

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | monoubiquitinated protein deubiquitination (GO:0035520) | 8.24449020 |
| 2 | water-soluble vitamin biosynthetic process (GO:0042364) | 7.04328801 |
| 3 | protein complex biogenesis (GO:0070271) | 6.16367160 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 5.60428131 |
| 5 | mitochondrial respiratory chain complex assembly (GO:0033108) | 5.56746964 |
| 6 | base-excision repair, AP site formation (GO:0006285) | 5.41438234 |
| 7 | regulation of mitochondrial translation (GO:0070129) | 5.39528769 |
| 8 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 5.29365737 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 5.21482999 |
| 10 | negative regulation of membrane potential (GO:0045837) | 4.89653862 |
| 11 | positive regulation of interleukin-17 production (GO:0032740) | 4.77372822 |
| 12 | cytochrome complex assembly (GO:0017004) | 4.68996095 |
| 13 | DNA deamination (GO:0045006) | 4.66128037 |
| 14 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.61412898 |
| 15 | NADH dehydrogenase complex assembly (GO:0010257) | 4.61412898 |
| 16 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.61412898 |
| 17 | pseudouridine synthesis (GO:0001522) | 4.54421022 |
| 18 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.39760837 |
| 19 | proteasome assembly (GO:0043248) | 4.23378011 |
| 20 | cytidine metabolic process (GO:0046087) | 4.07869954 |
| 21 | cytidine catabolic process (GO:0006216) | 4.07869954 |
| 22 | cytidine deamination (GO:0009972) | 4.07869954 |
| 23 | protein deneddylation (GO:0000338) | 4.03434896 |
| 24 | behavioral response to nicotine (GO:0035095) | 3.95269163 |
| 25 | protein neddylation (GO:0045116) | 3.82684941 |
| 26 | ncRNA 3-end processing (GO:0043628) | 3.77901137 |
| 27 | vitamin biosynthetic process (GO:0009110) | 3.74766018 |
| 28 | maturation of 5.8S rRNA (GO:0000460) | 3.70774214 |
| 29 | deoxyribonucleotide catabolic process (GO:0009264) | 3.69588901 |
| 30 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.66838035 |
| 31 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.65455175 |
| 32 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.63862996 |
| 33 | histone deubiquitination (GO:0016578) | 3.60903788 |
| 34 | rRNA modification (GO:0000154) | 3.55754919 |
| 35 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.55087913 |
| 36 | deoxyribose phosphate catabolic process (GO:0046386) | 3.51323231 |
| 37 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.46361128 |
| 38 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.46328554 |
| 39 | protein import into peroxisome matrix (GO:0016558) | 3.45758007 |
| 40 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.44855765 |
| 41 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.39375122 |
| 42 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 3.26025153 |
| 43 | cellular component biogenesis (GO:0044085) | 3.23360812 |
| 44 | cobalamin metabolic process (GO:0009235) | 3.22125881 |
| 45 | termination of RNA polymerase III transcription (GO:0006386) | 3.18348077 |
| 46 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.18348077 |
| 47 | rRNA methylation (GO:0031167) | 3.16939133 |
| 48 | intracellular protein transmembrane import (GO:0044743) | 3.16581223 |
| 49 | transcription from mitochondrial promoter (GO:0006390) | 3.14991751 |
| 50 | adaptation of signaling pathway (GO:0023058) | 3.13150669 |
| 51 | platelet dense granule organization (GO:0060155) | 3.12656556 |
| 52 | regulation of regulatory T cell differentiation (GO:0045589) | 3.12471374 |
| 53 | autophagic vacuole fusion (GO:0000046) | 3.11674821 |
| 54 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.08881246 |
| 55 | positive regulation of DNA recombination (GO:0045911) | 3.06214246 |
| 56 | protein K48-linked deubiquitination (GO:0071108) | 3.05998038 |
| 57 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.03446381 |
| 58 | regulation of immunoglobulin secretion (GO:0051023) | 3.02049925 |
| 59 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.02013964 |
| 60 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.98833939 |
| 61 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.98609117 |
| 62 | cell wall macromolecule metabolic process (GO:0044036) | 2.98535966 |
| 63 | positive regulation of chemokine biosynthetic process (GO:0045080) | 2.98218626 |
