

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | behavioral response to nicotine (GO:0035095) | 6.62474900 |
| 2 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 6.38438460 |
| 3 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 5.80986786 |
| 4 | membrane repolarization during action potential (GO:0086011) | 5.44175950 |
| 5 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 5.02480321 |
| 6 | NADH dehydrogenase complex assembly (GO:0010257) | 5.02480321 |
| 7 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 5.02480321 |
| 8 | protein complex biogenesis (GO:0070271) | 4.88335886 |
| 9 | sulfation (GO:0051923) | 4.84215636 |
| 10 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.70775107 |
| 11 | cell proliferation in forebrain (GO:0021846) | 4.49920876 |
| 12 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.37480165 |
| 13 | regulation of DNA endoreduplication (GO:0032875) | 4.16797503 |
| 14 | regulation of membrane repolarization (GO:0060306) | 4.09001706 |
| 15 | serotonin metabolic process (GO:0042428) | 4.07316870 |
| 16 | positive regulation of synapse maturation (GO:0090129) | 4.06306177 |
| 17 | magnesium ion transport (GO:0015693) | 4.02576286 |
| 18 | membrane repolarization (GO:0086009) | 3.95780629 |
| 19 | primary amino compound metabolic process (GO:1901160) | 3.75733141 |
| 20 | regulation of mesoderm development (GO:2000380) | 3.75014614 |
| 21 | negative regulation of membrane potential (GO:0045837) | 3.72472428 |
| 22 | ovulation cycle (GO:0042698) | 3.72379595 |
| 23 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 3.67682646 |
| 24 | regulation of synapse maturation (GO:0090128) | 3.64001747 |
| 25 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.57486161 |
| 26 | regulation of skeletal muscle contraction (GO:0014819) | 3.52999621 |
| 27 | parturition (GO:0007567) | 3.52700583 |
| 28 | negative regulation of appetite (GO:0032099) | 3.48711597 |
| 29 | negative regulation of response to food (GO:0032096) | 3.48711597 |
| 30 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.46591918 |
| 31 | cellular response to exogenous dsRNA (GO:0071360) | 3.45300173 |
| 32 | protein polyglutamylation (GO:0018095) | 3.36300766 |
| 33 | indolalkylamine metabolic process (GO:0006586) | 3.34080353 |
| 34 | gamma-aminobutyric acid transport (GO:0015812) | 3.33943575 |
| 35 | negative regulation of systemic arterial blood pressure (GO:0003085) | 3.33355589 |
| 36 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 3.31722008 |
| 37 | positive regulation of endothelial cell differentiation (GO:0045603) | 3.31491201 |
| 38 | cellular potassium ion homeostasis (GO:0030007) | 3.29057611 |
| 39 | somite development (GO:0061053) | 3.28638025 |
| 40 | cellular response to electrical stimulus (GO:0071257) | 3.27895266 |
| 41 | retinal ganglion cell axon guidance (GO:0031290) | 3.26062229 |
| 42 | membrane depolarization during action potential (GO:0086010) | 3.24871762 |
| 43 | dentate gyrus development (GO:0021542) | 3.23478793 |
| 44 | positive regulation of fatty acid oxidation (GO:0046321) | 3.20753755 |
| 45 | regulation of potassium ion transmembrane transport (GO:1901379) | 3.16386477 |
| 46 | DNA deamination (GO:0045006) | 3.14559249 |
| 47 | cardiovascular system development (GO:0072358) | 3.13487009 |
| 48 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 3.11680263 |
| 49 | regulation of glomerulus development (GO:0090192) | 3.11134488 |
| 50 | response to xenobiotic stimulus (GO:0009410) | 3.08906103 |
| 51 | protein neddylation (GO:0045116) | 3.08870782 |
| 52 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.06188652 |
| 53 | vitamin A metabolic process (GO:0006776) | 3.04637383 |
| 54 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.04198762 |
| 55 | transmission of nerve impulse (GO:0019226) | 3.03390683 |
| 56 | cellular anion homeostasis (GO:0030002) | 3.00566031 |
| 57 | regulation of endothelial cell differentiation (GO:0045601) | 3.00187702 |
| 58 | regulation of germinal center formation (GO:0002634) | 2.99195535 |
| 59 | pharyngeal system development (GO:0060037) | 2.97997652 |
| 60 | positive regulation of cardiac muscle cell differentiation (GO:2000727) | 2.89916073 |
| 61 | indole-containing compound metabolic process (GO:0042430) | 2.86351192 |
| 62 | dendritic spine morphogenesis (GO:0060997) | 2.81756536 |
