

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 6.93749315 |
| 2 | behavioral response to nicotine (GO:0035095) | 6.30709085 |
| 3 | viral transcription (GO:0019083) | 6.04992514 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 5.94030443 |
| 5 | translational termination (GO:0006415) | 5.76271129 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 5.33792060 |
| 7 | ribosomal small subunit biogenesis (GO:0042274) | 5.12302251 |
| 8 | response to pheromone (GO:0019236) | 4.93002853 |
| 9 | translational elongation (GO:0006414) | 4.89463864 |
| 10 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.81637897 |
| 11 | pattern specification involved in kidney development (GO:0061004) | 4.76776953 |
| 12 | protein targeting to ER (GO:0045047) | 4.73035258 |
| 13 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.71821737 |
| 14 | cotranslational protein targeting to membrane (GO:0006613) | 4.68558034 |
| 15 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.66099791 |
| 16 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.52280033 |
| 17 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.44572222 |
| 18 | viral life cycle (GO:0019058) | 4.43657974 |
| 19 | protein localization to endoplasmic reticulum (GO:0070972) | 4.41676498 |
| 20 | cellular protein complex disassembly (GO:0043624) | 4.39880681 |
| 21 | head development (GO:0060322) | 4.32485442 |
| 22 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.26103975 |
| 23 | ATP synthesis coupled proton transport (GO:0015986) | 4.26103975 |
| 24 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.20285364 |
| 25 | synaptic transmission, cholinergic (GO:0007271) | 4.04238611 |
| 26 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.95017745 |
| 27 | translational initiation (GO:0006413) | 3.87800088 |
| 28 | protein complex biogenesis (GO:0070271) | 3.86137705 |
| 29 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.84071668 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.79848762 |
| 31 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.79848762 |
| 32 | NADH dehydrogenase complex assembly (GO:0010257) | 3.79848762 |
| 33 | protein complex disassembly (GO:0043241) | 3.77568222 |
| 34 | GTP biosynthetic process (GO:0006183) | 3.76009591 |
| 35 | kinetochore assembly (GO:0051382) | 3.71206081 |
| 36 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.63899600 |
| 37 | macromolecular complex disassembly (GO:0032984) | 3.57604404 |
| 38 | L-serine metabolic process (GO:0006563) | 3.57415904 |
| 39 | nucleobase catabolic process (GO:0046113) | 3.54427139 |
| 40 | DNA deamination (GO:0045006) | 3.44373705 |
| 41 | kinetochore organization (GO:0051383) | 3.39701805 |
| 42 | startle response (GO:0001964) | 3.38534312 |
| 43 | UTP biosynthetic process (GO:0006228) | 3.29520399 |
| 44 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.28345383 |
| 45 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.28345383 |
| 46 | nonmotile primary cilium assembly (GO:0035058) | 3.27119251 |
| 47 | protein targeting to membrane (GO:0006612) | 3.24094959 |
| 48 | negative regulation of telomere maintenance (GO:0032205) | 3.23288859 |
| 49 | motile cilium assembly (GO:0044458) | 3.13497954 |
| 50 | ovulation cycle (GO:0042698) | 3.11926504 |
| 51 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.11445761 |
| 52 | translation (GO:0006412) | 3.10207054 |
| 53 | kidney morphogenesis (GO:0060993) | 3.09454875 |
| 54 | ubiquinone biosynthetic process (GO:0006744) | 3.05465116 |
| 55 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.04378461 |
| 56 | UTP metabolic process (GO:0046051) | 3.02749888 |
| 57 | hypothalamus development (GO:0021854) | 3.00506625 |
| 58 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 2.99998065 |
| 59 | cellular component biogenesis (GO:0044085) | 2.98393360 |
| 60 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.98259872 |
| 61 | cell proliferation in forebrain (GO:0021846) | 2.94127647 |
| 62 | mRNA catabolic process (GO:0006402) | 2.92803849 |
| 63 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.89191810 |
| 64 | ribosomal large subunit biogenesis (GO:0042273) | 2.85102156 |
| 65 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.84915594 |
| 66 | segment specification (GO:0007379) | 2.81750087 |