| 64 | ribosomal large subunit biogenesis (GO:0042273) | 2.98196508 |
| 65 | response to nitric oxide (GO:0071731) | 2.96124602 |
| 66 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.95616782 |
| 67 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.89064186 |
| 68 | negative regulation of glycogen biosynthetic process (GO:0045719) | 2.88560351 |
| 69 | regulation of interleukin-17 production (GO:0032660) | 2.84448875 |
| 70 | positive regulation of endothelial cell differentiation (GO:0045603) | 2.83173928 |
| 71 | mitochondrial RNA metabolic process (GO:0000959) | 2.82995758 |
| 72 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.82565676 |
| 73 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.82565676 |
| 74 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.82565676 |
| 75 | cytokine biosynthetic process (GO:0042089) | 2.80919227 |
| 76 | positive regulation of ligase activity (GO:0051351) | 2.80130095 |
| 77 | iron-sulfur cluster assembly (GO:0016226) | 2.80065731 |
| 78 | metallo-sulfur cluster assembly (GO:0031163) | 2.80065731 |
| 79 | T cell migration (GO:0072678) | 2.79763211 |
| 80 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.79363474 |
| 81 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.79363474 |
| 82 | cellular response to interleukin-15 (GO:0071350) | 2.79256968 |
| 83 | regulation of chemokine biosynthetic process (GO:0045073) | 2.79157483 |
| 84 | positive regulation of isotype switching (GO:0045830) | 2.78817076 |
| 85 | forebrain morphogenesis (GO:0048853) | 2.78557744 |
| 86 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.76984240 |
| 87 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 2.74109959 |
| 88 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.72969737 |
| 89 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.72646901 |
| 90 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.69971792 |
| 91 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.69971792 |
| 92 | ATP synthesis coupled proton transport (GO:0015986) | 2.69735324 |
| 93 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.69735324 |
| 94 | GTP biosynthetic process (GO:0006183) | 2.69066209 |
| 95 | rRNA processing (GO:0006364) | 2.69041201 |
| 96 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.68627250 |
| 97 | negative regulation of ligase activity (GO:0051352) | 2.68627250 |
| 98 | viral transcription (GO:0019083) | 2.67779665 |
| 99 | protein localization to endoplasmic reticulum (GO:0070972) | 2.65588091 |
| 100 | regulation of podosome assembly (GO:0071801) | 2.64855704 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.35759170 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.02117328 |
| 3 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.91325182 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.89445567 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.74530777 |
| 6 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.71776986 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.27032572 |
| 8 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.22738625 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.16880156 |
| 10 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.93655228 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.86001041 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.81239431 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.77619160 |
| 14 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.55960040 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.49085417 |
| 16 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.47017320 |
| 17 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.45833471 |
| 18 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.23220382 |
| 19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.21428037 |
| 20 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.19592643 |
| 21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.17859734 |
| 22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.12078076 |
| 23 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.09798350 |
| 24 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.08174509 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.96139719 |
| 26 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.91066353 |
| 27 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.86196704 |
