

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.38050213 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 6.55191513 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.55191513 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.99870820 |
| 5 | viral transcription (GO:0019083) | 5.65824308 |
| 6 | maturation of SSU-rRNA (GO:0030490) | 5.64061056 |
| 7 | translational termination (GO:0006415) | 5.39030425 |
| 8 | ribosomal small subunit biogenesis (GO:0042274) | 5.30698839 |
| 9 | translational elongation (GO:0006414) | 4.80011567 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.79653866 |
| 11 | protein targeting to ER (GO:0045047) | 4.74104421 |
| 12 | cotranslational protein targeting to membrane (GO:0006613) | 4.71470549 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 4.51880398 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.48985352 |
| 15 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.38593456 |
| 16 | electron transport chain (GO:0022900) | 4.30155505 |
| 17 | viral life cycle (GO:0019058) | 4.23977395 |
| 18 | respiratory electron transport chain (GO:0022904) | 4.23312128 |
| 19 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.21421120 |
| 20 | cellular protein complex disassembly (GO:0043624) | 4.07853526 |
| 21 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.06945172 |
| 22 | response to pheromone (GO:0019236) | 4.06430301 |
| 23 | DNA deamination (GO:0045006) | 3.99689727 |
| 24 | translational initiation (GO:0006413) | 3.94430436 |
| 25 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.85917117 |
| 26 | chaperone-mediated protein transport (GO:0072321) | 3.74165792 |
| 27 | positive regulation of respiratory burst (GO:0060267) | 3.70373952 |
| 28 | protein complex biogenesis (GO:0070271) | 3.67964930 |
| 29 | behavioral response to nicotine (GO:0035095) | 3.67492017 |
| 30 | translation (GO:0006412) | 3.67190371 |
| 31 | ATP biosynthetic process (GO:0006754) | 3.63925241 |
| 32 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.60409756 |
| 33 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.59597611 |
| 34 | protein neddylation (GO:0045116) | 3.55770595 |
| 35 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.52810738 |
| 36 | NADH dehydrogenase complex assembly (GO:0010257) | 3.49139348 |
| 37 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.49139348 |
| 38 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.49139348 |
| 39 | ribosomal large subunit biogenesis (GO:0042273) | 3.47891358 |
| 40 | GTP biosynthetic process (GO:0006183) | 3.45893450 |
| 41 | hydrogen ion transmembrane transport (GO:1902600) | 3.40140378 |
| 42 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.35882191 |
| 43 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.35882191 |
| 44 | protein complex disassembly (GO:0043241) | 3.34174582 |
| 45 | regulation of guanylate cyclase activity (GO:0031282) | 3.33414116 |
| 46 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.28590011 |
| 47 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.28568952 |
| 48 | respiratory chain complex IV assembly (GO:0008535) | 3.24337870 |
| 49 | cytidine metabolic process (GO:0046087) | 3.23008556 |
| 50 | cytidine catabolic process (GO:0006216) | 3.23008556 |
| 51 | cytidine deamination (GO:0009972) | 3.23008556 |
| 52 | GDP-mannose metabolic process (GO:0019673) | 3.17653398 |
| 53 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.16069492 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.16069492 |
| 55 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.16069492 |
| 56 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.16016506 |
| 57 | proton transport (GO:0015992) | 3.15901295 |
| 58 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.15830675 |
| 59 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.15768128 |
| 60 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.15768128 |
| 61 | macromolecular complex disassembly (GO:0032984) | 3.15129501 |
| 62 | signal peptide processing (GO:0006465) | 3.14295948 |
| 63 | regulation of immunoglobulin secretion (GO:0051023) | 3.13357851 |
| 64 | proteasome assembly (GO:0043248) | 3.12586583 |
| 65 | pseudouridine synthesis (GO:0001522) | 3.09502604 |
| 66 | cellular component biogenesis (GO:0044085) | 3.09154570 |
