RPSAP15

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)8.12519489
2DNA deamination (GO:0045006)6.11758307
3regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450915.35288496
4mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.24060895
5sequestering of actin monomers (GO:0042989)5.20850303
6ATP synthesis coupled proton transport (GO:0015986)5.00521903
7energy coupled proton transport, down electrochemical gradient (GO:0015985)5.00521903
8cytidine metabolic process (GO:0046087)4.84202186
9cytidine catabolic process (GO:0006216)4.84202186
10cytidine deamination (GO:0009972)4.84202186
11viral transcription (GO:0019083)4.83323336
12translational termination (GO:0006415)4.69059502
13translational elongation (GO:0006414)4.29789224
14pyrimidine ribonucleoside catabolic process (GO:0046133)4.21874479
15RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.17896236
16tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.17896236
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.13974973
18cotranslational protein targeting to membrane (GO:0006613)4.09182992
19mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.08913793
20NADH dehydrogenase complex assembly (GO:0010257)4.06081468
21mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.06081468
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.06081468
23protein targeting to ER (GO:0045047)4.04301974
24protein neddylation (GO:0045116)4.03189106
25protein complex biogenesis (GO:0070271)4.01191693
26nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.93005876
27respiratory electron transport chain (GO:0022904)3.84911083
28behavioral response to nicotine (GO:0035095)3.84715849
29electron transport chain (GO:0022900)3.82487336
30exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.82269442
31establishment of protein localization to endoplasmic reticulum (GO:0072599)3.81711291
32Arp2/3 complex-mediated actin nucleation (GO:0034314)3.81578129
33ribosomal large subunit biogenesis (GO:0042273)3.78378195
34protein localization to endoplasmic reticulum (GO:0070972)3.77585956
35pseudouridine synthesis (GO:0001522)3.74610968
36ribosomal small subunit biogenesis (GO:0042274)3.66281241
37cellular ketone body metabolic process (GO:0046950)3.59437935
38ncRNA 3-end processing (GO:0043628)3.58934689
39actin nucleation (GO:0045010)3.57780638
40cellular protein complex disassembly (GO:0043624)3.51416354
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.49062913
42viral life cycle (GO:0019058)3.47974089
43mitochondrial respiratory chain complex assembly (GO:0033108)3.46060047
44translational initiation (GO:0006413)3.42081800
45maturation of SSU-rRNA (GO:0030490)3.40186045
46chaperone-mediated protein transport (GO:0072321)3.38099208
47nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.33874536
48purine nucleotide salvage (GO:0032261)3.26991440
49ketone body metabolic process (GO:1902224)3.24228402
50translation (GO:0006412)3.19896738
51RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.11147119
52cellular component biogenesis (GO:0044085)2.95975651
53regulation of appetite (GO:0032098)2.90844562
54negative regulation of response to food (GO:0032096)2.88206052
55negative regulation of appetite (GO:0032099)2.88206052
56water-soluble vitamin biosynthetic process (GO:0042364)2.84626187
57aldehyde catabolic process (GO:0046185)2.84250203
58ribonucleoprotein complex biogenesis (GO:0022613)2.83874108
59deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.82891044
60protein complex disassembly (GO:0043241)2.82037321
61drinking behavior (GO:0042756)2.80445733
