

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.21791556 |
| 2 | maturation of SSU-rRNA (GO:0030490) | 7.14644434 |
| 3 | viral transcription (GO:0019083) | 6.95162042 |
| 4 | translational termination (GO:0006415) | 6.68393989 |
| 5 | ribosomal small subunit biogenesis (GO:0042274) | 6.40967506 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.80346608 |
| 7 | translational elongation (GO:0006414) | 5.80129976 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 5.74108366 |
| 9 | protein targeting to ER (GO:0045047) | 5.68982545 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.45913698 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 5.38923255 |
| 12 | chaperone-mediated protein transport (GO:0072321) | 5.38676962 |
| 13 | viral life cycle (GO:0019058) | 5.20661896 |
| 14 | cellular protein complex disassembly (GO:0043624) | 5.15386397 |
| 15 | behavioral response to nicotine (GO:0035095) | 4.92439790 |
| 16 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.87781149 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.66000641 |
| 18 | ATP synthesis coupled proton transport (GO:0015986) | 4.66000641 |
| 19 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.62611080 |
| 20 | translational initiation (GO:0006413) | 4.51013412 |
| 21 | protein complex disassembly (GO:0043241) | 4.41719051 |
| 22 | ribosomal large subunit biogenesis (GO:0042273) | 4.34370520 |
| 23 | protein complex biogenesis (GO:0070271) | 4.27342611 |
| 24 | macromolecular complex disassembly (GO:0032984) | 4.19506651 |
| 25 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.18306819 |
| 26 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.18306819 |
| 27 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.15422762 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.15422762 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 4.15422762 |
| 30 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.15361309 |
| 31 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.11541863 |
| 32 | translation (GO:0006412) | 4.05259823 |
| 33 | protein neddylation (GO:0045116) | 4.04037869 |
| 34 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.01331623 |
| 35 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.92818198 |
| 36 | regulation of cilium movement (GO:0003352) | 3.91022644 |
| 37 | GTP biosynthetic process (GO:0006183) | 3.89918182 |
| 38 | protein targeting to membrane (GO:0006612) | 3.88717873 |
| 39 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.86068967 |
| 40 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.80132003 |
| 41 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.80132003 |
| 42 | respiratory electron transport chain (GO:0022904) | 3.64962308 |
| 43 | electron transport chain (GO:0022900) | 3.64002433 |
| 44 | cellular component biogenesis (GO:0044085) | 3.57610180 |
| 45 | termination of RNA polymerase III transcription (GO:0006386) | 3.53943840 |
| 46 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.53943840 |
| 47 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.52640078 |
| 48 | pattern specification involved in kidney development (GO:0061004) | 3.44978471 |
| 49 | UTP biosynthetic process (GO:0006228) | 3.36498466 |
| 50 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.35050160 |
| 51 | nonmotile primary cilium assembly (GO:0035058) | 3.33472777 |
| 52 | mRNA catabolic process (GO:0006402) | 3.33456931 |
| 53 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.33450570 |
| 54 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.26476598 |
| 55 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.19430815 |
| 56 | DNA deamination (GO:0045006) | 3.18268108 |
| 57 | base-excision repair, AP site formation (GO:0006285) | 3.16080206 |
| 58 | CTP metabolic process (GO:0046036) | 3.15847142 |
| 59 | CTP biosynthetic process (GO:0006241) | 3.15847142 |
| 60 | ubiquinone biosynthetic process (GO:0006744) | 3.14937436 |
| 61 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.14586909 |
| 62 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.14009803 |
| 63 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.12545832 |
| 64 | UTP metabolic process (GO:0046051) | 3.10292834 |
| 65 | cell proliferation in forebrain (GO:0021846) | 3.06533109 |
