

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.95572039 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.95016781 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.95016781 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 6.93451071 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.09495077 |
| 6 | viral transcription (GO:0019083) | 5.70577852 |
| 7 | translational termination (GO:0006415) | 5.55359222 |
| 8 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.52942948 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 5.38076315 |
| 10 | respiratory electron transport chain (GO:0022904) | 5.14074710 |
| 11 | protein complex biogenesis (GO:0070271) | 5.09825066 |
| 12 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.08594687 |
| 13 | electron transport chain (GO:0022900) | 5.06064548 |
| 14 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.05096369 |
| 15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.05096369 |
| 16 | NADH dehydrogenase complex assembly (GO:0010257) | 5.05096369 |
| 17 | protein targeting to ER (GO:0045047) | 4.98929961 |
| 18 | cotranslational protein targeting to membrane (GO:0006613) | 4.97632589 |
| 19 | ribosomal small subunit biogenesis (GO:0042274) | 4.87032984 |
| 20 | translational elongation (GO:0006414) | 4.81944645 |
| 21 | DNA deamination (GO:0045006) | 4.79271394 |
| 22 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.76634621 |
| 23 | protein localization to endoplasmic reticulum (GO:0070972) | 4.74867727 |
| 24 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.69490089 |
| 25 | ribosomal large subunit biogenesis (GO:0042273) | 4.60632441 |
| 26 | protein neddylation (GO:0045116) | 4.34019489 |
| 27 | maturation of SSU-rRNA (GO:0030490) | 4.33330995 |
| 28 | cellular protein complex disassembly (GO:0043624) | 4.20170496 |
| 29 | viral life cycle (GO:0019058) | 4.15544118 |
| 30 | translational initiation (GO:0006413) | 4.06836130 |
| 31 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.03333217 |
| 32 | translation (GO:0006412) | 4.00163785 |
| 33 | respiratory chain complex IV assembly (GO:0008535) | 3.94489295 |
| 34 | ATP biosynthetic process (GO:0006754) | 3.91787340 |
| 35 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.84801378 |
| 36 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.81404034 |
| 37 | hydrogen ion transmembrane transport (GO:1902600) | 3.74479867 |
| 38 | proteasome assembly (GO:0043248) | 3.63188042 |
| 39 | GTP biosynthetic process (GO:0006183) | 3.62679167 |
| 40 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.61317911 |
| 41 | cytochrome complex assembly (GO:0017004) | 3.56334506 |
| 42 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.54653354 |
| 43 | termination of RNA polymerase III transcription (GO:0006386) | 3.54653354 |
| 44 | protein complex disassembly (GO:0043241) | 3.46847925 |
| 45 | cellular component biogenesis (GO:0044085) | 3.45332721 |
| 46 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.45329821 |
| 47 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.39330974 |
| 48 | macromolecular complex disassembly (GO:0032984) | 3.36074463 |
| 49 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35787362 |
| 50 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35787362 |
| 51 | protein targeting to membrane (GO:0006612) | 3.34610419 |
| 52 | proton transport (GO:0015992) | 3.34394341 |
| 53 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.33368669 |
| 54 | peptidyl-histidine modification (GO:0018202) | 3.32156986 |
| 55 | hydrogen transport (GO:0006818) | 3.28120162 |
| 56 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.27062308 |
| 57 | oxidative phosphorylation (GO:0006119) | 3.18645656 |
| 58 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.14750863 |
| 59 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.07601668 |
| 60 | aldehyde catabolic process (GO:0046185) | 3.07090702 |
| 61 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.05384829 |
| 62 | UTP metabolic process (GO:0046051) | 3.04930142 |
| 63 | UTP biosynthetic process (GO:0006228) | 3.04493477 |
| 64 | deoxyribose phosphate catabolic process (GO:0046386) | 3.01485913 |
| 65 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.99994334 |
| 66 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.96926340 |
