

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | * ribosomal small subunit assembly (GO:0000028) | 5.46805852 |
| 2 | DNA deamination (GO:0045006) | 4.48026105 |
| 3 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.33071266 |
| 4 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.33071266 |
| 5 | NADH dehydrogenase complex assembly (GO:0010257) | 4.33071266 |
| 6 | respiratory chain complex IV assembly (GO:0008535) | 4.16461366 |
| 7 | protein complex biogenesis (GO:0070271) | 4.08170523 |
| 8 | replication fork processing (GO:0031297) | 4.03113710 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 3.96963014 |
| 10 | chromatin remodeling at centromere (GO:0031055) | 3.94747542 |
| 11 | base-excision repair, AP site formation (GO:0006285) | 3.85591829 |
| 12 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.84457831 |
| 13 | CENP-A containing nucleosome assembly (GO:0034080) | 3.82380934 |
| 14 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.79838310 |
| 15 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.74724990 |
| 16 | viral transcription (GO:0019083) | 3.71556533 |
| 17 | translational termination (GO:0006415) | 3.67440792 |
| 18 | response to pheromone (GO:0019236) | 3.64676890 |
| 19 | cytochrome complex assembly (GO:0017004) | 3.63424396 |
| 20 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.60353916 |
| 21 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.57370221 |
| 22 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.54679262 |
| 23 | termination of RNA polymerase III transcription (GO:0006386) | 3.54679262 |
| 24 | DNA double-strand break processing (GO:0000729) | 3.46663875 |
| 25 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.44094627 |
| 26 | ATP synthesis coupled proton transport (GO:0015986) | 3.44094627 |
| 27 | translational elongation (GO:0006414) | 3.40076248 |
| 28 | positive regulation of cell size (GO:0045793) | 3.39235428 |
| 29 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.37001053 |
| 30 | platelet dense granule organization (GO:0060155) | 3.36891856 |
| 31 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.36783136 |
| 32 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.34131364 |
| 33 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.34131364 |
| 34 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.33539325 |
| 35 | cotranslational protein targeting to membrane (GO:0006613) | 3.32016525 |
| 36 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.29238216 |
| 37 | regulation of mitochondrial translation (GO:0070129) | 3.26731189 |
| 38 | ribosomal large subunit biogenesis (GO:0042273) | 3.26210603 |
| 39 | protein targeting to ER (GO:0045047) | 3.25606986 |
| 40 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.24077773 |
| 41 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.23915737 |
| 42 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.22723186 |
| 43 | proteasome assembly (GO:0043248) | 3.22654379 |
| 44 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.22630345 |
| 45 | histone exchange (GO:0043486) | 3.16617476 |
| 46 | synapsis (GO:0007129) | 3.14743942 |
| 47 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.14102690 |
| 48 | CTP biosynthetic process (GO:0006241) | 3.12297436 |
| 49 | CTP metabolic process (GO:0046036) | 3.12297436 |
| 50 | protein-cofactor linkage (GO:0018065) | 3.12073510 |
| 51 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.10881579 |
| 52 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.10260105 |
| 53 | formation of translation preinitiation complex (GO:0001731) | 3.08511818 |
| 54 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.08485157 |
| 55 | DNA strand renaturation (GO:0000733) | 3.08146110 |
| 56 | protein localization to endoplasmic reticulum (GO:0070972) | 3.07683340 |
| 57 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.07318781 |
| 58 | ribosomal small subunit biogenesis (GO:0042274) | 3.05760616 |
| 59 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.97477283 |
| 60 | deoxyribonucleotide catabolic process (GO:0009264) | 2.97298568 |
| 61 | maturation of SSU-rRNA (GO:0030490) | 2.96261788 |
| 62 | arginine catabolic process (GO:0006527) | 2.95226731 |
| 63 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.95077948 |
| 64 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.94159511 |
