

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.99871281 |
| 2 | DNA deamination (GO:0045006) | 6.29338250 |
| 3 | cytidine metabolic process (GO:0046087) | 5.58942309 |
| 4 | cytidine catabolic process (GO:0006216) | 5.58942309 |
| 5 | cytidine deamination (GO:0009972) | 5.58942309 |
| 6 | viral transcription (GO:0019083) | 5.58167080 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.48364065 |
| 8 | translational termination (GO:0006415) | 5.34353024 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.90890106 |
| 10 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.90890106 |
| 11 | translational elongation (GO:0006414) | 4.85791002 |
| 12 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.83019485 |
| 13 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.70921446 |
| 14 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.69104842 |
| 15 | cotranslational protein targeting to membrane (GO:0006613) | 4.60821888 |
| 16 | protein targeting to ER (GO:0045047) | 4.59970958 |
| 17 | ribosomal small subunit biogenesis (GO:0042274) | 4.45680327 |
| 18 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.37908443 |
| 19 | protein localization to endoplasmic reticulum (GO:0070972) | 4.32782124 |
| 20 | maturation of SSU-rRNA (GO:0030490) | 4.18526027 |
| 21 | viral life cycle (GO:0019058) | 4.04015862 |
| 22 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.04005778 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.03607055 |
| 24 | cellular protein complex disassembly (GO:0043624) | 4.01280763 |
| 25 | ribosomal large subunit biogenesis (GO:0042273) | 3.91030360 |
| 26 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.84130538 |
| 27 | respiratory electron transport chain (GO:0022904) | 3.81797072 |
| 28 | translational initiation (GO:0006413) | 3.80727619 |
| 29 | electron transport chain (GO:0022900) | 3.78542829 |
| 30 | chaperone-mediated protein transport (GO:0072321) | 3.69425958 |
| 31 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.59018152 |
| 32 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.58303877 |
| 33 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.58303877 |
| 34 | protein complex biogenesis (GO:0070271) | 3.54524204 |
| 35 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.54210298 |
| 36 | protein neddylation (GO:0045116) | 3.52483105 |
| 37 | metallo-sulfur cluster assembly (GO:0031163) | 3.43828319 |
| 38 | iron-sulfur cluster assembly (GO:0016226) | 3.43828319 |
| 39 | proteasome assembly (GO:0043248) | 3.42562123 |
| 40 | translation (GO:0006412) | 3.37766094 |
| 41 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.31719867 |
| 42 | NADH dehydrogenase complex assembly (GO:0010257) | 3.31719867 |
| 43 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.31719867 |
| 44 | actin nucleation (GO:0045010) | 3.30171153 |
| 45 | response to pheromone (GO:0019236) | 3.27026123 |
| 46 | protein complex disassembly (GO:0043241) | 3.26128678 |
| 47 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.23419989 |
| 48 | behavioral response to nicotine (GO:0035095) | 3.16603256 |
| 49 | macromolecular complex disassembly (GO:0032984) | 3.13541420 |
| 50 | GTP biosynthetic process (GO:0006183) | 3.12808342 |
| 51 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.11804906 |
| 52 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.11638414 |
| 53 | ncRNA 3-end processing (GO:0043628) | 3.10446672 |
| 54 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.07159941 |
| 55 | sequestering of actin monomers (GO:0042989) | 3.03251003 |
| 56 | base-excision repair, AP site formation (GO:0006285) | 3.01316130 |
| 57 | pseudouridine synthesis (GO:0001522) | 2.99794464 |
| 58 | cellular component biogenesis (GO:0044085) | 2.96710805 |
| 59 | positive regulation of B cell differentiation (GO:0045579) | 2.96104283 |
| 60 | ubiquinone biosynthetic process (GO:0006744) | 2.96078209 |
| 61 | respiratory chain complex IV assembly (GO:0008535) | 2.94158587 |
| 62 | protein targeting to membrane (GO:0006612) | 2.92786243 |
| 63 | negative regulation of T cell apoptotic process (GO:0070233) | 2.92376058 |
| 64 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.92168708 |
| 65 | deoxyribonucleotide catabolic process (GO:0009264) | 2.89664159 |
| 66 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.88111717 |
