

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chaperone-mediated protein transport (GO:0072321) | 5.51868705 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 5.37814016 |
| 3 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.03345241 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.02090956 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.02090956 |
| 6 | ribosomal small subunit biogenesis (GO:0042274) | 4.69344589 |
| 7 | viral transcription (GO:0019083) | 4.66780159 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.63148197 |
| 9 | behavioral response to nicotine (GO:0035095) | 4.62502241 |
| 10 | response to pheromone (GO:0019236) | 4.62003182 |
| 11 | translational termination (GO:0006415) | 4.56391535 |
| 12 | maturation of SSU-rRNA (GO:0030490) | 4.28971072 |
| 13 | protein neddylation (GO:0045116) | 4.28304151 |
| 14 | DNA deamination (GO:0045006) | 4.06283606 |
| 15 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.05042184 |
| 16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.99642090 |
| 17 | cotranslational protein targeting to membrane (GO:0006613) | 3.95688557 |
| 18 | protein targeting to ER (GO:0045047) | 3.92884306 |
| 19 | translational elongation (GO:0006414) | 3.83891400 |
| 20 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.80076805 |
| 21 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.78547086 |
| 22 | peptidyl-histidine modification (GO:0018202) | 3.74803288 |
| 23 | protein localization to endoplasmic reticulum (GO:0070972) | 3.68597209 |
| 24 | respiratory electron transport chain (GO:0022904) | 3.63345130 |
| 25 | electron transport chain (GO:0022900) | 3.61497461 |
| 26 | DNA double-strand break processing (GO:0000729) | 3.61001221 |
| 27 | respiratory chain complex IV assembly (GO:0008535) | 3.53506740 |
| 28 | cellular protein complex disassembly (GO:0043624) | 3.52482479 |
| 29 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.51413557 |
| 30 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.51413557 |
| 31 | NADH dehydrogenase complex assembly (GO:0010257) | 3.51413557 |
| 32 | translational initiation (GO:0006413) | 3.50076628 |
| 33 | protein complex biogenesis (GO:0070271) | 3.44645663 |
| 34 | translation (GO:0006412) | 3.31722839 |
| 35 | replication fork processing (GO:0031297) | 3.31722712 |
| 36 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.30703761 |
| 37 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.30451523 |
| 38 | pseudouridine synthesis (GO:0001522) | 3.29674742 |
| 39 | viral life cycle (GO:0019058) | 3.28071782 |
| 40 | axonemal dynein complex assembly (GO:0070286) | 3.27757680 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.19979125 |
| 42 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.11411128 |
| 43 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.11309198 |
| 44 | base-excision repair, AP site formation (GO:0006285) | 3.06907378 |
| 45 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.06058211 |
| 46 | protein complex disassembly (GO:0043241) | 3.05882153 |
| 47 | cytochrome complex assembly (GO:0017004) | 3.05356536 |
| 48 | macromolecular complex disassembly (GO:0032984) | 2.99980103 |
| 49 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.96000733 |
| 50 | ATP biosynthetic process (GO:0006754) | 2.94513963 |
| 51 | intracellular protein transmembrane import (GO:0044743) | 2.93633507 |
| 52 | hydrogen ion transmembrane transport (GO:1902600) | 2.90470133 |
| 53 | inositol phosphate catabolic process (GO:0071545) | 2.89576934 |
| 54 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.89077003 |
| 55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.89077003 |
| 56 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.86593880 |
| 57 | ubiquinone biosynthetic process (GO:0006744) | 2.85707233 |
| 58 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.83426722 |
| 59 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.82913649 |
| 60 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.82085483 |
| 61 | termination of RNA polymerase III transcription (GO:0006386) | 2.82085483 |
| 62 | proteasome assembly (GO:0043248) | 2.81452391 |
| 63 | protein-cofactor linkage (GO:0018065) | 2.80993616 |
| 64 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.80652441 |
