

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.77609380 |
| 2 | ribosomal large subunit biogenesis (GO:0042273) | 7.05541612 |
| 3 | viral transcription (GO:0019083) | 6.72838005 |
| 4 | translational termination (GO:0006415) | 6.52460981 |
| 5 | ribosomal small subunit biogenesis (GO:0042274) | 6.27982214 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 5.85331615 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.85331615 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.53104829 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.51537283 |
| 10 | translational elongation (GO:0006414) | 5.47813165 |
| 11 | protein targeting to ER (GO:0045047) | 5.40851101 |
| 12 | cotranslational protein targeting to membrane (GO:0006613) | 5.40643280 |
| 13 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.17552450 |
| 14 | protein localization to endoplasmic reticulum (GO:0070972) | 5.05756971 |
| 15 | cellular protein complex disassembly (GO:0043624) | 4.85420681 |
| 16 | maturation of SSU-rRNA (GO:0030490) | 4.85174941 |
| 17 | viral life cycle (GO:0019058) | 4.76828914 |
| 18 | piRNA metabolic process (GO:0034587) | 4.68530388 |
| 19 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.66158426 |
| 20 | protein neddylation (GO:0045116) | 4.64007424 |
| 21 | peptidyl-histidine modification (GO:0018202) | 4.45451914 |
| 22 | response to pheromone (GO:0019236) | 4.39869284 |
| 23 | translational initiation (GO:0006413) | 4.37017059 |
| 24 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.32768760 |
| 25 | protein complex disassembly (GO:0043241) | 3.99236755 |
| 26 | respiratory electron transport chain (GO:0022904) | 3.95201563 |
| 27 | electron transport chain (GO:0022900) | 3.93657086 |
| 28 | behavioral response to nicotine (GO:0035095) | 3.91056663 |
| 29 | DNA deamination (GO:0045006) | 3.90689997 |
| 30 | translation (GO:0006412) | 3.90171559 |
| 31 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.89131328 |
| 32 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.80040689 |
| 33 | macromolecular complex disassembly (GO:0032984) | 3.78616780 |
| 34 | cellular component biogenesis (GO:0044085) | 3.58293551 |
| 35 | chaperone-mediated protein transport (GO:0072321) | 3.56150331 |
| 36 | protein targeting to membrane (GO:0006612) | 3.52651738 |
| 37 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.47158376 |
| 38 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.47158376 |
| 39 | ATP biosynthetic process (GO:0006754) | 3.46936453 |
| 40 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.46068585 |
| 41 | negative regulation of mast cell activation (GO:0033004) | 3.45932584 |
| 42 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.43932035 |
| 43 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.43834957 |
| 44 | GTP biosynthetic process (GO:0006183) | 3.34418044 |
| 45 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.33726372 |
| 46 | protein complex biogenesis (GO:0070271) | 3.27393488 |
| 47 | glycerophospholipid catabolic process (GO:0046475) | 3.26909909 |
| 48 | mRNA catabolic process (GO:0006402) | 3.22670617 |
| 49 | termination of RNA polymerase III transcription (GO:0006386) | 3.19305651 |
| 50 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.19305651 |
| 51 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.18805265 |
| 52 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.17214293 |
| 53 | positive regulation of interleukin-17 production (GO:0032740) | 3.16559770 |
| 54 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.16096117 |
| 55 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.16096117 |
| 56 | NADH dehydrogenase complex assembly (GO:0010257) | 3.16096117 |
| 57 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.15820982 |
| 58 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.13996348 |
| 59 | hydrogen ion transmembrane transport (GO:1902600) | 3.12008772 |
| 60 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.07370294 |
| 61 | rRNA processing (GO:0006364) | 2.99052701 |
| 62 | male meiosis I (GO:0007141) | 2.98615794 |
| 63 | RNA catabolic process (GO:0006401) | 2.92803307 |
| 64 | leukotriene biosynthetic process (GO:0019370) | 2.91309885 |
| 65 | rRNA metabolic process (GO:0016072) | 2.89776980 |
| 66 | nonribosomal peptide biosynthetic process (GO:0019184) | 2.89760121 |