| 67 | platelet dense granule organization (GO:0060155) | 2.87797133 |
| 68 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.85960729 |
| 69 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.81564313 |
| 70 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.81435346 |
| 71 | regulation of activation of Janus kinase activity (GO:0010533) | 2.80756049 |
| 72 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.80580079 |
| 73 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.80224884 |
| 74 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.78972692 |
| 75 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.78742230 |
| 76 | cytolysis (GO:0019835) | 2.77897102 |
| 77 | deoxyribose phosphate catabolic process (GO:0046386) | 2.77132599 |
| 78 | cytochrome complex assembly (GO:0017004) | 2.75761072 |
| 79 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.75012172 |
| 80 | UTP biosynthetic process (GO:0006228) | 2.74646844 |
| 81 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.73500507 |
| 82 | positive regulation of T cell apoptotic process (GO:0070234) | 2.72800140 |
| 83 | hydrogen ion transmembrane transport (GO:1902600) | 2.72433873 |
| 84 | axoneme assembly (GO:0035082) | 2.68905305 |
| 85 | UTP metabolic process (GO:0046051) | 2.68878537 |
| 86 | ATP biosynthetic process (GO:0006754) | 2.68287750 |
| 87 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.67511545 |
| 88 | purine nucleotide salvage (GO:0032261) | 2.62697375 |
| 89 | aggressive behavior (GO:0002118) | 2.61513440 |
| 90 | mRNA catabolic process (GO:0006402) | 2.60248179 |
| 91 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.60130720 |
| 92 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.58357093 |
| 93 | ubiquinone metabolic process (GO:0006743) | 2.57958275 |
| 94 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.57039726 |
| 95 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.56909223 |
| 96 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.56909223 |
| 97 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.56909223 |
| 98 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.55549445 |
| 99 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.55549445 |
| 100 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.54743844 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.67377225 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.58106715 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.30506845 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.16098350 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.06863156 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.72172715 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.72001535 |
| 8 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.68143197 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.67779416 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.63526687 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.58791947 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.51299925 |
| 13 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.47315430 |
| 14 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.45487579 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.36428927 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.33368847 |
| 17 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.26578880 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.14083443 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.04227694 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.02018043 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00709203 |
| 22 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.87252169 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.70416717 |
| 24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.69738477 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.65554169 |
| 26 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.60557071 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.59621936 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.59198454 |
| 29 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57999151 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.57435273 |
