RPSAP51

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA integration (GO:0015074)6.25081784
2alkaloid metabolic process (GO:0009820)6.01459754
3retinal cone cell development (GO:0046549)5.86120902
4xenobiotic catabolic process (GO:0042178)5.64314086
5dopamine biosynthetic process (GO:0042416)5.09335360
6tyrosine metabolic process (GO:0006570)5.08534634
7benzene-containing compound metabolic process (GO:0042537)4.59213386
8neural tube formation (GO:0001841)4.59044835
9response to insecticide (GO:0017085)4.54432039
10phenylpropanoid metabolic process (GO:0009698)4.54146260
11presynaptic membrane assembly (GO:0097105)4.34277084
12protein localization to cilium (GO:0061512)4.17403765
13regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)4.02357412
14positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)4.02357412
15cellular response to zinc ion (GO:0071294)3.98472072
16neuron recognition (GO:0008038)3.97328141
17positive regulation of dendritic spine morphogenesis (GO:0061003)3.91776590
18synaptic transmission, dopaminergic (GO:0001963)3.88927303
19phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)3.80656764
20positive regulation of male gonad development (GO:2000020)3.76939059
21axonal fasciculation (GO:0007413)3.76804387
22regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139)3.72466217
23positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141)3.72466217
24signal peptide processing (GO:0006465)3.71488997
25negative regulation of calcium ion-dependent exocytosis (GO:0045955)3.68644036
26synaptic transmission, cholinergic (GO:0007271)3.66653064
27catecholamine biosynthetic process (GO:0042423)3.65451200
28catechol-containing compound biosynthetic process (GO:0009713)3.65451200
29G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071993.64235559
30positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.61389964
31regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.61389964
32protein heterotetramerization (GO:0051290)3.61325556
33norepinephrine metabolic process (GO:0042415)3.51115271
34eye photoreceptor cell development (GO:0042462)3.44170204
35positive regulation of vesicle fusion (GO:0031340)3.42879044
36microtubule severing (GO:0051013)3.38324929
37presynaptic membrane organization (GO:0097090)3.37813319
38metanephric mesenchyme development (GO:0072075)3.36466722
39multicellular organismal aging (GO:0010259)3.35762440
40replication fork processing (GO:0031297)3.33542510
41magnesium ion transport (GO:0015693)3.30923443
42cellular response to nicotine (GO:0071316)3.26960956
43Golgi to endosome transport (GO:0006895)3.25855074
44photoreceptor cell development (GO:0042461)3.25400933
45neuron cell-cell adhesion (GO:0007158)3.24134621
46toxin metabolic process (GO:0009404)3.18367498
47male sex determination (GO:0030238)3.13982386
48intraciliary transport (GO:0042073)3.10901983
49prostate gland growth (GO:0060736)3.10504733
50spinal cord motor neuron differentiation (GO:0021522)3.08738314
51pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.07830960
52regulation of male gonad development (GO:2000018)3.06888553
53vocalization behavior (GO:0071625)3.06626292
54response to water (GO:0009415)3.06237921
55positive regulation of mRNA processing (GO:0050685)3.03302222
56C4-dicarboxylate transport (GO:0015740)2.99906289
57dendritic spine morphogenesis (GO:0060997)2.99735665
58negative regulation of complement activation (GO:0045916)2.96981892
59positive regulation of mRNA 3-end processing (GO:0031442)2.94352731
60lipopolysaccharide biosynthetic process (GO:0009103)2.90831839
