

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 8.83369674 |
| 2 | viral transcription (GO:0019083) | 7.20468635 |
| 3 | translational termination (GO:0006415) | 7.03524128 |
| 4 | translational elongation (GO:0006414) | 6.17655217 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.85437520 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 5.76407410 |
| 7 | protein targeting to ER (GO:0045047) | 5.73950444 |
| 8 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.52757714 |
| 9 | ribosomal small subunit biogenesis (GO:0042274) | 5.50821031 |
| 10 | protein localization to endoplasmic reticulum (GO:0070972) | 5.41173565 |
| 11 | cellular protein complex disassembly (GO:0043624) | 5.37805593 |
| 12 | maturation of SSU-rRNA (GO:0030490) | 5.36829718 |
| 13 | viral life cycle (GO:0019058) | 5.17579625 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.11512727 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 4.88650832 |
| 16 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.88650832 |
| 17 | DNA deamination (GO:0045006) | 4.67077843 |
| 18 | protein complex disassembly (GO:0043241) | 4.58661957 |
| 19 | CTP metabolic process (GO:0046036) | 4.56565299 |
| 20 | CTP biosynthetic process (GO:0006241) | 4.56565299 |
| 21 | translational initiation (GO:0006413) | 4.51679016 |
| 22 | behavioral response to nicotine (GO:0035095) | 4.44284759 |
| 23 | protein neddylation (GO:0045116) | 4.42228387 |
| 24 | macromolecular complex disassembly (GO:0032984) | 4.38917567 |
| 25 | chaperone-mediated protein transport (GO:0072321) | 4.37015257 |
| 26 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.33601093 |
| 27 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 4.15444267 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.08793752 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.08793752 |
| 30 | protein complex biogenesis (GO:0070271) | 4.02568987 |
| 31 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.01797281 |
| 32 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.99225807 |
| 33 | NADH dehydrogenase complex assembly (GO:0010257) | 3.99225807 |
| 34 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.99225807 |
| 35 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.97778398 |
| 36 | translation (GO:0006412) | 3.97371583 |
| 37 | ribosomal large subunit biogenesis (GO:0042273) | 3.90897051 |
| 38 | protein targeting to membrane (GO:0006612) | 3.84509313 |
| 39 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.80390999 |
| 40 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.76942299 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.71227170 |
| 42 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.69754880 |
| 43 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.62373782 |
| 44 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.59493117 |
| 45 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.58942510 |
| 46 | nucleotide salvage (GO:0043173) | 3.58650089 |
| 47 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 3.55062676 |
| 48 | UMP biosynthetic process (GO:0006222) | 3.55062676 |
| 49 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 3.55062676 |
| 50 | UMP metabolic process (GO:0046049) | 3.55062676 |
| 51 | ncRNA 3-end processing (GO:0043628) | 3.49532932 |
| 52 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.41319627 |
| 53 | behavioral response to ethanol (GO:0048149) | 3.40505295 |
| 54 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 3.37131364 |
| 55 | mRNA catabolic process (GO:0006402) | 3.36656250 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.36563556 |
| 57 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 3.35007800 |
| 58 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 3.33227578 |
| 59 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.33153942 |
| 60 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 3.26355146 |
| 61 | GTP biosynthetic process (GO:0006183) | 3.20029891 |
| 62 | piRNA metabolic process (GO:0034587) | 3.17926928 |
| 63 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 3.15863517 |
| 64 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.14592574 |
| 65 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.14592574 |
| 66 | cellular component biogenesis (GO:0044085) | 3.12593406 |