| 63 | endoderm formation (GO:0001706) | 2.79906540 |
| 64 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.79511332 |
| 65 | interferon-gamma secretion (GO:0072643) | 2.79278397 |
| 66 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.74061574 |
| 67 | multicellular organismal signaling (GO:0035637) | 2.70798402 |
| 68 | regulation of transcription regulatory region DNA binding (GO:2000677) | 2.70108892 |
| 69 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.69032819 |
| 70 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.69032819 |
| 71 | negative regulation of protein localization to cell surface (GO:2000009) | 2.67970932 |
| 72 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 2.66712814 |
| 73 | activated T cell proliferation (GO:0050798) | 2.65784132 |
| 74 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.64537044 |
| 75 | potassium ion import (GO:0010107) | 2.59795691 |
| 76 | cellular response to ATP (GO:0071318) | 2.58104684 |
| 77 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.57684498 |
| 78 | prostate gland growth (GO:0060736) | 2.53920361 |
| 79 | neuronal action potential (GO:0019228) | 2.53403041 |
| 80 | regulation of action potential (GO:0098900) | 2.48206780 |
| 81 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.48139404 |
| 82 | positive regulation of glomerulus development (GO:0090193) | 2.47033325 |
| 83 | regulation of gene silencing by RNA (GO:0060966) | 2.45499513 |
| 84 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.45499513 |
| 85 | regulation of gene silencing by miRNA (GO:0060964) | 2.45499513 |
| 86 | regulation of female receptivity (GO:0045924) | 2.45354408 |
| 87 | action potential (GO:0001508) | 2.45345142 |
| 88 | spinal cord development (GO:0021510) | 2.45038125 |
| 89 | detection of light stimulus involved in visual perception (GO:0050908) | 2.44316458 |
| 90 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.44316458 |
| 91 | monoubiquitinated protein deubiquitination (GO:0035520) | 2.42402400 |
| 92 | protein K48-linked deubiquitination (GO:0071108) | 2.42325327 |
| 93 | behavioral defense response (GO:0002209) | 2.41580419 |
| 94 | behavioral fear response (GO:0001662) | 2.41580419 |
| 95 | adaptation of signaling pathway (GO:0023058) | 2.40989504 |
| 96 | cardiac conduction (GO:0061337) | 2.40861489 |
| 97 | tooth mineralization (GO:0034505) | 2.40335762 |
| 98 | response to electrical stimulus (GO:0051602) | 2.39766314 |
| 99 | spinal cord motor neuron differentiation (GO:0021522) | 2.39546711 |
| 100 | positive regulation of defense response to virus by host (GO:0002230) | 2.39069884 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.55801346 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.91665336 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.43604704 |
| 4 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 3.12527637 |
| 5 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.84951562 |
| 6 | VDR_22108803_ChIP-Seq_LS180_Human | 2.54171360 |
| 7 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.44830814 |
| 8 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.42782711 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.38093673 |
| 10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.30794020 |
| 11 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.29101630 |
| 12 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.27662449 |
| 13 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.25695051 |
| 14 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.19361890 |
| 15 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.17626351 |
| 16 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.11569852 |
| 17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.08772684 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.07017520 |
| 19 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.02134898 |
| 20 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.01405632 |
| 21 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.94177695 |
| 22 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.92492555 |
| 23 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89785532 |
| 24 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.86000361 |
| 25 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.85816937 |
| 26 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.84619476 |
