

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.76048337 |
| 2 | proteasome assembly (GO:0043248) | 4.97406690 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.68955577 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.68171550 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.68171550 |
| 6 | ubiquinone biosynthetic process (GO:0006744) | 4.58744379 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 4.55404301 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.45541934 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 4.42724888 |
| 10 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.33860910 |
| 11 | peptidyl-histidine modification (GO:0018202) | 4.31373214 |
| 12 | ubiquinone metabolic process (GO:0006743) | 4.02781018 |
| 13 | protein complex biogenesis (GO:0070271) | 4.01697468 |
| 14 | cytidine deamination (GO:0009972) | 3.92866439 |
| 15 | cytidine metabolic process (GO:0046087) | 3.92866439 |
| 16 | cytidine catabolic process (GO:0006216) | 3.92866439 |
| 17 | regulation of mitochondrial translation (GO:0070129) | 3.89122901 |
| 18 | respiratory electron transport chain (GO:0022904) | 3.86499323 |
| 19 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.85155077 |
| 20 | electron transport chain (GO:0022900) | 3.84466030 |
| 21 | quinone biosynthetic process (GO:1901663) | 3.81284566 |
| 22 | pseudouridine synthesis (GO:0001522) | 3.77444607 |
| 23 | termination of RNA polymerase III transcription (GO:0006386) | 3.76816048 |
| 24 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.76816048 |
| 25 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.70356768 |
| 26 | maturation of SSU-rRNA (GO:0030490) | 3.70027351 |
| 27 | negative regulation of telomere maintenance (GO:0032205) | 3.66705963 |
| 28 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.64357132 |
| 29 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.60238833 |
| 30 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.58537925 |
| 31 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.58537925 |
| 32 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.55760712 |
| 33 | NADH dehydrogenase complex assembly (GO:0010257) | 3.55760712 |
| 34 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.55760712 |
| 35 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.52194572 |
| 36 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.48029262 |
| 37 | DNA damage response, detection of DNA damage (GO:0042769) | 3.30843844 |
| 38 | response to interferon-beta (GO:0035456) | 3.28254432 |
| 39 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.24815588 |
| 40 | respiratory chain complex IV assembly (GO:0008535) | 3.23932929 |
| 41 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.22722208 |
| 42 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.21570003 |
| 43 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.21262150 |
| 44 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.20226910 |
| 45 | negative regulation of ligase activity (GO:0051352) | 3.17364364 |
| 46 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.17364364 |
| 47 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.10918610 |
| 48 | cytochrome complex assembly (GO:0017004) | 3.10664101 |
| 49 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.08826134 |
| 50 | spliceosomal snRNP assembly (GO:0000387) | 3.07023308 |
| 51 | translational termination (GO:0006415) | 3.04703439 |
| 52 | metallo-sulfur cluster assembly (GO:0031163) | 3.04108048 |
| 53 | iron-sulfur cluster assembly (GO:0016226) | 3.04108048 |
| 54 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.03903125 |
| 55 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.03903125 |
| 56 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.03903125 |
| 57 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.00452811 |
| 58 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.00452811 |
| 59 | rRNA processing (GO:0006364) | 3.00149647 |
| 60 | translation (GO:0006412) | 2.99006832 |
| 61 | viral transcription (GO:0019083) | 2.98450802 |
| 62 | histone mRNA metabolic process (GO:0008334) | 2.98271162 |
| 63 | rRNA metabolic process (GO:0016072) | 2.97660453 |
| 64 | indole-containing compound catabolic process (GO:0042436) | 2.97306009 |
| 65 | indolalkylamine catabolic process (GO:0046218) | 2.97306009 |