| 28 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.84279865 |
| 29 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.83423912 |
| 30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.80384618 |
| 31 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.78711478 |
| 32 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.66506997 |
| 33 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.62301380 |
| 34 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.57675830 |
| 35 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.55312501 |
| 36 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.54328356 |
| 37 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.52661390 |
| 38 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.50913891 |
| 39 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.50657518 |
| 40 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.48134130 |
| 41 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.46497105 |
| 42 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.43599842 |
| 43 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.43192424 |
| 44 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.39525331 |
| 45 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.37524126 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.35944282 |
| 47 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.35389530 |
| 48 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.33238116 |
| 49 | NCOR_22424771_ChIP-Seq_293T_Human | 1.31545256 |
| 50 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30176841 |
| 51 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.28347773 |
| 52 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.27209224 |
| 53 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.27128640 |
| 54 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.25342308 |
| 55 | GATA3_26560356_Chip-Seq_TH2_Human | 1.25147048 |
| 56 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.24500732 |
| 57 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.22795229 |
| 58 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.22570263 |
| 59 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.21995935 |
| 60 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.21259925 |
| 61 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19884419 |
| 62 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15473609 |
| 63 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.14466714 |
| 64 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.13813178 |
| 65 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.13477157 |
| 66 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.11363099 |
| 67 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.11170571 |
| 68 | MYB_26560356_Chip-Seq_TH2_Human | 1.10667972 |
| 69 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.09313045 |
| 70 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.09313045 |
| 71 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.08335675 |
| 72 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.07678942 |
| 73 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.07017588 |
| 74 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.06704082 |
| 75 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.06536217 |
| 76 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.05023180 |
| 77 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.03615473 |
| 78 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 1.01078046 |
| 79 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.99324130 |
| 80 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99116212 |
| 81 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.98633854 |
| 82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97980069 |
| 83 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.97488638 |
| 84 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.97421444 |
| 85 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.96415235 |
| 86 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.95531189 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.93697191 |
| 88 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.93031907 |
| 89 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.92855627 |
| 90 | ERA_21632823_ChIP-Seq_H3396_Human | 0.92184026 |
| 91 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.89093835 |