62hydrogen ion transmembrane transport (GO:1902600)2.79536422
63piRNA metabolic process (GO:0034587)2.77157673
64proton transport (GO:0015992)2.75485967
65proteasome assembly (GO:0043248)2.74745441
66hydrogen transport (GO:0006818)2.73969363
67macromolecular complex disassembly (GO:0032984)2.73685834
68adenosine metabolic process (GO:0046085)2.73482866
69protein-cofactor linkage (GO:0018065)2.72739920
70nuclear-transcribed mRNA catabolic process (GO:0000956)2.71112652
71S-adenosylmethionine metabolic process (GO:0046500)2.70702075
72purine deoxyribonucleotide catabolic process (GO:0009155)2.67238434
73ATP biosynthetic process (GO:0006754)2.65968993
74metallo-sulfur cluster assembly (GO:0031163)2.63823434
75iron-sulfur cluster assembly (GO:0016226)2.63823434
76protein polyglutamylation (GO:0018095)2.61745497
77nonmotile primary cilium assembly (GO:0035058)2.61679045
78negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.59455193
79positive thymic T cell selection (GO:0045059)2.59224557
80negative regulation of oxidoreductase activity (GO:0051354)2.59169195
81platelet dense granule organization (GO:0060155)2.59023581
82cytochrome complex assembly (GO:0017004)2.57051170
83mannosylation (GO:0097502)2.55520921
84protein deneddylation (GO:0000338)2.54536239
85mRNA catabolic process (GO:0006402)2.53652035
86respiratory chain complex IV assembly (GO:0008535)2.53413295
87protein targeting to membrane (GO:0006612)2.53217755
88deoxyribonucleotide catabolic process (GO:0009264)2.50651901
89purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.49731362
90positive T cell selection (GO:0043368)2.48035176
91DNA demethylation (GO:0080111)2.47872646
92DNA dealkylation (GO:0035510)2.47769709
93purine nucleoside triphosphate biosynthetic process (GO:0009145)2.47383905
94rRNA processing (GO:0006364)2.46254848
95negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.46248449
96response to interferon-beta (GO:0035456)2.45865788
97rRNA metabolic process (GO:0016072)2.45372154
98base-excision repair, AP site formation (GO:0006285)2.44004934
99deoxyribose phosphate catabolic process (GO:0046386)2.43834251
100protein K6-linked ubiquitination (GO:0085020)2.39493818

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse6.40391487
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.39608130
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.34182054
4VDR_22108803_ChIP-Seq_LS180_Human3.33907508
5HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.22168927
6ELF1_17652178_ChIP-ChIP_JURKAT_Human3.12693383
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.77141667
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.65111911
9IGF1R_20145208_ChIP-Seq_DFB_Human2.60857356
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.59178298
11EZH2_22144423_ChIP-Seq_EOC_Human2.44026009
12NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.41903081
13ZNF274_21170338_ChIP-Seq_K562_Hela2.38351980
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.33186027
15NOTCH1_21737748_ChIP-Seq_TLL_Human2.19141032
16ETS1_20019798_ChIP-Seq_JURKAT_Human2.14426405
17FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.06508279
18MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.02705640
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.94400484
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.93986618
21VDR_23849224_ChIP-Seq_CD4+_Human1.93017000
22EWS_26573619_Chip-Seq_HEK293_Human1.90743373
23IRF8_22096565_ChIP-ChIP_GC-B_Human1.73281282
24RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.71336904
25FOXP3_21729870_ChIP-Seq_TREG_Human1.71285674
26CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69102837
27MYC_18940864_ChIP-ChIP_HL60_Human1.61161912
28ELK1_19687146_ChIP-ChIP_HELA_Human1.59835312
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.58283292
30IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.58025602
31SRF_21415370_ChIP-Seq_HL-1_Mouse1.57410241
32EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.53734444
33PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.53589232
34GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51585336
35FLI1_27457419_Chip-Seq_LIVER_Mouse1.50231842
36MYC_18555785_ChIP-Seq_MESCs_Mouse1.48861833
37FOXA1_27270436_Chip-Seq_PROSTATE_Human1.47906897
38FOXA1_25329375_ChIP-Seq_VCAP_Human1.47906897
39AR_20517297_ChIP-Seq_VCAP_Human1.47860609
40CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.43908732
41CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40309689
42PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.38275536
43MYC_18358816_ChIP-ChIP_MESCs_Mouse1.36292760
44NCOR_22424771_ChIP-Seq_293T_Human1.35764917
45POU5F1_16153702_ChIP-ChIP_HESCs_Human1.33241846
46CREB1_15753290_ChIP-ChIP_HEK293T_Human1.31949795
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31835850
48AUTS2_25519132_ChIP-Seq_293T-REX_Human1.31165375
49TP53_22573176_ChIP-Seq_HFKS_Human1.31043945
50MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30227398
51YY1_22570637_ChIP-Seq_MALME-3M_Human1.30110414
52ETV2_25802403_ChIP-Seq_MESCs_Mouse1.28000580
53FUS_26573619_Chip-Seq_HEK293_Human1.26579320
54RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.25450199
55FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.25297842
56GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.22935039
57PCGF2_27294783_Chip-Seq_ESCs_Mouse1.22705557
58RNF2_27304074_Chip-Seq_NSC_Mouse1.21722595
59NANOG_20526341_ChIP-Seq_ESCs_Human1.20109656
60ERG_20517297_ChIP-Seq_VCAP_Human1.17685799
61ER_23166858_ChIP-Seq_MCF-7_Human1.17252881
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.16573774
63GATA3_21878914_ChIP-Seq_MCF-7_Human1.16289473
64P300_19829295_ChIP-Seq_ESCs_Human1.16132330
65STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.15805658
66SOX2_19829295_ChIP-Seq_ESCs_Human1.14575534
67NANOG_19829295_ChIP-Seq_ESCs_Human1.14575534
68GBX2_23144817_ChIP-Seq_PC3_Human1.13726290
69CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.11371371
70LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.11354631
71BP1_19119308_ChIP-ChIP_Hs578T_Human1.09853514
72TTF2_22483619_ChIP-Seq_HELA_Human1.07361182
73CBP_20019798_ChIP-Seq_JUKART_Human1.07170860
74IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.07170860
75IRF8_21731497_ChIP-ChIP_J774_Mouse1.04201039
76CBX2_27304074_Chip-Seq_ESCs_Mouse1.03136067
77TAF2_19829295_ChIP-Seq_ESCs_Human1.01821833
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01574165
79PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.00854077
80MYC_19829295_ChIP-Seq_ESCs_Human1.00436380
81HTT_18923047_ChIP-ChIP_STHdh_Human1.00422469
82MYB_26560356_Chip-Seq_TH2_Human0.99203859
83KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99189029
84ZFP57_27257070_Chip-Seq_ESCs_Mouse0.99112378
85GATA3_26560356_Chip-Seq_TH2_Human0.96999296
86CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.95519909
87EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.95012590
88FOXA1_21572438_ChIP-Seq_LNCaP_Human0.93629676
89TAF15_26573619_Chip-Seq_HEK293_Human0.91843579
90SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.91735363
91MYC_19030024_ChIP-ChIP_MESCs_Mouse0.91586049
92EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91328061
93FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.89886721
94BCAT_22108803_ChIP-Seq_LS180_Human0.89627069
95TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88824133
96PHF8_20622853_ChIP-Seq_HELA_Human0.88064441
97P53_21459846_ChIP-Seq_SAOS-2_Human0.88019747
98GATA3_21867929_ChIP-Seq_TH1_Mouse0.87829246
99EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.86874138
100HOXB4_20404135_ChIP-ChIP_EML_Mouse0.86351481

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.10655103
2MP0005084_abnormal_gallbladder_morpholo3.15080025
3MP0008877_abnormal_DNA_methylation2.68877134
4MP0006072_abnormal_retinal_apoptosis2.64738811
5MP0005645_abnormal_hypothalamus_physiol2.52625976
6MP0005671_abnormal_response_to2.49686927
7MP0002837_dystrophic_cardiac_calcinosis2.49150009
8MP0005646_abnormal_pituitary_gland2.42318403
9MP0006292_abnormal_olfactory_placode2.40108090
10MP0002102_abnormal_ear_morphology2.31263688
11MP0005551_abnormal_eye_electrophysiolog2.25658596
12MP0002653_abnormal_ependyma_morphology2.15431388
13MP0008995_early_reproductive_senescence2.00426034
14MP0008789_abnormal_olfactory_epithelium1.93868908
15MP0002138_abnormal_hepatobiliary_system1.90351215
16MP0003787_abnormal_imprinting1.89514109
17MP0000372_irregular_coat_pigmentation1.82800751
18MP0001968_abnormal_touch/_nociception1.77362620
19MP0004147_increased_porphyrin_level1.73465904
20MP0002160_abnormal_reproductive_system1.72547615
21MP0003283_abnormal_digestive_organ1.71391385
22MP0008872_abnormal_physiological_respon1.71210067
23MP0006276_abnormal_autonomic_nervous1.69399524
24MP0001905_abnormal_dopamine_level1.67633220
25MP0008058_abnormal_DNA_repair1.58458341
26MP0005389_reproductive_system_phenotype1.51678146
27MP0000678_abnormal_parathyroid_gland1.51456052
28MP0002163_abnormal_gland_morphology1.49703587
29MP0001188_hyperpigmentation1.46484877
30MP0001835_abnormal_antigen_presentation1.44770542
31MP0003195_calcinosis1.43008885
32MP0003786_premature_aging1.42760585
33MP0001485_abnormal_pinna_reflex1.41866552
34MP0002234_abnormal_pharynx_morphology1.41217863
35MP0001348_abnormal_lacrimal_gland1.40669494
36MP0009785_altered_susceptibility_to1.39865409
37MP0004885_abnormal_endolymph1.39746704
38MP0003646_muscle_fatigue1.38539290
39MP0009333_abnormal_splenocyte_physiolog1.36428879
40MP0001529_abnormal_vocalization1.34286138
41MP0005377_hearing/vestibular/ear_phenot1.32762510
42MP0003878_abnormal_ear_physiology1.32762510
43MP0001873_stomach_inflammation1.31230431
44MP0002736_abnormal_nociception_after1.29861240
45MP0005253_abnormal_eye_physiology1.28133261
46MP0003567_abnormal_fetal_cardiomyocyte1.27678653
47MP0005075_abnormal_melanosome_morpholog1.25263657
48MP0005670_abnormal_white_adipose1.19565276
49MP0002876_abnormal_thyroid_physiology1.18806033
50MP0001919_abnormal_reproductive_system1.16909805
51MP0005083_abnormal_biliary_tract1.15136167
52MP0005394_taste/olfaction_phenotype1.12931148
53MP0005499_abnormal_olfactory_system1.12931148
54MP0001800_abnormal_humoral_immune1.09047110
55MP0003806_abnormal_nucleotide_metabolis1.08068244
56MP0010386_abnormal_urinary_bladder1.04973275
57MP0004142_abnormal_muscle_tone1.04777446
58MP0005000_abnormal_immune_tolerance1.03988762
59MP0000631_abnormal_neuroendocrine_gland1.01538986
60MP0005379_endocrine/exocrine_gland_phen1.00298041
61MP0003122_maternal_imprinting0.98572034
62MP0001963_abnormal_hearing_physiology0.98058182
63MP0000026_abnormal_inner_ear0.97801114
64MP0003724_increased_susceptibility_to0.94521018
65MP0002272_abnormal_nervous_system0.93984902
66MP0006036_abnormal_mitochondrial_physio0.93426062
67MP0005636_abnormal_mineral_homeostasis0.91593018
