

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 8.65603640 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 8.61161567 |
| 3 | translational termination (GO:0006415) | 8.27501814 |
| 4 | maturation of SSU-rRNA (GO:0030490) | 8.17519298 |
| 5 | chaperone-mediated protein transport (GO:0072321) | 7.24185151 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 7.04726783 |
| 7 | translational elongation (GO:0006414) | 7.00417813 |
| 8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.84164347 |
| 9 | protein targeting to ER (GO:0045047) | 6.74611422 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 6.73575130 |
| 11 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.46236919 |
| 12 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.31438399 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 6.30524934 |
| 14 | cellular protein complex disassembly (GO:0043624) | 6.28801814 |
| 15 | viral life cycle (GO:0019058) | 6.23125766 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 5.80290324 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.80290324 |
| 18 | translational initiation (GO:0006413) | 5.47261231 |
| 19 | protein complex disassembly (GO:0043241) | 5.34195601 |
| 20 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.16614794 |
| 21 | activation of MAPKKK activity (GO:0000185) | 5.12555464 |
| 22 | macromolecular complex disassembly (GO:0032984) | 5.05385699 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.70252723 |
| 24 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.67816581 |
| 25 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.67816581 |
| 26 | NADH dehydrogenase complex assembly (GO:0010257) | 4.67816581 |
| 27 | behavioral response to nicotine (GO:0035095) | 4.63705482 |
| 28 | protein targeting to membrane (GO:0006612) | 4.55199710 |
| 29 | translation (GO:0006412) | 4.43061209 |
| 30 | protein complex biogenesis (GO:0070271) | 4.42522474 |
| 31 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.42471354 |
| 32 | DNA deamination (GO:0045006) | 4.32756097 |
| 33 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.28697898 |
| 34 | mRNA catabolic process (GO:0006402) | 4.19164687 |
| 35 | respiratory electron transport chain (GO:0022904) | 4.18571441 |
| 36 | protein neddylation (GO:0045116) | 4.16996047 |
| 37 | electron transport chain (GO:0022900) | 4.16868004 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.15808674 |
| 39 | rRNA transcription (GO:0009303) | 4.02237556 |
| 40 | cellular component biogenesis (GO:0044085) | 3.98561364 |
| 41 | ribosomal large subunit biogenesis (GO:0042273) | 3.96368758 |
| 42 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.96180630 |
| 43 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.92569559 |
| 44 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 3.91100900 |
| 45 | resolution of meiotic recombination intermediates (GO:0000712) | 3.89042521 |
| 46 | RNA catabolic process (GO:0006401) | 3.74209597 |
| 47 | pattern specification involved in kidney development (GO:0061004) | 3.68716859 |
| 48 | rRNA metabolic process (GO:0016072) | 3.61115274 |
| 49 | leukocyte aggregation (GO:0070486) | 3.59685587 |
| 50 | pseudouridine synthesis (GO:0001522) | 3.51872463 |
| 51 | ATP biosynthetic process (GO:0006754) | 3.46387172 |
| 52 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.45998752 |
| 53 | GTP biosynthetic process (GO:0006183) | 3.44768754 |
| 54 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.38064011 |
| 55 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.37403511 |
| 56 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.33381292 |
| 57 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.29207205 |
| 58 | rRNA processing (GO:0006364) | 3.28389625 |
| 59 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.23889123 |
| 60 | termination of RNA polymerase III transcription (GO:0006386) | 3.23889123 |
| 61 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.21854598 |
| 62 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.15411280 |
| 63 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.14212368 |
| 64 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.14212368 |
| 65 | protein targeting (GO:0006605) | 3.12960098 |
| 66 | establishment of protein localization to membrane (GO:0090150) | 3.08346265 |
