

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 8.12519489 |
| 2 | DNA deamination (GO:0045006) | 6.11758307 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.35288496 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.24060895 |
| 5 | sequestering of actin monomers (GO:0042989) | 5.20850303 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 5.00521903 |
| 7 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.00521903 |
| 8 | cytidine metabolic process (GO:0046087) | 4.84202186 |
| 9 | cytidine catabolic process (GO:0006216) | 4.84202186 |
| 10 | cytidine deamination (GO:0009972) | 4.84202186 |
| 11 | viral transcription (GO:0019083) | 4.83323336 |
| 12 | translational termination (GO:0006415) | 4.69059502 |
| 13 | translational elongation (GO:0006414) | 4.29789224 |
| 14 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.21874479 |
| 15 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.17896236 |
| 16 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.17896236 |
| 17 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.13974973 |
| 18 | cotranslational protein targeting to membrane (GO:0006613) | 4.09182992 |
| 19 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.08913793 |
| 20 | NADH dehydrogenase complex assembly (GO:0010257) | 4.06081468 |
| 21 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.06081468 |
| 22 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.06081468 |
| 23 | protein targeting to ER (GO:0045047) | 4.04301974 |
| 24 | protein neddylation (GO:0045116) | 4.03189106 |
| 25 | protein complex biogenesis (GO:0070271) | 4.01191693 |
| 26 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.93005876 |
| 27 | respiratory electron transport chain (GO:0022904) | 3.84911083 |
| 28 | behavioral response to nicotine (GO:0035095) | 3.84715849 |
| 29 | electron transport chain (GO:0022900) | 3.82487336 |
| 30 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.82269442 |
| 31 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.81711291 |
| 32 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.81578129 |
| 33 | ribosomal large subunit biogenesis (GO:0042273) | 3.78378195 |
| 34 | protein localization to endoplasmic reticulum (GO:0070972) | 3.77585956 |
| 35 | pseudouridine synthesis (GO:0001522) | 3.74610968 |
| 36 | ribosomal small subunit biogenesis (GO:0042274) | 3.66281241 |
| 37 | cellular ketone body metabolic process (GO:0046950) | 3.59437935 |
| 38 | ncRNA 3-end processing (GO:0043628) | 3.58934689 |
| 39 | actin nucleation (GO:0045010) | 3.57780638 |
| 40 | cellular protein complex disassembly (GO:0043624) | 3.51416354 |
| 41 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.49062913 |
| 42 | viral life cycle (GO:0019058) | 3.47974089 |
| 43 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.46060047 |
| 44 | translational initiation (GO:0006413) | 3.42081800 |
| 45 | maturation of SSU-rRNA (GO:0030490) | 3.40186045 |
| 46 | chaperone-mediated protein transport (GO:0072321) | 3.38099208 |
| 47 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.33874536 |
| 48 | purine nucleotide salvage (GO:0032261) | 3.26991440 |
| 49 | ketone body metabolic process (GO:1902224) | 3.24228402 |
| 50 | translation (GO:0006412) | 3.19896738 |
| 51 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.11147119 |
| 52 | cellular component biogenesis (GO:0044085) | 2.95975651 |
| 53 | regulation of appetite (GO:0032098) | 2.90844562 |
| 54 | negative regulation of response to food (GO:0032096) | 2.88206052 |
| 55 | negative regulation of appetite (GO:0032099) | 2.88206052 |
| 56 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.84626187 |
| 57 | aldehyde catabolic process (GO:0046185) | 2.84250203 |
| 58 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.83874108 |
| 59 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.82891044 |
| 60 | protein complex disassembly (GO:0043241) | 2.82037321 |
| 61 | drinking behavior (GO:0042756) | 2.80445733 |
| 62 | hydrogen ion transmembrane transport (GO:1902600) | 2.79536422 |
| 63 | piRNA metabolic process (GO:0034587) | 2.77157673 |
| 64 | proton transport (GO:0015992) | 2.75485967 |
| 65 | proteasome assembly (GO:0043248) | 2.74745441 |
| 66 | hydrogen transport (GO:0006818) | 2.73969363 |