61postsynaptic membrane organization (GO:0001941)2.89674247
62establishment of mitochondrion localization (GO:0051654)2.88687048
63membrane assembly (GO:0071709)2.87687029
64maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.86458903
65synapse assembly (GO:0007416)2.85410781
66regulation of cAMP-dependent protein kinase activity (GO:2000479)2.84470377
67peripheral nervous system neuron development (GO:0048935)2.83945081
68positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.83625687
69pyrimidine nucleotide catabolic process (GO:0006244)2.83190167
70regulation of telomere maintenance (GO:0032204)2.82488126
71rRNA methylation (GO:0031167)2.81898712
72rRNA modification (GO:0000154)2.81357450
73regulation of mRNA 3-end processing (GO:0031440)2.80418904
74behavioral response to nicotine (GO:0035095)2.77767872
75sex differentiation (GO:0007548)2.76828767
76positive regulation of cell size (GO:0045793)2.75336932
77somite development (GO:0061053)2.73859577
78microtubule depolymerization (GO:0007019)2.72517392
79kidney mesenchyme development (GO:0072074)2.71858430
80pseudouridine synthesis (GO:0001522)2.63818894
81dopamine metabolic process (GO:0042417)2.63222777
82base-excision repair, AP site formation (GO:0006285)2.62071467
83proximal/distal pattern formation (GO:0009954)2.62003497
84interkinetic nuclear migration (GO:0022027)2.61639529
85retinal ganglion cell axon guidance (GO:0031290)2.61327102
86response to zinc ion (GO:0010043)2.60113159
87regulation of dendritic spine morphogenesis (GO:0061001)2.59941820
88microtubule polymerization or depolymerization (GO:0031109)2.59935664
89pharyngeal system development (GO:0060037)2.59195385
90regulation of collateral sprouting (GO:0048670)2.56609640
91central nervous system projection neuron axonogenesis (GO:0021952)2.55722441
92protein localization to synapse (GO:0035418)2.55050365
93negative regulation of protein activation cascade (GO:2000258)2.54849518
94positive regulation of dendritic spine development (GO:0060999)2.54663062
95negative regulation of protein localization to cell surface (GO:2000009)2.53296598
96prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060522.52783361
97monoubiquitinated protein deubiquitination (GO:0035520)2.51425677
98positive regulation of mRNA catabolic process (GO:0061014)2.50895152
99regulation of synapse structural plasticity (GO:0051823)2.50678042
100intraspecies interaction between organisms (GO:0051703)2.49754455

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.83905096
2IGF1R_20145208_ChIP-Seq_DFB_Human3.53529587
3GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse3.34779966
4GBX2_23144817_ChIP-Seq_PC3_Human3.32732601
5ZNF274_21170338_ChIP-Seq_K562_Hela3.31055123
6VDR_22108803_ChIP-Seq_LS180_Human3.27984523
7POU3F2_20337985_ChIP-ChIP_501MEL_Human3.10310335
8ZFP57_27257070_Chip-Seq_ESCs_Mouse3.00074686
9CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.73657113
10FUS_26573619_Chip-Seq_HEK293_Human2.64156258
11CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.44295217
12TAF15_26573619_Chip-Seq_HEK293_Human2.42205492
13CTBP2_25329375_ChIP-Seq_LNCAP_Human2.31448354
14AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human2.30788687
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.25941445
16FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.25682821
17SALL1_21062744_ChIP-ChIP_HESCs_Human2.24533983
18AR_21572438_ChIP-Seq_LNCaP_Human2.22957119
19SMAD_19615063_ChIP-ChIP_OVARY_Human2.15561597
20CTBP1_25329375_ChIP-Seq_LNCAP_Human2.12398957
21P300_19829295_ChIP-Seq_ESCs_Human2.12358146
22BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.10221747
23POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.02994958
24TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.02994958
25EZH2_22144423_ChIP-Seq_EOC_Human2.02643493
26EWS_26573619_Chip-Seq_HEK293_Human1.91769368
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.84146006
28UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.77149694
29ER_23166858_ChIP-Seq_MCF-7_Human1.74274702
30TOP2B_26459242_ChIP-Seq_MCF-7_Human1.73676374
31OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.72466436
32STAT3_23295773_ChIP-Seq_U87_Human1.70937397
33BCAT_22108803_ChIP-Seq_LS180_Human1.68281156
34SMAD4_21799915_ChIP-Seq_A2780_Human1.67502868
35PIAS1_25552417_ChIP-Seq_VCAP_Human1.64391201
36NOTCH1_21737748_ChIP-Seq_TLL_Human1.64216587
37SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.63050993
38MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.59328285
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.56468178
40MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.56159587
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.54772195
42SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.53010259
43GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.52127914
44SMAD3_21741376_ChIP-Seq_EPCs_Human1.50280833
45TCF4_23295773_ChIP-Seq_U87_Human1.48412054
46AR_25329375_ChIP-Seq_VCAP_Human1.47276448
47PCGF2_27294783_Chip-Seq_ESCs_Mouse1.46878126
48ELK1_19687146_ChIP-ChIP_HELA_Human1.46404521
49RNF2_27304074_Chip-Seq_NSC_Mouse1.41822557
50NR3C1_21868756_ChIP-Seq_MCF10A_Human1.40332123
51EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.40140067
52TCF4_22108803_ChIP-Seq_LS180_Human1.39358476
53EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.33629228
54RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.30434334
55RUNX2_22187159_ChIP-Seq_PCA_Human1.29541942
56TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.29091325
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.26035254
58TP63_19390658_ChIP-ChIP_HaCaT_Human1.25681412
59BMI1_23680149_ChIP-Seq_NPCS_Mouse1.23923527
60KLF5_20875108_ChIP-Seq_MESCs_Mouse1.23905030
61SUZ12_27294783_Chip-Seq_NPCs_Mouse1.23439124
62HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.21365868
63MYC_18940864_ChIP-ChIP_HL60_Human1.18987005
64CDX2_22108803_ChIP-Seq_LS180_Human1.18961072
65RXR_22108803_ChIP-Seq_LS180_Human1.18914035
66CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.15629021
67RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.14535020
68NRF2_20460467_ChIP-Seq_MEFs_Mouse1.13961974
69NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.13961974
70SMAD4_21741376_ChIP-Seq_EPCs_Human1.13016596
71PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.11732460
72SOX2_19829295_ChIP-Seq_ESCs_Human1.11191801
73NANOG_19829295_ChIP-Seq_ESCs_Human1.11191801
74IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10752858
75CBP_20019798_ChIP-Seq_JUKART_Human1.10752858
76REST_21632747_ChIP-Seq_MESCs_Mouse1.10015462
77SOX2_21211035_ChIP-Seq_LN229_Gbm1.09165591
78TAL1_26923725_Chip-Seq_HPCs_Mouse1.07263127
79KDM2B_26808549_Chip-Seq_REH_Human1.07222816
80PCGF2_27294783_Chip-Seq_NPCs_Mouse1.06861671
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.05882970
82FOXM1_26456572_ChIP-Seq_MCF-7_Human1.05351000
83P53_22387025_ChIP-Seq_ESCs_Mouse1.04746961
84SOX9_26525672_Chip-Seq_HEART_Mouse1.04528851
85AUTS2_25519132_ChIP-Seq_293T-REX_Human1.03723289
86EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.03699427
87ARNT_22903824_ChIP-Seq_MCF-7_Human1.02912313
88IRF1_19129219_ChIP-ChIP_H3396_Human1.01902873