| 31 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.57344796 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.53982306 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.51359111 |
| 34 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.46875909 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43986982 |
| 36 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.42355636 |
| 37 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41683713 |
| 38 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.40839616 |
| 39 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.40839616 |
| 40 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.40835309 |
| 41 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.36185751 |
| 42 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.36143228 |
| 43 | MYB_26560356_Chip-Seq_TH2_Human | 1.35978784 |
| 44 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.35463311 |
| 45 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.34601720 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.33964275 |
| 47 | AR_20517297_ChIP-Seq_VCAP_Human | 1.33850894 |
| 48 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.33480962 |
| 49 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.32908241 |
| 50 | NCOR_22424771_ChIP-Seq_293T_Human | 1.32885697 |
| 51 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.31739313 |
| 52 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.29629782 |
| 53 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.29474713 |
| 54 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.24593303 |
| 55 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.23951209 |
| 56 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.23213409 |
| 57 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.22864638 |
| 58 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.21306377 |
| 59 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19618579 |
| 60 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.19019553 |
| 61 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.14770193 |
| 62 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.14029565 |
| 63 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.13237289 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.12993419 |
| 65 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.12906834 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.12905242 |
| 67 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.12480102 |
| 68 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.11890437 |
| 69 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.10191436 |
| 70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09445208 |
| 71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09445208 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08898935 |
| 73 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.08074375 |
| 74 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.08022035 |
| 75 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08011427 |
| 76 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.07291119 |
| 77 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.07268646 |
| 78 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.06522912 |
| 79 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.06219292 |
| 80 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.04477213 |
| 81 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.03958547 |
| 82 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.03470914 |
| 83 | GATA3_26560356_Chip-Seq_TH2_Human | 1.03234906 |
| 84 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.03181827 |
| 85 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02758799 |
| 86 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.02129445 |
| 87 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.01274349 |
| 88 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.00951558 |
| 89 | P300_27268052_Chip-Seq_Bcells_Human | 0.98915049 |
| 90 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.98654039 |
| 91 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.98189871 |
| 92 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97005921 |
| 93 | ERA_21632823_ChIP-Seq_H3396_Human | 0.96247991 |
| 94 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.95542110 |
| 95 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.93102351 |
