

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.44559751 |
| 2 | DNA deamination (GO:0045006) | 6.55100413 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.22244942 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.81676498 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 5.81676498 |
| 6 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.32771946 |
| 7 | cytidine metabolic process (GO:0046087) | 5.27460161 |
| 8 | cytidine catabolic process (GO:0006216) | 5.27460161 |
| 9 | cytidine deamination (GO:0009972) | 5.27460161 |
| 10 | viral transcription (GO:0019083) | 4.99876441 |
| 11 | translational termination (GO:0006415) | 4.82778167 |
| 12 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.78143160 |
| 13 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.58013698 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.57076216 |
| 15 | translational elongation (GO:0006414) | 4.37812923 |
| 16 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.36710212 |
| 17 | respiratory electron transport chain (GO:0022904) | 4.33045789 |
| 18 | electron transport chain (GO:0022900) | 4.30107246 |
| 19 | cotranslational protein targeting to membrane (GO:0006613) | 4.28365153 |
| 20 | protein targeting to ER (GO:0045047) | 4.27502294 |
| 21 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.06746945 |
| 22 | protein localization to endoplasmic reticulum (GO:0070972) | 4.06527274 |
| 23 | chaperone-mediated protein transport (GO:0072321) | 3.87936898 |
| 24 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.83348212 |
| 25 | ribosomal small subunit biogenesis (GO:0042274) | 3.82088164 |
| 26 | protein complex biogenesis (GO:0070271) | 3.81762124 |
| 27 | protein neddylation (GO:0045116) | 3.80579733 |
| 28 | translational initiation (GO:0006413) | 3.66934127 |
| 29 | pseudouridine synthesis (GO:0001522) | 3.66725276 |
| 30 | proteasome assembly (GO:0043248) | 3.63820500 |
| 31 | viral life cycle (GO:0019058) | 3.61270143 |
| 32 | cellular protein complex disassembly (GO:0043624) | 3.60679820 |
| 33 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.58074893 |
| 34 | NADH dehydrogenase complex assembly (GO:0010257) | 3.58074893 |
| 35 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.58074893 |
| 36 | translation (GO:0006412) | 3.53866774 |
| 37 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.52666652 |
| 38 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.51884150 |
| 39 | ribosomal large subunit biogenesis (GO:0042273) | 3.51677767 |
| 40 | rRNA modification (GO:0000154) | 3.51430032 |
| 41 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.50408786 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.46951791 |
| 43 | maturation of SSU-rRNA (GO:0030490) | 3.46255849 |
| 44 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.37302145 |
| 45 | ATP biosynthetic process (GO:0006754) | 3.36164250 |
| 46 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.36040685 |
| 47 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.30312920 |
| 48 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.30138253 |
| 49 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.26284899 |
| 50 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.26284899 |
| 51 | respiratory chain complex IV assembly (GO:0008535) | 3.23680771 |
| 52 | hydrogen ion transmembrane transport (GO:1902600) | 3.17332129 |
| 53 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.17235290 |
| 54 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.14558770 |
| 55 | platelet dense granule organization (GO:0060155) | 3.13316918 |
| 56 | behavioral response to nicotine (GO:0035095) | 3.06907343 |
| 57 | termination of RNA polymerase III transcription (GO:0006386) | 3.03325095 |
| 58 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.03325095 |
| 59 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.03111463 |
| 60 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.01893779 |
| 61 | actin nucleation (GO:0045010) | 3.01730270 |
| 62 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.00885076 |
| 63 | negative regulation of ligase activity (GO:0051352) | 3.00885076 |
| 64 | cytochrome complex assembly (GO:0017004) | 2.96813069 |
| 65 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.94925416 |
