RPS7P6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of cytosolic calcium ion concentration (GO:0051481)6.70495845
2viral transcription (GO:0019083)6.30248156
3ribosomal small subunit biogenesis (GO:0042274)6.29824915
4translational termination (GO:0006415)6.03768169
5negative regulation of cAMP-mediated signaling (GO:0043951)5.96180863
6opioid receptor signaling pathway (GO:0038003)5.84515326
7ribosomal small subunit assembly (GO:0000028)5.83589945
8maturation of SSU-rRNA (GO:0030490)5.40761792
9behavioral response to ethanol (GO:0048149)5.39297303
10translational elongation (GO:0006414)5.20906622
11pyrimidine deoxyribonucleotide catabolic process (GO:0009223)5.14563094
12SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.08224777
13cotranslational protein targeting to membrane (GO:0006613)5.00931139
14cell proliferation in forebrain (GO:0021846)4.99811923
15protein targeting to ER (GO:0045047)4.96425804
16ether lipid metabolic process (GO:0046485)4.95550919
17establishment of protein localization to endoplasmic reticulum (GO:0072599)4.82084040
18protein localization to endoplasmic reticulum (GO:0070972)4.77132037
19cellular protein complex disassembly (GO:0043624)4.69093279
20viral life cycle (GO:0019058)4.61028191
21regulation of translational termination (GO:0006449)4.50429152
22nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.48396832
23pyrimidine nucleotide catabolic process (GO:0006244)4.46919332
24adult feeding behavior (GO:0008343)4.29203049
25nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.13963737
26resolution of meiotic recombination intermediates (GO:0000712)4.12335088
27regulation of acrosome reaction (GO:0060046)4.09159671
28protein complex disassembly (GO:0043241)4.08804378
29macromolecular complex disassembly (GO:0032984)3.97802705
30mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.91495917
31mitochondrial respiratory chain complex I assembly (GO:0032981)3.91495917
32NADH dehydrogenase complex assembly (GO:0010257)3.91495917
33protein complex biogenesis (GO:0070271)3.84489101
34translational initiation (GO:0006413)3.82467377
35pattern specification involved in kidney development (GO:0061004)3.80543320
36mitochondrial respiratory chain complex assembly (GO:0033108)3.71081757
37pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.67655017
38ATP synthesis coupled proton transport (GO:0015986)3.67133736
39energy coupled proton transport, down electrochemical gradient (GO:0015985)3.67133736
40ncRNA catabolic process (GO:0034661)3.64610127
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.62296707
42adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.60945202
43positive regulation of cAMP-mediated signaling (GO:0043950)3.59602731
44piRNA metabolic process (GO:0034587)3.55547723
45negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.50541075
46glycerophospholipid catabolic process (GO:0046475)3.47187027
47ribosomal large subunit biogenesis (GO:0042273)3.46935812
48arginine catabolic process (GO:0006527)3.42864314
49translation (GO:0006412)3.39013600
50nuclear-transcribed mRNA catabolic process (GO:0000956)3.38372509
51mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.34088647
52protein neddylation (GO:0045116)3.30755452
53DNA replication-dependent nucleosome assembly (GO:0006335)3.25135155
54DNA replication-dependent nucleosome organization (GO:0034723)3.25135155
55exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.23219770
56cellular component biogenesis (GO:0044085)3.22055027
57protein targeting to membrane (GO:0006612)3.21865725
58base-excision repair, AP site formation (GO:0006285)3.21262252