| 65 | inositol phosphate dephosphorylation (GO:0046855) | 2.76629871 |
| 66 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.76629871 |
| 67 | epithelial cilium movement (GO:0003351) | 2.76472803 |
| 68 | cellular component biogenesis (GO:0044085) | 2.76085674 |
| 69 | L-serine metabolic process (GO:0006563) | 2.72046401 |
| 70 | chromatin remodeling at centromere (GO:0031055) | 2.71798575 |
| 71 | proton transport (GO:0015992) | 2.71536412 |
| 72 | cilium movement (GO:0003341) | 2.71282675 |
| 73 | ribosomal large subunit biogenesis (GO:0042273) | 2.70667492 |
| 74 | ncRNA catabolic process (GO:0034661) | 2.70316546 |
| 75 | regulation of collateral sprouting (GO:0048670) | 2.67060496 |
| 76 | hydrogen transport (GO:0006818) | 2.66504083 |
| 77 | organelle disassembly (GO:1903008) | 2.65743502 |
| 78 | protein targeting to membrane (GO:0006612) | 2.63185984 |
| 79 | resolution of meiotic recombination intermediates (GO:0000712) | 2.61553460 |
| 80 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.61523337 |
| 81 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.61170451 |
| 82 | protein polyglutamylation (GO:0018095) | 2.60104069 |
| 83 | myoblast migration (GO:0051451) | 2.59711501 |
| 84 | ubiquinone metabolic process (GO:0006743) | 2.58598687 |
| 85 | negative regulation of telomere maintenance (GO:0032205) | 2.58562523 |
| 86 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.54216681 |
| 87 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.53995848 |
| 88 | tongue development (GO:0043586) | 2.53814587 |
| 89 | regulation of cilium movement (GO:0003352) | 2.53813904 |
| 90 | cell proliferation in forebrain (GO:0021846) | 2.50781667 |
| 91 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.50317871 |
| 92 | nonmotile primary cilium assembly (GO:0035058) | 2.48302935 |
| 93 | rRNA processing (GO:0006364) | 2.47776240 |
| 94 | RNA phosphodiester bond hydrolysis, endonucleolytic (GO:0090502) | 2.46984146 |
| 95 | tRNA processing (GO:0008033) | 2.46313331 |
| 96 | GTP biosynthetic process (GO:0006183) | 2.46179322 |
| 97 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.45660027 |
| 98 | L-methionine salvage (GO:0071267) | 2.45634925 |
| 99 | L-methionine biosynthetic process (GO:0071265) | 2.45634925 |
| 100 | amino acid salvage (GO:0043102) | 2.45634925 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.32425981 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.68074777 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.53339548 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.34591579 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.19997832 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 3.01264981 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.89384724 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.72165317 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.63216260 |
| 10 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.62846354 |
| 11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.46353042 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.39116533 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.32480474 |
| 14 | EWS_26573619_Chip-Seq_HEK293_Human | 2.22780380 |
| 15 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.21556590 |
| 16 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.15148260 |
| 17 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.01457828 |
| 18 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.96436974 |
| 19 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.88498086 |
| 20 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.86762130 |
| 21 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.86747939 |
| 22 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.84719034 |
| 23 | FUS_26573619_Chip-Seq_HEK293_Human | 1.80200470 |
| 24 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.75305104 |
| 25 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.74045787 |
| 26 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.71454324 |
| 27 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.59936559 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.59841557 |
| 29 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.57935997 |
| 30 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.52026319 |