| 67 | intracellular protein transmembrane import (GO:0044743) | 2.95832921 |
| 68 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.94833326 |
| 69 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.94652600 |
| 70 | mannosylation (GO:0097502) | 2.93976852 |
| 71 | protein-cofactor linkage (GO:0018065) | 2.91333051 |
| 72 | deoxyribonucleotide catabolic process (GO:0009264) | 2.89456315 |
| 73 | mRNA catabolic process (GO:0006402) | 2.89353360 |
| 74 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.87848224 |
| 75 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.87848224 |
| 76 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.87848224 |
| 77 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.85739373 |
| 78 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.85732350 |
| 79 | negative regulation of ligase activity (GO:0051352) | 2.85732350 |
| 80 | protein targeting to mitochondrion (GO:0006626) | 2.85576864 |
| 81 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.85177091 |
| 82 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.85177091 |
| 83 | rRNA processing (GO:0006364) | 2.82754772 |
| 84 | viral mRNA export from host cell nucleus (GO:0046784) | 2.82158243 |
| 85 | regulation of mitochondrial translation (GO:0070129) | 2.82063533 |
| 86 | protein localization to mitochondrion (GO:0070585) | 2.82017017 |
| 87 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.81919788 |
| 88 | establishment of protein localization to mitochondrion (GO:0072655) | 2.81537706 |
| 89 | rRNA metabolic process (GO:0016072) | 2.76022234 |
| 90 | rRNA modification (GO:0000154) | 2.75721189 |
| 91 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.74288754 |
| 92 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.74288754 |
| 93 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.74177064 |
| 94 | platelet dense granule organization (GO:0060155) | 2.73862611 |
| 95 | RNA catabolic process (GO:0006401) | 2.73459252 |
| 96 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.72035116 |
| 97 | behavioral response to nicotine (GO:0035095) | 2.69461612 |
| 98 | base-excision repair, AP site formation (GO:0006285) | 2.68684917 |
| 99 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.67490331 |
| 100 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.67351602 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.57235847 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.46080744 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.38881824 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.86793115 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.13933406 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.12075518 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.05189944 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.73768374 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.69658745 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.63892110 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.63357849 |
| 12 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.50085453 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.39888850 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.37423600 |
| 15 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.24304409 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.21115926 |
| 17 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.16289954 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.13098355 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04578705 |
| 20 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.99445514 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.99041707 |
| 22 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.98514027 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.88721141 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.82595619 |
| 25 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.70004800 |
| 26 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.69645745 |
| 27 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.66684889 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.65713859 |
| 29 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.63362378 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.63311423 |
