

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 8.65917761 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 6.60700988 |
| 3 | viral transcription (GO:0019083) | 6.52517994 |
| 4 | translational termination (GO:0006415) | 6.27058296 |
| 5 | DNA deamination (GO:0045006) | 5.98798923 |
| 6 | maturation of SSU-rRNA (GO:0030490) | 5.90846743 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.70166663 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 5.64236390 |
| 9 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.62583286 |
| 10 | protein targeting to ER (GO:0045047) | 5.59410484 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.54698521 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 5.54698521 |
| 13 | translational elongation (GO:0006414) | 5.54105952 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.34949788 |
| 15 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.27048356 |
| 16 | protein localization to endoplasmic reticulum (GO:0070972) | 5.25084299 |
| 17 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.16430175 |
| 18 | protein neddylation (GO:0045116) | 4.82277780 |
| 19 | cellular protein complex disassembly (GO:0043624) | 4.74498914 |
| 20 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.65515840 |
| 21 | viral life cycle (GO:0019058) | 4.65393453 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.57074719 |
| 23 | translational initiation (GO:0006413) | 4.52624601 |
| 24 | chaperone-mediated protein transport (GO:0072321) | 4.44608671 |
| 25 | translation (GO:0006412) | 4.28861192 |
| 26 | respiratory electron transport chain (GO:0022904) | 4.15335097 |
| 27 | behavioral response to nicotine (GO:0035095) | 4.13834370 |
| 28 | protein complex biogenesis (GO:0070271) | 4.13463106 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.11204189 |
| 30 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.11204189 |
| 31 | electron transport chain (GO:0022900) | 4.10724831 |
| 32 | protein complex disassembly (GO:0043241) | 3.96120493 |
| 33 | ncRNA 3-end processing (GO:0043628) | 3.90928307 |
| 34 | ribosomal large subunit biogenesis (GO:0042273) | 3.90124160 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.81746774 |
| 36 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.78257315 |
| 37 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.78201267 |
| 38 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.78201267 |
| 39 | NADH dehydrogenase complex assembly (GO:0010257) | 3.78201267 |
| 40 | macromolecular complex disassembly (GO:0032984) | 3.75743784 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.74704956 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.74300955 |
| 43 | protein targeting to membrane (GO:0006612) | 3.67492696 |
| 44 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.65924009 |
| 45 | cytidine metabolic process (GO:0046087) | 3.64437931 |
| 46 | cytidine catabolic process (GO:0006216) | 3.64437931 |
| 47 | cytidine deamination (GO:0009972) | 3.64437931 |
| 48 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.59934216 |
| 49 | cellular component biogenesis (GO:0044085) | 3.58112178 |
| 50 | GTP biosynthetic process (GO:0006183) | 3.43471746 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.43183463 |
| 52 | mRNA catabolic process (GO:0006402) | 3.38588404 |
| 53 | cytochrome complex assembly (GO:0017004) | 3.29207536 |
| 54 | response to pheromone (GO:0019236) | 3.22539499 |
| 55 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.21149685 |
| 56 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.20219446 |
| 57 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.14747050 |
| 58 | termination of RNA polymerase III transcription (GO:0006386) | 3.14747050 |
| 59 | ATP biosynthetic process (GO:0006754) | 3.14100613 |
| 60 | RNA catabolic process (GO:0006401) | 3.13098458 |
| 61 | rRNA modification (GO:0000154) | 3.08232085 |
| 62 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.05470874 |
| 63 | rRNA processing (GO:0006364) | 3.03898132 |
| 64 | pseudouridine synthesis (GO:0001522) | 3.01268264 |
| 65 | rRNA metabolic process (GO:0016072) | 2.99532051 |
| 66 | sequestering of actin monomers (GO:0042989) | 2.98526422 |
| 67 | protein-cofactor linkage (GO:0018065) | 2.97625541 |