59replication fork processing (GO:0031297)3.19276117
60mRNA catabolic process (GO:0006402)3.18734218
61ribonucleoprotein complex biogenesis (GO:0022613)3.16808122
62chaperone-mediated protein transport (GO:0072321)3.12816208
63behavioral response to nicotine (GO:0035095)3.07340057
64mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.03042892
65epithelial cilium movement (GO:0003351)3.02000479
66negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.01841284
67epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.00838419
68water-soluble vitamin biosynthetic process (GO:0042364)3.00769742
69pyrimidine dimer repair (GO:0006290)2.98549310
70regulation of cilium movement (GO:0003352)2.91318824
71myoblast migration (GO:0051451)2.90740650
72RNA catabolic process (GO:0006401)2.88557324
73kinetochore assembly (GO:0051382)2.86740731
74spermatid development (GO:0007286)2.86622098
75GTP biosynthetic process (GO:0006183)2.84973469
76auditory receptor cell differentiation (GO:0042491)2.84949457
77glycerol ether metabolic process (GO:0006662)2.84894937
78nephron tubule morphogenesis (GO:0072078)2.84293309
79nephron epithelium morphogenesis (GO:0072088)2.84293309
80respiratory electron transport chain (GO:0022904)2.81486791
81kinetochore organization (GO:0051383)2.79682079
82telencephalon development (GO:0021537)2.78922142
83electron transport chain (GO:0022900)2.78621084
84DNA deamination (GO:0045006)2.78616261
85deoxyribonucleotide catabolic process (GO:0009264)2.76558159
86neuron fate determination (GO:0048664)2.70966663
87regulation of protein glycosylation (GO:0060049)2.70361225
88heterochromatin organization (GO:0070828)2.68328582
89tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.68063996
90RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.68063996
91outer ear morphogenesis (GO:0042473)2.67861273
92preassembly of GPI anchor in ER membrane (GO:0016254)2.67451309
93neuron projection extension involved in neuron projection guidance (GO:1902284)2.66522142
94axon extension involved in axon guidance (GO:0048846)2.66522142
95regulation of microtubule-based movement (GO:0060632)2.63995413
96termination of RNA polymerase III transcription (GO:0006386)2.63991180
97transcription elongation from RNA polymerase III promoter (GO:0006385)2.63991180
98ether metabolic process (GO:0018904)2.63133605
99pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.61943745
100chromatin remodeling at centromere (GO:0031055)2.61355249

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat5.07252709
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.60167561
3VDR_22108803_ChIP-Seq_LS180_Human3.34676602
4EZH2_22144423_ChIP-Seq_EOC_Human3.20855179
5SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.98881065
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.50595505
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.38244835
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.35523941
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.32939341
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.24837700
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.19139959
12MYC_18555785_ChIP-Seq_MESCs_Mouse2.10482782
13EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human2.06105626
14IRF1_19129219_ChIP-ChIP_H3396_Human2.00463518
15ZNF274_21170338_ChIP-Seq_K562_Hela1.84437568
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.69118384
17CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.64481878
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.60770200
19EED_16625203_ChIP-ChIP_MESCs_Mouse1.60072110
20TTF2_22483619_ChIP-Seq_HELA_Human1.58623959
21MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58599247
22EZH2_27294783_Chip-Seq_ESCs_Mouse1.58127120
23POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.57122711
24TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57122711
25NANOG_20526341_ChIP-Seq_ESCs_Human1.55592891
26MYC_18940864_ChIP-ChIP_HL60_Human1.54279243
27RXR_22108803_ChIP-Seq_LS180_Human1.52825966
28MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.51020607
29GATA3_21878914_ChIP-Seq_MCF-7_Human1.50810906
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.50705401
31JARID2_20064375_ChIP-Seq_MESCs_Mouse1.50131552
32GABP_19822575_ChIP-Seq_HepG2_Human1.46467024
33DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.42784000
34PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.42613237
35TP63_19390658_ChIP-ChIP_HaCaT_Human1.41883552
36SUZ12_27294783_Chip-Seq_ESCs_Mouse1.36137780
37MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.36018771
38ERA_21632823_ChIP-Seq_H3396_Human1.36014429
39SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.33366585
40TP53_20018659_ChIP-ChIP_R1E_Mouse1.32323468
41SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.31727174
42FOXH1_21741376_ChIP-Seq_EPCs_Human1.30574024
43MYC_18358816_ChIP-ChIP_MESCs_Mouse1.27889551
44YY1_21170310_ChIP-Seq_MESCs_Mouse1.27710647
45BMI1_23680149_ChIP-Seq_NPCS_Mouse1.24775932
46CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.24473958
47JARID2_20075857_ChIP-Seq_MESCs_Mouse1.24206699
48SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.23871130
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22773542
50FOXP3_21729870_ChIP-Seq_TREG_Human1.22358138
51POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.21912163
52TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.21297905
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.20255832
54CTCF_20526341_ChIP-Seq_ESCs_Human1.20107816
55EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.19546550
56CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.19414915
57PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.19105293
58CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.18912418
59FUS_26573619_Chip-Seq_HEK293_Human1.15401355
60CBP_20019798_ChIP-Seq_JUKART_Human1.15033106
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15033106
62RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.14754697
63SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.14350037
64PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.14097998
65MYC_19079543_ChIP-ChIP_MESCs_Mouse1.13585309
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.13306544
67FLI1_27457419_Chip-Seq_LIVER_Mouse1.12539080
68IGF1R_20145208_ChIP-Seq_DFB_Human1.11162207
69CTBP1_25329375_ChIP-Seq_LNCAP_Human1.10481576
70RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.10467333
71EZH2_18974828_ChIP-Seq_MESCs_Mouse1.10259662
72RNF2_18974828_ChIP-Seq_MESCs_Mouse1.10259662
73TP53_22573176_ChIP-Seq_HFKS_Human1.09947951
74RNF2_27304074_Chip-Seq_ESCs_Mouse1.09249512
75TAF2_19829295_ChIP-Seq_ESCs_Human1.08969021
76SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.08846759
77KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08282408
78REST_21632747_ChIP-Seq_MESCs_Mouse1.07539910
79THAP11_20581084_ChIP-Seq_MESCs_Mouse1.06913996
80CTCF_18555785_ChIP-Seq_MESCs_Mouse1.06810341
81RNF2_27304074_Chip-Seq_NSC_Mouse1.06461500
82SRF_21415370_ChIP-Seq_HL-1_Mouse1.04454399
83PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.04030342
84NANOG_19829295_ChIP-Seq_ESCs_Human1.03830210
85SOX2_19829295_ChIP-Seq_ESCs_Human1.03830210
86CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.03149350
