 | MP0002736_abnormal_nociception_after | 1.39077311 |
| 33 | MP0005075_abnormal_melanosome_morpholog | 1.38896781 |
| 34 | MP0001819_abnormal_immune_cell | 1.38249502 |
| 35 | MP0003786_premature_aging | 1.38054441 |
| 36 | MP0001188_hyperpigmentation | 1.37929729 |
| 37 | MP0001919_abnormal_reproductive_system | 1.37686800 |
| 38 | MP0002723_abnormal_immune_serum | 1.37395444 |
| 39 | MP0006276_abnormal_autonomic_nervous | 1.37274619 |
| 40 | MP0005025_abnormal_response_to | 1.33967393 |
| 41 | MP0004145_abnormal_muscle_electrophysio | 1.33817239 |
| 42 | MP0001905_abnormal_dopamine_level | 1.33152069 |
| 43 | MP0002095_abnormal_skin_pigmentation | 1.29919100 |
| 44 | MP0005379_endocrine/exocrine_gland_phen | 1.29297323 |
| 45 | MP0006036_abnormal_mitochondrial_physio | 1.29086489 |
| 46 | MP0008877_abnormal_DNA_methylation | 1.28266026 |
| 47 | MP0005084_abnormal_gallbladder_morpholo | 1.26774111 |
| 48 | MP0002876_abnormal_thyroid_physiology | 1.23768447 |
| 49 | MP0002277_abnormal_respiratory_mucosa | 1.20306600 |
| 50 | MP0005083_abnormal_biliary_tract | 1.20306289 |
| 51 | MP0003878_abnormal_ear_physiology | 1.19966768 |
| 52 | MP0005377_hearing/vestibular/ear_phenot | 1.19966768 |
| 53 | MP0002398_abnormal_bone_marrow | 1.18285277 |
| 54 | MP0000716_abnormal_immune_system | 1.18219319 |
| 55 | MP0000685_abnormal_immune_system | 1.16566417 |
| 56 | MP0003252_abnormal_bile_duct | 1.13263661 |
| 57 | MP0005387_immune_system_phenotype | 1.12992063 |
| 58 | MP0001790_abnormal_immune_system | 1.12992063 |
| 59 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12707558 |
| 60 | MP0008058_abnormal_DNA_repair | 1.11487910 |
| 61 | MP0002452_abnormal_antigen_presenting | 1.09320587 |
| 62 | MP0005253_abnormal_eye_physiology | 1.08409646 |
| 63 | MP0001873_stomach_inflammation | 1.07647219 |
| 64 | MP0002166_altered_tumor_susceptibility | 1.06923524 |
| 65 | MP0008789_abnormal_olfactory_epithelium | 1.06069570 |
| 66 | MP0004885_abnormal_endolymph | 1.04134812 |
| 67 | MP0005174_abnormal_tail_pigmentation | 1.00402328 |
| 68 | MP0002006_tumorigenesis | 0.99830159 |
| 69 | MP0002234_abnormal_pharynx_morphology | 0.96294148 |
| 70 | MP0005636_abnormal_mineral_homeostasis | 0.96260224 |
| 71 | MP0000703_abnormal_thymus_morphology | 0.96161316 |
| 72 | MP0003866_abnormal_defecation | 0.95600899 |
| 73 | MP0008995_early_reproductive_senescence | 0.95123284 |
| 74 | MP0000689_abnormal_spleen_morphology | 0.94021994 |
| 75 | MP0002429_abnormal_blood_cell | 0.91927349 |
| 76 | MP0002405_respiratory_system_inflammati | 0.91278999 |
| 77 | MP0002272_abnormal_nervous_system | 0.90271631 |
| 78 | MP0005410_abnormal_fertilization | 0.89599148 |
| 79 | MP0001986_abnormal_taste_sensitivity | 0.89339871 |
| 80 | MP0003186_abnormal_redox_activity | 0.88625044 |
| 81 | MP0000049_abnormal_middle_ear | 0.87862250 |
| 82 | MP0002132_abnormal_respiratory_system | 0.87076193 |
| 83 | MP0000631_abnormal_neuroendocrine_gland | 0.85404850 |
| 84 | MP0002722_abnormal_immune_system | 0.85105757 |
| 85 | MP0002733_abnormal_thermal_nociception | 0.82812106 |
| 86 | MP0006082_CNS_inflammation | 0.81442914 |
| 87 | MP0005085_abnormal_gallbladder_physiolo | 0.81174270 |
| 88 | MP0003011_delayed_dark_adaptation | 0.79274501 |
| 89 | MP0001485_abnormal_pinna_reflex | 0.77396856 |
| 90 | MP0003787_abnormal_imprinting | 0.75652015 |
| 91 | MP0009745_abnormal_behavioral_response | 0.75167845 |
| 92 | MP0003195_calcinosis | 0.73685008 |
| 93 | MP0010386_abnormal_urinary_bladder | 0.72086753 |
| 94 | MP0005464_abnormal_platelet_physiology | 0.71730381 |
| 95 | MP0010155_abnormal_intestine_physiology | 0.71254082 |
| 96 | MP0002653_abnormal_ependyma_morphology | 0.70567119 |
| 97 | MP0009643_abnormal_urine_homeostasis | 0.69325779 |
| 98 | MP0001845_abnormal_inflammatory_respons | 0.69078540 |
| 99 | MP0001970_abnormal_pain_threshold | 0.68879707 |