| 31 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.50530675 |
| 32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.49091004 |
| 33 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.46700742 |
| 34 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.44354727 |
| 35 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.43979217 |
| 36 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.42049739 |
| 37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.41998569 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.41811169 |
| 39 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.40866896 |
| 40 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.40599205 |
| 41 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.39523480 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35488558 |
| 43 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.33318258 |
| 44 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.33075772 |
| 45 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31545530 |
| 46 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.31211233 |
| 47 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29301077 |
| 48 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.26609154 |
| 49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.25631105 |
| 50 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.23383172 |
| 51 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.23285103 |
| 52 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.23144258 |
| 53 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.22717100 |
| 54 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.21174473 |
| 55 | NCOR_22424771_ChIP-Seq_293T_Human | 1.19187576 |
| 56 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.17809940 |
| 57 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.17423421 |
| 58 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.16186512 |
| 59 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.14497320 |
| 60 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.13013100 |
| 61 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12233745 |
| 62 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.10266874 |
| 63 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.08705556 |
| 64 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.05613477 |
| 65 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.05372794 |
| 66 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.04980370 |
| 67 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.04589114 |
| 68 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.04084695 |
| 69 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.03946410 |
| 70 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03591456 |
| 71 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02663733 |
| 72 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02663733 |
| 73 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.02501660 |
| 74 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.02032486 |
| 75 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.01890296 |
| 76 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.01718156 |
| 77 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.01718156 |
| 78 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.00372336 |
| 79 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99825820 |
| 80 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.99767717 |
| 81 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.98569823 |
| 82 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.97760430 |
| 83 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.96272944 |
| 84 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.95962937 |
| 85 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95541669 |
| 86 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.93562130 |
| 87 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.92472300 |
| 88 | AR_20517297_ChIP-Seq_VCAP_Human | 0.89053356 |
| 89 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.88862891 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.88498667 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.87123719 |
| 92 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.86847312 |
| 93 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.85873492 |