87E2F1_18555785_ChIP-Seq_MESCs_Mouse1.02726086
88VDR_23849224_ChIP-Seq_CD4+_Human1.02494122
89PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.01190802
90TDRD3_21172665_ChIP-Seq_MCF-7_Human1.00387721
91NCOR_22424771_ChIP-Seq_293T_Human1.00213735
92FOXH1_21741376_ChIP-Seq_ESCs_Human0.99462735
93XRN2_22483619_ChIP-Seq_HELA_Human0.98190558
94GATA3_21867929_ChIP-Seq_TH1_Mouse0.98056159
95YY1_22570637_ChIP-Seq_MALME-3M_Human0.97205071
96REST_18959480_ChIP-ChIP_MESCs_Mouse0.96752498
97KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.96005031
98SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.95338435
99BCAT_22108803_ChIP-Seq_LS180_Human0.94519069
100SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.94429035

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.61734156
2MP0009379_abnormal_foot_pigmentation4.45945471
3MP0008789_abnormal_olfactory_epithelium3.03813646
4MP0001968_abnormal_touch/_nociception2.79009966
5MP0000678_abnormal_parathyroid_gland2.61913217
6MP0002876_abnormal_thyroid_physiology2.55883280
7MP0010030_abnormal_orbit_morphology2.51995008
8MP0000049_abnormal_middle_ear2.34346255
9MP0009780_abnormal_chondrocyte_physiolo2.28049741
10MP0003787_abnormal_imprinting2.25427225
11MP0003121_genomic_imprinting2.17099983
12MP0005360_urolithiasis2.14473229
13MP0003122_maternal_imprinting2.13651918
14MP0005499_abnormal_olfactory_system2.11346437
15MP0005394_taste/olfaction_phenotype2.11346437
16MP0009278_abnormal_bone_marrow1.99944106
17MP0002249_abnormal_larynx_morphology1.94373403
18MP0009053_abnormal_anal_canal1.93781518
19MP0004142_abnormal_muscle_tone1.88844837
20MP0003646_muscle_fatigue1.85676134
21MP0003123_paternal_imprinting1.85250726
22MP0005551_abnormal_eye_electrophysiolog1.82084831
23MP0008775_abnormal_heart_ventricle1.80436379
24MP0001293_anophthalmia1.80311303
25MP0003136_yellow_coat_color1.74834091
26MP0004147_increased_porphyrin_level1.72827874
27MP0008877_abnormal_DNA_methylation1.70570874
28MP0005646_abnormal_pituitary_gland1.69709988
29MP0002272_abnormal_nervous_system1.65143221
30MP0003937_abnormal_limbs/digits/tail_de1.59650756
31MP0000778_abnormal_nervous_system1.57436247
32MP0002938_white_spotting1.55276848
33MP0001485_abnormal_pinna_reflex1.48552377
34MP0009745_abnormal_behavioral_response1.40849882
35MP0003938_abnormal_ear_development1.36843936
36MP0002733_abnormal_thermal_nociception1.36734987
37MP0002837_dystrophic_cardiac_calcinosis1.34411141
38MP0000566_synostosis1.33554395
39MP0005195_abnormal_posterior_eye1.32621159
40MP0005084_abnormal_gallbladder_morpholo1.31985864
41MP0005670_abnormal_white_adipose1.31449757
42MP0000631_abnormal_neuroendocrine_gland1.31410942
43MP0006276_abnormal_autonomic_nervous1.29642025
44MP0005645_abnormal_hypothalamus_physiol1.26919532
45MP0002653_abnormal_ependyma_morphology1.26463493
46MP0003880_abnormal_central_pattern1.23239152
47MP0002163_abnormal_gland_morphology1.20789206
48MP0002102_abnormal_ear_morphology1.19873023
49MP0009764_decreased_sensitivity_to1.15686364
50MP0000681_abnormal_thyroid_gland1.14274608
51MP0006035_abnormal_mitochondrial_morpho1.13759063
52MP0003879_abnormal_hair_cell1.12437455
53MP0006072_abnormal_retinal_apoptosis1.09683460
54MP0000026_abnormal_inner_ear1.07031548
55MP0002736_abnormal_nociception_after1.07019025
56MP0003942_abnormal_urinary_system1.06660645
57MP0001963_abnormal_hearing_physiology1.04824529
58MP0009046_muscle_twitch1.04554670
59MP0002095_abnormal_skin_pigmentation1.03862823
60MP0005377_hearing/vestibular/ear_phenot1.03678632
61MP0003878_abnormal_ear_physiology1.03678632
62MP0003186_abnormal_redox_activity0.98866360