| 67 | macromolecular complex disassembly (GO:0032984) | 2.73685834 |
| 68 | adenosine metabolic process (GO:0046085) | 2.73482866 |
| 69 | protein-cofactor linkage (GO:0018065) | 2.72739920 |
| 70 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.71112652 |
| 71 | S-adenosylmethionine metabolic process (GO:0046500) | 2.70702075 |
| 72 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.67238434 |
| 73 | ATP biosynthetic process (GO:0006754) | 2.65968993 |
| 74 | metallo-sulfur cluster assembly (GO:0031163) | 2.63823434 |
| 75 | iron-sulfur cluster assembly (GO:0016226) | 2.63823434 |
| 76 | protein polyglutamylation (GO:0018095) | 2.61745497 |
| 77 | nonmotile primary cilium assembly (GO:0035058) | 2.61679045 |
| 78 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.59455193 |
| 79 | positive thymic T cell selection (GO:0045059) | 2.59224557 |
| 80 | negative regulation of oxidoreductase activity (GO:0051354) | 2.59169195 |
| 81 | platelet dense granule organization (GO:0060155) | 2.59023581 |
| 82 | cytochrome complex assembly (GO:0017004) | 2.57051170 |
| 83 | mannosylation (GO:0097502) | 2.55520921 |
| 84 | protein deneddylation (GO:0000338) | 2.54536239 |
| 85 | mRNA catabolic process (GO:0006402) | 2.53652035 |
| 86 | respiratory chain complex IV assembly (GO:0008535) | 2.53413295 |
| 87 | protein targeting to membrane (GO:0006612) | 2.53217755 |
| 88 | deoxyribonucleotide catabolic process (GO:0009264) | 2.50651901 |
| 89 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.49731362 |
| 90 | positive T cell selection (GO:0043368) | 2.48035176 |
| 91 | DNA demethylation (GO:0080111) | 2.47872646 |
| 92 | DNA dealkylation (GO:0035510) | 2.47769709 |
| 93 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.47383905 |
| 94 | rRNA processing (GO:0006364) | 2.46254848 |
| 95 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.46248449 |
| 96 | response to interferon-beta (GO:0035456) | 2.45865788 |
| 97 | rRNA metabolic process (GO:0016072) | 2.45372154 |
| 98 | base-excision repair, AP site formation (GO:0006285) | 2.44004934 |
| 99 | deoxyribose phosphate catabolic process (GO:0046386) | 2.43834251 |
| 100 | protein K6-linked ubiquitination (GO:0085020) | 2.39493818 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.40391487 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.39608130 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.34182054 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.33907508 |
| 5 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.22168927 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.12693383 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.77141667 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.65111911 |
| 9 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.60857356 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.59178298 |
| 11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.44026009 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.41903081 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.38351980 |
| 14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.33186027 |
| 15 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.19141032 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.14426405 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.06508279 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.02705640 |
| 19 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.94400484 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.93986618 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.93017000 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.90743373 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.73281282 |
| 24 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.71336904 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.71285674 |
| 26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.69102837 |
| 27 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.61161912 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.59835312 |
| 29 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.58283292 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.58025602 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.57410241 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.53734444 |