| 31 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.62908363 |
| 32 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.61564297 |
| 33 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.56511818 |
| 34 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.56415304 |
| 35 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.56127589 |
| 36 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49001500 |
| 37 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.48939598 |
| 38 | EWS_26573619_Chip-Seq_HEK293_Human | 1.48102453 |
| 39 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43680013 |
| 40 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.38681613 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.37436828 |
| 42 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.36213297 |
| 43 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.32774493 |
| 44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.31207774 |
| 45 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.27891819 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.27840735 |
| 47 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.27548060 |
| 48 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.27442878 |
| 49 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.26260277 |
| 50 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24592793 |
| 51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24592793 |
| 52 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.24558646 |
| 53 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.22614237 |
| 54 | FUS_26573619_Chip-Seq_HEK293_Human | 1.21820817 |
| 55 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.19372366 |
| 56 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.17871807 |
| 57 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.16944354 |
| 58 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.15706755 |
| 59 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.14991380 |
| 60 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13758007 |
| 61 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13680245 |
| 62 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13568849 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.12825597 |
| 64 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.12622446 |
| 65 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.12581135 |
| 66 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.11685967 |
| 67 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.11051170 |
| 68 | AR_20517297_ChIP-Seq_VCAP_Human | 1.09578690 |
| 69 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08849180 |
| 70 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.06397821 |
| 71 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.05802559 |
| 72 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.05678116 |
| 73 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.04991592 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 1.04422195 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.03722881 |
| 76 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03699690 |
| 77 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.03582202 |
| 78 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.03571435 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.03571435 |
| 80 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01136937 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00323396 |
| 82 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.99535375 |
| 83 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.98558738 |
| 84 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.97812535 |
| 85 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.97215342 |
| 86 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.95545537 |
| 87 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.93749517 |
| 88 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.92166015 |
| 89 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.91615906 |
| 90 | P300_19829295_ChIP-Seq_ESCs_Human | 0.90804545 |
| 91 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.90016284 |
| 92 | ERA_21632823_ChIP-Seq_H3396_Human | 0.89995843 |
| 93 | GATA3_26560356_Chip-Seq_TH2_Human | 0.88799426 |
| 94 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.88129839 |