| 67 | negative regulation of organelle assembly (GO:1902116) | 2.81519128 |
| 68 | protein neddylation (GO:0045116) | 2.80645133 |
| 69 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.80115016 |
| 70 | regulation of telomere maintenance (GO:0032204) | 2.79764241 |
| 71 | postsynaptic membrane organization (GO:0001941) | 2.79549796 |
| 72 | protein localization to cilium (GO:0061512) | 2.79114614 |
| 73 | epithelial cilium movement (GO:0003351) | 2.78751866 |
| 74 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.77739197 |
| 75 | establishment of mitochondrion localization (GO:0051654) | 2.76606357 |
| 76 | olfactory bulb development (GO:0021772) | 2.74969253 |
| 77 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.73971230 |
| 78 | positive regulation of neurological system process (GO:0031646) | 2.72174241 |
| 79 | ubiquinone metabolic process (GO:0006743) | 2.71446053 |
| 80 | RNA catabolic process (GO:0006401) | 2.71055833 |
| 81 | intraciliary transport (GO:0042073) | 2.69276872 |
| 82 | transmission of nerve impulse (GO:0019226) | 2.68485026 |
| 83 | regulation of female gonad development (GO:2000194) | 2.64614795 |
| 84 | positive regulation of fatty acid oxidation (GO:0046321) | 2.63866467 |
| 85 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.63748804 |
| 86 | tyrosine phosphorylation of STAT protein (GO:0007260) | 2.61727156 |
| 87 | Sertoli cell development (GO:0060009) | 2.60372092 |
| 88 | axonemal dynein complex assembly (GO:0070286) | 2.59116811 |
| 89 | regulation of mitochondrial translation (GO:0070129) | 2.56275724 |
| 90 | CTP biosynthetic process (GO:0006241) | 2.56028586 |
| 91 | CTP metabolic process (GO:0046036) | 2.56028586 |
| 92 | isoprenoid biosynthetic process (GO:0008299) | 2.55528012 |
| 93 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.55376159 |
| 94 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.55139103 |
| 95 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.54906971 |
| 96 | regulation of transmission of nerve impulse (GO:0051969) | 2.52202067 |
| 97 | estrogen biosynthetic process (GO:0006703) | 2.52004852 |
| 98 | regulation of action potential (GO:0098900) | 2.51300769 |
| 99 | replication fork processing (GO:0031297) | 2.50227628 |
| 100 | regulation of autophagic vacuole assembly (GO:2000785) | 2.49306198 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.81212389 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.64826559 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.88098141 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.80177980 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.44788945 |
| 6 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.19659327 |
| 7 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.01196669 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.92971315 |
| 9 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.91349412 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 1.89686735 |
| 11 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.88159085 |
| 12 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.83277414 |
| 13 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.82959109 |
| 14 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.80453681 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.79409141 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.78073495 |
| 17 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.76327136 |
| 18 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.75577075 |
| 19 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.72775586 |
| 20 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.70747849 |
| 21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.68354202 |
| 22 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.62550020 |
| 23 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.60028513 |
| 24 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.54052884 |
| 25 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.53077904 |
| 26 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.51700861 |
| 27 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.49611244 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.47629260 |
| 29 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.47603380 |