89EZH2_27294783_Chip-Seq_NPCs_Mouse1.01899335
90CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01008973
91TP53_22573176_ChIP-Seq_HFKS_Human0.99681317
92TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99149191
93SUZ12_18555785_Chip-Seq_ESCs_Mouse0.95448542
94NFE2_27457419_Chip-Seq_LIVER_Mouse0.94139557
95CBX2_27304074_Chip-Seq_ESCs_Mouse0.93445648
96E2F1_18555785_Chip-Seq_ESCs_Mouse0.93428716
97P300_18555785_Chip-Seq_ESCs_Mouse0.92949941
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.92927206
99AHR_22903824_ChIP-Seq_MCF-7_Human0.92647692
100ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92595232

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.40345669
2MP0000569_abnormal_digit_pigmentation3.46013066
3MP0004133_heterotaxia2.75949849
4MP0000013_abnormal_adipose_tissue2.71574814
5MP0002638_abnormal_pupillary_reflex2.70478186
6MP0005423_abnormal_somatic_nervous2.48064915
7MP0005171_absent_coat_pigmentation2.47741982
8MP0002736_abnormal_nociception_after2.45280213
9MP0002102_abnormal_ear_morphology2.33044480
10MP0003283_abnormal_digestive_organ2.29182353
11MP0001299_abnormal_eye_distance/2.27664687
12MP0000049_abnormal_middle_ear2.14669773
13MP0002938_white_spotting2.13502285
14MP0009384_cardiac_valve_regurgitation2.11150478
15MP0000566_synostosis2.06055983
16MP0000372_irregular_coat_pigmentation2.01705724
17MP0005253_abnormal_eye_physiology1.99366910
18MP0001529_abnormal_vocalization1.98917445
19MP0003787_abnormal_imprinting1.96323677
20MP0005551_abnormal_eye_electrophysiolog1.95158031
21MP0000427_abnormal_hair_cycle1.92575554
22MP0000383_abnormal_hair_follicle1.91148773
23MP0009697_abnormal_copulation1.89347944
24MP0001968_abnormal_touch/_nociception1.86672098
25MP0003136_yellow_coat_color1.80429922
26MP0008058_abnormal_DNA_repair1.75628307
27MP0003937_abnormal_limbs/digits/tail_de1.74562917
28MP0006072_abnormal_retinal_apoptosis1.74051046
29MP0000579_abnormal_nail_morphology1.72921400
30MP0002009_preneoplasia1.70411757
31MP0003718_maternal_effect1.68782523
32MP0005174_abnormal_tail_pigmentation1.61129463
33MP0004885_abnormal_endolymph1.55280129
34MP0002234_abnormal_pharynx_morphology1.50439720
35MP0004859_abnormal_synaptic_plasticity1.36053057
36MP0001502_abnormal_circadian_rhythm1.33936389
37MP0003567_abnormal_fetal_cardiomyocyte1.32594980
38MP0000778_abnormal_nervous_system1.29122782
39MP0001905_abnormal_dopamine_level1.27311724
40MP0010678_abnormal_skin_adnexa1.26367510
41MP0002095_abnormal_skin_pigmentation1.23161137
42MP0001984_abnormal_olfaction1.19751262
43MP0000516_abnormal_urinary_system1.19410454
44MP0005367_renal/urinary_system_phenotyp1.19410454
45MP0009250_abnormal_appendicular_skeleto1.16496374
46MP0001486_abnormal_startle_reflex1.15889563
47MP0003935_abnormal_craniofacial_develop1.14975539
48MP0009745_abnormal_behavioral_response1.11709128
49MP0003635_abnormal_synaptic_transmissio1.11242930
50MP0005395_other_phenotype1.10493630
51MP0001188_hyperpigmentation1.10452443
52MP0000631_abnormal_neuroendocrine_gland1.08875144
53MP0000955_abnormal_spinal_cord1.07749527
54MP0004924_abnormal_behavior1.05798008
55MP0005386_behavior/neurological_phenoty1.05798008
56MP0005379_endocrine/exocrine_gland_phen1.04285283
57MP0003698_abnormal_male_reproductive1.02911398
58MP0002177_abnormal_outer_ear1.01737746
59MP0002752_abnormal_somatic_nervous0.98166867
60MP0005503_abnormal_tendon_morphology0.97295492
61MP0005075_abnormal_melanosome_morpholog0.96067817
62MP0001324_abnormal_eye_pigmentation0.96004177
63MP0001929_abnormal_gametogenesis0.95829707
64MP0002272_abnormal_nervous_system0.95763601
65MP0003252_abnormal_bile_duct0.89698243