| 27 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.84553679 |
| 28 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.84553679 |
| 29 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.80843674 |
| 30 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.78413568 |
| 31 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.73976261 |
| 32 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.73337645 |
| 33 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.71712302 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.71303944 |
| 35 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.68067290 |
| 36 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.66272334 |
| 37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.65636626 |
| 38 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.56938912 |
| 39 | P300_19829295_ChIP-Seq_ESCs_Human | 1.48628535 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.45627254 |
| 41 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.44136815 |
| 42 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.38833201 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.37346051 |
| 44 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.33874987 |
| 45 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.33711346 |
| 46 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.33494700 |
| 47 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.32056009 |
| 48 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.31582758 |
| 49 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.29005274 |
| 50 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.28614127 |
| 51 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.27045719 |
| 52 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.24462912 |
| 53 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.22700903 |
| 54 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.19470341 |
| 55 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.18276600 |
| 56 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17596835 |
| 57 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17596835 |
| 58 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.16510745 |
| 59 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.15964774 |
| 60 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.15452931 |
| 61 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.14128510 |
| 62 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.12997172 |
| 63 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12997172 |
| 64 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.12811423 |
| 65 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.12409599 |
| 66 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.12038961 |
| 67 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.11138182 |
| 68 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11025712 |
| 69 | STAT3_23295773_ChIP-Seq_U87_Human | 1.08731879 |
| 70 | AR_25329375_ChIP-Seq_VCAP_Human | 1.08476119 |
| 71 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.08385517 |
| 72 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.07693952 |
| 73 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.06809646 |
| 74 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06589338 |
| 75 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.06075202 |
| 76 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.05881012 |
| 77 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05143895 |
| 78 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.04297555 |
| 79 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.03886277 |
| 80 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.03530784 |
| 81 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.03324791 |
| 82 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.02947104 |
| 83 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.02899289 |
| 84 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.02444742 |
| 85 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02268415 |
| 86 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.01861041 |
| 87 | TCF4_23295773_ChIP-Seq_U87_Human | 1.01166088 |
| 88 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.00726294 |
| 89 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.00389623 |
| 90 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.99708442 |
| 91 | RXR_22108803_ChIP-Seq_LS180_Human | 0.96727057 |