| 67 | myoblast migration (GO:0051451) | 3.06657560 |
| 68 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.04344914 |
| 69 | intracellular protein transmembrane import (GO:0044743) | 3.01646796 |
| 70 | peptidyl-histidine modification (GO:0018202) | 2.97283749 |
| 71 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 2.97214975 |
| 72 | cell proliferation in forebrain (GO:0021846) | 2.96701773 |
| 73 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.95481560 |
| 74 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.95481560 |
| 75 | meiotic chromosome segregation (GO:0045132) | 2.93280577 |
| 76 | UTP biosynthetic process (GO:0006228) | 2.91964770 |
| 77 | establishment of protein localization to organelle (GO:0072594) | 2.89073430 |
| 78 | segment specification (GO:0007379) | 2.88391226 |
| 79 | protein targeting to mitochondrion (GO:0006626) | 2.87774424 |
| 80 | glycoprotein catabolic process (GO:0006516) | 2.81515920 |
| 81 | hydrogen ion transmembrane transport (GO:1902600) | 2.81286948 |
| 82 | establishment of protein localization to mitochondrion (GO:0072655) | 2.75965528 |
| 83 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.75570244 |
| 84 | positive regulation of vascular permeability (GO:0043117) | 2.74559160 |
| 85 | nonmotile primary cilium assembly (GO:0035058) | 2.73611122 |
| 86 | UTP metabolic process (GO:0046051) | 2.72712147 |
| 87 | protein-cofactor linkage (GO:0018065) | 2.72169743 |
| 88 | ubiquinone biosynthetic process (GO:0006744) | 2.70949978 |
| 89 | ncRNA 3-end processing (GO:0043628) | 2.66651967 |
| 90 | iron-sulfur cluster assembly (GO:0016226) | 2.66076983 |
| 91 | metallo-sulfur cluster assembly (GO:0031163) | 2.66076983 |
| 92 | cardiovascular system development (GO:0072358) | 2.65317068 |
| 93 | reciprocal DNA recombination (GO:0035825) | 2.64785425 |
| 94 | reciprocal meiotic recombination (GO:0007131) | 2.64785425 |
| 95 | inner mitochondrial membrane organization (GO:0007007) | 2.63191442 |
| 96 | epithelial cilium movement (GO:0003351) | 2.62404465 |
| 97 | male meiosis I (GO:0007141) | 2.61217053 |
| 98 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.61050324 |
| 99 | spinal cord development (GO:0021510) | 2.60472555 |
| 100 | positive regulation of defense response to virus by host (GO:0002230) | 2.59549240 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.19130742 |
| 2 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.51397969 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.35162731 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.28381843 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.99593847 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.97115027 |
| 7 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.88332038 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.81150439 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.69029122 |
| 10 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.49811010 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.34502308 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.25200397 |
| 13 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.23796503 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.19796576 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.19223788 |
| 16 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.08354538 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.05595661 |
| 18 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.01075038 |
| 19 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.97026342 |
| 20 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.83230044 |
| 21 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.82214444 |
| 22 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.81465668 |
| 23 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.79555753 |
| 24 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.79208147 |
| 25 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.77990584 |
| 26 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.69810576 |
| 27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.61696032 |
| 28 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.59510538 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59470129 |
| 30 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.56103887 |