| 67 | respiratory chain complex IV assembly (GO:0008535) | 2.89751462 |
| 68 | transcription from mitochondrial promoter (GO:0006390) | 2.89695209 |
| 69 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.88977245 |
| 70 | proton transport (GO:0015992) | 2.86365170 |
| 71 | seminiferous tubule development (GO:0072520) | 2.85938985 |
| 72 | hydrogen transport (GO:0006818) | 2.78839497 |
| 73 | pseudouridine synthesis (GO:0001522) | 2.75290469 |
| 74 | glutathione biosynthetic process (GO:0006750) | 2.73696403 |
| 75 | indolalkylamine metabolic process (GO:0006586) | 2.73330013 |
| 76 | positive regulation of mitochondrial fission (GO:0090141) | 2.72739487 |
| 77 | tRNA processing (GO:0008033) | 2.67181712 |
| 78 | protein-cofactor linkage (GO:0018065) | 2.67060927 |
| 79 | UTP biosynthetic process (GO:0006228) | 2.64050971 |
| 80 | ribosome assembly (GO:0042255) | 2.62268331 |
| 81 | mitochondrial calcium ion transport (GO:0006851) | 2.57948226 |
| 82 | proteasome assembly (GO:0043248) | 2.57427990 |
| 83 | nucleobase catabolic process (GO:0046113) | 2.56332618 |
| 84 | maturation of 5.8S rRNA (GO:0000460) | 2.55050572 |
| 85 | protein targeting to mitochondrion (GO:0006626) | 2.54308538 |
| 86 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.52480721 |
| 87 | UTP metabolic process (GO:0046051) | 2.52025818 |
| 88 | oxidative phosphorylation (GO:0006119) | 2.51806384 |
| 89 | dopamine transport (GO:0015872) | 2.51777927 |
| 90 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.50389891 |
| 91 | regulation of activation of Janus kinase activity (GO:0010533) | 2.49443718 |
| 92 | intracellular protein transmembrane import (GO:0044743) | 2.48273276 |
| 93 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.48253454 |
| 94 | protein targeting (GO:0006605) | 2.46603172 |
| 95 | cytochrome complex assembly (GO:0017004) | 2.46571064 |
| 96 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.46349239 |
| 97 | negative regulation of telomere maintenance (GO:0032205) | 2.46113291 |
| 98 | meiosis I (GO:0007127) | 2.45576961 |
| 99 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.44923035 |
| 100 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.43506419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 4.10815666 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.09352842 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.35872898 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.20290050 |
| 5 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.12292958 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.08034911 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.03986292 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.92782768 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.78409816 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.73727848 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.42481368 |
| 12 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.30325773 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.18798293 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.17597571 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.10746045 |
| 16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.02621034 |
| 17 | FUS_26573619_Chip-Seq_HEK293_Human | 1.99510686 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.97477978 |
| 19 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.93500217 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.86581735 |
| 21 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.82712480 |
| 22 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.81779541 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.78155516 |
| 24 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77714041 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.76090339 |
| 26 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.67023784 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.63982268 |
| 28 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.60920597 |
| 29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.57430190 |
| 30 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.56641028 |
| 31 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.53192740 |
| 32 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.52370251 |