| 67 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.08429518 |
| 68 | hydrogen transport (GO:0006818) | 3.06838140 |
| 69 | sulfation (GO:0051923) | 3.06607530 |
| 70 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.03333812 |
| 71 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.03333812 |
| 72 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.01141180 |
| 73 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.00139243 |
| 74 | protein targeting to membrane (GO:0006612) | 2.99668878 |
| 75 | UTP biosynthetic process (GO:0006228) | 2.99465133 |
| 76 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.98290268 |
| 77 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.97209759 |
| 78 | NADH metabolic process (GO:0006734) | 2.94094554 |
| 79 | rRNA modification (GO:0000154) | 2.89153163 |
| 80 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.88266605 |
| 81 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.87598362 |
| 82 | rRNA processing (GO:0006364) | 2.86590661 |
| 83 | UTP metabolic process (GO:0046051) | 2.84628399 |
| 84 | rRNA metabolic process (GO:0016072) | 2.83804979 |
| 85 | positive regulation of guanylate cyclase activity (GO:0031284) | 2.82947257 |
| 86 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.81188203 |
| 87 | mannosylation (GO:0097502) | 2.77571959 |
| 88 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.74889928 |
| 89 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.74206890 |
| 90 | cytochrome complex assembly (GO:0017004) | 2.73979573 |
| 91 | disruption of cells of other organism (GO:0044364) | 2.72904304 |
| 92 | killing of cells of other organism (GO:0031640) | 2.72904304 |
| 93 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.72308183 |
| 94 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.68342502 |
| 95 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.68231572 |
| 96 | negative regulation of ligase activity (GO:0051352) | 2.68231572 |
| 97 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.67012195 |
| 98 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.65083521 |
| 99 | establishment of protein localization to mitochondrion (GO:0072655) | 2.64866252 |
| 100 | tRNA processing (GO:0008033) | 2.64639568 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.43466271 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.69769326 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.62221062 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.59618969 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.40841983 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.29448522 |
| 7 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.28624564 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.09194858 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.96837032 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.94315869 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.70392045 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.52788350 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.37726396 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.36590219 |
| 15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.32550426 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.27159077 |
| 17 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.24040093 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.08139431 |
| 19 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.06390862 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.02896220 |
| 21 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.98991166 |
| 22 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.97008446 |
| 23 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.91732035 |
| 24 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.82222249 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.79125738 |
| 26 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.73095598 |
| 27 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.72059075 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.67543372 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.64220006 |
| 30 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.58554490 |
| 31 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.58291133 |