| 96 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.90846811 |
| 97 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.89534028 |
| 98 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.89351979 |
| 99 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.89259579 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.87555892 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.67348879 |
| 2 | MP0005671_abnormal_response_to | 3.79893473 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.10653568 |
| 4 | MP0005646_abnormal_pituitary_gland | 2.32619037 |
| 5 | MP0001873_stomach_inflammation | 2.11302723 |
| 6 | MP0003878_abnormal_ear_physiology | 2.11041091 |
| 7 | MP0005377_hearing/vestibular/ear_phenot | 2.11041091 |
| 8 | MP0009785_altered_susceptibility_to | 2.08025884 |
| 9 | MP0009333_abnormal_splenocyte_physiolog | 2.06052552 |
| 10 | MP0001835_abnormal_antigen_presentation | 2.05456756 |
| 11 | MP0004147_increased_porphyrin_level | 2.04174616 |
| 12 | MP0002102_abnormal_ear_morphology | 1.96186268 |
| 13 | MP0005645_abnormal_hypothalamus_physiol | 1.88141514 |
| 14 | MP0003646_muscle_fatigue | 1.87890673 |
| 15 | MP0001764_abnormal_homeostasis | 1.86170829 |
| 16 | MP0002160_abnormal_reproductive_system | 1.80234159 |
| 17 | MP0003763_abnormal_thymus_physiology | 1.80061529 |
| 18 | MP0008872_abnormal_physiological_respon | 1.77687432 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 1.76188019 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.75651739 |
| 21 | MP0008877_abnormal_DNA_methylation | 1.74383702 |
| 22 | MP0002837_dystrophic_cardiac_calcinosis | 1.69639857 |
| 23 | MP0006072_abnormal_retinal_apoptosis | 1.67356071 |
| 24 | MP0000372_irregular_coat_pigmentation | 1.61278627 |
| 25 | MP0001800_abnormal_humoral_immune | 1.60105983 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.57153469 |
| 27 | MP0005389_reproductive_system_phenotype | 1.57126113 |
| 28 | MP0001485_abnormal_pinna_reflex | 1.56184063 |
| 29 | MP0005551_abnormal_eye_electrophysiolog | 1.55855353 |
| 30 | MP0002736_abnormal_nociception_after | 1.55218659 |
| 31 | MP0008995_early_reproductive_senescence | 1.52366292 |
| 32 | MP0001968_abnormal_touch/_nociception | 1.50697197 |
| 33 | MP0001188_hyperpigmentation | 1.46767809 |
| 34 | MP0002095_abnormal_skin_pigmentation | 1.44898805 |
| 35 | MP0002163_abnormal_gland_morphology | 1.41151219 |
| 36 | MP0005000_abnormal_immune_tolerance | 1.38043306 |
| 37 | MP0004885_abnormal_endolymph | 1.37594490 |
| 38 | MP0003806_abnormal_nucleotide_metabolis | 1.34604328 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.34480129 |
| 40 | MP0002876_abnormal_thyroid_physiology | 1.34202823 |
| 41 | MP0002420_abnormal_adaptive_immunity | 1.32675517 |
| 42 | MP0001905_abnormal_dopamine_level | 1.32256094 |
| 43 | MP0001790_abnormal_immune_system | 1.31229082 |
| 44 | MP0005387_immune_system_phenotype | 1.31229082 |
| 45 | MP0003567_abnormal_fetal_cardiomyocyte | 1.30789150 |
| 46 | MP0002723_abnormal_immune_serum | 1.30237414 |
| 47 | MP0002653_abnormal_ependyma_morphology | 1.29086231 |
| 48 | MP0001819_abnormal_immune_cell | 1.27837873 |
| 49 | MP0002638_abnormal_pupillary_reflex | 1.26763182 |
| 50 | MP0003786_premature_aging | 1.26323439 |
| 51 | MP0002132_abnormal_respiratory_system | 1.24461740 |
| 52 | MP0005025_abnormal_response_to | 1.24338792 |
| 53 | MP0001919_abnormal_reproductive_system | 1.23064784 |
| 54 | MP0002166_altered_tumor_susceptibility | 1.21344308 |
| 55 | MP0004142_abnormal_muscle_tone | 1.21020997 |
| 56 | MP0008875_abnormal_xenobiotic_pharmacok | 1.19771721 |
| 57 | MP0000678_abnormal_parathyroid_gland | 1.16563280 |
| 58 | MP0008789_abnormal_olfactory_epithelium | 1.15621097 |
| 59 | MP0002398_abnormal_bone_marrow | 1.15073103 |
| 60 | MP0000716_abnormal_immune_system | 1.13525153 |
| 61 | MP0000685_abnormal_immune_system | 1.11525515 |
| 62 | MP0006276_abnormal_autonomic_nervous | 1.11118004 |
| 63 | MP0003787_abnormal_imprinting | 1.10943741 |
| 64 | MP0001986_abnormal_taste_sensitivity | 1.09260656 |
| 65 | MP0002006_tumorigenesis | 1.08635695 |
| 66 | MP0010155_abnormal_intestine_physiology | 1.01216236 |
| 67 | MP0005253_abnormal_eye_physiology | 0.99718333 |
| 68 | MP0002452_abnormal_antigen_presenting | 0.98790196 |
| 69 | MP0002272_abnormal_nervous_system | 0.98244741 |