| 30 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.46792235 |
| 31 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.43693903 |
| 32 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.41121318 |
| 33 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.39553525 |
| 34 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.39517793 |
| 35 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.39290564 |
| 36 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.38818295 |
| 37 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.37681085 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.37595632 |
| 39 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.35102506 |
| 40 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.32555781 |
| 41 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.32195594 |
| 42 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.31776896 |
| 43 | ERA_21632823_ChIP-Seq_H3396_Human | 1.31598824 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.31302774 |
| 45 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.28996108 |
| 46 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.28860845 |
| 47 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.28513702 |
| 48 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.27805403 |
| 49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.27435923 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.25722564 |
| 51 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25671009 |
| 52 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.25446611 |
| 53 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.25312120 |
| 54 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.25285775 |
| 55 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.25162728 |
| 56 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.25031644 |
| 57 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.23094042 |
| 58 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.21203290 |
| 59 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.20114460 |
| 60 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.19142637 |
| 61 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17578370 |
| 62 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.16449510 |
| 63 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.15048615 |
| 64 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.14212032 |
| 65 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.12810802 |
| 66 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12557937 |
| 67 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.10313636 |
| 68 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.09065461 |
| 69 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.08955967 |
| 70 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.08328433 |
| 71 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.07517532 |
| 72 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.06187981 |
| 73 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.05569776 |
| 74 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.05569776 |
| 75 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.04311669 |
| 76 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.02901086 |
| 77 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.01464276 |
| 78 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.01179214 |
| 79 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 1.01166854 |
| 80 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.99921880 |
| 81 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.99859139 |
| 82 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.98555530 |
| 83 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.98492276 |
| 84 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.97393162 |
| 85 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.97045103 |
| 86 | P300_19829295_ChIP-Seq_ESCs_Human | 0.96381555 |
| 87 | E2F1_17053090_ChIP-ChIP_MCF-7_Human | 0.96081769 |
| 88 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.95998506 |
| 89 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.95669632 |
| 90 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.95115620 |
| 91 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.94651034 |
| 92 | SOX2_22085726_ChIP-Seq_NPCs_Mouse | 0.93522828 |