| 68 | branched-chain amino acid catabolic process (GO:0009083) | 2.96389130 |
| 69 | UTP biosynthetic process (GO:0006228) | 2.93415282 |
| 70 | hydrogen ion transmembrane transport (GO:1902600) | 2.91167601 |
| 71 | proteasome assembly (GO:0043248) | 2.87932146 |
| 72 | chromatin remodeling at centromere (GO:0031055) | 2.86867282 |
| 73 | DNA damage response, detection of DNA damage (GO:0042769) | 2.84941045 |
| 74 | regulation of mitochondrial translation (GO:0070129) | 2.84717522 |
| 75 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.84333069 |
| 76 | mannosylation (GO:0097502) | 2.82393813 |
| 77 | ubiquinone biosynthetic process (GO:0006744) | 2.80267684 |
| 78 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.78279672 |
| 79 | signal peptide processing (GO:0006465) | 2.71197799 |
| 80 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.70854066 |
| 81 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 2.70450804 |
| 82 | cell proliferation in forebrain (GO:0021846) | 2.68392746 |
| 83 | positive regulation of respiratory burst (GO:0060267) | 2.66405571 |
| 84 | UTP metabolic process (GO:0046051) | 2.64679068 |
| 85 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.61567691 |
| 86 | ribosome biogenesis (GO:0042254) | 2.57977880 |
| 87 | tRNA processing (GO:0008033) | 2.57490032 |
| 88 | proton transport (GO:0015992) | 2.56786809 |
| 89 | negative regulation of ligase activity (GO:0051352) | 2.56050499 |
| 90 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.56050499 |
| 91 | axoneme assembly (GO:0035082) | 2.54494816 |
| 92 | CENP-A containing nucleosome assembly (GO:0034080) | 2.54360453 |
| 93 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.53857404 |
| 94 | protein targeting (GO:0006605) | 2.53602266 |
| 95 | protein targeting to mitochondrion (GO:0006626) | 2.53335435 |
| 96 | ubiquinone metabolic process (GO:0006743) | 2.52890198 |
| 97 | intracellular protein transmembrane import (GO:0044743) | 2.52721050 |
| 98 | CTP metabolic process (GO:0046036) | 2.52593581 |
| 99 | CTP biosynthetic process (GO:0006241) | 2.52593581 |
| 100 | platelet dense granule organization (GO:0060155) | 2.51210052 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.87426339 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.47254868 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.16271856 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.44374660 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.26795518 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.12077505 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.95853628 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.93450530 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.90533635 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.65887310 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.48904649 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.45891813 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.30072567 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.29788059 |
| 15 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.22566043 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.19148507 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.16640964 |
| 18 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.15177879 |
| 19 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.14235965 |
| 20 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.10119326 |
| 21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.94600472 |
| 22 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.92249346 |
| 23 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.86965048 |
| 24 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.84459944 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.82256926 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.80199544 |
| 27 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.79475531 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.71858892 |
| 29 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.67865449 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.67295472 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.64881094 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.50433565 |
| 33 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.49392329 |