| 66 | RNA catabolic process (GO:0006401) | 3.02526234 |
| 67 | positive regulation of T cell apoptotic process (GO:0070234) | 3.00456564 |
| 68 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.99810020 |
| 69 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.97382528 |
| 70 | rRNA processing (GO:0006364) | 2.86865275 |
| 71 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.84532074 |
| 72 | rRNA metabolic process (GO:0016072) | 2.81732173 |
| 73 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.81381294 |
| 74 | segment specification (GO:0007379) | 2.79828262 |
| 75 | ubiquinone metabolic process (GO:0006743) | 2.78986406 |
| 76 | regulation of microtubule-based movement (GO:0060632) | 2.77719503 |
| 77 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.74577610 |
| 78 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.73470059 |
| 79 | protein deneddylation (GO:0000338) | 2.73357688 |
| 80 | cullin deneddylation (GO:0010388) | 2.72911150 |
| 81 | protein targeting to mitochondrion (GO:0006626) | 2.71717536 |
| 82 | ATP biosynthetic process (GO:0006754) | 2.71354812 |
| 83 | protein targeting (GO:0006605) | 2.71224910 |
| 84 | negative regulation of telomere maintenance (GO:0032205) | 2.68707342 |
| 85 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.64972785 |
| 86 | establishment of protein localization to membrane (GO:0090150) | 2.63772455 |
| 87 | tRNA processing (GO:0008033) | 2.62742314 |
| 88 | deoxyribonucleotide catabolic process (GO:0009264) | 2.61558077 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.60884535 |
| 90 | hydrogen ion transmembrane transport (GO:1902600) | 2.60861687 |
| 91 | establishment of protein localization to mitochondrion (GO:0072655) | 2.60032427 |
| 92 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.59158421 |
| 93 | sequestering of actin monomers (GO:0042989) | 2.56213956 |
| 94 | ncRNA 3-end processing (GO:0043628) | 2.56163792 |
| 95 | positive regulation of protein homooligomerization (GO:0032464) | 2.54209307 |
| 96 | quinone biosynthetic process (GO:1901663) | 2.54013661 |
| 97 | chromatin remodeling at centromere (GO:0031055) | 2.49461903 |
| 98 | epithelial cilium movement (GO:0003351) | 2.49373561 |
| 99 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.48091591 |
| 100 | respiratory chain complex IV assembly (GO:0008535) | 2.48002176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.24258479 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.98078547 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.87106947 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.55084644 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.30008242 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.21037888 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.18665473 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.04413029 |
| 9 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.71973876 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.66476206 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.63280738 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.55021213 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.45455484 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.32894484 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.28692529 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.24385674 |
| 17 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.17864258 |
| 18 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.13420876 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.07314182 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.04528128 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.04417510 |
| 22 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.99950569 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.99332927 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.97276246 |
| 25 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89431798 |
| 26 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.87956068 |
| 27 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.83382130 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.83148390 |
| 29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.81451143 |
| 30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.77930350 |