| 94 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.85873492 |
| 95 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.85332650 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.84614690 |
| 97 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.84115690 |
| 98 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.83570479 |
| 99 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.83397512 |
| 100 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.83315395 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.82500356 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.28065313 |
| 3 | MP0001984_abnormal_olfaction | 3.05556413 |
| 4 | MP0009379_abnormal_foot_pigmentation | 3.02269103 |
| 5 | MP0003787_abnormal_imprinting | 2.47645183 |
| 6 | MP0002102_abnormal_ear_morphology | 2.46253575 |
| 7 | MP0008789_abnormal_olfactory_epithelium | 2.43445106 |
| 8 | MP0003122_maternal_imprinting | 2.30110300 |
| 9 | MP0005499_abnormal_olfactory_system | 2.10399636 |
| 10 | MP0005394_taste/olfaction_phenotype | 2.10399636 |
| 11 | MP0001293_anophthalmia | 2.07004264 |
| 12 | MP0001968_abnormal_touch/_nociception | 1.98001067 |
| 13 | MP0002736_abnormal_nociception_after | 1.94773421 |
| 14 | MP0001485_abnormal_pinna_reflex | 1.91914317 |
| 15 | MP0008058_abnormal_DNA_repair | 1.88871466 |
| 16 | MP0003121_genomic_imprinting | 1.87836962 |
| 17 | MP0004142_abnormal_muscle_tone | 1.81735857 |
| 18 | MP0001529_abnormal_vocalization | 1.74582998 |
| 19 | MP0000778_abnormal_nervous_system | 1.74209812 |
| 20 | MP0002653_abnormal_ependyma_morphology | 1.72238787 |
| 21 | MP0005646_abnormal_pituitary_gland | 1.70049345 |
| 22 | MP0003136_yellow_coat_color | 1.69954667 |
| 23 | MP0002638_abnormal_pupillary_reflex | 1.68723913 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.64109365 |
| 25 | MP0002938_white_spotting | 1.62874203 |
| 26 | MP0006072_abnormal_retinal_apoptosis | 1.61211667 |
| 27 | MP0005551_abnormal_eye_electrophysiolog | 1.59782247 |
| 28 | MP0009745_abnormal_behavioral_response | 1.58730682 |
| 29 | MP0002272_abnormal_nervous_system | 1.58402831 |
| 30 | MP0003718_maternal_effect | 1.53619730 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.44218554 |
| 32 | MP0000049_abnormal_middle_ear | 1.44030608 |
| 33 | MP0003646_muscle_fatigue | 1.43719829 |
| 34 | MP0004885_abnormal_endolymph | 1.42872598 |
| 35 | MP0004133_heterotaxia | 1.42058047 |
| 36 | MP0008872_abnormal_physiological_respon | 1.41715362 |
| 37 | MP0003890_abnormal_embryonic-extraembry | 1.40281701 |
| 38 | MP0001188_hyperpigmentation | 1.38602170 |
| 39 | MP0002837_dystrophic_cardiac_calcinosis | 1.37159318 |
| 40 | MP0001905_abnormal_dopamine_level | 1.36902264 |
| 41 | MP0000631_abnormal_neuroendocrine_gland | 1.36830698 |
| 42 | MP0003567_abnormal_fetal_cardiomyocyte | 1.34665519 |
| 43 | MP0009046_muscle_twitch | 1.34128606 |
| 44 | MP0005377_hearing/vestibular/ear_phenot | 1.28660063 |
| 45 | MP0003878_abnormal_ear_physiology | 1.28660063 |
| 46 | MP0002160_abnormal_reproductive_system | 1.26738572 |
| 47 | MP0003123_paternal_imprinting | 1.21736312 |
| 48 | MP0003315_abnormal_perineum_morphology | 1.18413320 |
| 49 | MP0004145_abnormal_muscle_electrophysio | 1.17035907 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.16531044 |
| 51 | MP0002572_abnormal_emotion/affect_behav | 1.13863736 |
| 52 | MP0002557_abnormal_social/conspecific_i | 1.12924091 |
| 53 | MP0001486_abnormal_startle_reflex | 1.12605265 |
| 54 | MP0005410_abnormal_fertilization | 1.11809282 |
| 55 | MP0004742_abnormal_vestibular_system | 1.11602625 |
| 56 | MP0003937_abnormal_limbs/digits/tail_de | 1.10417438 |
| 57 | MP0003186_abnormal_redox_activity | 1.07921692 |
| 58 | MP0002277_abnormal_respiratory_mucosa | 1.07921657 |
| 59 | MP0005379_endocrine/exocrine_gland_phen | 1.07663149 |
| 60 | MP0003635_abnormal_synaptic_transmissio | 1.07530833 |
| 61 | MP0005187_abnormal_penis_morphology | 1.07292120 |
| 62 | MP0002752_abnormal_somatic_nervous | 1.06397243 |
| 63 | MP0002210_abnormal_sex_determination | 1.05022835 |
| 64 | MP0005195_abnormal_posterior_eye | 1.03128726 |
| 65 | MP0006035_abnormal_mitochondrial_morpho | 1.01857640 |
| 66 | MP0002063_abnormal_learning/memory/cond | 0.98946751 |
| 67 | MP0002733_abnormal_thermal_nociception | 0.98859443 |