| 34 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.49207445 |
| 35 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.48071815 |
| 36 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.47156529 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.43164500 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43027679 |
| 39 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.40741198 |
| 40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.38647679 |
| 41 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.37835962 |
| 42 | FUS_26573619_Chip-Seq_HEK293_Human | 1.35044484 |
| 43 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.34510124 |
| 44 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.33854469 |
| 45 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.33050607 |
| 46 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.31627586 |
| 47 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.31622406 |
| 48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.31273233 |
| 49 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.28107328 |
| 50 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.26496541 |
| 51 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.26303851 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.23288656 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.23288656 |
| 54 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.23204744 |
| 55 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.22259433 |
| 56 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18750671 |
| 57 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.17090778 |
| 58 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.16345531 |
| 59 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.15744748 |
| 60 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.14542599 |
| 61 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.14198840 |
| 62 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.12569091 |
| 63 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.11740814 |
| 64 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.11584378 |
| 65 | P300_19829295_ChIP-Seq_ESCs_Human | 1.11375383 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.06840826 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.06840826 |
| 68 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.06242978 |
| 69 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06129747 |
| 70 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.04357702 |
| 71 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.03040174 |
| 72 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.02850712 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01491755 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.00108499 |
| 75 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99370686 |
| 76 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99293901 |
| 77 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.99275311 |
| 78 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.98851736 |
| 79 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.97287504 |
| 80 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.97285242 |
| 81 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.96850970 |
| 82 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.95819922 |
| 83 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.95156610 |
| 84 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91207097 |
| 85 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.91148220 |
| 86 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.91148220 |
| 87 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.90919433 |
| 88 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.90624708 |
| 89 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.89919786 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.89692748 |
| 91 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88648768 |
| 92 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.88186636 |
| 93 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.86930836 |
| 94 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.85345765 |
| 95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.85037084 |
| 96 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.84401598 |