| 65 | resolution of meiotic recombination intermediates (GO:0000712) | 2.93662470 |
| 66 | deoxyribose phosphate catabolic process (GO:0046386) | 2.92858494 |
| 67 | translational initiation (GO:0006413) | 2.91798702 |
| 68 | regulation of protein glycosylation (GO:0060049) | 2.91042959 |
| 69 | respiratory electron transport chain (GO:0022904) | 2.90541811 |
| 70 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.90444649 |
| 71 | cellular component biogenesis (GO:0044085) | 2.88940663 |
| 72 | behavioral response to nicotine (GO:0035095) | 2.85576083 |
| 73 | myoblast migration (GO:0051451) | 2.85179264 |
| 74 | electron transport chain (GO:0022900) | 2.84172861 |
| 75 | protein neddylation (GO:0045116) | 2.83101468 |
| 76 | cellular ketone body metabolic process (GO:0046950) | 2.80944192 |
| 77 | reciprocal DNA recombination (GO:0035825) | 2.80796055 |
| 78 | reciprocal meiotic recombination (GO:0007131) | 2.80796055 |
| 79 | recombinational repair (GO:0000725) | 2.80483541 |
| 80 | * translation (GO:0006412) | 2.80007184 |
| 81 | double-strand break repair via homologous recombination (GO:0000724) | 2.75814802 |
| 82 | pseudouridine synthesis (GO:0001522) | 2.71718703 |
| 83 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.71453869 |
| 84 | DNA replication-independent nucleosome organization (GO:0034724) | 2.70777779 |
| 85 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.70777779 |
| 86 | negative regulation of DNA recombination (GO:0045910) | 2.70344076 |
| 87 | cellular protein complex disassembly (GO:0043624) | 2.69926215 |
| 88 | axoneme assembly (GO:0035082) | 2.68415492 |
| 89 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.66399233 |
| 90 | protein polyglutamylation (GO:0018095) | 2.65166012 |
| 91 | 2-deoxyribonucleotide metabolic process (GO:0009394) | 2.63868893 |
| 92 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.62027846 |
| 93 | nucleotide salvage (GO:0043173) | 2.61668929 |
| 94 | regulation of oxidative phosphorylation (GO:0002082) | 2.61429273 |
| 95 | peptidyl-histidine modification (GO:0018202) | 2.61303147 |
| 96 | regulation of cellular respiration (GO:0043457) | 2.61116922 |
| 97 | * rRNA processing (GO:0006364) | 2.60362522 |
| 98 | deoxyribose phosphate metabolic process (GO:0019692) | 2.60225117 |
| 99 | dopamine transport (GO:0015872) | 2.59089020 |
| 100 | UMP biosynthetic process (GO:0006222) | 2.59006842 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.30664605 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.10807369 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.01495425 |
| 4 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.51267324 |
| 5 | * ZNF274_21170338_ChIP-Seq_K562_Hela | 3.21009788 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.19688268 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.05946212 |
| 8 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.96721310 |
| 9 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.90334651 |
| 10 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.63280400 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.48450101 |
| 12 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.39456531 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.37447035 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.29171856 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.25173841 |
| 16 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.10334300 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 2.09823729 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.09422929 |
| 19 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.99252482 |
| 20 | FUS_26573619_Chip-Seq_HEK293_Human | 1.98471032 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.98139493 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.94798113 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.90429767 |
| 24 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.88514964 |
| 25 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.83375690 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.79189202 |
| 27 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.75575785 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.75238567 |
| 29 | * VDR_22108803_ChIP-Seq_LS180_Human | 1.71258565 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.67052932 |
