RRAD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)9.29221940
2cardiac myofibril assembly (GO:0055003)9.05385862
3cilium or flagellum-dependent cell motility (GO:0001539)7.77734277
4myofibril assembly (GO:0030239)7.73995976
5motile cilium assembly (GO:0044458)7.61351113
6negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.51761456
7skeletal muscle contraction (GO:0003009)7.41749625
8actin-myosin filament sliding (GO:0033275)7.25060838
9muscle filament sliding (GO:0030049)7.25060838
10cardiac muscle contraction (GO:0060048)6.94950479
11negative regulation of potassium ion transmembrane transport (GO:1901380)6.84398965
12cardiac muscle cell development (GO:0055013)6.43771213
13cilium movement (GO:0003341)6.37993223
14regulation of relaxation of muscle (GO:1901077)6.37507832
15regulation of actin filament-based movement (GO:1903115)6.15631798
16cardiac cell development (GO:0055006)6.05863616
17regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.05280299
18cardiac muscle tissue morphogenesis (GO:0055008)6.01905094
19actin-mediated cell contraction (GO:0070252)5.99601943
20actomyosin structure organization (GO:0031032)5.80131755
21ventricular cardiac muscle tissue morphogenesis (GO:0055010)5.77199711
22regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.77142064
23tricarboxylic acid cycle (GO:0006099)5.71517910
24positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.70314374
25cardiac muscle hypertrophy (GO:0003300)5.68791234
26epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)5.66140443
27muscle tissue morphogenesis (GO:0060415)5.48495112
28adult heart development (GO:0007512)5.47130082
29bundle of His cell to Purkinje myocyte communication (GO:0086069)5.44128448
30striated muscle hypertrophy (GO:0014897)5.42736738
31heart trabecula formation (GO:0060347)5.39228516
32regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.32265571
33epithelial cilium movement (GO:0003351)5.30839901
34regulation of sarcomere organization (GO:0060297)5.28296409
35ventricular cardiac muscle cell action potential (GO:0086005)5.22921954
36striated muscle contraction (GO:0006941)5.22192541
37regulation of the force of heart contraction (GO:0002026)5.09711707
38plasma membrane repair (GO:0001778)5.04039063
39heart contraction (GO:0060047)4.94028008
40heart process (GO:0003015)4.94028008
41negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.90841570
42regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)4.89980957
43left/right pattern formation (GO:0060972)4.89584994
44regulation of striated muscle contraction (GO:0006942)4.84594979
45muscle hypertrophy (GO:0014896)4.83554899
46regulation of skeletal muscle contraction (GO:0014819)4.81661155
47regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)4.59044869
48skeletal muscle adaptation (GO:0043501)4.57294590
49actin filament-based movement (GO:0030048)4.55151779
50response to muscle activity (GO:0014850)4.54121920
51regulation of cardiac muscle cell contraction (GO:0086004)4.44396939
52regulation of cell communication by electrical coupling (GO:0010649)4.40017608
53regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.37899053
54regulation of cardioblast differentiation (GO:0051890)4.32431711
55negative regulation of striated muscle cell apoptotic process (GO:0010664)4.32147792
56carnitine shuttle (GO:0006853)4.31608855
57cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.29760030
58cell communication involved in cardiac conduction (GO:0086065)4.15000372
59mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.12927349
60sarcoplasmic reticulum calcium ion transport (GO:0070296)4.12383411
61regulation of acyl-CoA biosynthetic process (GO:0050812)4.11618285
62axoneme assembly (GO:0035082)4.11598583
63regulation of membrane repolarization (GO:0060306)4.09680347
64regulation of cardiac muscle contraction (GO:0055117)4.04782635
65cardiac muscle hypertrophy in response to stress (GO:0014898)4.00542141