| 92 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.93333357 |
| 93 | JUN_21703547_ChIP-Seq_K562_Human | 0.93132959 |
| 94 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.92588578 |
| 95 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91996020 |
| 96 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.91991749 |
| 97 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.90520318 |
| 98 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.89580432 |
| 99 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 0.88598234 |
| 100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.87494222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 4.03698482 |
| 2 | MP0002837_dystrophic_cardiac_calcinosis | 3.36860614 |
| 3 | MP0004885_abnormal_endolymph | 3.04716781 |
| 4 | MP0006292_abnormal_olfactory_placode | 2.95954707 |
| 5 | MP0001485_abnormal_pinna_reflex | 2.40859588 |
| 6 | MP0002160_abnormal_reproductive_system | 2.40458633 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.30102351 |
| 8 | MP0001968_abnormal_touch/_nociception | 2.27458412 |
| 9 | MP0004145_abnormal_muscle_electrophysio | 2.24854979 |
| 10 | MP0001440_abnormal_grooming_behavior | 2.17331696 |
| 11 | MP0006072_abnormal_retinal_apoptosis | 2.16029257 |
| 12 | MP0004130_abnormal_muscle_cell | 2.10412959 |
| 13 | MP0002272_abnormal_nervous_system | 2.07183112 |
| 14 | MP0000049_abnormal_middle_ear | 2.05440431 |
| 15 | MP0005389_reproductive_system_phenotype | 1.90694703 |
| 16 | MP0003011_delayed_dark_adaptation | 1.88529351 |
| 17 | MP0002736_abnormal_nociception_after | 1.87776829 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.87059314 |
| 19 | MP0004742_abnormal_vestibular_system | 1.82019598 |
| 20 | MP0009745_abnormal_behavioral_response | 1.81269916 |
| 21 | MP0008775_abnormal_heart_ventricle | 1.80410460 |
| 22 | MP0003879_abnormal_hair_cell | 1.78082981 |
| 23 | MP0004133_heterotaxia | 1.75628310 |
| 24 | MP0000631_abnormal_neuroendocrine_gland | 1.74570191 |
| 25 | MP0004142_abnormal_muscle_tone | 1.71407094 |
| 26 | MP0002735_abnormal_chemical_nociception | 1.70969271 |
| 27 | MP0000569_abnormal_digit_pigmentation | 1.70912528 |
| 28 | MP0009379_abnormal_foot_pigmentation | 1.65717262 |
| 29 | MP0005551_abnormal_eye_electrophysiolog | 1.64736189 |
| 30 | MP0001905_abnormal_dopamine_level | 1.56879640 |
| 31 | MP0001486_abnormal_startle_reflex | 1.53408213 |
| 32 | MP0002138_abnormal_hepatobiliary_system | 1.51636417 |
| 33 | MP0002733_abnormal_thermal_nociception | 1.50093371 |
| 34 | MP0002876_abnormal_thyroid_physiology | 1.46342392 |
| 35 | MP0009046_muscle_twitch | 1.45277090 |
| 36 | MP0002102_abnormal_ear_morphology | 1.44942155 |
| 37 | MP0002064_seizures | 1.43517729 |
| 38 | MP0000026_abnormal_inner_ear | 1.43150894 |
| 39 | MP0003635_abnormal_synaptic_transmissio | 1.36761686 |
| 40 | MP0001970_abnormal_pain_threshold | 1.33360601 |
| 41 | MP0003880_abnormal_central_pattern | 1.33140683 |
| 42 | MP0002572_abnormal_emotion/affect_behav | 1.32320631 |
| 43 | MP0002638_abnormal_pupillary_reflex | 1.30334703 |
| 44 | MP0002557_abnormal_social/conspecific_i | 1.29633206 |
| 45 | MP0003787_abnormal_imprinting | 1.28384274 |
| 46 | MP0008872_abnormal_physiological_respon | 1.28194535 |
| 47 | MP0002938_white_spotting | 1.26910420 |
| 48 | MP0002184_abnormal_innervation | 1.26694272 |
| 49 | MP0009250_abnormal_appendicular_skeleto | 1.26603042 |
| 50 | MP0001963_abnormal_hearing_physiology | 1.26158905 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.24915060 |
| 52 | MP0002653_abnormal_ependyma_morphology | 1.22317851 |
| 53 | MP0003890_abnormal_embryonic-extraembry | 1.22142170 |
| 54 | MP0005423_abnormal_somatic_nervous | 1.22089415 |
| 55 | MP0000230_abnormal_systemic_arterial | 1.20633262 |
| 56 | MP0005253_abnormal_eye_physiology | 1.20080532 |
| 57 | MP0002063_abnormal_learning/memory/cond | 1.18248921 |
| 58 | MP0003283_abnormal_digestive_organ | 1.18085547 |
| 59 | MP0003119_abnormal_digestive_system | 1.16005240 |
| 60 | MP0003942_abnormal_urinary_system | 1.15064444 |
| 61 | MP0003122_maternal_imprinting | 1.14442751 |
| 62 | MP0001919_abnormal_reproductive_system | 1.13610934 |
| 63 | MP0003937_abnormal_limbs/digits/tail_de | 1.11519772 |
| 64 | MP0003938_abnormal_ear_development | 1.10375125 |
| 65 | MP0002752_abnormal_somatic_nervous | 1.07368716 |