| 31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.63151372 |
| 32 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.60670005 |
| 33 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.60077829 |
| 34 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.59977115 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.59275613 |
| 36 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.55182267 |
| 37 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.53034863 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.49665689 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.49004182 |
| 40 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.40936529 |
| 41 | P300_19829295_ChIP-Seq_ESCs_Human | 1.38879331 |
| 42 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.34699179 |
| 43 | * CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.34132454 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.33698542 |
| 45 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.30371675 |
| 46 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.27746117 |
| 47 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25759319 |
| 48 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25759319 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.23751855 |
| 50 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.23664677 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.23467248 |
| 52 | * GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.23411581 |
| 53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.23353536 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.22772184 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.22772184 |
| 56 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.21605613 |
| 57 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.21361242 |
| 58 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.21128722 |
| 59 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.19507180 |
| 60 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.18500205 |
| 61 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.18247363 |
| 62 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.13928302 |
| 63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.13616465 |
| 64 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.13616465 |
| 65 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.13423452 |
| 66 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.13074372 |
| 67 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.09215237 |
| 68 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02557709 |
| 69 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.01539959 |
| 70 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.01359340 |
| 71 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.00619648 |
| 72 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.00340046 |
| 73 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.00087880 |
| 74 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99142510 |
| 75 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.98609431 |
| 76 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.98258546 |
| 77 | * ER_23166858_ChIP-Seq_MCF-7_Human | 0.96921805 |
| 78 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.96441367 |
| 79 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.96238787 |
| 80 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.95675895 |
| 81 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.94189020 |
| 82 | * TCF4_22108803_ChIP-Seq_LS180_Human | 0.92196726 |
| 83 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.90697241 |
| 84 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.89337438 |
| 85 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.89198844 |
| 86 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.88878092 |
| 87 | NCOR_22424771_ChIP-Seq_293T_Human | 0.87847296 |
| 88 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.87380181 |
| 89 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.87236407 |
| 90 | * CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.86955177 |
| 91 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.86257278 |
| 92 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.85781823 |
| 93 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.85122830 |