| 66 | iron-sulfur cluster assembly (GO:0016226) | 2.92373715 |
| 67 | metallo-sulfur cluster assembly (GO:0031163) | 2.92373715 |
| 68 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.91561624 |
| 69 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.91561624 |
| 70 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.91561624 |
| 71 | cellular component biogenesis (GO:0044085) | 2.91043357 |
| 72 | protein complex disassembly (GO:0043241) | 2.90460614 |
| 73 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.89699157 |
| 74 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.89699157 |
| 75 | mannosylation (GO:0097502) | 2.89278075 |
| 76 | response to interferon-beta (GO:0035456) | 2.87013148 |
| 77 | proton transport (GO:0015992) | 2.86975043 |
| 78 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.84442326 |
| 79 | hydrogen transport (GO:0006818) | 2.82595743 |
| 80 | base-excision repair, AP site formation (GO:0006285) | 2.80462702 |
| 81 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.79938506 |
| 82 | deoxyribonucleotide catabolic process (GO:0009264) | 2.79782123 |
| 83 | deoxyribose phosphate catabolic process (GO:0046386) | 2.79296251 |
| 84 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.79209096 |
| 85 | rRNA processing (GO:0006364) | 2.77991479 |
| 86 | macromolecular complex disassembly (GO:0032984) | 2.77164350 |
| 87 | rRNA methylation (GO:0031167) | 2.75228712 |
| 88 | rRNA metabolic process (GO:0016072) | 2.74018837 |
| 89 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.73897897 |
| 90 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.73897897 |
| 91 | protein targeting to membrane (GO:0006612) | 2.72813388 |
| 92 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.71193755 |
| 93 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.69037475 |
| 94 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.68509052 |
| 95 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.66340261 |
| 96 | GPI anchor biosynthetic process (GO:0006506) | 2.63503532 |
| 97 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.62674761 |
| 98 | mRNA catabolic process (GO:0006402) | 2.62130676 |
| 99 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.61453982 |
| 100 | sequestering of actin monomers (GO:0042989) | 2.60353451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.24318322 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.14702588 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.96375326 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.55734722 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.52236964 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.37739510 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.33388644 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.94748577 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.84549179 |
| 10 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.82510031 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.73190174 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.71844400 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.66168230 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.51897888 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.50079312 |
| 16 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.28798618 |
| 17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.18661498 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.13841653 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.10994622 |
| 20 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.07077427 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.06328417 |
| 22 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.05980193 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.96326905 |
| 24 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.94679351 |
| 25 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.91880951 |
| 26 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.88333186 |
| 27 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.86141769 |
| 28 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.82991402 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.74336187 |
| 30 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.73017107 |
| 31 | EWS_26573619_Chip-Seq_HEK293_Human | 1.69687484 |