63MP0003959_abnormal_lean_body0.97735163
64MP0002752_abnormal_somatic_nervous0.96748203
65MP0008058_abnormal_DNA_repair0.96139929
66MP0005503_abnormal_tendon_morphology0.95780588
67MP0001970_abnormal_pain_threshold0.95244972
68MP0002557_abnormal_social/conspecific_i0.95168703
69MP0005408_hypopigmentation0.93466194
70MP0003936_abnormal_reproductive_system0.93161985
71MP0004133_heterotaxia0.92222573
72MP0002233_abnormal_nose_morphology0.90836954
73MP0001664_abnormal_digestion0.89328095
74MP0009250_abnormal_appendicular_skeleto0.87559920
75MP0005389_reproductive_system_phenotype0.86116134
76MP0000516_abnormal_urinary_system0.85360567
77MP0005367_renal/urinary_system_phenotyp0.85360567
78MP0005083_abnormal_biliary_tract0.84612188
79MP0009333_abnormal_splenocyte_physiolog0.83525651
80MP0002210_abnormal_sex_determination0.81940358
81MP0001324_abnormal_eye_pigmentation0.81696013
82MP0004742_abnormal_vestibular_system0.81311730
83MP0003638_abnormal_response/metabolism_0.81245828
84MP0003567_abnormal_fetal_cardiomyocyte0.78185334
85MP0008872_abnormal_physiological_respon0.77873660
86MP0009765_abnormal_xenobiotic_induced0.76881358
87MP0001440_abnormal_grooming_behavior0.75786414
88MP0002160_abnormal_reproductive_system0.75374331
89MP0000230_abnormal_systemic_arterial0.75221181
90MP0003755_abnormal_palate_morphology0.74883508
91MP0003633_abnormal_nervous_system0.73393029
92MP0001286_abnormal_eye_development0.71522075
93MP0003635_abnormal_synaptic_transmissio0.68967717
94MP0004858_abnormal_nervous_system0.68958889
95MP0002063_abnormal_learning/memory/cond0.68714685
96MP0001529_abnormal_vocalization0.67976943
97MP0000534_abnormal_ureter_morphology0.67580137
98MP0001501_abnormal_sleep_pattern0.67429407
99MP0001929_abnormal_gametogenesis0.67353987
100MP0004859_abnormal_synaptic_plasticity0.65989102

Predicted human phenotypes

RankGene SetZ-score
1Thyroid-stimulating hormone excess (HP:0002925)6.83405623
2Reticulocytopenia (HP:0001896)5.01990872
3Abnormality of the aortic arch (HP:0012303)4.37225242
4Abnormality of cells of the erythroid lineage (HP:0012130)4.11889014
5Acute necrotizing encephalopathy (HP:0006965)3.70371140
6Type II lissencephaly (HP:0007260)3.51797859
7Volvulus (HP:0002580)3.31662484
8Poor head control (HP:0002421)3.30132082
9Macrocytic anemia (HP:0001972)3.20684148
10Intestinal atresia (HP:0011100)3.19814203
11Abnormal number of erythroid precursors (HP:0012131)3.19534841
12Abnormal mitochondria in muscle tissue (HP:0008316)3.15385974
13Stenosis of the external auditory canal (HP:0000402)3.13089694
14Acute encephalopathy (HP:0006846)3.11947987
15Molar tooth sign on MRI (HP:0002419)2.96603899
16Abnormality of midbrain morphology (HP:0002418)2.96603899
17Focal motor seizures (HP:0011153)2.96459014
18Optic nerve hypoplasia (HP:0000609)2.90574594
19Broad alveolar ridges (HP:0000187)2.89876248
20Adrenal hypoplasia (HP:0000835)2.89312433
21Cerebellar dysplasia (HP:0007033)2.89042300
22Tubular atrophy (HP:0000092)2.88350485
23Mitochondrial inheritance (HP:0001427)2.87538152
24Progressive macrocephaly (HP:0004481)2.81911057
25Pancreatic fibrosis (HP:0100732)2.80929286
26Pendular nystagmus (HP:0012043)2.80124031
27Hyperglycinemia (HP:0002154)2.70918486
28Nephronophthisis (HP:0000090)2.70562439
29Abnormal number of incisors (HP:0011064)2.70324789
30Colon cancer (HP:0003003)2.67966559
31Abnormality of the ileum (HP:0001549)2.63191564
32Medial flaring of the eyebrow (HP:0010747)2.61967256
33Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.61965225
34Agitation (HP:0000713)2.61254491
35Congenital ichthyosiform erythroderma (HP:0007431)2.59554089
36Increased CSF lactate (HP:0002490)2.58541733