| 94 | * KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.84966567 |
| 95 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.84920180 |
| 96 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.84750944 |
| 97 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.84558630 |
| 98 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.83719976 |
| 99 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.83275234 |
| 100 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.82947086 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 4.55374758 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.70246551 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.41367524 |
| 4 | MP0005645_abnormal_hypothalamus_physiol | 2.88300661 |
| 5 | MP0002234_abnormal_pharynx_morphology | 2.67044758 |
| 6 | MP0008058_abnormal_DNA_repair | 2.55219730 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.28921108 |
| 8 | MP0001529_abnormal_vocalization | 2.28815713 |
| 9 | MP0003718_maternal_effect | 2.25774283 |
| 10 | MP0004043_abnormal_pH_regulation | 2.13276291 |
| 11 | MP0000566_synostosis | 2.10425525 |
| 12 | MP0008872_abnormal_physiological_respon | 2.08183850 |
| 13 | MP0003123_paternal_imprinting | 2.04838204 |
| 14 | MP0003693_abnormal_embryo_hatching | 1.96644684 |
| 15 | MP0008995_early_reproductive_senescence | 1.95415779 |
| 16 | MP0003786_premature_aging | 1.88031692 |
| 17 | MP0010094_abnormal_chromosome_stability | 1.87352439 |
| 18 | MP0002938_white_spotting | 1.83417457 |
| 19 | MP0008789_abnormal_olfactory_epithelium | 1.80497546 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.76577052 |
| 21 | MP0001764_abnormal_homeostasis | 1.71715600 |
| 22 | MP0003890_abnormal_embryonic-extraembry | 1.65841775 |
| 23 | MP0005551_abnormal_eye_electrophysiolog | 1.60227073 |
| 24 | MP0003283_abnormal_digestive_organ | 1.59053817 |
| 25 | MP0003937_abnormal_limbs/digits/tail_de | 1.56815464 |
| 26 | MP0005646_abnormal_pituitary_gland | 1.52111509 |
| 27 | MP0001661_extended_life_span | 1.49234437 |
| 28 | MP0005394_taste/olfaction_phenotype | 1.45887611 |
| 29 | MP0005499_abnormal_olfactory_system | 1.45887611 |
| 30 | MP0003567_abnormal_fetal_cardiomyocyte | 1.45411489 |
| 31 | MP0004142_abnormal_muscle_tone | 1.45036667 |
| 32 | MP0002102_abnormal_ear_morphology | 1.42356761 |
| 33 | MP0003121_genomic_imprinting | 1.41954803 |
| 34 | MP0005253_abnormal_eye_physiology | 1.39885476 |
| 35 | MP0006036_abnormal_mitochondrial_physio | 1.39358660 |
| 36 | MP0002132_abnormal_respiratory_system | 1.37038490 |
| 37 | MP0005389_reproductive_system_phenotype | 1.36032169 |
| 38 | MP0003186_abnormal_redox_activity | 1.34874223 |
| 39 | MP0005084_abnormal_gallbladder_morpholo | 1.34627437 |
| 40 | MP0003787_abnormal_imprinting | 1.31775182 |
| 41 | MP0001919_abnormal_reproductive_system | 1.29540865 |
| 42 | MP0006035_abnormal_mitochondrial_morpho | 1.29078119 |
| 43 | MP0001293_anophthalmia | 1.28492074 |
| 44 | MP0003315_abnormal_perineum_morphology | 1.28360753 |
| 45 | MP0004957_abnormal_blastocyst_morpholog | 1.27374347 |
| 46 | MP0004885_abnormal_endolymph | 1.27270697 |
| 47 | MP0002638_abnormal_pupillary_reflex | 1.27073346 |
| 48 | MP0004147_increased_porphyrin_level | 1.25957223 |
| 49 | MP0002233_abnormal_nose_morphology | 1.25141421 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.24869638 |
| 51 | MP0003195_calcinosis | 1.22322249 |
| 52 | MP0002876_abnormal_thyroid_physiology | 1.19679592 |
| 53 | MP0002210_abnormal_sex_determination | 1.16076145 |
| 54 | MP0000631_abnormal_neuroendocrine_gland | 1.15715384 |
| 55 | MP0001905_abnormal_dopamine_level | 1.15257682 |
| 56 | MP0002163_abnormal_gland_morphology | 1.14979590 |
| 57 | MP0002277_abnormal_respiratory_mucosa | 1.14211912 |
| 58 | MP0003119_abnormal_digestive_system | 1.11320912 |
| 59 | MP0002095_abnormal_skin_pigmentation | 1.11274248 |
| 60 | MP0001119_abnormal_female_reproductive | 1.07581772 |
| 61 | MP0004133_heterotaxia | 1.07501680 |
| 62 | MP0002160_abnormal_reproductive_system | 1.06370820 |
| 63 | MP0001929_abnormal_gametogenesis | 1.01173380 |
| 64 | MP0000653_abnormal_sex_gland | 1.00076799 |
| 65 | MP0004742_abnormal_vestibular_system | 0.99432742 |
| 66 | MP0001873_stomach_inflammation | 0.99009035 |
| 67 | MP0000372_irregular_coat_pigmentation | 0.98396404 |