| 32 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.57958065 |
| 33 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.57566216 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.57186336 |
| 35 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.56934661 |
| 36 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.56439590 |
| 37 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.56356610 |
| 38 | EWS_26573619_Chip-Seq_HEK293_Human | 1.56090205 |
| 39 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.47600579 |
| 40 | ERA_21632823_ChIP-Seq_H3396_Human | 1.46971918 |
| 41 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.43955527 |
| 42 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.43955527 |
| 43 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.43596032 |
| 44 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35418751 |
| 45 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.29212606 |
| 46 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.28962405 |
| 47 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.28728670 |
| 48 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.28596261 |
| 49 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.23493105 |
| 50 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.23183514 |
| 51 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.19520922 |
| 52 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.18788878 |
| 53 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.18576212 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.17712839 |
| 55 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.15460553 |
| 56 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.14881220 |
| 57 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.14645569 |
| 58 | NCOR_22424771_ChIP-Seq_293T_Human | 1.14082520 |
| 59 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.13033200 |
| 60 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.11357376 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.10274470 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.10274470 |
| 63 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.09384199 |
| 64 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.09117645 |
| 65 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.07853092 |
| 66 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.03958686 |
| 67 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.03613666 |
| 68 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.03376043 |
| 69 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.02749419 |
| 70 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.02278357 |
| 71 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.01721924 |
| 72 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00565906 |
| 73 | SA1_27219007_Chip-Seq_Bcells_Human | 1.00486552 |
| 74 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00336934 |
| 75 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00315601 |
| 76 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.99534551 |
| 77 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99400781 |
| 78 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.98960808 |
| 79 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.97615566 |
| 80 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96352514 |
| 81 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96225913 |
| 82 | AR_20517297_ChIP-Seq_VCAP_Human | 0.95880316 |
| 83 | P300_27268052_Chip-Seq_Bcells_Human | 0.95460307 |
| 84 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.95047996 |
| 85 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.94986347 |
| 86 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.93748105 |
| 87 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.93558502 |
| 88 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.93214614 |
| 89 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.92900537 |
| 90 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.92497167 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.92367326 |
| 92 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.91762815 |
| 93 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.90883150 |
| 94 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.90594368 |
| 95 | FUS_26573619_Chip-Seq_HEK293_Human | 0.89599385 |