| 92 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.88338308 |
| 93 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.87622551 |
| 94 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.87009595 |
| 95 | P68_20966046_ChIP-Seq_HELA_Human | 0.86583538 |
| 96 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.86320264 |
| 97 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.86064647 |
| 98 | VDR_22108803_ChIP-Seq_LS180_Human | 0.84515298 |
| 99 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84450645 |
| 100 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.83970738 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 7.24808604 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 5.16336740 |
| 3 | MP0003122_maternal_imprinting | 3.29000993 |
| 4 | MP0002736_abnormal_nociception_after | 3.28672376 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.18219364 |
| 6 | MP0005671_abnormal_response_to | 2.72105385 |
| 7 | MP0001853_heart_inflammation | 2.71211806 |
| 8 | MP0001873_stomach_inflammation | 2.58314799 |
| 9 | MP0003123_paternal_imprinting | 2.51748749 |
| 10 | MP0001968_abnormal_touch/_nociception | 2.39779300 |
| 11 | MP0009333_abnormal_splenocyte_physiolog | 2.12088529 |
| 12 | MP0004185_abnormal_adipocyte_glucose | 2.11705096 |
| 13 | MP0003121_genomic_imprinting | 2.03961889 |
| 14 | MP0001905_abnormal_dopamine_level | 1.96232582 |
| 15 | MP0005670_abnormal_white_adipose | 1.90336443 |
| 16 | MP0009785_altered_susceptibility_to | 1.86426199 |
| 17 | MP0004742_abnormal_vestibular_system | 1.85991818 |
| 18 | MP0002148_abnormal_hypersensitivity_rea | 1.78836784 |
| 19 | MP0005084_abnormal_gallbladder_morpholo | 1.75959352 |
| 20 | MP0002277_abnormal_respiratory_mucosa | 1.75566583 |
| 21 | MP0009379_abnormal_foot_pigmentation | 1.75446157 |
| 22 | MP0008775_abnormal_heart_ventricle | 1.72259263 |
| 23 | MP0002138_abnormal_hepatobiliary_system | 1.64718806 |
| 24 | MP0002166_altered_tumor_susceptibility | 1.63932664 |
| 25 | MP0008789_abnormal_olfactory_epithelium | 1.63141662 |
| 26 | MP0008872_abnormal_physiological_respon | 1.58683133 |
| 27 | MP0003567_abnormal_fetal_cardiomyocyte | 1.53301240 |
| 28 | MP0001188_hyperpigmentation | 1.52569383 |
| 29 | MP0002102_abnormal_ear_morphology | 1.52350593 |
| 30 | MP0004133_heterotaxia | 1.48234692 |
| 31 | MP0001529_abnormal_vocalization | 1.47234845 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.34812227 |
| 33 | MP0003786_premature_aging | 1.33365198 |
| 34 | MP0006292_abnormal_olfactory_placode | 1.31045902 |
| 35 | MP0004145_abnormal_muscle_electrophysio | 1.28975400 |
| 36 | MP0003011_delayed_dark_adaptation | 1.28891863 |
| 37 | MP0000681_abnormal_thyroid_gland | 1.26755645 |
| 38 | MP0003878_abnormal_ear_physiology | 1.24687832 |
| 39 | MP0005377_hearing/vestibular/ear_phenot | 1.24687832 |
| 40 | MP0000678_abnormal_parathyroid_gland | 1.24158849 |
| 41 | MP0010155_abnormal_intestine_physiology | 1.23004041 |
| 42 | MP0003890_abnormal_embryonic-extraembry | 1.22413817 |
| 43 | MP0001661_extended_life_span | 1.20946331 |
| 44 | MP0008875_abnormal_xenobiotic_pharmacok | 1.17743023 |
| 45 | MP0001984_abnormal_olfaction | 1.16743514 |
| 46 | MP0005000_abnormal_immune_tolerance | 1.16228142 |
| 47 | MP0003866_abnormal_defecation | 1.13208386 |
| 48 | MP0002006_tumorigenesis | 1.13025332 |
| 49 | MP0005387_immune_system_phenotype | 1.12024146 |
| 50 | MP0001790_abnormal_immune_system | 1.12024146 |
| 51 | MP0003763_abnormal_thymus_physiology | 1.09377040 |
| 52 | MP0002693_abnormal_pancreas_physiology | 1.06966907 |
| 53 | MP0001800_abnormal_humoral_immune | 1.06308110 |
| 54 | MP0002928_abnormal_bile_duct | 1.05922571 |
| 55 | MP0008058_abnormal_DNA_repair | 1.04714754 |
| 56 | MP0005332_abnormal_amino_acid | 1.03983198 |
| 57 | MP0009384_cardiac_valve_regurgitation | 1.01365972 |
| 58 | MP0000343_altered_response_to | 0.99553112 |
| 59 | MP0009764_decreased_sensitivity_to | 0.94494322 |
| 60 | MP0008877_abnormal_DNA_methylation | 0.92096365 |
| 61 | MP0005083_abnormal_biliary_tract | 0.91663140 |
| 62 | MP0005389_reproductive_system_phenotype | 0.91303503 |
| 63 | MP0000537_abnormal_urethra_morphology | 0.90488170 |
| 64 | MP0000538_abnormal_urinary_bladder | 0.90071502 |
| 65 | MP0005025_abnormal_response_to | 0.89257676 |
| 66 | MP0003806_abnormal_nucleotide_metabolis | 0.87757703 |