| 33 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.46493576 |
| 34 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.45826682 |
| 35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.42971246 |
| 36 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.41023799 |
| 37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.40641542 |
| 38 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.39994264 |
| 39 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.38513217 |
| 40 | NCOR_22424771_ChIP-Seq_293T_Human | 1.37513996 |
| 41 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.36481188 |
| 42 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.35619868 |
| 43 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.33886353 |
| 44 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.33072333 |
| 45 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.30274589 |
| 46 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.30274589 |
| 47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.29913364 |
| 48 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.27984725 |
| 49 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.26887701 |
| 50 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.21777340 |
| 51 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.21061854 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.21061854 |
| 53 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.19385427 |
| 54 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18913025 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.17863474 |
| 56 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.17769188 |
| 57 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.17739348 |
| 58 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.16136347 |
| 59 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.15760105 |
| 60 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15044385 |
| 61 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.13994759 |
| 62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.13994759 |
| 63 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.12072329 |
| 64 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.12065284 |
| 65 | ERA_21632823_ChIP-Seq_H3396_Human | 1.11436564 |
| 66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10929104 |
| 67 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.09100621 |
| 68 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.06344479 |
| 69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.05580646 |
| 70 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.04876962 |
| 71 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.04090581 |
| 72 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03915622 |
| 73 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.03677612 |
| 74 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.03103501 |
| 75 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.02268710 |
| 76 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.01903274 |
| 77 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.01678562 |
| 78 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.98852196 |
| 79 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.98283932 |
| 80 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.98052603 |
| 81 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.97530446 |
| 82 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97448661 |
| 83 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.97315915 |
| 84 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.94878005 |
| 85 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.93662671 |
| 86 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.93122005 |
| 87 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.92299822 |
| 88 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91211930 |
| 89 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.90841575 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.90241327 |
| 91 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.90214040 |
| 92 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.89399810 |
| 93 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.88358735 |
| 94 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.87909298 |