| 93 | P68_20966046_ChIP-Seq_HELA_Human | 0.93459087 |
| 94 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.93030683 |
| 95 | SA1_27219007_Chip-Seq_Bcells_Human | 0.93011672 |
| 96 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91734304 |
| 97 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91734304 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.91262720 |
| 99 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 0.90808362 |
| 100 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.90279203 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.83180569 |
| 2 | MP0003122_maternal_imprinting | 4.03620950 |
| 3 | MP0003646_muscle_fatigue | 3.11088928 |
| 4 | MP0005646_abnormal_pituitary_gland | 3.09227199 |
| 5 | MP0003787_abnormal_imprinting | 2.86775590 |
| 6 | MP0004885_abnormal_endolymph | 2.79539934 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.75202423 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.72455507 |
| 9 | MP0004142_abnormal_muscle_tone | 2.68373673 |
| 10 | MP0003121_genomic_imprinting | 2.67712267 |
| 11 | MP0005377_hearing/vestibular/ear_phenot | 2.66304235 |
| 12 | MP0003878_abnormal_ear_physiology | 2.66304235 |
| 13 | MP0001529_abnormal_vocalization | 2.59617619 |
| 14 | MP0006276_abnormal_autonomic_nervous | 2.38597025 |
| 15 | MP0003136_yellow_coat_color | 2.36156568 |
| 16 | MP0003879_abnormal_hair_cell | 2.33664543 |
| 17 | MP0001348_abnormal_lacrimal_gland | 2.07226460 |
| 18 | MP0002102_abnormal_ear_morphology | 2.02416213 |
| 19 | MP0001440_abnormal_grooming_behavior | 1.95236504 |
| 20 | MP0001873_stomach_inflammation | 1.94069918 |
| 21 | MP0001485_abnormal_pinna_reflex | 1.91165965 |
| 22 | MP0001188_hyperpigmentation | 1.85352312 |
| 23 | MP0000049_abnormal_middle_ear | 1.85341062 |
| 24 | MP0002138_abnormal_hepatobiliary_system | 1.84358300 |
| 25 | MP0003567_abnormal_fetal_cardiomyocyte | 1.79023535 |
| 26 | MP0004742_abnormal_vestibular_system | 1.77992098 |
| 27 | MP0000778_abnormal_nervous_system | 1.73960151 |
| 28 | MP0008875_abnormal_xenobiotic_pharmacok | 1.69954487 |
| 29 | MP0008789_abnormal_olfactory_epithelium | 1.63843832 |
| 30 | MP0002557_abnormal_social/conspecific_i | 1.60155857 |
| 31 | MP0000631_abnormal_neuroendocrine_gland | 1.58912330 |
| 32 | MP0003315_abnormal_perineum_morphology | 1.49834807 |
| 33 | MP0008872_abnormal_physiological_respon | 1.47906102 |
| 34 | MP0002653_abnormal_ependyma_morphology | 1.44516886 |
| 35 | MP0005499_abnormal_olfactory_system | 1.43226530 |
| 36 | MP0005394_taste/olfaction_phenotype | 1.43226530 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.38617506 |
| 38 | MP0001968_abnormal_touch/_nociception | 1.27776760 |
| 39 | MP0004145_abnormal_muscle_electrophysio | 1.26306827 |
| 40 | MP0005386_behavior/neurological_phenoty | 1.26299980 |
| 41 | MP0004924_abnormal_behavior | 1.26299980 |
| 42 | MP0001984_abnormal_olfaction | 1.25334921 |
| 43 | MP0004133_heterotaxia | 1.24478114 |
| 44 | MP0002272_abnormal_nervous_system | 1.22907189 |
| 45 | MP0009745_abnormal_behavioral_response | 1.19447880 |
| 46 | MP0005084_abnormal_gallbladder_morpholo | 1.18961762 |
| 47 | MP0002063_abnormal_learning/memory/cond | 1.18125494 |
| 48 | MP0002938_white_spotting | 1.17954439 |
| 49 | MP0000613_abnormal_salivary_gland | 1.15345367 |
| 50 | MP0005423_abnormal_somatic_nervous | 1.12019866 |
| 51 | MP0001970_abnormal_pain_threshold | 1.11640888 |
| 52 | MP0000566_synostosis | 1.11211767 |
| 53 | MP0002733_abnormal_thermal_nociception | 1.10171304 |
| 54 | MP0000026_abnormal_inner_ear | 1.08974454 |
| 55 | MP0002638_abnormal_pupillary_reflex | 1.08676670 |
| 56 | MP0001963_abnormal_hearing_physiology | 1.05260633 |
| 57 | MP0003195_calcinosis | 1.04944839 |
| 58 | MP0001293_anophthalmia | 1.04676944 |
| 59 | MP0003880_abnormal_central_pattern | 1.03535803 |
| 60 | MP0003123_paternal_imprinting | 1.01452510 |
| 61 | MP0005408_hypopigmentation | 1.00686703 |
| 62 | MP0003635_abnormal_synaptic_transmissio | 1.00340632 |
| 63 | MP0002572_abnormal_emotion/affect_behav | 0.99700907 |
| 64 | MP0002876_abnormal_thyroid_physiology | 0.99530407 |
| 65 | MP0005389_reproductive_system_phenotype | 0.97420735 |
| 66 | MP0004147_increased_porphyrin_level | 0.96190706 |
| 67 | MP0001663_abnormal_digestive_system | 0.94956804 |