| 31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.76808605 |
| 32 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.76576016 |
| 33 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.75408404 |
| 34 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.73105616 |
| 35 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.64742869 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.64504557 |
| 37 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.59772814 |
| 38 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.56849323 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.48320110 |
| 40 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.43989094 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.43683811 |
| 42 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.42920449 |
| 43 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.42012198 |
| 44 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.39872980 |
| 45 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.37442951 |
| 46 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.32813016 |
| 47 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.32399160 |
| 48 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.30351117 |
| 49 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.29064012 |
| 50 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.28353770 |
| 51 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24999423 |
| 52 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.24702661 |
| 53 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.23494169 |
| 54 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.20261884 |
| 55 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.20206408 |
| 56 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.19900450 |
| 57 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.13364528 |
| 58 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.12550681 |
| 59 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.12109001 |
| 60 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.10836494 |
| 61 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.10721997 |
| 62 | NCOR_22424771_ChIP-Seq_293T_Human | 1.09783110 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09314793 |
| 64 | ERA_21632823_ChIP-Seq_H3396_Human | 1.08839001 |
| 65 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08703268 |
| 66 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.08649017 |
| 67 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.08283514 |
| 68 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.06272737 |
| 69 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.05866873 |
| 70 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05604050 |
| 71 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04768416 |
| 72 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.04077690 |
| 73 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.02602723 |
| 74 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.01583853 |
| 75 | EWS_26573619_Chip-Seq_HEK293_Human | 0.98912986 |
| 76 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.97951624 |
| 77 | FUS_26573619_Chip-Seq_HEK293_Human | 0.97565668 |
| 78 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 0.97535539 |
| 79 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.97184577 |
| 80 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.95959234 |
| 81 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.94879586 |
| 82 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.94373586 |
| 83 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.94046912 |
| 84 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.92656117 |
| 85 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.92308314 |
| 86 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.91101017 |
| 87 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.89794150 |
| 88 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.88269724 |
| 89 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.88240356 |
| 90 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.87882191 |
| 91 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.86639655 |
| 92 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.86623548 |
| 93 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.86596275 |