| 68 | MP0002163_abnormal_gland_morphology | 0.98210154 |
| 69 | MP0001970_abnormal_pain_threshold | 0.98021619 |
| 70 | MP0005253_abnormal_eye_physiology | 0.98019795 |
| 71 | MP0003880_abnormal_central_pattern | 0.97675052 |
| 72 | MP0005389_reproductive_system_phenotype | 0.96290219 |
| 73 | MP0010030_abnormal_orbit_morphology | 0.95688609 |
| 74 | MP0002184_abnormal_innervation | 0.94356770 |
| 75 | MP0003693_abnormal_embryo_hatching | 0.94313798 |
| 76 | MP0002233_abnormal_nose_morphology | 0.93720616 |
| 77 | MP0000516_abnormal_urinary_system | 0.93417677 |
| 78 | MP0005367_renal/urinary_system_phenotyp | 0.93417677 |
| 79 | MP0001348_abnormal_lacrimal_gland | 0.93089468 |
| 80 | MP0000955_abnormal_spinal_cord | 0.90986835 |
| 81 | MP0003786_premature_aging | 0.90932987 |
| 82 | MP0002067_abnormal_sensory_capabilities | 0.89377412 |
| 83 | MP0009053_abnormal_anal_canal | 0.88041880 |
| 84 | MP0001986_abnormal_taste_sensitivity | 0.88008195 |
| 85 | MP0002064_seizures | 0.87898168 |
| 86 | MP0003698_abnormal_male_reproductive | 0.87768839 |
| 87 | MP0003938_abnormal_ear_development | 0.86921214 |
| 88 | MP0000566_synostosis | 0.86377250 |
| 89 | MP0000372_irregular_coat_pigmentation | 0.86331147 |
| 90 | MP0003011_delayed_dark_adaptation | 0.86296923 |
| 91 | MP0001929_abnormal_gametogenesis | 0.86259874 |
| 92 | MP0003119_abnormal_digestive_system | 0.86041215 |
| 93 | MP0002735_abnormal_chemical_nociception | 0.85324191 |
| 94 | MP0001177_atelectasis | 0.84804795 |
| 95 | MP0000026_abnormal_inner_ear | 0.84348817 |
| 96 | MP0004859_abnormal_synaptic_plasticity | 0.84161396 |
| 97 | MP0006036_abnormal_mitochondrial_physio | 0.82917388 |
| 98 | MP0004147_increased_porphyrin_level | 0.80657504 |
| 99 | MP0001440_abnormal_grooming_behavior | 0.80408452 |
| 100 | MP0004924_abnormal_behavior | 0.79374896 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.98640616 |
| 2 | Progressive macrocephaly (HP:0004481) | 3.67484437 |
| 3 | Acute encephalopathy (HP:0006846) | 3.59450840 |
| 4 | Abnormality of the labia minora (HP:0012880) | 3.49930992 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.46290740 |
| 6 | Molar tooth sign on MRI (HP:0002419) | 3.42806144 |
| 7 | Abnormality of midbrain morphology (HP:0002418) | 3.42806144 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.42530861 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.35335348 |
| 10 | Pancreatic fibrosis (HP:0100732) | 3.34414526 |
| 11 | Septo-optic dysplasia (HP:0100842) | 3.30391318 |
| 12 | Reticulocytopenia (HP:0001896) | 3.26755399 |
| 13 | Increased CSF lactate (HP:0002490) | 3.20263416 |
| 14 | Lipid accumulation in hepatocytes (HP:0006561) | 3.13592495 |
| 15 | Pancreatic cysts (HP:0001737) | 3.10182280 |
| 16 | Renal Fanconi syndrome (HP:0001994) | 3.04684803 |
| 17 | Supernumerary spleens (HP:0009799) | 2.88523017 |
| 18 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.88147919 |
| 19 | True hermaphroditism (HP:0010459) | 2.82262880 |
| 20 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.77138048 |
| 21 | Congenital stationary night blindness (HP:0007642) | 2.69161116 |
| 22 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.65788900 |
| 23 | Abnormal ciliary motility (HP:0012262) | 2.62447142 |
| 24 | Macrocytic anemia (HP:0001972) | 2.59846029 |
| 25 | Type 2 muscle fiber atrophy (HP:0003554) | 2.59463746 |
| 26 | Absent thumb (HP:0009777) | 2.58029733 |
| 27 | Cerebral edema (HP:0002181) | 2.55501573 |
| 28 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.50775985 |
| 29 | Absent/shortened dynein arms (HP:0200106) | 2.46324072 |
| 30 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.46324072 |
| 31 | Optic disc pallor (HP:0000543) | 2.44849167 |
| 32 | Absent septum pellucidum (HP:0001331) | 2.43918429 |
| 33 | Increased serum lactate (HP:0002151) | 2.43851813 |
| 34 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.42731081 |
| 35 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.42731081 |
| 36 | Hepatocellular necrosis (HP:0001404) | 2.42497277 |
| 37 | Hyperglycinemia (HP:0002154) | 2.42460179 |
| 38 | Colon cancer (HP:0003003) | 2.42178857 |
| 39 | Chronic hepatic failure (HP:0100626) | 2.39355997 |
| 40 | Nephronophthisis (HP:0000090) | 2.38090753 |
| 41 | Sclerocornea (HP:0000647) | 2.38082772 |
| 42 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.36782643 |
| 43 | Increased intramyocellular lipid droplets (HP:0012240) | 2.31785019 |
| 44 | Muscle fiber atrophy (HP:0100295) | 2.30994289 |
| 45 | Medial flaring of the eyebrow (HP:0010747) | 2.30992571 |
| 46 | Abolished electroretinogram (ERG) (HP:0000550) | 2.30939309 |
| 47 | 3-Methylglutaconic aciduria (HP:0003535) | 2.27789721 |
| 48 | Abnormality of the septum pellucidum (HP:0007375) | 2.25776915 |
| 49 | Occipital encephalocele (HP:0002085) | 2.25707664 |
| 50 | Poor suck (HP:0002033) | 2.25624466 |
| 51 | Anencephaly (HP:0002323) | 2.18911314 |
| 52 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.17776604 |
| 53 | Lactic acidosis (HP:0003128) | 2.16476420 |
| 54 | Asplenia (HP:0001746) | 2.15951749 |
| 55 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.15577214 |
| 56 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.12574692 |
| 57 | Exertional dyspnea (HP:0002875) | 2.12197044 |
| 58 | Stenosis of the external auditory canal (HP:0000402) | 2.09056413 |
| 59 | Retinal dysplasia (HP:0007973) | 2.05468203 |
| 60 | Optic nerve hypoplasia (HP:0000609) | 2.04536257 |
| 61 | Hepatic necrosis (HP:0002605) | 2.04214654 |
| 62 | Pendular nystagmus (HP:0012043) | 2.03157410 |
| 63 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.00994067 |
| 64 | Abnormal drinking behavior (HP:0030082) | 1.98520664 |
| 65 | Polydipsia (HP:0001959) | 1.98520664 |
| 66 | Meckel diverticulum (HP:0002245) | 1.98034470 |
| 67 | Abnormal number of erythroid precursors (HP:0012131) | 1.97127658 |
| 68 | Pallor (HP:0000980) | 1.96932496 |
| 69 | Gait imbalance (HP:0002141) | 1.96921281 |
| 70 | Polyphagia (HP:0002591) | 1.95253833 |
| 71 | Abnormality of the ileum (HP:0001549) | 1.93533385 |
| 72 | Cystic liver disease (HP:0006706) | 1.90051649 |
| 73 | Abnormality of the renal medulla (HP:0100957) | 1.89012485 |
| 74 | Neoplasm of the adrenal cortex (HP:0100641) | 1.88162329 |
| 75 | Increased muscle lipid content (HP:0009058) | 1.88136982 |
| 76 | Abnormality of renal resorption (HP:0011038) | 1.87909611 |
| 77 | Hyperthyroidism (HP:0000836) | 1.87807871 |
| 78 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.87330308 |
| 79 | Lethargy (HP:0001254) | 1.86564948 |
| 80 | Rib fusion (HP:0000902) | 1.85875648 |
| 81 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.84161928 |
| 82 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.82746673 |
| 83 | Congenital primary aphakia (HP:0007707) | 1.82631688 |
| 84 | Hyperphosphaturia (HP:0003109) | 1.82532188 |
| 85 | Genital tract atresia (HP:0001827) | 1.81558296 |
| 86 | Respiratory failure (HP:0002878) | 1.81498193 |
| 87 | Abnormality of serum amino acid levels (HP:0003112) | 1.81338476 |
| 88 | Abnormal number of incisors (HP:0011064) | 1.80899056 |
| 89 | Narrow forehead (HP:0000341) | 1.79651154 |
| 90 | Triphalangeal thumb (HP:0001199) | 1.78313390 |
| 91 | Vaginal atresia (HP:0000148) | 1.76591339 |
| 92 | Pachygyria (HP:0001302) | 1.76079723 |
| 93 | Postaxial foot polydactyly (HP:0001830) | 1.74854149 |
| 94 | Abnormality of alanine metabolism (HP:0010916) | 1.74339768 |
| 95 | Hyperalaninemia (HP:0003348) | 1.74339768 |
| 96 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.74339768 |
| 97 | Male pseudohermaphroditism (HP:0000037) | 1.74111950 |
| 98 | Optic nerve coloboma (HP:0000588) | 1.73600935 |
| 99 | Bile duct proliferation (HP:0001408) | 1.73152204 |
| 100 | Abnormal biliary tract physiology (HP:0012439) | 1.73152204 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 3.95596438 |
| 2 | PINK1 | 3.27835562 |
| 3 | WNK4 | 3.14957138 |
| 4 | ZAK | 2.48276102 |
| 5 | DYRK2 | 2.47443716 |
| 6 | WNK3 | 2.44292663 |
| 7 | STK16 | 2.24819861 |
| 8 | BCKDK | 2.16891253 |
| 9 | BMPR1B | 2.09991546 |
| 10 | ADRBK2 | 2.01971532 |
| 11 | TNIK | 1.91132829 |
| 12 | STK39 | 1.90750696 |
| 13 | VRK2 | 1.88363150 |
| 14 | NUAK1 | 1.80680931 |
| 15 | SRPK1 | 1.74804274 |
| 16 | CDC7 | 1.71569522 |
| 17 | GRK1 | 1.70709819 |
| 18 | LIMK1 | 1.69328094 |
| 19 | MKNK2 | 1.68044941 |
| 20 | CAMKK2 | 1.65724113 |
| 21 | FGFR2 | 1.58559138 |
| 22 | PLK3 | 1.42435306 |
| 23 | TLK1 | 1.38572294 |
| 24 | BUB1 | 1.26165949 |
| 25 | MAP3K12 | 1.22616793 |
| 26 | PAK3 | 1.21128903 |
| 27 | ACVR1B | 1.21114528 |
| 28 | VRK1 | 1.14489113 |
| 29 | PIK3CA | 1.13671055 |