| 97 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.81435575 |
| 98 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.81213575 |
| 99 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.80955829 |
| 100 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.80465744 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.97326116 |
| 2 | MP0006292_abnormal_olfactory_placode | 5.53578158 |
| 3 | MP0008877_abnormal_DNA_methylation | 3.34757958 |
| 4 | MP0003646_muscle_fatigue | 2.60336846 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 2.58323655 |
| 6 | MP0003136_yellow_coat_color | 2.29055206 |
| 7 | MP0008789_abnormal_olfactory_epithelium | 2.25514850 |
| 8 | MP0001293_anophthalmia | 2.12295153 |
| 9 | MP0002736_abnormal_nociception_after | 2.09138309 |
| 10 | MP0002653_abnormal_ependyma_morphology | 2.06193766 |
| 11 | MP0001348_abnormal_lacrimal_gland | 2.04597067 |
| 12 | MP0002163_abnormal_gland_morphology | 2.03398227 |
| 13 | MP0003787_abnormal_imprinting | 1.85894699 |
| 14 | MP0002138_abnormal_hepatobiliary_system | 1.84656919 |
| 15 | MP0005499_abnormal_olfactory_system | 1.82902362 |
| 16 | MP0005394_taste/olfaction_phenotype | 1.82902362 |
| 17 | MP0001485_abnormal_pinna_reflex | 1.82759797 |
| 18 | MP0008872_abnormal_physiological_respon | 1.80183949 |
| 19 | MP0002638_abnormal_pupillary_reflex | 1.80008252 |
| 20 | MP0004142_abnormal_muscle_tone | 1.76098981 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.73689864 |
| 22 | MP0005646_abnormal_pituitary_gland | 1.70292846 |
| 23 | MP0004147_increased_porphyrin_level | 1.69408162 |
| 24 | MP0001968_abnormal_touch/_nociception | 1.65464677 |
| 25 | MP0002102_abnormal_ear_morphology | 1.62748733 |
| 26 | MP0000049_abnormal_middle_ear | 1.62508412 |
| 27 | MP0003122_maternal_imprinting | 1.61697073 |
| 28 | MP0003878_abnormal_ear_physiology | 1.60004058 |
| 29 | MP0005377_hearing/vestibular/ear_phenot | 1.60004058 |
| 30 | MP0006072_abnormal_retinal_apoptosis | 1.58457103 |
| 31 | MP0002277_abnormal_respiratory_mucosa | 1.55400065 |
| 32 | MP0005551_abnormal_eye_electrophysiolog | 1.52084540 |
| 33 | MP0005379_endocrine/exocrine_gland_phen | 1.51975531 |
| 34 | MP0002938_white_spotting | 1.51110297 |
| 35 | MP0001188_hyperpigmentation | 1.51094794 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.50781469 |
| 37 | MP0005671_abnormal_response_to | 1.49529558 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.43602963 |
| 39 | MP0000631_abnormal_neuroendocrine_gland | 1.42834957 |
| 40 | MP0008058_abnormal_DNA_repair | 1.36434136 |
| 41 | MP0001529_abnormal_vocalization | 1.29206971 |
| 42 | MP0002272_abnormal_nervous_system | 1.27321589 |
| 43 | MP0004742_abnormal_vestibular_system | 1.25502285 |
| 44 | MP0003186_abnormal_redox_activity | 1.22787457 |
| 45 | MP0002095_abnormal_skin_pigmentation | 1.19172429 |
| 46 | MP0003567_abnormal_fetal_cardiomyocyte | 1.13247765 |
| 47 | MP0005389_reproductive_system_phenotype | 1.12256520 |
| 48 | MP0005645_abnormal_hypothalamus_physiol | 1.11625346 |
| 49 | MP0001984_abnormal_olfaction | 1.11119423 |
| 50 | MP0001905_abnormal_dopamine_level | 1.10889480 |
| 51 | MP0003880_abnormal_central_pattern | 1.10420451 |
| 52 | MP0003121_genomic_imprinting | 1.08860365 |
| 53 | MP0004885_abnormal_endolymph | 1.07553145 |
| 54 | MP0002160_abnormal_reproductive_system | 1.06869876 |
| 55 | MP0003786_premature_aging | 1.06606933 |
| 56 | MP0005174_abnormal_tail_pigmentation | 1.05959528 |
| 57 | MP0008875_abnormal_xenobiotic_pharmacok | 1.04934236 |
| 58 | MP0003123_paternal_imprinting | 1.03936858 |
| 59 | MP0003937_abnormal_limbs/digits/tail_de | 1.02408127 |
| 60 | MP0001919_abnormal_reproductive_system | 1.02402677 |
| 61 | MP0008995_early_reproductive_senescence | 1.01855855 |
| 62 | MP0004133_heterotaxia | 1.00034365 |
| 63 | MP0006276_abnormal_autonomic_nervous | 0.98993861 |
| 64 | MP0003693_abnormal_embryo_hatching | 0.93918047 |
| 65 | MP0009745_abnormal_behavioral_response | 0.92907709 |
| 66 | MP0002557_abnormal_social/conspecific_i | 0.92777162 |
| 67 | MP0005253_abnormal_eye_physiology | 0.92031645 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.90400278 |
| 69 | MP0002233_abnormal_nose_morphology | 0.89505652 |
| 70 | MP0001764_abnormal_homeostasis | 0.87386419 |