| 95 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.86489650 |
| 96 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.85022356 |
| 97 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.84860069 |
| 98 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.84785644 |
| 99 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.83699465 |
| 100 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.83028246 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 3.50724522 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.47407136 |
| 3 | MP0005646_abnormal_pituitary_gland | 2.77261998 |
| 4 | MP0004142_abnormal_muscle_tone | 2.63433569 |
| 5 | MP0002638_abnormal_pupillary_reflex | 2.55932508 |
| 6 | MP0003195_calcinosis | 2.54023480 |
| 7 | MP0003646_muscle_fatigue | 2.49731694 |
| 8 | MP0003787_abnormal_imprinting | 2.12225664 |
| 9 | MP0002163_abnormal_gland_morphology | 2.10136492 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.05213862 |
| 11 | MP0002102_abnormal_ear_morphology | 2.05129803 |
| 12 | MP0005645_abnormal_hypothalamus_physiol | 1.97800170 |
| 13 | MP0001986_abnormal_taste_sensitivity | 1.94064549 |
| 14 | MP0001968_abnormal_touch/_nociception | 1.92947397 |
| 15 | MP0005671_abnormal_response_to | 1.92167464 |
| 16 | MP0001905_abnormal_dopamine_level | 1.88861233 |
| 17 | MP0003786_premature_aging | 1.82941493 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.81749686 |
| 19 | MP0002876_abnormal_thyroid_physiology | 1.75954242 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 1.75715481 |
| 21 | MP0008872_abnormal_physiological_respon | 1.74835132 |
| 22 | MP0002272_abnormal_nervous_system | 1.73593035 |
| 23 | MP0005075_abnormal_melanosome_morpholog | 1.73193098 |
| 24 | MP0000631_abnormal_neuroendocrine_gland | 1.72141956 |
| 25 | MP0008995_early_reproductive_senescence | 1.68511123 |
| 26 | MP0001529_abnormal_vocalization | 1.66642323 |
| 27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.64517167 |
| 28 | MP0004133_heterotaxia | 1.64496748 |
| 29 | MP0006072_abnormal_retinal_apoptosis | 1.63397478 |
| 30 | MP0002736_abnormal_nociception_after | 1.60610825 |
| 31 | MP0004147_increased_porphyrin_level | 1.54572102 |
| 32 | MP0006276_abnormal_autonomic_nervous | 1.54069654 |
| 33 | MP0005379_endocrine/exocrine_gland_phen | 1.52834882 |
| 34 | MP0003011_delayed_dark_adaptation | 1.44682975 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.42776313 |
| 36 | MP0009745_abnormal_behavioral_response | 1.41911604 |
| 37 | MP0002733_abnormal_thermal_nociception | 1.41306153 |
| 38 | MP0009046_muscle_twitch | 1.38969231 |
| 39 | MP0003880_abnormal_central_pattern | 1.37579879 |
| 40 | MP0010386_abnormal_urinary_bladder | 1.28349449 |
| 41 | MP0004742_abnormal_vestibular_system | 1.26474436 |
| 42 | MP0002572_abnormal_emotion/affect_behav | 1.25848617 |
| 43 | MP0001970_abnormal_pain_threshold | 1.25551149 |
| 44 | MP0008775_abnormal_heart_ventricle | 1.23847482 |
| 45 | MP0009333_abnormal_splenocyte_physiolog | 1.23160072 |
| 46 | MP0005499_abnormal_olfactory_system | 1.21558049 |
| 47 | MP0005394_taste/olfaction_phenotype | 1.21558049 |
| 48 | MP0000372_irregular_coat_pigmentation | 1.21369298 |
| 49 | MP0001835_abnormal_antigen_presentation | 1.21139430 |
| 50 | MP0006035_abnormal_mitochondrial_morpho | 1.21044078 |
| 51 | MP0002735_abnormal_chemical_nociception | 1.20484196 |
| 52 | MP0003122_maternal_imprinting | 1.17057992 |
| 53 | MP0004885_abnormal_endolymph | 1.15521974 |
| 54 | MP0006036_abnormal_mitochondrial_physio | 1.12092458 |
| 55 | MP0002938_white_spotting | 1.11259284 |
| 56 | MP0002557_abnormal_social/conspecific_i | 1.11253987 |
| 57 | MP0005389_reproductive_system_phenotype | 1.09163417 |
| 58 | MP0000049_abnormal_middle_ear | 1.08934563 |
| 59 | MP0005084_abnormal_gallbladder_morpholo | 1.08707394 |
| 60 | MP0001764_abnormal_homeostasis | 1.07496998 |
| 61 | MP0001501_abnormal_sleep_pattern | 1.05175741 |
| 62 | MP0003121_genomic_imprinting | 1.03321166 |
| 63 | MP0004043_abnormal_pH_regulation | 1.02176846 |
| 64 | MP0005253_abnormal_eye_physiology | 1.01143095 |
| 65 | MP0005174_abnormal_tail_pigmentation | 1.00353268 |
| 66 | MP0002234_abnormal_pharynx_morphology | 0.98074216 |
| 67 | MP0001919_abnormal_reproductive_system | 0.97837954 |
| 68 | MP0001293_anophthalmia | 0.96820286 |