| 100 | MP0009764_decreased_sensitivity_to | 0.68783978 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.53805735 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.39200324 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.25586879 |
| 4 | Congenital stationary night blindness (HP:0007642) | 4.13075443 |
| 5 | 3-Methylglutaconic aciduria (HP:0003535) | 4.03226778 |
| 6 | Aplastic anemia (HP:0001915) | 3.82966285 |
| 7 | Increased CSF lactate (HP:0002490) | 3.81054391 |
| 8 | Reticulocytopenia (HP:0001896) | 3.76165050 |
| 9 | Acute encephalopathy (HP:0006846) | 3.74945636 |
| 10 | Increased hepatocellular lipid droplets (HP:0006565) | 3.69812600 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.67588306 |
| 12 | Increased intramyocellular lipid droplets (HP:0012240) | 3.67473390 |
| 13 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.52621215 |
| 14 | Hepatocellular necrosis (HP:0001404) | 3.39237345 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.26411843 |
| 16 | Abnormal number of erythroid precursors (HP:0012131) | 3.22411847 |
| 17 | Macrocytic anemia (HP:0001972) | 3.21742259 |
| 18 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.21374612 |
| 19 | Lipid accumulation in hepatocytes (HP:0006561) | 3.21117730 |
| 20 | Hepatic necrosis (HP:0002605) | 3.09621767 |
| 21 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.08966729 |
| 22 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.08966729 |
| 23 | Cerebral edema (HP:0002181) | 3.04397326 |
| 24 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.98915920 |
| 25 | Increased muscle lipid content (HP:0009058) | 2.96609483 |
| 26 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.94658648 |
| 27 | Pancreatic cysts (HP:0001737) | 2.91795614 |
| 28 | Severe combined immunodeficiency (HP:0004430) | 2.91722308 |
| 29 | IgG deficiency (HP:0004315) | 2.90948421 |
| 30 | Autoimmune hemolytic anemia (HP:0001890) | 2.77631560 |
| 31 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.73817919 |
| 32 | Pallor (HP:0000980) | 2.68311244 |
| 33 | Abnormality of midbrain morphology (HP:0002418) | 2.67246373 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.67246373 |
| 35 | Optic disc pallor (HP:0000543) | 2.63486253 |
| 36 | Pancreatic fibrosis (HP:0100732) | 2.57471490 |
| 37 | True hermaphroditism (HP:0010459) | 2.56745641 |
| 38 | Exertional dyspnea (HP:0002875) | 2.55376017 |
| 39 | Lactic acidosis (HP:0003128) | 2.52207266 |
| 40 | Increased serum lactate (HP:0002151) | 2.48888958 |
| 41 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.46248681 |
| 42 | Hypoproteinemia (HP:0003075) | 2.43634950 |
| 43 | Abnormality of the prostate (HP:0008775) | 2.35522116 |
| 44 | Abnormality of T cell number (HP:0011839) | 2.33636248 |
| 45 | Respiratory difficulties (HP:0002880) | 2.32151314 |
| 46 | Increased IgM level (HP:0003496) | 2.31674341 |
| 47 | T lymphocytopenia (HP:0005403) | 2.29324586 |
| 48 | Abnormality of the renal cortex (HP:0011035) | 2.26170206 |
| 49 | Pancytopenia (HP:0001876) | 2.25051026 |
| 50 | Abnormality of B cell number (HP:0010975) | 2.23625639 |
| 51 | Abolished electroretinogram (ERG) (HP:0000550) | 2.23008905 |
| 52 | Abnormality of T cells (HP:0002843) | 2.21239444 |
| 53 | Glycosuria (HP:0003076) | 2.20637278 |
| 54 | Abnormality of urine glucose concentration (HP:0011016) | 2.20637278 |
| 55 | Panhypogammaglobulinemia (HP:0003139) | 2.18563173 |
| 56 | Hyperphosphaturia (HP:0003109) | 2.17765294 |
| 57 | Respiratory failure (HP:0002878) | 2.17461150 |
| 58 | Stenosis of the external auditory canal (HP:0000402) | 2.17394785 |
| 59 | Absent thumb (HP:0009777) | 2.17038450 |
| 60 | Exercise intolerance (HP:0003546) | 2.14332347 |
| 61 | Testicular atrophy (HP:0000029) | 2.13563273 |
| 62 | Combined immunodeficiency (HP:0005387) | 2.11109024 |
| 63 | Severe visual impairment (HP:0001141) | 2.10900392 |