| 94 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.86092063 |
| 95 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.84318071 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.84184613 |
| 97 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.84143977 |
| 98 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.83623074 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.80556247 |
| 100 | AR_20517297_ChIP-Seq_VCAP_Human | 0.80294994 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.65590659 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.21070970 |
| 3 | MP0003123_paternal_imprinting | 3.80454021 |
| 4 | MP0003787_abnormal_imprinting | 3.64769675 |
| 5 | MP0002653_abnormal_ependyma_morphology | 2.85223952 |
| 6 | MP0008789_abnormal_olfactory_epithelium | 2.83403855 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.10063801 |
| 8 | MP0005646_abnormal_pituitary_gland | 2.06699441 |
| 9 | MP0003121_genomic_imprinting | 2.04837308 |
| 10 | MP0004142_abnormal_muscle_tone | 1.98923260 |
| 11 | MP0006276_abnormal_autonomic_nervous | 1.98330350 |
| 12 | MP0005394_taste/olfaction_phenotype | 1.96361807 |
| 13 | MP0005499_abnormal_olfactory_system | 1.96361807 |
| 14 | MP0001968_abnormal_touch/_nociception | 1.92788485 |
| 15 | MP0005377_hearing/vestibular/ear_phenot | 1.90480173 |
| 16 | MP0003878_abnormal_ear_physiology | 1.90480173 |
| 17 | MP0002138_abnormal_hepatobiliary_system | 1.83753756 |
| 18 | MP0001293_anophthalmia | 1.82723270 |
| 19 | MP0001529_abnormal_vocalization | 1.75024620 |
| 20 | MP0003122_maternal_imprinting | 1.74483792 |
| 21 | MP0002163_abnormal_gland_morphology | 1.72491793 |
| 22 | MP0002736_abnormal_nociception_after | 1.64414378 |
| 23 | MP0002160_abnormal_reproductive_system | 1.63788685 |
| 24 | MP0002272_abnormal_nervous_system | 1.62397155 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.62331163 |
| 26 | MP0000049_abnormal_middle_ear | 1.62008387 |
| 27 | MP0004885_abnormal_endolymph | 1.61754962 |
| 28 | MP0001986_abnormal_taste_sensitivity | 1.59097743 |
| 29 | MP0001984_abnormal_olfaction | 1.57238668 |
| 30 | MP0001485_abnormal_pinna_reflex | 1.50784329 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.49852357 |
| 32 | MP0003646_muscle_fatigue | 1.44181288 |
| 33 | MP0005389_reproductive_system_phenotype | 1.43922228 |
| 34 | MP0003880_abnormal_central_pattern | 1.41132967 |
| 35 | MP0008872_abnormal_physiological_respon | 1.40283188 |
| 36 | MP0000631_abnormal_neuroendocrine_gland | 1.40206471 |
| 37 | MP0010030_abnormal_orbit_morphology | 1.39345098 |
| 38 | MP0001905_abnormal_dopamine_level | 1.39059335 |
| 39 | MP0005551_abnormal_eye_electrophysiolog | 1.38754190 |
| 40 | MP0002938_white_spotting | 1.38559239 |
| 41 | MP0004133_heterotaxia | 1.31575790 |
| 42 | MP0002837_dystrophic_cardiac_calcinosis | 1.29279044 |
| 43 | MP0000778_abnormal_nervous_system | 1.28764616 |
| 44 | MP0002557_abnormal_social/conspecific_i | 1.28700606 |
| 45 | MP0004147_increased_porphyrin_level | 1.27595772 |
| 46 | MP0002876_abnormal_thyroid_physiology | 1.23016998 |
| 47 | MP0004145_abnormal_muscle_electrophysio | 1.22665330 |
| 48 | MP0003186_abnormal_redox_activity | 1.19647075 |
| 49 | MP0005084_abnormal_gallbladder_morpholo | 1.19411048 |
| 50 | MP0009745_abnormal_behavioral_response | 1.19345740 |
| 51 | MP0002102_abnormal_ear_morphology | 1.17931666 |
| 52 | MP0003136_yellow_coat_color | 1.16780577 |
| 53 | MP0001873_stomach_inflammation | 1.14914500 |
| 54 | MP0006072_abnormal_retinal_apoptosis | 1.13718143 |
| 55 | MP0005360_urolithiasis | 1.12081165 |
| 56 | MP0001440_abnormal_grooming_behavior | 1.11757378 |
| 57 | MP0000026_abnormal_inner_ear | 1.10769685 |
| 58 | MP0002733_abnormal_thermal_nociception | 1.08179451 |
| 59 | MP0002572_abnormal_emotion/affect_behav | 1.05410931 |
| 60 | MP0001970_abnormal_pain_threshold | 1.05406851 |
| 61 | MP0002184_abnormal_innervation | 1.04901593 |
| 62 | MP0000955_abnormal_spinal_cord | 1.04716701 |
| 63 | MP0005645_abnormal_hypothalamus_physiol | 1.03461386 |
| 64 | MP0008775_abnormal_heart_ventricle | 1.03396073 |
| 65 | MP0005423_abnormal_somatic_nervous | 1.02945327 |
| 66 | MP0002095_abnormal_skin_pigmentation | 1.01215637 |
| 67 | MP0003315_abnormal_perineum_morphology | 1.01048581 |
| 68 | MP0002233_abnormal_nose_morphology | 1.00757694 |