| 67 | opioid receptor signaling pathway (GO:0038003) | 3.12242830 |
| 68 | respiratory electron transport chain (GO:0022904) | 3.06316680 |
| 69 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.06208865 |
| 70 | RNA catabolic process (GO:0006401) | 3.04619749 |
| 71 | electron transport chain (GO:0022900) | 3.04413523 |
| 72 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.01049904 |
| 73 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.00379653 |
| 74 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.98270305 |
| 75 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.98141137 |
| 76 | base-excision repair, AP site formation (GO:0006285) | 2.97768038 |
| 77 | epithelial cilium movement (GO:0003351) | 2.97193220 |
| 78 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.95821149 |
| 79 | ATP biosynthetic process (GO:0006754) | 2.94174314 |
| 80 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.91269618 |
| 81 | nucleoside salvage (GO:0043174) | 2.89807641 |
| 82 | pyrimidine ribonucleotide metabolic process (GO:0009218) | 2.88447291 |
| 83 | cell proliferation in forebrain (GO:0021846) | 2.82171575 |
| 84 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.81205467 |
| 85 | cytidine metabolic process (GO:0046087) | 2.77607031 |
| 86 | cytidine catabolic process (GO:0006216) | 2.77607031 |
| 87 | cytidine deamination (GO:0009972) | 2.77607031 |
| 88 | adult feeding behavior (GO:0008343) | 2.75742174 |
| 89 | glycerophospholipid catabolic process (GO:0046475) | 2.73925214 |
| 90 | UTP biosynthetic process (GO:0006228) | 2.73595803 |
| 91 | pyrimidine nucleotide biosynthetic process (GO:0006221) | 2.71161184 |
| 92 | kynurenine metabolic process (GO:0070189) | 2.70747398 |
| 93 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 2.70417242 |
| 94 | positive regulation of cAMP-mediated signaling (GO:0043950) | 2.68246476 |
| 95 | hydrogen ion transmembrane transport (GO:1902600) | 2.62876108 |
| 96 | protein polyglutamylation (GO:0018095) | 2.62009488 |
| 97 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.59976038 |
| 98 | UTP metabolic process (GO:0046051) | 2.59752727 |
| 99 | somite development (GO:0061053) | 2.59237677 |
| 100 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.56449584 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.50043309 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.43235598 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.19063990 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.94787790 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.63125967 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.61977181 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.41281354 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.39163155 |
| 9 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.37047460 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.23082435 |
| 11 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.13323647 |
| 12 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.10888224 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.07020726 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.04574582 |
| 15 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.86527255 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.79346564 |
| 17 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.77556717 |
| 18 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.75566868 |
| 19 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.73320167 |
| 20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.65967345 |
| 21 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.62056735 |
| 22 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.60042941 |
| 23 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.59120662 |
| 24 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.58588860 |
| 25 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.57033297 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.54334598 |
| 27 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.53697071 |
| 28 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.51051216 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.49277607 |
| 30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.48326457 |
| 31 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.47104531 |