| 69 | MP0002210_abnormal_sex_determination | 0.95894827 |
| 70 | MP0003635_abnormal_synaptic_transmissio | 0.94295947 |
| 71 | MP0003878_abnormal_ear_physiology | 0.94240665 |
| 72 | MP0005377_hearing/vestibular/ear_phenot | 0.94240665 |
| 73 | MP0005670_abnormal_white_adipose | 0.92240901 |
| 74 | MP0002064_seizures | 0.90607079 |
| 75 | MP0002229_neurodegeneration | 0.90467946 |
| 76 | MP0001486_abnormal_startle_reflex | 0.89552754 |
| 77 | MP0002160_abnormal_reproductive_system | 0.89195224 |
| 78 | MP0002184_abnormal_innervation | 0.89018575 |
| 79 | MP0002063_abnormal_learning/memory/cond | 0.88123311 |
| 80 | MP0005535_abnormal_body_temperature | 0.87012628 |
| 81 | MP0001324_abnormal_eye_pigmentation | 0.81572459 |
| 82 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81349222 |
| 83 | MP0003806_abnormal_nucleotide_metabolis | 0.81259264 |
| 84 | MP0001502_abnormal_circadian_rhythm | 0.81190154 |
| 85 | MP0002277_abnormal_respiratory_mucosa | 0.80996013 |
| 86 | MP0001929_abnormal_gametogenesis | 0.80874265 |
| 87 | MP0003718_maternal_effect | 0.77778180 |
| 88 | MP0001485_abnormal_pinna_reflex | 0.75914013 |
| 89 | MP0008058_abnormal_DNA_repair | 0.75765721 |
| 90 | MP0003137_abnormal_impulse_conducting | 0.75256744 |
| 91 | MP0005410_abnormal_fertilization | 0.74679576 |
| 92 | MP0009785_altered_susceptibility_to | 0.74217119 |
| 93 | MP0005195_abnormal_posterior_eye | 0.74046305 |
| 94 | MP0008007_abnormal_cellular_replicative | 0.73296853 |
| 95 | MP0003283_abnormal_digestive_organ | 0.72828538 |
| 96 | MP0002138_abnormal_hepatobiliary_system | 0.72390587 |
| 97 | MP0002752_abnormal_somatic_nervous | 0.72381007 |
| 98 | MP0001119_abnormal_female_reproductive | 0.72021901 |
| 99 | MP0003698_abnormal_male_reproductive | 0.71921648 |
| 100 | MP0003938_abnormal_ear_development | 0.71523657 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.50511567 |
| 2 | Macrocytic anemia (HP:0001972) | 4.34336009 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.14104115 |
| 4 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.00295087 |
| 5 | Reticulocytopenia (HP:0001896) | 3.99079479 |
| 6 | Acute encephalopathy (HP:0006846) | 3.84836472 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.79552417 |
| 8 | Molar tooth sign on MRI (HP:0002419) | 3.76711503 |
| 9 | Abnormality of midbrain morphology (HP:0002418) | 3.76711503 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.66059066 |
| 11 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.54909063 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.54410262 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.51389112 |
| 14 | Increased CSF lactate (HP:0002490) | 3.41048841 |
| 15 | Abnormal hemoglobin (HP:0011902) | 3.38225200 |
| 16 | Pancreatic fibrosis (HP:0100732) | 3.35333692 |
| 17 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.35015135 |
| 18 | Abnormal number of erythroid precursors (HP:0012131) | 3.23252165 |
| 19 | Chronic hepatic failure (HP:0100626) | 3.14615520 |
| 20 | Central scotoma (HP:0000603) | 3.13954703 |
| 21 | Pancreatic cysts (HP:0001737) | 3.12915858 |
| 22 | Abnormal biliary tract physiology (HP:0012439) | 3.01011623 |
| 23 | Bile duct proliferation (HP:0001408) | 3.01011623 |
| 24 | Pallor (HP:0000980) | 3.00746252 |
| 25 | True hermaphroditism (HP:0010459) | 2.96527224 |
| 26 | Cerebral edema (HP:0002181) | 2.88700033 |
| 27 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.83844755 |
| 28 | Abnormality of alanine metabolism (HP:0010916) | 2.83844755 |
| 29 | Hyperalaninemia (HP:0003348) | 2.83844755 |
| 30 | Increased hepatocellular lipid droplets (HP:0006565) | 2.81361133 |
| 31 | Absent/shortened dynein arms (HP:0200106) | 2.79433664 |
| 32 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.79433664 |
| 33 | Optic disc pallor (HP:0000543) | 2.74867459 |
| 34 | Triphalangeal thumb (HP:0001199) | 2.64395304 |
| 35 | Abolished electroretinogram (ERG) (HP:0000550) | 2.55298170 |
| 36 | Lipid accumulation in hepatocytes (HP:0006561) | 2.52760695 |
| 37 | Abnormality of homocysteine metabolism (HP:0010919) | 2.42949192 |
| 38 | Homocystinuria (HP:0002156) | 2.42949192 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.42050936 |
| 40 | Dyschromatopsia (HP:0007641) | 2.39466828 |
| 41 | Hepatocellular necrosis (HP:0001404) | 2.38142435 |