37True hermaphroditism (HP:0010459)2.56949847
38Sclerocornea (HP:0000647)2.55400391
39Septo-optic dysplasia (HP:0100842)2.54691723
40Oligodontia (HP:0000677)2.45138977
41Aplasia/Hypoplasia of the tongue (HP:0010295)2.45059824
42Absent rod-and cone-mediated responses on ERG (HP:0007688)2.36382879
43Pancreatic cysts (HP:0001737)2.34741813
44Aplasia/Hypoplasia of the sacrum (HP:0008517)2.31560025
45Severe visual impairment (HP:0001141)2.27025814
46Anophthalmia (HP:0000528)2.26185952
47Pallor (HP:0000980)2.25690775
48Pancreatic islet-cell hyperplasia (HP:0004510)2.23623987
49Lissencephaly (HP:0001339)2.21096696
50Dynein arm defect of respiratory motile cilia (HP:0012255)2.19008662
51Absent/shortened dynein arms (HP:0200106)2.19008662
52Impulsivity (HP:0100710)2.18090774
53Gait imbalance (HP:0002141)2.16586138
54Congenital primary aphakia (HP:0007707)2.16530084
55Nephrogenic diabetes insipidus (HP:0009806)2.16465412
56Anencephaly (HP:0002323)2.15649997
57Abnormal respiratory motile cilium morphology (HP:0005938)2.13991976
58Abnormal respiratory epithelium morphology (HP:0012253)2.13991976
59Abnormal rod and cone electroretinograms (HP:0008323)2.12918922
60Hyperthyroidism (HP:0000836)2.12399879
61Poikiloderma (HP:0001029)2.11051705
62Thickened helices (HP:0000391)2.10486854
63Maternal diabetes (HP:0009800)2.08654731
64Postaxial foot polydactyly (HP:0001830)2.07969703
65Cerebral edema (HP:0002181)2.07344664
66Entropion (HP:0000621)2.07208418
67Severe muscular hypotonia (HP:0006829)2.06251847
68Abnormality of the renal medulla (HP:0100957)2.05888928
69Absent thumb (HP:0009777)2.03013810
70Supernumerary spleens (HP:0009799)2.01787396
71Methylmalonic aciduria (HP:0012120)1.99298682
72Hepatocellular necrosis (HP:0001404)1.97572391
73Rib fusion (HP:0000902)1.96506256
74Optic disc pallor (HP:0000543)1.93604659
75High anterior hairline (HP:0009890)1.93356687
76Holoprosencephaly (HP:0001360)1.92955037
77Microglossia (HP:0000171)1.90999433
78Microretrognathia (HP:0000308)1.88992894
79Renal dysplasia (HP:0000110)1.88598824
80Oligodactyly (HP:0012165)1.85652155
81Depressed nasal ridge (HP:0000457)1.84529522
823-Methylglutaconic aciduria (HP:0003535)1.83522835
83Aplasia/Hypoplasia of the spleen (HP:0010451)1.82687454
84Myokymia (HP:0002411)1.82379321
85Partial duplication of thumb phalanx (HP:0009944)1.80615938
86Gastrointestinal atresia (HP:0002589)1.80084108
87Dandy-Walker malformation (HP:0001305)1.79762417
88Male pseudohermaphroditism (HP:0000037)1.79734682
89Abnormality of the incisor (HP:0000676)1.79543755
90Abnormality of glycine metabolism (HP:0010895)1.78770574
91Abnormality of serine family amino acid metabolism (HP:0010894)1.78770574
92Flat capital femoral epiphysis (HP:0003370)1.78298182
93Cerebellar hypoplasia (HP:0001321)1.77003802
94Mesangial abnormality (HP:0001966)1.76684081
95Large for gestational age (HP:0001520)1.74975265
96Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.74833768
97Abnormality of alanine metabolism (HP:0010916)1.74833768
98Hyperalaninemia (HP:0003348)1.74833768
99Vaginal atresia (HP:0000148)1.74574309
100Aplasia/Hypoplasia affecting the fundus (HP:0008057)1.74002117

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ADRBK26.49136205
2STK163.76106812
3NME23.50484861
4BCKDK2.74260399
5VRK22.57001033
6TYRO32.22864660
7MAP2K72.15045896
8TIE12.14720200
9FRK2.10710130
10NTRK21.93162851
11CDK191.91953979
12PRKCG1.74299591
13CDC71.72897810
14NUAK11.72372853
15PINK11.70442700
16DYRK21.68561254
17ADRBK11.67982602
18LIMK11.63867586
19ERN11.61908710
20GRK11.60818941
21PIK3CA1.53013851
22MAP3K111.36413843
23EPHA41.35517220
24MAP3K41.35170998