| 68 | MP0005075_abnormal_melanosome_morpholog | 0.95085518 |
| 69 | MP0000049_abnormal_middle_ear | 0.94413078 |
| 70 | MP0001145_abnormal_male_reproductive | 0.90292177 |
| 71 | MP0000516_abnormal_urinary_system | 0.90212259 |
| 72 | MP0005367_renal/urinary_system_phenotyp | 0.90212259 |
| 73 | MP0005671_abnormal_response_to | 0.89364948 |
| 74 | MP0002736_abnormal_nociception_after | 0.86830915 |
| 75 | MP0003698_abnormal_male_reproductive | 0.81183212 |
| 76 | MP0010368_abnormal_lymphatic_system | 0.80561315 |
| 77 | MP0003122_maternal_imprinting | 0.80220807 |
| 78 | MP0001485_abnormal_pinna_reflex | 0.79751142 |
| 79 | MP0004145_abnormal_muscle_electrophysio | 0.79508983 |
| 80 | MP0005174_abnormal_tail_pigmentation | 0.77247501 |
| 81 | MP0003938_abnormal_ear_development | 0.76768811 |
| 82 | MP0009745_abnormal_behavioral_response | 0.75080449 |
| 83 | MP0009697_abnormal_copulation | 0.73660684 |
| 84 | MP0008007_abnormal_cellular_replicative | 0.73280898 |
| 85 | MP0002751_abnormal_autonomic_nervous | 0.72861892 |
| 86 | MP0002127_abnormal_cardiovascular_syste | 0.72807142 |
| 87 | MP0008875_abnormal_xenobiotic_pharmacok | 0.72421651 |
| 88 | MP0002109_abnormal_limb_morphology | 0.72001293 |
| 89 | MP0002557_abnormal_social/conspecific_i | 0.70837799 |
| 90 | MP0009053_abnormal_anal_canal | 0.69546561 |
| 91 | MP0005220_abnormal_exocrine_pancreas | 0.69220932 |
| 92 | MP0005636_abnormal_mineral_homeostasis | 0.67366702 |
| 93 | MP0008932_abnormal_embryonic_tissue | 0.66910942 |
| 94 | MP0005195_abnormal_posterior_eye | 0.64477766 |
| 95 | MP0003111_abnormal_nucleus_morphology | 0.64153894 |
| 96 | MP0010307_abnormal_tumor_latency | 0.63471575 |
| 97 | MP0005167_abnormal_blood-brain_barrier | 0.63354562 |
| 98 | MP0003936_abnormal_reproductive_system | 0.62866282 |
| 99 | MP0002396_abnormal_hematopoietic_system | 0.62595470 |
| 100 | MP0001188_hyperpigmentation | 0.62173638 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.60357041 |
| 2 | Acute encephalopathy (HP:0006846) | 4.09505189 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.92430541 |
| 4 | Progressive macrocephaly (HP:0004481) | 3.81544684 |
| 5 | Mitochondrial inheritance (HP:0001427) | 3.63419029 |
| 6 | Increased CSF lactate (HP:0002490) | 3.46378897 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.40257917 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.37289748 |
| 9 | Pancreatic cysts (HP:0001737) | 3.33803287 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 3.28124985 |
| 11 | Hepatic necrosis (HP:0002605) | 3.27773827 |
| 12 | Pancreatic fibrosis (HP:0100732) | 3.20753647 |
| 13 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.11097131 |
| 14 | Asplenia (HP:0001746) | 2.97755764 |
| 15 | Reticulocytopenia (HP:0001896) | 2.96913098 |
| 16 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.92657040 |
| 17 | Cerebral edema (HP:0002181) | 2.90464293 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 2.89523335 |
| 19 | Optic disc pallor (HP:0000543) | 2.72394095 |
| 20 | Autoimmune thrombocytopenia (HP:0001973) | 2.71770095 |
| 21 | Abnormality of midbrain morphology (HP:0002418) | 2.68049995 |
| 22 | Molar tooth sign on MRI (HP:0002419) | 2.68049995 |
| 23 | Ectopic kidney (HP:0000086) | 2.67568385 |
| 24 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.63862161 |
| 25 | Abnormality of alanine metabolism (HP:0010916) | 2.63862161 |
| 26 | Hyperalaninemia (HP:0003348) | 2.63862161 |
| 27 | Chromsome breakage (HP:0040012) | 2.63026009 |
| 28 | B lymphocytopenia (HP:0010976) | 2.62968653 |
| 29 | Methylmalonic acidemia (HP:0002912) | 2.62074284 |
| 30 | Supernumerary spleens (HP:0009799) | 2.60912503 |
| 31 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.51280229 |
| 32 | Abnormality of B cell number (HP:0010975) | 2.50694792 |
| 33 | True hermaphroditism (HP:0010459) | 2.50003414 |
| 34 | Absent thumb (HP:0009777) | 2.48562522 |
| 35 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.46992640 |
| 36 | Increased serum lactate (HP:0002151) | 2.43344918 |
| 37 | Abolished electroretinogram (ERG) (HP:0000550) | 2.42430091 |
| 38 | Colon cancer (HP:0003003) | 2.41983766 |
| 39 | Abnormality of the renal cortex (HP:0011035) | 2.41792565 |
| 40 | Congenital stationary night blindness (HP:0007642) | 2.40764399 |
| 41 | Hyperglycinemia (HP:0002154) | 2.40244581 |