66MP0003943_abnormal_hepatobiliary_system0.88080224
67MP0002067_abnormal_sensory_capabilities0.87931949
68MP0005646_abnormal_pituitary_gland0.87854963
69MP0002233_abnormal_nose_morphology0.85690183
70MP0000647_abnormal_sebaceous_gland0.85541915
71MP0002210_abnormal_sex_determination0.85371957
72MP0003828_pulmonary_edema0.85021671
73MP0003638_abnormal_response/metabolism_0.84228452
74MP0003936_abnormal_reproductive_system0.83547101
75MP0005195_abnormal_posterior_eye0.82943494
76MP0002160_abnormal_reproductive_system0.81269858
77MP0008877_abnormal_DNA_methylation0.80562101
78MP0000026_abnormal_inner_ear0.80487098
79MP0002882_abnormal_neuron_morphology0.80467608
80MP0008789_abnormal_olfactory_epithelium0.80297249
81MP0003122_maternal_imprinting0.78874685
82MP0005220_abnormal_exocrine_pancreas0.78424679
83MP0002932_abnormal_joint_morphology0.77601726
84MP0002168_other_aberrant_phenotype0.76293693
85MP0002572_abnormal_emotion/affect_behav0.75816584
86MP0002109_abnormal_limb_morphology0.75377943
87MP0002751_abnormal_autonomic_nervous0.74317576
88MP0004142_abnormal_muscle_tone0.74299033
89MP0003755_abnormal_palate_morphology0.73900744
90MP0002063_abnormal_learning/memory/cond0.72558446
91MP0003137_abnormal_impulse_conducting0.71443964
92MP0000653_abnormal_sex_gland0.71344899
93MP0003121_genomic_imprinting0.70606238
94MP0001145_abnormal_male_reproductive0.69999306
95MP0000470_abnormal_stomach_morphology0.65808509
96MP0001293_anophthalmia0.65794975
97MP0003861_abnormal_nervous_system0.65520909
98MP0002152_abnormal_brain_morphology0.64989421
99MP0002734_abnormal_mechanical_nocicepti0.64706679
100MP0003890_abnormal_embryonic-extraembry0.64422518

Predicted human phenotypes

RankGene SetZ-score
1Insidious onset (HP:0003587)4.16945164
2Termporal pattern (HP:0011008)4.16945164
3True hermaphroditism (HP:0010459)4.12480913
4Degeneration of the lateral corticospinal tracts (HP:0002314)3.93698668
5Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.93698668
6Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.92991510
7Hypokinesia (HP:0002375)3.87054148
8Limb dystonia (HP:0002451)3.84688644
9Neonatal respiratory distress (HP:0002643)3.79303324
10Acute lymphatic leukemia (HP:0006721)3.40899553
11Broad-based gait (HP:0002136)3.14572849
12Abnormality of the corticospinal tract (HP:0002492)3.08173556
13Gait imbalance (HP:0002141)2.98803707
14Impaired vibration sensation in the lower limbs (HP:0002166)2.88017444
15Atonic seizures (HP:0010819)2.87760413
16Disinhibition (HP:0000734)2.79327035
17Abnormality of midbrain morphology (HP:0002418)2.79210757
18Molar tooth sign on MRI (HP:0002419)2.79210757
19Abnormal sex determination (HP:0012244)2.74435845
20Sex reversal (HP:0012245)2.74435845
21Diminished movement (HP:0002374)2.72019799
22Genetic anticipation (HP:0003743)2.71588422
23Amyotrophic lateral sclerosis (HP:0007354)2.69330798
24Abolished electroretinogram (ERG) (HP:0000550)2.68328068
25Focal seizures (HP:0007359)2.65633722
26Medial flaring of the eyebrow (HP:0010747)2.65173931
27Hyperventilation (HP:0002883)2.57943893
28Agitation (HP:0000713)2.56443052
29Neoplasm of the heart (HP:0100544)2.54157284
30Congenital primary aphakia (HP:0007707)2.51796679
31Aplasia/Hypoplasia of the tibia (HP:0005772)2.50124504
32Inappropriate behavior (HP:0000719)2.44725256
33Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.44402597
34Nephronophthisis (HP:0000090)2.42669281
35Congenital stationary night blindness (HP:0007642)2.40882789
36Status epilepticus (HP:0002133)2.40392006
37Birth length less than 3rd percentile (HP:0003561)2.29212968