| 33 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.53589232 |
| 34 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.51585336 |
| 35 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.50231842 |
| 36 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.48861833 |
| 37 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.47906897 |
| 38 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.47906897 |
| 39 | AR_20517297_ChIP-Seq_VCAP_Human | 1.47860609 |
| 40 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.43908732 |
| 41 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.40309689 |
| 42 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.38275536 |
| 43 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.36292760 |
| 44 | NCOR_22424771_ChIP-Seq_293T_Human | 1.35764917 |
| 45 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.33241846 |
| 46 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.31949795 |
| 47 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.31835850 |
| 48 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.31165375 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.31043945 |
| 50 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.30227398 |
| 51 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.30110414 |
| 52 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.28000580 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.26579320 |
| 54 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.25450199 |
| 55 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25297842 |
| 56 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.22935039 |
| 57 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.22705557 |
| 58 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.21722595 |
| 59 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20109656 |
| 60 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.17685799 |
| 61 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.17252881 |
| 62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16573774 |
| 63 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.16289473 |
| 64 | P300_19829295_ChIP-Seq_ESCs_Human | 1.16132330 |
| 65 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.15805658 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.14575534 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.14575534 |
| 68 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.13726290 |
| 69 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.11371371 |
| 70 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11354631 |
| 71 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.09853514 |
| 72 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.07361182 |
| 73 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07170860 |
| 74 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07170860 |
| 75 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.04201039 |
| 76 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.03136067 |
| 77 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01821833 |
| 78 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.01574165 |
| 79 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.00854077 |
| 80 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00436380 |
| 81 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.00422469 |
| 82 | MYB_26560356_Chip-Seq_TH2_Human | 0.99203859 |
| 83 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.99189029 |
| 84 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.99112378 |
| 85 | GATA3_26560356_Chip-Seq_TH2_Human | 0.96999296 |
| 86 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.95519909 |
| 87 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.95012590 |
| 88 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.93629676 |
| 89 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.91843579 |
| 90 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.91735363 |
| 91 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.91586049 |
| 92 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.91328061 |
| 93 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.89886721 |
| 94 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.89627069 |
| 95 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.88824133 |