| 66 | tryptophan catabolic process (GO:0006569) | 2.97306009 |
| 67 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.96826666 |
| 68 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.96826666 |
| 69 | ribosomal small subunit biogenesis (GO:0042274) | 2.96582459 |
| 70 | response to pheromone (GO:0019236) | 2.96523019 |
| 71 | protein neddylation (GO:0045116) | 2.92896440 |
| 72 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.92243687 |
| 73 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.92046388 |
| 74 | dopamine transport (GO:0015872) | 2.90243657 |
| 75 | DNA double-strand break processing (GO:0000729) | 2.90072882 |
| 76 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.87275520 |
| 77 | cotranslational protein targeting to membrane (GO:0006613) | 2.86161840 |
| 78 | rRNA modification (GO:0000154) | 2.84587142 |
| 79 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.84419262 |
| 80 | protein targeting to ER (GO:0045047) | 2.81778404 |
| 81 | DNA replication checkpoint (GO:0000076) | 2.77285432 |
| 82 | base-excision repair, AP site formation (GO:0006285) | 2.76972338 |
| 83 | cellular component biogenesis (GO:0044085) | 2.75342770 |
| 84 | tRNA processing (GO:0008033) | 2.75275548 |
| 85 | chromatin remodeling at centromere (GO:0031055) | 2.73505083 |
| 86 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.70339297 |
| 87 | cellular response to interferon-beta (GO:0035458) | 2.70071211 |
| 88 | protein localization to endoplasmic reticulum (GO:0070972) | 2.69941963 |
| 89 | GTP biosynthetic process (GO:0006183) | 2.69238798 |
| 90 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.68518325 |
| 91 | translational elongation (GO:0006414) | 2.67907294 |
| 92 | kynurenine metabolic process (GO:0070189) | 2.65016584 |
| 93 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.64986475 |
| 94 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.61079998 |
| 95 | isotype switching (GO:0045190) | 2.61079998 |
| 96 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.61079998 |
| 97 | CENP-A containing nucleosome assembly (GO:0034080) | 2.60503875 |
| 98 | purine nucleotide salvage (GO:0032261) | 2.59088546 |
| 99 | ncRNA processing (GO:0034470) | 2.58775070 |
| 100 | ncRNA metabolic process (GO:0034660) | 2.58302910 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.80446098 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.76666845 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21958974 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.02689307 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.32720586 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.13348634 |
| 7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.11382827 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.96348571 |
| 9 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.74656149 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.73815323 |
| 11 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.69566068 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.64711454 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.62680219 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.61647966 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.47650943 |
| 16 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.40369109 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.32532687 |
| 18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.25684612 |
| 19 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.23079440 |
| 20 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.18749770 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.18604144 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.14235727 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.94863451 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.90482453 |
| 25 | VDR_22108803_ChIP-Seq_LS180_Human | 1.86309823 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.85270380 |
| 27 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.74409142 |
| 28 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.65598122 |
| 29 | FUS_26573619_Chip-Seq_HEK293_Human | 1.62105891 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.62068725 |
| 31 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.59920365 |