| 71 | MP0001986_abnormal_taste_sensitivity | 0.86834175 |
| 72 | MP0002876_abnormal_thyroid_physiology | 0.86651532 |
| 73 | MP0003718_maternal_effect | 0.86503863 |
| 74 | MP0005636_abnormal_mineral_homeostasis | 0.84718179 |
| 75 | MP0005195_abnormal_posterior_eye | 0.83804791 |
| 76 | MP0003195_calcinosis | 0.83350941 |
| 77 | MP0002210_abnormal_sex_determination | 0.83318353 |
| 78 | MP0006036_abnormal_mitochondrial_physio | 0.82256219 |
| 79 | MP0002752_abnormal_somatic_nervous | 0.81493313 |
| 80 | MP0003119_abnormal_digestive_system | 0.80526910 |
| 81 | MP0000026_abnormal_inner_ear | 0.80344579 |
| 82 | MP0005075_abnormal_melanosome_morpholog | 0.78956554 |
| 83 | MP0001440_abnormal_grooming_behavior | 0.76800136 |
| 84 | MP0001286_abnormal_eye_development | 0.76436440 |
| 85 | MP0003938_abnormal_ear_development | 0.75733375 |
| 86 | MP0001970_abnormal_pain_threshold | 0.74713665 |
| 87 | MP0004957_abnormal_blastocyst_morpholog | 0.74638390 |
| 88 | MP0002822_catalepsy | 0.73904554 |
| 89 | MP0001486_abnormal_startle_reflex | 0.72553939 |
| 90 | MP0001963_abnormal_hearing_physiology | 0.70784312 |
| 91 | MP0009046_muscle_twitch | 0.69445782 |
| 92 | MP0003011_delayed_dark_adaptation | 0.68797147 |
| 93 | MP0003806_abnormal_nucleotide_metabolis | 0.68173429 |
| 94 | MP0000653_abnormal_sex_gland | 0.67245505 |
| 95 | MP0001929_abnormal_gametogenesis | 0.67178817 |
| 96 | MP0003936_abnormal_reproductive_system | 0.65686869 |
| 97 | MP0009333_abnormal_splenocyte_physiolog | 0.64271935 |
| 98 | MP0001145_abnormal_male_reproductive | 0.64043355 |
| 99 | MP0002928_abnormal_bile_duct | 0.63751193 |
| 100 | MP0008775_abnormal_heart_ventricle | 0.63310871 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.82779034 |
| 2 | Reticulocytopenia (HP:0001896) | 4.52616224 |
| 3 | Acute encephalopathy (HP:0006846) | 4.30505986 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.25172994 |
| 5 | Mitochondrial inheritance (HP:0001427) | 4.13600275 |
| 6 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.99814271 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.92103096 |
| 8 | Increased CSF lactate (HP:0002490) | 3.77771640 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.55502031 |
| 10 | Pancreatic cysts (HP:0001737) | 3.37327744 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.35809917 |
| 12 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.27173064 |
| 13 | Cerebral edema (HP:0002181) | 3.24856460 |
| 14 | Hepatocellular necrosis (HP:0001404) | 3.24254913 |
| 15 | Colon cancer (HP:0003003) | 3.22144591 |
| 16 | Lipid accumulation in hepatocytes (HP:0006561) | 3.19412190 |
| 17 | 3-Methylglutaconic aciduria (HP:0003535) | 3.15354096 |
| 18 | Macrocytic anemia (HP:0001972) | 3.14330725 |
| 19 | Septo-optic dysplasia (HP:0100842) | 3.08945837 |
| 20 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.08729190 |
| 21 | True hermaphroditism (HP:0010459) | 3.02072515 |
| 22 | Abnormality of midbrain morphology (HP:0002418) | 2.98851597 |
| 23 | Molar tooth sign on MRI (HP:0002419) | 2.98851597 |
| 24 | Hepatic necrosis (HP:0002605) | 2.90772748 |
| 25 | Optic disc pallor (HP:0000543) | 2.90098435 |
| 26 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.88882046 |
| 27 | Renal Fanconi syndrome (HP:0001994) | 2.88642856 |
| 28 | Asplenia (HP:0001746) | 2.76108821 |
| 29 | Pendular nystagmus (HP:0012043) | 2.73131570 |
| 30 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.72066145 |
| 31 | Increased serum lactate (HP:0002151) | 2.61812723 |
| 32 | Hyperglycinemia (HP:0002154) | 2.59710924 |
| 33 | Sclerocornea (HP:0000647) | 2.57525113 |
| 34 | Aplastic anemia (HP:0001915) | 2.51407935 |
| 35 | Pallor (HP:0000980) | 2.51005768 |
| 36 | Nephronophthisis (HP:0000090) | 2.49656961 |
| 37 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.48290894 |
| 38 | Increased intramyocellular lipid droplets (HP:0012240) | 2.46086047 |
| 39 | Lactic acidosis (HP:0003128) | 2.44169784 |
| 40 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.43341312 |
| 41 | Abnormality of alanine metabolism (HP:0010916) | 2.43341312 |
| 42 | Hyperalaninemia (HP:0003348) | 2.43341312 |
| 43 | Abnormal biliary tract physiology (HP:0012439) | 2.35168231 |
| 44 | Bile duct proliferation (HP:0001408) | 2.35168231 |