| 64 | Abnormality of renal resorption (HP:0011038) | 2.10593055 |
| 65 | Lethargy (HP:0001254) | 2.09000402 |
| 66 | Attenuation of retinal blood vessels (HP:0007843) | 2.05690906 |
| 67 | Abnormality of DNA repair (HP:0003254) | 2.05456375 |
| 68 | Nephronophthisis (HP:0000090) | 2.04997300 |
| 69 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.04641793 |
| 70 | Thyroiditis (HP:0100646) | 2.03252961 |
| 71 | Agammaglobulinemia (HP:0004432) | 1.98165732 |
| 72 | Renal cortical cysts (HP:0000803) | 1.97921219 |
| 73 | Stomatitis (HP:0010280) | 1.97901482 |
| 74 | Methylmalonic aciduria (HP:0012120) | 1.95548690 |
| 75 | Pendular nystagmus (HP:0012043) | 1.95151987 |
| 76 | Type 2 muscle fiber atrophy (HP:0003554) | 1.93024951 |
| 77 | Sclerocornea (HP:0000647) | 1.93021099 |
| 78 | Medial flaring of the eyebrow (HP:0010747) | 1.92943862 |
| 79 | Decreased central vision (HP:0007663) | 1.92713666 |
| 80 | Hypoplasia of the uterus (HP:0000013) | 1.91208226 |
| 81 | B lymphocytopenia (HP:0010976) | 1.89903371 |
| 82 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.89161896 |
| 83 | Polydipsia (HP:0001959) | 1.88984666 |
| 84 | Abnormal drinking behavior (HP:0030082) | 1.88984666 |
| 85 | Methylmalonic acidemia (HP:0002912) | 1.87679522 |
| 86 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.86923180 |
| 87 | Dicarboxylic aciduria (HP:0003215) | 1.86923180 |
| 88 | Abnormality of eosinophils (HP:0001879) | 1.86699423 |
| 89 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.86317766 |
| 90 | Ketosis (HP:0001946) | 1.86033485 |
| 91 | Abnormality of the renal collecting system (HP:0004742) | 1.85234042 |
| 92 | Generalized aminoaciduria (HP:0002909) | 1.83298087 |
| 93 | Constricted visual fields (HP:0001133) | 1.83035944 |
| 94 | Type I transferrin isoform profile (HP:0003642) | 1.81999935 |
| 95 | Asplenia (HP:0001746) | 1.81895379 |
| 96 | Hyperglycinemia (HP:0002154) | 1.81273021 |
| 97 | Encephalitis (HP:0002383) | 1.81152418 |
| 98 | Prostate neoplasm (HP:0100787) | 1.80607507 |
| 99 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.80412999 |
| 100 | Leukodystrophy (HP:0002415) | 1.78373873 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 4.10383472 |
| 2 | KDR | 4.10125010 |
| 3 | TXK | 3.46096831 |
| 4 | VRK2 | 2.93080033 |
| 5 | BCKDK | 2.90893010 |
| 6 | ADRBK2 | 2.73054831 |
| 7 | GRK1 | 2.66863272 |
| 8 | MAP4K2 | 2.60668510 |
| 9 | ZAK | 2.29944430 |
| 10 | TIE1 | 2.21080518 |
| 11 | CDK19 | 2.08242457 |
| 12 | TAOK3 | 2.05326133 |
| 13 | MAP4K1 | 2.02955947 |
| 14 | STK16 | 1.95798787 |
| 15 | TLK1 | 1.93124638 |
| 16 | VRK1 | 1.86439717 |
| 17 | LIMK1 | 1.81702136 |
| 18 | ITK | 1.80575769 |
| 19 | NUAK1 | 1.74514862 |
| 20 | TEC | 1.65987502 |
| 21 | NME2 | 1.64057939 |
| 22 | MAP3K11 | 1.56089754 |
| 23 | MAP3K12 | 1.54277918 |
| 24 | SCYL2 | 1.50560969 |
| 25 | WNK4 | 1.42867865 |
| 26 | PASK | 1.39187287 |
| 27 | SYK | 1.38545538 |
| 28 | CAMKK2 | 1.36302388 |
| 29 | PINK1 | 1.31985486 |
| 30 | FES | 1.26039248 |
| 31 | PRKCQ | 1.09119467 |
| 32 | BUB1 | 1.06212715 |
| 33 | DAPK1 | 1.02462898 |
| 34 | INSRR | 0.99959262 |
| 35 | GRK6 | 0.99522543 |
| 36 | CCNB1 | 0.96892164 |
| 37 | TNK2 | 0.93657918 |
| 38 | AURKA | 0.90875513 |
| 39 | IKBKB | 0.88603533 |
| 40 | DYRK2 | 0.88049028 |
| 41 | BMPR1B | 0.87528532 |
| 42 | BTK | 0.85893677 |
| 43 | KIT | 0.82412531 |
| 44 | MST4 | 0.81601079 |
| 45 | FRK | 0.80777589 |
| 46 | LCK | 0.80103613 |
| 47 | ADRBK1 | 0.78012504 |
| 48 | PIM1 | 0.77421765 |
| 49 | TESK1 | 0.72615596 |
| 50 | LYN | 0.69756366 |
| 51 | GRK7 | 0.69450093 |
| 52 | PIK3CA | 0.68261182 |
| 53 | LRRK2 | 0.68020506 |
| 54 | MAP2K6 | 0.63927626 |
| 55 | CSF1R | 0.63082193 |
| 56 | PLK4 | 0.62991628 |
| 57 | IKBKE | 0.62940476 |
| 58 | WNK3 | 0.62468544 |
| 59 | OBSCN | 0.61435109 |
| 60 | RPS6KA5 | 0.60943973 |