25ZAK1.32970246
26DYRK31.31520178
27PRKCI1.21253889
28CAMK11.19881604
29LRRK21.18850425
30ARAF1.16598982
31AURKA1.16517636
32PNCK1.15344760
33BRAF1.07896958
34CAMK1G1.06990337
35WNK41.06631852
36CAMK1D1.03713263
37CSNK1G30.98640455
38PRKCE0.95752220
39EPHB20.93743029
40AURKB0.92669370
41WNK30.90802553
42NME10.89203319
43CSNK1A1L0.87946539
44CSNK1G20.85821968
45VRK10.83924009
46MAPK130.83104769
47ABL20.80979922
48CSNK1G10.78150405
49STK390.77451832
50PIM20.75671192
51IRAK30.74549426
52BCR0.73899577
53CAMK40.73124359
54NEK10.69919318
55CSNK2A20.68969989
56DAPK30.68155391
57PDK20.67756795
58NEK20.66283404
59EPHA20.65389734
60MAP2K40.64998289
61TESK20.63291385
62CAMK2A0.62723401
63UHMK10.60906634
64PHKG20.60839446
65PHKG10.60839446
66MAPK150.60317119
67PRKACA0.58808021
68PLK20.58244262
69MAPKAPK50.57388453
70CAMKK20.56788232
71MARK30.54246605
72CHEK20.53320828
73MAP4K20.53222339
74TGFBR10.52223032
75MAP3K120.50389187
76PLK10.49997314
77CSNK1A10.49384263
78RPS6KA50.48653025
79DMPK0.48350306
80BRSK10.47686883
81GRK50.47159705
82MOS0.46524364
83SGK10.45813769
84KDR0.44916739
85GRK70.44503652
86TAF10.44200294
87PKN10.43527130
88PLK40.41861552
89CSNK2A10.40509746
90WEE10.40421004
91RPS6KA60.38882005
92ATR0.37273696
93INSRR0.36620078
94PRKCA0.35329435
95BUB10.35131968
96CSNK1E0.34507019
97PTK2B0.33879019
98TEC0.33853534
99ERBB20.32889019
100FGFR20.32834959

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.89091932
2Oxidative phosphorylation_Homo sapiens_hsa001903.48532055
3Sulfur relay system_Homo sapiens_hsa041223.01811248
4Parkinsons disease_Homo sapiens_hsa050122.85446289
5Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.57499862
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.37612036
7Huntingtons disease_Homo sapiens_hsa050162.32688675
8RNA polymerase_Homo sapiens_hsa030202.23436624
9Fanconi anemia pathway_Homo sapiens_hsa034602.17606051
10Cardiac muscle contraction_Homo sapiens_hsa042602.12260621
11Alzheimers disease_Homo sapiens_hsa050102.05172283
12Homologous recombination_Homo sapiens_hsa034402.02807962
13Cyanoamino acid metabolism_Homo sapiens_hsa004602.02667973
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.88546481
15Linoleic acid metabolism_Homo sapiens_hsa005911.84360158
16Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.71947814
17Basal cell carcinoma_Homo sapiens_hsa052171.68019620
18Base excision repair_Homo sapiens_hsa034101.67511630
19Protein export_Homo sapiens_hsa030601.65591018
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.65461864
21Pyrimidine metabolism_Homo sapiens_hsa002401.63902259
22Hedgehog signaling pathway_Homo sapiens_hsa043401.63091377
23Mismatch repair_Homo sapiens_hsa034301.59310852
24Nucleotide excision repair_Homo sapiens_hsa034201.59006707
25Proteasome_Homo sapiens_hsa030501.58829785
26Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.57301576
27Basal transcription factors_Homo sapiens_hsa030221.57107256
28Phototransduction_Homo sapiens_hsa047441.55981966
29Glycosaminoglycan degradation_Homo sapiens_hsa005311.55754398
30DNA replication_Homo sapiens_hsa030301.55135800
31alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.43650812
32Arachidonic acid metabolism_Homo sapiens_hsa005901.30977680
33RNA degradation_Homo sapiens_hsa030181.25541902
34Olfactory transduction_Homo sapiens_hsa047401.21170857
35Nicotine addiction_Homo sapiens_hsa050331.18448580
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.16369509
37Steroid hormone biosynthesis_Homo sapiens_hsa001401.12653747
38Butanoate metabolism_Homo sapiens_hsa006501.08396562
39Glutathione metabolism_Homo sapiens_hsa004801.06261067