| 96 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.88064441 |
| 97 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.88019747 |
| 98 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.87829246 |
| 99 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.86874138 |
| 100 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.86351481 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.10655103 |
| 2 | MP0005084_abnormal_gallbladder_morpholo | 3.15080025 |
| 3 | MP0008877_abnormal_DNA_methylation | 2.68877134 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.64738811 |
| 5 | MP0005645_abnormal_hypothalamus_physiol | 2.52625976 |
| 6 | MP0005671_abnormal_response_to | 2.49686927 |
| 7 | MP0002837_dystrophic_cardiac_calcinosis | 2.49150009 |
| 8 | MP0005646_abnormal_pituitary_gland | 2.42318403 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.40108090 |
| 10 | MP0002102_abnormal_ear_morphology | 2.31263688 |
| 11 | MP0005551_abnormal_eye_electrophysiolog | 2.25658596 |
| 12 | MP0002653_abnormal_ependyma_morphology | 2.15431388 |
| 13 | MP0008995_early_reproductive_senescence | 2.00426034 |
| 14 | MP0008789_abnormal_olfactory_epithelium | 1.93868908 |
| 15 | MP0002138_abnormal_hepatobiliary_system | 1.90351215 |
| 16 | MP0003787_abnormal_imprinting | 1.89514109 |
| 17 | MP0000372_irregular_coat_pigmentation | 1.82800751 |
| 18 | MP0001968_abnormal_touch/_nociception | 1.77362620 |
| 19 | MP0004147_increased_porphyrin_level | 1.73465904 |
| 20 | MP0002160_abnormal_reproductive_system | 1.72547615 |
| 21 | MP0003283_abnormal_digestive_organ | 1.71391385 |
| 22 | MP0008872_abnormal_physiological_respon | 1.71210067 |
| 23 | MP0006276_abnormal_autonomic_nervous | 1.69399524 |
| 24 | MP0001905_abnormal_dopamine_level | 1.67633220 |
| 25 | MP0008058_abnormal_DNA_repair | 1.58458341 |
| 26 | MP0005389_reproductive_system_phenotype | 1.51678146 |
| 27 | MP0000678_abnormal_parathyroid_gland | 1.51456052 |
| 28 | MP0002163_abnormal_gland_morphology | 1.49703587 |
| 29 | MP0001188_hyperpigmentation | 1.46484877 |
| 30 | MP0001835_abnormal_antigen_presentation | 1.44770542 |
| 31 | MP0003195_calcinosis | 1.43008885 |
| 32 | MP0003786_premature_aging | 1.42760585 |
| 33 | MP0001485_abnormal_pinna_reflex | 1.41866552 |
| 34 | MP0002234_abnormal_pharynx_morphology | 1.41217863 |
| 35 | MP0001348_abnormal_lacrimal_gland | 1.40669494 |
| 36 | MP0009785_altered_susceptibility_to | 1.39865409 |
| 37 | MP0004885_abnormal_endolymph | 1.39746704 |
| 38 | MP0003646_muscle_fatigue | 1.38539290 |
| 39 | MP0009333_abnormal_splenocyte_physiolog | 1.36428879 |
| 40 | MP0001529_abnormal_vocalization | 1.34286138 |
| 41 | MP0005377_hearing/vestibular/ear_phenot | 1.32762510 |
| 42 | MP0003878_abnormal_ear_physiology | 1.32762510 |
| 43 | MP0001873_stomach_inflammation | 1.31230431 |
| 44 | MP0002736_abnormal_nociception_after | 1.29861240 |
| 45 | MP0005253_abnormal_eye_physiology | 1.28133261 |
| 46 | MP0003567_abnormal_fetal_cardiomyocyte | 1.27678653 |
| 47 | MP0005075_abnormal_melanosome_morpholog | 1.25263657 |
| 48 | MP0005670_abnormal_white_adipose | 1.19565276 |
| 49 | MP0002876_abnormal_thyroid_physiology | 1.18806033 |
| 50 | MP0001919_abnormal_reproductive_system | 1.16909805 |
| 51 | MP0005083_abnormal_biliary_tract | 1.15136167 |
| 52 | MP0005394_taste/olfaction_phenotype | 1.12931148 |
| 53 | MP0005499_abnormal_olfactory_system | 1.12931148 |
| 54 | MP0001800_abnormal_humoral_immune | 1.09047110 |
| 55 | MP0003806_abnormal_nucleotide_metabolis | 1.08068244 |
| 56 | MP0010386_abnormal_urinary_bladder | 1.04973275 |
| 57 | MP0004142_abnormal_muscle_tone | 1.04777446 |
| 58 | MP0005000_abnormal_immune_tolerance | 1.03988762 |
| 59 | MP0000631_abnormal_neuroendocrine_gland | 1.01538986 |
| 60 | MP0005379_endocrine/exocrine_gland_phen | 1.00298041 |
| 61 | MP0003122_maternal_imprinting | 0.98572034 |
| 62 | MP0001963_abnormal_hearing_physiology | 0.98058182 |
| 63 | MP0000026_abnormal_inner_ear | 0.97801114 |
| 64 | MP0003724_increased_susceptibility_to | 0.94521018 |
| 65 | MP0002272_abnormal_nervous_system | 0.93984902 |
| 66 | MP0006036_abnormal_mitochondrial_physio | 0.93426062 |
| 67 | MP0005636_abnormal_mineral_homeostasis | 0.91593018 |
| 68 | MP0000049_abnormal_middle_ear | 0.91425392 |
| 69 | MP0002396_abnormal_hematopoietic_system | 0.90591643 |