| 61 | CDC7 | 0.59901343 |
| 62 | NME1 | 0.59470849 |
| 63 | CAMKK1 | 0.59319036 |
| 64 | DAPK2 | 0.58805642 |
| 65 | PIM2 | 0.58750828 |
| 66 | PDK2 | 0.58290737 |
| 67 | TAF1 | 0.57960530 |
| 68 | MYLK | 0.57127684 |
| 69 | CAMK1 | 0.54932292 |
| 70 | RPS6KA4 | 0.53332723 |
| 71 | CSNK1G3 | 0.52776200 |
| 72 | CSNK2A1 | 0.51667165 |
| 73 | CSNK2A2 | 0.50906081 |
| 74 | ABL2 | 0.50664343 |
| 75 | OXSR1 | 0.50347273 |
| 76 | DAPK3 | 0.47589986 |
| 77 | PRKACA | 0.46166506 |
| 78 | ATR | 0.45985430 |
| 79 | BMPR2 | 0.45772130 |
| 80 | PRKCA | 0.44605440 |
| 81 | CSK | 0.43871543 |
| 82 | MUSK | 0.42488988 |
| 83 | SRPK1 | 0.42330776 |
| 84 | MAPK13 | 0.41942667 |
| 85 | ZAP70 | 0.40994697 |
| 86 | CDK8 | 0.40339439 |
| 87 | IGF1R | 0.40128447 |
| 88 | CSNK1G2 | 0.39423178 |
| 89 | GRK5 | 0.39059630 |
| 90 | PRKCH | 0.38587715 |
| 91 | BRSK2 | 0.38480138 |
| 92 | MAP2K7 | 0.38177067 |
| 93 | MAPKAPK3 | 0.37549955 |
| 94 | MATK | 0.37415568 |
| 95 | PLK1 | 0.35581208 |
| 96 | STK39 | 0.34486865 |
| 97 | AURKB | 0.34479044 |
| 98 | ILK | 0.33517371 |
| 99 | MAPK15 | 0.33199527 |
| 100 | RPS6KA6 | 0.32180553 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.47539433 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.97049802 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.64977272 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.53365925 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.31893522 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.21617586 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.14690857 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.04583873 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.03152939 |
| 10 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.03045482 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.01209774 |
| 12 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.96763132 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.88845723 |
| 14 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.79521813 |
| 15 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.72636015 |
| 16 | Phototransduction_Homo sapiens_hsa04744 | 1.71931917 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.67517553 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.66826062 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.65951455 |
| 20 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.65863712 |
| 21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.61848781 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.58910674 |
| 23 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.57444326 |
| 24 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.45807037 |
| 25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.44388942 |
| 26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.43315250 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.42998463 |
| 28 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.39074811 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.38305340 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.23677352 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.22999257 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.19473962 |
| 33 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.15365145 |
| 34 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.14976398 |
| 35 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.10353104 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.08836763 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.07795289 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.06099993 |
| 39 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.04395660 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.02487422 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 1.00789746 |
| 42 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.93972058 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 0.93148550 |