| 32 | ERA_21632823_ChIP-Seq_H3396_Human | 1.45006923 |
| 33 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.43739554 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.43094898 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.41224224 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.39450041 |
| 37 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.39157677 |
| 38 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.38285943 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.37869762 |
| 40 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.35974007 |
| 41 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.34507477 |
| 42 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.33444602 |
| 43 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.31264055 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.31168284 |
| 45 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.30821072 |
| 46 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.28778708 |
| 47 | NCOR_22424771_ChIP-Seq_293T_Human | 1.27049201 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.26149680 |
| 49 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.25546379 |
| 50 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.23414295 |
| 51 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.23124932 |
| 52 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.22880835 |
| 53 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.21506171 |
| 54 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.19319255 |
| 55 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18551695 |
| 56 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18551695 |
| 57 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.18538597 |
| 58 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18418046 |
| 59 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.18058859 |
| 60 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.17860335 |
| 61 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.17818487 |
| 62 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.16977981 |
| 63 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.16733093 |
| 64 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.15951294 |
| 65 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.12985275 |
| 66 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.12985275 |
| 67 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.12589375 |
| 68 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.12353027 |
| 69 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.12080598 |
| 70 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.11455032 |
| 71 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.10955251 |
| 72 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.09728202 |
| 73 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06950145 |
| 74 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.06814059 |
| 75 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.06287795 |
| 76 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.06154381 |
| 77 | FUS_26573619_Chip-Seq_HEK293_Human | 1.05669184 |
| 78 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.05659110 |
| 79 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.04640051 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04375202 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04375202 |
| 82 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04334037 |
| 83 | P300_19829295_ChIP-Seq_ESCs_Human | 1.03933458 |
| 84 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.02907317 |
| 85 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.01932401 |
| 86 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.00545909 |
| 87 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00191837 |
| 88 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99355211 |
| 89 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.98274231 |
| 90 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.97681586 |
| 91 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.97618487 |
| 92 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.95897213 |
| 93 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.95077434 |
| 94 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.94068494 |