| 68 | MP0001486_abnormal_startle_reflex | 0.93736549 |
| 69 | MP0005167_abnormal_blood-brain_barrier | 0.93700041 |
| 70 | MP0002735_abnormal_chemical_nociception | 0.92259125 |
| 71 | MP0002067_abnormal_sensory_capabilities | 0.92129729 |
| 72 | MP0002184_abnormal_innervation | 0.91481783 |
| 73 | MP0005195_abnormal_posterior_eye | 0.91314444 |
| 74 | MP0008775_abnormal_heart_ventricle | 0.90521878 |
| 75 | MP0001905_abnormal_dopamine_level | 0.89704787 |
| 76 | MP0002234_abnormal_pharynx_morphology | 0.89067540 |
| 77 | MP0002064_seizures | 0.87861664 |
| 78 | MP0002736_abnormal_nociception_after | 0.87295411 |
| 79 | MP0009046_muscle_twitch | 0.86626549 |
| 80 | MP0000955_abnormal_spinal_cord | 0.85504243 |
| 81 | MP0005187_abnormal_penis_morphology | 0.85438659 |
| 82 | MP0002752_abnormal_somatic_nervous | 0.83401894 |
| 83 | MP0005670_abnormal_white_adipose | 0.83365100 |
| 84 | MP0003119_abnormal_digestive_system | 0.83234388 |
| 85 | MP0001919_abnormal_reproductive_system | 0.81438314 |
| 86 | MP0004859_abnormal_synaptic_plasticity | 0.79838042 |
| 87 | MP0009053_abnormal_anal_canal | 0.79624374 |
| 88 | MP0004043_abnormal_pH_regulation | 0.78552107 |
| 89 | MP0002163_abnormal_gland_morphology | 0.77686447 |
| 90 | MP0003942_abnormal_urinary_system | 0.77504327 |
| 91 | MP0002160_abnormal_reproductive_system | 0.77244526 |
| 92 | MP0002837_dystrophic_cardiac_calcinosis | 0.76653119 |
| 93 | MP0005645_abnormal_hypothalamus_physiol | 0.76538759 |
| 94 | MP0003937_abnormal_limbs/digits/tail_de | 0.76288134 |
| 95 | MP0008058_abnormal_DNA_repair | 0.74696602 |
| 96 | MP0002210_abnormal_sex_determination | 0.72271299 |
| 97 | MP0002734_abnormal_mechanical_nocicepti | 0.72026623 |
| 98 | MP0003011_delayed_dark_adaptation | 0.71434244 |
| 99 | MP0006035_abnormal_mitochondrial_morpho | 0.67792924 |
| 100 | MP0002152_abnormal_brain_morphology | 0.64393940 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.02358555 |
| 2 | Septo-optic dysplasia (HP:0100842) | 4.24042409 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.59131377 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 3.48370879 |
| 5 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.37625884 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.37123957 |
| 7 | Abnormality of DNA repair (HP:0003254) | 3.31265275 |
| 8 | Papilledema (HP:0001085) | 3.26931076 |
| 9 | Pancreatic fibrosis (HP:0100732) | 3.24633752 |
| 10 | Optic nerve hypoplasia (HP:0000609) | 3.22214282 |
| 11 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.21364662 |
| 12 | Asplenia (HP:0001746) | 3.16360265 |
| 13 | Acute encephalopathy (HP:0006846) | 3.09893479 |
| 14 | Abnormality of the labia minora (HP:0012880) | 3.07493958 |
| 15 | Ectopic kidney (HP:0000086) | 2.95050607 |
| 16 | Mitochondrial inheritance (HP:0001427) | 2.94523352 |
| 17 | Pancreatic cysts (HP:0001737) | 2.90077142 |
| 18 | Type II lissencephaly (HP:0007260) | 2.89406834 |
| 19 | Progressive macrocephaly (HP:0004481) | 2.87560245 |
| 20 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.84357997 |
| 21 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.82322192 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.79187620 |
| 23 | Macrocytic anemia (HP:0001972) | 2.74137402 |
| 24 | Growth hormone deficiency (HP:0000824) | 2.72984949 |
| 25 | Increased CSF lactate (HP:0002490) | 2.70483515 |
| 26 | Maternal diabetes (HP:0009800) | 2.70384665 |
| 27 | Lissencephaly (HP:0001339) | 2.65663504 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.64289481 |
| 29 | Absent/shortened dynein arms (HP:0200106) | 2.64289481 |
| 30 | Pachygyria (HP:0001302) | 2.60565407 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.57682206 |
| 32 | Molar tooth sign on MRI (HP:0002419) | 2.57682206 |
| 33 | Absent thumb (HP:0009777) | 2.45099223 |
| 34 | Rib fusion (HP:0000902) | 2.44978612 |
| 35 | Nephronophthisis (HP:0000090) | 2.44112458 |
| 36 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.43536256 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.42628659 |
| 38 | Hypoplasia of the radius (HP:0002984) | 2.41193480 |
| 39 | Pendular nystagmus (HP:0012043) | 2.39557231 |
| 40 | Anophthalmia (HP:0000528) | 2.39332591 |
| 41 | Morphological abnormality of the inner ear (HP:0011390) | 2.37251489 |