| 32 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.57994872 |
| 33 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.53369592 |
| 34 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.50038195 |
| 35 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.49118269 |
| 36 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.45088793 |
| 37 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.43008722 |
| 38 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.42577436 |
| 39 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.41996033 |
| 40 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.40225611 |
| 41 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.36213946 |
| 42 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.36213946 |
| 43 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.35462007 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.33396574 |
| 45 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.33034255 |
| 46 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.29881263 |
| 47 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.29692096 |
| 48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.29606800 |
| 49 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.29530435 |
| 50 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.28621854 |
| 51 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.23362457 |
| 52 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.22098055 |
| 53 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.21770215 |
| 54 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.20536492 |
| 55 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.20440373 |
| 56 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20419708 |
| 57 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.19297984 |
| 58 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.18604553 |
| 59 | P300_19829295_ChIP-Seq_ESCs_Human | 1.17900268 |
| 60 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14525537 |
| 61 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.14463554 |
| 62 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.09557104 |
| 63 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.09463711 |
| 64 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.09066695 |
| 65 | AR_20517297_ChIP-Seq_VCAP_Human | 1.08657769 |
| 66 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08423880 |
| 67 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.08308918 |
| 68 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.08215764 |
| 69 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.07453447 |
| 70 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.06970708 |
| 71 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.05706148 |
| 72 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05641184 |
| 73 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 1.04707613 |
| 74 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.04512487 |
| 75 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04468044 |
| 76 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.03358800 |
| 77 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03030961 |
| 78 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.02320987 |
| 79 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.01815794 |
| 80 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.01773126 |
| 81 | NCOR_22424771_ChIP-Seq_293T_Human | 1.01195099 |
| 82 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99322526 |
| 83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99322526 |
| 84 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99273462 |
| 85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.99045820 |
| 86 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.98993271 |
| 87 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.98019683 |
| 88 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.95998999 |
| 89 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.95998999 |
| 90 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95701742 |
| 91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.95242519 |
| 92 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.95237626 |
| 93 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.94951767 |
| 94 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.94283348 |