| 45 | Abnormal number of erythroid precursors (HP:0012131) | 2.29372396 |
| 46 | Lethargy (HP:0001254) | 2.28825892 |
| 47 | Congenital stationary night blindness (HP:0007642) | 2.28254098 |
| 48 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.26968594 |
| 49 | Attenuation of retinal blood vessels (HP:0007843) | 2.26112687 |
| 50 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.25033105 |
| 51 | Anencephaly (HP:0002323) | 2.23201045 |
| 52 | Leukodystrophy (HP:0002415) | 2.23148565 |
| 53 | Abolished electroretinogram (ERG) (HP:0000550) | 2.22576118 |
| 54 | Abnormal ciliary motility (HP:0012262) | 2.19945324 |
| 55 | Medial flaring of the eyebrow (HP:0010747) | 2.15967082 |
| 56 | Absent thumb (HP:0009777) | 2.13628240 |
| 57 | Exertional dyspnea (HP:0002875) | 2.07215997 |
| 58 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.05999916 |
| 59 | Respiratory failure (HP:0002878) | 2.02904523 |
| 60 | Methylmalonic aciduria (HP:0012120) | 2.02402242 |
| 61 | Respiratory difficulties (HP:0002880) | 2.01225662 |
| 62 | Exercise intolerance (HP:0003546) | 2.00871430 |
| 63 | Constricted visual fields (HP:0001133) | 2.00648711 |
| 64 | Rib fusion (HP:0000902) | 2.00577364 |
| 65 | Cystic liver disease (HP:0006706) | 1.98837748 |
| 66 | Abnormality of the renal medulla (HP:0100957) | 1.98690578 |
| 67 | Abnormality of urine glucose concentration (HP:0011016) | 1.97641362 |
| 68 | Glycosuria (HP:0003076) | 1.97641362 |
| 69 | Postaxial foot polydactyly (HP:0001830) | 1.97625124 |
| 70 | Abnormality of the labia minora (HP:0012880) | 1.95785316 |
| 71 | Decreased central vision (HP:0007663) | 1.95725430 |
| 72 | Methylmalonic acidemia (HP:0002912) | 1.95673354 |
| 73 | Optic nerve hypoplasia (HP:0000609) | 1.95456886 |
| 74 | Increased muscle lipid content (HP:0009058) | 1.95024149 |
| 75 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.93448650 |
| 76 | Hypoplasia of the uterus (HP:0000013) | 1.93137348 |
| 77 | Pancytopenia (HP:0001876) | 1.91997763 |
| 78 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.91480015 |
| 79 | Abnormality of serum amino acid levels (HP:0003112) | 1.90312575 |
| 80 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.88318487 |
| 81 | Absent septum pellucidum (HP:0001331) | 1.88261055 |
| 82 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.86984937 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.86854460 |
| 84 | Abnormality of the renal cortex (HP:0011035) | 1.85314328 |
| 85 | Stenosis of the external auditory canal (HP:0000402) | 1.84601437 |
| 86 | Hyperphosphaturia (HP:0003109) | 1.84368131 |
| 87 | Congenital, generalized hypertrichosis (HP:0004540) | 1.83814740 |
| 88 | Supernumerary spleens (HP:0009799) | 1.83300749 |
| 89 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.83275964 |
| 90 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.82688136 |
| 91 | Absent/shortened dynein arms (HP:0200106) | 1.82688136 |
| 92 | Abnormal drinking behavior (HP:0030082) | 1.82148032 |
| 93 | Polydipsia (HP:0001959) | 1.82148032 |
| 94 | Type II lissencephaly (HP:0007260) | 1.81406387 |
| 95 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.80970846 |
| 96 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.80459376 |
| 97 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.80459376 |
| 98 | Maternal diabetes (HP:0009800) | 1.79124163 |
| 99 | Male pseudohermaphroditism (HP:0000037) | 1.78453564 |
| 100 | Ketosis (HP:0001946) | 1.77628345 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 3.44141076 |
| 2 | STK16 | 3.00824942 |
| 3 | BCKDK | 2.97211215 |
| 4 | WNK4 | 2.67518135 |
| 5 | NUAK1 | 2.40546793 |
| 6 | WNK3 | 2.38434008 |
| 7 | MAP4K2 | 2.26899700 |
| 8 | VRK2 | 2.25260057 |
| 9 | ADRBK2 | 2.10269652 |
| 10 | KDR | 2.01000656 |
| 11 | TNIK | 1.95201635 |
| 12 | CDK19 | 1.94945937 |
| 13 | TLK1 | 1.91914638 |
| 14 | DYRK2 | 1.88273675 |
| 15 | BUB1 | 1.85712021 |
| 16 | TXK | 1.83348182 |
| 17 | FRK | 1.79334810 |
| 18 | GRK1 | 1.77353458 |
| 19 | BMPR1B | 1.70059347 |
| 20 | PBK | 1.60924013 |
| 21 | TRIM28 | 1.60691710 |
| 22 | VRK1 | 1.56933559 |
| 23 | CDC7 | 1.55191123 |
| 24 | LIMK1 | 1.48787712 |
| 25 | CASK | 1.43832322 |
| 26 | MKNK2 | 1.43247691 |
| 27 | TIE1 | 1.33468781 |
| 28 | INSRR | 1.29344566 |
| 29 | PINK1 | 1.25976566 |
| 30 | TESK2 | 1.25586928 |