| 95 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87923477 |
| 96 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.87896399 |
| 97 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.87313268 |
| 98 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.87178299 |
| 99 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.87112330 |
| 100 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.87086436 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.39512897 |
| 2 | MP0006292_abnormal_olfactory_placode | 3.09644035 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.07535785 |
| 4 | MP0005671_abnormal_response_to | 2.97247926 |
| 5 | MP0002102_abnormal_ear_morphology | 2.64891943 |
| 6 | MP0004142_abnormal_muscle_tone | 2.61010861 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 2.37102470 |
| 8 | MP0000372_irregular_coat_pigmentation | 2.31645182 |
| 9 | MP0003646_muscle_fatigue | 2.28959917 |
| 10 | MP0003806_abnormal_nucleotide_metabolis | 2.26100842 |
| 11 | MP0002837_dystrophic_cardiac_calcinosis | 2.16947904 |
| 12 | MP0005360_urolithiasis | 2.05895437 |
| 13 | MP0008872_abnormal_physiological_respon | 2.03780405 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 1.99916343 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 1.98710416 |
| 16 | MP0002163_abnormal_gland_morphology | 1.91786935 |
| 17 | MP0003880_abnormal_central_pattern | 1.90791826 |
| 18 | MP0002876_abnormal_thyroid_physiology | 1.84444291 |
| 19 | MP0002638_abnormal_pupillary_reflex | 1.77967629 |
| 20 | MP0001968_abnormal_touch/_nociception | 1.75378832 |
| 21 | MP0009333_abnormal_splenocyte_physiolog | 1.67371739 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.64989551 |
| 23 | MP0004043_abnormal_pH_regulation | 1.62111430 |
| 24 | MP0005645_abnormal_hypothalamus_physiol | 1.60489563 |
| 25 | MP0003186_abnormal_redox_activity | 1.59364676 |
| 26 | MP0005084_abnormal_gallbladder_morpholo | 1.58576758 |
| 27 | MP0001986_abnormal_taste_sensitivity | 1.56928433 |
| 28 | MP0002938_white_spotting | 1.54729681 |
| 29 | MP0001905_abnormal_dopamine_level | 1.51953765 |
| 30 | MP0005379_endocrine/exocrine_gland_phen | 1.47354000 |
| 31 | MP0003787_abnormal_imprinting | 1.46080254 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.45117343 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.43629003 |
| 34 | MP0001529_abnormal_vocalization | 1.42714504 |
| 35 | MP0008877_abnormal_DNA_methylation | 1.42193967 |
| 36 | MP0001348_abnormal_lacrimal_gland | 1.41172611 |
| 37 | MP0001873_stomach_inflammation | 1.39820677 |
| 38 | MP0008875_abnormal_xenobiotic_pharmacok | 1.39714673 |
| 39 | MP0008058_abnormal_DNA_repair | 1.39643910 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.38875519 |
| 41 | MP0003878_abnormal_ear_physiology | 1.36983863 |
| 42 | MP0005377_hearing/vestibular/ear_phenot | 1.36983863 |
| 43 | MP0008789_abnormal_olfactory_epithelium | 1.35849769 |
| 44 | MP0001800_abnormal_humoral_immune | 1.35163268 |
| 45 | MP0002234_abnormal_pharynx_morphology | 1.29571544 |
| 46 | MP0005075_abnormal_melanosome_morpholog | 1.29126170 |
| 47 | MP0002736_abnormal_nociception_after | 1.25573172 |
| 48 | MP0002095_abnormal_skin_pigmentation | 1.25015000 |
| 49 | MP0004885_abnormal_endolymph | 1.23948429 |
| 50 | MP0006276_abnormal_autonomic_nervous | 1.23380150 |
| 51 | MP0002272_abnormal_nervous_system | 1.22308238 |
| 52 | MP0001919_abnormal_reproductive_system | 1.19055664 |
| 53 | MP0002166_altered_tumor_susceptibility | 1.16123113 |
| 54 | MP0005670_abnormal_white_adipose | 1.11693335 |
| 55 | MP0001970_abnormal_pain_threshold | 1.10103110 |
| 56 | MP0002733_abnormal_thermal_nociception | 1.09952504 |
| 57 | MP0001440_abnormal_grooming_behavior | 1.09418253 |
| 58 | MP0005253_abnormal_eye_physiology | 1.08102003 |
| 59 | MP0009745_abnormal_behavioral_response | 1.06965534 |
| 60 | MP0009785_altered_susceptibility_to | 1.05053331 |
| 61 | MP0003693_abnormal_embryo_hatching | 1.03841482 |
| 62 | MP0002006_tumorigenesis | 1.01697019 |
| 63 | MP0005387_immune_system_phenotype | 1.00023106 |
| 64 | MP0001790_abnormal_immune_system | 1.00023106 |
| 65 | MP0003136_yellow_coat_color | 0.96997873 |
| 66 | MP0004147_increased_porphyrin_level | 0.96490194 |
| 67 | MP0002148_abnormal_hypersensitivity_rea | 0.96344037 |