| 70 | MP0002723_abnormal_immune_serum | 0.89344174 |
| 71 | MP0003880_abnormal_central_pattern | 0.88059431 |
| 72 | MP0004133_heterotaxia | 0.87609290 |
| 73 | MP0008875_abnormal_xenobiotic_pharmacok | 0.87069239 |
| 74 | MP0001764_abnormal_homeostasis | 0.86684073 |
| 75 | MP0003866_abnormal_defecation | 0.85833676 |
| 76 | MP0002420_abnormal_adaptive_immunity | 0.84079915 |
| 77 | MP0001664_abnormal_digestion | 0.81134308 |
| 78 | MP0002638_abnormal_pupillary_reflex | 0.80795044 |
| 79 | MP0001819_abnormal_immune_cell | 0.80609979 |
| 80 | MP0004742_abnormal_vestibular_system | 0.80381350 |
| 81 | MP0003121_genomic_imprinting | 0.79088900 |
| 82 | MP0002095_abnormal_skin_pigmentation | 0.78697005 |
| 83 | MP0005332_abnormal_amino_acid | 0.78096760 |
| 84 | MP0002693_abnormal_pancreas_physiology | 0.77621403 |
| 85 | MP0001765_abnormal_ion_homeostasis | 0.75564781 |
| 86 | MP0000716_abnormal_immune_system | 0.74291048 |
| 87 | MP0005387_immune_system_phenotype | 0.73673578 |
| 88 | MP0001790_abnormal_immune_system | 0.73673578 |
| 89 | MP0003718_maternal_effect | 0.73197852 |
| 90 | MP0000689_abnormal_spleen_morphology | 0.70600659 |
| 91 | MP0004145_abnormal_muscle_electrophysio | 0.69924482 |
| 92 | MP0002398_abnormal_bone_marrow | 0.69687495 |
| 93 | MP0001984_abnormal_olfaction | 0.69509358 |
| 94 | MP0002452_abnormal_antigen_presenting | 0.68561385 |
| 95 | MP0003186_abnormal_redox_activity | 0.68353210 |
| 96 | MP0003123_paternal_imprinting | 0.66369260 |
| 97 | MP0000613_abnormal_salivary_gland | 0.65921606 |
| 98 | MP0001970_abnormal_pain_threshold | 0.65865998 |
| 99 | MP0001486_abnormal_startle_reflex | 0.65813360 |
| 100 | MP0002184_abnormal_innervation | 0.65349342 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Congenital stationary night blindness (HP:0007642) | 4.69708234 |
| 2 | Renal Fanconi syndrome (HP:0001994) | 4.39566297 |
| 3 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.37534297 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.00443155 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 3.84545023 |
| 6 | Abnormality of B cell number (HP:0010975) | 3.66144013 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.59166269 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.51668469 |
| 9 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.49244485 |
| 10 | Generalized aminoaciduria (HP:0002909) | 3.47030719 |
| 11 | Increased CSF lactate (HP:0002490) | 3.42410831 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.42274391 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.40158733 |
| 14 | Progressive macrocephaly (HP:0004481) | 3.24101821 |
| 15 | Asplenia (HP:0001746) | 3.22589084 |
| 16 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.18097013 |
| 17 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.14232181 |
| 18 | Reticulocytopenia (HP:0001896) | 3.13533301 |
| 19 | Acute encephalopathy (HP:0006846) | 3.13023060 |
| 20 | Abnormality of alanine metabolism (HP:0010916) | 3.12074697 |
| 21 | Hyperalaninemia (HP:0003348) | 3.12074697 |
| 22 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.12074697 |
| 23 | Hepatic necrosis (HP:0002605) | 3.11689354 |
| 24 | Abolished electroretinogram (ERG) (HP:0000550) | 3.03859470 |
| 25 | Decreased central vision (HP:0007663) | 2.96649777 |
| 26 | Pancreatic fibrosis (HP:0100732) | 2.93954607 |
| 27 | Increased intramyocellular lipid droplets (HP:0012240) | 2.89447108 |
| 28 | 3-Methylglutaconic aciduria (HP:0003535) | 2.86321856 |
| 29 | Pancreatic cysts (HP:0001737) | 2.86226958 |
| 30 | Abnormality of renal resorption (HP:0011038) | 2.84270584 |
| 31 | Increased IgM level (HP:0003496) | 2.81612965 |
| 32 | B lymphocytopenia (HP:0010976) | 2.79665555 |
| 33 | Hyperglycinemia (HP:0002154) | 2.74068424 |
| 34 | Hypoglycemic seizures (HP:0002173) | 2.73536148 |
| 35 | Cerebral edema (HP:0002181) | 2.72167131 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.71253286 |
| 37 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.69301768 |
| 38 | True hermaphroditism (HP:0010459) | 2.68188441 |
| 39 | Glycosuria (HP:0003076) | 2.67667601 |
| 40 | Abnormality of urine glucose concentration (HP:0011016) | 2.67667601 |
| 41 | Failure to thrive in infancy (HP:0001531) | 2.57585512 |