| 95 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.92438042 |
| 96 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.92071387 |
| 97 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 0.91628609 |
| 98 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.91048910 |
| 99 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.89360481 |
| 100 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88817072 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005084_abnormal_gallbladder_morpholo | 5.13384094 |
| 2 | MP0002138_abnormal_hepatobiliary_system | 4.54688427 |
| 3 | MP0005360_urolithiasis | 3.11181305 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.05766951 |
| 5 | MP0008058_abnormal_DNA_repair | 2.86667355 |
| 6 | MP0003786_premature_aging | 2.39815360 |
| 7 | MP0009379_abnormal_foot_pigmentation | 2.26173648 |
| 8 | MP0001873_stomach_inflammation | 2.21808659 |
| 9 | MP0005671_abnormal_response_to | 2.16416021 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.12646137 |
| 11 | MP0001968_abnormal_touch/_nociception | 2.01546060 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 1.90780036 |
| 13 | MP0008872_abnormal_physiological_respon | 1.90185840 |
| 14 | MP0002277_abnormal_respiratory_mucosa | 1.89326069 |
| 15 | MP0003252_abnormal_bile_duct | 1.80527146 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 1.75072041 |
| 17 | MP0000372_irregular_coat_pigmentation | 1.74715095 |
| 18 | MP0004957_abnormal_blastocyst_morpholog | 1.74144365 |
| 19 | MP0002102_abnormal_ear_morphology | 1.73970821 |
| 20 | MP0002736_abnormal_nociception_after | 1.73089650 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.67838039 |
| 22 | MP0001348_abnormal_lacrimal_gland | 1.65329645 |
| 23 | MP0001188_hyperpigmentation | 1.62210085 |
| 24 | MP0001984_abnormal_olfaction | 1.47947428 |
| 25 | MP0003718_maternal_effect | 1.44750592 |
| 26 | MP0000685_abnormal_immune_system | 1.43270848 |
| 27 | MP0002160_abnormal_reproductive_system | 1.41077867 |
| 28 | MP0008995_early_reproductive_senescence | 1.38902067 |
| 29 | MP0004142_abnormal_muscle_tone | 1.38496978 |
| 30 | MP0000538_abnormal_urinary_bladder | 1.33350381 |
| 31 | MP0008057_abnormal_DNA_replication | 1.30454811 |
| 32 | MP0003567_abnormal_fetal_cardiomyocyte | 1.29812888 |
| 33 | MP0005389_reproductive_system_phenotype | 1.29722753 |
| 34 | MP0006276_abnormal_autonomic_nervous | 1.28667148 |
| 35 | MP0005646_abnormal_pituitary_gland | 1.26745562 |
| 36 | MP0001835_abnormal_antigen_presentation | 1.26229105 |
| 37 | MP0010094_abnormal_chromosome_stability | 1.26203622 |
| 38 | MP0010368_abnormal_lymphatic_system | 1.26185876 |
| 39 | MP0004147_increased_porphyrin_level | 1.24146261 |
| 40 | MP0003646_muscle_fatigue | 1.23450400 |
| 41 | MP0008007_abnormal_cellular_replicative | 1.19600604 |
| 42 | MP0009250_abnormal_appendicular_skeleto | 1.14765588 |
| 43 | MP0002163_abnormal_gland_morphology | 1.14046000 |
| 44 | MP0005551_abnormal_eye_electrophysiolog | 1.11747610 |
| 45 | MP0001919_abnormal_reproductive_system | 1.11197338 |
| 46 | MP0010386_abnormal_urinary_bladder | 1.09802215 |
| 47 | MP0001485_abnormal_pinna_reflex | 1.08110834 |
| 48 | MP0000647_abnormal_sebaceous_gland | 1.08001519 |
| 49 | MP0006035_abnormal_mitochondrial_morpho | 1.04319157 |
| 50 | MP0009697_abnormal_copulation | 1.04031884 |
| 51 | MP0003763_abnormal_thymus_physiology | 1.04017367 |
| 52 | MP0002876_abnormal_thyroid_physiology | 1.02009855 |
| 53 | MP0005377_hearing/vestibular/ear_phenot | 1.01367717 |
| 54 | MP0003878_abnormal_ear_physiology | 1.01367717 |
| 55 | MP0005332_abnormal_amino_acid | 1.01334960 |
| 56 | MP0004133_heterotaxia | 1.01266884 |
| 57 | MP0001905_abnormal_dopamine_level | 0.99856412 |
| 58 | MP0003693_abnormal_embryo_hatching | 0.98925190 |
| 59 | MP0003077_abnormal_cell_cycle | 0.97785982 |
| 60 | MP0003186_abnormal_redox_activity | 0.97286909 |
| 61 | MP0004043_abnormal_pH_regulation | 0.96328870 |
| 62 | MP0003936_abnormal_reproductive_system | 0.94538073 |
| 63 | MP0003111_abnormal_nucleus_morphology | 0.93793874 |
| 64 | MP0005220_abnormal_exocrine_pancreas | 0.90991616 |
| 65 | MP0002928_abnormal_bile_duct | 0.90764331 |
| 66 | MP0004885_abnormal_endolymph | 0.89935302 |
| 67 | MP0001119_abnormal_female_reproductive | 0.88967177 |