| 68 | MP0005389_reproductive_system_phenotype | 0.95800650 |
| 69 | MP0000685_abnormal_immune_system | 0.95100406 |
| 70 | MP0001485_abnormal_pinna_reflex | 0.92805886 |
| 71 | MP0003786_premature_aging | 0.92185936 |
| 72 | MP0003121_genomic_imprinting | 0.87579661 |
| 73 | MP0006035_abnormal_mitochondrial_morpho | 0.86491215 |
| 74 | MP0003123_paternal_imprinting | 0.86441222 |
| 75 | MP0001984_abnormal_olfaction | 0.85630313 |
| 76 | MP0005394_taste/olfaction_phenotype | 0.85236288 |
| 77 | MP0005499_abnormal_olfactory_system | 0.85236288 |
| 78 | MP0009764_decreased_sensitivity_to | 0.83315414 |
| 79 | MP0005332_abnormal_amino_acid | 0.82004841 |
| 80 | MP0003195_calcinosis | 0.81495440 |
| 81 | MP0005000_abnormal_immune_tolerance | 0.80994900 |
| 82 | MP0002735_abnormal_chemical_nociception | 0.80960471 |
| 83 | MP0000631_abnormal_neuroendocrine_gland | 0.80791000 |
| 84 | MP0001486_abnormal_startle_reflex | 0.80675263 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.80406302 |
| 86 | MP0003718_maternal_effect | 0.77477059 |
| 87 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77094686 |
| 88 | MP0010094_abnormal_chromosome_stability | 0.75397726 |
| 89 | MP0004133_heterotaxia | 0.74956490 |
| 90 | MP0002723_abnormal_immune_serum | 0.73981842 |
| 91 | MP0002653_abnormal_ependyma_morphology | 0.73649215 |
| 92 | MP0005174_abnormal_tail_pigmentation | 0.72827269 |
| 93 | MP0001188_hyperpigmentation | 0.71800681 |
| 94 | MP0005636_abnormal_mineral_homeostasis | 0.71533967 |
| 95 | MP0009046_muscle_twitch | 0.69946475 |
| 96 | MP0001661_extended_life_span | 0.68191023 |
| 97 | MP0002452_abnormal_antigen_presenting | 0.68118921 |
| 98 | MP0001293_anophthalmia | 0.67390172 |
| 99 | MP0000049_abnormal_middle_ear | 0.66837122 |
| 100 | MP0001764_abnormal_homeostasis | 0.65977998 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.86342277 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 5.24969232 |
| 3 | Mitochondrial inheritance (HP:0001427) | 5.21640946 |
| 4 | Acute encephalopathy (HP:0006846) | 4.86094005 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.79231389 |
| 6 | Increased CSF lactate (HP:0002490) | 4.76255730 |
| 7 | Hepatocellular necrosis (HP:0001404) | 4.58259123 |
| 8 | Hepatic necrosis (HP:0002605) | 4.15774397 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 4.07594824 |
| 10 | Cerebral edema (HP:0002181) | 3.88136531 |
| 11 | Lipid accumulation in hepatocytes (HP:0006561) | 3.84960780 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.70322322 |
| 13 | Reticulocytopenia (HP:0001896) | 3.34331000 |
| 14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.27740753 |
| 15 | Increased serum lactate (HP:0002151) | 3.23225570 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.22486243 |
| 17 | Optic disc pallor (HP:0000543) | 3.18548521 |
| 18 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.16122070 |
| 19 | Lactic acidosis (HP:0003128) | 2.95085276 |
| 20 | Leukodystrophy (HP:0002415) | 2.92173337 |
| 21 | Respiratory failure (HP:0002878) | 2.90499368 |
| 22 | B lymphocytopenia (HP:0010976) | 2.89337138 |
| 23 | Exertional dyspnea (HP:0002875) | 2.85039570 |
| 24 | Increased intramyocellular lipid droplets (HP:0012240) | 2.83435308 |
| 25 | Pancreatic cysts (HP:0001737) | 2.82636259 |
| 26 | Abnormality of midbrain morphology (HP:0002418) | 2.81690372 |
| 27 | Molar tooth sign on MRI (HP:0002419) | 2.81690372 |
| 28 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.73450478 |
| 29 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.72479291 |
| 30 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.72479291 |
| 31 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.69307486 |
| 32 | Macrocytic anemia (HP:0001972) | 2.66069556 |
| 33 | Abnormality of B cell number (HP:0010975) | 2.61595641 |
| 34 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.58271651 |
| 35 | Exercise intolerance (HP:0003546) | 2.52787576 |
| 36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.50521013 |
| 37 | Nephronophthisis (HP:0000090) | 2.46814488 |
| 38 | Lethargy (HP:0001254) | 2.43618798 |
| 39 | Increased muscle lipid content (HP:0009058) | 2.42895219 |
| 40 | Pancreatic fibrosis (HP:0100732) | 2.38999745 |
| 41 | Hypoproteinemia (HP:0003075) | 2.36958486 |
| 42 | True hermaphroditism (HP:0010459) | 2.33455323 |