| 42 | Meckel diverticulum (HP:0002245) | 2.36614548 |
| 43 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.35395999 |
| 44 | Abnormality of chromosome stability (HP:0003220) | 2.33598439 |
| 45 | Abnormality of the ileum (HP:0001549) | 2.31249375 |
| 46 | 3-Methylglutaconic aciduria (HP:0003535) | 2.27904498 |
| 47 | Anal stenosis (HP:0002025) | 2.27303665 |
| 48 | Bile duct proliferation (HP:0001408) | 2.25715170 |
| 49 | Abnormal biliary tract physiology (HP:0012439) | 2.25715170 |
| 50 | Respiratory difficulties (HP:0002880) | 2.22576199 |
| 51 | Lip pit (HP:0100267) | 2.19932830 |
| 52 | Chronic bronchitis (HP:0004469) | 2.18994945 |
| 53 | Abnormal drinking behavior (HP:0030082) | 2.18433224 |
| 54 | Polydipsia (HP:0001959) | 2.18433224 |
| 55 | Constricted visual fields (HP:0001133) | 2.17386533 |
| 56 | Methylmalonic aciduria (HP:0012120) | 2.15690173 |
| 57 | Exertional dyspnea (HP:0002875) | 2.15420230 |
| 58 | Abnormality of urine glucose concentration (HP:0011016) | 2.10838751 |
| 59 | Glycosuria (HP:0003076) | 2.10838751 |
| 60 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.10304136 |
| 61 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.07379718 |
| 62 | Severe combined immunodeficiency (HP:0004430) | 2.06935168 |
| 63 | Intestinal fistula (HP:0100819) | 2.06742347 |
| 64 | Nephronophthisis (HP:0000090) | 2.06657933 |
| 65 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.04437451 |
| 66 | Attenuation of retinal blood vessels (HP:0007843) | 2.04005334 |
| 67 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.02697878 |
| 68 | Pendular nystagmus (HP:0012043) | 2.02597293 |
| 69 | Thyroiditis (HP:0100646) | 1.99901946 |
| 70 | Lethargy (HP:0001254) | 1.99613230 |
| 71 | Triphalangeal thumb (HP:0001199) | 1.99104345 |
| 72 | Increased intramyocellular lipid droplets (HP:0012240) | 1.98690197 |
| 73 | Abnormality of DNA repair (HP:0003254) | 1.97476635 |
| 74 | Lactic acidosis (HP:0003128) | 1.95285116 |
| 75 | Abnormality of the preputium (HP:0100587) | 1.93291515 |
| 76 | Chronic hepatic failure (HP:0100626) | 1.92604408 |
| 77 | Abnormality of the renal medulla (HP:0100957) | 1.91860101 |
| 78 | Abnormality of macular pigmentation (HP:0008002) | 1.91193775 |
| 79 | Rhinitis (HP:0012384) | 1.89933330 |
| 80 | Anencephaly (HP:0002323) | 1.89845616 |
| 81 | Abnormality of serum amino acid levels (HP:0003112) | 1.88959273 |
| 82 | Renal cortical cysts (HP:0000803) | 1.87545828 |
| 83 | Decreased central vision (HP:0007663) | 1.86692164 |
| 84 | Aplastic anemia (HP:0001915) | 1.86283572 |
| 85 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.85941630 |
| 86 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.85941630 |
| 87 | Macrocytic anemia (HP:0001972) | 1.85237005 |
| 88 | Postaxial foot polydactyly (HP:0001830) | 1.84297230 |
| 89 | Leukodystrophy (HP:0002415) | 1.83189934 |
| 90 | Medial flaring of the eyebrow (HP:0010747) | 1.81079165 |
| 91 | Cystic liver disease (HP:0006706) | 1.80534272 |
| 92 | Abnormality of renal resorption (HP:0011038) | 1.79132408 |
| 93 | Abnormality of the labia minora (HP:0012880) | 1.77310551 |
| 94 | Tubular atrophy (HP:0000092) | 1.77267450 |
| 95 | Median cleft lip (HP:0000161) | 1.76734109 |
| 96 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.75661897 |
| 97 | Generalized aminoaciduria (HP:0002909) | 1.74843116 |
| 98 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.74059699 |
| 99 | CNS demyelination (HP:0007305) | 1.72503751 |
| 100 | Respiratory failure (HP:0002878) | 1.71523859 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 3.45226459 |
| 2 | WNK4 | 3.15950620 |
| 3 | PBK | 3.05504621 |
| 4 | ZAK | 2.97220463 |
| 5 | BMPR1B | 2.54236066 |
| 6 | NUAK1 | 2.54127160 |
| 7 | STK39 | 2.49925715 |
| 8 | STK24 | 2.44736369 |
| 9 | TNIK | 2.43183790 |
| 10 | ACVR1B | 2.20839498 |
| 11 | PINK1 | 2.11068898 |
| 12 | WNK3 | 1.92528639 |
| 13 | MAP4K2 | 1.89653640 |
| 14 | STK16 | 1.82646664 |
| 15 | BRSK2 | 1.81516821 |
| 16 | CDC7 | 1.75188989 |
| 17 | TAF1 | 1.69606747 |
| 18 | CCNB1 | 1.66586832 |
| 19 | DYRK2 | 1.65209981 |
| 20 | VRK1 | 1.63310439 |
| 21 | GRK1 | 1.56149875 |
| 22 | PLK4 | 1.55851529 |
| 23 | CDK19 | 1.53539706 |
| 24 | MKNK2 | 1.53029111 |
| 25 | PLK3 | 1.52797045 |
| 26 | BUB1 | 1.35805946 |
| 27 | TTK | 1.35161760 |
| 28 | FRK | 1.29167193 |
| 29 | SRPK1 | 1.27894470 |