38Broad foot (HP:0001769)2.28572063
39Bilateral microphthalmos (HP:0007633)2.27583661
40Median cleft lip (HP:0000161)2.26371842
41Bulbous nose (HP:0000414)2.25580022
42Pancreatic fibrosis (HP:0100732)2.24814734
43Febrile seizures (HP:0002373)2.24022699
44Patellar aplasia (HP:0006443)2.23329480
45Large earlobe (HP:0009748)2.23110712
46Abnormality of the phalanges of the 2nd finger (HP:0009541)2.20267218
47Follicular hyperkeratosis (HP:0007502)2.16647406
48Nephrogenic diabetes insipidus (HP:0009806)2.12400698
49Aplasia/Hypoplasia of the patella (HP:0006498)2.12196033
50Urinary bladder sphincter dysfunction (HP:0002839)2.11248540
51Absent speech (HP:0001344)2.07075317
52Focal motor seizures (HP:0011153)2.04416669
53Dialeptic seizures (HP:0011146)2.03227394
54Slow-growing hair (HP:0002217)2.02617383
55Abnormality of hair growth rate (HP:0011363)2.02617383
56Abnormality of the parietal bone (HP:0002696)2.02554265
57Biliary tract neoplasm (HP:0100574)2.02451715
58Abnormality of the labia minora (HP:0012880)2.02266902
59Failure to thrive in infancy (HP:0001531)2.01985251
60Polyphagia (HP:0002591)2.00985576
61Genital tract atresia (HP:0001827)1.99386120
62Pancreatic cysts (HP:0001737)1.96930531
63Limb hypertonia (HP:0002509)1.95679625
64Urinary urgency (HP:0000012)1.95191559
65Long nose (HP:0003189)1.94985314
66Abnormal number of incisors (HP:0011064)1.92878538
67Congenital, generalized hypertrichosis (HP:0004540)1.92374025
68Short humerus (HP:0005792)1.92053554
69Cupped ear (HP:0000378)1.91943235
70Colon cancer (HP:0003003)1.91012034
71Mask-like facies (HP:0000298)1.90611585
72Thyroid-stimulating hormone excess (HP:0002925)1.90237237
73Hemiparesis (HP:0001269)1.87849205
74Aplasia/hypoplasia of the humerus (HP:0006507)1.86055930
75Male pseudohermaphroditism (HP:0000037)1.85876773
76Hypothermia (HP:0002045)1.85641350
77Short tibia (HP:0005736)1.85478779
78Conical tooth (HP:0000698)1.83799939
79Tubulointerstitial nephritis (HP:0001970)1.83005967
80Vaginal atresia (HP:0000148)1.82618497
81Preaxial foot polydactyly (HP:0001841)1.82376156
82Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82313517
83Abnormality of alanine metabolism (HP:0010916)1.82313517
84Hyperalaninemia (HP:0003348)1.82313517
85Epileptic encephalopathy (HP:0200134)1.79216017
86Meningioma (HP:0002858)1.78571016
87Gonadal dysgenesis (HP:0000133)1.77505486
88Abnormality of the renal medulla (HP:0100957)1.76988712
89Hyperglycinuria (HP:0003108)1.75278794
90Cerebellar dysplasia (HP:0007033)1.73540799
91Postaxial hand polydactyly (HP:0001162)1.71422519
92Drooling (HP:0002307)1.71063150
93Poor coordination (HP:0002370)1.70730496
94Intestinal atresia (HP:0011100)1.69432020
95Chronic bronchitis (HP:0004469)1.68916016
96Nephroblastoma (Wilms tumor) (HP:0002667)1.68620440
97Atrophy/Degeneration involving motor neurons (HP:0007373)1.66601524
98Subaortic stenosis (HP:0001682)1.66529545
99Abnormality of the left ventricular outflow tract (HP:0011103)1.66529545
100Testicular neoplasm (HP:0010788)1.65599446

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MKNK23.57566332
2TNIK3.55986051
3LATS13.17669667
4FRK3.09715087
5BCKDK2.87065065
6EPHA32.83431542
7MAP2K72.78669530
8MAP3K42.65366797
9MKNK12.64186823
10PDK22.57038263
11NUAK12.51298651
12DYRK32.50986301
13TAOK32.45081349
14MARK12.33537312
15MAPKAPK52.30175999
16CAMKK22.23057857
17ERBB32.20756491
18CASK2.18424112
19PINK12.10072122
20BRSK22.03686745
21PNCK1.92680775
22PIK3CG1.72164809
23WNK31.66343091
24IRAK11.55182826
25CCNB11.52558010
26TRIM281.48437265
27AKT31.47892462
28SIK21.42646414
29BUB11.41187752
30ADRBK21.21353066