66muscle hypertrophy in response to stress (GO:0003299)4.00542141
67cardiac muscle adaptation (GO:0014887)4.00542141
68regulation of ATP catabolic process (GO:1903289)3.99340048
69regulation of ATPase activity (GO:0043462)3.99340048
70ventricular cardiac muscle cell development (GO:0055015)3.98539855
71negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)3.90122412
72energy coupled proton transport, down electrochemical gradient (GO:0015985)3.83617781
73ATP synthesis coupled proton transport (GO:0015986)3.83617781
74negative regulation of potassium ion transport (GO:0043267)3.83048298
75relaxation of cardiac muscle (GO:0055119)3.82745754
76striated muscle atrophy (GO:0014891)3.82581887
77oxidative phosphorylation (GO:0006119)3.79753101
78regulation of cofactor metabolic process (GO:0051193)3.76841115
79regulation of coenzyme metabolic process (GO:0051196)3.76841115
80regulation of heart rate (GO:0002027)3.71702283
81response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.71400469
82fatty acid transmembrane transport (GO:1902001)3.68988945
83primary alcohol catabolic process (GO:0034310)3.67045131
84striated muscle cell development (GO:0055002)3.63053212
85oxygen transport (GO:0015671)3.62325223
86cell communication by electrical coupling (GO:0010644)3.60394150
87regulation of heart contraction (GO:0008016)3.60046976
88regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.56803794
89creatine metabolic process (GO:0006600)3.56552536
90cardiac muscle cell action potential involved in contraction (GO:0086002)3.54385998
91positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.54014648
92cardiac muscle cell action potential (GO:0086001)3.50923941
93respiratory electron transport chain (GO:0022904)3.45254625
94regulation of muscle contraction (GO:0006937)3.39976160
95muscle adaptation (GO:0043500)3.37604900
96muscle contraction (GO:0006936)3.37314866
972-oxoglutarate metabolic process (GO:0006103)3.36821432
98trabecula formation (GO:0060343)3.36407595
99electron transport chain (GO:0022900)3.36090893
100cardiac chamber formation (GO:0003207)3.32489739
101mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.32437939
102negative regulation of protein localization to cell surface (GO:2000009)3.31396124
103ethanol metabolic process (GO:0006067)3.29926386
104regulation of striated muscle cell apoptotic process (GO:0010662)3.27125163
105regulation of germinal center formation (GO:0002634)3.26177741
106atrial septum morphogenesis (GO:0060413)3.25838093
107carnitine transmembrane transport (GO:1902603)3.25710912
108NADH metabolic process (GO:0006734)3.25020092
109skeletal muscle fiber development (GO:0048741)3.24771224
110muscle atrophy (GO:0014889)3.24335239
111cardiac conduction (GO:0061337)3.21949771
112striated muscle adaptation (GO:0014888)3.21890377
113muscle system process (GO:0003012)3.20901343
114positive regulation of heart contraction (GO:0045823)3.20791780
115muscle cell development (GO:0055001)3.17801113
116oxaloacetate metabolic process (GO:0006107)3.14642907
117positive regulation of cation channel activity (GO:2001259)3.10326608
118response to inactivity (GO:0014854)3.09862450
119negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.09035926
120regulation of heart rate by cardiac conduction (GO:0086091)3.08513783
121atrioventricular valve morphogenesis (GO:0003181)3.08154178
122skeletal muscle tissue development (GO:0007519)3.06628959
123vitamin transmembrane transport (GO:0035461)3.05395949
124negative regulation of inclusion body assembly (GO:0090084)2.95750627
125glycogen catabolic process (GO:0005980)2.94275227
126myotube cell development (GO:0014904)2.92589195
127cytoplasmic microtubule organization (GO:0031122)2.92500210
128negative regulation of calcium ion transmembrane transporter activity (GO:1901020)2.92075701
129negative regulation of calcium ion transmembrane transport (GO:1903170)2.92075701
130carnitine transport (GO:0015879)2.89801758