| 66 | MP0002928_abnormal_bile_duct | 1.06134059 |
| 67 | MP0002734_abnormal_mechanical_nocicepti | 1.05957905 |
| 68 | MP0004215_abnormal_myocardial_fiber | 1.04623824 |
| 69 | MP0004134_abnormal_chest_morphology | 1.04510443 |
| 70 | MP0004085_abnormal_heartbeat | 1.04278252 |
| 71 | MP0002067_abnormal_sensory_capabilities | 1.04062143 |
| 72 | MP0000778_abnormal_nervous_system | 1.03352241 |
| 73 | MP0002163_abnormal_gland_morphology | 1.01779526 |
| 74 | MP0008789_abnormal_olfactory_epithelium | 1.01346491 |
| 75 | MP0001502_abnormal_circadian_rhythm | 1.00155547 |
| 76 | MP0009053_abnormal_anal_canal | 0.98870077 |
| 77 | MP0005386_behavior/neurological_phenoty | 0.98669613 |
| 78 | MP0004924_abnormal_behavior | 0.98669613 |
| 79 | MP0005084_abnormal_gallbladder_morpholo | 0.97134243 |
| 80 | MP0005195_abnormal_posterior_eye | 0.94834171 |
| 81 | MP0003567_abnormal_fetal_cardiomyocyte | 0.94446366 |
| 82 | MP0003123_paternal_imprinting | 0.94422214 |
| 83 | MP0003121_genomic_imprinting | 0.93650805 |
| 84 | MP0002277_abnormal_respiratory_mucosa | 0.89933174 |
| 85 | MP0003195_calcinosis | 0.87291276 |
| 86 | MP0001986_abnormal_taste_sensitivity | 0.86498434 |
| 87 | MP0004019_abnormal_vitamin_homeostasis | 0.86377023 |
| 88 | MP0004859_abnormal_synaptic_plasticity | 0.85626924 |
| 89 | MP0000955_abnormal_spinal_cord | 0.84016610 |
| 90 | MP0002882_abnormal_neuron_morphology | 0.82049470 |
| 91 | MP0001188_hyperpigmentation | 0.81708280 |
| 92 | MP0002932_abnormal_joint_morphology | 0.80711348 |
| 93 | MP0001529_abnormal_vocalization | 0.76773757 |
| 94 | MP0003137_abnormal_impulse_conducting | 0.76238531 |
| 95 | MP0001765_abnormal_ion_homeostasis | 0.76063792 |
| 96 | MP0002229_neurodegeneration | 0.73399348 |
| 97 | MP0000534_abnormal_ureter_morphology | 0.72759616 |
| 98 | MP0009384_cardiac_valve_regurgitation | 0.70331183 |
| 99 | MP0003638_abnormal_response/metabolism_ | 0.70256800 |
| 100 | MP0003633_abnormal_nervous_system | 0.66589363 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.63803853 |
| 2 | Short femoral neck (HP:0100864) | 3.51805393 |
| 3 | Abolished electroretinogram (ERG) (HP:0000550) | 3.36988624 |
| 4 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.36011616 |
| 5 | Abnormality of the middle phalanges of the toes (HP:0010183) | 3.26237836 |
| 6 | Short 4th metacarpal (HP:0010044) | 3.25608206 |
| 7 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.25608206 |
| 8 | Pancreatic cysts (HP:0001737) | 3.22856402 |
| 9 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 3.18468594 |
| 10 | Short tibia (HP:0005736) | 3.18321019 |
| 11 | Congenital, generalized hypertrichosis (HP:0004540) | 3.16511797 |
| 12 | Decreased circulating renin level (HP:0003351) | 3.16113952 |
| 13 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 3.13824410 |
| 14 | Pancreatic fibrosis (HP:0100732) | 3.13259112 |
| 15 | Mesomelia (HP:0003027) | 3.11468862 |
| 16 | Conjunctival hamartoma (HP:0100780) | 3.10147731 |
| 17 | Nephronophthisis (HP:0000090) | 3.04832637 |
| 18 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 3.00148315 |
| 19 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.97332867 |
| 20 | Hypoplasia of the uterus (HP:0000013) | 2.97049877 |
| 21 | True hermaphroditism (HP:0010459) | 2.96824623 |
| 22 | Progressive cerebellar ataxia (HP:0002073) | 2.92788912 |
| 23 | Congenital stationary night blindness (HP:0007642) | 2.89807386 |
| 24 | Fibular aplasia (HP:0002990) | 2.85683137 |
| 25 | Meningioma (HP:0002858) | 2.85332681 |
| 26 | Pendular nystagmus (HP:0012043) | 2.84777910 |
| 27 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.82811540 |
| 28 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.82338006 |
| 29 | Hypoplasia of the ulna (HP:0003022) | 2.79306002 |
| 30 | Aplasia/Hypoplasia of the fibula (HP:0006492) | 2.76975232 |
| 31 | Megalencephaly (HP:0001355) | 2.76699532 |
| 32 | Genetic anticipation (HP:0003743) | 2.74177518 |
| 33 | Cutaneous melanoma (HP:0012056) | 2.69954238 |
| 34 | Short hallux (HP:0010109) | 2.69061988 |
| 35 | Methylmalonic acidemia (HP:0002912) | 2.66529526 |
| 36 | Abnormality of the 4th metacarpal (HP:0010012) | 2.64640419 |
| 37 | Molar tooth sign on MRI (HP:0002419) | 2.63614662 |
| 38 | Abnormality of midbrain morphology (HP:0002418) | 2.63614662 |
| 39 | Clumsiness (HP:0002312) | 2.63397114 |
| 40 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.59850193 |