| 95 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.93986811 |
| 96 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.93851055 |
| 97 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.92857858 |
| 98 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.92306022 |
| 99 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.92016274 |
| 100 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.91783838 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.39102661 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.33369084 |
| 3 | MP0002163_abnormal_gland_morphology | 3.24235697 |
| 4 | MP0003787_abnormal_imprinting | 3.09479474 |
| 5 | MP0003646_muscle_fatigue | 2.82854452 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.76977608 |
| 7 | MP0002876_abnormal_thyroid_physiology | 2.37884675 |
| 8 | MP0003122_maternal_imprinting | 2.30239884 |
| 9 | MP0008789_abnormal_olfactory_epithelium | 2.21707739 |
| 10 | MP0008875_abnormal_xenobiotic_pharmacok | 2.09698405 |
| 11 | MP0005645_abnormal_hypothalamus_physiol | 2.02842302 |
| 12 | MP0001968_abnormal_touch/_nociception | 1.96483644 |
| 13 | MP0001348_abnormal_lacrimal_gland | 1.90848519 |
| 14 | MP0005379_endocrine/exocrine_gland_phen | 1.88206230 |
| 15 | MP0005377_hearing/vestibular/ear_phenot | 1.85480309 |
| 16 | MP0003878_abnormal_ear_physiology | 1.85480309 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.80883546 |
| 18 | MP0002653_abnormal_ependyma_morphology | 1.80853011 |
| 19 | MP0002102_abnormal_ear_morphology | 1.76691376 |
| 20 | MP0003123_paternal_imprinting | 1.75099300 |
| 21 | MP0004142_abnormal_muscle_tone | 1.74932077 |
| 22 | MP0004885_abnormal_endolymph | 1.71262523 |
| 23 | MP0003880_abnormal_central_pattern | 1.70977634 |
| 24 | MP0005646_abnormal_pituitary_gland | 1.67847485 |
| 25 | MP0001485_abnormal_pinna_reflex | 1.64546711 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.64024616 |
| 27 | MP0000049_abnormal_middle_ear | 1.62527978 |
| 28 | MP0008872_abnormal_physiological_respon | 1.61674627 |
| 29 | MP0003121_genomic_imprinting | 1.59943839 |
| 30 | MP0005394_taste/olfaction_phenotype | 1.59806407 |
| 31 | MP0005499_abnormal_olfactory_system | 1.59806407 |
| 32 | MP0005360_urolithiasis | 1.55963998 |
| 33 | MP0006072_abnormal_retinal_apoptosis | 1.55633041 |
| 34 | MP0001529_abnormal_vocalization | 1.54102340 |
| 35 | MP0002837_dystrophic_cardiac_calcinosis | 1.50280315 |
| 36 | MP0002272_abnormal_nervous_system | 1.42478255 |
| 37 | MP0001293_anophthalmia | 1.32008260 |
| 38 | MP0001986_abnormal_taste_sensitivity | 1.29542262 |
| 39 | MP0005084_abnormal_gallbladder_morpholo | 1.29234746 |
| 40 | MP0002234_abnormal_pharynx_morphology | 1.25984172 |
| 41 | MP0005389_reproductive_system_phenotype | 1.25742167 |
| 42 | MP0003567_abnormal_fetal_cardiomyocyte | 1.25061120 |
| 43 | MP0004742_abnormal_vestibular_system | 1.24635122 |
| 44 | MP0001905_abnormal_dopamine_level | 1.24148674 |
| 45 | MP0004147_increased_porphyrin_level | 1.22038313 |
| 46 | MP0002095_abnormal_skin_pigmentation | 1.20621581 |
| 47 | MP0000678_abnormal_parathyroid_gland | 1.20211485 |
| 48 | MP0002733_abnormal_thermal_nociception | 1.17860591 |
| 49 | MP0001919_abnormal_reproductive_system | 1.16120025 |
| 50 | MP0009745_abnormal_behavioral_response | 1.14512109 |
| 51 | MP0009764_decreased_sensitivity_to | 1.12923678 |
| 52 | MP0004145_abnormal_muscle_electrophysio | 1.12157497 |
| 53 | MP0002138_abnormal_hepatobiliary_system | 1.08467452 |
| 54 | MP0002938_white_spotting | 1.07971290 |
| 55 | MP0002557_abnormal_social/conspecific_i | 1.07844408 |
| 56 | MP0008775_abnormal_heart_ventricle | 1.07493055 |
| 57 | MP0001970_abnormal_pain_threshold | 1.07183112 |
| 58 | MP0002160_abnormal_reproductive_system | 1.06746587 |
| 59 | MP0005195_abnormal_posterior_eye | 1.05000657 |
| 60 | MP0002736_abnormal_nociception_after | 1.02887969 |
| 61 | MP0003195_calcinosis | 1.00691870 |
| 62 | MP0003879_abnormal_hair_cell | 0.98806119 |
| 63 | MP0008058_abnormal_DNA_repair | 0.98177754 |
| 64 | MP0003183_abnormal_peptide_metabolism | 0.96587820 |
| 65 | MP0004133_heterotaxia | 0.94833295 |
| 66 | MP0001501_abnormal_sleep_pattern | 0.90075298 |
| 67 | MP0002752_abnormal_somatic_nervous | 0.90007260 |
| 68 | MP0000631_abnormal_neuroendocrine_gland | 0.89513144 |