| 30 | MAPK13 | 1.11898399 |
| 31 | PLK2 | 1.11889871 |
| 32 | NEK1 | 1.11096920 |
| 33 | PRKCG | 1.11055399 |
| 34 | PLK4 | 1.09773892 |
| 35 | MARK1 | 1.09552544 |
| 36 | PLK1 | 1.09035447 |
| 37 | TXK | 1.05238156 |
| 38 | MAP3K11 | 1.03208351 |
| 39 | EIF2AK1 | 1.02689623 |
| 40 | CAMK1D | 1.02296591 |
| 41 | OXSR1 | 1.01062807 |
| 42 | CASK | 0.96777419 |
| 43 | EPHB2 | 0.93574388 |
| 44 | TIE1 | 0.93166883 |
| 45 | MKNK1 | 0.89545802 |
| 46 | MAP2K7 | 0.88929969 |
| 47 | CAMK1 | 0.82553177 |
| 48 | PDK2 | 0.82505865 |
| 49 | NME2 | 0.82198573 |
| 50 | RPS6KA5 | 0.81976558 |
| 51 | MINK1 | 0.80926007 |
| 52 | KDR | 0.79437629 |
| 53 | CSNK1G2 | 0.79297034 |
| 54 | MAP3K9 | 0.79127380 |
| 55 | PRKCQ | 0.78682568 |
| 56 | TSSK6 | 0.77615381 |
| 57 | INSRR | 0.76911376 |
| 58 | CSNK1G1 | 0.72855253 |
| 59 | AURKA | 0.71969150 |
| 60 | MST4 | 0.68968609 |
| 61 | MAP4K2 | 0.68067611 |
| 62 | NTRK2 | 0.67770913 |
| 63 | TGFBR1 | 0.67219068 |
| 64 | CDK19 | 0.66161123 |
| 65 | PRKCE | 0.65641651 |
| 66 | PRKCI | 0.65181502 |
| 67 | DYRK3 | 0.64454215 |
| 68 | PRKCZ | 0.62904741 |
| 69 | PBK | 0.62538765 |
| 70 | PASK | 0.62167747 |
| 71 | ADRBK1 | 0.61621912 |
| 72 | CAMK1G | 0.61442642 |
| 73 | SGK223 | 0.61196297 |
| 74 | SGK494 | 0.61196297 |
| 75 | ATR | 0.60787423 |
| 76 | NME1 | 0.59649951 |
| 77 | TRIM28 | 0.59275625 |
| 78 | CSNK1G3 | 0.58625400 |
| 79 | PHKG2 | 0.58014832 |
| 80 | PHKG1 | 0.58014832 |
| 81 | CSNK2A2 | 0.57234335 |
| 82 | WNK1 | 0.56192765 |
| 83 | CAMK2A | 0.54146980 |
| 84 | CSNK1E | 0.53763687 |
| 85 | AURKB | 0.52866587 |
| 86 | EIF2AK3 | 0.51587313 |
| 87 | CAMKK1 | 0.51542797 |
| 88 | PRKCH | 0.51322242 |
| 89 | TAF1 | 0.51213806 |
| 90 | OBSCN | 0.49604174 |
| 91 | LRRK2 | 0.49519313 |
| 92 | TAOK3 | 0.49458082 |
| 93 | ROCK1 | 0.48896005 |
| 94 | CDK3 | 0.48751216 |
| 95 | CSNK2A1 | 0.48233655 |
| 96 | PRKACA | 0.47850194 |
| 97 | MAP3K4 | 0.44823707 |
| 98 | DYRK1A | 0.43357073 |
| 99 | TTK | 0.43091310 |
| 100 | RPS6KA4 | 0.41868822 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.48806098 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.95883876 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.42276866 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.62127280 |
| 5 | Huntingtons disease_Homo sapiens_hsa05016 | 2.49853740 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 2.49478215 |
| 7 | Homologous recombination_Homo sapiens_hsa03440 | 2.30939915 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.21257167 |
| 9 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.18514280 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.16436489 |
| 11 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.11427944 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.06932197 |
| 13 | Protein export_Homo sapiens_hsa03060 | 2.04543428 |
| 14 | Mismatch repair_Homo sapiens_hsa03430 | 2.00354656 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.93076211 |
| 16 | Basal transcription factors_Homo sapiens_hsa03022 | 1.91259004 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.89894587 |
| 18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.87398815 |
| 19 | Phototransduction_Homo sapiens_hsa04744 | 1.72368746 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.71841539 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.68671314 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.68621242 |
| 23 | DNA replication_Homo sapiens_hsa03030 | 1.64185948 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.54923095 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.54643646 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.43483072 |
| 27 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.40321036 |
| 28 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.38758847 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.38643975 |
| 30 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.38456030 |
| 31 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.35431447 |
| 32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.34937761 |
| 33 | Nicotine addiction_Homo sapiens_hsa05033 | 1.30091876 |
| 34 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.28360772 |
| 35 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.28315237 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.25243746 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.25016535 |