131amino-acid betaine transport (GO:0015838)2.89801758
132regulation of calcium ion transmembrane transport (GO:1903169)2.89226926
133regulation of calcium ion transmembrane transporter activity (GO:1901019)2.89226926
134one-carbon compound transport (GO:0019755)2.86522569
135regulation of cilium movement (GO:0003352)2.82780542
136muscle fiber development (GO:0048747)2.77826638
137negative regulation of necroptotic process (GO:0060546)2.73966496
138sperm capacitation (GO:0048240)2.73614732
139pyrimidine-containing compound transmembrane transport (GO:0072531)2.72910580
140glucan catabolic process (GO:0009251)2.72522447
141muscle cell cellular homeostasis (GO:0046716)2.72367502
142muscle cell fate commitment (GO:0042693)2.70619354
143muscle organ morphogenesis (GO:0048644)2.66046021
144axonemal dynein complex assembly (GO:0070286)10.0615685

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.51185716
2EP300_21415370_ChIP-Seq_HL-1_Mouse4.51845673
3TBX20_22328084_ChIP-Seq_HEART_Mouse3.78864747
4TBX20_22080862_ChIP-Seq_HEART_Mouse3.78864747
5RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.66509625
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.61034192
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse3.48370196
8ESRRB_18555785_ChIP-Seq_MESCs_Mouse3.44671014
9STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.33339665
10MEF2A_21415370_ChIP-Seq_HL-1_Mouse2.96053385
11NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.85676062
12RARG_19884340_ChIP-ChIP_MEFs_Mouse2.75760608
13ZNF263_19887448_ChIP-Seq_K562_Human2.61355687
14CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.60167462
15KDM2B_26808549_Chip-Seq_SUP-B15_Human2.38452320
16* CLOCK_20551151_ChIP-Seq_293T_Human2.32407626
17GATA4_21415370_ChIP-Seq_HL-1_Mouse2.31816217
18TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.31633819
19ESR1_20079471_ChIP-ChIP_T-47D_Human2.29542705
20THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.27450451
21EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.23517556
22TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.09970991
23BP1_19119308_ChIP-ChIP_Hs578T_Human2.03755681
24KDM2B_26808549_Chip-Seq_DND41_Human1.99058076
25ELK3_25401928_ChIP-Seq_HUVEC_Human1.98320898
26PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.88277178
27HIF1A_21447827_ChIP-Seq_MCF-7_Human1.86799512
28PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.78868538
29TRIM28_21343339_ChIP-Seq_HEK293_Human1.76139824
30FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.75853546
31NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.73450324
32TCF7_22412390_ChIP-Seq_EML_Mouse1.73212375
33DROSHA_22980978_ChIP-Seq_HELA_Human1.71763065
34ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.68165507
35FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.68097249
36MYC_22102868_ChIP-Seq_BL_Human1.66014655
37* MAF_26560356_Chip-Seq_TH1_Human1.63977403
38EGR1_19374776_ChIP-ChIP_THP-1_Human1.63875138
39TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.62303560
40KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.61300977
41RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.57491271
42VDR_21846776_ChIP-Seq_THP-1_Human1.53450880
43ESR2_21235772_ChIP-Seq_MCF-7_Human1.52458264
44RUNX_20019798_ChIP-Seq_JUKART_Human1.51754318
45PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.51028549
46SMC4_20622854_ChIP-Seq_HELA_Human1.49028693
47RXR_22158963_ChIP-Seq_LIVER_Mouse1.42669058
48NFIB_24661679_ChIP-Seq_LUNG_Mouse1.42492568
49* CTCF_27219007_Chip-Seq_Bcells_Human1.41011604
50GATA1_19941826_ChIP-Seq_K562_Human1.40274700
51KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.40119023
52GATA2_21666600_ChIP-Seq_HMVEC_Human1.39391089
53RACK7_27058665_Chip-Seq_MCF-7_Human1.38939889
54UTX_26944678_Chip-Seq_JUKART_Human1.36562780
55STAT1_20625510_ChIP-Seq_HELA_Human1.31403037
56* P63_26484246_Chip-Seq_KERATINOCYTES_Human1.30749668
57GATA1_22025678_ChIP-Seq_K562_Human1.29897285