| 69 | MP0000026_abnormal_inner_ear | 0.88485093 |
| 70 | MP0000778_abnormal_nervous_system | 0.88268645 |
| 71 | MP0005671_abnormal_response_to | 0.88053669 |
| 72 | MP0001440_abnormal_grooming_behavior | 0.84092484 |
| 73 | MP0002638_abnormal_pupillary_reflex | 0.82686090 |
| 74 | MP0005423_abnormal_somatic_nervous | 0.82332489 |
| 75 | MP0009046_muscle_twitch | 0.82103940 |
| 76 | MP0000230_abnormal_systemic_arterial | 0.80489681 |
| 77 | MP0001963_abnormal_hearing_physiology | 0.80482849 |
| 78 | MP0001664_abnormal_digestion | 0.79908084 |
| 79 | MP0003186_abnormal_redox_activity | 0.79501646 |
| 80 | MP0005253_abnormal_eye_physiology | 0.79396477 |
| 81 | MP0001764_abnormal_homeostasis | 0.79364340 |
| 82 | MP0002210_abnormal_sex_determination | 0.79101118 |
| 83 | MP0001486_abnormal_startle_reflex | 0.76365528 |
| 84 | MP0003937_abnormal_limbs/digits/tail_de | 0.75590021 |
| 85 | MP0003011_delayed_dark_adaptation | 0.75579765 |
| 86 | MP0002184_abnormal_innervation | 0.75560866 |
| 87 | MP0002572_abnormal_emotion/affect_behav | 0.75280872 |
| 88 | MP0003119_abnormal_digestive_system | 0.71783011 |
| 89 | MP0001984_abnormal_olfaction | 0.70110827 |
| 90 | MP0009278_abnormal_bone_marrow | 0.70098736 |
| 91 | MP0001663_abnormal_digestive_system | 0.69922943 |
| 92 | MP0001873_stomach_inflammation | 0.69662742 |
| 93 | MP0003635_abnormal_synaptic_transmissio | 0.69397867 |
| 94 | MP0006035_abnormal_mitochondrial_morpho | 0.69259119 |
| 95 | MP0002693_abnormal_pancreas_physiology | 0.68865935 |
| 96 | MP0000538_abnormal_urinary_bladder | 0.67754337 |
| 97 | MP0002735_abnormal_chemical_nociception | 0.67620591 |
| 98 | MP0009333_abnormal_splenocyte_physiolog | 0.67505632 |
| 99 | MP0004043_abnormal_pH_regulation | 0.66508568 |
| 100 | MP0005332_abnormal_amino_acid | 0.66486691 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.44230526 |
| 2 | Reticulocytopenia (HP:0001896) | 4.13683558 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.91736538 |
| 4 | Acute encephalopathy (HP:0006846) | 3.88123124 |
| 5 | Thyroid-stimulating hormone excess (HP:0002925) | 3.85806391 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.79064606 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.67879782 |
| 8 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.65879032 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.52064647 |
| 10 | Pancreatic fibrosis (HP:0100732) | 3.46633823 |
| 11 | Increased CSF lactate (HP:0002490) | 3.40521439 |
| 12 | Macrocytic anemia (HP:0001972) | 3.34804855 |
| 13 | Abnormality of midbrain morphology (HP:0002418) | 3.32605557 |
| 14 | Molar tooth sign on MRI (HP:0002419) | 3.32605557 |
| 15 | Abnormal number of erythroid precursors (HP:0012131) | 3.28745430 |
| 16 | Increased hepatocellular lipid droplets (HP:0006565) | 3.03301896 |
| 17 | Hyperglycinemia (HP:0002154) | 2.98987199 |
| 18 | Pancreatic cysts (HP:0001737) | 2.96965598 |
| 19 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.91002059 |
| 20 | Lipid accumulation in hepatocytes (HP:0006561) | 2.90696775 |
| 21 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.90581780 |
| 22 | Cerebral edema (HP:0002181) | 2.87459856 |
| 23 | Asplenia (HP:0001746) | 2.85257953 |
| 24 | Pallor (HP:0000980) | 2.84978525 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 2.67196777 |
| 26 | True hermaphroditism (HP:0010459) | 2.65282294 |
| 27 | Hepatocellular necrosis (HP:0001404) | 2.63260543 |
| 28 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.61484628 |
| 29 | Absent/shortened dynein arms (HP:0200106) | 2.59381632 |
| 30 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.59381632 |
| 31 | Optic disc pallor (HP:0000543) | 2.57515292 |
| 32 | Intestinal atresia (HP:0011100) | 2.57074016 |
| 33 | Agitation (HP:0000713) | 2.53760737 |
| 34 | Medial flaring of the eyebrow (HP:0010747) | 2.51471764 |
| 35 | Pendular nystagmus (HP:0012043) | 2.50806093 |
| 36 | Rib fusion (HP:0000902) | 2.48020673 |
| 37 | Nephronophthisis (HP:0000090) | 2.46227518 |
| 38 | Colon cancer (HP:0003003) | 2.45529381 |
| 39 | Congenital stationary night blindness (HP:0007642) | 2.44630316 |
| 40 | Tubular atrophy (HP:0000092) | 2.44005871 |
| 41 | Supernumerary spleens (HP:0009799) | 2.41686741 |
| 42 | Renal Fanconi syndrome (HP:0001994) | 2.41106198 |