| 67 | MP0004782_abnormal_surfactant_physiolog | 0.87628232 |
| 68 | MP0001764_abnormal_homeostasis | 0.86899047 |
| 69 | MP0005666_abnormal_adipose_tissue | 0.86068456 |
| 70 | MP0005365_abnormal_bile_salt | 0.85925731 |
| 71 | MP0002938_white_spotting | 0.85119039 |
| 72 | MP0002132_abnormal_respiratory_system | 0.85043988 |
| 73 | MP0002160_abnormal_reproductive_system | 0.83963205 |
| 74 | MP0002735_abnormal_chemical_nociception | 0.82393808 |
| 75 | MP0006036_abnormal_mitochondrial_physio | 0.78832255 |
| 76 | MP0003252_abnormal_bile_duct | 0.78088008 |
| 77 | MP0004130_abnormal_muscle_cell | 0.76607804 |
| 78 | MP0006082_CNS_inflammation | 0.74978664 |
| 79 | MP0005645_abnormal_hypothalamus_physiol | 0.74497634 |
| 80 | MP0000230_abnormal_systemic_arterial | 0.73717656 |
| 81 | MP0000049_abnormal_middle_ear | 0.73712335 |
| 82 | MP0001919_abnormal_reproductive_system | 0.73697651 |
| 83 | MP0004147_increased_porphyrin_level | 0.73159120 |
| 84 | MP0005551_abnormal_eye_electrophysiolog | 0.72834668 |
| 85 | MP0002420_abnormal_adaptive_immunity | 0.72056584 |
| 86 | MP0004924_abnormal_behavior | 0.71987095 |
| 87 | MP0005386_behavior/neurological_phenoty | 0.71987095 |
| 88 | MP0001727_abnormal_embryo_implantation | 0.71911777 |
| 89 | MP0002723_abnormal_immune_serum | 0.70909693 |
| 90 | MP0005408_hypopigmentation | 0.70085688 |
| 91 | MP0001819_abnormal_immune_cell | 0.69754996 |
| 92 | MP0002933_joint_inflammation | 0.69424695 |
| 93 | MP0001270_distended_abdomen | 0.67140193 |
| 94 | MP0009765_abnormal_xenobiotic_induced | 0.64879432 |
| 95 | MP0003448_altered_tumor_morphology | 0.64843756 |
| 96 | MP0001666_abnormal_nutrient_absorption | 0.64672622 |
| 97 | MP0005166_decreased_susceptibility_to | 0.64331566 |
| 98 | MP0005360_urolithiasis | 0.64201186 |
| 99 | MP0001756_abnormal_urination | 0.64139436 |
| 100 | MP0010329_abnormal_lipoprotein_level | 0.64115880 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Meningioma (HP:0002858) | 5.84400487 |
| 2 | Methylmalonic aciduria (HP:0012120) | 5.19769744 |
| 3 | Hyperglycinemia (HP:0002154) | 4.98436032 |
| 4 | Methylmalonic acidemia (HP:0002912) | 4.68110619 |
| 5 | Aplastic anemia (HP:0001915) | 4.07073989 |
| 6 | Increased intramyocellular lipid droplets (HP:0012240) | 3.57848019 |
| 7 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 3.54657423 |
| 8 | Dicarboxylic aciduria (HP:0003215) | 3.54657423 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.41809139 |
| 10 | Acute necrotizing encephalopathy (HP:0006965) | 3.35777346 |
| 11 | Melanoma (HP:0002861) | 3.34764366 |
| 12 | Mitochondrial inheritance (HP:0001427) | 3.33547315 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.29831464 |
| 14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.20645862 |
| 15 | Pancytopenia (HP:0001876) | 3.18235514 |
| 16 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 3.11240380 |
| 17 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.10425813 |
| 18 | Increased muscle lipid content (HP:0009058) | 3.06995264 |
| 19 | Increased CSF lactate (HP:0002490) | 3.02469729 |
| 20 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.01745118 |
| 21 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.01745118 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 2.99162808 |
| 23 | Neoplasm of the lung (HP:0100526) | 2.98169148 |
| 24 | Stomatitis (HP:0010280) | 2.96125035 |
| 25 | Increased hepatocellular lipid droplets (HP:0006565) | 2.95564083 |
| 26 | Abnormality of vitamin B metabolism (HP:0004340) | 2.92902280 |
| 27 | Acute encephalopathy (HP:0006846) | 2.88688639 |
| 28 | Abnormality of glycine metabolism (HP:0010895) | 2.86171664 |
| 29 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.86171664 |
| 30 | Neoplasm of the respiratory system (HP:0100606) | 2.83446161 |
| 31 | Hepatocellular necrosis (HP:0001404) | 2.73992844 |
| 32 | Increased IgM level (HP:0003496) | 2.73122949 |
| 33 | Lipid accumulation in hepatocytes (HP:0006561) | 2.68999177 |
| 34 | Confusion (HP:0001289) | 2.67462197 |
| 35 | Ketosis (HP:0001946) | 2.67269089 |
| 36 | Increased serum lactate (HP:0002151) | 2.64784589 |
| 37 | Benign neoplasm of the central nervous system (HP:0100835) | 2.63770304 |
| 38 | Hepatic necrosis (HP:0002605) | 2.63755191 |
| 39 | Hyperammonemia (HP:0001987) | 2.61985639 |
| 40 | Lethargy (HP:0001254) | 2.54632798 |