| 42 | Severe combined immunodeficiency (HP:0004430) | 2.52948335 |
| 43 | Increased muscle lipid content (HP:0009058) | 2.47990468 |
| 44 | Exertional dyspnea (HP:0002875) | 2.46266820 |
| 45 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.45471207 |
| 46 | Pendular nystagmus (HP:0012043) | 2.44099656 |
| 47 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.42816809 |
| 48 | Medial flaring of the eyebrow (HP:0010747) | 2.38025477 |
| 49 | Optic disc pallor (HP:0000543) | 2.37710532 |
| 50 | Molar tooth sign on MRI (HP:0002419) | 2.35735472 |
| 51 | Abnormality of midbrain morphology (HP:0002418) | 2.35735472 |
| 52 | Stomach cancer (HP:0012126) | 2.32568195 |
| 53 | Abnormal number of erythroid precursors (HP:0012131) | 2.31462580 |
| 54 | Aplastic anemia (HP:0001915) | 2.30205823 |
| 55 | Polydipsia (HP:0001959) | 2.29789992 |
| 56 | Abnormal drinking behavior (HP:0030082) | 2.29789992 |
| 57 | Lactic acidosis (HP:0003128) | 2.26697751 |
| 58 | IgG deficiency (HP:0004315) | 2.25541945 |
| 59 | Ketosis (HP:0001946) | 2.21081467 |
| 60 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.20105389 |
| 61 | Severe visual impairment (HP:0001141) | 2.19805410 |
| 62 | Reduced antithrombin III activity (HP:0001976) | 2.19762785 |
| 63 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.18471393 |
| 64 | Congenital primary aphakia (HP:0007707) | 2.17650784 |
| 65 | Methylmalonic acidemia (HP:0002912) | 2.16341685 |
| 66 | Increased serum lactate (HP:0002151) | 2.15682678 |
| 67 | Macrocytic anemia (HP:0001972) | 2.15097773 |
| 68 | Constricted visual fields (HP:0001133) | 2.13715209 |
| 69 | Gait imbalance (HP:0002141) | 2.13430317 |
| 70 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.10462656 |
| 71 | Colon cancer (HP:0003003) | 2.07378501 |
| 72 | Ketoacidosis (HP:0001993) | 2.06644118 |
| 73 | Nephrogenic diabetes insipidus (HP:0009806) | 1.98032701 |
| 74 | Autoimmune hemolytic anemia (HP:0001890) | 1.97612132 |
| 75 | Pallor (HP:0000980) | 1.97545450 |
| 76 | Combined immunodeficiency (HP:0005387) | 1.97292861 |
| 77 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.95052777 |
| 78 | Symptomatic seizures (HP:0011145) | 1.94589858 |
| 79 | Thyroiditis (HP:0100646) | 1.91986788 |
| 80 | Chronic sinusitis (HP:0011109) | 1.91558710 |
| 81 | Absent thumb (HP:0009777) | 1.91546128 |
| 82 | Lethargy (HP:0001254) | 1.88452140 |
| 83 | Type 2 muscle fiber atrophy (HP:0003554) | 1.87928448 |
| 84 | Abnormality of DNA repair (HP:0003254) | 1.87601893 |
| 85 | Abnormality of the costochondral junction (HP:0000919) | 1.87049374 |
| 86 | Hypoproteinemia (HP:0003075) | 1.86570472 |
| 87 | Nephronophthisis (HP:0000090) | 1.85612117 |
| 88 | Exercise intolerance (HP:0003546) | 1.85047182 |
| 89 | Abnormality of serum amino acid levels (HP:0003112) | 1.84844515 |
| 90 | Pancytopenia (HP:0001876) | 1.84733762 |
| 91 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.84678339 |
| 92 | Abnormality of the renal collecting system (HP:0004742) | 1.83612565 |
| 93 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.82957415 |
| 94 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.80994085 |
| 95 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.80994085 |
| 96 | Hyperphosphaturia (HP:0003109) | 1.79512034 |
| 97 | Tetany (HP:0001281) | 1.77209583 |
| 98 | Abnormality of eosinophils (HP:0001879) | 1.76660116 |
| 99 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.75309952 |
| 100 | Agammaglobulinemia (HP:0004432) | 1.74898665 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 4.17678855 |
| 2 | BCKDK | 3.52602147 |
| 3 | MAP4K2 | 3.28192643 |
| 4 | GRK1 | 3.07621663 |
| 5 | SCYL2 | 2.89086628 |
| 6 | TESK2 | 2.76555470 |
| 7 | PASK | 2.69823558 |
| 8 | VRK2 | 2.66163166 |
| 9 | ZAK | 2.60273356 |
| 10 | PBK | 2.47425475 |
| 11 | ADRBK2 | 2.35439748 |
| 12 | PINK1 | 2.27204119 |
| 13 | TXK | 2.25925653 |
| 14 | TAOK3 | 2.06563540 |
| 15 | PLK4 | 2.05713284 |
| 16 | TIE1 | 2.02197770 |
| 17 | MAP4K1 | 1.86244338 |
| 18 | CDK19 | 1.80832582 |
| 19 | FLT3 | 1.74587070 |
| 20 | KIT | 1.72566864 |
| 21 | FRK | 1.50630146 |
| 22 | GRK6 | 1.49254608 |
| 23 | VRK1 | 1.46130887 |
| 24 | BMPR1B | 1.43693282 |
| 25 | STK16 | 1.43229904 |
| 26 | PRKG2 | 1.31981084 |
| 27 | INSRR | 1.21242576 |
| 28 | NME1 | 1.18370093 |
| 29 | WNK3 | 1.12631565 |