| 31 | MAP3K12 | 1.24882314 |
| 32 | PASK | 1.23156695 |
| 33 | MAP4K1 | 1.23092952 |
| 34 | NME2 | 1.20538002 |
| 35 | PRKCQ | 1.17829627 |
| 36 | MKNK1 | 1.12014538 |
| 37 | PLK4 | 1.11917159 |
| 38 | STK39 | 1.10399211 |
| 39 | PLK3 | 1.01379368 |
| 40 | MAP3K4 | 0.98452460 |
| 41 | MAP2K7 | 0.98201816 |
| 42 | LRRK2 | 0.97618218 |
| 43 | SRPK1 | 0.92670817 |
| 44 | ITK | 0.91435600 |
| 45 | TAOK3 | 0.88476693 |
| 46 | PRKCG | 0.86314677 |
| 47 | PLK1 | 0.85999571 |
| 48 | MST4 | 0.85613884 |
| 49 | BRSK2 | 0.85008707 |
| 50 | NME1 | 0.82691749 |
| 51 | TGFBR1 | 0.81966204 |
| 52 | ACVR1B | 0.79546348 |
| 53 | PDK2 | 0.79512534 |
| 54 | ADRBK1 | 0.78719374 |
| 55 | PIK3CA | 0.78532555 |
| 56 | WEE1 | 0.77218454 |
| 57 | NEK1 | 0.76788775 |
| 58 | MAPK13 | 0.74497256 |
| 59 | CAMK1 | 0.73289481 |
| 60 | TEC | 0.73155957 |
| 61 | EIF2AK3 | 0.72061902 |
| 62 | RPS6KA5 | 0.71203293 |
| 63 | AURKA | 0.69209886 |
| 64 | OXSR1 | 0.67450505 |
| 65 | TAF1 | 0.67109247 |
| 66 | CSNK2A2 | 0.66953397 |
| 67 | MAP3K11 | 0.65549426 |
| 68 | BRSK1 | 0.63862890 |
| 69 | EIF2AK1 | 0.63818012 |
| 70 | PLK2 | 0.62647800 |
| 71 | MAP3K9 | 0.61741306 |
| 72 | PRKD3 | 0.61454645 |
| 73 | MINK1 | 0.60275657 |
| 74 | ATR | 0.58255068 |
| 75 | MAP2K6 | 0.57455764 |
| 76 | AURKB | 0.56467314 |
| 77 | ABL2 | 0.55740015 |
| 78 | PRKACA | 0.54373806 |
| 79 | CSNK2A1 | 0.52337737 |
| 80 | IKBKB | 0.50086325 |
| 81 | PRKCI | 0.49093523 |
| 82 | CAMKK2 | 0.48753700 |
| 83 | CHEK2 | 0.46983363 |
| 84 | TSSK6 | 0.46411684 |
| 85 | CSNK1E | 0.44329199 |
| 86 | PRKCA | 0.41838114 |
| 87 | MYLK | 0.41751595 |
| 88 | OBSCN | 0.41373341 |
| 89 | CSNK1G1 | 0.39147570 |
| 90 | ERBB4 | 0.37365939 |
| 91 | CAMK2A | 0.37337437 |
| 92 | PIK3CG | 0.36414816 |
| 93 | GRK7 | 0.36059031 |
| 94 | PIM2 | 0.35863178 |
| 95 | PRKCE | 0.34031618 |
| 96 | BTK | 0.33751083 |
| 97 | CSNK1A1 | 0.33119359 |
| 98 | DAPK3 | 0.32767739 |
| 99 | EPHA4 | 0.31713095 |
| 100 | CSNK1G2 | 0.30509786 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.63613556 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.10161175 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.59063865 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.43385002 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.08474635 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.90963977 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.41563619 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.34780372 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.26702613 |
| 10 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.11683783 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.10446871 |
| 12 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.05394147 |
| 13 | RNA degradation_Homo sapiens_hsa03018 | 1.90945627 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.82742879 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.73196663 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.61744161 |
| 17 | Homologous recombination_Homo sapiens_hsa03440 | 1.57964657 |
| 18 | Mismatch repair_Homo sapiens_hsa03430 | 1.56173824 |
| 19 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.55718465 |
| 20 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.53449813 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.41895413 |
| 22 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.41183434 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.33492905 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.28621414 |
| 25 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.27088214 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.24956543 |
| 27 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.23666295 |
| 28 | Peroxisome_Homo sapiens_hsa04146 | 1.21156097 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.20397501 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.16412036 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.15058066 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.14782730 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.13428089 |
| 34 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.11861036 |
| 35 | RNA transport_Homo sapiens_hsa03013 | 1.11284661 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.10866260 |