| 32 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.59038851 |
| 33 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.53521378 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.48572344 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.46611555 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.46199520 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.45638611 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.43084450 |
| 39 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.40711969 |
| 40 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.40711969 |
| 41 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40138303 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.39474295 |
| 43 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.34742298 |
| 44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.34232221 |
| 45 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.32083799 |
| 46 | MYB_26560356_Chip-Seq_TH2_Human | 1.31614752 |
| 47 | AR_20517297_ChIP-Seq_VCAP_Human | 1.30898114 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.30644157 |
| 49 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.29611166 |
| 50 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.29176033 |
| 51 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.28350477 |
| 52 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.27496809 |
| 53 | GATA3_26560356_Chip-Seq_TH2_Human | 1.27219330 |
| 54 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.23195443 |
| 55 | NCOR_22424771_ChIP-Seq_293T_Human | 1.21651699 |
| 56 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.21255221 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.19513114 |
| 58 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.18979899 |
| 59 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.18979899 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.18142285 |
| 61 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.16931376 |
| 62 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.16560742 |
| 63 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.15232213 |
| 64 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14844846 |
| 65 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.14175855 |
| 66 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.11526413 |
| 67 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.10257983 |
| 68 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.08017082 |
| 69 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.07496632 |
| 70 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.04916462 |
| 71 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03944194 |
| 72 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.03784390 |
| 73 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.03342147 |
| 74 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.02821657 |
| 75 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.02283778 |
| 76 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02267769 |
| 77 | P300_19829295_ChIP-Seq_ESCs_Human | 1.02057394 |
| 78 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01202492 |
| 79 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.01135550 |
| 80 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.00294228 |
| 81 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.99800023 |
| 82 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.99609448 |
| 83 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99131382 |
| 84 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.99091056 |
| 85 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.99066122 |
| 86 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.97426922 |
| 87 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.96059201 |
| 88 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.95414997 |
| 89 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.94966402 |
| 90 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94136370 |
| 91 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.94126201 |
| 92 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.94126201 |
| 93 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.93861876 |
| 94 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.92443454 |
| 95 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.92057085 |