| 31 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.54660654 |
| 32 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.52395070 |
| 33 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.51765378 |
| 34 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.47471578 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.46249577 |
| 36 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.45699080 |
| 37 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45126887 |
| 38 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.44674549 |
| 39 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.40302501 |
| 40 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.38710565 |
| 41 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.38692251 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.38244351 |
| 43 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.37744359 |
| 44 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.35872593 |
| 45 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.34919449 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34336675 |
| 47 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.33002124 |
| 48 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.31136298 |
| 49 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.28119089 |
| 50 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.27916719 |
| 51 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.24246096 |
| 52 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.23252501 |
| 53 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.23012521 |
| 54 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.20826530 |
| 55 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.19762552 |
| 56 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.19742078 |
| 57 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.19022046 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.16597787 |
| 59 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16164575 |
| 60 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.15814561 |
| 61 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.15789686 |
| 62 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.14311399 |
| 63 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.13056070 |
| 64 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.11370491 |
| 65 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.10214058 |
| 66 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.09128811 |
| 67 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.08916592 |
| 68 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.08689316 |
| 69 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.08346805 |
| 70 | ERA_21632823_ChIP-Seq_H3396_Human | 1.08340012 |
| 71 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.05725291 |
| 72 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.04727846 |
| 73 | SA1_27219007_Chip-Seq_Bcells_Human | 1.04296748 |
| 74 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.02413352 |
| 75 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.02399100 |
| 76 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.01926656 |
| 77 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.01402868 |
| 78 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.00486614 |
| 79 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99908667 |
| 80 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.99528208 |
| 81 | EWS_26573619_Chip-Seq_HEK293_Human | 0.99411573 |
| 82 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.99141238 |
| 83 | NCOR_22424771_ChIP-Seq_293T_Human | 0.98966531 |
| 84 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.98307524 |
| 85 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97920574 |
| 86 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 0.97668462 |
| 87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.96966921 |
| 88 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.96747897 |
| 89 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.96396460 |
| 90 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.96384984 |
| 91 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96177586 |
| 92 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.95940287 |
| 93 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.93324366 |