| 41 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.59506222 |
| 42 | Abnormality of the renal collecting system (HP:0004742) | 2.58054012 |
| 43 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.50869469 |
| 44 | Abnormality of the renal medulla (HP:0100957) | 2.49134428 |
| 45 | Adactyly (HP:0009776) | 2.48823054 |
| 46 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.45964470 |
| 47 | Furrowed tongue (HP:0000221) | 2.44129623 |
| 48 | Fibular hypoplasia (HP:0003038) | 2.42974886 |
| 49 | Aplasia/hypoplasia of the femur (HP:0005613) | 2.33908989 |
| 50 | Radial bowing (HP:0002986) | 2.33900148 |
| 51 | Goiter (HP:0000853) | 2.30810264 |
| 52 | Metabolic alkalosis (HP:0200114) | 2.28522400 |
| 53 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.27402789 |
| 54 | Methylmalonic aciduria (HP:0012120) | 2.26863479 |
| 55 | Agitation (HP:0000713) | 2.26661240 |
| 56 | Asplenia (HP:0001746) | 2.25379880 |
| 57 | Aplasia/Hypoplasia of the ulna (HP:0006495) | 2.24881575 |
| 58 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 2.24342612 |
| 59 | Decreased central vision (HP:0007663) | 2.24213690 |
| 60 | Congenital sensorineural hearing impairment (HP:0008527) | 2.22397664 |
| 61 | Hamartoma of the eye (HP:0010568) | 2.18096900 |
| 62 | Stenosis of the external auditory canal (HP:0000402) | 2.17738011 |
| 63 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.16554916 |
| 64 | Morphological abnormality of the middle ear (HP:0008609) | 2.15260058 |
| 65 | 3-Methylglutaconic aciduria (HP:0003535) | 2.12395264 |
| 66 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.10088345 |
| 67 | Small hand (HP:0200055) | 2.07927771 |
| 68 | Synostosis of carpal bones (HP:0005048) | 2.07724180 |
| 69 | Hyperglycinemia (HP:0002154) | 2.07145632 |
| 70 | Abnormality of the renal cortex (HP:0011035) | 2.06190375 |
| 71 | Mitochondrial inheritance (HP:0001427) | 2.04399133 |
| 72 | Bone cyst (HP:0012062) | 2.03169273 |
| 73 | Keratoconus (HP:0000563) | 2.02300445 |
| 74 | Increased corneal curvature (HP:0100692) | 2.02300445 |
| 75 | Acute necrotizing encephalopathy (HP:0006965) | 2.02266116 |
| 76 | Chorioretinal atrophy (HP:0000533) | 2.02216662 |
| 77 | Abnormality of the nasal septum (HP:0000419) | 2.00957874 |
| 78 | Septo-optic dysplasia (HP:0100842) | 1.99509510 |
| 79 | Cystic liver disease (HP:0006706) | 1.99327644 |
| 80 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.98215883 |
| 81 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.97439955 |
| 82 | Abnormality of alanine metabolism (HP:0010916) | 1.97439955 |
| 83 | Hyperalaninemia (HP:0003348) | 1.97439955 |
| 84 | Sclerocornea (HP:0000647) | 1.97151296 |
| 85 | Abnormal number of erythroid precursors (HP:0012131) | 1.97122816 |
| 86 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.94461683 |
| 87 | Osteomalacia (HP:0002749) | 1.93332825 |
| 88 | Medial flaring of the eyebrow (HP:0010747) | 1.92881013 |
| 89 | Broad-based gait (HP:0002136) | 1.88357114 |
| 90 | Abnormality of the 2nd finger (HP:0004100) | 1.87393011 |
| 91 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.86944029 |
| 92 | Anomalous pulmonary venous return (HP:0010772) | 1.86764123 |
| 93 | Progressive macrocephaly (HP:0004481) | 1.86516266 |
| 94 | Short 1st metacarpal (HP:0010034) | 1.83375017 |
| 95 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.83375017 |
| 96 | Absent thumb (HP:0009777) | 1.82185774 |
| 97 | Persistence of primary teeth (HP:0006335) | 1.81389882 |
| 98 | Forearm undergrowth (HP:0009821) | 1.80756789 |
| 99 | Male pseudohermaphroditism (HP:0000037) | 1.80298138 |
| 100 | Preauricular pit (HP:0004467) | 1.80177486 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 5.09253440 |
| 2 | TLK1 | 3.19208802 |
| 3 | GRK1 | 3.11412431 |
| 4 | ADRBK2 | 2.94468708 |
| 5 | TAOK3 | 2.41802835 |
| 6 | BMPR1B | 2.34941013 |
| 7 | CASK | 2.17966528 |
| 8 | WNK4 | 2.07686409 |
| 9 | PINK1 | 2.02606681 |
| 10 | ZAK | 2.00462455 |
| 11 | NUAK1 | 1.78394527 |
| 12 | SGK2 | 1.73099526 |
| 13 | TAF1 | 1.71389564 |
| 14 | WNK3 | 1.58438843 |
| 15 | SGK494 | 1.57597211 |
| 16 | SGK223 | 1.57597211 |
| 17 | TNIK | 1.53680890 |
| 18 | DYRK2 | 1.53443664 |
| 19 | MAPK13 | 1.48677851 |
| 20 | GRK7 | 1.48460457 |
| 21 | MAP4K2 | 1.46608082 |
| 22 | STK16 | 1.45527513 |
| 23 | MAP3K4 | 1.45371004 |
| 24 | TIE1 | 1.44523186 |
| 25 | ACVR1B | 1.38597330 |