58SPI1_23127762_ChIP-Seq_K562_Human1.29313600
59CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.29131398
60RUNX1_27514584_Chip-Seq_MCF-7_Human1.28062950
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.27423867
62RAD21_21589869_ChIP-Seq_MESCs_Mouse1.27414233
63LXR_22158963_ChIP-Seq_LIVER_Mouse1.27362484
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.26440303
65ATF3_27146783_Chip-Seq_COLON_Human1.25714941
66ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.24991834
67WT1_19549856_ChIP-ChIP_CCG9911_Human1.24185614
68PPARA_22158963_ChIP-Seq_LIVER_Mouse1.23414884
69LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.23035182
70LXR_22292898_ChIP-Seq_THP-1_Human1.22769147
71* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22206121
72FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.22167787
73SOX9_24532713_ChIP-Seq_HFSC_Mouse1.21857057
74CDX2_19796622_ChIP-Seq_MESCs_Mouse1.21246795
75PPAR_26484153_Chip-Seq_NCI-H1993_Human1.20361547
76ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.18425913
77ELF1_20517297_ChIP-Seq_JURKAT_Human1.16526718
78STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15875682
79* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.15295522
80ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.14913469
81NOTCH1_21737748_ChIP-Seq_TLL_Human1.14111326
82SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.12824128
83SOX2_27498859_Chip-Seq_STOMACH_Mouse1.12516376
84NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.11101514
85NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.08377815
86GATA2_19941826_ChIP-Seq_K562_Human1.08269488
87FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.08138856
88RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.07671505
89KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.07625285
90KDM2B_26808549_Chip-Seq_JURKAT_Human1.07264709
91CREB1_26743006_Chip-Seq_LNCaP_Human1.06872856
92SPI1_20517297_ChIP-Seq_HL60_Human1.06143484
93P68_20966046_ChIP-Seq_HELA_Human1.04963462
94ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.04660767
95BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04070176
96E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.03410884
97FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.03259822
98ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.03252385
99STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.02632028
100ISL1_27105846_Chip-Seq_CPCs_Mouse1.02516909
101ERG_21242973_ChIP-ChIP_JURKAT_Human1.01612305
102SA1_27219007_Chip-Seq_ERYTHROID_Human1.01313832
103SCL_19346495_ChIP-Seq_HPC-7_Human1.01231501
104SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.00792828
105GATA1_19941827_ChIP-Seq_MEL_Mouse1.00480184
106DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00247550
107TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.99831597
108NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.99527669
109MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.98782499
110SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.98179126
111IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.97587182
112STAT4_19710469_ChIP-ChIP_TH1__Mouse0.97585454
113EGR1_19032775_ChIP-ChIP_M12_Human0.97030391
114VDR_24763502_ChIP-Seq_THP-1_Human0.96708830
115SMC3_22415368_ChIP-Seq_MEFs_Mouse0.96453656
116IRF8_22096565_ChIP-ChIP_GC-B_Human0.95962687
117SA1_27219007_Chip-Seq_Bcells_Human0.95806179
118MYC_27129775_Chip-Seq_CORNEA_Mouse0.95095125
119GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95060007
120* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.94340999
121Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.94270294
122CTCF_21964334_Chip-Seq_Bcells_Human0.94131936
123SMC1_22415368_ChIP-Seq_MEFs_Mouse0.93434245
124YY1_22570637_ChIP-Seq_MALME-3M_Human0.93211461
125ESR1_21235772_ChIP-Seq_MCF-7_Human0.92784786
126ZFP281_18757296_ChIP-ChIP_E14_Mouse0.92009663
127TP53_23651856_ChIP-Seq_MEFs_Mouse0.91983746
128CJUN_26792858_Chip-Seq_BT549_Human0.91821391
129PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91648464
130KDM2B_26808549_Chip-Seq_K562_Human0.91219231
131TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.91075102
132TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.90137141
133FOXO3_23340844_ChIP-Seq_DLD1_Human0.89331699
134JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89248146
135SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88601356
136CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88224887
137* DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.87986543
138HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.87933017
139* BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.87781766
140CTCF_21964334_ChIP-Seq_BJAB-B_Human0.87777592
141MYB_26560356_Chip-Seq_TH2_Human0.87653183
142* BCOR_27268052_Chip-Seq_Bcells_Human0.86943166
143STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.86896824
144TP63_22573176_ChIP-Seq_HFKS_Human0.86393609
145UBF1/2_26484160_Chip-Seq_HMECs_Human0.86133316
146SRY_22984422_ChIP-ChIP_TESTIS_Rat0.86058882
147EZH2_27294783_Chip-Seq_ESCs_Mouse0.85944109
148SOX2_20726797_ChIP-Seq_SW620_Human0.85823712
149STAT6_21828071_ChIP-Seq_BEAS2B_Human0.85723720
150PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.85350952

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.97787668
2MP0004084_abnormal_cardiac_muscle5.94332987
3MP0000751_myopathy4.78069940
4MP0003646_muscle_fatigue4.71412879
5MP0004215_abnormal_myocardial_fiber4.45629045
6MP0004036_abnormal_muscle_relaxation4.26950385
7MP0005330_cardiomyopathy4.07863035
8MP0000749_muscle_degeneration3.79423885
9* MP0002972_abnormal_cardiac_muscle3.16888474
10MP0008775_abnormal_heart_ventricle3.11882990
11MP0004510_myositis3.09484638
12MP0004087_abnormal_muscle_fiber3.04636010
13MP0003137_abnormal_impulse_conducting2.83878162
14MP0010630_abnormal_cardiac_muscle2.77647546
15MP0001544_abnormal_cardiovascular_syste2.70954734
16MP0005385_cardiovascular_system_phenoty2.70954734
17MP0000750_abnormal_muscle_regeneration2.65891212
18MP0003828_pulmonary_edema2.60789965
19MP0005620_abnormal_muscle_contractility2.59437102
20MP0006138_congestive_heart_failure2.52951917
21MP0002106_abnormal_muscle_physiology2.43115330
22MP0004484_altered_response_of2.40118037
23MP0004130_abnormal_muscle_cell2.14824486
24MP0004085_abnormal_heartbeat2.10041031
25MP0003221_abnormal_cardiomyocyte_apopto2.07246683
26MP0002269_muscular_atrophy2.06716316
27MP0005369_muscle_phenotype1.93077647
28MP0000747_muscle_weakness1.91885084
29MP0004145_abnormal_muscle_electrophysio1.79640831
30MP0000759_abnormal_skeletal_muscle1.76942564
31MP0002127_abnormal_cardiovascular_syste1.72097265
32MP0003279_aneurysm1.66562319
33MP0009780_abnormal_chondrocyte_physiolo1.63414178
34MP0004043_abnormal_pH_regulation1.62656993
35MP0003656_abnormal_erythrocyte_physiolo1.59237259
36MP0008875_abnormal_xenobiotic_pharmacok1.51041464
37MP0003950_abnormal_plasma_membrane1.48882994
38MP0006036_abnormal_mitochondrial_physio1.43595863
39MP0002132_abnormal_respiratory_system1.39828135
40MP0003567_abnormal_fetal_cardiomyocyte1.39298672
41MP0000343_altered_response_to1.36657707
42MP0002653_abnormal_ependyma_morphology1.31591732
43MP0004233_abnormal_muscle_weight1.31521439
44MP0010368_abnormal_lymphatic_system1.25452322
45MP0002332_abnormal_exercise_endurance1.22707949
46* MP0000266_abnormal_heart_morphology1.20327249
47MP0009840_abnormal_foam_cell1.18484898
48MP0005165_increased_susceptibility_to1.17403950
49MP0005666_abnormal_adipose_tissue1.11904538
50MP0008004_abnormal_stomach_pH1.06471300
51MP0003075_altered_response_to1.05294445
52MP0003566_abnormal_cell_adhesion1.03570467
53MP0003453_abnormal_keratinocyte_physiol0.99814177
54MP0002234_abnormal_pharynx_morphology0.98623938
55MP0002128_abnormal_blood_circulation0.97015535
56MP0005623_abnormal_meninges_morphology0.92608396