| 42 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.37331406 |
| 43 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.37331406 |
| 44 | Increased intramyocellular lipid droplets (HP:0012240) | 2.33198813 |
| 45 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.31702086 |
| 46 | Increased serum lactate (HP:0002151) | 2.25119723 |
| 47 | Abnormal drinking behavior (HP:0030082) | 2.24603952 |
| 48 | Polydipsia (HP:0001959) | 2.24603952 |
| 49 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.23616350 |
| 50 | Pendular nystagmus (HP:0012043) | 2.23527713 |
| 51 | Stomatitis (HP:0010280) | 2.21989820 |
| 52 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.21916409 |
| 53 | Nephronophthisis (HP:0000090) | 2.20380864 |
| 54 | Constricted visual fields (HP:0001133) | 2.20164595 |
| 55 | Decreased central vision (HP:0007663) | 2.19569228 |
| 56 | Lactic acidosis (HP:0003128) | 2.19145288 |
| 57 | Supernumerary spleens (HP:0009799) | 2.15580515 |
| 58 | Attenuation of retinal blood vessels (HP:0007843) | 2.15354013 |
| 59 | Optic nerve coloboma (HP:0000588) | 2.14558286 |
| 60 | Anencephaly (HP:0002323) | 2.12688281 |
| 61 | Brushfield spots (HP:0001088) | 2.11960792 |
| 62 | Severe visual impairment (HP:0001141) | 2.11839086 |
| 63 | Meckel diverticulum (HP:0002245) | 2.11784370 |
| 64 | Hepatic necrosis (HP:0002605) | 2.11439099 |
| 65 | Leukodystrophy (HP:0002415) | 2.10157605 |
| 66 | Abnormality of the ileum (HP:0001549) | 2.10035940 |
| 67 | Medial flaring of the eyebrow (HP:0010747) | 2.09830242 |
| 68 | Lethargy (HP:0001254) | 2.08452050 |
| 69 | Stenosis of the external auditory canal (HP:0000402) | 2.07431163 |
| 70 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.06338162 |
| 71 | Cystic liver disease (HP:0006706) | 2.04339721 |
| 72 | Absent thumb (HP:0009777) | 2.01667808 |
| 73 | Microvesicular hepatic steatosis (HP:0001414) | 2.00161363 |
| 74 | Abnormality of the renal cortex (HP:0011035) | 1.99509989 |
| 75 | Congenital hepatic fibrosis (HP:0002612) | 1.96445728 |
| 76 | Depressed nasal ridge (HP:0000457) | 1.96252277 |
| 77 | Abnormality of the preputium (HP:0100587) | 1.93566648 |
| 78 | Exertional dyspnea (HP:0002875) | 1.92705306 |
| 79 | Abnormality of serum amino acid levels (HP:0003112) | 1.92480937 |
| 80 | Congenital, generalized hypertrichosis (HP:0004540) | 1.91410169 |
| 81 | Abnormality of the renal medulla (HP:0100957) | 1.88674298 |
| 82 | Sclerocornea (HP:0000647) | 1.86788790 |
| 83 | Increased muscle lipid content (HP:0009058) | 1.86563435 |
| 84 | Respiratory failure (HP:0002878) | 1.86548855 |
| 85 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.85661869 |
| 86 | Hyperglycinuria (HP:0003108) | 1.85414496 |
| 87 | IgG deficiency (HP:0004315) | 1.84385046 |
| 88 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.81163342 |
| 89 | Abnormality of urine glucose concentration (HP:0011016) | 1.80266522 |
| 90 | Glycosuria (HP:0003076) | 1.80266522 |
| 91 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.80244930 |
| 92 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.80244930 |
| 93 | Asplenia (HP:0001746) | 1.78702657 |
| 94 | Clubbing of toes (HP:0100760) | 1.78495141 |
| 95 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.78170330 |
| 96 | Abnormality of macular pigmentation (HP:0008002) | 1.77361507 |
| 97 | Keratoconus (HP:0000563) | 1.77101057 |
| 98 | Increased corneal curvature (HP:0100692) | 1.77101057 |
| 99 | Scotoma (HP:0000575) | 1.74440558 |
| 100 | Myokymia (HP:0002411) | 1.74347018 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PINK1 | 3.68388562 |
| 2 | MAP4K2 | 3.00692729 |
| 3 | CDK19 | 2.73997773 |
| 4 | ADRBK2 | 2.51228375 |
| 5 | NUAK1 | 2.46230864 |
| 6 | TLK1 | 2.38145157 |
| 7 | ZAK | 2.30885247 |
| 8 | TIE1 | 2.15982091 |
| 9 | BCKDK | 2.11225473 |
| 10 | GRK1 | 2.04582096 |
| 11 | DAPK2 | 1.95765713 |
| 12 | TEC | 1.95348708 |
| 13 | TRIM28 | 1.95205887 |
| 14 | KDR | 1.94123655 |
| 15 | WNK3 | 1.88113936 |
| 16 | MAP3K12 | 1.82559663 |
| 17 | NME2 | 1.80043144 |
| 18 | DYRK2 | 1.79899792 |
| 19 | CAMKK2 | 1.75997919 |
| 20 | TNK2 | 1.70171838 |
| 21 | WNK4 | 1.61335772 |
| 22 | MAP2K6 | 1.55052833 |
| 23 | LIMK1 | 1.53568858 |
| 24 | MAP3K11 | 1.42505100 |
| 25 | VRK1 | 1.38954624 |
| 26 | TXK | 1.38051666 |
| 27 | FRK | 1.37270017 |
| 28 | VRK2 | 1.31659553 |