| 68 | MP0006036_abnormal_mitochondrial_physio | 0.87920644 |
| 69 | MP0002735_abnormal_chemical_nociception | 0.87498060 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.86224077 |
| 71 | MP0002210_abnormal_sex_determination | 0.85545958 |
| 72 | MP0008873_increased_physiological_sensi | 0.84875744 |
| 73 | MP0003950_abnormal_plasma_membrane | 0.83058420 |
| 74 | MP0009333_abnormal_splenocyte_physiolog | 0.82461343 |
| 75 | MP0001929_abnormal_gametogenesis | 0.80699464 |
| 76 | MP0002938_white_spotting | 0.78888308 |
| 77 | MP0005410_abnormal_fertilization | 0.78533425 |
| 78 | MP0003638_abnormal_response/metabolism_ | 0.78269999 |
| 79 | MP0001764_abnormal_homeostasis | 0.78224191 |
| 80 | MP0008789_abnormal_olfactory_epithelium | 0.78134870 |
| 81 | MP0005387_immune_system_phenotype | 0.77837454 |
| 82 | MP0001790_abnormal_immune_system | 0.77837454 |
| 83 | MP0001270_distended_abdomen | 0.77054245 |
| 84 | MP0002132_abnormal_respiratory_system | 0.75481630 |
| 85 | MP0001293_anophthalmia | 0.75083208 |
| 86 | MP0009745_abnormal_behavioral_response | 0.72666135 |
| 87 | MP0000653_abnormal_sex_gland | 0.72219186 |
| 88 | MP0003303_peritoneal_inflammation | 0.71969960 |
| 89 | MP0005085_abnormal_gallbladder_physiolo | 0.71929011 |
| 90 | MP0000427_abnormal_hair_cycle | 0.71189089 |
| 91 | MP0001800_abnormal_humoral_immune | 0.70938828 |
| 92 | MP0008932_abnormal_embryonic_tissue | 0.70738318 |
| 93 | MP0000358_abnormal_cell_content/ | 0.69946436 |
| 94 | MP0003937_abnormal_limbs/digits/tail_de | 0.69880323 |
| 95 | MP0006054_spinal_hemorrhage | 0.69606476 |
| 96 | MP0001663_abnormal_digestive_system | 0.69518016 |
| 97 | MP0006072_abnormal_retinal_apoptosis | 0.69103420 |
| 98 | MP0000049_abnormal_middle_ear | 0.68641422 |
| 99 | MP0005075_abnormal_melanosome_morpholog | 0.68626847 |
| 100 | MP0000631_abnormal_neuroendocrine_gland | 0.67672645 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.31615916 |
| 2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.11474767 |
| 3 | Increased CSF lactate (HP:0002490) | 4.08303106 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.94658069 |
| 5 | Acute encephalopathy (HP:0006846) | 3.68177416 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.63228552 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.53964620 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.44630525 |
| 9 | Aplastic anemia (HP:0001915) | 3.39824517 |
| 10 | Hepatic necrosis (HP:0002605) | 3.38442357 |
| 11 | Colon cancer (HP:0003003) | 3.27464333 |
| 12 | Increased serum lactate (HP:0002151) | 3.23451839 |
| 13 | Type II lissencephaly (HP:0007260) | 3.18374100 |
| 14 | Lipid accumulation in hepatocytes (HP:0006561) | 3.13309236 |
| 15 | Renal Fanconi syndrome (HP:0001994) | 3.05165832 |
| 16 | Cerebral edema (HP:0002181) | 2.99866074 |
| 17 | Increased intramyocellular lipid droplets (HP:0012240) | 2.96579713 |
| 18 | Pancreatic cysts (HP:0001737) | 2.89247586 |
| 19 | Oral leukoplakia (HP:0002745) | 2.73276920 |
| 20 | Lactic acidosis (HP:0003128) | 2.67342661 |
| 21 | Prostate neoplasm (HP:0100787) | 2.65715769 |
| 22 | Abnormality of alanine metabolism (HP:0010916) | 2.62471786 |
| 23 | Hyperalaninemia (HP:0003348) | 2.62471786 |
| 24 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.62471786 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.60174565 |
| 26 | Constricted visual fields (HP:0001133) | 2.59742631 |
| 27 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.57905990 |
| 28 | Optic disc pallor (HP:0000543) | 2.54458552 |
| 29 | Abnormal number of erythroid precursors (HP:0012131) | 2.52940298 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.51836695 |
| 31 | Generalized aminoaciduria (HP:0002909) | 2.50643876 |
| 32 | Absent thumb (HP:0009777) | 2.49670412 |
| 33 | True hermaphroditism (HP:0010459) | 2.49580965 |
| 34 | Severe combined immunodeficiency (HP:0004430) | 2.47503327 |
| 35 | Glycosuria (HP:0003076) | 2.35273542 |
| 36 | Abnormality of urine glucose concentration (HP:0011016) | 2.35273542 |
| 37 | Stomach cancer (HP:0012126) | 2.34822192 |
| 38 | Exertional dyspnea (HP:0002875) | 2.33317916 |
| 39 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.29502490 |
| 40 | Increased muscle lipid content (HP:0009058) | 2.27853701 |
| 41 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.25474705 |