| 96 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91524064 |
| 97 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.90675500 |
| 98 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.90212008 |
| 99 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.88835045 |
| 100 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.88097151 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.16945041 |
| 2 | MP0005671_abnormal_response_to | 3.65436945 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.05035384 |
| 4 | MP0006292_abnormal_olfactory_placode | 2.91100934 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 2.59097817 |
| 6 | MP0002102_abnormal_ear_morphology | 2.54274809 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 2.36575275 |
| 8 | MP0009785_altered_susceptibility_to | 2.33658090 |
| 9 | MP0001873_stomach_inflammation | 2.25194163 |
| 10 | MP0005084_abnormal_gallbladder_morpholo | 2.24888517 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.19528923 |
| 12 | MP0006072_abnormal_retinal_apoptosis | 2.12024036 |
| 13 | MP0002837_dystrophic_cardiac_calcinosis | 1.87406728 |
| 14 | MP0004147_increased_porphyrin_level | 1.86259076 |
| 15 | MP0008877_abnormal_DNA_methylation | 1.82487238 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 1.81457503 |
| 17 | MP0002166_altered_tumor_susceptibility | 1.79361772 |
| 18 | MP0003763_abnormal_thymus_physiology | 1.74225800 |
| 19 | MP0001800_abnormal_humoral_immune | 1.72173463 |
| 20 | MP0000685_abnormal_immune_system | 1.65782965 |
| 21 | MP0008872_abnormal_physiological_respon | 1.60271372 |
| 22 | MP0003786_premature_aging | 1.59541110 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.57511846 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.57057774 |
| 25 | MP0005645_abnormal_hypothalamus_physiol | 1.51741378 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.51321451 |
| 27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.50807865 |
| 28 | MP0002006_tumorigenesis | 1.49601919 |
| 29 | MP0001905_abnormal_dopamine_level | 1.48477312 |
| 30 | MP0005387_immune_system_phenotype | 1.46549207 |
| 31 | MP0001790_abnormal_immune_system | 1.46549207 |
| 32 | MP0003646_muscle_fatigue | 1.44839799 |
| 33 | MP0005000_abnormal_immune_tolerance | 1.43462592 |
| 34 | MP0008995_early_reproductive_senescence | 1.42318040 |
| 35 | MP0004142_abnormal_muscle_tone | 1.40784892 |
| 36 | MP0001764_abnormal_homeostasis | 1.39867826 |
| 37 | MP0002163_abnormal_gland_morphology | 1.39573194 |
| 38 | MP0002638_abnormal_pupillary_reflex | 1.39459232 |
| 39 | MP0003787_abnormal_imprinting | 1.38452138 |
| 40 | MP0002723_abnormal_immune_serum | 1.37900008 |
| 41 | MP0005379_endocrine/exocrine_gland_phen | 1.37083503 |
| 42 | MP0003567_abnormal_fetal_cardiomyocyte | 1.36858744 |
| 43 | MP0002420_abnormal_adaptive_immunity | 1.33431498 |
| 44 | MP0001819_abnormal_immune_cell | 1.30229857 |
| 45 | MP0005253_abnormal_eye_physiology | 1.27012754 |
| 46 | MP0001188_hyperpigmentation | 1.26689395 |
| 47 | MP0001986_abnormal_taste_sensitivity | 1.26427888 |
| 48 | MP0005389_reproductive_system_phenotype | 1.24725740 |
| 49 | MP0002277_abnormal_respiratory_mucosa | 1.23992391 |
| 50 | MP0008058_abnormal_DNA_repair | 1.23428529 |
| 51 | MP0002132_abnormal_respiratory_system | 1.22683666 |
| 52 | MP0003186_abnormal_redox_activity | 1.21502161 |
| 53 | MP0005025_abnormal_response_to | 1.18214255 |
| 54 | MP0002452_abnormal_antigen_presenting | 1.17480547 |
| 55 | MP0002398_abnormal_bone_marrow | 1.17188585 |
| 56 | MP0003195_calcinosis | 1.15969893 |
| 57 | MP0000716_abnormal_immune_system | 1.14605397 |
| 58 | MP0001293_anophthalmia | 1.14121529 |
| 59 | MP0004145_abnormal_muscle_electrophysio | 1.10925419 |
| 60 | MP0001968_abnormal_touch/_nociception | 1.09766387 |
| 61 | MP0002095_abnormal_skin_pigmentation | 1.07349946 |
| 62 | MP0003878_abnormal_ear_physiology | 1.07066849 |
| 63 | MP0005377_hearing/vestibular/ear_phenot | 1.07066849 |
| 64 | MP0000689_abnormal_spleen_morphology | 1.06171838 |
| 65 | MP0006036_abnormal_mitochondrial_physio | 1.05429000 |
| 66 | MP0002160_abnormal_reproductive_system | 1.03397051 |
| 67 | MP0003806_abnormal_nucleotide_metabolis | 1.02737397 |
| 68 | MP0006276_abnormal_autonomic_nervous | 1.02691256 |