40Morphine addiction_Homo sapiens_hsa050321.04742651
41Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02763037
42Purine metabolism_Homo sapiens_hsa002300.99120747
43Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.96454224
44Fat digestion and absorption_Homo sapiens_hsa049750.90865465
45Propanoate metabolism_Homo sapiens_hsa006400.90862410
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.90200537
47Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.86971055
48Dorso-ventral axis formation_Homo sapiens_hsa043200.86266023
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.84933657
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.84369576
51Metabolic pathways_Homo sapiens_hsa011000.81075324
52One carbon pool by folate_Homo sapiens_hsa006700.75151980
53Chemical carcinogenesis_Homo sapiens_hsa052040.74730700
54Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74054808
55Vitamin B6 metabolism_Homo sapiens_hsa007500.71018842
56Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.70201815
57Retinol metabolism_Homo sapiens_hsa008300.69626005
58Tryptophan metabolism_Homo sapiens_hsa003800.69467207
59Pyruvate metabolism_Homo sapiens_hsa006200.67731272
60RNA transport_Homo sapiens_hsa030130.67430211
61Ether lipid metabolism_Homo sapiens_hsa005650.66321406
62Fatty acid degradation_Homo sapiens_hsa000710.66213855
63Cysteine and methionine metabolism_Homo sapiens_hsa002700.64725032
64Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63254607
65Glycerolipid metabolism_Homo sapiens_hsa005610.63035869
66Primary bile acid biosynthesis_Homo sapiens_hsa001200.62976141
67Salivary secretion_Homo sapiens_hsa049700.62847228
68Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62167888
69Notch signaling pathway_Homo sapiens_hsa043300.61855882
70Nitrogen metabolism_Homo sapiens_hsa009100.61831523
71Caffeine metabolism_Homo sapiens_hsa002320.57931998
72Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57620614
73Peroxisome_Homo sapiens_hsa041460.57268530
74Sulfur metabolism_Homo sapiens_hsa009200.56951771
75Ovarian steroidogenesis_Homo sapiens_hsa049130.52910083
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52641508
77Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.52021038
78Folate biosynthesis_Homo sapiens_hsa007900.47985027
79Hippo signaling pathway_Homo sapiens_hsa043900.47607882
80Taste transduction_Homo sapiens_hsa047420.46531554
81beta-Alanine metabolism_Homo sapiens_hsa004100.41841470
82Drug metabolism - other enzymes_Homo sapiens_hsa009830.41653061
83Arginine and proline metabolism_Homo sapiens_hsa003300.38757330
84Fatty acid elongation_Homo sapiens_hsa000620.38231718
85Starch and sucrose metabolism_Homo sapiens_hsa005000.37622842
86Asthma_Homo sapiens_hsa053100.36999114
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.31727826
88Insulin secretion_Homo sapiens_hsa049110.30272408
89Pentose phosphate pathway_Homo sapiens_hsa000300.30138693
90Intestinal immune network for IgA production_Homo sapiens_hsa046720.29781628
91Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.29086952
92Maturity onset diabetes of the young_Homo sapiens_hsa049500.28991817
93GABAergic synapse_Homo sapiens_hsa047270.26037571
94Spliceosome_Homo sapiens_hsa030400.25299908
95Glutamatergic synapse_Homo sapiens_hsa047240.24723894
96Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.24614723
97Serotonergic synapse_Homo sapiens_hsa047260.22631102
98Tyrosine metabolism_Homo sapiens_hsa003500.22554700
99Mineral absorption_Homo sapiens_hsa049780.19382651
100mRNA surveillance pathway_Homo sapiens_hsa030150.19317500

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »