

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 7.92960893 |
| 2 | viral transcription (GO:0019083) | 6.16473715 |
| 3 | DNA deamination (GO:0045006) | 6.00095133 |
| 4 | translational termination (GO:0006415) | 5.93115819 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.52710191 |
| 6 | ATP synthesis coupled proton transport (GO:0015986) | 5.52710191 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.33507319 |
| 8 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.28478982 |
| 9 | ribosomal small subunit biogenesis (GO:0042274) | 5.25142294 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.23013658 |
| 11 | translational elongation (GO:0006414) | 5.21155279 |
| 12 | cotranslational protein targeting to membrane (GO:0006613) | 5.14338877 |
| 13 | protein targeting to ER (GO:0045047) | 5.12331790 |
| 14 | maturation of SSU-rRNA (GO:0030490) | 5.11759138 |
| 15 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.07612735 |
| 16 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.90066158 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 4.87371936 |
| 18 | protein localization to endoplasmic reticulum (GO:0070972) | 4.82291336 |
| 19 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.79702627 |
| 20 | viral life cycle (GO:0019058) | 4.49630309 |
| 21 | cellular protein complex disassembly (GO:0043624) | 4.46851276 |
| 22 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.40231197 |
| 23 | protein neddylation (GO:0045116) | 4.36986903 |
| 24 | ribosomal large subunit biogenesis (GO:0042273) | 4.35480771 |
| 25 | behavioral response to nicotine (GO:0035095) | 4.24548202 |
| 26 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.21750008 |
| 27 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.21750008 |
| 28 | NADH dehydrogenase complex assembly (GO:0010257) | 4.21750008 |
| 29 | protein complex biogenesis (GO:0070271) | 4.18780635 |
| 30 | respiratory electron transport chain (GO:0022904) | 4.13975591 |
| 31 | cytidine deamination (GO:0009972) | 4.12581597 |
| 32 | cytidine metabolic process (GO:0046087) | 4.12581597 |
| 33 | cytidine catabolic process (GO:0006216) | 4.12581597 |
| 34 | translational initiation (GO:0006413) | 4.12549349 |
| 35 | electron transport chain (GO:0022900) | 4.12059925 |
| 36 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.81315871 |
| 37 | translation (GO:0006412) | 3.80021173 |
| 38 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.72417790 |
| 39 | protein complex disassembly (GO:0043241) | 3.71042136 |
| 40 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.68912802 |
| 41 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.65866266 |
| 42 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.56583099 |
| 43 | macromolecular complex disassembly (GO:0032984) | 3.54218618 |
| 44 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.43927471 |
| 45 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.38640665 |
| 46 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.38640665 |
| 47 | cellular component biogenesis (GO:0044085) | 3.33635581 |
| 48 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.31687832 |
| 49 | protein targeting to membrane (GO:0006612) | 3.31203492 |
| 50 | sequestering of actin monomers (GO:0042989) | 3.29635009 |
| 51 | response to pheromone (GO:0019236) | 3.25522256 |
| 52 | respiratory chain complex IV assembly (GO:0008535) | 3.22943144 |
| 53 | ubiquinone biosynthetic process (GO:0006744) | 3.19305658 |
| 54 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.15226831 |
| 55 | mRNA catabolic process (GO:0006402) | 3.12993795 |
| 56 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.09954157 |
| 57 | ATP biosynthetic process (GO:0006754) | 3.07388355 |
| 58 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.06644414 |
| 59 | proteasome assembly (GO:0043248) | 3.06578635 |
| 60 | intracellular protein transmembrane import (GO:0044743) | 3.05812636 |
| 61 | GTP biosynthetic process (GO:0006183) | 3.04288599 |
| 62 | cytochrome complex assembly (GO:0017004) | 3.00070190 |
| 63 | ncRNA 3-end processing (GO:0043628) | 2.98991126 |
| 64 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.97482528 |
| 65 | termination of RNA polymerase III transcription (GO:0006386) | 2.95695711 |
| 66 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.95695711 |
| 67 | ubiquinone metabolic process (GO:0006743) | 2.93571075 |
| 68 | RNA catabolic process (GO:0006401) | 2.92750570 |
| 69 | chromatin remodeling at centromere (GO:0031055) | 2.91426972 |
| 70 | pseudouridine synthesis (GO:0001522) | 2.90421501 |
| 71 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.86274516 |
| 72 | hydrogen ion transmembrane transport (GO:1902600) | 2.85399047 |
| 73 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.83680955 |
| 74 | platelet dense granule organization (GO:0060155) | 2.83385095 |
| 75 | rRNA processing (GO:0006364) | 2.83333060 |
| 76 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.82699630 |
| 77 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.79875645 |
| 78 | base-excision repair, AP site formation (GO:0006285) | 2.79806290 |
| 79 | rRNA metabolic process (GO:0016072) | 2.79158460 |
| 80 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.78335182 |
| 81 | somite development (GO:0061053) | 2.76911171 |
| 82 | positive regulation of protein homodimerization activity (GO:0090073) | 2.72218190 |
| 83 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.71158468 |
| 84 | deoxyribonucleotide catabolic process (GO:0009264) | 2.70250095 |
| 85 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.69968744 |
| 86 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.69926769 |
| 87 | quinone biosynthetic process (GO:1901663) | 2.69420470 |
| 88 | mannosylation (GO:0097502) | 2.68770581 |
| 89 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.68426384 |
| 90 | UTP metabolic process (GO:0046051) | 2.68099301 |
| 91 | deoxyribose phosphate catabolic process (GO:0046386) | 2.66827727 |
| 92 | CENP-A containing nucleosome assembly (GO:0034080) | 2.66777861 |
| 93 | UTP biosynthetic process (GO:0006228) | 2.66026826 |
| 94 | establishment of protein localization to mitochondrion (GO:0072655) | 2.64361207 |
| 95 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 2.62364314 |
| 96 | protein-cofactor linkage (GO:0018065) | 2.62116020 |
| 97 | proton transport (GO:0015992) | 2.61529883 |
| 98 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.60976038 |
| 99 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.60976038 |
| 100 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.60976038 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.37565995 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.98916336 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.59402441 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.40390605 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.28477905 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.16176631 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.02779494 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.92101356 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.89562090 |
| 10 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.85765323 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.64519685 |
| 12 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.53338772 |
| 13 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.51724560 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.45469221 |
| 15 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.43784048 |
| 16 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.41946766 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.33622736 |
| 18 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.33136162 |
| 19 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.21913885 |
| 20 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.16479317 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.07430086 |
| 22 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.94541536 |
| 23 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.93986904 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.85079537 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.85059598 |
| 26 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.84666001 |
| 27 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.83873714 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.79086853 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.70836587 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.69013966 |
| 31 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.68397799 |
| 32 | EWS_26573619_Chip-Seq_HEK293_Human | 1.66754407 |
| 33 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62436020 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.57150451 |
| 35 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.56384052 |
| 36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.53255099 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.50852278 |
| 38 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.40880908 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.40294354 |
| 40 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.38688848 |
| 41 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.38302255 |
| 42 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.37544079 |
| 43 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.37344955 |
| 44 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.34219200 |
| 45 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.33100204 |
| 46 | FUS_26573619_Chip-Seq_HEK293_Human | 1.32420465 |
| 47 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.30999154 |
| 48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.30758288 |
| 49 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.28926745 |
| 50 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.28926745 |
| 51 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.25443126 |
| 52 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.24153653 |
| 53 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.23799516 |
| 54 | NCOR_22424771_ChIP-Seq_293T_Human | 1.22450962 |
| 55 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.22349892 |
| 56 | AR_20517297_ChIP-Seq_VCAP_Human | 1.22113763 |
| 57 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.20114324 |
| 58 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.19168804 |
| 59 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.16930049 |
| 60 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.16802583 |
| 61 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.16513899 |
| 62 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.16215594 |
| 63 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.16025269 |
| 64 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.12275546 |
| 65 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.12249377 |
| 66 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11441196 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11441196 |
| 68 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.10622670 |
| 69 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.08437600 |
| 70 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07999170 |
| 71 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07491512 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.07374015 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.07213361 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.05557221 |
| 75 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.05299751 |
| 76 | ERA_21632823_ChIP-Seq_H3396_Human | 1.04237307 |
| 77 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.04177209 |
| 78 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.04123072 |
| 79 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.02463930 |
| 80 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.00530141 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00173160 |
| 82 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98892102 |
| 83 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.97801967 |
| 84 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.97113272 |
| 85 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.96671099 |
| 86 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.96144012 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.95745680 |
| 88 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.94837580 |
| 89 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.93967771 |
| 90 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92100975 |
| 91 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91343961 |
| 92 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.90412445 |
| 93 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.89831477 |
| 94 | P300_19829295_ChIP-Seq_ESCs_Human | 0.89204100 |
| 95 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.89152285 |
| 96 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.88993049 |
| 97 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.88459204 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88443704 |
| 99 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.88399220 |
| 100 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.86387632 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.38944548 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.27160898 |
| 3 | MP0003878_abnormal_ear_physiology | 2.97583456 |
| 4 | MP0005377_hearing/vestibular/ear_phenot | 2.97583456 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 2.70782138 |
| 6 | MP0005084_abnormal_gallbladder_morpholo | 2.63103064 |
| 7 | MP0008877_abnormal_DNA_methylation | 2.52042706 |
| 8 | MP0002138_abnormal_hepatobiliary_system | 2.48613986 |
| 9 | MP0002102_abnormal_ear_morphology | 2.42946283 |
| 10 | MP0005671_abnormal_response_to | 2.28150789 |
| 11 | MP0000372_irregular_coat_pigmentation | 2.09920693 |
| 12 | MP0003646_muscle_fatigue | 2.08346731 |
| 13 | MP0009333_abnormal_splenocyte_physiolog | 2.03003855 |
| 14 | MP0002653_abnormal_ependyma_morphology | 1.91174679 |
| 15 | MP0001485_abnormal_pinna_reflex | 1.87273879 |
| 16 | MP0008872_abnormal_physiological_respon | 1.82103973 |
| 17 | MP0005646_abnormal_pituitary_gland | 1.81444587 |
| 18 | MP0006072_abnormal_retinal_apoptosis | 1.79658841 |
| 19 | MP0004885_abnormal_endolymph | 1.75060675 |
| 20 | MP0003787_abnormal_imprinting | 1.60434190 |
| 21 | MP0005645_abnormal_hypothalamus_physiol | 1.59283495 |
| 22 | MP0003122_maternal_imprinting | 1.53871070 |
| 23 | MP0002638_abnormal_pupillary_reflex | 1.53013558 |
| 24 | MP0004142_abnormal_muscle_tone | 1.52989654 |
| 25 | MP0005551_abnormal_eye_electrophysiolog | 1.51533501 |
| 26 | MP0005075_abnormal_melanosome_morpholog | 1.50557019 |
| 27 | MP0001529_abnormal_vocalization | 1.45410709 |
| 28 | MP0001293_anophthalmia | 1.45322427 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.44425994 |
| 30 | MP0004147_increased_porphyrin_level | 1.42005573 |
| 31 | MP0001873_stomach_inflammation | 1.35388096 |
| 32 | MP0002163_abnormal_gland_morphology | 1.34115604 |
| 33 | MP0003786_premature_aging | 1.33298574 |
| 34 | MP0000631_abnormal_neuroendocrine_gland | 1.31283387 |
| 35 | MP0003186_abnormal_redox_activity | 1.30190679 |
| 36 | MP0005389_reproductive_system_phenotype | 1.29980581 |
| 37 | MP0002160_abnormal_reproductive_system | 1.27792171 |
| 38 | MP0002938_white_spotting | 1.26425086 |
| 39 | MP0001764_abnormal_homeostasis | 1.25814920 |
| 40 | MP0002277_abnormal_respiratory_mucosa | 1.21725022 |
| 41 | MP0001986_abnormal_taste_sensitivity | 1.21463436 |
| 42 | MP0003718_maternal_effect | 1.19152446 |
| 43 | MP0008875_abnormal_xenobiotic_pharmacok | 1.19012587 |
| 44 | MP0001905_abnormal_dopamine_level | 1.18745318 |
| 45 | MP0000049_abnormal_middle_ear | 1.18499647 |
| 46 | MP0002876_abnormal_thyroid_physiology | 1.16267706 |
| 47 | MP0001835_abnormal_antigen_presentation | 1.16202086 |
| 48 | MP0001919_abnormal_reproductive_system | 1.15569013 |
| 49 | MP0002736_abnormal_nociception_after | 1.15110794 |
| 50 | MP0003567_abnormal_fetal_cardiomyocyte | 1.10829578 |
| 51 | MP0009785_altered_susceptibility_to | 1.08858463 |
| 52 | MP0004742_abnormal_vestibular_system | 1.08200558 |
| 53 | MP0008789_abnormal_olfactory_epithelium | 1.07630586 |
| 54 | MP0006276_abnormal_autonomic_nervous | 1.06121093 |
| 55 | MP0002234_abnormal_pharynx_morphology | 1.04475858 |
| 56 | MP0005253_abnormal_eye_physiology | 1.03116974 |
| 57 | MP0008995_early_reproductive_senescence | 1.02273207 |
| 58 | MP0008058_abnormal_DNA_repair | 1.02263169 |
| 59 | MP0002095_abnormal_skin_pigmentation | 1.00423533 |
| 60 | MP0002272_abnormal_nervous_system | 0.99634209 |
| 61 | MP0001188_hyperpigmentation | 0.98229324 |
| 62 | MP0003283_abnormal_digestive_organ | 0.96998687 |
| 63 | MP0004145_abnormal_muscle_electrophysio | 0.95779311 |
| 64 | MP0003880_abnormal_central_pattern | 0.94183224 |
| 65 | MP0002210_abnormal_sex_determination | 0.90743044 |
| 66 | MP0000685_abnormal_immune_system | 0.89761489 |
| 67 | MP0003011_delayed_dark_adaptation | 0.88719161 |
| 68 | MP0000026_abnormal_inner_ear | 0.88501099 |
| 69 | MP0001800_abnormal_humoral_immune | 0.87186642 |
| 70 | MP0002733_abnormal_thermal_nociception | 0.85984895 |
| 71 | MP0005379_endocrine/exocrine_gland_phen | 0.85877624 |
| 72 | MP0001970_abnormal_pain_threshold | 0.85753365 |
| 73 | MP0008775_abnormal_heart_ventricle | 0.84961899 |
| 74 | MP0006036_abnormal_mitochondrial_physio | 0.83005552 |
| 75 | MP0003121_genomic_imprinting | 0.82901211 |
| 76 | MP0005195_abnormal_posterior_eye | 0.80923685 |
| 77 | MP0002148_abnormal_hypersensitivity_rea | 0.77225127 |
| 78 | MP0001963_abnormal_hearing_physiology | 0.75818711 |
| 79 | MP0001929_abnormal_gametogenesis | 0.75779083 |
| 80 | MP0002006_tumorigenesis | 0.75392101 |
| 81 | MP0000653_abnormal_sex_gland | 0.74698471 |
| 82 | MP0003763_abnormal_thymus_physiology | 0.73420918 |
| 83 | MP0002752_abnormal_somatic_nervous | 0.73178223 |
| 84 | MP0005636_abnormal_mineral_homeostasis | 0.71599481 |
| 85 | MP0001145_abnormal_male_reproductive | 0.71109494 |
| 86 | MP0002166_altered_tumor_susceptibility | 0.69991331 |
| 87 | MP0009745_abnormal_behavioral_response | 0.69114835 |
| 88 | MP0001348_abnormal_lacrimal_gland | 0.68877007 |
| 89 | MP0008007_abnormal_cellular_replicative | 0.67619527 |
| 90 | MP0005387_immune_system_phenotype | 0.67239380 |
| 91 | MP0001790_abnormal_immune_system | 0.67239380 |
| 92 | MP0003937_abnormal_limbs/digits/tail_de | 0.67094892 |
| 93 | MP0003195_calcinosis | 0.66079431 |
| 94 | MP0000230_abnormal_systemic_arterial | 0.64815915 |
| 95 | MP0000613_abnormal_salivary_gland | 0.64309198 |
| 96 | MP0001119_abnormal_female_reproductive | 0.64280900 |
| 97 | MP0003136_yellow_coat_color | 0.64199248 |
| 98 | MP0001663_abnormal_digestive_system | 0.63893454 |
| 99 | MP0001440_abnormal_grooming_behavior | 0.62163967 |
| 100 | MP0006035_abnormal_mitochondrial_morpho | 0.61821666 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.82956585 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.58393621 |
| 3 | Reticulocytopenia (HP:0001896) | 4.27640339 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.21284841 |
| 5 | Acute encephalopathy (HP:0006846) | 4.21030254 |
| 6 | Increased CSF lactate (HP:0002490) | 4.11478790 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.95289344 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.82339980 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.81644763 |
| 10 | Congenital stationary night blindness (HP:0007642) | 3.54838800 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.54107424 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.49468128 |
| 13 | Hepatic necrosis (HP:0002605) | 3.43555168 |
| 14 | Abnormality of midbrain morphology (HP:0002418) | 3.37401915 |
| 15 | Molar tooth sign on MRI (HP:0002419) | 3.37401915 |
| 16 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.34286714 |
| 17 | Cerebral edema (HP:0002181) | 3.32961187 |
| 18 | Pancreatic fibrosis (HP:0100732) | 3.24763810 |
| 19 | Macrocytic anemia (HP:0001972) | 3.15589136 |
| 20 | Pancreatic cysts (HP:0001737) | 3.09857190 |
| 21 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.04784647 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 3.04160562 |
| 23 | Abnormal number of erythroid precursors (HP:0012131) | 3.02254014 |
| 24 | Colon cancer (HP:0003003) | 2.99638269 |
| 25 | True hermaphroditism (HP:0010459) | 2.93500781 |
| 26 | 3-Methylglutaconic aciduria (HP:0003535) | 2.89111453 |
| 27 | Increased intramyocellular lipid droplets (HP:0012240) | 2.78899409 |
| 28 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.76190724 |
| 29 | Nephronophthisis (HP:0000090) | 2.69212139 |
| 30 | Optic disc pallor (HP:0000543) | 2.68617158 |
| 31 | Increased serum lactate (HP:0002151) | 2.67841404 |
| 32 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.65627309 |
| 33 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.63639488 |
| 34 | Asplenia (HP:0001746) | 2.59866693 |
| 35 | Lactic acidosis (HP:0003128) | 2.59681298 |
| 36 | Septo-optic dysplasia (HP:0100842) | 2.54373886 |
| 37 | Exertional dyspnea (HP:0002875) | 2.53756764 |
| 38 | Aplastic anemia (HP:0001915) | 2.49546157 |
| 39 | Hyperglycinemia (HP:0002154) | 2.47393459 |
| 40 | Pallor (HP:0000980) | 2.44514457 |
| 41 | Medial flaring of the eyebrow (HP:0010747) | 2.40630662 |
| 42 | Leukodystrophy (HP:0002415) | 2.34869584 |
| 43 | Lethargy (HP:0001254) | 2.33570581 |
| 44 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.32893310 |
| 45 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.32030112 |
| 46 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.32030112 |
| 47 | Increased muscle lipid content (HP:0009058) | 2.31798941 |
| 48 | Respiratory failure (HP:0002878) | 2.31580647 |
| 49 | Abolished electroretinogram (ERG) (HP:0000550) | 2.29781021 |
| 50 | Methylmalonic acidemia (HP:0002912) | 2.28198899 |
| 51 | Absent thumb (HP:0009777) | 2.27528391 |
| 52 | Respiratory difficulties (HP:0002880) | 2.25261644 |
| 53 | Absent/shortened dynein arms (HP:0200106) | 2.17405754 |
| 54 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.17405754 |
| 55 | Abnormality of renal resorption (HP:0011038) | 2.15573067 |
| 56 | Partial duplication of thumb phalanx (HP:0009944) | 2.13683045 |
| 57 | Stenosis of the external auditory canal (HP:0000402) | 2.13564776 |
| 58 | Exercise intolerance (HP:0003546) | 2.10330597 |
| 59 | Sclerocornea (HP:0000647) | 2.10205395 |
| 60 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.10051361 |
| 61 | Abnormality of the renal medulla (HP:0100957) | 2.07084798 |
| 62 | Decreased central vision (HP:0007663) | 2.05441726 |
| 63 | Hyperphosphaturia (HP:0003109) | 2.05409315 |
| 64 | Abnormality of urine glucose concentration (HP:0011016) | 2.05364736 |
| 65 | Glycosuria (HP:0003076) | 2.05364736 |
| 66 | Constricted visual fields (HP:0001133) | 2.04947509 |
| 67 | Pendular nystagmus (HP:0012043) | 2.03897087 |
| 68 | Abnormality of the renal cortex (HP:0011035) | 2.03364257 |
| 69 | Postaxial foot polydactyly (HP:0001830) | 1.98965462 |
| 70 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.98820124 |
| 71 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.98820124 |
| 72 | Abnormality of B cell number (HP:0010975) | 1.94854294 |
| 73 | Congenital, generalized hypertrichosis (HP:0004540) | 1.94720158 |
| 74 | Methylmalonic aciduria (HP:0012120) | 1.94680568 |
| 75 | Cystic liver disease (HP:0006706) | 1.92431274 |
| 76 | Abnormal drinking behavior (HP:0030082) | 1.90822640 |
| 77 | Polydipsia (HP:0001959) | 1.90822640 |
| 78 | IgG deficiency (HP:0004315) | 1.90677388 |
| 79 | Partial duplication of the phalanx of hand (HP:0009999) | 1.87238742 |
| 80 | Pancytopenia (HP:0001876) | 1.86377227 |
| 81 | Type 2 muscle fiber atrophy (HP:0003554) | 1.86014437 |
| 82 | Triphalangeal thumb (HP:0001199) | 1.84917144 |
| 83 | Supernumerary spleens (HP:0009799) | 1.81438170 |
| 84 | Tubular atrophy (HP:0000092) | 1.79481084 |
| 85 | Congenital hepatic fibrosis (HP:0002612) | 1.78582228 |
| 86 | Optic nerve hypoplasia (HP:0000609) | 1.78309705 |
| 87 | Adrenal hypoplasia (HP:0000835) | 1.77518786 |
| 88 | Type I transferrin isoform profile (HP:0003642) | 1.77284017 |
| 89 | Abnormality of the labia minora (HP:0012880) | 1.76784598 |
| 90 | Congenital primary aphakia (HP:0007707) | 1.76163873 |
| 91 | Abnormal ciliary motility (HP:0012262) | 1.75583452 |
| 92 | Attenuation of retinal blood vessels (HP:0007843) | 1.74565404 |
| 93 | Type II lissencephaly (HP:0007260) | 1.73297777 |
| 94 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.72585849 |
| 95 | Abnormality of glycine metabolism (HP:0010895) | 1.72585849 |
| 96 | Gait imbalance (HP:0002141) | 1.72233503 |
| 97 | Muscle fiber atrophy (HP:0100295) | 1.71869034 |
| 98 | Increased IgM level (HP:0003496) | 1.71550213 |
| 99 | Anencephaly (HP:0002323) | 1.70643438 |
| 100 | Renal cortical cysts (HP:0000803) | 1.70519994 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCKDK | 3.82755896 |
| 2 | VRK2 | 3.61416623 |
| 3 | STK16 | 3.04029644 |
| 4 | NUAK1 | 2.53656751 |
| 5 | KDR | 2.47500228 |
| 6 | ADRBK2 | 2.42983993 |
| 7 | WNK4 | 2.40448343 |
| 8 | VRK1 | 2.38284845 |
| 9 | PASK | 2.35598556 |
| 10 | TXK | 2.26865942 |
| 11 | GRK1 | 2.26404797 |
| 12 | CDK19 | 2.20841963 |
| 13 | PINK1 | 2.15118408 |
| 14 | BMPR1B | 2.10729259 |
| 15 | ZAK | 2.08262055 |
| 16 | TLK1 | 1.94807213 |
| 17 | BUB1 | 1.91837256 |
| 18 | MAP4K2 | 1.83519357 |
| 19 | DYRK2 | 1.71064074 |
| 20 | TAOK3 | 1.61836688 |
| 21 | TESK2 | 1.54906594 |
| 22 | MAP4K1 | 1.39693402 |
| 23 | WNK3 | 1.37335055 |
| 24 | STK39 | 1.32421605 |
| 25 | PIK3CA | 1.26240618 |
| 26 | TIE1 | 1.26053524 |
| 27 | TAF1 | 1.24207765 |
| 28 | TRIM28 | 1.22723381 |
| 29 | CAMKK2 | 1.17754894 |
| 30 | FRK | 1.11170717 |
| 31 | NEK1 | 1.07578393 |
| 32 | TEC | 1.05251023 |
| 33 | ITK | 1.04531754 |
| 34 | LIMK1 | 1.04175807 |
| 35 | MAP3K12 | 0.99822000 |
| 36 | PLK3 | 0.96627834 |
| 37 | PRKCQ | 0.92370372 |
| 38 | GRK6 | 0.92349855 |
| 39 | OXSR1 | 0.91854214 |
| 40 | PLK4 | 0.91813552 |
| 41 | NME1 | 0.91783302 |
| 42 | CDC7 | 0.91131318 |
| 43 | MAP2K7 | 0.90215564 |
| 44 | TGFBR1 | 0.89581270 |
| 45 | MUSK | 0.88499520 |
| 46 | CDK8 | 0.84430584 |
| 47 | BCR | 0.82984414 |
| 48 | CSNK1G3 | 0.78366638 |
| 49 | AURKB | 0.78073059 |
| 50 | MKNK1 | 0.77005510 |
| 51 | MAP3K11 | 0.75635056 |
| 52 | CSNK1G2 | 0.72306130 |
| 53 | SYK | 0.71562039 |
| 54 | BTK | 0.71299181 |
| 55 | MKNK2 | 0.71298357 |
| 56 | DAPK3 | 0.71273767 |
| 57 | INSRR | 0.70399453 |
| 58 | NME2 | 0.68303662 |
| 59 | MAPK15 | 0.68159582 |
| 60 | CSNK1G1 | 0.67368950 |
| 61 | ATR | 0.66010733 |
| 62 | MAPK13 | 0.65981109 |
| 63 | CHEK2 | 0.65555336 |
| 64 | PLK1 | 0.62803027 |
| 65 | PRKCG | 0.62429794 |
| 66 | AURKA | 0.59264590 |
| 67 | CAMK1 | 0.58014407 |
| 68 | CAMKK1 | 0.57633768 |
| 69 | ERBB3 | 0.56731975 |
| 70 | CSNK2A1 | 0.56453767 |
| 71 | PLK2 | 0.56381080 |
| 72 | CSNK2A2 | 0.55949856 |
| 73 | SRPK1 | 0.55496244 |
| 74 | MAPKAPK3 | 0.55244403 |
| 75 | DAPK1 | 0.51468652 |
| 76 | MAP2K6 | 0.49710336 |
| 77 | PRKCE | 0.49636915 |
| 78 | RPS6KA5 | 0.49045968 |
| 79 | IKBKB | 0.48936537 |
| 80 | MST4 | 0.48788794 |
| 81 | KIT | 0.48772283 |
| 82 | MAPKAPK5 | 0.47908227 |
| 83 | MAP3K4 | 0.47550920 |
| 84 | PBK | 0.46693862 |
| 85 | RPS6KB2 | 0.46280491 |
| 86 | LCK | 0.46221096 |
| 87 | OBSCN | 0.45664981 |
| 88 | ACVR1B | 0.45202208 |
| 89 | PRKACA | 0.44523493 |
| 90 | ADRBK1 | 0.42763120 |
| 91 | TNK2 | 0.42622355 |
| 92 | NEK2 | 0.41234761 |
| 93 | EPHA4 | 0.40050416 |
| 94 | PRKCA | 0.39755744 |
| 95 | GRK5 | 0.36283755 |
| 96 | IGF1R | 0.35925413 |
| 97 | ILK | 0.34514815 |
| 98 | RPS6KA4 | 0.34330928 |
| 99 | TNIK | 0.34321774 |
| 100 | WEE1 | 0.34098975 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.26079289 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.12270725 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.72374553 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.44897708 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 2.92060929 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.48458361 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.41232332 |
| 8 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.33282916 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 2.22818919 |
| 10 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.01068438 |
| 11 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.93165524 |
| 12 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.88389613 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.83562046 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.80991083 |
| 15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.74688545 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.72290164 |
| 17 | Asthma_Homo sapiens_hsa05310 | 1.66245984 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.64703720 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.58193920 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.57732891 |
| 21 | DNA replication_Homo sapiens_hsa03030 | 1.55021727 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.48551450 |
| 23 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.47980851 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.43259092 |
| 25 | Base excision repair_Homo sapiens_hsa03410 | 1.42967275 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.36288699 |
| 27 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.32944984 |
| 28 | Allograft rejection_Homo sapiens_hsa05330 | 1.32763970 |
| 29 | Phototransduction_Homo sapiens_hsa04744 | 1.31472109 |
| 30 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.28250005 |
| 31 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.27831924 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.27744241 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.26758222 |
| 34 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.23256766 |
| 35 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.22470248 |
| 36 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.16155674 |
| 37 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.15385373 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 1.15021092 |
| 39 | Spliceosome_Homo sapiens_hsa03040 | 1.11954205 |
| 40 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.04682157 |
| 41 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.04644877 |
| 42 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.02547563 |
| 43 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.00804508 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.00726179 |
| 45 | RNA transport_Homo sapiens_hsa03013 | 0.99345796 |
| 46 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.97986362 |
| 47 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.92835023 |
| 48 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90422140 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.88183122 |
| 50 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.87435496 |
| 51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.83720836 |
| 52 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.80198654 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78358538 |
| 54 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.77075122 |
| 55 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.75664294 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.74734735 |
| 57 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74101434 |
| 58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72109747 |
| 59 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.71180670 |
| 60 | Sulfur relay system_Homo sapiens_hsa04122 | 0.70057876 |
| 61 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.67848919 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64558400 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62976580 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61430855 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.60540508 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.60410929 |
| 67 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.56435283 |
| 68 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.55912972 |
| 69 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.54939822 |
| 70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.53555410 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52196282 |
| 72 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.51102097 |
| 73 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.50974511 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.49457221 |
| 75 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.49246744 |
| 76 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48986243 |
| 77 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.48945573 |
| 78 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.48226325 |
| 79 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46929866 |
| 80 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44846036 |
| 81 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.44510155 |
| 82 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.44227339 |
| 83 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.44021746 |
| 84 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.42585124 |
| 85 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.42321794 |
| 86 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.39963494 |
| 87 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.38052433 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37193782 |
| 89 | Nicotine addiction_Homo sapiens_hsa05033 | 0.36492063 |
| 90 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33141479 |
| 91 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.29317060 |
| 92 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.28284052 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.26520553 |
| 94 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.25377544 |
| 95 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.24443433 |
| 96 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.23240277 |
| 97 | Morphine addiction_Homo sapiens_hsa05032 | 0.21259556 |
| 98 | Taste transduction_Homo sapiens_hsa04742 | 0.18466885 |
| 99 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.17324898 |
| 100 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.15976502 |