| 43 | Aplastic anemia (HP:0001915) | 2.30295981 |
| 44 | Abolished electroretinogram (ERG) (HP:0000550) | 2.29623561 |
| 45 | Type II lissencephaly (HP:0007260) | 2.28963924 |
| 46 | Congenital stationary night blindness (HP:0007642) | 2.28644162 |
| 47 | Abnormality of urine glucose concentration (HP:0011016) | 2.26139615 |
| 48 | Glycosuria (HP:0003076) | 2.26139615 |
| 49 | Abnormal number of erythroid precursors (HP:0012131) | 2.25650727 |
| 50 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.25314886 |
| 51 | Absent/shortened dynein arms (HP:0200106) | 2.25314886 |
| 52 | Abnormality of renal resorption (HP:0011038) | 2.23893541 |
| 53 | Panhypogammaglobulinemia (HP:0003139) | 2.21679274 |
| 54 | Respiratory difficulties (HP:0002880) | 2.20833970 |
| 55 | Pallor (HP:0000980) | 2.20597401 |
| 56 | IgG deficiency (HP:0004315) | 2.19790983 |
| 57 | CNS demyelination (HP:0007305) | 2.18166682 |
| 58 | Methylmalonic aciduria (HP:0012120) | 2.17893661 |
| 59 | Constricted visual fields (HP:0001133) | 2.11192887 |
| 60 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.02565406 |
| 61 | Asplenia (HP:0001746) | 2.01978945 |
| 62 | Severe combined immunodeficiency (HP:0004430) | 2.01732896 |
| 63 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.00603757 |
| 64 | Parakeratosis (HP:0001036) | 1.99839674 |
| 65 | Medial flaring of the eyebrow (HP:0010747) | 1.99738836 |
| 66 | Methylmalonic acidemia (HP:0002912) | 1.99204528 |
| 67 | Chronic sinusitis (HP:0011109) | 1.98521499 |
| 68 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.98156727 |
| 69 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.98156727 |
| 70 | Cleft eyelid (HP:0000625) | 1.96551635 |
| 71 | Abnormality of the renal medulla (HP:0100957) | 1.93752585 |
| 72 | Absent thumb (HP:0009777) | 1.91937912 |
| 73 | Type 2 muscle fiber atrophy (HP:0003554) | 1.88877661 |
| 74 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.87671014 |
| 75 | Progressive microcephaly (HP:0000253) | 1.86830056 |
| 76 | Supernumerary spleens (HP:0009799) | 1.86728518 |
| 77 | Failure to thrive in infancy (HP:0001531) | 1.86367331 |
| 78 | Generalized aminoaciduria (HP:0002909) | 1.82285971 |
| 79 | Thyroiditis (HP:0100646) | 1.82051396 |
| 80 | Delayed CNS myelination (HP:0002188) | 1.81212527 |
| 81 | Microvesicular hepatic steatosis (HP:0001414) | 1.80725743 |
| 82 | Pendular nystagmus (HP:0012043) | 1.79881423 |
| 83 | Abnormal ciliary motility (HP:0012262) | 1.78849039 |
| 84 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.78323145 |
| 85 | Cerebellar dysplasia (HP:0007033) | 1.75272770 |
| 86 | Attenuation of retinal blood vessels (HP:0007843) | 1.75137832 |
| 87 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.74794075 |
| 88 | Dicarboxylic aciduria (HP:0003215) | 1.74443040 |
| 89 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.74443040 |
| 90 | Hypomagnesemia (HP:0002917) | 1.73416568 |
| 91 | Cerebral hypomyelination (HP:0006808) | 1.73116078 |
| 92 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.72800807 |
| 93 | Abnormality of magnesium homeostasis (HP:0004921) | 1.71126312 |
| 94 | Polydipsia (HP:0001959) | 1.70568287 |
| 95 | Abnormal drinking behavior (HP:0030082) | 1.70568287 |
| 96 | Abnormality of the renal cortex (HP:0011035) | 1.68434820 |
| 97 | X-linked dominant inheritance (HP:0001423) | 1.67169880 |
| 98 | Hyperphosphaturia (HP:0003109) | 1.66815111 |
| 99 | Emotional lability (HP:0000712) | 1.66792680 |
| 100 | Sclerocornea (HP:0000647) | 1.64650450 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TLK1 | 3.45223126 |
| 2 | MAP3K12 | 3.20944627 |
| 3 | ZAK | 3.10713358 |
| 4 | CDK19 | 3.07957659 |
| 5 | BMPR1B | 2.67197247 |
| 6 | STK16 | 2.52178846 |
| 7 | VRK2 | 2.22896832 |
| 8 | ADRBK2 | 2.16980643 |
| 9 | BCKDK | 2.09521923 |
| 10 | TXK | 2.08031173 |
| 11 | WNK4 | 2.01866551 |
| 12 | DYRK2 | 1.92088125 |
| 13 | CDK8 | 1.91165676 |
| 14 | GRK1 | 1.85558642 |
| 15 | BMPR2 | 1.81694023 |
| 16 | MAP4K2 | 1.80975097 |
| 17 | NUAK1 | 1.69654585 |
| 18 | VRK1 | 1.65456999 |
| 19 | CDC7 | 1.65072783 |
| 20 | WNK3 | 1.59130798 |
| 21 | EIF2AK3 | 1.58792205 |
| 22 | TAOK3 | 1.52677139 |
| 23 | NME1 | 1.44995715 |
| 24 | FRK | 1.31297347 |
| 25 | PIK3CG | 1.27339473 |
| 26 | TRIM28 | 1.27227711 |
| 27 | BUB1 | 1.25872559 |