| 42 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.25047529 |
| 43 | Abnormality of the pons (HP:0007361) | 2.19766594 |
| 44 | Lethargy (HP:0001254) | 2.19679105 |
| 45 | Abnormality of the ileum (HP:0001549) | 2.18385938 |
| 46 | Attenuation of retinal blood vessels (HP:0007843) | 2.17426261 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.17259687 |
| 48 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.17259687 |
| 49 | Respiratory failure (HP:0002878) | 2.16919851 |
| 50 | Meckel diverticulum (HP:0002245) | 2.16805083 |
| 51 | Chronic hepatic failure (HP:0100626) | 2.16084678 |
| 52 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.14842245 |
| 53 | Methylmalonic aciduria (HP:0012120) | 2.11554416 |
| 54 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.11424565 |
| 55 | Pancytopenia (HP:0001876) | 2.11256635 |
| 56 | Abnormality of midbrain morphology (HP:0002418) | 2.10801781 |
| 57 | Molar tooth sign on MRI (HP:0002419) | 2.10801781 |
| 58 | IgG deficiency (HP:0004315) | 2.09188991 |
| 59 | Hypoplasia of the radius (HP:0002984) | 2.08991218 |
| 60 | Reticulocytopenia (HP:0001896) | 2.07665715 |
| 61 | Hypophosphatemic rickets (HP:0004912) | 2.06155446 |
| 62 | Cleft eyelid (HP:0000625) | 2.04763887 |
| 63 | Concave nail (HP:0001598) | 2.04321841 |
| 64 | Abnormality of the prostate (HP:0008775) | 2.03803243 |
| 65 | Esophageal atresia (HP:0002032) | 2.03557722 |
| 66 | Thyroiditis (HP:0100646) | 2.03552124 |
| 67 | Cerebellar dysplasia (HP:0007033) | 2.02700431 |
| 68 | Leukodystrophy (HP:0002415) | 2.02530850 |
| 69 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.02466396 |
| 70 | Tubular atrophy (HP:0000092) | 2.00617348 |
| 71 | Asplenia (HP:0001746) | 1.98947843 |
| 72 | Medial flaring of the eyebrow (HP:0010747) | 1.98677612 |
| 73 | Nephronophthisis (HP:0000090) | 1.96994016 |
| 74 | Abnormality of the renal cortex (HP:0011035) | 1.96602086 |
| 75 | Methylmalonic acidemia (HP:0002912) | 1.95307618 |
| 76 | Hypoproteinemia (HP:0003075) | 1.94297967 |
| 77 | Respiratory difficulties (HP:0002880) | 1.93705605 |
| 78 | Renal cortical cysts (HP:0000803) | 1.93169523 |
| 79 | Cellular immunodeficiency (HP:0005374) | 1.91939609 |
| 80 | Macrocytic anemia (HP:0001972) | 1.90614495 |
| 81 | Abnormality of serum amino acid levels (HP:0003112) | 1.90522428 |
| 82 | Triphalangeal thumb (HP:0001199) | 1.89021034 |
| 83 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88995314 |
| 84 | Abnormality of the renal collecting system (HP:0004742) | 1.88825267 |
| 85 | Exercise intolerance (HP:0003546) | 1.88312202 |
| 86 | Abnormality of DNA repair (HP:0003254) | 1.87082658 |
| 87 | Combined immunodeficiency (HP:0005387) | 1.86464317 |
| 88 | Congenital, generalized hypertrichosis (HP:0004540) | 1.85280592 |
| 89 | Forearm undergrowth (HP:0009821) | 1.85022278 |
| 90 | Abnormality of the preputium (HP:0100587) | 1.83225102 |
| 91 | Abnormality of renal resorption (HP:0011038) | 1.82745621 |
| 92 | Microretrognathia (HP:0000308) | 1.81976005 |
| 93 | Duplicated collecting system (HP:0000081) | 1.81558840 |
| 94 | Retinal dysplasia (HP:0007973) | 1.80871723 |
| 95 | Sclerocornea (HP:0000647) | 1.80585293 |
| 96 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.79627839 |
| 97 | Abnormality of the labia minora (HP:0012880) | 1.78812541 |
| 98 | Progressive inability to walk (HP:0002505) | 1.78039460 |
| 99 | Hypoplasia of the uterus (HP:0000013) | 1.77873694 |
| 100 | Birth length less than 3rd percentile (HP:0003561) | 1.76854423 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BMPR1B | 3.47776412 |
| 2 | VRK2 | 3.04670497 |
| 3 | BUB1 | 2.97375513 |
| 4 | PBK | 2.96315792 |
| 5 | MAP4K1 | 2.77509972 |
| 6 | EIF2AK3 | 2.64042885 |
| 7 | FRK | 2.57550735 |
| 8 | NUAK1 | 2.32606841 |
| 9 | ZAK | 2.31450894 |
| 10 | KDR | 2.23233572 |
| 11 | BCKDK | 2.15723060 |
| 12 | CDK8 | 2.12822672 |
| 13 | VRK1 | 2.10500863 |
| 14 | CDK19 | 2.04180936 |
| 15 | GRK1 | 1.93265170 |
| 16 | TLK1 | 1.91425038 |
| 17 | TXK | 1.88466154 |
| 18 | MST4 | 1.85163482 |
| 19 | WNK3 | 1.76920294 |
| 20 | SRPK1 | 1.60720241 |
| 21 | OXSR1 | 1.60469773 |
| 22 | ADRBK2 | 1.57029158 |
| 23 | TGFBR1 | 1.53899916 |
| 24 | ITK | 1.53088126 |
| 25 | TAF1 | 1.41194752 |
| 26 | STK16 | 1.37373560 |
| 27 | TEC | 1.33299743 |
| 28 | CDC7 | 1.28272943 |