| 30 | NUAK1 | 1.11087865 |
| 31 | TEC | 1.07221074 |
| 32 | BUB1 | 1.04416515 |
| 33 | MAP3K11 | 0.93306578 |
| 34 | DYRK2 | 0.92845278 |
| 35 | LIMK1 | 0.90732166 |
| 36 | TAF1 | 0.90223894 |
| 37 | WNK4 | 0.89783378 |
| 38 | MAP3K4 | 0.88535643 |
| 39 | IKBKE | 0.87182062 |
| 40 | MAP3K12 | 0.82407983 |
| 41 | ITK | 0.79111401 |
| 42 | SYK | 0.74870460 |
| 43 | PRKCQ | 0.72603781 |
| 44 | ADRBK1 | 0.68743878 |
| 45 | TLK1 | 0.66713622 |
| 46 | DAPK2 | 0.66703776 |
| 47 | TNIK | 0.65564184 |
| 48 | EIF2AK3 | 0.62232257 |
| 49 | CSF1R | 0.61250916 |
| 50 | RPS6KB2 | 0.61150714 |
| 51 | LYN | 0.59892304 |
| 52 | ZAP70 | 0.57041550 |
| 53 | DAPK3 | 0.56717800 |
| 54 | NME2 | 0.56263415 |
| 55 | CSNK1G3 | 0.56067800 |
| 56 | TGFBR1 | 0.55878350 |
| 57 | RPS6KA5 | 0.55056969 |
| 58 | ACVR1B | 0.53460625 |
| 59 | PLK2 | 0.53458502 |
| 60 | OBSCN | 0.52507907 |
| 61 | PIM1 | 0.52191872 |
| 62 | STK39 | 0.50293351 |
| 63 | IRAK4 | 0.49589043 |
| 64 | IKBKB | 0.49240212 |
| 65 | PLK3 | 0.48385471 |
| 66 | AURKA | 0.46753107 |
| 67 | SRPK1 | 0.46675118 |
| 68 | RPS6KA4 | 0.45614141 |
| 69 | PRKCH | 0.45316953 |
| 70 | MYLK | 0.44827340 |
| 71 | PRKACA | 0.44274724 |
| 72 | GRK5 | 0.44015015 |
| 73 | LCK | 0.43281530 |
| 74 | BLK | 0.43242767 |
| 75 | CSNK1G2 | 0.42878015 |
| 76 | ARAF | 0.42455130 |
| 77 | FES | 0.42435304 |
| 78 | CDK8 | 0.42409717 |
| 79 | PRKCE | 0.42377962 |
| 80 | EPHB2 | 0.42321238 |
| 81 | PLK1 | 0.41867349 |
| 82 | CSNK1G1 | 0.40925691 |
| 83 | MST4 | 0.40588312 |
| 84 | MAP2K6 | 0.40494593 |
| 85 | MAPK13 | 0.39612639 |
| 86 | STK4 | 0.38862000 |
| 87 | PIK3CG | 0.38201503 |
| 88 | PRKCA | 0.36480248 |
| 89 | MATK | 0.36185255 |
| 90 | CSNK2A2 | 0.34479410 |
| 91 | OXSR1 | 0.33857671 |
| 92 | MAPKAPK5 | 0.33708594 |
| 93 | PHKG1 | 0.32552894 |
| 94 | PHKG2 | 0.32552894 |
| 95 | CAMKK1 | 0.31621777 |
| 96 | AURKB | 0.31614267 |
| 97 | CSNK2A1 | 0.30823977 |
| 98 | NTRK3 | 0.30571092 |
| 99 | RPS6KA6 | 0.30425776 |
| 100 | MKNK1 | 0.29617501 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.48166542 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.07597665 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.52646971 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.21803799 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.17486262 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.77523086 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.18947582 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.10901598 |
| 9 | RNA degradation_Homo sapiens_hsa03018 | 1.99654930 |
| 10 | Protein export_Homo sapiens_hsa03060 | 1.98019433 |
| 11 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.96132627 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.86286200 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 1.77190761 |
| 14 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.69454245 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.69275315 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.68397256 |
| 17 | Phototransduction_Homo sapiens_hsa04744 | 1.66560300 |
| 18 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.59335208 |
| 19 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.52892569 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.52839325 |
| 21 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.51705245 |
| 22 | Asthma_Homo sapiens_hsa05310 | 1.51610206 |
| 23 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.50573323 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.48484652 |
| 25 | DNA replication_Homo sapiens_hsa03030 | 1.48369370 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.42806057 |
| 27 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.41282084 |
| 28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.38702825 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.37285533 |
| 30 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.36096088 |
| 31 | Base excision repair_Homo sapiens_hsa03410 | 1.32418385 |
| 32 | Homologous recombination_Homo sapiens_hsa03440 | 1.30771395 |
| 33 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.29843534 |
| 34 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26336360 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.23595857 |