| 94 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.93238759 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92160335 |
| 96 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.91790049 |
| 97 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.90621783 |
| 98 | P68_20966046_ChIP-Seq_HELA_Human | 0.90551665 |
| 99 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.90218063 |
| 100 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.90026339 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.34605258 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.65227677 |
| 3 | MP0005623_abnormal_meninges_morphology | 4.25364396 |
| 4 | MP0003136_yellow_coat_color | 2.62559530 |
| 5 | MP0002938_white_spotting | 2.61020961 |
| 6 | MP0004142_abnormal_muscle_tone | 2.47212986 |
| 7 | MP0002163_abnormal_gland_morphology | 2.32149557 |
| 8 | MP0000750_abnormal_muscle_regeneration | 2.29969640 |
| 9 | MP0003787_abnormal_imprinting | 2.21106315 |
| 10 | MP0005646_abnormal_pituitary_gland | 2.15865432 |
| 11 | MP0002638_abnormal_pupillary_reflex | 2.14371554 |
| 12 | MP0003123_paternal_imprinting | 2.03273002 |
| 13 | MP0003122_maternal_imprinting | 1.96545588 |
| 14 | MP0000566_synostosis | 1.92806710 |
| 15 | MP0000049_abnormal_middle_ear | 1.92642416 |
| 16 | MP0002837_dystrophic_cardiac_calcinosis | 1.83463090 |
| 17 | MP0003121_genomic_imprinting | 1.82661334 |
| 18 | MP0009384_cardiac_valve_regurgitation | 1.73480783 |
| 19 | MP0001485_abnormal_pinna_reflex | 1.69513410 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 1.67756335 |
| 21 | MP0003786_premature_aging | 1.65662649 |
| 22 | MP0006276_abnormal_autonomic_nervous | 1.65127336 |
| 23 | MP0003646_muscle_fatigue | 1.58187976 |
| 24 | MP0002653_abnormal_ependyma_morphology | 1.56876358 |
| 25 | MP0001293_anophthalmia | 1.53691036 |
| 26 | MP0008877_abnormal_DNA_methylation | 1.53425279 |
| 27 | MP0004145_abnormal_muscle_electrophysio | 1.44748162 |
| 28 | MP0005379_endocrine/exocrine_gland_phen | 1.44707871 |
| 29 | MP0000631_abnormal_neuroendocrine_gland | 1.40138074 |
| 30 | MP0002277_abnormal_respiratory_mucosa | 1.40040558 |
| 31 | MP0005551_abnormal_eye_electrophysiolog | 1.38338531 |
| 32 | MP0009046_muscle_twitch | 1.33827919 |
| 33 | MP0005499_abnormal_olfactory_system | 1.30841008 |
| 34 | MP0005394_taste/olfaction_phenotype | 1.30841008 |
| 35 | MP0002234_abnormal_pharynx_morphology | 1.29346943 |
| 36 | MP0004147_increased_porphyrin_level | 1.29261235 |
| 37 | MP0001968_abnormal_touch/_nociception | 1.28360390 |
| 38 | MP0004885_abnormal_endolymph | 1.28143124 |
| 39 | MP0010030_abnormal_orbit_morphology | 1.26997418 |
| 40 | MP0000762_abnormal_tongue_morphology | 1.25319888 |
| 41 | MP0000778_abnormal_nervous_system | 1.23539589 |
| 42 | MP0002272_abnormal_nervous_system | 1.19201639 |
| 43 | MP0001986_abnormal_taste_sensitivity | 1.17611960 |
| 44 | MP0002067_abnormal_sensory_capabilities | 1.16979765 |
| 45 | MP0002736_abnormal_nociception_after | 1.16403338 |
| 46 | MP0005195_abnormal_posterior_eye | 1.15449624 |
| 47 | MP0003938_abnormal_ear_development | 1.15091528 |
| 48 | MP0003385_abnormal_body_wall | 1.14617747 |
| 49 | MP0002876_abnormal_thyroid_physiology | 1.11098398 |
| 50 | MP0004742_abnormal_vestibular_system | 1.10805718 |
| 51 | MP0008058_abnormal_DNA_repair | 1.10554688 |
| 52 | MP0002184_abnormal_innervation | 1.10139287 |
| 53 | MP0005389_reproductive_system_phenotype | 1.08143568 |
| 54 | MP0002160_abnormal_reproductive_system | 1.06489127 |
| 55 | MP0003315_abnormal_perineum_morphology | 1.06144179 |
| 56 | MP0008872_abnormal_physiological_respon | 1.04382372 |
| 57 | MP0009745_abnormal_behavioral_response | 1.01131294 |
| 58 | MP0008775_abnormal_heart_ventricle | 1.00588646 |
| 59 | MP0001970_abnormal_pain_threshold | 0.99611690 |
| 60 | MP0000026_abnormal_inner_ear | 0.99066090 |
| 61 | MP0002752_abnormal_somatic_nervous | 0.98323582 |
| 62 | MP0002733_abnormal_thermal_nociception | 0.98052062 |
| 63 | MP0005084_abnormal_gallbladder_morpholo | 0.98040901 |
| 64 | MP0003186_abnormal_redox_activity | 0.96294513 |
| 65 | MP0002572_abnormal_emotion/affect_behav | 0.96129349 |
| 66 | MP0003879_abnormal_hair_cell | 0.94579160 |
| 67 | MP0003878_abnormal_ear_physiology | 0.93816302 |
| 68 | MP0005377_hearing/vestibular/ear_phenot | 0.93816302 |