| 69 | MP0002210_abnormal_sex_determination | 0.99592652 |
| 70 | MP0005379_endocrine/exocrine_gland_phen | 0.97595051 |
| 71 | MP0001919_abnormal_reproductive_system | 0.97276434 |
| 72 | MP0009046_muscle_twitch | 0.96451724 |
| 73 | MP0003119_abnormal_digestive_system | 0.95829534 |
| 74 | MP0001486_abnormal_startle_reflex | 0.95662337 |
| 75 | MP0009053_abnormal_anal_canal | 0.93677479 |
| 76 | MP0002752_abnormal_somatic_nervous | 0.93393064 |
| 77 | MP0005195_abnormal_posterior_eye | 0.93192984 |
| 78 | MP0003718_maternal_effect | 0.92559334 |
| 79 | MP0008058_abnormal_DNA_repair | 0.89734817 |
| 80 | MP0003937_abnormal_limbs/digits/tail_de | 0.86845230 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.86401949 |
| 82 | MP0000613_abnormal_salivary_gland | 0.85767223 |
| 83 | MP0002063_abnormal_learning/memory/cond | 0.83497378 |
| 84 | MP0002638_abnormal_pupillary_reflex | 0.81302099 |
| 85 | MP0004742_abnormal_vestibular_system | 0.81268440 |
| 86 | MP0003635_abnormal_synaptic_transmissio | 0.80492252 |
| 87 | MP0003786_premature_aging | 0.80386758 |
| 88 | MP0009250_abnormal_appendicular_skeleto | 0.80274443 |
| 89 | MP0002234_abnormal_pharynx_morphology | 0.79626687 |
| 90 | MP0000427_abnormal_hair_cycle | 0.77915007 |
| 91 | MP0003942_abnormal_urinary_system | 0.77661229 |
| 92 | MP0005636_abnormal_mineral_homeostasis | 0.75305647 |
| 93 | MP0002735_abnormal_chemical_nociception | 0.75299085 |
| 94 | MP0002067_abnormal_sensory_capabilities | 0.73778390 |
| 95 | MP0000230_abnormal_systemic_arterial | 0.71944814 |
| 96 | MP0001145_abnormal_male_reproductive | 0.70460485 |
| 97 | MP0000653_abnormal_sex_gland | 0.69074828 |
| 98 | MP0002882_abnormal_neuron_morphology | 0.67897387 |
| 99 | MP0006036_abnormal_mitochondrial_physio | 0.67442424 |
| 100 | MP0003936_abnormal_reproductive_system | 0.67083141 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 4.93556055 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.46621558 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.28400472 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.97556917 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.93803449 |
| 6 | Pancreatic fibrosis (HP:0100732) | 3.85007943 |
| 7 | Type II lissencephaly (HP:0007260) | 3.78796320 |
| 8 | Acute encephalopathy (HP:0006846) | 3.77223758 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.61335148 |
| 10 | Increased CSF lactate (HP:0002490) | 3.61011242 |
| 11 | Macrocytic anemia (HP:0001972) | 3.52032128 |
| 12 | Abnormal number of erythroid precursors (HP:0012131) | 3.49190542 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.40652737 |
| 14 | Molar tooth sign on MRI (HP:0002419) | 3.40652737 |
| 15 | Pancreatic cysts (HP:0001737) | 3.29190990 |
| 16 | Hepatic necrosis (HP:0002605) | 3.29058499 |
| 17 | Hepatocellular necrosis (HP:0001404) | 3.28105970 |
| 18 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.27898353 |
| 19 | Increased hepatocellular lipid droplets (HP:0006565) | 3.10888876 |
| 20 | Adrenal hypoplasia (HP:0000835) | 3.03128220 |
| 21 | Colon cancer (HP:0003003) | 2.99243548 |
| 22 | Pendular nystagmus (HP:0012043) | 2.96663554 |
| 23 | True hermaphroditism (HP:0010459) | 2.90125340 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.87104588 |
| 25 | Medial flaring of the eyebrow (HP:0010747) | 2.83822983 |
| 26 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.80054003 |
| 27 | Cerebral edema (HP:0002181) | 2.75625253 |
| 28 | Myokymia (HP:0002411) | 2.75216444 |
| 29 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.70912748 |
| 30 | Rib fusion (HP:0000902) | 2.62945736 |
| 31 | Renal Fanconi syndrome (HP:0001994) | 2.55888728 |
| 32 | Stenosis of the external auditory canal (HP:0000402) | 2.55665041 |
| 33 | Absent thumb (HP:0009777) | 2.50378578 |
| 34 | Pallor (HP:0000980) | 2.47749904 |
| 35 | Sclerocornea (HP:0000647) | 2.47142457 |
| 36 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.46505602 |
| 37 | Asplenia (HP:0001746) | 2.45757657 |
| 38 | Optic disc pallor (HP:0000543) | 2.44852283 |
| 39 | Anencephaly (HP:0002323) | 2.44173730 |
| 40 | Gait imbalance (HP:0002141) | 2.44111890 |
| 41 | Increased serum lactate (HP:0002151) | 2.43932549 |
| 42 | Congenital primary aphakia (HP:0007707) | 2.43197396 |