| 43 | Hepatic necrosis (HP:0002605) | 2.40526910 |
| 44 | Sclerocornea (HP:0000647) | 2.40524530 |
| 45 | Hip dysplasia (HP:0001385) | 2.39464553 |
| 46 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.29544117 |
| 47 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.29544117 |
| 48 | Abnormality of DNA repair (HP:0003254) | 2.25126500 |
| 49 | Hyperthyroidism (HP:0000836) | 2.22739493 |
| 50 | Abnormal hemoglobin (HP:0011902) | 2.22185937 |
| 51 | Abnormal ciliary motility (HP:0012262) | 2.21970176 |
| 52 | Abolished electroretinogram (ERG) (HP:0000550) | 2.18870048 |
| 53 | Type II lissencephaly (HP:0007260) | 2.18284219 |
| 54 | Abnormality of the renal medulla (HP:0100957) | 2.14019181 |
| 55 | Absent thumb (HP:0009777) | 2.12962452 |
| 56 | Methylmalonic acidemia (HP:0002912) | 2.11184785 |
| 57 | Cystic liver disease (HP:0006706) | 2.11163730 |
| 58 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.10333745 |
| 59 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.09586794 |
| 60 | Increased intramyocellular lipid droplets (HP:0012240) | 2.09084008 |
| 61 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.08783416 |
| 62 | Increased serum lactate (HP:0002151) | 2.08595853 |
| 63 | Gait imbalance (HP:0002141) | 2.00203368 |
| 64 | Abnormality of the metopic suture (HP:0005556) | 2.00080845 |
| 65 | Polydipsia (HP:0001959) | 1.99095328 |
| 66 | Abnormal drinking behavior (HP:0030082) | 1.99095328 |
| 67 | Congenital primary aphakia (HP:0007707) | 1.97143743 |
| 68 | Abnormal biliary tract physiology (HP:0012439) | 1.96495201 |
| 69 | Bile duct proliferation (HP:0001408) | 1.96495201 |
| 70 | Prominent metopic ridge (HP:0005487) | 1.96206895 |
| 71 | Methylmalonic aciduria (HP:0012120) | 1.94061734 |
| 72 | Exertional dyspnea (HP:0002875) | 1.93882241 |
| 73 | Anencephaly (HP:0002323) | 1.92238831 |
| 74 | Polyuria (HP:0000103) | 1.89938271 |
| 75 | Metaphyseal dysplasia (HP:0100255) | 1.89697371 |
| 76 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.89668400 |
| 77 | Lactic acidosis (HP:0003128) | 1.87032907 |
| 78 | Optic nerve hypoplasia (HP:0000609) | 1.87029542 |
| 79 | Postaxial foot polydactyly (HP:0001830) | 1.86238630 |
| 80 | Abnormality of the renal cortex (HP:0011035) | 1.85075450 |
| 81 | Nephrogenic diabetes insipidus (HP:0009806) | 1.85022882 |
| 82 | Depressed nasal ridge (HP:0000457) | 1.84892075 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.84579924 |
| 84 | Type 2 muscle fiber atrophy (HP:0003554) | 1.84399067 |
| 85 | Broad alveolar ridges (HP:0000187) | 1.84332739 |
| 86 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.83752567 |
| 87 | Lethargy (HP:0001254) | 1.83221192 |
| 88 | Abnormality of the aortic arch (HP:0012303) | 1.81460371 |
| 89 | Constricted visual fields (HP:0001133) | 1.81190557 |
| 90 | Septo-optic dysplasia (HP:0100842) | 1.79504343 |
| 91 | Increased muscle lipid content (HP:0009058) | 1.79418047 |
| 92 | Hypomagnesemia (HP:0002917) | 1.77059358 |
| 93 | Anophthalmia (HP:0000528) | 1.76292790 |
| 94 | Stenosis of the external auditory canal (HP:0000402) | 1.74947181 |
| 95 | Respiratory failure (HP:0002878) | 1.74830228 |
| 96 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.73862971 |
| 97 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.73682228 |
| 98 | Increased corneal curvature (HP:0100692) | 1.73304795 |
| 99 | Keratoconus (HP:0000563) | 1.73304795 |
| 100 | Hypoplasia of the radius (HP:0002984) | 1.72452343 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 4.71514518 |
| 2 | MAP4K2 | 4.70139102 |
| 3 | FRK | 2.65205721 |
| 4 | STK16 | 2.63914574 |
| 5 | GRK1 | 2.62027049 |
| 6 | BMPR1B | 2.50032306 |
| 7 | CDK19 | 2.35702731 |
| 8 | BCKDK | 2.33815785 |
| 9 | TIE1 | 2.17794804 |
| 10 | VRK2 | 2.15302139 |
| 11 | WNK4 | 2.09296444 |
| 12 | LIMK1 | 2.09261391 |
| 13 | DYRK2 | 2.07266263 |
| 14 | PINK1 | 1.97692290 |
| 15 | NUAK1 | 1.94604247 |
| 16 | TLK1 | 1.82131038 |
| 17 | ZAK | 1.81074293 |
| 18 | PRKCG | 1.57152623 |
| 19 | TXK | 1.53042741 |
| 20 | ADRBK1 | 1.44216588 |
| 21 | WNK3 | 1.37995275 |
| 22 | PASK | 1.22972931 |
| 23 | INSRR | 1.19486738 |
| 24 | TGFBR1 | 1.17661596 |
| 25 | MAP4K1 | 1.14589433 |
| 26 | PIK3CA | 1.10626558 |
| 27 | TAOK3 | 1.09150178 |
| 28 | VRK1 | 1.04684300 |
| 29 | EPHB2 | 0.95811868 |
| 30 | CAMK1 | 0.93367401 |