| 96 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.87611416 |
| 97 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.86725318 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.85389460 |
| 99 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.84913090 |
| 100 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.83652370 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.78858278 |
| 2 | MP0005360_urolithiasis | 3.21146838 |
| 3 | MP0008875_abnormal_xenobiotic_pharmacok | 2.96194850 |
| 4 | MP0005075_abnormal_melanosome_morpholog | 2.76378467 |
| 5 | MP0008872_abnormal_physiological_respon | 2.38799882 |
| 6 | MP0004147_increased_porphyrin_level | 2.32188410 |
| 7 | MP0002163_abnormal_gland_morphology | 2.28725730 |
| 8 | MP0005377_hearing/vestibular/ear_phenot | 2.15335291 |
| 9 | MP0003878_abnormal_ear_physiology | 2.15335291 |
| 10 | MP0002138_abnormal_hepatobiliary_system | 2.15243035 |
| 11 | MP0002102_abnormal_ear_morphology | 2.13708475 |
| 12 | MP0003718_maternal_effect | 2.09051258 |
| 13 | MP0003806_abnormal_nucleotide_metabolis | 2.07511972 |
| 14 | MP0001873_stomach_inflammation | 2.06733712 |
| 15 | MP0002938_white_spotting | 2.06116202 |
| 16 | MP0003646_muscle_fatigue | 2.01336020 |
| 17 | MP0005085_abnormal_gallbladder_physiolo | 2.00609138 |
| 18 | MP0003283_abnormal_digestive_organ | 1.96559660 |
| 19 | MP0002095_abnormal_skin_pigmentation | 1.93401859 |
| 20 | MP0001485_abnormal_pinna_reflex | 1.91956072 |
| 21 | MP0001666_abnormal_nutrient_absorption | 1.76081078 |
| 22 | MP0004019_abnormal_vitamin_homeostasis | 1.75846784 |
| 23 | MP0005084_abnormal_gallbladder_morpholo | 1.70510832 |
| 24 | MP0005671_abnormal_response_to | 1.68485621 |
| 25 | MP0005645_abnormal_hypothalamus_physiol | 1.67779970 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.66529655 |
| 27 | MP0004742_abnormal_vestibular_system | 1.66177480 |
| 28 | MP0003186_abnormal_redox_activity | 1.64076952 |
| 29 | MP0005387_immune_system_phenotype | 1.61999941 |
| 30 | MP0001790_abnormal_immune_system | 1.61999941 |
| 31 | MP0006292_abnormal_olfactory_placode | 1.60055369 |
| 32 | MP0003693_abnormal_embryo_hatching | 1.56395948 |
| 33 | MP0001986_abnormal_taste_sensitivity | 1.50947422 |
| 34 | MP0000015_abnormal_ear_pigmentation | 1.50394868 |
| 35 | MP0004145_abnormal_muscle_electrophysio | 1.47040548 |
| 36 | MP0005171_absent_coat_pigmentation | 1.42664820 |
| 37 | MP0001835_abnormal_antigen_presentation | 1.42569355 |
| 38 | MP0002160_abnormal_reproductive_system | 1.41436942 |
| 39 | MP0003136_yellow_coat_color | 1.34955832 |
| 40 | MP0001663_abnormal_digestive_system | 1.34801263 |
| 41 | MP0004885_abnormal_endolymph | 1.34685343 |
| 42 | MP0002139_abnormal_hepatobiliary_system | 1.32645805 |
| 43 | MP0001529_abnormal_vocalization | 1.30473196 |
| 44 | MP0002148_abnormal_hypersensitivity_rea | 1.27658738 |
| 45 | MP0004142_abnormal_muscle_tone | 1.26764511 |
| 46 | MP0002638_abnormal_pupillary_reflex | 1.25838413 |
| 47 | MP0010155_abnormal_intestine_physiology | 1.22065110 |
| 48 | MP0003866_abnormal_defecation | 1.18753650 |
| 49 | MP0000372_irregular_coat_pigmentation | 1.17577952 |
| 50 | MP0005636_abnormal_mineral_homeostasis | 1.16037330 |
| 51 | MP0004957_abnormal_blastocyst_morpholog | 1.15785709 |
| 52 | MP0005551_abnormal_eye_electrophysiolog | 1.14637714 |
| 53 | MP0005332_abnormal_amino_acid | 1.13208309 |
| 54 | MP0003183_abnormal_peptide_metabolism | 1.11339304 |
| 55 | MP0001440_abnormal_grooming_behavior | 1.11278204 |
| 56 | MP0004043_abnormal_pH_regulation | 1.10785002 |
| 57 | MP0001968_abnormal_touch/_nociception | 1.09928154 |
| 58 | MP0001324_abnormal_eye_pigmentation | 1.09173074 |
| 59 | MP0002876_abnormal_thyroid_physiology | 1.09147985 |
| 60 | MP0005389_reproductive_system_phenotype | 1.08705423 |
| 61 | MP0003195_calcinosis | 1.07786885 |
| 62 | MP0001764_abnormal_homeostasis | 1.07560016 |
| 63 | MP0009333_abnormal_splenocyte_physiolog | 1.05330868 |
| 64 | MP0002277_abnormal_respiratory_mucosa | 1.04183335 |
| 65 | MP0001293_anophthalmia | 1.03699277 |
| 66 | MP0000538_abnormal_urinary_bladder | 1.01398865 |
| 67 | MP0006036_abnormal_mitochondrial_physio | 1.00259789 |
| 68 | MP0005379_endocrine/exocrine_gland_phen | 0.98522951 |
| 69 | MP0001800_abnormal_humoral_immune | 0.98235289 |