| 69 | MP0003755_abnormal_palate_morphology | 0.93701195 |
| 70 | MP0000955_abnormal_spinal_cord | 0.93374833 |
| 71 | MP0001905_abnormal_dopamine_level | 0.92030529 |
| 72 | MP0003567_abnormal_fetal_cardiomyocyte | 0.91598923 |
| 73 | MP0002177_abnormal_outer_ear | 0.91308347 |
| 74 | MP0002063_abnormal_learning/memory/cond | 0.90049431 |
| 75 | MP0000613_abnormal_salivary_gland | 0.89568561 |
| 76 | MP0002735_abnormal_chemical_nociception | 0.89142500 |
| 77 | MP0008875_abnormal_xenobiotic_pharmacok | 0.88861885 |
| 78 | MP0003635_abnormal_synaptic_transmissio | 0.88390822 |
| 79 | MP0001919_abnormal_reproductive_system | 0.87566952 |
| 80 | MP0003693_abnormal_embryo_hatching | 0.87504149 |
| 81 | MP0002210_abnormal_sex_determination | 0.87471709 |
| 82 | MP0002095_abnormal_skin_pigmentation | 0.87132255 |
| 83 | MP0002249_abnormal_larynx_morphology | 0.84869131 |
| 84 | MP0005645_abnormal_hypothalamus_physiol | 0.84656651 |
| 85 | MP0009053_abnormal_anal_canal | 0.84199295 |
| 86 | MP0009250_abnormal_appendicular_skeleto | 0.83632812 |
| 87 | MP0003890_abnormal_embryonic-extraembry | 0.83207526 |
| 88 | MP0001529_abnormal_vocalization | 0.82003251 |
| 89 | MP0000013_abnormal_adipose_tissue | 0.80666912 |
| 90 | MP0002102_abnormal_ear_morphology | 0.78700286 |
| 91 | MP0005083_abnormal_biliary_tract | 0.74842341 |
| 92 | MP0005423_abnormal_somatic_nervous | 0.74711319 |
| 93 | MP0002557_abnormal_social/conspecific_i | 0.72446658 |
| 94 | MP0002064_seizures | 0.71432452 |
| 95 | MP0002882_abnormal_neuron_morphology | 0.70810517 |
| 96 | MP0003137_abnormal_impulse_conducting | 0.70682592 |
| 97 | MP0002152_abnormal_brain_morphology | 0.70109951 |
| 98 | MP0001188_hyperpigmentation | 0.68911827 |
| 99 | MP0004133_heterotaxia | 0.68729784 |
| 100 | MP0002138_abnormal_hepatobiliary_system | 0.68555791 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type II lissencephaly (HP:0007260) | 7.47251936 |
| 2 | Cerebellar dysplasia (HP:0007033) | 7.26318183 |
| 3 | Retinal atrophy (HP:0001105) | 6.10169607 |
| 4 | Hypoplasia of the pons (HP:0012110) | 5.83120982 |
| 5 | Retinal dysplasia (HP:0007973) | 5.82516643 |
| 6 | Abnormality of the pons (HP:0007361) | 5.30356249 |
| 7 | Reticulocytopenia (HP:0001896) | 4.52378070 |
| 8 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 4.49885749 |
| 9 | Acute necrotizing encephalopathy (HP:0006965) | 4.14190804 |
| 10 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.86281229 |
| 11 | Buphthalmos (HP:0000557) | 3.82323183 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.76013916 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.65738538 |
| 14 | Molar tooth sign on MRI (HP:0002419) | 3.65738538 |
| 15 | Abolished electroretinogram (ERG) (HP:0000550) | 3.61088789 |
| 16 | Pallor (HP:0000980) | 3.60563794 |
| 17 | Acute encephalopathy (HP:0006846) | 3.50307335 |
| 18 | Macrocytic anemia (HP:0001972) | 3.38745104 |
| 19 | Progressive macrocephaly (HP:0004481) | 3.33231837 |
| 20 | Fatigue (HP:0012378) | 3.32575677 |
| 21 | Mitochondrial inheritance (HP:0001427) | 3.31165028 |
| 22 | Abnormality of DNA repair (HP:0003254) | 3.21053978 |
| 23 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 3.17906036 |
| 24 | Lissencephaly (HP:0001339) | 3.12004215 |
| 25 | Severe muscular hypotonia (HP:0006829) | 3.08586467 |
| 26 | Abnormal number of erythroid precursors (HP:0012131) | 3.04908053 |
| 27 | Increased CSF lactate (HP:0002490) | 2.96032732 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.84005691 |
| 29 | Pachygyria (HP:0001302) | 2.74196576 |
| 30 | Pancreatic cysts (HP:0001737) | 2.58718674 |
| 31 | 3-Methylglutaconic aciduria (HP:0003535) | 2.56489641 |
| 32 | Cerebral edema (HP:0002181) | 2.54880369 |
| 33 | Nephronophthisis (HP:0000090) | 2.49410776 |
| 34 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.48032993 |
| 35 | Meningocele (HP:0002435) | 2.45823687 |
| 36 | True hermaphroditism (HP:0010459) | 2.41166519 |
| 37 | Entropion (HP:0000621) | 2.36134897 |
| 38 | Stenosis of the external auditory canal (HP:0000402) | 2.36065543 |
| 39 | Congenital glaucoma (HP:0001087) | 2.35913302 |
| 40 | Difficulty climbing stairs (HP:0003551) | 2.35702710 |
| 41 | Lipid accumulation in hepatocytes (HP:0006561) | 2.30346037 |
| 42 | Hepatocellular necrosis (HP:0001404) | 2.27909572 |