| 44 | Retinol metabolism_Homo sapiens_hsa00830 | 0.92787733 |
| 45 | Mismatch repair_Homo sapiens_hsa03430 | 0.91566484 |
| 46 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.89747023 |
| 47 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87961810 |
| 48 | Basal transcription factors_Homo sapiens_hsa03022 | 0.87472256 |
| 49 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87100080 |
| 50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.86919414 |
| 51 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.85685841 |
| 52 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.85358085 |
| 53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.84455588 |
| 54 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83633896 |
| 55 | Spliceosome_Homo sapiens_hsa03040 | 0.81465568 |
| 56 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.77594446 |
| 57 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.77486989 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75308360 |
| 59 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.74920251 |
| 60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.72283515 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.71230099 |
| 62 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.69425309 |
| 63 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.69035357 |
| 64 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.65642825 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.65416939 |
| 66 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.64107247 |
| 67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.63706166 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63080366 |
| 69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62747946 |
| 70 | RNA transport_Homo sapiens_hsa03013 | 0.59305998 |
| 71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.57351704 |
| 72 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.56580405 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.56025670 |
| 74 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.55099928 |
| 75 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49383653 |
| 76 | Nicotine addiction_Homo sapiens_hsa05033 | 0.48314526 |
| 77 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.47760884 |
| 78 | Viral myocarditis_Homo sapiens_hsa05416 | 0.46021520 |
| 79 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45977180 |
| 80 | Malaria_Homo sapiens_hsa05144 | 0.45421559 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.43761601 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.40313877 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39973648 |
| 84 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.39410269 |
| 85 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.39296712 |
| 86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.39232843 |
| 87 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36455022 |
| 88 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.35196876 |
| 89 | Measles_Homo sapiens_hsa05162 | 0.33235361 |
| 90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.30936154 |
| 91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.30288792 |
| 92 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.29868739 |
| 93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.28941561 |
| 94 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.26808939 |
| 95 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.22532026 |
| 96 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.20557809 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.16383016 |
| 98 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.15615036 |
| 99 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.15070431 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.15030936 |