| 69 | MP0004885_abnormal_endolymph | 1.01880276 |
| 70 | MP0001919_abnormal_reproductive_system | 1.01514184 |
| 71 | MP0005410_abnormal_fertilization | 1.01338566 |
| 72 | MP0002876_abnormal_thyroid_physiology | 1.00159039 |
| 73 | MP0002736_abnormal_nociception_after | 0.99106011 |
| 74 | MP0003866_abnormal_defecation | 0.96173850 |
| 75 | MP0006082_CNS_inflammation | 0.95228449 |
| 76 | MP0001485_abnormal_pinna_reflex | 0.94965248 |
| 77 | MP0000703_abnormal_thymus_morphology | 0.93838578 |
| 78 | MP0002653_abnormal_ependyma_morphology | 0.93561435 |
| 79 | MP0002722_abnormal_immune_system | 0.93150609 |
| 80 | MP0002693_abnormal_pancreas_physiology | 0.93043901 |
| 81 | MP0010155_abnormal_intestine_physiology | 0.92719318 |
| 82 | MP0003718_maternal_effect | 0.91866109 |
| 83 | MP0002429_abnormal_blood_cell | 0.90476913 |
| 84 | MP0005636_abnormal_mineral_homeostasis | 0.89459040 |
| 85 | MP0002405_respiratory_system_inflammati | 0.88293625 |
| 86 | MP0001845_abnormal_inflammatory_respons | 0.83977547 |
| 87 | MP0009764_decreased_sensitivity_to | 0.81849374 |
| 88 | MP0002234_abnormal_pharynx_morphology | 0.80742896 |
| 89 | MP0004742_abnormal_vestibular_system | 0.74727788 |
| 90 | MP0000678_abnormal_parathyroid_gland | 0.74696871 |
| 91 | MP0003011_delayed_dark_adaptation | 0.74322722 |
| 92 | MP0008007_abnormal_cellular_replicative | 0.74011644 |
| 93 | MP0008469_abnormal_protein_level | 0.73563132 |
| 94 | MP0000631_abnormal_neuroendocrine_gland | 0.71528263 |
| 95 | MP0001661_extended_life_span | 0.69894797 |
| 96 | MP0002272_abnormal_nervous_system | 0.68785483 |
| 97 | MP0005464_abnormal_platelet_physiology | 0.68692247 |
| 98 | MP0001529_abnormal_vocalization | 0.68673170 |
| 99 | MP0002938_white_spotting | 0.68079660 |
| 100 | MP0002019_abnormal_tumor_incidence | 0.66512776 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.67476941 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.66441952 |
| 3 | Increased hepatocellular lipid droplets (HP:0006565) | 4.61061556 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 4.16650310 |
| 5 | Increased CSF lactate (HP:0002490) | 4.14869726 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.05711127 |
| 7 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.05080855 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.95841654 |
| 9 | Aplastic anemia (HP:0001915) | 3.89776135 |
| 10 | Acute encephalopathy (HP:0006846) | 3.86668532 |
| 11 | Renal Fanconi syndrome (HP:0001994) | 3.84967684 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.74292828 |
| 13 | Hepatic necrosis (HP:0002605) | 3.44930783 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.43938994 |
| 15 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.40744314 |
| 16 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.35800088 |
| 17 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.33810470 |
| 18 | Cerebral edema (HP:0002181) | 3.32568097 |
| 19 | Congenital stationary night blindness (HP:0007642) | 3.32304083 |
| 20 | Exertional dyspnea (HP:0002875) | 3.28063347 |
| 21 | Pancreatic cysts (HP:0001737) | 3.11702414 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 3.09920117 |
| 23 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.97236238 |
| 24 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.94170428 |
| 25 | Pancreatic fibrosis (HP:0100732) | 2.88373091 |
| 26 | Increased serum lactate (HP:0002151) | 2.88142598 |
| 27 | Abolished electroretinogram (ERG) (HP:0000550) | 2.85275755 |
| 28 | Increased muscle lipid content (HP:0009058) | 2.84572162 |
| 29 | IgG deficiency (HP:0004315) | 2.78781398 |
| 30 | True hermaphroditism (HP:0010459) | 2.77438114 |
| 31 | Optic disc pallor (HP:0000543) | 2.74280689 |
| 32 | Reticulocytopenia (HP:0001896) | 2.62415705 |
| 33 | Lactic acidosis (HP:0003128) | 2.59973456 |
| 34 | Decreased central vision (HP:0007663) | 2.58867124 |
| 35 | Reduced antithrombin III activity (HP:0001976) | 2.56266179 |
| 36 | T lymphocytopenia (HP:0005403) | 2.53459414 |
| 37 | Abnormality of midbrain morphology (HP:0002418) | 2.52230506 |
| 38 | Molar tooth sign on MRI (HP:0002419) | 2.52230506 |
| 39 | Abnormal number of erythroid precursors (HP:0012131) | 2.52113789 |
| 40 | Macrocytic anemia (HP:0001972) | 2.51234825 |
| 41 | Methylmalonic acidemia (HP:0002912) | 2.51036099 |