68MP0000049_abnormal_middle_ear0.91425392
69MP0002396_abnormal_hematopoietic_system0.90591643
70MP0002723_abnormal_immune_serum0.89344174
71MP0003880_abnormal_central_pattern0.88059431
72MP0004133_heterotaxia0.87609290
73MP0008875_abnormal_xenobiotic_pharmacok0.87069239
74MP0001764_abnormal_homeostasis0.86684073
75MP0003866_abnormal_defecation0.85833676
76MP0002420_abnormal_adaptive_immunity0.84079915
77MP0001664_abnormal_digestion0.81134308
78MP0002638_abnormal_pupillary_reflex0.80795044
79MP0001819_abnormal_immune_cell0.80609979
80MP0004742_abnormal_vestibular_system0.80381350
81MP0003121_genomic_imprinting0.79088900
82MP0002095_abnormal_skin_pigmentation0.78697005
83MP0005332_abnormal_amino_acid0.78096760
84MP0002693_abnormal_pancreas_physiology0.77621403
85MP0001765_abnormal_ion_homeostasis0.75564781
86MP0000716_abnormal_immune_system0.74291048
87MP0005387_immune_system_phenotype0.73673578
88MP0001790_abnormal_immune_system0.73673578
89MP0003718_maternal_effect0.73197852
90MP0000689_abnormal_spleen_morphology0.70600659
91MP0004145_abnormal_muscle_electrophysio0.69924482
92MP0002398_abnormal_bone_marrow0.69687495
93MP0001984_abnormal_olfaction0.69509358
94MP0002452_abnormal_antigen_presenting0.68561385
95MP0003186_abnormal_redox_activity0.68353210
96MP0003123_paternal_imprinting0.66369260
97MP0000613_abnormal_salivary_gland0.65921606
98MP0001970_abnormal_pain_threshold0.65865998
99MP0001486_abnormal_startle_reflex0.65813360
100MP0002184_abnormal_innervation0.65349342

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)4.69708234
2Renal Fanconi syndrome (HP:0001994)4.39566297
3Absent rod-and cone-mediated responses on ERG (HP:0007688)4.37534297
4Mitochondrial inheritance (HP:0001427)4.00443155
5Acute necrotizing encephalopathy (HP:0006965)3.84545023
6Abnormality of B cell number (HP:0010975)3.66144013
7Increased hepatocellular lipid droplets (HP:0006565)3.59166269
8Abnormal mitochondria in muscle tissue (HP:0008316)3.51668469
9Abnormal rod and cone electroretinograms (HP:0008323)3.49244485
10Generalized aminoaciduria (HP:0002909)3.47030719
11Increased CSF lactate (HP:0002490)3.42410831
12Hepatocellular necrosis (HP:0001404)3.42274391
13Lipid accumulation in hepatocytes (HP:0006561)3.40158733
14Progressive macrocephaly (HP:0004481)3.24101821
15Asplenia (HP:0001746)3.22589084
16Aplasia/Hypoplasia of the spleen (HP:0010451)3.18097013
17Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.14232181
18Reticulocytopenia (HP:0001896)3.13533301
19Acute encephalopathy (HP:0006846)3.13023060
20Abnormality of alanine metabolism (HP:0010916)3.12074697
21Hyperalaninemia (HP:0003348)3.12074697
22Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.12074697
23Hepatic necrosis (HP:0002605)3.11689354
24Abolished electroretinogram (ERG) (HP:0000550)3.03859470
25Decreased central vision (HP:0007663)2.96649777
26Pancreatic fibrosis (HP:0100732)2.93954607
27Increased intramyocellular lipid droplets (HP:0012240)2.89447108
283-Methylglutaconic aciduria (HP:0003535)2.86321856
29Pancreatic cysts (HP:0001737)2.86226958
30Abnormality of renal resorption (HP:0011038)2.84270584
31Increased IgM level (HP:0003496)2.81612965
32B lymphocytopenia (HP:0010976)2.79665555
33Hyperglycinemia (HP:0002154)2.74068424
34Hypoglycemic seizures (HP:0002173)2.73536148
35Cerebral edema (HP:0002181)2.72167131
36Attenuation of retinal blood vessels (HP:0007843)2.71253286
37Elevated erythrocyte sedimentation rate (HP:0003565)2.69301768
38True hermaphroditism (HP:0010459)2.68188441
39Glycosuria (HP:0003076)2.67667601
40Abnormality of urine glucose concentration (HP:0011016)2.67667601