57MP0003806_abnormal_nucleotide_metabolis0.91397373
58MP0005670_abnormal_white_adipose0.90886571
59MP0005166_decreased_susceptibility_to0.89996825
60MP0005058_abnormal_lysosome_morphology0.88949431
61MP0009384_cardiac_valve_regurgitation0.88853873
62MP0005375_adipose_tissue_phenotype0.87410110
63MP0000733_abnormal_muscle_development0.87009270
64MP0005451_abnormal_body_composition0.86390442
65MP0000767_abnormal_smooth_muscle0.86303512
66MP0000013_abnormal_adipose_tissue0.85275845
67MP0002139_abnormal_hepatobiliary_system0.84098280
68MP0000230_abnormal_systemic_arterial0.83701685
69MP0001879_abnormal_lymphatic_vessel0.82638271
70MP0001853_heart_inflammation0.82183513
71MP0006082_CNS_inflammation0.80167860
72MP0005167_abnormal_blood-brain_barrier0.78502505
73MP0001984_abnormal_olfaction0.73660161
74MP0003191_abnormal_cellular_cholesterol0.73256476
75MP0004185_abnormal_adipocyte_glucose0.73139077
76MP0003122_maternal_imprinting0.72006275
77MP0004272_abnormal_basement_membrane0.71486522
78MP0006035_abnormal_mitochondrial_morpho0.68583410
79MP0002277_abnormal_respiratory_mucosa0.67484248
80MP0005083_abnormal_biliary_tract0.67271472
81MP0002108_abnormal_muscle_morphology0.67062673
82MP0002148_abnormal_hypersensitivity_rea0.65513127
83MP0000003_abnormal_adipose_tissue0.65065847
84MP0000685_abnormal_immune_system0.64319296
85MP0002925_abnormal_cardiovascular_devel0.63126594
86MP0008961_abnormal_basal_metabolism0.62894579
87MP0002168_other_aberrant_phenotype0.61962614
88MP0003705_abnormal_hypodermis_morpholog0.61338760
89MP0003763_abnormal_thymus_physiology0.59013850
90MP0005164_abnormal_response_to0.58193085
91MP0005023_abnormal_wound_healing0.58070699
92MP0002933_joint_inflammation0.57496393
93MP0003303_peritoneal_inflammation0.53570494
94MP0002166_altered_tumor_susceptibility0.53469225
95MP0005266_abnormal_metabolism0.52325050
96MP0001614_abnormal_blood_vessel0.51977831
97MP0002998_abnormal_bone_remodeling0.51417321
98MP0001784_abnormal_fluid_regulation0.51330648
99MP0003879_abnormal_hair_cell0.50144994
100MP0000249_abnormal_blood_vessel0.49448837
101MP0008438_abnormal_cutaneous_collagen0.49272766
102MP0002896_abnormal_bone_mineralization0.49114941
103MP0005376_homeostasis/metabolism_phenot0.48974852
104MP0002909_abnormal_adrenal_gland0.48813506
105MP0002088_abnormal_embryonic_growth/wei0.48709261
106MP0009764_decreased_sensitivity_to0.48576424
107MP0004808_abnormal_hematopoietic_stem0.47948047
108MP0003984_embryonic_growth_retardation0.47685979
109MP0009785_altered_susceptibility_to0.46364533
110MP0001765_abnormal_ion_homeostasis0.45515212
111MP0003436_decreased_susceptibility_to0.45456620
112MP0005584_abnormal_enzyme/coenzyme_acti0.44776359
113MP0000858_altered_metastatic_potential0.43200811
114MP0009278_abnormal_bone_marrow0.43160681
115MP0010155_abnormal_intestine_physiology0.42143404
116MP0009763_increased_sensitivity_to0.41333461
117MP0008874_decreased_physiological_sensi0.40992629
118MP0000678_abnormal_parathyroid_gland0.40710908
119MP0003941_abnormal_skin_development0.39217200
120MP0002971_abnormal_brown_adipose0.38528539
121MP0005319_abnormal_enzyme/_coenzyme0.37091628
122MP0003091_abnormal_cell_migration0.36875632
123MP0003948_abnormal_gas_homeostasis0.34782066
124MP0001727_abnormal_embryo_implantation0.34475246
125MP0005275_abnormal_skin_tensile0.34048296
126MP0003300_gastrointestinal_ulcer0.33952621
127MP0001958_emphysema0.32812043
128MP0001790_abnormal_immune_system0.31705707
129MP0005387_immune_system_phenotype0.31705707
130MP0003724_increased_susceptibility_to0.31489184
131MP0003045_fibrosis0.30710224
132MP0001835_abnormal_antigen_presentation0.30130198
133MP0002877_abnormal_melanocyte_morpholog0.29567536
134MP0005595_abnormal_vascular_smooth0.28173182
135MP0006054_spinal_hemorrhage0.27976739
136MP0002078_abnormal_glucose_homeostasis0.27621244
137MP0002133_abnormal_respiratory_system0.25399006
138MP0005388_respiratory_system_phenotype0.25399006
139MP0001800_abnormal_humoral_immune0.24202806