| 70 | MP0001188_hyperpigmentation | 0.98009254 |
| 71 | MP0002653_abnormal_ependyma_morphology | 0.97814516 |
| 72 | MP0008058_abnormal_DNA_repair | 0.97545427 |
| 73 | MP0009785_altered_susceptibility_to | 0.96046293 |
| 74 | MP0002735_abnormal_chemical_nociception | 0.95515475 |
| 75 | MP0003786_premature_aging | 0.95401614 |
| 76 | MP0001919_abnormal_reproductive_system | 0.94224061 |
| 77 | MP0002736_abnormal_nociception_after | 0.93538760 |
| 78 | MP0005381_digestive/alimentary_phenotyp | 0.92785394 |
| 79 | MP0000490_abnormal_crypts_of | 0.91966697 |
| 80 | MP0009643_abnormal_urine_homeostasis | 0.91084434 |
| 81 | MP0008775_abnormal_heart_ventricle | 0.90717201 |
| 82 | MP0001664_abnormal_digestion | 0.89733358 |
| 83 | MP0002822_catalepsy | 0.89129315 |
| 84 | MP0001765_abnormal_ion_homeostasis | 0.85152895 |
| 85 | MP0001905_abnormal_dopamine_level | 0.83273283 |
| 86 | MP0005174_abnormal_tail_pigmentation | 0.83070630 |
| 87 | MP0005365_abnormal_bile_salt | 0.82794840 |
| 88 | MP0002272_abnormal_nervous_system | 0.82191421 |
| 89 | MP0003938_abnormal_ear_development | 0.78752450 |
| 90 | MP0004133_heterotaxia | 0.78440736 |
| 91 | MP0001756_abnormal_urination | 0.77820181 |
| 92 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77087782 |
| 93 | MP0000026_abnormal_inner_ear | 0.76888053 |
| 94 | MP0002733_abnormal_thermal_nociception | 0.75368309 |
| 95 | MP0001970_abnormal_pain_threshold | 0.71465904 |
| 96 | MP0000427_abnormal_hair_cycle | 0.70634602 |
| 97 | MP0006276_abnormal_autonomic_nervous | 0.70626534 |
| 98 | MP0003252_abnormal_bile_duct | 0.70444742 |
| 99 | MP0001348_abnormal_lacrimal_gland | 0.69835631 |
| 100 | MP0010386_abnormal_urinary_bladder | 0.68587009 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 5.49662639 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 5.19542354 |
| 3 | Reticulocytopenia (HP:0001896) | 4.84188063 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.78887450 |
| 5 | Renal Fanconi syndrome (HP:0001994) | 4.65575227 |
| 6 | Mitochondrial inheritance (HP:0001427) | 4.62134250 |
| 7 | Acute encephalopathy (HP:0006846) | 4.46603215 |
| 8 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.43837931 |
| 9 | Increased CSF lactate (HP:0002490) | 4.35630557 |
| 10 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.15987986 |
| 11 | Increased intramyocellular lipid droplets (HP:0012240) | 4.01933160 |
| 12 | Hepatocellular necrosis (HP:0001404) | 4.01381551 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.98988965 |
| 14 | Exertional dyspnea (HP:0002875) | 3.86986301 |
| 15 | Hepatic necrosis (HP:0002605) | 3.80991804 |
| 16 | Increased muscle lipid content (HP:0009058) | 3.58041303 |
| 17 | Hyperglycinemia (HP:0002154) | 3.50557129 |
| 18 | Abnormality of urine glucose concentration (HP:0011016) | 3.47331829 |
| 19 | Glycosuria (HP:0003076) | 3.47331829 |
| 20 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.36871153 |
| 21 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.28839253 |
| 22 | Hyperphosphaturia (HP:0003109) | 3.26908193 |
| 23 | Respiratory difficulties (HP:0002880) | 3.18216071 |
| 24 | Cerebral edema (HP:0002181) | 3.14074298 |
| 25 | Hyperglycinuria (HP:0003108) | 3.12452946 |
| 26 | Macrocytic anemia (HP:0001972) | 3.11401820 |
| 27 | Abnormality of renal resorption (HP:0011038) | 3.04702861 |
| 28 | Increased serum lactate (HP:0002151) | 2.92816696 |
| 29 | Pallor (HP:0000980) | 2.86113499 |
| 30 | Lethargy (HP:0001254) | 2.84810222 |
| 31 | Methylmalonic aciduria (HP:0012120) | 2.84619073 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.77659821 |
| 33 | Optic disc pallor (HP:0000543) | 2.76117864 |
| 34 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.72986755 |
| 35 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.72986755 |
| 36 | Abnormality of glycine metabolism (HP:0010895) | 2.71779666 |
| 37 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.71779666 |
| 38 | Abnormal hemoglobin (HP:0011902) | 2.67738348 |
| 39 | Pendular nystagmus (HP:0012043) | 2.66497824 |
| 40 | Congenital stationary night blindness (HP:0007642) | 2.64845166 |
| 41 | Absent thumb (HP:0009777) | 2.62999992 |
| 42 | Abnormal urine phosphate concentration (HP:0012599) | 2.57573532 |
| 43 | Lactic acidosis (HP:0003128) | 2.56392047 |