41Failure to thrive in infancy (HP:0001531)2.57585512
42Severe combined immunodeficiency (HP:0004430)2.52948335
43Increased muscle lipid content (HP:0009058)2.47990468
44Exertional dyspnea (HP:0002875)2.46266820
45Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.45471207
46Pendular nystagmus (HP:0012043)2.44099656
47Abnormality of cells of the erythroid lineage (HP:0012130)2.42816809
48Medial flaring of the eyebrow (HP:0010747)2.38025477
49Optic disc pallor (HP:0000543)2.37710532
50Molar tooth sign on MRI (HP:0002419)2.35735472
51Abnormality of midbrain morphology (HP:0002418)2.35735472
52Stomach cancer (HP:0012126)2.32568195
53Abnormal number of erythroid precursors (HP:0012131)2.31462580
54Aplastic anemia (HP:0001915)2.30205823
55Polydipsia (HP:0001959)2.29789992
56Abnormal drinking behavior (HP:0030082)2.29789992
57Lactic acidosis (HP:0003128)2.26697751
58IgG deficiency (HP:0004315)2.25541945
59Ketosis (HP:0001946)2.21081467
60Abnormality of the phalanges of the 2nd finger (HP:0009541)2.20105389
61Severe visual impairment (HP:0001141)2.19805410
62Reduced antithrombin III activity (HP:0001976)2.19762785
63Decreased electroretinogram (ERG) amplitude (HP:0000654)2.18471393
64Congenital primary aphakia (HP:0007707)2.17650784
65Methylmalonic acidemia (HP:0002912)2.16341685
66Increased serum lactate (HP:0002151)2.15682678
67Macrocytic anemia (HP:0001972)2.15097773
68Constricted visual fields (HP:0001133)2.13715209
69Gait imbalance (HP:0002141)2.13430317
70Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.10462656
71Colon cancer (HP:0003003)2.07378501
72Ketoacidosis (HP:0001993)2.06644118
73Nephrogenic diabetes insipidus (HP:0009806)1.98032701
74Autoimmune hemolytic anemia (HP:0001890)1.97612132
75Pallor (HP:0000980)1.97545450
76Combined immunodeficiency (HP:0005387)1.97292861
77Abnormality of the phalanges of the 5th finger (HP:0004213)1.95052777
78Symptomatic seizures (HP:0011145)1.94589858
79Thyroiditis (HP:0100646)1.91986788
80Chronic sinusitis (HP:0011109)1.91558710
81Absent thumb (HP:0009777)1.91546128
82Lethargy (HP:0001254)1.88452140
83Type 2 muscle fiber atrophy (HP:0003554)1.87928448
84Abnormality of DNA repair (HP:0003254)1.87601893
85Abnormality of the costochondral junction (HP:0000919)1.87049374
86Hypoproteinemia (HP:0003075)1.86570472
87Nephronophthisis (HP:0000090)1.85612117
88Exercise intolerance (HP:0003546)1.85047182
89Abnormality of serum amino acid levels (HP:0003112)1.84844515
90Pancytopenia (HP:0001876)1.84733762
91Aplasia/Hypoplasia of the sacrum (HP:0008517)1.84678339
92Abnormality of the renal collecting system (HP:0004742)1.83612565
93Aplasia/Hypoplasia of the uvula (HP:0010293)1.82957415
94Decreased activity of mitochondrial respiratory chain (HP:0008972)1.80994085
95Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.80994085
96Hyperphosphaturia (HP:0003109)1.79512034
97Tetany (HP:0001281)1.77209583
98Abnormality of eosinophils (HP:0001879)1.76660116
99Aplasia/hypoplasia of the uterus (HP:0008684)1.75309952
100Agammaglobulinemia (HP:0004432)1.74898665

Predicted kinase interactions (KEA)

RankGene SetZ-score
1KDR4.17678855
2BCKDK3.52602147
3MAP4K23.28192643
4GRK13.07621663
5SCYL22.89086628
6TESK22.76555470
7PASK2.69823558
8VRK22.66163166
9ZAK2.60273356
10PBK2.47425475
11ADRBK22.35439748
12PINK12.27204119
13TXK2.25925653
14TAOK32.06563540
15PLK42.05713284
16TIE12.02197770
17MAP4K11.86244338
18CDK191.80832582
19FLT31.74587070
20KIT1.72566864
21FRK1.50630146
22GRK61.49254608
23VRK11.46130887
24BMPR1B1.43693282
25STK161.43229904
26PRKG21.31981084
27INSRR1.21242576
28NME11.18370093
29WNK31.12631565