| 43 | Septo-optic dysplasia (HP:0100842) | 2.27671634 |
| 44 | Increased hepatocellular lipid droplets (HP:0006565) | 2.27383288 |
| 45 | Absent thumb (HP:0009777) | 2.26094283 |
| 46 | Hypoplasia of the brainstem (HP:0002365) | 2.24125376 |
| 47 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.24125376 |
| 48 | Absent/shortened dynein arms (HP:0200106) | 2.22250792 |
| 49 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.22250792 |
| 50 | Megalocornea (HP:0000485) | 2.20833293 |
| 51 | Holoprosencephaly (HP:0001360) | 2.18820789 |
| 52 | Renal Fanconi syndrome (HP:0001994) | 2.15354603 |
| 53 | Colon cancer (HP:0003003) | 2.14573936 |
| 54 | Generalized hypotonia (HP:0001290) | 2.13924203 |
| 55 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.12565098 |
| 56 | Chronic hepatic failure (HP:0100626) | 2.09172460 |
| 57 | Medial flaring of the eyebrow (HP:0010747) | 2.06664052 |
| 58 | Sclerocornea (HP:0000647) | 2.06166859 |
| 59 | Abnormality of the labia minora (HP:0012880) | 2.05096781 |
| 60 | Non-midline cleft lip (HP:0100335) | 2.04445421 |
| 61 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.04403886 |
| 62 | Hypoplasia of the radius (HP:0002984) | 2.04213083 |
| 63 | Hepatic necrosis (HP:0002605) | 2.03766238 |
| 64 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.03357398 |
| 65 | Asplenia (HP:0001746) | 2.00779557 |
| 66 | Poikiloderma (HP:0001029) | 1.96516219 |
| 67 | Intellectual disability, profound (HP:0002187) | 1.95714226 |
| 68 | Abnormality of the renal medulla (HP:0100957) | 1.95463664 |
| 69 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.94883950 |
| 70 | Partial duplication of thumb phalanx (HP:0009944) | 1.93313598 |
| 71 | Increased intramyocellular lipid droplets (HP:0012240) | 1.90893873 |
| 72 | Pendular nystagmus (HP:0012043) | 1.88760943 |
| 73 | Polydipsia (HP:0001959) | 1.88741049 |
| 74 | Abnormal drinking behavior (HP:0030082) | 1.88741049 |
| 75 | Respiratory failure (HP:0002878) | 1.88318503 |
| 76 | Decreased subcutaneous fat (HP:0001002) | 1.88121064 |
| 77 | Hyperglycinemia (HP:0002154) | 1.87040084 |
| 78 | Esophageal atresia (HP:0002032) | 1.85279088 |
| 79 | Optic disc pallor (HP:0000543) | 1.84834534 |
| 80 | Severe global developmental delay (HP:0011344) | 1.82028820 |
| 81 | Cystic liver disease (HP:0006706) | 1.80812914 |
| 82 | Abnormality of the vitreous humor (HP:0004327) | 1.78892793 |
| 83 | Fragile nails (HP:0001808) | 1.77222734 |
| 84 | Myokymia (HP:0002411) | 1.74611204 |
| 85 | Increased serum lactate (HP:0002151) | 1.74326524 |
| 86 | Dandy-Walker malformation (HP:0001305) | 1.74276871 |
| 87 | Anencephaly (HP:0002323) | 1.73673616 |
| 88 | Optic nerve coloboma (HP:0000588) | 1.73314823 |
| 89 | Lactic acidosis (HP:0003128) | 1.72380176 |
| 90 | Maternal diabetes (HP:0009800) | 1.71564353 |
| 91 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.68997426 |
| 92 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.68997426 |
| 93 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.68246629 |
| 94 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.67582195 |
| 95 | Rib fusion (HP:0000902) | 1.67399489 |
| 96 | Tubular atrophy (HP:0000092) | 1.67320238 |
| 97 | Generalized muscle weakness (HP:0003324) | 1.66361091 |
| 98 | Increased muscle lipid content (HP:0009058) | 1.66353323 |
| 99 | Depressed nasal ridge (HP:0000457) | 1.65128578 |
| 100 | IgG deficiency (HP:0004315) | 1.65034238 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MARK3 | 5.21938355 |
| 2 | STK10 | 4.31834935 |
| 3 | STK16 | 3.27943418 |
| 4 | WNK4 | 3.15639721 |
| 5 | DYRK2 | 2.43995966 |
| 6 | NME2 | 2.40386857 |
| 7 | BCKDK | 2.32057234 |
| 8 | STK11 | 2.32043898 |
| 9 | PIM1 | 2.21674663 |
| 10 | TLK1 | 2.14515958 |
| 11 | NUAK1 | 1.96709453 |
| 12 | CDK19 | 1.94289588 |
| 13 | TXK | 1.87951065 |
| 14 | PINK1 | 1.87440894 |
| 15 | WNK3 | 1.85225113 |
| 16 | ADRBK2 | 1.83613513 |
| 17 | GRK1 | 1.72874547 |
| 18 | TIE1 | 1.66656908 |
| 19 | CDC7 | 1.66441889 |
| 20 | VRK2 | 1.65399631 |
| 21 | PDK2 | 1.45601883 |
| 22 | STK39 | 1.43172364 |
| 23 | FRK | 1.40125456 |
| 24 | LRRK2 | 1.39341093 |
| 25 | NME1 | 1.36198349 |
| 26 | EPHB2 | 1.34917134 |
| 27 | CAMKK2 | 1.34316526 |
| 28 | CASK | 1.34126154 |
| 29 | PRKCH | 1.32399873 |
| 30 | WNK1 | 1.30983636 |