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)8.17461038
2Respiratory insufficiency due to defective ciliary clearance (HP:0200073)7.14338447
3Ventricular tachycardia (HP:0004756)7.04706045
4Abnormal respiratory motile cilium morphology (HP:0005938)6.45098339
5Abnormal respiratory epithelium morphology (HP:0012253)6.45098339
6Absent/shortened dynein arms (HP:0200106)6.28723676
7Dynein arm defect of respiratory motile cilia (HP:0012255)6.28723676
8Atrial fibrillation (HP:0005110)6.27040156
9Abnormal respiratory motile cilium physiology (HP:0012261)6.22599028
10Abnormal ciliary motility (HP:0012262)6.11204167
11Calf muscle hypertrophy (HP:0008981)6.10339464
12Primary atrial arrhythmia (HP:0001692)5.88587556
13Exercise-induced muscle cramps (HP:0003710)5.83058970
14Rhinitis (HP:0012384)5.78290360
15Supraventricular tachycardia (HP:0004755)5.71845003
16Lipoatrophy (HP:0100578)5.68209313
17Supraventricular arrhythmia (HP:0005115)5.62415607
18Exercise-induced myalgia (HP:0003738)5.54077040
19Muscle fiber splitting (HP:0003555)5.51403622
20Muscle hypertrophy of the lower extremities (HP:0008968)5.43781369
21Abnormality of the left ventricular outflow tract (HP:0011103)5.41619362
22Subaortic stenosis (HP:0001682)5.41619362
23Abnormality of the calf musculature (HP:0001430)5.33412888
24Right ventricular cardiomyopathy (HP:0011663)5.13878389
25Hyporeflexia of lower limbs (HP:0002600)5.02703422
26Syncope (HP:0001279)4.84110816
27Myoglobinuria (HP:0002913)4.64076443
28Dilated cardiomyopathy (HP:0001644)4.60785951
29Palpitations (HP:0001962)4.49222298
30Nasal polyposis (HP:0100582)4.46362559
31Bundle branch block (HP:0011710)4.31913135
32Prolonged QT interval (HP:0001657)4.24273790
33Ventricular arrhythmia (HP:0004308)4.23994469
34Chronic bronchitis (HP:0004469)4.22425073
35EMG: myopathic abnormalities (HP:0003458)4.20980034
36Bronchiectasis (HP:0002110)4.06227397
37Abnormality of the nasal mucosa (HP:0000433)3.98441416
38Asymmetric septal hypertrophy (HP:0001670)3.96436682
39Myopathic facies (HP:0002058)3.76876447
40Atrioventricular block (HP:0001678)3.74176323
41Heart block (HP:0012722)3.69684705
42Rhabdomyolysis (HP:0003201)3.66623574
43Ventricular fibrillation (HP:0001663)3.64922210
44Increased connective tissue (HP:0009025)3.64461500
45Abnormal atrioventricular conduction (HP:0005150)3.52634780
46Distal arthrogryposis (HP:0005684)3.15713691
47Abnormal EKG (HP:0003115)3.13368576
48Myotonia (HP:0002486)3.08475612
49Left ventricular hypertrophy (HP:0001712)3.07286346
50Difficulty running (HP:0009046)3.02088660
51Type 1 muscle fiber predominance (HP:0003803)2.98162607
52Ulnar deviation of the wrist (HP:0003049)2.96047432
53Round ear (HP:0100830)2.90838105
54Distal lower limb muscle weakness (HP:0009053)2.80736029
55Difficulty climbing stairs (HP:0003551)2.73556582
56Palmoplantar keratoderma (HP:0000982)2.66337109
57Hepatic necrosis (HP:0002605)2.65537407
58Ragged-red muscle fibers (HP:0003200)2.64474117
59Abnormal mitochondria in muscle tissue (HP:0008316)2.54758203
60Limb-girdle muscle atrophy (HP:0003797)2.52330901
61Increased variability in muscle fiber diameter (HP:0003557)2.51142747
62Neck muscle weakness (HP:0000467)2.51106215
63Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.50295862
64Infertility (HP:0000789)2.46214416
65Male infertility (HP:0003251)2.44988444
66Areflexia of lower limbs (HP:0002522)2.44295613
67Acute necrotizing encephalopathy (HP:0006965)2.42465658
68Recurrent sinusitis (HP:0011108)2.41760209
69Muscle fiber inclusion bodies (HP:0100299)2.39699798
70Hepatocellular necrosis (HP:0001404)2.36808243
71Sudden cardiac death (HP:0001645)2.35938239
72Conjunctival hamartoma (HP:0100780)2.34029046
73Abnormality of skeletal muscle fiber size (HP:0012084)2.33213913
74Hyperkalemia (HP:0002153)2.29762324
75Bulbar palsy (HP:0001283)2.28948533
76Bronchitis (HP:0012387)2.23484764
77Frequent falls (HP:0002359)2.23054497
78Increased muscle lipid content (HP:0009058)2.22127000