| 42 | Abnormality of urine glucose concentration (HP:0011016) | 2.48325836 |
| 43 | Glycosuria (HP:0003076) | 2.48325836 |
| 44 | Hypoproteinemia (HP:0003075) | 2.44988678 |
| 45 | Respiratory difficulties (HP:0002880) | 2.43408280 |
| 46 | Attenuation of retinal blood vessels (HP:0007843) | 2.42740626 |
| 47 | Abnormality of renal resorption (HP:0011038) | 2.41641306 |
| 48 | Abnormality of B cell number (HP:0010975) | 2.40905255 |
| 49 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.39737910 |
| 50 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.39737910 |
| 51 | B lymphocytopenia (HP:0010976) | 2.39022837 |
| 52 | Severe combined immunodeficiency (HP:0004430) | 2.35325461 |
| 53 | Abnormality of T cell number (HP:0011839) | 2.33538921 |
| 54 | Congenital, generalized hypertrichosis (HP:0004540) | 2.30202443 |
| 55 | Constricted visual fields (HP:0001133) | 2.28575538 |
| 56 | Exercise intolerance (HP:0003546) | 2.28487268 |
| 57 | Respiratory failure (HP:0002878) | 2.22500001 |
| 58 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.21856788 |
| 59 | Hyperglycinemia (HP:0002154) | 2.21358495 |
| 60 | Lethargy (HP:0001254) | 2.20193745 |
| 61 | Type 2 muscle fiber atrophy (HP:0003554) | 2.18281350 |
| 62 | Hyperphosphaturia (HP:0003109) | 2.14224516 |
| 63 | Type II lissencephaly (HP:0007260) | 2.09720925 |
| 64 | Asplenia (HP:0001746) | 2.08085601 |
| 65 | Thyroiditis (HP:0100646) | 2.07912335 |
| 66 | Pancytopenia (HP:0001876) | 2.07680759 |
| 67 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.06492008 |
| 68 | Pallor (HP:0000980) | 2.04580428 |
| 69 | Increased IgM level (HP:0003496) | 2.04516147 |
| 70 | Pendular nystagmus (HP:0012043) | 2.02777384 |
| 71 | Nephronophthisis (HP:0000090) | 2.02615079 |
| 72 | Absent/shortened dynein arms (HP:0200106) | 2.01797684 |
| 73 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.01797684 |
| 74 | Methylmalonic aciduria (HP:0012120) | 2.00938639 |
| 75 | Leukodystrophy (HP:0002415) | 2.00874374 |
| 76 | Stomatitis (HP:0010280) | 2.00352192 |
| 77 | Muscle fiber atrophy (HP:0100295) | 1.94572037 |
| 78 | Type I transferrin isoform profile (HP:0003642) | 1.93829158 |
| 79 | Abnormal protein glycosylation (HP:0012346) | 1.93010856 |
| 80 | Abnormal glycosylation (HP:0012345) | 1.93010856 |
| 81 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93010856 |
| 82 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93010856 |
| 83 | Ketosis (HP:0001946) | 1.92438612 |
| 84 | Abnormality of the prostate (HP:0008775) | 1.91313936 |
| 85 | Generalized aminoaciduria (HP:0002909) | 1.89284661 |
| 86 | Hypoplasia of the uterus (HP:0000013) | 1.82421550 |
| 87 | Abnormality of T cells (HP:0002843) | 1.82072883 |
| 88 | Medial flaring of the eyebrow (HP:0010747) | 1.81496399 |
| 89 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.81330495 |
| 90 | Colon cancer (HP:0003003) | 1.81279893 |
| 91 | Stenosis of the external auditory canal (HP:0000402) | 1.79245442 |
| 92 | Sclerocornea (HP:0000647) | 1.78766833 |
| 93 | Agammaglobulinemia (HP:0004432) | 1.77385850 |
| 94 | Oral leukoplakia (HP:0002745) | 1.77380617 |
| 95 | Male pseudohermaphroditism (HP:0000037) | 1.75710293 |
| 96 | Cystic liver disease (HP:0006706) | 1.73115314 |
| 97 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.72097000 |
| 98 | Dicarboxylic aciduria (HP:0003215) | 1.72097000 |
| 99 | Renal cortical cysts (HP:0000803) | 1.71242185 |
| 100 | Abnormal biliary tract physiology (HP:0012439) | 1.70715986 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 3.65376847 |
| 2 | VRK2 | 3.55403961 |
| 3 | TXK | 3.19474755 |
| 4 | KDR | 3.02429325 |
| 5 | TESK2 | 2.98820210 |
| 6 | BCKDK | 2.93714221 |
| 7 | ZAK | 2.84481842 |
| 8 | TAOK3 | 2.54926976 |
| 9 | TLK1 | 2.51806938 |
| 10 | GRK1 | 2.50557683 |
| 11 | ADRBK2 | 2.27690440 |
| 12 | NUAK1 | 2.19578606 |
| 13 | MAP3K12 | 2.18814675 |
| 14 | VRK1 | 2.10665025 |
| 15 | MAP4K1 | 2.08380574 |
| 16 | MAP4K2 | 2.04318403 |
| 17 | STK16 | 1.98834208 |
| 18 | SCYL2 | 1.95951281 |
| 19 | MST4 | 1.80743688 |
| 20 | PBK | 1.79358937 |
| 21 | FRK | 1.64541193 |
| 22 | ITK | 1.46764812 |
| 23 | EIF2AK3 | 1.44605594 |
| 24 | TNIK | 1.42932205 |
| 25 | NLK | 1.40185897 |
| 26 | BMPR2 | 1.31547363 |
| 27 | BUB1 | 1.31238935 |
| 28 | PASK | 1.24176107 |
| 29 | CDC7 | 1.23094415 |