| 26 | BCKDK | 1.36426756 |
| 27 | TXK | 1.31043904 |
| 28 | INSRR | 1.29030397 |
| 29 | NTRK3 | 1.28605372 |
| 30 | PHKG1 | 1.20427137 |
| 31 | PHKG2 | 1.20427137 |
| 32 | NTRK2 | 1.19146262 |
| 33 | EPHB2 | 1.17910071 |
| 34 | MAP2K7 | 1.17320302 |
| 35 | RPS6KA2 | 1.17209292 |
| 36 | ADRBK1 | 1.14138008 |
| 37 | RPS6KA6 | 1.10460360 |
| 38 | GRK5 | 1.07615089 |
| 39 | FGFR2 | 1.06583424 |
| 40 | MARK1 | 1.05009504 |
| 41 | PRKCG | 1.01721193 |
| 42 | CSNK1G2 | 0.95828655 |
| 43 | DAPK2 | 0.95518904 |
| 44 | STK39 | 0.94883148 |
| 45 | PIK3CA | 0.94667946 |
| 46 | IKBKB | 0.94625559 |
| 47 | SGK3 | 0.91342559 |
| 48 | VRK2 | 0.87893743 |
| 49 | PLK2 | 0.87333252 |
| 50 | ERBB2 | 0.83980138 |
| 51 | RPS6KL1 | 0.82663922 |
| 52 | RPS6KC1 | 0.82663922 |
| 53 | PRKACA | 0.82162793 |
| 54 | CSNK1G3 | 0.82120920 |
| 55 | DYRK3 | 0.81511014 |
| 56 | VRK1 | 0.81049853 |
| 57 | WNK1 | 0.81044828 |
| 58 | PAK3 | 0.79976183 |
| 59 | MAPKAPK5 | 0.78332063 |
| 60 | NEK9 | 0.77609598 |
| 61 | OXSR1 | 0.77167781 |
| 62 | MAPK15 | 0.76648202 |
| 63 | MUSK | 0.76301110 |
| 64 | PRKCE | 0.74876025 |
| 65 | CSNK1G1 | 0.74040291 |
| 66 | STK11 | 0.73624652 |
| 67 | SGK1 | 0.73270064 |
| 68 | CSNK1A1L | 0.68543925 |
| 69 | MAP3K9 | 0.67799086 |
| 70 | OBSCN | 0.67759200 |
| 71 | CSNK1A1 | 0.67157506 |
| 72 | TEC | 0.65268849 |
| 73 | PTK2B | 0.64560799 |
| 74 | PRKD2 | 0.62451158 |
| 75 | CAMKK2 | 0.61532039 |
| 76 | RPS6KA5 | 0.60841535 |
| 77 | CAMK2A | 0.59840634 |
| 78 | AURKA | 0.58468965 |
| 79 | PNCK | 0.54724024 |
| 80 | PRKACG | 0.52021675 |
| 81 | ABL2 | 0.51640107 |
| 82 | SIK2 | 0.51145585 |
| 83 | ITK | 0.50831793 |
| 84 | PKN1 | 0.50755911 |
| 85 | HIPK2 | 0.50107484 |
| 86 | CAMK1 | 0.49984447 |
| 87 | PRKCQ | 0.48054576 |
| 88 | CHUK | 0.45868704 |
| 89 | PRKCA | 0.45845059 |
| 90 | MAPK4 | 0.45637480 |
| 91 | PRKCZ | 0.44588705 |
| 92 | MAP3K11 | 0.43795955 |
| 93 | NME1 | 0.43415225 |
| 94 | CDK19 | 0.39903374 |
| 95 | CAMK2B | 0.39705750 |
| 96 | MAP2K4 | 0.38850011 |
| 97 | MAPKAPK3 | 0.38650887 |
| 98 | MAP2K2 | 0.38098454 |
| 99 | TGFBR1 | 0.37297953 |
| 100 | KIT | 0.37062315 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.96264150 |
| 2 | Nicotine addiction_Homo sapiens_hsa05033 | 2.70570865 |
| 3 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.45319598 |
| 4 | Phototransduction_Homo sapiens_hsa04744 | 2.37059295 |
| 5 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.31836759 |
| 6 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.29088536 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.28372206 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.21518431 |
| 9 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 2.13045496 |
| 10 | Ribosome_Homo sapiens_hsa03010 | 2.09520744 |
| 11 | Morphine addiction_Homo sapiens_hsa05032 | 1.97173073 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.87171573 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.83488941 |
| 14 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.76766658 |
| 15 | Protein export_Homo sapiens_hsa03060 | 1.76235444 |
| 16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.68185156 |
| 17 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.64216423 |
| 18 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.62928906 |
| 19 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.61556782 |
| 20 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.60964871 |
| 21 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.60769963 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.60703916 |
| 23 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.59389492 |
| 24 | Huntingtons disease_Homo sapiens_hsa05016 | 1.56501491 |
| 25 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.55346430 |
| 26 | Circadian entrainment_Homo sapiens_hsa04713 | 1.52792046 |
| 27 | Retinol metabolism_Homo sapiens_hsa00830 | 1.50507305 |
| 28 | GABAergic synapse_Homo sapiens_hsa04727 | 1.50048069 |
| 29 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.47703731 |
| 30 | Insulin secretion_Homo sapiens_hsa04911 | 1.45844338 |
| 31 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.40163556 |
| 32 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.34723892 |
| 33 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.33625279 |
| 34 | Taste transduction_Homo sapiens_hsa04742 | 1.33319192 |