| 31 | ACVR1B | 0.92711723 |
| 32 | MAP3K11 | 0.92138124 |
| 33 | STK39 | 0.92006716 |
| 34 | MUSK | 0.91824430 |
| 35 | TAF1 | 0.91334512 |
| 36 | LRRK2 | 0.90840740 |
| 37 | KDR | 0.88564819 |
| 38 | TEC | 0.86775974 |
| 39 | PRKCQ | 0.85260733 |
| 40 | OXSR1 | 0.83797204 |
| 41 | AURKA | 0.82348625 |
| 42 | CSNK2A2 | 0.82199220 |
| 43 | MAP3K12 | 0.81790578 |
| 44 | CDC7 | 0.81398685 |
| 45 | CSNK1G1 | 0.80870447 |
| 46 | DYRK3 | 0.78089684 |
| 47 | MAP2K7 | 0.75327609 |
| 48 | ITK | 0.74552713 |
| 49 | DAPK3 | 0.74003155 |
| 50 | FLT3 | 0.68396465 |
| 51 | PLK2 | 0.68004030 |
| 52 | EPHA4 | 0.66324738 |
| 53 | CSNK1G3 | 0.66301033 |
| 54 | CAMKK2 | 0.65864509 |
| 55 | PRKACA | 0.65323664 |
| 56 | STK11 | 0.65095439 |
| 57 | PRKCE | 0.63723791 |
| 58 | PLK1 | 0.62084560 |
| 59 | PRKCI | 0.61998569 |
| 60 | NEK1 | 0.60510957 |
| 61 | PRKCH | 0.60073234 |
| 62 | AURKB | 0.59946149 |
| 63 | MINK1 | 0.59435335 |
| 64 | CSNK2A1 | 0.59117539 |
| 65 | CSNK1G2 | 0.58796509 |
| 66 | CSNK1A1 | 0.57499732 |
| 67 | BTK | 0.57274474 |
| 68 | PRKCA | 0.56751141 |
| 69 | TYRO3 | 0.56378148 |
| 70 | MAPK13 | 0.55844291 |
| 71 | MKNK2 | 0.55547061 |
| 72 | MKNK1 | 0.55367356 |
| 73 | RPS6KA5 | 0.55058219 |
| 74 | PRKD3 | 0.55033998 |
| 75 | PLK4 | 0.52520504 |
| 76 | OBSCN | 0.51832316 |
| 77 | CAMK2A | 0.50980931 |
| 78 | NME2 | 0.49571049 |
| 79 | TNIK | 0.49423714 |
| 80 | IKBKB | 0.49232355 |
| 81 | NTRK2 | 0.48809565 |
| 82 | NME1 | 0.47525483 |
| 83 | MAP3K4 | 0.46538955 |
| 84 | GRK5 | 0.45679844 |
| 85 | KIT | 0.44890046 |
| 86 | PDK2 | 0.44757718 |
| 87 | MYLK | 0.44622744 |
| 88 | CSF1R | 0.43541067 |
| 89 | CSNK1E | 0.43009254 |
| 90 | CSNK1A1L | 0.42362206 |
| 91 | PRKCD | 0.41102874 |
| 92 | CHEK2 | 0.39091184 |
| 93 | CAMK4 | 0.38941524 |
| 94 | LCK | 0.38472854 |
| 95 | RPS6KA6 | 0.37892969 |
| 96 | ATR | 0.36823687 |
| 97 | GRK7 | 0.36707265 |
| 98 | DYRK1A | 0.35804426 |
| 99 | ABL2 | 0.35285208 |
| 100 | PRKACG | 0.34442892 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.10197877 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.61050159 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 2.97436369 |
| 4 | Sulfur relay system_Homo sapiens_hsa04122 | 2.77863798 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.49255078 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.30209656 |
| 7 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.19408505 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.16083376 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.09374941 |
| 10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.05264083 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 1.99762056 |
| 12 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.91175132 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 1.86612186 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.76201030 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.75611555 |
| 16 | Proteasome_Homo sapiens_hsa03050 | 1.72915552 |
| 17 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.70286340 |
| 18 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.65759458 |
| 19 | Protein export_Homo sapiens_hsa03060 | 1.59364904 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.43275688 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.40039496 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.29104796 |
| 23 | Asthma_Homo sapiens_hsa05310 | 1.29090294 |
| 24 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.28473181 |
| 25 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.27263328 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.25214106 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.21620067 |
| 28 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.21137784 |
| 29 | Base excision repair_Homo sapiens_hsa03410 | 1.19481466 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.13594175 |
| 31 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.13171270 |
| 32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.12398138 |
| 33 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.12031626 |
| 34 | Nicotine addiction_Homo sapiens_hsa05033 | 1.10385890 |
| 35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.07967395 |
| 36 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.06874731 |