| 43 | Congenital stationary night blindness (HP:0007642) | 2.38111906 |
| 44 | Hyperglycinemia (HP:0002154) | 2.34744936 |
| 45 | Cerebellar dysplasia (HP:0007033) | 2.31269559 |
| 46 | Nephrogenic diabetes insipidus (HP:0009806) | 2.30844250 |
| 47 | Abnormality of alanine metabolism (HP:0010916) | 2.30630754 |
| 48 | Hyperalaninemia (HP:0003348) | 2.30630754 |
| 49 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.30630754 |
| 50 | Nephronophthisis (HP:0000090) | 2.29114721 |
| 51 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.28117460 |
| 52 | Abnormality of DNA repair (HP:0003254) | 2.27375696 |
| 53 | Lactic acidosis (HP:0003128) | 2.24919174 |
| 54 | Retinal dysplasia (HP:0007973) | 2.24487072 |
| 55 | Septo-optic dysplasia (HP:0100842) | 2.23920390 |
| 56 | Lissencephaly (HP:0001339) | 2.18089812 |
| 57 | 3-Methylglutaconic aciduria (HP:0003535) | 2.17195689 |
| 58 | Abnormality of the labia minora (HP:0012880) | 2.16264988 |
| 59 | Increased intramyocellular lipid droplets (HP:0012240) | 2.11281891 |
| 60 | Cystic liver disease (HP:0006706) | 2.08497915 |
| 61 | Anophthalmia (HP:0000528) | 2.08446679 |
| 62 | Pachygyria (HP:0001302) | 2.08149392 |
| 63 | Postaxial foot polydactyly (HP:0001830) | 2.06797819 |
| 64 | Type 2 muscle fiber atrophy (HP:0003554) | 2.05133605 |
| 65 | Renal cortical cysts (HP:0000803) | 2.05041473 |
| 66 | Exertional dyspnea (HP:0002875) | 2.02486294 |
| 67 | Abnormality of urine glucose concentration (HP:0011016) | 1.99663214 |
| 68 | Glycosuria (HP:0003076) | 1.99663214 |
| 69 | Generalized aminoaciduria (HP:0002909) | 1.99494977 |
| 70 | Respiratory difficulties (HP:0002880) | 1.99431604 |
| 71 | Exercise intolerance (HP:0003546) | 1.98756421 |
| 72 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.96098884 |
| 73 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.96098884 |
| 74 | Depressed nasal ridge (HP:0000457) | 1.95116951 |
| 75 | Abolished electroretinogram (ERG) (HP:0000550) | 1.95081716 |
| 76 | Respiratory failure (HP:0002878) | 1.92554510 |
| 77 | Abnormality of the renal medulla (HP:0100957) | 1.92319633 |
| 78 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.89969768 |
| 79 | Preaxial hand polydactyly (HP:0001177) | 1.89548591 |
| 80 | Aplastic anemia (HP:0001915) | 1.88409910 |
| 81 | Abnormality of magnesium homeostasis (HP:0004921) | 1.88159040 |
| 82 | Anterior segment dysgenesis (HP:0007700) | 1.87731615 |
| 83 | Attenuation of retinal blood vessels (HP:0007843) | 1.84819019 |
| 84 | Leukodystrophy (HP:0002415) | 1.84816866 |
| 85 | Hyperphosphaturia (HP:0003109) | 1.83377258 |
| 86 | Muscle fiber atrophy (HP:0100295) | 1.81426550 |
| 87 | Median cleft lip (HP:0000161) | 1.80356212 |
| 88 | Severe muscular hypotonia (HP:0006829) | 1.79701333 |
| 89 | Forearm undergrowth (HP:0009821) | 1.78533416 |
| 90 | Lethargy (HP:0001254) | 1.77889364 |
| 91 | Hypoplasia of the radius (HP:0002984) | 1.77869740 |
| 92 | Hypoplasia of the ulna (HP:0003022) | 1.77689472 |
| 93 | Poor coordination (HP:0002370) | 1.74378924 |
| 94 | Holoprosencephaly (HP:0001360) | 1.73947771 |
| 95 | Abnormality of the renal cortex (HP:0011035) | 1.73686840 |
| 96 | Horseshoe kidney (HP:0000085) | 1.72846948 |
| 97 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.72095446 |
| 98 | Congenital hepatic fibrosis (HP:0002612) | 1.71467617 |
| 99 | Vaginal atresia (HP:0000148) | 1.71251587 |
| 100 | Methylmalonic acidemia (HP:0002912) | 1.69998397 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.85175915 |
| 2 | WNK4 | 3.16834361 |
| 3 | ZAK | 3.02600891 |
| 4 | ARAF | 2.80133346 |
| 5 | NME2 | 2.75049655 |
| 6 | CDK19 | 2.64851034 |
| 7 | STK16 | 2.63717983 |
| 8 | TLK1 | 2.51281769 |
| 9 | BCKDK | 2.34753998 |
| 10 | LIMK1 | 2.22436298 |
| 11 | DYRK2 | 2.21648350 |
| 12 | FRK | 2.18176009 |
| 13 | PIM2 | 2.14453229 |
| 14 | TIE1 | 1.95891433 |
| 15 | ADRBK2 | 1.94936750 |
| 16 | TAF1 | 1.79873509 |
| 17 | VRK1 | 1.77470250 |
| 18 | PDK2 | 1.70076544 |
| 19 | GRK1 | 1.65417895 |
| 20 | NUAK1 | 1.59501322 |
| 21 | MAP4K2 | 1.49782370 |
| 22 | TRIM28 | 1.49599987 |
| 23 | TXK | 1.42980119 |
| 24 | EPHB2 | 1.38745617 |
| 25 | PIK3CA | 1.38487318 |
| 26 | MAP2K7 | 1.38048007 |
| 27 | BRAF | 1.36719306 |
| 28 | CASK | 1.31852274 |
| 29 | PHKG1 | 1.31451349 |
| 30 | PHKG2 | 1.31451349 |