31BMPR1B1.20660008
32BCR1.20173788
33MAP2K41.19829878
34MAPK131.18471871
35CAMK2B1.11402492
36BRD41.07740018
37DAPK21.04673494
38SGK21.00538620
39CSNK1G30.98417458
40DYRK20.95420917
41BRSK10.94829160
42CSNK1G20.94097029
43TAF10.92293704
44MST40.84836466
45WNK40.82596569
46CAMKK10.81678973
47RPS6KA50.79295879
48PBK0.79136099
49CSNK1G10.78250774
50PLK40.76067716
51STK38L0.73928428
52ACVR1B0.72246086
53GRK10.72031532
54CAMK2A0.65812150
55NEK10.65389379
56PHKG10.62843988
57PHKG20.62843988
58SGK4940.61597234
59SGK2230.61597234
60PKN10.61486380
61RPS6KA40.59751236
62CDC70.59673812
63ZAK0.57762179
64DYRK1A0.57390786
65MAP4K20.56020688
66PRKCH0.55587898
67STK30.54506152
68STK390.54188138
69ADRBK10.52569315
70NEK60.51606273
71EPHA40.50311563
72PRKCG0.47163925
73NTRK20.42780353
74FGFR10.41945449
75INSRR0.41549796
76CDK180.41205607
77PAK30.41061632
78PRKG10.40826774
79CDK90.39677540
80PRKCE0.39619014
81IRAK20.39494638
82MELK0.38419242
83CDK150.38182867
84CSNK1A1L0.37900666
85CAMK2D0.37108511
86GSK3A0.36000103
87CDK50.35784117
88MARK20.35733760
89MAP3K60.35374340
90CDK11A0.33836470
91MAP3K120.33775208
92NEK20.33567106
93PRKACA0.31529079
94CDK140.31433275
95TRPM70.30657390
96PRKACB0.29525737
97SGK30.29186729
98CHEK20.29064773
99RPS6KA20.28223688
100MAP3K50.27994025

Predicted pathways (KEGG)

RankGene SetZ-score
1Basal transcription factors_Homo sapiens_hsa030222.79449430
2Protein export_Homo sapiens_hsa030602.69228002
3Cocaine addiction_Homo sapiens_hsa050302.67522950
4Propanoate metabolism_Homo sapiens_hsa006402.32707265
5Nicotine addiction_Homo sapiens_hsa050332.29069267
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.14915837
7beta-Alanine metabolism_Homo sapiens_hsa004102.12352032
8One carbon pool by folate_Homo sapiens_hsa006702.11631069
9Histidine metabolism_Homo sapiens_hsa003402.02126800
10Nitrogen metabolism_Homo sapiens_hsa009101.98939461
11Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.87778057
12Basal cell carcinoma_Homo sapiens_hsa052171.86092697
13Butanoate metabolism_Homo sapiens_hsa006501.85196635
14Olfactory transduction_Homo sapiens_hsa047401.82204146
15Phototransduction_Homo sapiens_hsa047441.80622869
16Amphetamine addiction_Homo sapiens_hsa050311.77365610
17Tryptophan metabolism_Homo sapiens_hsa003801.71098148
18Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.64662717
19Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.63238246
20Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.60534671
21Selenocompound metabolism_Homo sapiens_hsa004501.60433193
22Tyrosine metabolism_Homo sapiens_hsa003501.56444715
23Taste transduction_Homo sapiens_hsa047421.50291709
24Ether lipid metabolism_Homo sapiens_hsa005651.50057005
25Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.47392748
26Fatty acid biosynthesis_Homo sapiens_hsa000611.36971348
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.36569655
28Homologous recombination_Homo sapiens_hsa034401.33223630
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.31594784
30Fanconi anemia pathway_Homo sapiens_hsa034601.31587553
31Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.31270113
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.28052165
33Glycerolipid metabolism_Homo sapiens_hsa005611.25701017
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.25593330
35Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.24655421
36ABC transporters_Homo sapiens_hsa020101.23820028
37Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.22561965
38Hedgehog signaling pathway_Homo sapiens_hsa043401.22256416
39Fatty acid degradation_Homo sapiens_hsa000711.20878695