| 37 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.10392809 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 1.08070600 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.06837092 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.06422694 |
| 41 | Sulfur relay system_Homo sapiens_hsa04122 | 1.03503228 |
| 42 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.02636192 |
| 43 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.01858670 |
| 44 | Allograft rejection_Homo sapiens_hsa05330 | 1.01291479 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.98719675 |
| 46 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.97421793 |
| 47 | Asthma_Homo sapiens_hsa05310 | 0.92898634 |
| 48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.91837892 |
| 49 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.87671966 |
| 50 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.83858784 |
| 51 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82528521 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.82421377 |
| 53 | Nicotine addiction_Homo sapiens_hsa05033 | 0.81860083 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.79990681 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.78061461 |
| 56 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.76440919 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.75401895 |
| 58 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.75174052 |
| 59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.73279668 |
| 60 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.72594646 |
| 61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.65858950 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.64279947 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62196135 |
| 64 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61321246 |
| 65 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.60758391 |
| 66 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.57414267 |
| 67 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.55314713 |
| 68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53420453 |
| 69 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.52034633 |
| 70 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.49534553 |
| 71 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49204982 |
| 72 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.48671796 |
| 73 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.48335873 |
| 74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.47814048 |
| 75 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.44637090 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.43356296 |
| 77 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.42961828 |
| 78 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39605392 |
| 79 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.39140626 |
| 80 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.37087029 |
| 81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.36515903 |
| 82 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.35074126 |
| 83 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.34580032 |
| 84 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.34436801 |
| 85 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.33217441 |
| 86 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.32543766 |
| 87 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.30924065 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.30298593 |
| 89 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.29070422 |
| 90 | Morphine addiction_Homo sapiens_hsa05032 | 0.28644569 |
| 91 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.28454458 |
| 92 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.28432080 |
| 93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.28161790 |
| 94 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.26538188 |
| 95 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.25909687 |
| 96 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25164013 |
| 97 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.24309549 |
| 98 | Insulin secretion_Homo sapiens_hsa04911 | 0.23415312 |
| 99 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.21956312 |
| 100 | Taste transduction_Homo sapiens_hsa04742 | 0.21187028 |