| 30 | WNK4 | 1.16349496 |
| 31 | GRK6 | 1.16272373 |
| 32 | DYRK2 | 1.16202103 |
| 33 | NME1 | 1.14605280 |
| 34 | TEC | 1.14207304 |
| 35 | DAPK1 | 1.11497136 |
| 36 | TAF1 | 1.10923669 |
| 37 | PRKCQ | 1.02333522 |
| 38 | SYK | 1.01082334 |
| 39 | BTK | 1.00489326 |
| 40 | PINK1 | 0.94817992 |
| 41 | BMPR1B | 0.93228071 |
| 42 | MYLK | 0.87612053 |
| 43 | WNK3 | 0.87476512 |
| 44 | CSNK1G1 | 0.85618470 |
| 45 | IKBKB | 0.85405189 |
| 46 | MUSK | 0.84561357 |
| 47 | LIMK1 | 0.84515791 |
| 48 | KIT | 0.83892175 |
| 49 | PIK3CG | 0.80468437 |
| 50 | RPS6KA4 | 0.78582651 |
| 51 | DAPK3 | 0.76744974 |
| 52 | INSRR | 0.76317227 |
| 53 | OXSR1 | 0.72680652 |
| 54 | LCK | 0.69837974 |
| 55 | TIE1 | 0.69613452 |
| 56 | PLK4 | 0.67254138 |
| 57 | RPS6KA5 | 0.66327741 |
| 58 | LYN | 0.63727102 |
| 59 | IKBKE | 0.63463312 |
| 60 | PLK3 | 0.61491137 |
| 61 | TNK2 | 0.59645472 |
| 62 | MAP3K11 | 0.58531599 |
| 63 | DAPK2 | 0.58183713 |
| 64 | FES | 0.58145458 |
| 65 | NME2 | 0.57165197 |
| 66 | CSNK2A2 | 0.56059359 |
| 67 | EIF2AK1 | 0.55551846 |
| 68 | ADRBK1 | 0.55352821 |
| 69 | FLT3 | 0.54152567 |
| 70 | CSF1R | 0.53087447 |
| 71 | OBSCN | 0.52647987 |
| 72 | PRKG2 | 0.52419810 |
| 73 | CSNK1G3 | 0.51726731 |
| 74 | MAP2K6 | 0.50604900 |
| 75 | TRIM28 | 0.48219927 |
| 76 | CDK3 | 0.46479165 |
| 77 | CSNK2A1 | 0.45091566 |
| 78 | MAP2K7 | 0.44619902 |
| 79 | AURKB | 0.42358225 |
| 80 | TESK1 | 0.42149899 |
| 81 | PIM1 | 0.41461860 |
| 82 | ATR | 0.41376191 |
| 83 | PLK1 | 0.40223695 |
| 84 | MAPKAPK3 | 0.37457346 |
| 85 | GRK7 | 0.37282473 |
| 86 | CSNK1G2 | 0.36923385 |
| 87 | STK39 | 0.36866501 |
| 88 | CLK1 | 0.36860258 |
| 89 | MKNK1 | 0.36237360 |
| 90 | PRKACA | 0.36087251 |
| 91 | MATK | 0.35952060 |
| 92 | MAP3K4 | 0.35575673 |
| 93 | PRKCA | 0.33687147 |
| 94 | SRPK1 | 0.32819126 |
| 95 | MAP3K5 | 0.32457197 |
| 96 | RPS6KB2 | 0.31326507 |
| 97 | MAPKAPK5 | 0.31156230 |
| 98 | HCK | 0.30131396 |
| 99 | PRKCG | 0.30025907 |
| 100 | ERBB3 | 0.28383150 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.52168686 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.22584272 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.92626329 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.29350923 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.73682549 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.63095610 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.58972920 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.54997078 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.44497390 |
| 10 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.33329536 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.17991148 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.17882074 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.13035782 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.06052024 |
| 15 | Protein export_Homo sapiens_hsa03060 | 1.90563984 |
| 16 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.87521522 |
| 17 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.85353377 |
| 18 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.80063549 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.79611760 |
| 20 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.75762461 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.69827752 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.65676690 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.63140686 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.58520093 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.55599748 |
| 26 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.47738453 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.39614024 |
| 28 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.39204934 |
| 29 | Mismatch repair_Homo sapiens_hsa03430 | 1.34310077 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.28997175 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.26450378 |
| 32 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.24794049 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.24418659 |
| 34 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.14864698 |
| 35 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.11450534 |