| 38 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.20493919 |
| 39 | Sulfur relay system_Homo sapiens_hsa04122 | 1.19503035 |
| 40 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.19332776 |
| 41 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.13098768 |
| 42 | Spliceosome_Homo sapiens_hsa03040 | 1.12482717 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 1.07715391 |
| 44 | RNA transport_Homo sapiens_hsa03013 | 1.06966178 |
| 45 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.06418733 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.04097203 |
| 47 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02377352 |
| 48 | Base excision repair_Homo sapiens_hsa03410 | 0.99004683 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.96653987 |
| 50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.93423464 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.90294368 |
| 52 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.87676117 |
| 53 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.82207099 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.81767905 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.81274329 |
| 56 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.77493050 |
| 57 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.75315357 |
| 58 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.73957709 |
| 59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.72841801 |
| 60 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.67237650 |
| 61 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.62623166 |
| 62 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.59486406 |
| 63 | Taste transduction_Homo sapiens_hsa04742 | 0.59234357 |
| 64 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.59166113 |
| 65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.58143275 |
| 66 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.57730176 |
| 67 | Morphine addiction_Homo sapiens_hsa05032 | 0.57542588 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.55954194 |
| 69 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.54827420 |
| 70 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.53121282 |
| 71 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.48495066 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.48232413 |
| 73 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.46603552 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.46481047 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.45676760 |
| 76 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44787463 |
| 77 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.44216228 |
| 78 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.43765533 |
| 79 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.43337948 |
| 80 | GABAergic synapse_Homo sapiens_hsa04727 | 0.41778912 |
| 81 | Retinol metabolism_Homo sapiens_hsa00830 | 0.40899585 |
| 82 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.40502023 |
| 83 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.39960533 |
| 84 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.38702827 |
| 85 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.36720940 |
| 86 | Insulin secretion_Homo sapiens_hsa04911 | 0.34678503 |
| 87 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.32934787 |
| 88 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.32307504 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.30436388 |
| 90 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.29240279 |
| 91 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.25341933 |
| 92 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.23855590 |
| 93 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.23364931 |
| 94 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.23099040 |
| 95 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.19594150 |
| 96 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.16355140 |
| 97 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.15847786 |
| 98 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.14759468 |
| 99 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.14384579 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.13660568 |