| 29 | RPS6KB2 | 1.31080925 |
| 30 | INSRR | 1.22299209 |
| 31 | BMPR1B | 1.21468382 |
| 32 | MINK1 | 1.21297311 |
| 33 | TAOK3 | 1.20495863 |
| 34 | DAPK1 | 1.20341905 |
| 35 | OXSR1 | 1.16657813 |
| 36 | CSF1R | 1.16000960 |
| 37 | MAP4K1 | 1.11446972 |
| 38 | STK16 | 1.10890435 |
| 39 | ITK | 1.09264035 |
| 40 | PLK4 | 1.03131513 |
| 41 | KIT | 1.01930539 |
| 42 | CDC7 | 1.01488575 |
| 43 | DAPK3 | 0.99325883 |
| 44 | CAMKK1 | 0.97923516 |
| 45 | CDK8 | 0.97426827 |
| 46 | BUB1 | 0.94618667 |
| 47 | STK39 | 0.94006254 |
| 48 | MAPK13 | 0.93756783 |
| 49 | ACVR1B | 0.93186517 |
| 50 | CSNK1G2 | 0.92032905 |
| 51 | FES | 0.90158312 |
| 52 | NTRK3 | 0.86015743 |
| 53 | CSNK1G3 | 0.85229699 |
| 54 | EPHA4 | 0.82058811 |
| 55 | IKBKB | 0.81220861 |
| 56 | PASK | 0.76785261 |
| 57 | PRKCG | 0.75875550 |
| 58 | PHKG1 | 0.75808383 |
| 59 | PHKG2 | 0.75808383 |
| 60 | ADRBK1 | 0.75722067 |
| 61 | RPS6KA6 | 0.73799405 |
| 62 | CASK | 0.73472731 |
| 63 | SYK | 0.73441780 |
| 64 | PRKCQ | 0.71556457 |
| 65 | MKNK1 | 0.70045661 |
| 66 | TAF1 | 0.68779426 |
| 67 | MST4 | 0.66158720 |
| 68 | PAK6 | 0.65849781 |
| 69 | CAMK1 | 0.64664981 |
| 70 | CSNK1G1 | 0.63125394 |
| 71 | RPS6KL1 | 0.59869376 |
| 72 | RPS6KC1 | 0.59869376 |
| 73 | CDK3 | 0.58156529 |
| 74 | RPS6KB1 | 0.57522787 |
| 75 | CSNK2A2 | 0.57088417 |
| 76 | PRKCE | 0.56895375 |
| 77 | CAMK2A | 0.56344259 |
| 78 | RPS6KA5 | 0.55104505 |
| 79 | BTK | 0.55006683 |
| 80 | TYRO3 | 0.51823329 |
| 81 | PIK3CA | 0.51254208 |
| 82 | MAP2K7 | 0.50108278 |
| 83 | PRKCH | 0.49883074 |
| 84 | ILK | 0.49192601 |
| 85 | CSNK1A1L | 0.48601960 |
| 86 | MAP3K5 | 0.47693560 |
| 87 | PRKG2 | 0.46894048 |
| 88 | PRKG1 | 0.46736245 |
| 89 | TGFBR1 | 0.46695255 |
| 90 | MAPKAPK5 | 0.45818498 |
| 91 | LRRK2 | 0.45668473 |
| 92 | RPS6KA4 | 0.45611274 |
| 93 | NTRK2 | 0.44632942 |
| 94 | PRKACA | 0.44210527 |
| 95 | ABL2 | 0.43609357 |
| 96 | PIK3CG | 0.43192759 |
| 97 | NME1 | 0.42569765 |
| 98 | CSNK1A1 | 0.42180036 |
| 99 | OBSCN | 0.41603191 |
| 100 | LCK | 0.41271429 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.61799420 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.10364396 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.43551512 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 2.65372150 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.54376927 |
| 6 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.52984371 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.31947792 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.21384941 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.14294572 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.13804583 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.11068992 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.06904489 |
| 13 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.06281233 |
| 14 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.98149864 |
| 15 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.97507950 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.96273318 |
| 17 | Phototransduction_Homo sapiens_hsa04744 | 1.95910726 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.95073348 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.89779126 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.87178185 |
| 21 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.70860539 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.63314592 |
| 23 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.43087418 |
| 24 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.41089336 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.40804071 |
| 26 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.35721956 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.35140076 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.33329209 |
| 29 | Peroxisome_Homo sapiens_hsa04146 | 1.29123662 |
| 30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.23748380 |
| 31 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.22684112 |
| 32 | Basal transcription factors_Homo sapiens_hsa03022 | 1.21791901 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.18713192 |
| 34 | Homologous recombination_Homo sapiens_hsa03440 | 1.13757870 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13383204 |