| 42 | Horseshoe kidney (HP:0000085) | 2.36517469 |
| 43 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.36073495 |
| 44 | True hermaphroditism (HP:0010459) | 2.34480054 |
| 45 | Absent septum pellucidum (HP:0001331) | 2.32796512 |
| 46 | Optic disc pallor (HP:0000543) | 2.26852408 |
| 47 | Cerebellar dysplasia (HP:0007033) | 2.23477246 |
| 48 | Increased muscle lipid content (HP:0009058) | 2.23040730 |
| 49 | Failure to thrive in infancy (HP:0001531) | 2.22363356 |
| 50 | Abnormality of cochlea (HP:0000375) | 2.22157320 |
| 51 | Pallor (HP:0000980) | 2.21629819 |
| 52 | Forearm undergrowth (HP:0009821) | 2.18276884 |
| 53 | Abnormality of the renal medulla (HP:0100957) | 2.18165287 |
| 54 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.16603705 |
| 55 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.16603705 |
| 56 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.15868928 |
| 57 | Increased serum lactate (HP:0002151) | 2.14393914 |
| 58 | Abnormal biliary tract physiology (HP:0012439) | 2.13541150 |
| 59 | Bile duct proliferation (HP:0001408) | 2.13541150 |
| 60 | Colon cancer (HP:0003003) | 2.10469072 |
| 61 | Hepatocellular necrosis (HP:0001404) | 2.10127608 |
| 62 | Medial flaring of the eyebrow (HP:0010747) | 2.07256715 |
| 63 | Oligodactyly (HP:0012165) | 2.05533697 |
| 64 | Hypoplastic pelvis (HP:0008839) | 2.04805350 |
| 65 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.04408143 |
| 66 | Congenital stationary night blindness (HP:0007642) | 2.04238747 |
| 67 | Hyperventilation (HP:0002883) | 2.04042375 |
| 68 | Progressive cerebellar ataxia (HP:0002073) | 2.03712078 |
| 69 | Hepatic necrosis (HP:0002605) | 2.02322456 |
| 70 | Hypoplasia of the ulna (HP:0003022) | 2.01719275 |
| 71 | Partial agenesis of the corpus callosum (HP:0001338) | 2.01697863 |
| 72 | Exertional dyspnea (HP:0002875) | 2.00849231 |
| 73 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.99094166 |
| 74 | Abnormal ciliary motility (HP:0012262) | 1.98701993 |
| 75 | Poor suck (HP:0002033) | 1.97448439 |
| 76 | Polyphagia (HP:0002591) | 1.97445468 |
| 77 | Anosmia (HP:0000458) | 1.96659133 |
| 78 | Abnormal number of incisors (HP:0011064) | 1.94196690 |
| 79 | Gait imbalance (HP:0002141) | 1.94188033 |
| 80 | Abnormality of the septum pellucidum (HP:0007375) | 1.93903737 |
| 81 | Oligodactyly (hands) (HP:0001180) | 1.93628679 |
| 82 | Abnormal drinking behavior (HP:0030082) | 1.93499791 |
| 83 | Polydipsia (HP:0001959) | 1.93499791 |
| 84 | Supernumerary spleens (HP:0009799) | 1.92635994 |
| 85 | Anencephaly (HP:0002323) | 1.86546236 |
| 86 | Decreased muscle mass (HP:0003199) | 1.85751229 |
| 87 | Hyperthyroidism (HP:0000836) | 1.85087377 |
| 88 | Abnormality of the renal cortex (HP:0011035) | 1.83364684 |
| 89 | Abnormality of renal resorption (HP:0011038) | 1.80463648 |
| 90 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.80457527 |
| 91 | Tubular atrophy (HP:0000092) | 1.80101647 |
| 92 | Cystic liver disease (HP:0006706) | 1.79341632 |
| 93 | Stenosis of the external auditory canal (HP:0000402) | 1.78978162 |
| 94 | Myokymia (HP:0002411) | 1.78948109 |
| 95 | Cerebral edema (HP:0002181) | 1.77769122 |
| 96 | Agitation (HP:0000713) | 1.77747502 |
| 97 | Oligomenorrhea (HP:0000876) | 1.76714568 |
| 98 | Abolished electroretinogram (ERG) (HP:0000550) | 1.76683561 |
| 99 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.76582867 |
| 100 | Respiratory difficulties (HP:0002880) | 1.75793054 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 5.38259391 |
| 2 | STK16 | 4.69741413 |
| 3 | DYRK2 | 3.28913596 |
| 4 | EPHB2 | 2.55040975 |
| 5 | NME1 | 2.54110487 |
| 6 | WNK4 | 2.52915927 |
| 7 | GRK1 | 2.41959338 |
| 8 | TNIK | 2.25919101 |
| 9 | BMPR1B | 2.21371722 |
| 10 | NUAK1 | 2.04983161 |
| 11 | PAK6 | 2.00389909 |
| 12 | CASK | 1.99299701 |
| 13 | TAOK3 | 1.95541773 |
| 14 | VRK2 | 1.87701828 |
| 15 | CAMK1D | 1.84314242 |
| 16 | PIK3CA | 1.69551665 |
| 17 | BCKDK | 1.65310131 |
| 18 | ADRBK2 | 1.56259774 |
| 19 | PIM2 | 1.41192165 |
| 20 | TAF1 | 1.40406262 |
| 21 | CAMKK2 | 1.38848957 |
| 22 | TYRO3 | 1.27265585 |
| 23 | STK39 | 1.17882361 |
| 24 | MARK1 | 1.15280093 |
| 25 | TGFBR1 | 1.13916461 |
| 26 | DAPK3 | 1.12159354 |
| 27 | DYRK1B | 1.11877528 |
| 28 | CAMK1G | 1.10918668 |