| 70 | MP0000689_abnormal_spleen_morphology | 0.97562840 |
| 71 | MP0003123_paternal_imprinting | 0.94990625 |
| 72 | MP0001293_anophthalmia | 0.93196828 |
| 73 | MP0004742_abnormal_vestibular_system | 0.91838238 |
| 74 | MP0001529_abnormal_vocalization | 0.91530579 |
| 75 | MP0000703_abnormal_thymus_morphology | 0.91442081 |
| 76 | MP0005636_abnormal_mineral_homeostasis | 0.91403194 |
| 77 | MP0000049_abnormal_middle_ear | 0.90657460 |
| 78 | MP0002429_abnormal_blood_cell | 0.90140887 |
| 79 | MP0006036_abnormal_mitochondrial_physio | 0.90073965 |
| 80 | MP0002405_respiratory_system_inflammati | 0.87806344 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.87240175 |
| 82 | MP0002722_abnormal_immune_system | 0.87130529 |
| 83 | MP0001348_abnormal_lacrimal_gland | 0.85295088 |
| 84 | MP0005410_abnormal_fertilization | 0.84879716 |
| 85 | MP0005379_endocrine/exocrine_gland_phen | 0.84247734 |
| 86 | MP0000631_abnormal_neuroendocrine_gland | 0.84168447 |
| 87 | MP0003866_abnormal_defecation | 0.82738308 |
| 88 | MP0005464_abnormal_platelet_physiology | 0.81438460 |
| 89 | MP0004145_abnormal_muscle_electrophysio | 0.80450778 |
| 90 | MP0001963_abnormal_hearing_physiology | 0.79816282 |
| 91 | MP0005085_abnormal_gallbladder_physiolo | 0.78925296 |
| 92 | MP0005360_urolithiasis | 0.78690323 |
| 93 | MP0001845_abnormal_inflammatory_respons | 0.76918362 |
| 94 | MP0001661_extended_life_span | 0.75989846 |
| 95 | MP0003880_abnormal_central_pattern | 0.73902144 |
| 96 | MP0000026_abnormal_inner_ear | 0.73830445 |
| 97 | MP0001663_abnormal_digestive_system | 0.71951009 |
| 98 | MP0000681_abnormal_thyroid_gland | 0.71832207 |
| 99 | MP0002933_joint_inflammation | 0.71764470 |
| 100 | MP0002693_abnormal_pancreas_physiology | 0.70822775 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.03550451 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.00146209 |
| 3 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.80627835 |
| 4 | Congenital stationary night blindness (HP:0007642) | 3.75485019 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 3.72210968 |
| 6 | Reticulocytopenia (HP:0001896) | 3.67961470 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.64854384 |
| 8 | Abnormality of B cell number (HP:0010975) | 3.57744449 |
| 9 | Increased CSF lactate (HP:0002490) | 3.43741137 |
| 10 | Aplastic anemia (HP:0001915) | 3.39367195 |
| 11 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.36265237 |
| 12 | B lymphocytopenia (HP:0010976) | 3.33093843 |
| 13 | Acute encephalopathy (HP:0006846) | 3.30332346 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.29574646 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.29157086 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 3.28525355 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.24689950 |
| 18 | Progressive macrocephaly (HP:0004481) | 3.21377153 |
| 19 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.21067054 |
| 20 | Severe combined immunodeficiency (HP:0004430) | 3.15843159 |
| 21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.09945224 |
| 22 | Hepatic necrosis (HP:0002605) | 2.99756922 |
| 23 | Macrocytic anemia (HP:0001972) | 2.92033011 |
| 24 | Hypoproteinemia (HP:0003075) | 2.87788010 |
| 25 | IgG deficiency (HP:0004315) | 2.85671542 |
| 26 | Cerebral edema (HP:0002181) | 2.82139149 |
| 27 | Pancreatic cysts (HP:0001737) | 2.80944104 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.75641883 |
| 29 | Abnormal number of erythroid precursors (HP:0012131) | 2.73499851 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.73201287 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.73201287 |
| 32 | True hermaphroditism (HP:0010459) | 2.70202509 |
| 33 | Increased muscle lipid content (HP:0009058) | 2.68034451 |
| 34 | Constricted visual fields (HP:0001133) | 2.65023192 |
| 35 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.63019349 |
| 36 | Exertional dyspnea (HP:0002875) | 2.61723152 |
| 37 | Asplenia (HP:0001746) | 2.60502905 |
| 38 | T lymphocytopenia (HP:0005403) | 2.57996240 |
| 39 | Abolished electroretinogram (ERG) (HP:0000550) | 2.57381222 |
| 40 | Pallor (HP:0000980) | 2.56548941 |
| 41 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.54812312 |
| 42 | Optic disc pallor (HP:0000543) | 2.53228284 |
| 43 | Thyroiditis (HP:0100646) | 2.52369272 |