| 30 | BCKDK | 1.26438620 |
| 31 | TXK | 1.24827622 |
| 32 | CHEK2 | 1.23646532 |
| 33 | MST4 | 1.20259114 |
| 34 | WEE1 | 1.19805097 |
| 35 | PRKCQ | 1.14793701 |
| 36 | ADRBK2 | 1.09280570 |
| 37 | MKNK1 | 1.07492893 |
| 38 | PRKCH | 1.06243424 |
| 39 | EIF2AK3 | 1.04479274 |
| 40 | ILK | 1.02489466 |
| 41 | KDR | 0.97483790 |
| 42 | MAPK13 | 0.97311903 |
| 43 | TRIM28 | 0.96276119 |
| 44 | TSSK6 | 0.94158866 |
| 45 | PDK2 | 0.92313896 |
| 46 | CSNK1G1 | 0.92261010 |
| 47 | PLK2 | 0.92183405 |
| 48 | PASK | 0.89991819 |
| 49 | ADRBK1 | 0.89481949 |
| 50 | NME1 | 0.86649638 |
| 51 | PLK1 | 0.86342699 |
| 52 | RPS6KB2 | 0.83416881 |
| 53 | MINK1 | 0.82746726 |
| 54 | NLK | 0.82328392 |
| 55 | DAPK1 | 0.82151634 |
| 56 | MAP4K1 | 0.75940101 |
| 57 | MAPKAPK5 | 0.75691434 |
| 58 | BRSK1 | 0.75205754 |
| 59 | ATR | 0.73650402 |
| 60 | PNCK | 0.73320431 |
| 61 | CDK9 | 0.72274748 |
| 62 | CAMKK2 | 0.70705576 |
| 63 | TGFBR1 | 0.69007523 |
| 64 | EIF2AK2 | 0.68464054 |
| 65 | CAMK1 | 0.68153920 |
| 66 | WNK1 | 0.65953231 |
| 67 | CSNK1G3 | 0.65735636 |
| 68 | CSNK1G2 | 0.64269103 |
| 69 | INSRR | 0.62911437 |
| 70 | STK4 | 0.61787120 |
| 71 | NEK2 | 0.56934377 |
| 72 | JAK3 | 0.54383625 |
| 73 | MAP3K2 | 0.54255482 |
| 74 | DAPK2 | 0.52555968 |
| 75 | OXSR1 | 0.51908226 |
| 76 | TNK2 | 0.51872272 |
| 77 | ERBB3 | 0.51729287 |
| 78 | TLK1 | 0.50963723 |
| 79 | PRKCG | 0.50955592 |
| 80 | DYRK3 | 0.49815660 |
| 81 | EIF2AK1 | 0.49695485 |
| 82 | ATM | 0.46756845 |
| 83 | TEC | 0.44059995 |
| 84 | PKN1 | 0.43281934 |
| 85 | CSNK2A2 | 0.42489732 |
| 86 | NTRK2 | 0.42080262 |
| 87 | CDK3 | 0.41420753 |
| 88 | TIE1 | 0.41369784 |
| 89 | CSNK2A1 | 0.40629995 |
| 90 | TAOK3 | 0.39850179 |
| 91 | PRKCE | 0.39008403 |
| 92 | ERBB4 | 0.38052784 |
| 93 | PRKCI | 0.37403238 |
| 94 | RPS6KA6 | 0.37270319 |
| 95 | GRK5 | 0.37093217 |
| 96 | PRKCD | 0.36593154 |
| 97 | FLT3 | 0.35795161 |
| 98 | TESK2 | 0.35575368 |
| 99 | CAMK4 | 0.34281910 |
| 100 | AURKB | 0.33818676 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.71967773 |
| 2 | RNA polymerase_Homo sapiens_hsa03020 | 3.65478051 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.26685199 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.82508445 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.68245239 |
| 6 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.57370081 |
| 7 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.43591716 |
| 8 | Homologous recombination_Homo sapiens_hsa03440 | 2.33782317 |
| 9 | Protein export_Homo sapiens_hsa03060 | 2.13752297 |
| 10 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.09218947 |
| 11 | Mismatch repair_Homo sapiens_hsa03430 | 2.07158340 |
| 12 | DNA replication_Homo sapiens_hsa03030 | 2.05373197 |
| 13 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.04081177 |
| 14 | Basal transcription factors_Homo sapiens_hsa03022 | 1.99283461 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.93877317 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.88669699 |
| 17 | Base excision repair_Homo sapiens_hsa03410 | 1.86976667 |
| 18 | Phototransduction_Homo sapiens_hsa04744 | 1.84984256 |
| 19 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.82150419 |
| 20 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.71097823 |
| 21 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.69382525 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.68409266 |
| 23 | RNA transport_Homo sapiens_hsa03013 | 1.57626261 |
| 24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.55933887 |
| 25 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.52900477 |
| 26 | Alzheimers disease_Homo sapiens_hsa05010 | 1.50643010 |
| 27 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.50316958 |
| 28 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.48151269 |
| 29 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.45127694 |
| 30 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.44281730 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.40008153 |
| 32 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.39420175 |
| 33 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.33585759 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.31870683 |
| 35 | Purine metabolism_Homo sapiens_hsa00230 | 1.31712846 |
| 36 | Peroxisome_Homo sapiens_hsa04146 | 1.21638505 |