| 29 | NTRK2 | 1.09048546 |
| 30 | PDK2 | 1.07398967 |
| 31 | MAPK13 | 1.03824091 |
| 32 | EIF2AK1 | 1.01503247 |
| 33 | MAP4K2 | 1.00841298 |
| 34 | DAPK2 | 0.98388195 |
| 35 | PBK | 0.98255360 |
| 36 | CAMK1 | 0.97435472 |
| 37 | PAK3 | 0.96970918 |
| 38 | CDK8 | 0.94972547 |
| 39 | PRKCG | 0.91691235 |
| 40 | TXK | 0.91075555 |
| 41 | CDK19 | 0.89457171 |
| 42 | TSSK6 | 0.89338503 |
| 43 | CDC7 | 0.86755629 |
| 44 | MINK1 | 0.84803379 |
| 45 | NEK1 | 0.84605985 |
| 46 | PRKD3 | 0.83081401 |
| 47 | PLK2 | 0.81273259 |
| 48 | OBSCN | 0.81268760 |
| 49 | PHKG2 | 0.80789526 |
| 50 | PHKG1 | 0.80789526 |
| 51 | WNK3 | 0.72236876 |
| 52 | PRKCQ | 0.71698231 |
| 53 | OXSR1 | 0.70575460 |
| 54 | CCNB1 | 0.68237128 |
| 55 | PASK | 0.67748511 |
| 56 | PINK1 | 0.66947872 |
| 57 | FRK | 0.62635025 |
| 58 | PRKCI | 0.62228786 |
| 59 | LIMK1 | 0.61950710 |
| 60 | STK11 | 0.61655546 |
| 61 | EIF2AK2 | 0.60927890 |
| 62 | PLK3 | 0.59620770 |
| 63 | TEC | 0.57374554 |
| 64 | PRKCH | 0.56936786 |
| 65 | ALK | 0.56432031 |
| 66 | VRK1 | 0.56367089 |
| 67 | INSRR | 0.54708701 |
| 68 | PTK6 | 0.53766656 |
| 69 | SGK223 | 0.51925333 |
| 70 | SGK494 | 0.51925333 |
| 71 | LRRK2 | 0.50807527 |
| 72 | CSNK1E | 0.50699420 |
| 73 | TLK1 | 0.50204620 |
| 74 | SIK2 | 0.50197962 |
| 75 | AURKB | 0.48665920 |
| 76 | PLK1 | 0.48663489 |
| 77 | ERBB2 | 0.48415126 |
| 78 | WEE1 | 0.48391242 |
| 79 | SGK1 | 0.47858164 |
| 80 | CAMK2A | 0.46775837 |
| 81 | CSNK2A2 | 0.46535282 |
| 82 | CAMKK1 | 0.45610295 |
| 83 | FES | 0.45494994 |
| 84 | MAP2K7 | 0.45397904 |
| 85 | AURKA | 0.43745497 |
| 86 | MKNK2 | 0.43535439 |
| 87 | ZAK | 0.42615314 |
| 88 | RPS6KA6 | 0.41032589 |
| 89 | PRKCZ | 0.40938727 |
| 90 | AKT3 | 0.40877978 |
| 91 | CAMK4 | 0.39591403 |
| 92 | CHEK1 | 0.38885115 |
| 93 | PRKACA | 0.38671950 |
| 94 | ROCK1 | 0.38295354 |
| 95 | WNK1 | 0.38106430 |
| 96 | PKN1 | 0.37930787 |
| 97 | DMPK | 0.36706804 |
| 98 | ATR | 0.36175660 |
| 99 | KIT | 0.35914731 |
| 100 | PIK3CG | 0.35803159 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.77008684 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.25139421 |
| 3 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.96734744 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.79435141 |
| 5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.58276196 |
| 6 | RNA degradation_Homo sapiens_hsa03018 | 2.11691224 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.07735238 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.07636832 |
| 9 | Sulfur relay system_Homo sapiens_hsa04122 | 1.99401456 |
| 10 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.93747714 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 1.92916914 |
| 12 | Asthma_Homo sapiens_hsa05310 | 1.91970396 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.91758471 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.80425364 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79231455 |
| 16 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.78216855 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.74241825 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.70785310 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.64623836 |
| 20 | Peroxisome_Homo sapiens_hsa04146 | 1.62637587 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.60235732 |
| 22 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.55467063 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.55226644 |
| 24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.53292992 |
| 25 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.49601708 |
| 26 | Protein export_Homo sapiens_hsa03060 | 1.45922593 |
| 27 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.44006505 |
| 28 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.38489825 |
| 29 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.37763414 |
| 30 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.37173415 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.36253735 |
| 32 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.35202515 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.33013499 |
| 34 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.26954259 |
| 35 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.26566530 |
| 36 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.23224209 |
| 37 | Basal transcription factors_Homo sapiens_hsa03022 | 1.22652355 |
| 38 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.13117829 |
| 39 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.12986737 |
| 40 | Allograft rejection_Homo sapiens_hsa05330 | 1.11591221 |
| 41 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.04522520 |
| 42 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.00722828 |
| 43 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.00579129 |
| 44 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.00575727 |
| 45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.00570238 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99825884 |
| 47 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.99112271 |
| 48 | Olfactory transduction_Homo sapiens_hsa04740 | 0.94999059 |
| 49 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.92410284 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.90873441 |
| 51 | Proteasome_Homo sapiens_hsa03050 | 0.90540729 |
| 52 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.87288855 |
| 53 | DNA replication_Homo sapiens_hsa03030 | 0.84348570 |
| 54 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.83964629 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.83391433 |
| 56 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.81196499 |
| 57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.81139481 |
| 58 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.80891979 |
| 59 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.79350972 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.77566393 |
| 61 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.77356909 |
| 62 | Morphine addiction_Homo sapiens_hsa05032 | 0.74112119 |
| 63 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.73291496 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.73164324 |
| 65 | Mismatch repair_Homo sapiens_hsa03430 | 0.72273879 |
| 66 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.72101970 |
| 67 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.68695119 |
| 68 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.67363441 |
| 69 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.66609162 |
| 70 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64251042 |
| 71 | RNA transport_Homo sapiens_hsa03013 | 0.63578743 |
| 72 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.62641612 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 0.62461878 |
| 74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61250610 |
| 75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.57845923 |
| 76 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.53832239 |
| 77 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.52327473 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.49273135 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.47976542 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.47360137 |
| 81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45713441 |
| 82 | Axon guidance_Homo sapiens_hsa04360 | 0.45296509 |
| 83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.43660697 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.43424614 |
| 85 | Insulin secretion_Homo sapiens_hsa04911 | 0.40527428 |
| 86 | Mineral absorption_Homo sapiens_hsa04978 | 0.40226068 |
| 87 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.38114900 |
| 88 | GABAergic synapse_Homo sapiens_hsa04727 | 0.37559367 |
| 89 | Salivary secretion_Homo sapiens_hsa04970 | 0.37464864 |
| 90 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.32799931 |
| 91 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.27901754 |
| 92 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.27723434 |
| 93 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.27402152 |
| 94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.26030807 |
| 95 | Melanoma_Homo sapiens_hsa05218 | 0.24952152 |
| 96 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.23715398 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.22538305 |
| 98 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.22200780 |
| 99 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.18944686 |
| 100 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.18943293 |