| 29 | WNK4 | 1.25514447 |
| 30 | TRIM28 | 1.24589794 |
| 31 | PRKCQ | 1.23599523 |
| 32 | TNIK | 1.23308499 |
| 33 | NME1 | 1.19739845 |
| 34 | MAP4K2 | 1.15963699 |
| 35 | MKNK2 | 1.15357369 |
| 36 | MUSK | 1.13865326 |
| 37 | PLK4 | 1.11073277 |
| 38 | FLT3 | 1.10078401 |
| 39 | MAPKAPK3 | 1.08022546 |
| 40 | INSRR | 1.00689369 |
| 41 | PLK3 | 1.00174388 |
| 42 | PRKD3 | 0.97595387 |
| 43 | NEK1 | 0.95276247 |
| 44 | PIK3CA | 0.86377769 |
| 45 | PLK1 | 0.84168096 |
| 46 | STK39 | 0.82460663 |
| 47 | FES | 0.80516005 |
| 48 | CHEK2 | 0.77407326 |
| 49 | WEE1 | 0.76777532 |
| 50 | IKBKB | 0.72670388 |
| 51 | STK38L | 0.71373469 |
| 52 | MKNK1 | 0.70740848 |
| 53 | NME2 | 0.69185399 |
| 54 | CDK9 | 0.68749251 |
| 55 | TSSK6 | 0.67534275 |
| 56 | PDK2 | 0.67232228 |
| 57 | STK4 | 0.66150266 |
| 58 | CSNK1G1 | 0.65747722 |
| 59 | DAPK1 | 0.64807836 |
| 60 | ATR | 0.62410654 |
| 61 | TAOK3 | 0.60415080 |
| 62 | CDK3 | 0.58472915 |
| 63 | DYRK2 | 0.58324282 |
| 64 | FGFR1 | 0.57714719 |
| 65 | AKT3 | 0.55791618 |
| 66 | PRKCE | 0.55410576 |
| 67 | MAP3K12 | 0.53203922 |
| 68 | MAPKAPK5 | 0.52499037 |
| 69 | ADRBK1 | 0.52314986 |
| 70 | ZAP70 | 0.51416143 |
| 71 | CSNK1G3 | 0.51413649 |
| 72 | EIF2AK1 | 0.50294762 |
| 73 | LIMK1 | 0.50016296 |
| 74 | BCR | 0.48676601 |
| 75 | PIM2 | 0.46837742 |
| 76 | CSNK2A2 | 0.46750390 |
| 77 | RPS6KA5 | 0.46529246 |
| 78 | FGFR2 | 0.46026222 |
| 79 | ERBB4 | 0.45915154 |
| 80 | CSNK1G2 | 0.45878501 |
| 81 | EIF2AK2 | 0.45432872 |
| 82 | BRSK2 | 0.44414870 |
| 83 | AURKA | 0.42690051 |
| 84 | LCK | 0.42316449 |
| 85 | CSNK2A1 | 0.41824371 |
| 86 | PRKCG | 0.40785218 |
| 87 | PIK3CG | 0.40549021 |
| 88 | AURKB | 0.40197206 |
| 89 | SYK | 0.39946741 |
| 90 | PASK | 0.39768072 |
| 91 | SIK2 | 0.39419632 |
| 92 | ATM | 0.38288461 |
| 93 | RPS6KA4 | 0.36112404 |
| 94 | PLK2 | 0.35414095 |
| 95 | MAPK13 | 0.34744826 |
| 96 | IGF1R | 0.34114068 |
| 97 | PNCK | 0.33779896 |
| 98 | BTK | 0.31764395 |
| 99 | PIM1 | 0.31595149 |
| 100 | GRK5 | 0.31153097 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.03397506 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.49443550 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.41369085 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 3.24954707 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.03798836 |
| 6 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.88807878 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.78580209 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.51250682 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.34315298 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.34233272 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.21166264 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.19100201 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.11902465 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 2.06734296 |
| 15 | Mismatch repair_Homo sapiens_hsa03430 | 2.01442718 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 1.95566362 |
| 17 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.90803268 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.84324175 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.81872533 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.81076380 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.73137379 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.71777741 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.57884925 |
| 24 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.55940773 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.54532107 |
| 26 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.48845584 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.38121523 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.36293693 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.35536165 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.33971343 |
| 31 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.32414806 |
| 32 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.26651096 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.21863205 |
| 34 | Spliceosome_Homo sapiens_hsa03040 | 1.21460230 |
| 35 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.20047118 |
| 36 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.13776867 |