| 44 | Abnormality of T cell number (HP:0011839) | 2.51412097 |
| 45 | Combined immunodeficiency (HP:0005387) | 2.41347295 |
| 46 | Increased serum lactate (HP:0002151) | 2.41222655 |
| 47 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.38786884 |
| 48 | Attenuation of retinal blood vessels (HP:0007843) | 2.37059404 |
| 49 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.33784372 |
| 50 | 3-Methylglutaconic aciduria (HP:0003535) | 2.33228080 |
| 51 | Absent/shortened dynein arms (HP:0200106) | 2.33054745 |
| 52 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.33054745 |
| 53 | Glycosuria (HP:0003076) | 2.32591490 |
| 54 | Abnormality of urine glucose concentration (HP:0011016) | 2.32591490 |
| 55 | Medial flaring of the eyebrow (HP:0010747) | 2.32327620 |
| 56 | Reduced antithrombin III activity (HP:0001976) | 2.31897777 |
| 57 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.31403683 |
| 58 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.31403683 |
| 59 | Agammaglobulinemia (HP:0004432) | 2.28752219 |
| 60 | Hyperglycinemia (HP:0002154) | 2.28256717 |
| 61 | Stenosis of the external auditory canal (HP:0000402) | 2.28168312 |
| 62 | Lactic acidosis (HP:0003128) | 2.28071653 |
| 63 | Decreased central vision (HP:0007663) | 2.23902429 |
| 64 | Increased IgM level (HP:0003496) | 2.23507192 |
| 65 | Abnormal ciliary motility (HP:0012262) | 2.19654066 |
| 66 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.17787548 |
| 67 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.17787548 |
| 68 | Chronic sinusitis (HP:0011109) | 2.16989075 |
| 69 | Panhypogammaglobulinemia (HP:0003139) | 2.14871017 |
| 70 | Lethargy (HP:0001254) | 2.13741921 |
| 71 | Hyperphosphaturia (HP:0003109) | 2.11679905 |
| 72 | Absent thumb (HP:0009777) | 2.11611008 |
| 73 | Pancytopenia (HP:0001876) | 2.11285382 |
| 74 | Abnormality of DNA repair (HP:0003254) | 2.10282774 |
| 75 | Autoimmune hemolytic anemia (HP:0001890) | 2.09101439 |
| 76 | Abnormality of renal resorption (HP:0011038) | 2.05837544 |
| 77 | Methylmalonic acidemia (HP:0002912) | 2.05528479 |
| 78 | Abnormality of the renal collecting system (HP:0004742) | 2.04803654 |
| 79 | Respiratory difficulties (HP:0002880) | 2.03052255 |
| 80 | Congenital primary aphakia (HP:0007707) | 2.02241036 |
| 81 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.01772325 |
| 82 | Pendular nystagmus (HP:0012043) | 2.00470544 |
| 83 | Abnormality of eosinophils (HP:0001879) | 1.98409651 |
| 84 | Hypoplasia of the thymus (HP:0000778) | 1.97581513 |
| 85 | Abnormal protein glycosylation (HP:0012346) | 1.97167593 |
| 86 | Abnormal glycosylation (HP:0012345) | 1.97167593 |
| 87 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.97167593 |
| 88 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.97167593 |
| 89 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.97011779 |
| 90 | Gait imbalance (HP:0002141) | 1.95768622 |
| 91 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.95623165 |
| 92 | Nephronophthisis (HP:0000090) | 1.95200791 |
| 93 | Nephrogenic diabetes insipidus (HP:0009806) | 1.93949558 |
| 94 | Methylmalonic aciduria (HP:0012120) | 1.93430379 |
| 95 | Exercise intolerance (HP:0003546) | 1.92674508 |
| 96 | Type 2 muscle fiber atrophy (HP:0003554) | 1.91537536 |
| 97 | Abnormality of T cells (HP:0002843) | 1.91027344 |
| 98 | Generalized aminoaciduria (HP:0002909) | 1.88256829 |
| 99 | Dyschromatopsia (HP:0007641) | 1.87471091 |
| 100 | Abnormality of macular pigmentation (HP:0008002) | 1.83514178 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 3.99083167 |
| 2 | TESK2 | 3.86428904 |
| 3 | BCKDK | 3.37942888 |
| 4 | TXK | 3.08905874 |
| 5 | VRK2 | 3.02750043 |
| 6 | CDK19 | 2.89907350 |
| 7 | GRK1 | 2.74142007 |
| 8 | ZAK | 2.68779595 |
| 9 | MAP4K1 | 2.64458755 |
| 10 | ADRBK2 | 2.39549643 |
| 11 | MAP3K11 | 2.33768123 |
| 12 | TAOK3 | 2.08171339 |
| 13 | MAP4K2 | 2.04012690 |
| 14 | STK16 | 1.90134341 |
| 15 | TIE1 | 1.86492375 |
| 16 | NUAK1 | 1.82928657 |
| 17 | VRK1 | 1.81685987 |
| 18 | TLK1 | 1.76772549 |
| 19 | ITK | 1.65274579 |
| 20 | PASK | 1.63885235 |
| 21 | TAF1 | 1.48363305 |
| 22 | TEC | 1.46859067 |
| 23 | SCYL2 | 1.32089995 |
| 24 | SYK | 1.30088293 |
| 25 | MAP3K12 | 1.26844809 |
| 26 | WNK4 | 1.21406458 |
| 27 | PINK1 | 1.18676322 |
| 28 | DYRK2 | 1.18636477 |