| 31 | PTK2B | 1.26805147 |
| 32 | NTRK2 | 1.26769187 |
| 33 | PLK4 | 1.23315592 |
| 34 | BMPR1B | 1.21775467 |
| 35 | OXSR1 | 1.16340756 |
| 36 | MAP3K11 | 1.14711658 |
| 37 | PRKCG | 1.13766706 |
| 38 | TNIK | 1.13210115 |
| 39 | TYRO3 | 1.09801199 |
| 40 | BUB1 | 0.99704146 |
| 41 | ABL2 | 0.98844275 |
| 42 | MAP2K2 | 0.97641769 |
| 43 | PRKD3 | 0.94213030 |
| 44 | MAP4K2 | 0.92705997 |
| 45 | SIK2 | 0.91605647 |
| 46 | ZAK | 0.85281788 |
| 47 | PIK3CA | 0.83470177 |
| 48 | NEK2 | 0.79666924 |
| 49 | AURKA | 0.79617748 |
| 50 | VRK1 | 0.74895326 |
| 51 | PRKCI | 0.72861287 |
| 52 | NEK1 | 0.72006934 |
| 53 | CAMK1 | 0.71347692 |
| 54 | CSNK2A2 | 0.71122690 |
| 55 | FGFR2 | 0.66901831 |
| 56 | RPS6KA5 | 0.66145288 |
| 57 | PIM2 | 0.61786201 |
| 58 | PHKG1 | 0.61343040 |
| 59 | PHKG2 | 0.61343040 |
| 60 | ADRBK1 | 0.61285764 |
| 61 | IKBKB | 0.61195906 |
| 62 | CSNK1E | 0.60124396 |
| 63 | DAPK3 | 0.58601003 |
| 64 | TAF1 | 0.57403899 |
| 65 | EIF2AK1 | 0.56752798 |
| 66 | PLK1 | 0.55734400 |
| 67 | NLK | 0.54970264 |
| 68 | MAP4K1 | 0.54906528 |
| 69 | TAOK3 | 0.54780132 |
| 70 | TEC | 0.54185915 |
| 71 | MINK1 | 0.54083173 |
| 72 | CAMK1D | 0.53959737 |
| 73 | MARK1 | 0.53406886 |
| 74 | PRKACA | 0.52623892 |
| 75 | RPS6KA6 | 0.52151833 |
| 76 | CSNK2A1 | 0.51366584 |
| 77 | AURKB | 0.49638179 |
| 78 | CSNK1G3 | 0.48576237 |
| 79 | INSRR | 0.47828201 |
| 80 | CSNK1G2 | 0.47261579 |
| 81 | PTK6 | 0.43913735 |
| 82 | CHEK2 | 0.43194429 |
| 83 | CAMKK1 | 0.42931238 |
| 84 | PRKCQ | 0.41891126 |
| 85 | MAP2K7 | 0.41860832 |
| 86 | PASK | 0.40453775 |
| 87 | DYRK1B | 0.37895947 |
| 88 | PAK3 | 0.37563284 |
| 89 | PRKCE | 0.37391501 |
| 90 | NTRK3 | 0.37233083 |
| 91 | OBSCN | 0.37161775 |
| 92 | TGFBR1 | 0.35408517 |
| 93 | CSNK1A1 | 0.34933750 |
| 94 | ITK | 0.34374089 |
| 95 | PRKCZ | 0.33965067 |
| 96 | ATR | 0.33921764 |
| 97 | CDK8 | 0.33540595 |
| 98 | PKN1 | 0.32861193 |
| 99 | STK4 | 0.32376500 |
| 100 | PRKCD | 0.32042877 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.48950754 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.64876612 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.98770268 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 2.99906349 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.84879797 |
| 6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.77065846 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.75191271 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.55712370 |
| 9 | Sulfur relay system_Homo sapiens_hsa04122 | 2.27586491 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.02969796 |
| 11 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.92102479 |
| 12 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.85831897 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.67634512 |
| 14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.61262252 |
| 15 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.57361682 |
| 16 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.56244960 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.56133177 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.49393360 |
| 19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.49046446 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.43421640 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.41870936 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.40161626 |
| 23 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.39651180 |
| 24 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.38992565 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.37634260 |
| 26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.37238710 |
| 27 | Protein export_Homo sapiens_hsa03060 | 1.24816652 |
| 28 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.16875355 |
| 29 | Mismatch repair_Homo sapiens_hsa03430 | 1.15664552 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.13117981 |
| 31 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.04016327 |
| 32 | Spliceosome_Homo sapiens_hsa03040 | 1.00036561 |
| 33 | Peroxisome_Homo sapiens_hsa04146 | 0.99462732 |
| 34 | Purine metabolism_Homo sapiens_hsa00230 | 0.96484581 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.92987284 |
| 36 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.91591874 |