| 41 | Hypoplasia of the uterus (HP:0000013) | 2.49757937 |
| 42 | Lymphangioma (HP:0100764) | 2.48349699 |
| 43 | Lactic acidosis (HP:0003128) | 2.46449790 |
| 44 | Abnormality of serum amino acid levels (HP:0003112) | 2.44473903 |
| 45 | Type I transferrin isoform profile (HP:0003642) | 2.39952715 |
| 46 | Multiple enchondromatosis (HP:0005701) | 2.38088977 |
| 47 | Cerebral edema (HP:0002181) | 2.37805379 |
| 48 | Abnormality of urine glucose concentration (HP:0011016) | 2.35157879 |
| 49 | Glycosuria (HP:0003076) | 2.35157879 |
| 50 | 3-Methylglutaconic aciduria (HP:0003535) | 2.29505769 |
| 51 | Optic disc pallor (HP:0000543) | 2.25581147 |
| 52 | IgG deficiency (HP:0004315) | 2.25570884 |
| 53 | Reduced antithrombin III activity (HP:0001976) | 2.21039275 |
| 54 | Hypoproteinemia (HP:0003075) | 2.19539024 |
| 55 | Carpal bone hypoplasia (HP:0001498) | 2.18912528 |
| 56 | Metabolic acidosis (HP:0001942) | 2.18204053 |
| 57 | Generalized aminoaciduria (HP:0002909) | 2.15986703 |
| 58 | Abnormality of T cell number (HP:0011839) | 2.12676102 |
| 59 | T lymphocytopenia (HP:0005403) | 2.11991901 |
| 60 | Spastic paraparesis (HP:0002313) | 2.09668000 |
| 61 | Thyroiditis (HP:0100646) | 2.09406019 |
| 62 | Neoplasm of the adrenal gland (HP:0100631) | 2.09219432 |
| 63 | Respiratory distress (HP:0002098) | 2.09038953 |
| 64 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.08717553 |
| 65 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.07371031 |
| 66 | Conjunctival hamartoma (HP:0100780) | 2.06232302 |
| 67 | Agammaglobulinemia (HP:0004432) | 2.05270555 |
| 68 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.03309697 |
| 69 | Respiratory failure (HP:0002878) | 2.01830930 |
| 70 | Oral leukoplakia (HP:0002745) | 2.00955295 |
| 71 | Exertional dyspnea (HP:0002875) | 2.00025036 |
| 72 | Cutaneous melanoma (HP:0012056) | 12.1353014 |
| 73 | Abnormality of alanine metabolism (HP:0010916) | 1.99946127 |
| 74 | Hyperalaninemia (HP:0003348) | 1.99946127 |
| 75 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.99946127 |
| 76 | Congenital, generalized hypertrichosis (HP:0004540) | 1.99466123 |
| 77 | Attenuation of retinal blood vessels (HP:0007843) | 1.98423056 |
| 78 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.95267093 |
| 79 | Abnormality of vitamin metabolism (HP:0100508) | 1.93859889 |
| 80 | Exercise intolerance (HP:0003546) | 1.88522733 |
| 81 | Short femoral neck (HP:0100864) | 1.85647446 |
| 82 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.84054871 |
| 83 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.82407961 |
| 84 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.82407961 |
| 85 | Abnormal protein glycosylation (HP:0012346) | 1.82407961 |
| 86 | Abnormal glycosylation (HP:0012345) | 1.82407961 |
| 87 | Congenital stationary night blindness (HP:0007642) | 1.81042402 |
| 88 | Brushfield spots (HP:0001088) | 1.78579987 |
| 89 | Rhabdomyolysis (HP:0003201) | 1.76398174 |
| 90 | Abnormality of T cells (HP:0002843) | 1.75291743 |
| 91 | Respiratory difficulties (HP:0002880) | 1.75095463 |
| 92 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.74304261 |
| 93 | Severe global developmental delay (HP:0011344) | 1.72288099 |
| 94 | Ulnar deviation of the wrist (HP:0003049) | 1.71243689 |
| 95 | Enlarged penis (HP:0000040) | 1.68849349 |
| 96 | Abnormality of renal resorption (HP:0011038) | 1.68496043 |
| 97 | Abnormality of B cell number (HP:0010975) | 1.67651068 |
| 98 | Anxiety (HP:0000739) | 1.67376238 |
| 99 | Panhypogammaglobulinemia (HP:0003139) | 1.66292909 |
| 100 | Type 2 muscle fiber atrophy (HP:0003554) | 1.66057379 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 4.72644087 |
| 2 | BCKDK | 3.63528057 |
| 3 | MST4 | 3.40328029 |
| 4 | PBK | 3.25087636 |
| 5 | TAOK3 | 3.07775389 |
| 6 | VRK2 | 2.86911419 |
| 7 | MAP4K1 | 2.83304721 |
| 8 | STK16 | 2.64049601 |
| 9 | MAP3K13 | 2.63356750 |
| 10 | CDK19 | 2.61707405 |
| 11 | ZAK | 2.51804196 |
| 12 | KDR | 2.41061092 |
| 13 | TXK | 2.38951473 |
| 14 | NUAK1 | 2.20819176 |
| 15 | FGFR2 | 1.90833668 |
| 16 | TLK1 | 1.79440682 |
| 17 | MAP3K11 | 1.75165256 |
| 18 | VRK1 | 1.71495032 |
| 19 | MAPKAPK3 | 1.64861760 |
| 20 | WNK4 | 1.57675604 |
| 21 | ADRBK2 | 1.57086217 |
| 22 | EIF2AK3 | 1.53839866 |
| 23 | CDK3 | 1.40204887 |
| 24 | NLK | 1.39914737 |
| 25 | IKBKB | 1.38504885 |
| 26 | PRKCQ | 1.36898034 |