| 29 | GRK6 | 1.17387291 |
| 30 | PRKCQ | 1.17248209 |
| 31 | LIMK1 | 1.16322996 |
| 32 | BMPR1B | 1.10652122 |
| 33 | PIK3CA | 0.99953096 |
| 34 | TNK2 | 0.99151159 |
| 35 | NME2 | 0.98582338 |
| 36 | BTK | 0.96334632 |
| 37 | EIF2AK3 | 0.93744362 |
| 38 | PLK4 | 0.91655544 |
| 39 | NME1 | 0.91456893 |
| 40 | IKBKE | 0.85727241 |
| 41 | FRK | 0.84750587 |
| 42 | PBK | 0.83984759 |
| 43 | ADRBK1 | 0.83779879 |
| 44 | WNK3 | 0.83305552 |
| 45 | LCK | 0.82341824 |
| 46 | MAP2K6 | 0.80928506 |
| 47 | INSRR | 0.79675020 |
| 48 | DAPK1 | 0.79057594 |
| 49 | RPS6KA4 | 0.77840612 |
| 50 | ACVR1B | 0.77606903 |
| 51 | MST4 | 0.76898410 |
| 52 | PIM2 | 0.73778973 |
| 53 | FES | 0.73070349 |
| 54 | AURKA | 0.69947591 |
| 55 | RPS6KA5 | 0.69367274 |
| 56 | MUSK | 0.68441858 |
| 57 | PIK3CG | 0.67440142 |
| 58 | LYN | 0.64388712 |
| 59 | KIT | 0.62539759 |
| 60 | CDC7 | 0.62103893 |
| 61 | PIM1 | 0.61734379 |
| 62 | MAP2K7 | 0.60565081 |
| 63 | IKBKB | 0.60375680 |
| 64 | STK39 | 0.59309908 |
| 65 | CSNK1G1 | 0.57950220 |
| 66 | DAPK3 | 0.55355647 |
| 67 | DAPK2 | 0.53365947 |
| 68 | CSNK2A2 | 0.52976260 |
| 69 | OBSCN | 0.52532924 |
| 70 | ZAP70 | 0.51862333 |
| 71 | PRKCH | 0.51203013 |
| 72 | CSF1R | 0.50875371 |
| 73 | CSNK1G3 | 0.50547463 |
| 74 | CSNK2A1 | 0.49868682 |
| 75 | CDK3 | 0.49683580 |
| 76 | MAP3K5 | 0.49411339 |
| 77 | GRK7 | 0.47987258 |
| 78 | MAPKAPK3 | 0.46839462 |
| 79 | PLK1 | 0.46185428 |
| 80 | PRKACA | 0.44391879 |
| 81 | PRKCA | 0.44036899 |
| 82 | LRRK2 | 0.43810316 |
| 83 | NLK | 0.43451432 |
| 84 | RPS6KB2 | 0.40631693 |
| 85 | CSNK1G2 | 0.40286656 |
| 86 | BUB1 | 0.38853370 |
| 87 | AURKB | 0.38356961 |
| 88 | OXSR1 | 0.37915494 |
| 89 | RPS6KA6 | 0.37074675 |
| 90 | PRKCD | 0.35831581 |
| 91 | CSK | 0.35525187 |
| 92 | ATR | 0.33811953 |
| 93 | JAK3 | 0.33479242 |
| 94 | MAP3K4 | 0.33114780 |
| 95 | PRKCG | 0.31754189 |
| 96 | TESK1 | 0.30745981 |
| 97 | CSNK1A1 | 0.30744822 |
| 98 | PRKCE | 0.30478293 |
| 99 | TBK1 | 0.29690716 |
| 100 | IGF1R | 0.29637361 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.91456532 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.83264987 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.82009242 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.80855181 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.18877369 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.39510765 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.14430616 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.06214644 |
| 9 | Phototransduction_Homo sapiens_hsa04744 | 2.03598110 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.98580157 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.85748688 |
| 12 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.81597869 |
| 13 | Allograft rejection_Homo sapiens_hsa05330 | 1.79415333 |
| 14 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.73887883 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.71082687 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.67284766 |
| 17 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.65225871 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.59045558 |
| 19 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.55428753 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.54303481 |
| 21 | Protein export_Homo sapiens_hsa03060 | 1.53862961 |
| 22 | Homologous recombination_Homo sapiens_hsa03440 | 1.50726278 |
| 23 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.50428753 |
| 24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.48424156 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.47493508 |
| 26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.43940567 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.41467875 |
| 28 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.40093355 |
| 29 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.33685367 |
| 30 | Peroxisome_Homo sapiens_hsa04146 | 1.30117584 |
| 31 | RNA degradation_Homo sapiens_hsa03018 | 1.22842674 |
| 32 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.20437747 |
| 33 | DNA replication_Homo sapiens_hsa03030 | 1.08710927 |
| 34 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.08278779 |
| 35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.06671034 |
| 36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.05145310 |