| 36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.07538055 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.02970942 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.01831000 |
| 39 | Basal transcription factors_Homo sapiens_hsa03022 | 1.00740511 |
| 40 | Peroxisome_Homo sapiens_hsa04146 | 0.98122139 |
| 41 | RNA transport_Homo sapiens_hsa03013 | 0.98047373 |
| 42 | Base excision repair_Homo sapiens_hsa03410 | 0.94703056 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.94238616 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.93396912 |
| 45 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.92374764 |
| 46 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.87414796 |
| 47 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.84700581 |
| 48 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.83068650 |
| 49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.81563192 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81253435 |
| 51 | Olfactory transduction_Homo sapiens_hsa04740 | 0.80781232 |
| 52 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.79437010 |
| 53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.76075284 |
| 54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.72308736 |
| 55 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.69783613 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67381512 |
| 57 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.67336810 |
| 58 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.63209290 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.62878459 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62520200 |
| 61 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.62290536 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.61647394 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60776171 |
| 64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.60191813 |
| 65 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.59184851 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.58524567 |
| 67 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.57403682 |
| 68 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.57357098 |
| 69 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.55887198 |
| 70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.54205281 |
| 71 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.53847798 |
| 72 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.49891527 |
| 73 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.46910584 |
| 74 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.46058655 |
| 75 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.45142399 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.43417567 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.42828406 |
| 78 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.42551132 |
| 79 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.42426215 |
| 80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.41637346 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.41602028 |
| 82 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.40947179 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.36717522 |
| 84 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.36263702 |
| 85 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.35762943 |
| 86 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.35530999 |
| 87 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.35105052 |
| 88 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.34792950 |
| 89 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.34410597 |
| 90 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.33962626 |
| 91 | Measles_Homo sapiens_hsa05162 | 0.30913529 |
| 92 | Leishmaniasis_Homo sapiens_hsa05140 | 0.25880145 |
| 93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.23443312 |
| 94 | Nicotine addiction_Homo sapiens_hsa05033 | 0.23153102 |
| 95 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.23118374 |
| 96 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.20406644 |
| 97 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.17298642 |
| 98 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.14884493 |
| 99 | Salivary secretion_Homo sapiens_hsa04970 | 0.14548400 |
| 100 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.13776869 |