| 27 | NME1 | 1.28908172 |
| 28 | MAP3K14 | 1.28132502 |
| 29 | EIF2AK1 | 1.27551820 |
| 30 | NME2 | 1.17075448 |
| 31 | ITK | 1.15579010 |
| 32 | SCYL2 | 1.15100407 |
| 33 | PLK3 | 1.13962716 |
| 34 | CSNK1G1 | 1.13728331 |
| 35 | GRK1 | 1.12034092 |
| 36 | PINK1 | 1.09945788 |
| 37 | DYRK2 | 1.05044579 |
| 38 | MAPK7 | 0.97990791 |
| 39 | PASK | 0.95791118 |
| 40 | INSRR | 0.94109293 |
| 41 | PLK1 | 0.92397052 |
| 42 | TEC | 0.89713209 |
| 43 | EPHB2 | 0.83076668 |
| 44 | TSSK6 | 0.82584328 |
| 45 | AURKA | 0.78823725 |
| 46 | CDC7 | 0.75000854 |
| 47 | ABL2 | 0.74065098 |
| 48 | SYK | 0.72717615 |
| 49 | ACVR1B | 0.72420708 |
| 50 | DAPK1 | 0.68721603 |
| 51 | ADRBK1 | 0.68123272 |
| 52 | SGK2 | 0.66978244 |
| 53 | PIK3CG | 0.65887846 |
| 54 | RPS6KB2 | 0.65590407 |
| 55 | STK4 | 0.64149496 |
| 56 | BTK | 0.64016601 |
| 57 | PLK4 | 0.62213258 |
| 58 | PRKG2 | 0.62185495 |
| 59 | LCK | 0.60853781 |
| 60 | ILK | 0.60849901 |
| 61 | CSF1R | 0.59232263 |
| 62 | STK39 | 0.59230798 |
| 63 | FLT3 | 0.59065970 |
| 64 | ATR | 0.58750755 |
| 65 | CDK4 | 0.58020788 |
| 66 | TESK2 | 0.56507773 |
| 67 | IKBKE | 0.54475327 |
| 68 | CHUK | 0.54272274 |
| 69 | NEK2 | 0.53683814 |
| 70 | TIE1 | 0.53081505 |
| 71 | MAPKAPK5 | 0.52330355 |
| 72 | MAP3K5 | 0.51952945 |
| 73 | LYN | 0.50042241 |
| 74 | TAF1 | 0.48788572 |
| 75 | SGK223 | 0.48080563 |
| 76 | SGK494 | 0.48080563 |
| 77 | CSNK2A2 | 0.47540199 |
| 78 | KIT | 0.45540359 |
| 79 | TBK1 | 0.45035039 |
| 80 | MAP4K2 | 0.43843703 |
| 81 | MYLK | 0.43751908 |
| 82 | SGK1 | 0.42542813 |
| 83 | RPS6KA5 | 0.41854712 |
| 84 | MAP3K12 | 0.40355848 |
| 85 | CSK | 0.40302361 |
| 86 | OXSR1 | 0.40182467 |
| 87 | CSNK1A1 | 0.39624776 |
| 88 | CSNK2A1 | 0.39199197 |
| 89 | MAP2K6 | 0.38733287 |
| 90 | GRK6 | 0.36388624 |
| 91 | NEK1 | 0.33060720 |
| 92 | RPS6KA4 | 0.29677849 |
| 93 | CSNK1G3 | 0.29362579 |
| 94 | BMPR1B | 0.27952876 |
| 95 | DAPK3 | 0.27907976 |
| 96 | PRKCA | 0.26375574 |
| 97 | RPS6KB1 | 0.24961433 |
| 98 | OBSCN | 0.24941613 |
| 99 | PDK2 | 0.24683037 |
| 100 | MAPK15 | 0.24107885 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.54270119 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.30019041 |
| 3 | Sulfur metabolism_Homo sapiens_hsa00920 | 3.26098407 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.87310197 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.62469166 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.56226081 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.51876885 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.39845337 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.33977882 |
| 10 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 2.26687821 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.24890573 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.18611528 |
| 13 | Base excision repair_Homo sapiens_hsa03410 | 2.10546586 |
| 14 | DNA replication_Homo sapiens_hsa03030 | 2.06678227 |
| 15 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.95264420 |
| 16 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.89993054 |
| 17 | Peroxisome_Homo sapiens_hsa04146 | 1.85791499 |
| 18 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.83899288 |
| 19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.83077349 |
| 20 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.81917240 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.75478559 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.67871628 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.60838625 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.52725129 |
| 25 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.48399944 |
| 26 | Huntingtons disease_Homo sapiens_hsa05016 | 1.43416287 |
| 27 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.41548065 |
| 28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.33594349 |
| 29 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.32137371 |
| 30 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.30822027 |
| 31 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.25012485 |
| 32 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.24554706 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.24536396 |
| 34 | Alzheimers disease_Homo sapiens_hsa05010 | 1.23670676 |
| 35 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.23086562 |