| 28 | PINK1 | 1.25430563 |
| 29 | MYLK | 1.25412014 |
| 30 | PLK4 | 1.24960014 |
| 31 | OXSR1 | 1.23524051 |
| 32 | MAP4K1 | 1.21676385 |
| 33 | SCYL2 | 1.21326428 |
| 34 | ILK | 1.18603388 |
| 35 | MST4 | 1.17741925 |
| 36 | KDR | 1.12550010 |
| 37 | DAPK3 | 1.12541698 |
| 38 | NME2 | 1.09118677 |
| 39 | NEK1 | 1.05903711 |
| 40 | TEC | 1.04180054 |
| 41 | LIMK1 | 1.01788158 |
| 42 | SRPK1 | 1.01409196 |
| 43 | ITK | 1.00466191 |
| 44 | DAPK1 | 0.91182823 |
| 45 | PHKG1 | 0.90721286 |
| 46 | PHKG2 | 0.90721286 |
| 47 | ABL2 | 0.90361229 |
| 48 | STK39 | 0.89968664 |
| 49 | TNIK | 0.86588706 |
| 50 | TAF1 | 0.85648353 |
| 51 | MAP3K4 | 0.85572847 |
| 52 | TGFBR1 | 0.84817148 |
| 53 | PRKCG | 0.76405311 |
| 54 | SYK | 0.76238143 |
| 55 | RPS6KA5 | 0.75199975 |
| 56 | CSF1R | 0.71100653 |
| 57 | INSRR | 0.71030786 |
| 58 | TESK2 | 0.70384323 |
| 59 | ADRBK1 | 0.68873742 |
| 60 | ATR | 0.68177207 |
| 61 | MAPK13 | 0.67939333 |
| 62 | PRKCQ | 0.67084848 |
| 63 | RPS6KA4 | 0.66722561 |
| 64 | PLK3 | 0.65322858 |
| 65 | GRK6 | 0.63834158 |
| 66 | BCR | 0.63236141 |
| 67 | PASK | 0.61111796 |
| 68 | CSNK2A2 | 0.59837584 |
| 69 | CSNK1G2 | 0.59475651 |
| 70 | PRKCE | 0.58244703 |
| 71 | MKNK2 | 0.57843321 |
| 72 | DYRK3 | 0.57470255 |
| 73 | MINK1 | 0.56527470 |
| 74 | EIF2AK1 | 0.56495267 |
| 75 | EIF2AK2 | 0.56071592 |
| 76 | MAP2K6 | 0.55901929 |
| 77 | BTK | 0.55803228 |
| 78 | MKNK1 | 0.55670283 |
| 79 | AURKB | 0.54223475 |
| 80 | TSSK6 | 0.53607603 |
| 81 | ERBB3 | 0.51552397 |
| 82 | CSNK2A1 | 0.50643797 |
| 83 | DAPK2 | 0.50059038 |
| 84 | PBK | 0.48901047 |
| 85 | PLK1 | 0.48874265 |
| 86 | CSNK1G3 | 0.47640847 |
| 87 | RIPK4 | 0.47603806 |
| 88 | LYN | 0.47521738 |
| 89 | CASK | 0.45124716 |
| 90 | MAP2K7 | 0.44522945 |
| 91 | FLT3 | 0.44244883 |
| 92 | MARK1 | 0.43914949 |
| 93 | CAMK1 | 0.43673849 |
| 94 | MUSK | 0.43354007 |
| 95 | PRKACA | 0.42524655 |
| 96 | KIT | 0.41621708 |
| 97 | IKBKB | 0.41523536 |
| 98 | OBSCN | 0.40952862 |
| 99 | PKN1 | 0.39769008 |
| 100 | LCK | 0.39450894 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.54760479 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.37363186 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.81705203 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.79420267 |
| 5 | Asthma_Homo sapiens_hsa05310 | 3.41591590 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.78572244 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.67413011 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.61016028 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.49037834 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.48025314 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.44164894 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.40154330 |
| 13 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.20817607 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.17813246 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.13270429 |
| 16 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.04975967 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.71992816 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.60105973 |
| 19 | DNA replication_Homo sapiens_hsa03030 | 1.43634041 |
| 20 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.40801276 |
| 21 | Phototransduction_Homo sapiens_hsa04744 | 1.38022960 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.35390370 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.32172721 |
| 24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.29625245 |
| 25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.24126069 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.22526535 |
| 27 | Mismatch repair_Homo sapiens_hsa03430 | 1.15805759 |
| 28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.15610238 |
| 29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.10475595 |
| 30 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.09314884 |
| 31 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.07914902 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.07097469 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.05897998 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.03917423 |
| 35 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.03436945 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 0.97896925 |