| 36 | Mismatch repair_Homo sapiens_hsa03430 | 1.21109923 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.20860698 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.14600985 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.12838476 |
| 40 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.04981348 |
| 41 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.03721384 |
| 42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.03145659 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 0.99728283 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 0.98723487 |
| 45 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.98120601 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.97298935 |
| 47 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.94609357 |
| 48 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.92195901 |
| 49 | RNA transport_Homo sapiens_hsa03013 | 0.91553599 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 0.91472643 |
| 51 | Retinol metabolism_Homo sapiens_hsa00830 | 0.89534686 |
| 52 | Taste transduction_Homo sapiens_hsa04742 | 0.84697801 |
| 53 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.83749027 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.83269388 |
| 55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.83066979 |
| 56 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.78101618 |
| 57 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.77626493 |
| 58 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.75814944 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.75093692 |
| 60 | Basal transcription factors_Homo sapiens_hsa03022 | 0.74517368 |
| 61 | Nicotine addiction_Homo sapiens_hsa05033 | 0.72320675 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70960164 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.69669065 |
| 64 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67660107 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.67394136 |
| 66 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.67138639 |
| 67 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64787190 |
| 68 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.63915463 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.63619733 |
| 70 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.63365150 |
| 71 | Spliceosome_Homo sapiens_hsa03040 | 0.61329358 |
| 72 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59753456 |
| 73 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.58102907 |
| 74 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57455138 |
| 75 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.56993889 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.53613071 |
| 77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.52007975 |
| 78 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50850056 |
| 79 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49545689 |
| 80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.46589542 |
| 81 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43976897 |
| 82 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.43884756 |
| 83 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.39757633 |
| 84 | Morphine addiction_Homo sapiens_hsa05032 | 0.37869455 |
| 85 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.37703902 |
| 86 | Salivary secretion_Homo sapiens_hsa04970 | 0.37464625 |
| 87 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.37177743 |
| 88 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.34142110 |
| 89 | Viral myocarditis_Homo sapiens_hsa05416 | 0.33908051 |
| 90 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.32129064 |
| 91 | Circadian entrainment_Homo sapiens_hsa04713 | 0.30424466 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.29699422 |
| 93 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.27851291 |
| 94 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.26005256 |
| 95 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.25264165 |
| 96 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.24821864 |
| 97 | ABC transporters_Homo sapiens_hsa02010 | 0.24023637 |
| 98 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.23052029 |
| 99 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.21153194 |
| 100 | Sulfur relay system_Homo sapiens_hsa04122 | 0.20814339 |