30NUAK11.11087865
31TEC1.07221074
32BUB11.04416515
33MAP3K110.93306578
34DYRK20.92845278
35LIMK10.90732166
36TAF10.90223894
37WNK40.89783378
38MAP3K40.88535643
39IKBKE0.87182062
40MAP3K120.82407983
41ITK0.79111401
42SYK0.74870460
43PRKCQ0.72603781
44ADRBK10.68743878
45TLK10.66713622
46DAPK20.66703776
47TNIK0.65564184
48EIF2AK30.62232257
49CSF1R0.61250916
50RPS6KB20.61150714
51LYN0.59892304
52ZAP700.57041550
53DAPK30.56717800
54NME20.56263415
55CSNK1G30.56067800
56TGFBR10.55878350
57RPS6KA50.55056969
58ACVR1B0.53460625
59PLK20.53458502
60OBSCN0.52507907
61PIM10.52191872
62STK390.50293351
63IRAK40.49589043
64IKBKB0.49240212
65PLK30.48385471
66AURKA0.46753107
67SRPK10.46675118
68RPS6KA40.45614141
69PRKCH0.45316953
70MYLK0.44827340
71PRKACA0.44274724
72GRK50.44015015
73LCK0.43281530
74BLK0.43242767
75CSNK1G20.42878015
76ARAF0.42455130
77FES0.42435304
78CDK80.42409717
79PRKCE0.42377962
80EPHB20.42321238
81PLK10.41867349
82CSNK1G10.40925691
83MST40.40588312
84MAP2K60.40494593
85MAPK130.39612639
86STK40.38862000
87PIK3CG0.38201503
88PRKCA0.36480248
89MATK0.36185255
90CSNK2A20.34479410
91OXSR10.33857671
92MAPKAPK50.33708594
93PHKG10.32552894
94PHKG20.32552894
95CAMKK10.31621777
96AURKB0.31614267
97CSNK2A10.30823977
98NTRK30.30571092
99RPS6KA60.30425776
100MKNK10.29617501

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.48166542
2Oxidative phosphorylation_Homo sapiens_hsa001904.07597665
3Primary immunodeficiency_Homo sapiens_hsa053403.52646971
4Parkinsons disease_Homo sapiens_hsa050123.21803799
5Proteasome_Homo sapiens_hsa030503.17486262
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.77523086
7Alzheimers disease_Homo sapiens_hsa050102.18947582
8Huntingtons disease_Homo sapiens_hsa050162.10901598
9RNA degradation_Homo sapiens_hsa030181.99654930
10Protein export_Homo sapiens_hsa030601.98019433
11Maturity onset diabetes of the young_Homo sapiens_hsa049501.96132627
12Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.86286200
13RNA polymerase_Homo sapiens_hsa030201.77190761
14Cardiac muscle contraction_Homo sapiens_hsa042601.69454245
15Allograft rejection_Homo sapiens_hsa053301.69275315
16Autoimmune thyroid disease_Homo sapiens_hsa053201.68397256
17Phototransduction_Homo sapiens_hsa047441.66560300
18Type I diabetes mellitus_Homo sapiens_hsa049401.59335208
19Graft-versus-host disease_Homo sapiens_hsa053321.52892569
20One carbon pool by folate_Homo sapiens_hsa006701.52839325
21Intestinal immune network for IgA production_Homo sapiens_hsa046721.51705245
22Asthma_Homo sapiens_hsa053101.51610206
23Fanconi anemia pathway_Homo sapiens_hsa034601.50573323
24Butanoate metabolism_Homo sapiens_hsa006501.48484652
25DNA replication_Homo sapiens_hsa030301.48369370
26Antigen processing and presentation_Homo sapiens_hsa046121.42806057
27Collecting duct acid secretion_Homo sapiens_hsa049661.41282084
28Hematopoietic cell lineage_Homo sapiens_hsa046401.38702825
29Linoleic acid metabolism_Homo sapiens_hsa005911.37285533
30Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.36096088
31Base excision repair_Homo sapiens_hsa034101.32418385
32Homologous recombination_Homo sapiens_hsa034401.30771395
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.29843534
34Pyrimidine metabolism_Homo sapiens_hsa002401.26336360
35Propanoate metabolism_Homo sapiens_hsa006401.23595857
36Mismatch repair_Homo sapiens_hsa034301.21109923
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.20860698
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.14600985
39alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.12838476
40Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04981348