| 36 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.22197209 |
| 37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19187571 |
| 38 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.15320693 |
| 39 | Sulfur relay system_Homo sapiens_hsa04122 | 1.12424082 |
| 40 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.09569172 |
| 41 | Mismatch repair_Homo sapiens_hsa03430 | 1.05618424 |
| 42 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.03542476 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.01595973 |
| 44 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.99639397 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.98724226 |
| 46 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.93207563 |
| 47 | Phototransduction_Homo sapiens_hsa04744 | 0.91925642 |
| 48 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.90941433 |
| 49 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.90088479 |
| 50 | Retinol metabolism_Homo sapiens_hsa00830 | 0.90041107 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89996749 |
| 52 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.89680078 |
| 53 | Basal transcription factors_Homo sapiens_hsa03022 | 0.87041178 |
| 54 | Spliceosome_Homo sapiens_hsa03040 | 0.85532865 |
| 55 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.84372800 |
| 56 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.79134880 |
| 57 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76739537 |
| 58 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.75462841 |
| 59 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.73160274 |
| 60 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.72261646 |
| 61 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.72060511 |
| 62 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.71784028 |
| 63 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.69349706 |
| 64 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.65636246 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65051026 |
| 66 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.63147495 |
| 67 | Measles_Homo sapiens_hsa05162 | 0.62407396 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62084794 |
| 69 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.60966817 |
| 70 | RNA transport_Homo sapiens_hsa03013 | 0.59400287 |
| 71 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.59223310 |
| 72 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.57353413 |
| 73 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.53635830 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.53366757 |
| 75 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.52491569 |
| 76 | Shigellosis_Homo sapiens_hsa05131 | 0.50143852 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50122763 |
| 78 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.48766063 |
| 79 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46543353 |
| 80 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45564072 |
| 81 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.43308806 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.42877869 |
| 83 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.41611150 |
| 84 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.40959853 |
| 85 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.39736148 |
| 86 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.38538550 |
| 87 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.38320188 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.37222258 |
| 89 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.36291415 |
| 90 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.35012382 |
| 91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.30208234 |
| 92 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.29776921 |
| 93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.29636249 |
| 94 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.28964108 |
| 95 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.28431395 |
| 96 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.27658938 |
| 97 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.25342630 |
| 98 | Insulin resistance_Homo sapiens_hsa04931 | 0.24322512 |
| 99 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.22907497 |
| 100 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.22217489 |