| 37 | Purine metabolism_Homo sapiens_hsa00230 | 1.12881215 |
| 38 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.11564399 |
| 39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.07028747 |
| 40 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.06995729 |
| 41 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.02205108 |
| 42 | RNA transport_Homo sapiens_hsa03013 | 1.01144865 |
| 43 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.01086337 |
| 44 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.95111012 |
| 45 | Phototransduction_Homo sapiens_hsa04744 | 0.93885155 |
| 46 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.88877248 |
| 47 | Peroxisome_Homo sapiens_hsa04146 | 0.86221967 |
| 48 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.85413824 |
| 49 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.83696493 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.83253959 |
| 51 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.82084465 |
| 52 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.81060526 |
| 53 | Sulfur relay system_Homo sapiens_hsa04122 | 0.76487387 |
| 54 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.76427080 |
| 55 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.75058847 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.74989003 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.73473026 |
| 58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.73471887 |
| 59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.72456659 |
| 60 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.68555449 |
| 61 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.67454885 |
| 62 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.65928130 |
| 63 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.64888439 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61994545 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.61198890 |
| 66 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.60779576 |
| 67 | Viral myocarditis_Homo sapiens_hsa05416 | 0.60285102 |
| 68 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.59394477 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.56499535 |
| 70 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.56364542 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56015791 |
| 72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.55520995 |
| 73 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.55445556 |
| 74 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.54520215 |
| 75 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.52655707 |
| 76 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.49745987 |
| 77 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.45627706 |
| 78 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.40936782 |
| 79 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.40549383 |
| 80 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.39822425 |
| 81 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.38959940 |
| 82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.38750999 |
| 83 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38615665 |
| 84 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36894511 |
| 85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.34967871 |
| 86 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.33122336 |
| 87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32569343 |
| 88 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.31700861 |
| 89 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.30687468 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.30644337 |
| 91 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.30631487 |
| 92 | Leishmaniasis_Homo sapiens_hsa05140 | 0.25892539 |
| 93 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.25140772 |
| 94 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.24543364 |
| 95 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.23163113 |
| 96 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.22504893 |
| 97 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.21265271 |
| 98 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.19715729 |
| 99 | Measles_Homo sapiens_hsa05162 | 0.19144684 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.18785792 |