41Selenocompound metabolism_Homo sapiens_hsa004501.03721384
42Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.03145659
43Olfactory transduction_Homo sapiens_hsa047400.99728283
44Peroxisome_Homo sapiens_hsa041460.98723487
45Nucleotide excision repair_Homo sapiens_hsa034200.98120601
46Rheumatoid arthritis_Homo sapiens_hsa053230.97298935
47Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.94609357
48Vitamin B6 metabolism_Homo sapiens_hsa007500.92195901
49RNA transport_Homo sapiens_hsa030130.91553599
50Purine metabolism_Homo sapiens_hsa002300.91472643
51Retinol metabolism_Homo sapiens_hsa008300.89534686
52Taste transduction_Homo sapiens_hsa047420.84697801
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.83749027
54Nitrogen metabolism_Homo sapiens_hsa009100.83269388
55Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.83066979
56Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.78101618
57Steroid hormone biosynthesis_Homo sapiens_hsa001400.77626493
58Arachidonic acid metabolism_Homo sapiens_hsa005900.75814944
59Chemical carcinogenesis_Homo sapiens_hsa052040.75093692
60Basal transcription factors_Homo sapiens_hsa030220.74517368
61Nicotine addiction_Homo sapiens_hsa050330.72320675
62Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70960164
63Metabolic pathways_Homo sapiens_hsa011000.69669065
64Sulfur metabolism_Homo sapiens_hsa009200.67660107
65Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67394136
66Non-homologous end-joining_Homo sapiens_hsa034500.67138639
67Ether lipid metabolism_Homo sapiens_hsa005650.64787190
68Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.63915463
69Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63619733
70Primary bile acid biosynthesis_Homo sapiens_hsa001200.63365150
71Spliceosome_Homo sapiens_hsa030400.61329358
72Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.59753456
73T cell receptor signaling pathway_Homo sapiens_hsa046600.58102907
74Systemic lupus erythematosus_Homo sapiens_hsa053220.57455138
75SNARE interactions in vesicular transport_Homo sapiens_hsa041300.56993889
76Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.53613071
77Tryptophan metabolism_Homo sapiens_hsa003800.52007975
78Caffeine metabolism_Homo sapiens_hsa002320.50850056
79Fat digestion and absorption_Homo sapiens_hsa049750.49545689
80Regulation of autophagy_Homo sapiens_hsa041400.46589542
81Serotonergic synapse_Homo sapiens_hsa047260.43976897
82Glutathione metabolism_Homo sapiens_hsa004800.43884756
83Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39757633
84Morphine addiction_Homo sapiens_hsa050320.37869455
85Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.37703902
86Salivary secretion_Homo sapiens_hsa049700.37464625
87Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.37177743
88NOD-like receptor signaling pathway_Homo sapiens_hsa046210.34142110
89Viral myocarditis_Homo sapiens_hsa054160.33908051
90Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.32129064
91Circadian entrainment_Homo sapiens_hsa047130.30424466
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.29699422
93Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.27851291
94Pyruvate metabolism_Homo sapiens_hsa006200.26005256
95Pancreatic secretion_Homo sapiens_hsa049720.25264165
96Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24821864
97ABC transporters_Homo sapiens_hsa020100.24023637
98Tyrosine metabolism_Homo sapiens_hsa003500.23052029
99Fatty acid elongation_Homo sapiens_hsa000620.21153194
100Sulfur relay system_Homo sapiens_hsa041220.20814339

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »