

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 6.54444504 |
| 2 | DNA deamination (GO:0045006) | 5.58089256 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.37380069 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.22780410 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.22780410 |
| 6 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.10940909 |
| 7 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.10940909 |
| 8 | base-excision repair, AP site formation (GO:0006285) | 4.65758242 |
| 9 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.55454611 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.44603110 |
| 11 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.35698153 |
| 12 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.27412973 |
| 13 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.15757580 |
| 14 | protein neddylation (GO:0045116) | 4.09428096 |
| 15 | maturation of SSU-rRNA (GO:0030490) | 4.08751640 |
| 16 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.05437899 |
| 17 | electron transport chain (GO:0022900) | 4.04945142 |
| 18 | respiratory electron transport chain (GO:0022904) | 4.03115198 |
| 19 | viral transcription (GO:0019083) | 3.89430077 |
| 20 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.88528996 |
| 21 | rRNA modification (GO:0000154) | 3.79209698 |
| 22 | translational termination (GO:0006415) | 3.77307582 |
| 23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.77268136 |
| 24 | respiratory chain complex IV assembly (GO:0008535) | 3.75901561 |
| 25 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.74323611 |
| 26 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.65506935 |
| 27 | protein complex biogenesis (GO:0070271) | 3.63990512 |
| 28 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.61828070 |
| 29 | ribosomal large subunit biogenesis (GO:0042273) | 3.60821334 |
| 30 | translational elongation (GO:0006414) | 3.55871514 |
| 31 | cotranslational protein targeting to membrane (GO:0006613) | 3.54834598 |
| 32 | protein targeting to ER (GO:0045047) | 3.52172955 |
| 33 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.50780613 |
| 34 | NADH dehydrogenase complex assembly (GO:0010257) | 3.50780613 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.50780613 |
| 36 | ribosomal small subunit biogenesis (GO:0042274) | 3.47416863 |
| 37 | rRNA methylation (GO:0031167) | 3.45384439 |
| 38 | cytochrome complex assembly (GO:0017004) | 3.42196533 |
| 39 | protein localization to endoplasmic reticulum (GO:0070972) | 3.39668544 |
| 40 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.39329607 |
| 41 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.35924058 |
| 42 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.35591857 |
| 43 | chaperone-mediated protein transport (GO:0072321) | 3.35218591 |
| 44 | negative regulation of ligase activity (GO:0051352) | 3.34971521 |
| 45 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.34971521 |
| 46 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.34322720 |
| 47 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.33736480 |
| 48 | proteasome assembly (GO:0043248) | 3.31979708 |
| 49 | translation (GO:0006412) | 3.31476240 |
| 50 | DNA damage response, detection of DNA damage (GO:0042769) | 3.30805959 |
| 51 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.27777941 |
| 52 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.27777941 |
| 53 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.27243876 |
| 54 | negative regulation of telomere maintenance (GO:0032205) | 3.26681852 |
| 55 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.26635973 |
| 56 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.26635973 |
| 57 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.26635973 |
| 58 | regulation of meiosis I (GO:0060631) | 3.22999948 |
| 59 | peptidyl-histidine modification (GO:0018202) | 3.22412928 |
| 60 | deoxyribonucleotide catabolic process (GO:0009264) | 3.21239221 |
| 61 | ubiquinone biosynthetic process (GO:0006744) | 3.17081476 |
| 62 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.16908502 |
| 63 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.16854602 |
| 64 | chromatin remodeling at centromere (GO:0031055) | 3.15260456 |
| 65 | DNA strand renaturation (GO:0000733) | 3.15146972 |
| 66 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.12974787 |
| 67 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.12974787 |
| 68 | protein polyglutamylation (GO:0018095) | 3.12213304 |
| 69 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.12139204 |
| 70 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.11263774 |
| 71 | termination of RNA polymerase III transcription (GO:0006386) | 3.11263774 |
| 72 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.09767148 |
| 73 | translational initiation (GO:0006413) | 3.08977516 |
| 74 | CENP-A containing nucleosome assembly (GO:0034080) | 3.08187216 |
| 75 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.06491113 |
| 76 | maturation of 5.8S rRNA (GO:0000460) | 3.06167626 |
| 77 | pseudouridine synthesis (GO:0001522) | 3.04848293 |
| 78 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 3.04273485 |
| 79 | behavioral response to nicotine (GO:0035095) | 3.04044862 |
| 80 | deoxyribose phosphate catabolic process (GO:0046386) | 3.02810810 |
| 81 | ATP biosynthetic process (GO:0006754) | 3.02264110 |
| 82 | DNA double-strand break processing (GO:0000729) | 3.00387388 |
| 83 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.98736236 |
| 84 | rRNA processing (GO:0006364) | 2.97009836 |
| 85 | tRNA processing (GO:0008033) | 2.95524654 |
| 86 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.93008912 |
| 87 | DNA replication checkpoint (GO:0000076) | 2.92748270 |
| 88 | rRNA metabolic process (GO:0016072) | 2.92029608 |
| 89 | cellular component biogenesis (GO:0044085) | 2.91791398 |
| 90 | adenosine metabolic process (GO:0046085) | 2.90989737 |
| 91 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.90697854 |
| 92 | iron-sulfur cluster assembly (GO:0016226) | 2.88731389 |
| 93 | metallo-sulfur cluster assembly (GO:0031163) | 2.88731389 |
| 94 | intracellular protein transmembrane import (GO:0044743) | 2.88116287 |
| 95 | GTP biosynthetic process (GO:0006183) | 2.87564636 |
| 96 | organelle disassembly (GO:1903008) | 2.87069115 |
| 97 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.87060071 |
| 98 | positive regulation of ligase activity (GO:0051351) | 2.86871006 |
| 99 | deoxyribose phosphate metabolic process (GO:0019692) | 2.86515418 |
| 100 | protein-cofactor linkage (GO:0018065) | 2.85605988 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.11526703 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.79858942 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.83826065 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.50819034 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.45275304 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.20542436 |
| 7 | VDR_23849224_ChIP-Seq_CD4+_Human | 3.04664663 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.00002099 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.96393925 |
| 10 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.93307659 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.82630885 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.64053453 |
| 13 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.56233348 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.54730491 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.48836512 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.42820207 |
| 17 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.35390998 |
| 18 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.28304869 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.20990876 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.14864077 |
| 21 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.14007240 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.10513432 |
| 23 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.07524458 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.94946985 |
| 25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.91886795 |
| 26 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.85200023 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.77334759 |
| 28 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.76210832 |
| 29 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.71821965 |
| 30 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.71394817 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.70365492 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.69508420 |
| 33 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.68618048 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.67538227 |
| 35 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65010555 |
| 36 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.62950760 |
| 37 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.60373707 |
| 38 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.60349034 |
| 39 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.56875228 |
| 40 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.54585096 |
| 41 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.49934465 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.49629928 |
| 43 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.47814435 |
| 44 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.46191439 |
| 45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.45631786 |
| 46 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.45271799 |
| 47 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.42749971 |
| 48 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.40537856 |
| 49 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.39621467 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.38463795 |
| 51 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.37114848 |
| 52 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.34461752 |
| 53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30294078 |
| 54 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.27456373 |
| 55 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.24454452 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.23350503 |
| 57 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.22750953 |
| 58 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.20474459 |
| 59 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20089518 |
| 60 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20089518 |
| 61 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.17056748 |
| 62 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15190019 |
| 63 | AR_20517297_ChIP-Seq_VCAP_Human | 1.13853770 |
| 64 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.13517310 |
| 65 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.12956613 |
| 66 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.12729932 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10536059 |
| 68 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.08299039 |
| 69 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.07915864 |
| 70 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07587532 |
| 71 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.03877777 |
| 72 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.02383026 |
| 73 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.02276473 |
| 74 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.02132980 |
| 75 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00985460 |
| 76 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.99648794 |
| 77 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.99644308 |
| 78 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99428234 |
| 79 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.98864594 |
| 80 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96982352 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96982352 |
| 82 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.96226330 |
| 83 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.95553896 |
| 84 | GATA3_26560356_Chip-Seq_TH2_Human | 0.94379887 |
| 85 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.94338350 |
| 86 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.94077829 |
| 87 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.93812669 |
| 88 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.93658356 |
| 89 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.92182566 |
| 90 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91533045 |
| 91 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.91396683 |
| 92 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.90879799 |
| 93 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90281730 |
| 94 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.90047360 |
| 95 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.89690236 |
| 96 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.89149344 |
| 97 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.88953568 |
| 98 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.88509338 |
| 99 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.88170458 |
| 100 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.87229452 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003806_abnormal_nucleotide_metabolis | 4.67804385 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 4.03995031 |
| 3 | MP0008058_abnormal_DNA_repair | 3.23828705 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.23483613 |
| 5 | MP0009379_abnormal_foot_pigmentation | 2.96741740 |
| 6 | MP0005671_abnormal_response_to | 2.79773269 |
| 7 | MP0005084_abnormal_gallbladder_morpholo | 2.70716333 |
| 8 | MP0000372_irregular_coat_pigmentation | 2.21266661 |
| 9 | MP0008872_abnormal_physiological_respon | 2.19403797 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.12890290 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.09267934 |
| 12 | MP0002102_abnormal_ear_morphology | 2.06901060 |
| 13 | MP0010094_abnormal_chromosome_stability | 1.89777860 |
| 14 | MP0004742_abnormal_vestibular_system | 1.83982710 |
| 15 | MP0001485_abnormal_pinna_reflex | 1.82649038 |
| 16 | MP0003786_premature_aging | 1.81802891 |
| 17 | MP0008877_abnormal_DNA_methylation | 1.80812322 |
| 18 | MP0004145_abnormal_muscle_electrophysio | 1.74791910 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.73244358 |
| 20 | MP0003186_abnormal_redox_activity | 1.66623825 |
| 21 | MP0002736_abnormal_nociception_after | 1.66382402 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.66127750 |
| 23 | MP0006072_abnormal_retinal_apoptosis | 1.63913207 |
| 24 | MP0001529_abnormal_vocalization | 1.57508144 |
| 25 | MP0001835_abnormal_antigen_presentation | 1.57404612 |
| 26 | MP0003646_muscle_fatigue | 1.56676525 |
| 27 | MP0004885_abnormal_endolymph | 1.54873009 |
| 28 | MP0006276_abnormal_autonomic_nervous | 1.53219345 |
| 29 | MP0008007_abnormal_cellular_replicative | 1.52538905 |
| 30 | MP0001986_abnormal_taste_sensitivity | 1.37642646 |
| 31 | MP0009785_altered_susceptibility_to | 1.37633171 |
| 32 | MP0004142_abnormal_muscle_tone | 1.37470993 |
| 33 | MP0003718_maternal_effect | 1.36001743 |
| 34 | MP0004957_abnormal_blastocyst_morpholog | 1.35197217 |
| 35 | MP0000685_abnormal_immune_system | 1.33015504 |
| 36 | MP0002006_tumorigenesis | 1.31812170 |
| 37 | MP0002733_abnormal_thermal_nociception | 1.31256565 |
| 38 | MP0005645_abnormal_hypothalamus_physiol | 1.29705841 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.26926312 |
| 40 | MP0004147_increased_porphyrin_level | 1.23348733 |
| 41 | MP0002160_abnormal_reproductive_system | 1.20781000 |
| 42 | MP0005551_abnormal_eye_electrophysiolog | 1.19889101 |
| 43 | MP0001293_anophthalmia | 1.19053183 |
| 44 | MP0005389_reproductive_system_phenotype | 1.18974268 |
| 45 | MP0001905_abnormal_dopamine_level | 1.18645972 |
| 46 | MP0006036_abnormal_mitochondrial_physio | 1.18615323 |
| 47 | MP0006035_abnormal_mitochondrial_morpho | 1.17487344 |
| 48 | MP0002277_abnormal_respiratory_mucosa | 1.15585582 |
| 49 | MP0003011_delayed_dark_adaptation | 1.15127459 |
| 50 | MP0005387_immune_system_phenotype | 1.14837692 |
| 51 | MP0001790_abnormal_immune_system | 1.14837692 |
| 52 | MP0005379_endocrine/exocrine_gland_phen | 1.14070474 |
| 53 | MP0003866_abnormal_defecation | 1.13167058 |
| 54 | MP0001764_abnormal_homeostasis | 1.12940239 |
| 55 | MP0005646_abnormal_pituitary_gland | 1.12547958 |
| 56 | MP0002638_abnormal_pupillary_reflex | 1.09044718 |
| 57 | MP0002234_abnormal_pharynx_morphology | 1.06898988 |
| 58 | MP0002166_altered_tumor_susceptibility | 1.05721797 |
| 59 | MP0002653_abnormal_ependyma_morphology | 1.05053480 |
| 60 | MP0010386_abnormal_urinary_bladder | 1.03668829 |
| 61 | MP0004043_abnormal_pH_regulation | 1.02861197 |
| 62 | MP0001970_abnormal_pain_threshold | 1.01854016 |
| 63 | MP0001800_abnormal_humoral_immune | 0.97542250 |
| 64 | MP0008775_abnormal_heart_ventricle | 0.94516799 |
| 65 | MP0001929_abnormal_gametogenesis | 0.93627814 |
| 66 | MP0001188_hyperpigmentation | 0.93387494 |
| 67 | MP0009745_abnormal_behavioral_response | 0.90967033 |
| 68 | MP0002938_white_spotting | 0.90955282 |
| 69 | MP0009333_abnormal_splenocyte_physiolog | 0.90712305 |
| 70 | MP0003936_abnormal_reproductive_system | 0.90559073 |
| 71 | MP0001919_abnormal_reproductive_system | 0.89943229 |
| 72 | MP0002210_abnormal_sex_determination | 0.88903876 |
| 73 | MP0003111_abnormal_nucleus_morphology | 0.88889550 |
| 74 | MP0008789_abnormal_olfactory_epithelium | 0.86932265 |
| 75 | MP0002095_abnormal_skin_pigmentation | 0.86491286 |
| 76 | MP0005636_abnormal_mineral_homeostasis | 0.86394647 |
| 77 | MP0003567_abnormal_fetal_cardiomyocyte | 0.86344098 |
| 78 | MP0004215_abnormal_myocardial_fiber | 0.86228972 |
| 79 | MP0000569_abnormal_digit_pigmentation | 0.85036407 |
| 80 | MP0003693_abnormal_embryo_hatching | 0.84991029 |
| 81 | MP0000427_abnormal_hair_cycle | 0.84184628 |
| 82 | MP0005174_abnormal_tail_pigmentation | 0.84085702 |
| 83 | MP0005253_abnormal_eye_physiology | 0.83745795 |
| 84 | MP0003878_abnormal_ear_physiology | 0.79537146 |
| 85 | MP0005377_hearing/vestibular/ear_phenot | 0.79537146 |
| 86 | MP0000631_abnormal_neuroendocrine_gland | 0.79356112 |
| 87 | MP0002163_abnormal_gland_morphology | 0.77972220 |
| 88 | MP0003137_abnormal_impulse_conducting | 0.77643941 |
| 89 | MP0003195_calcinosis | 0.77223533 |
| 90 | MP0008995_early_reproductive_senescence | 0.76085195 |
| 91 | MP0005410_abnormal_fertilization | 0.75630823 |
| 92 | MP0005394_taste/olfaction_phenotype | 0.74697604 |
| 93 | MP0005499_abnormal_olfactory_system | 0.74697604 |
| 94 | MP0002272_abnormal_nervous_system | 0.74469816 |
| 95 | MP0001145_abnormal_male_reproductive | 0.74425236 |
| 96 | MP0003252_abnormal_bile_duct | 0.72522123 |
| 97 | MP0000049_abnormal_middle_ear | 0.71958764 |
| 98 | MP0000613_abnormal_salivary_gland | 0.71832763 |
| 99 | MP0000653_abnormal_sex_gland | 0.71721461 |
| 100 | MP0009764_decreased_sensitivity_to | 0.69651846 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.02064290 |
| 2 | Acute encephalopathy (HP:0006846) | 4.56988390 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.49106107 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.38697136 |
| 5 | Hepatocellular necrosis (HP:0001404) | 4.32195521 |
| 6 | Increased CSF lactate (HP:0002490) | 4.14080693 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 4.13260178 |
| 8 | Progressive macrocephaly (HP:0004481) | 4.11827921 |
| 9 | Hepatic necrosis (HP:0002605) | 4.11349147 |
| 10 | Abnormality of alanine metabolism (HP:0010916) | 3.88869283 |
| 11 | Hyperalaninemia (HP:0003348) | 3.88869283 |
| 12 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.88869283 |
| 13 | Aplastic anemia (HP:0001915) | 3.41735475 |
| 14 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.38346291 |
| 15 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.38346291 |
| 16 | Congenital, generalized hypertrichosis (HP:0004540) | 3.35302510 |
| 17 | Pancreatic cysts (HP:0001737) | 3.29922782 |
| 18 | Cerebral edema (HP:0002181) | 3.16772122 |
| 19 | Increased serum lactate (HP:0002151) | 3.13143590 |
| 20 | Congenital stationary night blindness (HP:0007642) | 3.01793884 |
| 21 | Abnormality of midbrain morphology (HP:0002418) | 2.96567872 |
| 22 | Molar tooth sign on MRI (HP:0002419) | 2.96567872 |
| 23 | Pancreatic fibrosis (HP:0100732) | 2.95141398 |
| 24 | True hermaphroditism (HP:0010459) | 2.86219989 |
| 25 | Lactic acidosis (HP:0003128) | 2.81271961 |
| 26 | Increased hepatocellular lipid droplets (HP:0006565) | 2.76312921 |
| 27 | Reticulocytopenia (HP:0001896) | 2.76294235 |
| 28 | Hyperglycinemia (HP:0002154) | 2.74367330 |
| 29 | Optic disc pallor (HP:0000543) | 2.69419082 |
| 30 | Pendular nystagmus (HP:0012043) | 2.61944117 |
| 31 | Abnormality of the renal cortex (HP:0011035) | 2.59006322 |
| 32 | Type II lissencephaly (HP:0007260) | 2.58554878 |
| 33 | Dry hair (HP:0011359) | 2.57335523 |
| 34 | Nephronophthisis (HP:0000090) | 2.49956974 |
| 35 | Abnormality of serum amino acid levels (HP:0003112) | 2.49301381 |
| 36 | Pancytopenia (HP:0001876) | 2.48071686 |
| 37 | Methylmalonic aciduria (HP:0012120) | 2.43980247 |
| 38 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.42702243 |
| 39 | Type I transferrin isoform profile (HP:0003642) | 2.42476607 |
| 40 | Methylmalonic acidemia (HP:0002912) | 2.41856255 |
| 41 | Respiratory failure (HP:0002878) | 2.40235672 |
| 42 | Lipid accumulation in hepatocytes (HP:0006561) | 2.39989272 |
| 43 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.33846347 |
| 44 | Abnormal biliary tract physiology (HP:0012439) | 2.33585472 |
| 45 | Bile duct proliferation (HP:0001408) | 2.33585472 |
| 46 | Leukodystrophy (HP:0002415) | 2.32872089 |
| 47 | Lethargy (HP:0001254) | 2.31391631 |
| 48 | Colon cancer (HP:0003003) | 2.30758895 |
| 49 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.24418853 |
| 50 | Increased intramyocellular lipid droplets (HP:0012240) | 2.18267189 |
| 51 | Renal cortical cysts (HP:0000803) | 2.17856934 |
| 52 | Exercise intolerance (HP:0003546) | 2.15351549 |
| 53 | Abnormality of the renal medulla (HP:0100957) | 2.12216885 |
| 54 | Microvesicular hepatic steatosis (HP:0001414) | 2.12086482 |
| 55 | Abnormality of the axillary hair (HP:0100134) | 2.11127465 |
| 56 | Abnormality of secondary sexual hair (HP:0009888) | 2.11127465 |
| 57 | Macrocytic anemia (HP:0001972) | 2.10226768 |
| 58 | Delayed CNS myelination (HP:0002188) | 2.09591834 |
| 59 | Abnormal glycosylation (HP:0012345) | 2.05804543 |
| 60 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.05804543 |
| 61 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.05804543 |
| 62 | Abnormal protein glycosylation (HP:0012346) | 2.05804543 |
| 63 | Generalized aminoaciduria (HP:0002909) | 2.05312535 |
| 64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.04185788 |
| 65 | Panhypogammaglobulinemia (HP:0003139) | 2.01235325 |
| 66 | Asplenia (HP:0001746) | 2.00416062 |
| 67 | Absent thumb (HP:0009777) | 2.00299308 |
| 68 | Tubular atrophy (HP:0000092) | 1.99082151 |
| 69 | Hypomagnesemia (HP:0002917) | 1.98709630 |
| 70 | IgG deficiency (HP:0004315) | 1.97570476 |
| 71 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.97536362 |
| 72 | CNS demyelination (HP:0007305) | 1.97213174 |
| 73 | Renal Fanconi syndrome (HP:0001994) | 1.96859852 |
| 74 | Abolished electroretinogram (ERG) (HP:0000550) | 1.96458265 |
| 75 | Pallor (HP:0000980) | 1.91858756 |
| 76 | Supernumerary spleens (HP:0009799) | 1.91653683 |
| 77 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.91155689 |
| 78 | Sclerocornea (HP:0000647) | 1.89283249 |
| 79 | Dicarboxylic aciduria (HP:0003215) | 1.88535542 |
| 80 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.88535542 |
| 81 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.88329108 |
| 82 | Hypoproteinemia (HP:0003075) | 1.87219177 |
| 83 | Abnormality of magnesium homeostasis (HP:0004921) | 1.87091049 |
| 84 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.85215816 |
| 85 | Birth length less than 3rd percentile (HP:0003561) | 1.85173151 |
| 86 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.84680003 |
| 87 | Severe combined immunodeficiency (HP:0004430) | 1.84512564 |
| 88 | Male pseudohermaphroditism (HP:0000037) | 1.84163383 |
| 89 | Fair hair (HP:0002286) | 1.81416114 |
| 90 | Polyuria (HP:0000103) | 1.81250475 |
| 91 | Progressive microcephaly (HP:0000253) | 1.80334689 |
| 92 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.79833491 |
| 93 | Hypoplasia of the uterus (HP:0000013) | 1.79247057 |
| 94 | Abnormal drinking behavior (HP:0030082) | 1.78335901 |
| 95 | Polydipsia (HP:0001959) | 1.78335901 |
| 96 | Hypoplasia of the pons (HP:0012110) | 1.77812654 |
| 97 | Exertional dyspnea (HP:0002875) | 1.77695532 |
| 98 | Cystic liver disease (HP:0006706) | 1.77059122 |
| 99 | Constricted visual fields (HP:0001133) | 1.77034644 |
| 100 | Respiratory difficulties (HP:0002880) | 1.76478779 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.73606960 |
| 2 | TAOK3 | 3.67000050 |
| 3 | TLK1 | 3.43073173 |
| 4 | TRIM28 | 2.64145580 |
| 5 | WNK3 | 2.62313396 |
| 6 | NUAK1 | 2.55631825 |
| 7 | BUB1 | 2.48570007 |
| 8 | ZAK | 2.39790571 |
| 9 | VRK1 | 2.31470747 |
| 10 | TAF1 | 2.29208249 |
| 11 | MST4 | 2.28104238 |
| 12 | ADRBK2 | 2.26488133 |
| 13 | NEK1 | 2.13624982 |
| 14 | WNK4 | 1.92904471 |
| 15 | PDK2 | 1.90901680 |
| 16 | CDC7 | 1.74936459 |
| 17 | FRK | 1.70923556 |
| 18 | STK16 | 1.61469839 |
| 19 | GRK1 | 1.56307975 |
| 20 | MAP3K12 | 1.56007990 |
| 21 | TXK | 1.51249064 |
| 22 | PINK1 | 1.45846006 |
| 23 | SIK2 | 1.44514856 |
| 24 | PHKG1 | 1.32547390 |
| 25 | PHKG2 | 1.32547390 |
| 26 | EIF2AK3 | 1.23395124 |
| 27 | SCYL2 | 1.21082221 |
| 28 | EIF2AK1 | 1.17927578 |
| 29 | TEC | 1.11860037 |
| 30 | PLK3 | 1.08897033 |
| 31 | MAP4K2 | 1.08651323 |
| 32 | NEK2 | 1.07740328 |
| 33 | BCKDK | 1.07682487 |
| 34 | DAPK1 | 1.06723214 |
| 35 | KDR | 1.03821121 |
| 36 | SRPK1 | 1.02558987 |
| 37 | CAMKK2 | 1.02020396 |
| 38 | CSNK1G3 | 1.01183300 |
| 39 | BMPR1B | 0.99729970 |
| 40 | TSSK6 | 0.99383088 |
| 41 | MYLK | 0.99130442 |
| 42 | PASK | 0.95961041 |
| 43 | ATR | 0.95248711 |
| 44 | PLK1 | 0.91033187 |
| 45 | CDK8 | 0.90406193 |
| 46 | PLK4 | 0.88757730 |
| 47 | FLT3 | 0.88754239 |
| 48 | DYRK2 | 0.86066811 |
| 49 | CSNK1G1 | 0.84392660 |
| 50 | ITK | 0.84339284 |
| 51 | PBK | 0.84169581 |
| 52 | TTK | 0.82076448 |
| 53 | STK39 | 0.81530571 |
| 54 | CSNK1A1L | 0.76693131 |
| 55 | MAP4K1 | 0.75433212 |
| 56 | AURKA | 0.74795950 |
| 57 | TNIK | 0.74214354 |
| 58 | NME1 | 0.73499977 |
| 59 | CSNK1G2 | 0.72504392 |
| 60 | DAPK3 | 0.72479491 |
| 61 | FES | 0.69010832 |
| 62 | ERBB3 | 0.68599200 |
| 63 | EIF2AK2 | 0.68135572 |
| 64 | PLK2 | 0.66421229 |
| 65 | TIE1 | 0.66085408 |
| 66 | AURKB | 0.62947414 |
| 67 | ADRBK1 | 0.61467386 |
| 68 | PRKCQ | 0.61218633 |
| 69 | SYK | 0.60300296 |
| 70 | PTK2B | 0.59283958 |
| 71 | BCR | 0.59185350 |
| 72 | INSRR | 0.59083241 |
| 73 | MKNK1 | 0.58321787 |
| 74 | OXSR1 | 0.56512389 |
| 75 | RPS6KA5 | 0.56325146 |
| 76 | GRK7 | 0.54073900 |
| 77 | IKBKB | 0.53843373 |
| 78 | CSNK2A1 | 0.51386332 |
| 79 | CSF1R | 0.51064972 |
| 80 | PRKCG | 0.50192384 |
| 81 | CSNK2A2 | 0.49657485 |
| 82 | STK4 | 0.47673484 |
| 83 | GRK5 | 0.47632588 |
| 84 | LYN | 0.47239902 |
| 85 | PIK3CG | 0.46088253 |
| 86 | MKNK2 | 0.45458410 |
| 87 | DAPK2 | 0.43073266 |
| 88 | PIK3CA | 0.42985637 |
| 89 | STK3 | 0.41625469 |
| 90 | CSNK1A1 | 0.40452965 |
| 91 | STK38L | 0.40302119 |
| 92 | MAPK13 | 0.39629215 |
| 93 | CCNB1 | 0.39545874 |
| 94 | BRSK1 | 0.39410937 |
| 95 | CHEK2 | 0.39345892 |
| 96 | STK24 | 0.38299900 |
| 97 | ATM | 0.38297897 |
| 98 | TGFBR1 | 0.37687947 |
| 99 | WEE1 | 0.36629586 |
| 100 | PRKCA | 0.36302440 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.13204339 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.85981757 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.57973833 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.02444374 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.50374057 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.35591967 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.29575305 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.25332289 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.23295413 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.21056780 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.10252881 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 2.06527417 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.01144142 |
| 14 | Base excision repair_Homo sapiens_hsa03410 | 1.97985109 |
| 15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.95607950 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.89517830 |
| 17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.89242340 |
| 18 | Allograft rejection_Homo sapiens_hsa05330 | 1.82408773 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.79754727 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.75878259 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.67970554 |
| 22 | DNA replication_Homo sapiens_hsa03030 | 1.65118827 |
| 23 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.62143385 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.59711417 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.55352325 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.55122891 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.53288259 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.53146999 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.52600892 |
| 30 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.42713239 |
| 31 | RNA transport_Homo sapiens_hsa03013 | 1.35623807 |
| 32 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.33719724 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.30088623 |
| 34 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27997907 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.26097879 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.24199625 |
| 37 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.21069925 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.19848804 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.18521265 |
| 40 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.17066965 |
| 41 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.15470329 |
| 42 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.12946857 |
| 43 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.10269014 |
| 44 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.08760042 |
| 45 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.08464502 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 1.07829317 |
| 47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.07738781 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 1.01116950 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.96678477 |
| 50 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.93212851 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.91171051 |
| 52 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.89600681 |
| 53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.88559135 |
| 54 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.87025164 |
| 55 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.86960026 |
| 56 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.85899279 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.81146694 |
| 58 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.81027807 |
| 59 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.76060950 |
| 60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.73085879 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.70146889 |
| 62 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.69542493 |
| 63 | Sulfur relay system_Homo sapiens_hsa04122 | 0.69380963 |
| 64 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.66112761 |
| 65 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.62430470 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.61340328 |
| 67 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.61061528 |
| 68 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59935882 |
| 69 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.59536368 |
| 70 | Viral myocarditis_Homo sapiens_hsa05416 | 0.56076897 |
| 71 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.54596822 |
| 72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52606911 |
| 73 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.51937064 |
| 74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.50980448 |
| 75 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.50187662 |
| 76 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48289496 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47960922 |
| 78 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.47710006 |
| 79 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47453604 |
| 80 | Retinol metabolism_Homo sapiens_hsa00830 | 0.43291736 |
| 81 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.42833362 |
| 82 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.42383094 |
| 83 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.42213851 |
| 84 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.38366052 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38143486 |
| 86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.36584617 |
| 87 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.35565534 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35032607 |
| 89 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.34057817 |
| 90 | Cell cycle_Homo sapiens_hsa04110 | 0.33164680 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.31273628 |
| 92 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29822805 |
| 93 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.27767060 |
| 94 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.27494069 |
| 95 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27047967 |
| 96 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.26656543 |
| 97 | Carbon metabolism_Homo sapiens_hsa01200 | 0.26309206 |
| 98 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.26272428 |
| 99 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.24899954 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.24727519 |