40Long-term depression_Homo sapiens_hsa047301.15644228
41Pyruvate metabolism_Homo sapiens_hsa006201.15171691
42Mineral absorption_Homo sapiens_hsa049781.14591769
43Dopaminergic synapse_Homo sapiens_hsa047281.14027401
44Circadian rhythm_Homo sapiens_hsa047101.09382716
45Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.09034586
46Circadian entrainment_Homo sapiens_hsa047131.08869210
47Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.94838166
48Arginine and proline metabolism_Homo sapiens_hsa003300.94185610
49Parkinsons disease_Homo sapiens_hsa050120.94002106
50Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.88617671
51alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.88418117
52cAMP signaling pathway_Homo sapiens_hsa040240.87587207
53Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.85185819
54Linoleic acid metabolism_Homo sapiens_hsa005910.84910190
55Hippo signaling pathway_Homo sapiens_hsa043900.82386387
56Renin secretion_Homo sapiens_hsa049240.81606036
57Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.80547212
58Chemical carcinogenesis_Homo sapiens_hsa052040.80274479
59Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.80095829
60Peroxisome_Homo sapiens_hsa041460.73378461
61RNA degradation_Homo sapiens_hsa030180.72714604
62Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.72352125
63Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70637464
64Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.69726030
65Huntingtons disease_Homo sapiens_hsa050160.68870705
66Longevity regulating pathway - mammal_Homo sapiens_hsa042110.64198061
67Morphine addiction_Homo sapiens_hsa050320.63686255
68Melanoma_Homo sapiens_hsa052180.62273367
69Glutamatergic synapse_Homo sapiens_hsa047240.61722148
70RNA transport_Homo sapiens_hsa030130.61453351
71Alcoholism_Homo sapiens_hsa050340.60884122
72Inositol phosphate metabolism_Homo sapiens_hsa005620.60663331
73Oxytocin signaling pathway_Homo sapiens_hsa049210.58737759
74Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.57068677
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56434836
76Serotonergic synapse_Homo sapiens_hsa047260.54643561
77Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.54425284
78Retinol metabolism_Homo sapiens_hsa008300.54181597
79TGF-beta signaling pathway_Homo sapiens_hsa043500.54046363
80Cholinergic synapse_Homo sapiens_hsa047250.53270100
81Fatty acid metabolism_Homo sapiens_hsa012120.51930608
82Oxidative phosphorylation_Homo sapiens_hsa001900.51887588
83Steroid hormone biosynthesis_Homo sapiens_hsa001400.50475974
84Melanogenesis_Homo sapiens_hsa049160.50374572
85Purine metabolism_Homo sapiens_hsa002300.49781124
86GABAergic synapse_Homo sapiens_hsa047270.48237962
87Glycerophospholipid metabolism_Homo sapiens_hsa005640.47590193
88Salivary secretion_Homo sapiens_hsa049700.45589094
89Phosphatidylinositol signaling system_Homo sapiens_hsa040700.45440744
90Metabolic pathways_Homo sapiens_hsa011000.45294621
91Non-homologous end-joining_Homo sapiens_hsa034500.44595282
92RNA polymerase_Homo sapiens_hsa030200.44525300
93FoxO signaling pathway_Homo sapiens_hsa040680.42786465
94Insulin secretion_Homo sapiens_hsa049110.40786944
95Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.40668091
96Axon guidance_Homo sapiens_hsa043600.39424036
97Wnt signaling pathway_Homo sapiens_hsa043100.39142906
98p53 signaling pathway_Homo sapiens_hsa041150.37966577
99cGMP-PKG signaling pathway_Homo sapiens_hsa040220.37829686
100Regulation of autophagy_Homo sapiens_hsa041400.37174374

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