| 37 | Base excision repair_Homo sapiens_hsa03410 | 1.04346461 |
| 38 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.02958422 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.02211819 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.00582161 |
| 41 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.99965125 |
| 42 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.95741506 |
| 43 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.95427523 |
| 44 | Retinol metabolism_Homo sapiens_hsa00830 | 0.94428923 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92081319 |
| 46 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.91908689 |
| 47 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.91763209 |
| 48 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.88444513 |
| 49 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.86898471 |
| 50 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.86080927 |
| 51 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.85740380 |
| 52 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.84324590 |
| 53 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.83888737 |
| 54 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.82915618 |
| 55 | Mismatch repair_Homo sapiens_hsa03430 | 0.81931300 |
| 56 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.80373433 |
| 57 | Basal transcription factors_Homo sapiens_hsa03022 | 0.76333993 |
| 58 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74002429 |
| 59 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.73375286 |
| 60 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73088782 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71946788 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.71829986 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.71825598 |
| 64 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.71603695 |
| 65 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.71517619 |
| 66 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.67737516 |
| 67 | RNA transport_Homo sapiens_hsa03013 | 0.66407755 |
| 68 | Spliceosome_Homo sapiens_hsa03040 | 0.63685524 |
| 69 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.62210052 |
| 70 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61675736 |
| 71 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60473721 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.57488495 |
| 73 | Sulfur relay system_Homo sapiens_hsa04122 | 0.57279170 |
| 74 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.56866667 |
| 75 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.56352672 |
| 76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53893633 |
| 77 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.52631474 |
| 78 | Nicotine addiction_Homo sapiens_hsa05033 | 0.51730936 |
| 79 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51565137 |
| 80 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.47981837 |
| 81 | Taste transduction_Homo sapiens_hsa04742 | 0.43732751 |
| 82 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.43280120 |
| 83 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41612950 |
| 84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.40740521 |
| 85 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.39636703 |
| 86 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.38369012 |
| 87 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34342105 |
| 88 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.33892671 |
| 89 | Measles_Homo sapiens_hsa05162 | 0.33080153 |
| 90 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.31137910 |
| 91 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.30676149 |
| 92 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.28701943 |
| 93 | Malaria_Homo sapiens_hsa05144 | 0.27203958 |
| 94 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.25598118 |
| 95 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.24891869 |
| 96 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.23693345 |
| 97 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.23179495 |
| 98 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.20801139 |
| 99 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.20199860 |
| 100 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.18796392 |