| 31 | TESK2 | 1.27081676 |
| 32 | STK39 | 1.26591715 |
| 33 | AURKA | 1.23209970 |
| 34 | LRRK2 | 1.22873477 |
| 35 | BMPR1B | 1.20346632 |
| 36 | MAP3K11 | 1.11639070 |
| 37 | TESK1 | 1.06087992 |
| 38 | INSRR | 1.00356000 |
| 39 | NME1 | 0.99345289 |
| 40 | TNIK | 0.98108768 |
| 41 | CDK8 | 0.97871442 |
| 42 | CSNK1G2 | 0.97383848 |
| 43 | CDC7 | 0.93836019 |
| 44 | PLK1 | 0.90915123 |
| 45 | CSNK1G3 | 0.89057427 |
| 46 | NEK1 | 0.87779902 |
| 47 | PRKCG | 0.87681569 |
| 48 | PLK3 | 0.86392311 |
| 49 | PINK1 | 0.85941611 |
| 50 | WNK1 | 0.85238184 |
| 51 | EPHA4 | 0.84711870 |
| 52 | CHEK2 | 0.82525448 |
| 53 | RPS6KA5 | 0.78109261 |
| 54 | DAPK3 | 0.77718506 |
| 55 | ADRBK1 | 0.77512177 |
| 56 | PRKCI | 0.77087870 |
| 57 | DAPK2 | 0.73433956 |
| 58 | TNK2 | 0.72279629 |
| 59 | CSNK1G1 | 0.70507431 |
| 60 | DAPK1 | 0.70099406 |
| 61 | NTRK2 | 0.67191861 |
| 62 | AURKB | 0.65744717 |
| 63 | CSNK1A1L | 0.63981921 |
| 64 | MINK1 | 0.61772410 |
| 65 | CAMK1 | 0.61638274 |
| 66 | GRK5 | 0.60769569 |
| 67 | WNK3 | 0.60529927 |
| 68 | MAP3K9 | 0.59962013 |
| 69 | ABL2 | 0.59597978 |
| 70 | CSNK2A2 | 0.59102305 |
| 71 | SRPK1 | 0.57827544 |
| 72 | PASK | 0.54817248 |
| 73 | PLK2 | 0.54124841 |
| 74 | STK11 | 0.50233359 |
| 75 | CSNK2A1 | 0.49634878 |
| 76 | OXSR1 | 0.47897506 |
| 77 | PRKACA | 0.47489844 |
| 78 | BUB1 | 0.46740572 |
| 79 | ATR | 0.46640838 |
| 80 | EPHA2 | 0.46291645 |
| 81 | RPS6KA6 | 0.46108386 |
| 82 | TGFBR1 | 0.46080453 |
| 83 | MST4 | 0.45871223 |
| 84 | PRKCQ | 0.45618522 |
| 85 | MAP2K6 | 0.45233769 |
| 86 | TAOK3 | 0.44518163 |
| 87 | MOS | 0.44010988 |
| 88 | TYRO3 | 0.43359361 |
| 89 | CAMKK2 | 0.42014358 |
| 90 | LMTK2 | 0.41841124 |
| 91 | DYRK3 | 0.41693576 |
| 92 | MAP3K4 | 0.39214614 |
| 93 | MAP3K12 | 0.38217477 |
| 94 | OBSCN | 0.36117188 |
| 95 | PIM1 | 0.35754901 |
| 96 | CAMK4 | 0.35335816 |
| 97 | PLK4 | 0.34178691 |
| 98 | DYRK1B | 0.33609152 |
| 99 | MUSK | 0.33146569 |
| 100 | RPS6KC1 | 0.31760410 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.34642645 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.05967311 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.43577890 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 3.19456188 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.09930734 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.57787099 |
| 7 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.37769558 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.30093897 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.26529484 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.01314511 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.00847375 |
| 12 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.93116617 |
| 13 | Mismatch repair_Homo sapiens_hsa03430 | 1.85531501 |
| 14 | Protein export_Homo sapiens_hsa03060 | 1.79621440 |
| 15 | Sulfur relay system_Homo sapiens_hsa04122 | 1.79493741 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.77668177 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.73043992 |
| 18 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.70667524 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.63198764 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.57295074 |
| 21 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.50084717 |
| 22 | Base excision repair_Homo sapiens_hsa03410 | 1.48623842 |
| 23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.43574216 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.42445034 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.40382009 |
| 26 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.27660942 |
| 27 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.26570534 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.24473698 |
| 29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.22697832 |
| 30 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.15683745 |
| 31 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.12691558 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.08079337 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.06234632 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 1.04236916 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.02958074 |
| 36 | Nicotine addiction_Homo sapiens_hsa05033 | 1.00661919 |