| 36 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.07125630 |
| 37 | Nicotine addiction_Homo sapiens_hsa05033 | 1.06752361 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.04049886 |
| 39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.02846241 |
| 40 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.02435352 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97838207 |
| 42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.94869279 |
| 43 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.93460804 |
| 44 | Purine metabolism_Homo sapiens_hsa00230 | 0.89522614 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.87331679 |
| 46 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.83068940 |
| 47 | Retinol metabolism_Homo sapiens_hsa00830 | 0.79686955 |
| 48 | RNA transport_Homo sapiens_hsa03013 | 0.78370196 |
| 49 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.77976806 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.77438182 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.76791949 |
| 52 | Sulfur relay system_Homo sapiens_hsa04122 | 0.75730586 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.73026439 |
| 54 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.68013920 |
| 55 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.66560026 |
| 56 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.66503718 |
| 57 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.65712646 |
| 58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.64275013 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.63811563 |
| 60 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63132011 |
| 61 | Taste transduction_Homo sapiens_hsa04742 | 0.62478356 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62145340 |
| 63 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.56672411 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56628661 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.55654497 |
| 66 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.55519860 |
| 67 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.55496275 |
| 68 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.53576072 |
| 69 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.53189307 |
| 70 | Morphine addiction_Homo sapiens_hsa05032 | 0.52375450 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52081279 |
| 72 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.49669257 |
| 73 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49358650 |
| 74 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48229452 |
| 75 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.47818099 |
| 76 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.46005153 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.40438986 |
| 78 | Mismatch repair_Homo sapiens_hsa03430 | 0.39755605 |
| 79 | GABAergic synapse_Homo sapiens_hsa04727 | 0.38943974 |
| 80 | Salivary secretion_Homo sapiens_hsa04970 | 0.38911744 |
| 81 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.36357750 |
| 82 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.34870680 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.34620765 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.33062326 |
| 85 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.32859240 |
| 86 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.32605323 |
| 87 | Circadian entrainment_Homo sapiens_hsa04713 | 0.29889004 |
| 88 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.29323573 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.27554204 |
| 90 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27317409 |
| 91 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27267044 |
| 92 | Spliceosome_Homo sapiens_hsa03040 | 0.26461647 |
| 93 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.25834001 |
| 94 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24311276 |
| 95 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.24204484 |
| 96 | Insulin secretion_Homo sapiens_hsa04911 | 0.23735818 |
| 97 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.22434116 |
| 98 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.21492340 |
| 99 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.18395419 |
| 100 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.17885674 |