| 37 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.20595341 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.20170848 |
| 39 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.15299599 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.13462194 |
| 41 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.08639518 |
| 42 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.08203926 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 1.07212254 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.03796823 |
| 45 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.03564379 |
| 46 | Spliceosome_Homo sapiens_hsa03040 | 1.02100673 |
| 47 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.00346440 |
| 48 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.99670697 |
| 49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.99130622 |
| 50 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.96786695 |
| 51 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.95194935 |
| 52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85295826 |
| 53 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.84047501 |
| 54 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.83449166 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.79737607 |
| 56 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.77702427 |
| 57 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.77447754 |
| 58 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.75692855 |
| 59 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.75073066 |
| 60 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.74763148 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.73681870 |
| 62 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.72667882 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72105996 |
| 64 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.68880250 |
| 65 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67906969 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.67853771 |
| 67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.65196331 |
| 68 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64354003 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.62888151 |
| 70 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.61957911 |
| 71 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.61601852 |
| 72 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.60639383 |
| 73 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.56263629 |
| 74 | Allograft rejection_Homo sapiens_hsa05330 | 0.51803787 |
| 75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.51382855 |
| 76 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.50722015 |
| 77 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.50701063 |
| 78 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.45851191 |
| 79 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.45425460 |
| 80 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45322640 |
| 81 | Cell cycle_Homo sapiens_hsa04110 | 0.44182498 |
| 82 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.43872505 |
| 83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43584952 |
| 84 | Taste transduction_Homo sapiens_hsa04742 | 0.42604035 |
| 85 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.39855745 |
| 86 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.37800476 |
| 87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.36717353 |
| 88 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.36079223 |
| 89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.36038186 |
| 90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.34118213 |
| 91 | Asthma_Homo sapiens_hsa05310 | 0.33627766 |
| 92 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.32521271 |
| 93 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.31281792 |
| 94 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.30731811 |
| 95 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.28919271 |
| 96 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.26294931 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.23093628 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.21213888 |
| 99 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21207368 |
| 100 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.20871123 |