| 37 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.87172731 |
| 38 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.83346848 |
| 39 | Nicotine addiction_Homo sapiens_hsa05033 | 0.83026632 |
| 40 | Asthma_Homo sapiens_hsa05310 | 0.82477377 |
| 41 | Base excision repair_Homo sapiens_hsa03410 | 0.81913974 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.80287735 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 0.79910617 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.79469101 |
| 45 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76462519 |
| 46 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.72782666 |
| 47 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.70599994 |
| 48 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.66328025 |
| 49 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.64265220 |
| 50 | Phototransduction_Homo sapiens_hsa04744 | 0.63394016 |
| 51 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.62492198 |
| 52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.60560683 |
| 53 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59931517 |
| 54 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58634495 |
| 55 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.57237612 |
| 56 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.55947648 |
| 57 | Retinol metabolism_Homo sapiens_hsa00830 | 0.55465289 |
| 58 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.54852893 |
| 59 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53954726 |
| 60 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.51842353 |
| 61 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.50748767 |
| 62 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.49320127 |
| 63 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.48771997 |
| 64 | Insulin secretion_Homo sapiens_hsa04911 | 0.48228901 |
| 65 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.48115714 |
| 66 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.47727054 |
| 67 | Olfactory transduction_Homo sapiens_hsa04740 | 0.45882174 |
| 68 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.43761463 |
| 69 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.43002147 |
| 70 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.42731384 |
| 71 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.41260849 |
| 72 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.38181015 |
| 73 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.37745938 |
| 74 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.37460791 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.36369504 |
| 76 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36282075 |
| 77 | Allograft rejection_Homo sapiens_hsa05330 | 0.35421824 |
| 78 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.34050653 |
| 79 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.33964585 |
| 80 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33751856 |
| 81 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.31620869 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.31256302 |
| 83 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.31113459 |
| 84 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.30650694 |
| 85 | Taste transduction_Homo sapiens_hsa04742 | 0.27085584 |
| 86 | Morphine addiction_Homo sapiens_hsa05032 | 0.26424892 |
| 87 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.26249435 |
| 88 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.26202549 |
| 89 | Mineral absorption_Homo sapiens_hsa04978 | 0.25833560 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.25302191 |
| 91 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.24057621 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.22644848 |
| 93 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.21436815 |
| 94 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.21334304 |
| 95 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.19771751 |
| 96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.19656098 |
| 97 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.19322338 |
| 98 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.17154886 |
| 99 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.16674762 |
| 100 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.14191939 |