| 44 | Dicarboxylic aciduria (HP:0003215) | 2.50704880 |
| 45 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.50704880 |
| 46 | Methylmalonic acidemia (HP:0002912) | 2.50072281 |
| 47 | Pancreatic cysts (HP:0001737) | 2.49168336 |
| 48 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.47256182 |
| 49 | Exercise intolerance (HP:0003546) | 2.45860383 |
| 50 | Pancytopenia (HP:0001876) | 2.43898181 |
| 51 | Cleft eyelid (HP:0000625) | 2.39361473 |
| 52 | Pancreatic fibrosis (HP:0100732) | 2.36749158 |
| 53 | Leukodystrophy (HP:0002415) | 2.36324404 |
| 54 | Respiratory failure (HP:0002878) | 2.30046847 |
| 55 | Abnormality of vitamin B metabolism (HP:0004340) | 2.29104274 |
| 56 | Abnormality of serum amino acid levels (HP:0003112) | 2.27337032 |
| 57 | True hermaphroditism (HP:0010459) | 2.24758824 |
| 58 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.22011802 |
| 59 | Generalized aminoaciduria (HP:0002909) | 2.17531729 |
| 60 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.17113599 |
| 61 | Asplenia (HP:0001746) | 2.16636597 |
| 62 | Hypoplasia of the ulna (HP:0003022) | 2.06926591 |
| 63 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.05999157 |
| 64 | Congenital sensorineural hearing impairment (HP:0008527) | 2.04766215 |
| 65 | Degeneration of anterior horn cells (HP:0002398) | 2.04099756 |
| 66 | Abnormality of the anterior horn cell (HP:0006802) | 2.04099756 |
| 67 | Molar tooth sign on MRI (HP:0002419) | 2.03623866 |
| 68 | Abnormality of midbrain morphology (HP:0002418) | 2.03623866 |
| 69 | Anencephaly (HP:0002323) | 1.99615069 |
| 70 | Confusion (HP:0001289) | 1.99263757 |
| 71 | Hypoplasia of the radius (HP:0002984) | 1.98392896 |
| 72 | IgG deficiency (HP:0004315) | 1.96160860 |
| 73 | Type I transferrin isoform profile (HP:0003642) | 1.90825387 |
| 74 | 3-Methylglutaconic aciduria (HP:0003535) | 1.89899888 |
| 75 | Renal tubular dysfunction (HP:0000124) | 1.88618106 |
| 76 | Abnormality of homocysteine metabolism (HP:0010919) | 1.88476337 |
| 77 | Homocystinuria (HP:0002156) | 1.88476337 |
| 78 | Abolished electroretinogram (ERG) (HP:0000550) | 1.86980939 |
| 79 | Nausea (HP:0002018) | 1.85095137 |
| 80 | Abnormality of the renal cortex (HP:0011035) | 1.81047637 |
| 81 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 1.79991116 |
| 82 | Hypoplasia of the pons (HP:0012110) | 1.79417512 |
| 83 | Renal cortical cysts (HP:0000803) | 1.78677767 |
| 84 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.76015708 |
| 85 | Meckel diverticulum (HP:0002245) | 1.75026675 |
| 86 | Proximal tubulopathy (HP:0000114) | 1.74099135 |
| 87 | Forearm undergrowth (HP:0009821) | 1.73996518 |
| 88 | Increased IgM level (HP:0003496) | 1.69405480 |
| 89 | Abnormality of the labia minora (HP:0012880) | 1.69249307 |
| 90 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.68832514 |
| 91 | Short thumb (HP:0009778) | 1.67424452 |
| 92 | Abnormality of the ileum (HP:0001549) | 1.67029839 |
| 93 | Congenital, generalized hypertrichosis (HP:0004540) | 1.66745729 |
| 94 | Hypoalbuminemia (HP:0003073) | 1.66665591 |
| 95 | Abnormal albumin level (HP:0012116) | 1.66665591 |
| 96 | Vomiting (HP:0002013) | 1.65343712 |
| 97 | Alkalosis (HP:0001948) | 1.65315303 |
| 98 | Abnormality of vitamin metabolism (HP:0100508) | 1.64092896 |
| 99 | Central scotoma (HP:0000603) | 1.61872707 |
| 100 | Oral leukoplakia (HP:0002745) | 1.59896558 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 5.29019044 |
| 2 | ADRBK2 | 3.28608570 |
| 3 | MST4 | 2.77213559 |
| 4 | TXK | 2.75135562 |
| 5 | STK16 | 2.39070766 |
| 6 | MAP4K2 | 2.26632888 |
| 7 | NME1 | 2.25983578 |
| 8 | GRK1 | 2.18412963 |
| 9 | CDK19 | 2.12487294 |
| 10 | WNK4 | 2.11934734 |
| 11 | VRK1 | 1.92049942 |
| 12 | WNK3 | 1.91793565 |
| 13 | TLK1 | 1.89110508 |
| 14 | TAF1 | 1.88607041 |
| 15 | ACVR1B | 1.88389323 |
| 16 | PBK | 1.84338810 |
| 17 | FRK | 1.78499235 |
| 18 | PINK1 | 1.75462173 |
| 19 | TRIM28 | 1.74499313 |
| 20 | OXSR1 | 1.73255983 |
| 21 | TNIK | 1.72556145 |
| 22 | PASK | 1.70346798 |
| 23 | MAP2K6 | 1.65656755 |
| 24 | STK39 | 1.63894018 |
| 25 | NUAK1 | 1.58792064 |
| 26 | NEK1 | 1.58205694 |
| 27 | BCKDK | 1.56789502 |
| 28 | NEK2 | 1.55585799 |
| 29 | MAP4K1 | 1.53869710 |
| 30 | DYRK2 | 1.41830944 |
| 31 | BUB1 | 1.41095342 |
| 32 | EIF2AK1 | 1.37570425 |