| 37 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.05099240 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.04290876 |
| 39 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.03723744 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.03363237 |
| 41 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.03099169 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 1.02369066 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.00854249 |
| 44 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.00468863 |
| 45 | Olfactory transduction_Homo sapiens_hsa04740 | 0.97411806 |
| 46 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.91140947 |
| 47 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.89566874 |
| 48 | DNA replication_Homo sapiens_hsa03030 | 0.89212396 |
| 49 | Metabolic pathways_Homo sapiens_hsa01100 | 0.88088211 |
| 50 | Allograft rejection_Homo sapiens_hsa05330 | 0.87934984 |
| 51 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.86508026 |
| 52 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.86325253 |
| 53 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.86200974 |
| 54 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.84984955 |
| 55 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.84167201 |
| 56 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.81686985 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.81171637 |
| 58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.79418996 |
| 59 | Morphine addiction_Homo sapiens_hsa05032 | 0.79306658 |
| 60 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.77854788 |
| 61 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.76898491 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.76612369 |
| 63 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.75732742 |
| 64 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.72687494 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69780032 |
| 66 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.69074412 |
| 67 | Mismatch repair_Homo sapiens_hsa03430 | 0.66777318 |
| 68 | RNA transport_Homo sapiens_hsa03013 | 0.65999407 |
| 69 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.65495081 |
| 70 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.64975673 |
| 71 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.64195934 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63300860 |
| 73 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.60539338 |
| 74 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.59697924 |
| 75 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.58920140 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53710695 |
| 77 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.53594521 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.53428779 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.52641059 |
| 80 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.52244011 |
| 81 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.51022471 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.48588957 |
| 83 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.45342655 |
| 84 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43897807 |
| 85 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.43419567 |
| 86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.41377270 |
| 87 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.39993527 |
| 88 | Taste transduction_Homo sapiens_hsa04742 | 0.38859518 |
| 89 | Salivary secretion_Homo sapiens_hsa04970 | 0.38251976 |
| 90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.37975469 |
| 91 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.36250498 |
| 92 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.35822562 |
| 93 | Insulin secretion_Homo sapiens_hsa04911 | 0.34984445 |
| 94 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.34026937 |
| 95 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.32401606 |
| 96 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.30983029 |
| 97 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.29297839 |
| 98 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.28376241 |
| 99 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.28154233 |
| 100 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.28145397 |