| 35 | Olfactory transduction_Homo sapiens_hsa04740 | 1.21473968 |
| 36 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.21396610 |
| 37 | RNA polymerase_Homo sapiens_hsa03020 | 1.17790987 |
| 38 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.16109975 |
| 39 | Basal transcription factors_Homo sapiens_hsa03022 | 1.16089240 |
| 40 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.14665883 |
| 41 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.10623102 |
| 42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.09704709 |
| 43 | Renin secretion_Homo sapiens_hsa04924 | 1.06495945 |
| 44 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.02826139 |
| 45 | Sulfur relay system_Homo sapiens_hsa04122 | 1.01730041 |
| 46 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.01609014 |
| 47 | RNA degradation_Homo sapiens_hsa03018 | 1.00513539 |
| 48 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.98545652 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.98462639 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.98081605 |
| 51 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.94926180 |
| 52 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.94885691 |
| 53 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.93510050 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.93250658 |
| 55 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.91302596 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.86769777 |
| 57 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.86535951 |
| 58 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.85076066 |
| 59 | Homologous recombination_Homo sapiens_hsa03440 | 0.82623345 |
| 60 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.80223939 |
| 61 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.79350625 |
| 62 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.77338202 |
| 63 | Cocaine addiction_Homo sapiens_hsa05030 | 0.77239775 |
| 64 | Asthma_Homo sapiens_hsa05310 | 0.75071300 |
| 65 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.73878498 |
| 66 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.72536291 |
| 67 | Melanoma_Homo sapiens_hsa05218 | 0.72129405 |
| 68 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.71332438 |
| 69 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.69322822 |
| 70 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68875747 |
| 71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65203559 |
| 72 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.63032756 |
| 73 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.63031900 |
| 74 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.62911568 |
| 75 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.62649378 |
| 76 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.62157975 |
| 77 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.61235290 |
| 78 | Salivary secretion_Homo sapiens_hsa04970 | 0.61190885 |
| 79 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.60055202 |
| 80 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.59476388 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.59098801 |
| 82 | Axon guidance_Homo sapiens_hsa04360 | 0.59010087 |
| 83 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.58120773 |
| 84 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.52330171 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.52034241 |
| 86 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.50066210 |
| 87 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47708712 |
| 88 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.46687903 |
| 89 | Long-term depression_Homo sapiens_hsa04730 | 0.44248551 |
| 90 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.42791500 |
| 91 | Alcoholism_Homo sapiens_hsa05034 | 0.42583167 |
| 92 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.41675806 |
| 93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.41359777 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40862860 |
| 95 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.39892081 |
| 96 | ABC transporters_Homo sapiens_hsa02010 | 0.39544083 |
| 97 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.37168691 |
| 98 | Metabolic pathways_Homo sapiens_hsa01100 | 0.35123325 |
| 99 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.33242798 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.32386694 |