| 37 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.97426730 |
| 38 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.95960236 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 0.95924217 |
| 40 | Basal transcription factors_Homo sapiens_hsa03022 | 0.93825785 |
| 41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.93149280 |
| 42 | Base excision repair_Homo sapiens_hsa03410 | 0.91914114 |
| 43 | Sulfur relay system_Homo sapiens_hsa04122 | 0.91162595 |
| 44 | RNA transport_Homo sapiens_hsa03013 | 0.90921758 |
| 45 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.87208874 |
| 46 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.84172126 |
| 47 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.81086968 |
| 48 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.79435771 |
| 49 | Viral myocarditis_Homo sapiens_hsa05416 | 0.79262135 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.78191758 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.74114327 |
| 52 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74090363 |
| 53 | Olfactory transduction_Homo sapiens_hsa04740 | 0.73197515 |
| 54 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.66767773 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.64342670 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63952469 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62528701 |
| 58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.62112250 |
| 59 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.59254417 |
| 60 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.58571385 |
| 61 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.57885934 |
| 62 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.51960654 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51915818 |
| 64 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.51624838 |
| 65 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.51307649 |
| 66 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.50706619 |
| 67 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.48958262 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.48506680 |
| 69 | Nicotine addiction_Homo sapiens_hsa05033 | 0.48112795 |
| 70 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46749084 |
| 71 | Morphine addiction_Homo sapiens_hsa05032 | 0.46636471 |
| 72 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.44754725 |
| 73 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44091417 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43997134 |
| 75 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42703363 |
| 76 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.41971195 |
| 77 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.41864608 |
| 78 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40896915 |
| 79 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39672875 |
| 80 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39376477 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36607191 |
| 82 | Retinol metabolism_Homo sapiens_hsa00830 | 0.34023358 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32965097 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.32953842 |
| 85 | Taste transduction_Homo sapiens_hsa04742 | 0.32621327 |
| 86 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30200275 |
| 87 | Leishmaniasis_Homo sapiens_hsa05140 | 0.28807072 |
| 88 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.27650581 |
| 89 | GABAergic synapse_Homo sapiens_hsa04727 | 0.27170164 |
| 90 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.26502504 |
| 91 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.25679871 |
| 92 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.25662505 |
| 93 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.25280885 |
| 94 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.24123971 |
| 95 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.22647185 |
| 96 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.20198740 |
| 97 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.19546059 |
| 98 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.18418782 |
| 99 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.18153742 |
| 100 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.17809944 |