| 33 | ZAK | 1.26326509 |
| 34 | LMTK2 | 1.21025746 |
| 35 | NME2 | 1.17789758 |
| 36 | MAP3K12 | 1.16166552 |
| 37 | PDK2 | 1.13542723 |
| 38 | ADRBK1 | 1.10385116 |
| 39 | WEE1 | 1.08412252 |
| 40 | PLK3 | 1.06815093 |
| 41 | TAOK3 | 1.06252986 |
| 42 | LRRK2 | 1.03738271 |
| 43 | SRPK1 | 1.02021544 |
| 44 | LIMK1 | 0.89705214 |
| 45 | TSSK6 | 0.89549274 |
| 46 | BMPR1B | 0.89161546 |
| 47 | MYLK | 0.88380965 |
| 48 | DAPK1 | 0.84792087 |
| 49 | KDR | 0.83050038 |
| 50 | ABL2 | 0.79733314 |
| 51 | IKBKB | 0.79702364 |
| 52 | ILK | 0.77064743 |
| 53 | TEC | 0.71882781 |
| 54 | STK4 | 0.71257460 |
| 55 | PLK1 | 0.70587973 |
| 56 | DAPK3 | 0.69890448 |
| 57 | PRKCG | 0.69825892 |
| 58 | ITK | 0.69802109 |
| 59 | SIK2 | 0.67582596 |
| 60 | INSRR | 0.66595162 |
| 61 | STK24 | 0.65144793 |
| 62 | GRK5 | 0.64506011 |
| 63 | CSNK2A2 | 0.61927176 |
| 64 | TGFBR1 | 0.61414292 |
| 65 | CSNK2A1 | 0.58216804 |
| 66 | PIK3CA | 0.57186396 |
| 67 | PRKCQ | 0.53044304 |
| 68 | PLK4 | 0.51843446 |
| 69 | AURKB | 0.51110604 |
| 70 | MAP2K7 | 0.50205144 |
| 71 | CCNB1 | 0.49130053 |
| 72 | PRKG2 | 0.48914681 |
| 73 | ATR | 0.48057336 |
| 74 | PRKCI | 0.47518854 |
| 75 | PRKACA | 0.47195221 |
| 76 | PHKG1 | 0.47018823 |
| 77 | PHKG2 | 0.47018823 |
| 78 | RPS6KA5 | 0.46729761 |
| 79 | GRK7 | 0.45157355 |
| 80 | TESK2 | 0.43012712 |
| 81 | PRKCH | 0.41701027 |
| 82 | EPHA2 | 0.41224178 |
| 83 | PRKCA | 0.41222510 |
| 84 | PLK2 | 0.41193841 |
| 85 | CDC7 | 0.41016668 |
| 86 | MAPKAPK5 | 0.39666535 |
| 87 | RPS6KB1 | 0.39073645 |
| 88 | PRKCD | 0.38395346 |
| 89 | SYK | 0.38239913 |
| 90 | TIE1 | 0.37943735 |
| 91 | MINK1 | 0.35928009 |
| 92 | CDK8 | 0.35121801 |
| 93 | RPS6KA6 | 0.34603370 |
| 94 | MKNK2 | 0.34582113 |
| 95 | PRKCE | 0.33732201 |
| 96 | EIF2AK3 | 0.33224061 |
| 97 | EIF2AK2 | 0.32296898 |
| 98 | MAPK13 | 0.31047688 |
| 99 | AURKA | 0.29887019 |
| 100 | MUSK | 0.29559692 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.39914071 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.84656261 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.74101274 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.07787994 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.59563324 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.15264654 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.12891699 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.08204011 |
| 9 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.05976760 |
| 10 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.99183017 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 1.94509269 |
| 12 | Allograft rejection_Homo sapiens_hsa05330 | 1.85208819 |
| 13 | Homologous recombination_Homo sapiens_hsa03440 | 1.77325397 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.73463724 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71955217 |
| 16 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.67070660 |
| 17 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.65799727 |
| 18 | DNA replication_Homo sapiens_hsa03030 | 1.63276989 |
| 19 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.62467860 |
| 20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.50073214 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.49511821 |
| 22 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.48645208 |
| 23 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.47056441 |
| 24 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.44126740 |
| 25 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.41088230 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.38912421 |
| 27 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.37593846 |
| 28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.37445343 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.35670236 |
| 30 | Peroxisome_Homo sapiens_hsa04146 | 1.34404913 |
| 31 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.33559131 |
| 32 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.30809830 |
| 33 | Base excision repair_Homo sapiens_hsa03410 | 1.25812609 |
| 34 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.22348036 |
| 35 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.20746147 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.15253251 |