| 37 | Asthma_Homo sapiens_hsa05310 | 0.99872944 |
| 38 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.99260230 |
| 39 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.94352295 |
| 40 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.92100053 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.89637900 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.84425454 |
| 43 | RNA transport_Homo sapiens_hsa03013 | 0.83899814 |
| 44 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81868439 |
| 45 | Metabolic pathways_Homo sapiens_hsa01100 | 0.77976588 |
| 46 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77502456 |
| 47 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.76763362 |
| 48 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.75922683 |
| 49 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.74259713 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.73677667 |
| 51 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.73456925 |
| 52 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.72983689 |
| 53 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72731058 |
| 54 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.71181854 |
| 55 | Spliceosome_Homo sapiens_hsa03040 | 0.70557611 |
| 56 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.69440249 |
| 57 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.68944142 |
| 58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.66717776 |
| 59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63197974 |
| 60 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.60722707 |
| 61 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.58984256 |
| 62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.57029749 |
| 63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.56754312 |
| 64 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.56608743 |
| 65 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.56428623 |
| 66 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55035925 |
| 67 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.54509949 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.54450667 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53281416 |
| 70 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.53137307 |
| 71 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.52894954 |
| 72 | Salivary secretion_Homo sapiens_hsa04970 | 0.52672827 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.52169886 |
| 74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.50013482 |
| 75 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.49353526 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.49228097 |
| 77 | Allograft rejection_Homo sapiens_hsa05330 | 0.49083382 |
| 78 | Retinol metabolism_Homo sapiens_hsa00830 | 0.48505317 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.44568028 |
| 80 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44217291 |
| 81 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.43954222 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.40530611 |
| 83 | Morphine addiction_Homo sapiens_hsa05032 | 0.38858989 |
| 84 | Insulin secretion_Homo sapiens_hsa04911 | 0.37438244 |
| 85 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.36394454 |
| 86 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.36214469 |
| 87 | Carbon metabolism_Homo sapiens_hsa01200 | 0.33981434 |
| 88 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33787139 |
| 89 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.33687175 |
| 90 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33286000 |
| 91 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.32146607 |
| 92 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.31906949 |
| 93 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.28215145 |
| 94 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.26006544 |
| 95 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.23690447 |
| 96 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.20525689 |
| 97 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.20417233 |
| 98 | GABAergic synapse_Homo sapiens_hsa04727 | 0.19648977 |
| 99 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.18392606 |
| 100 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.16751884 |