| 37 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.15019851 |
| 38 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.09013122 |
| 39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.06737373 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.05091898 |
| 41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.03463072 |
| 42 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.02880393 |
| 43 | Purine metabolism_Homo sapiens_hsa00230 | 1.01216497 |
| 44 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.00091487 |
| 45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.96912457 |
| 46 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.95194703 |
| 47 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.94806049 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.94721545 |
| 49 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.94308699 |
| 50 | Mineral absorption_Homo sapiens_hsa04978 | 0.94001350 |
| 51 | Sulfur relay system_Homo sapiens_hsa04122 | 0.92986101 |
| 52 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.92519928 |
| 53 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.92169942 |
| 54 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.91451338 |
| 55 | RNA degradation_Homo sapiens_hsa03018 | 0.91411121 |
| 56 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.90096851 |
| 57 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.88435692 |
| 58 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.87932727 |
| 59 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85429469 |
| 60 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.85226132 |
| 61 | Metabolic pathways_Homo sapiens_hsa01100 | 0.81557405 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.81400139 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80835917 |
| 64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.80100833 |
| 65 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.79777860 |
| 66 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79259840 |
| 67 | Phototransduction_Homo sapiens_hsa04744 | 0.75077014 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.74468748 |
| 69 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.74436661 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.74251244 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.73519613 |
| 72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.70025232 |
| 73 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.69054198 |
| 74 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.67574063 |
| 75 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.67189514 |
| 76 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.67018769 |
| 77 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.66889339 |
| 78 | RNA transport_Homo sapiens_hsa03013 | 0.64360675 |
| 79 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.57866030 |
| 80 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.56961852 |
| 81 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.55984136 |
| 82 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.55888232 |
| 83 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.55480829 |
| 84 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.55478822 |
| 85 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.54948079 |
| 86 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.53555830 |
| 87 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.53298746 |
| 88 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.50880431 |
| 89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.49615575 |
| 90 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.49139343 |
| 91 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.48614757 |
| 92 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.46935497 |
| 93 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46895036 |
| 94 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46297325 |
| 95 | Spliceosome_Homo sapiens_hsa03040 | 0.44582470 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.42432280 |
| 97 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.41770332 |
| 98 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40369524 |
| 99 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.39001854 |
| 100 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.37147772 |