79Mildly elevated creatine phosphokinase (HP:0008180)2.21529283
80Double outlet right ventricle (HP:0001719)2.21179352
81Congenital malformation of the right heart (HP:0011723)2.21179352
82Ketoacidosis (HP:0001993)2.20004661
83Abnormality of the foot musculature (HP:0001436)2.17129007
84Muscle stiffness (HP:0003552)2.16367233
85Broad metatarsal (HP:0001783)2.15101811
86Generalized muscle weakness (HP:0003324)2.14934432
87Fetal akinesia sequence (HP:0001989)2.14634457
88Centrally nucleated skeletal muscle fibers (HP:0003687)2.13227183
89Recurrent otitis media (HP:0000403)2.13020927
90Testicular atrophy (HP:0000029)2.12989296
91Atelectasis (HP:0100750)2.12385355
92Congestive heart failure (HP:0001635)2.11191373
93Mitochondrial inheritance (HP:0001427)2.09468819
94Chronic sinusitis (HP:0011109)2.08052162
95Acute encephalopathy (HP:0006846)2.02118778
96Increased CSF lactate (HP:0002490)2.01404978
97Scapular winging (HP:0003691)2.00990600
98Exercise intolerance (HP:0003546)1.99528390
99Distal lower limb amyotrophy (HP:0008944)1.97802381
100Cerebral aneurysm (HP:0004944)1.97147633
101Abnormality of fatty-acid metabolism (HP:0004359)1.97034327
102Gowers sign (HP:0003391)1.97009866
103Foot dorsiflexor weakness (HP:0009027)1.96925860
104Esophageal neoplasm (HP:0100751)1.96623098
105Neoplasm of head and neck (HP:0012288)1.96623098
106Diaphragmatic weakness (HP:0009113)1.96506050
107Progressive macrocephaly (HP:0004481)1.96477623
108Rimmed vacuoles (HP:0003805)1.95085381
109Hypoglycemic coma (HP:0001325)1.94472533
110Facial diplegia (HP:0001349)1.93114079
111Pheochromocytoma (HP:0002666)1.92021989
112Malignant hyperthermia (HP:0002047)1.91880706
113Increased intramyocellular lipid droplets (HP:0012240)1.90073815
114Dicarboxylic aciduria (HP:0003215)1.89860245
115Abnormality of dicarboxylic acid metabolism (HP:0010995)1.89860245
116Pulmonary artery stenosis (HP:0004415)1.89198643
117Proximal amyotrophy (HP:0007126)1.88254978
118EMG: neuropathic changes (HP:0003445)1.88229237
119Nemaline bodies (HP:0003798)1.87847979
120Lactic acidosis (HP:0003128)1.84412796
121Neoplasm of the adrenal gland (HP:0100631)1.83502806
122Calcaneovalgus deformity (HP:0001848)1.82753677
123Popliteal pterygium (HP:0009756)1.82747110
124Hip contracture (HP:0003273)1.82149388
125Hypoplastic left heart (HP:0004383)1.80459191
126Aplasia of the musculature (HP:0100854)1.79011028
127Respiratory failure (HP:0002878)1.78312526
128Cerebral edema (HP:0002181)1.77995334
129Muscular dystrophy (HP:0003560)1.77849061
130Hyperactive renin-angiotensin system (HP:0000841)1.74077090
131Neuroendocrine neoplasm (HP:0100634)1.73033391
132Dysmetric saccades (HP:0000641)1.71743119
133Lower limb amyotrophy (HP:0007210)1.69627261
134Progressive muscle weakness (HP:0003323)1.68947280
135Spinal rigidity (HP:0003306)1.68838939
136Abnormality of the endocardium (HP:0004306)1.68422010
137Absent phalangeal crease (HP:0006109)1.68368399
138Waddling gait (HP:0002515)1.68060855
139Hyperalaninemia (HP:0003348)1.67952733
140Abnormality of the shoulder girdle musculature (HP:0001435)1.62831392
141Bell-shaped thorax (HP:0001591)1.59893364
142Deformed tarsal bones (HP:0008119)1.58824856

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN5.22408085
2MYLK5.08463521
3MAPK154.76833914
4OBSCN4.62590933
5PKN23.65846727
6DMPK3.35232005
7TRIB33.07455596
8LMTK22.97572129
9PHKG12.82597425
10PHKG22.82597425
11PDK42.47669402
12PDK32.47669402
13STK242.46492145
14MUSK2.16931731
15PIK3CA2.10007156
16EPHA22.04813598
17TIE12.02890657
18GRK71.98099198
19BCKDK1.76198408
20TAOK21.68525887
21PIK3CG1.50024523
22ILK1.45264686
23TAOK11.42158673
24MAP4K11.35893973
25MST41.35198416
26IRAK31.33162814
27PDK21.30830351
28MOS1.29818737
29PAK31.29633672
30FLT31.29248125
31ZAK1.22370650
32TGFBR21.21290645
33PRKD11.19587036
34CDC42BPA1.14684205
35NEK11.12790367
36NME11.12376402
37DAPK31.10949739
38MAP3K71.08738451
39EPHB11.08516159
40CAMK2D1.07754588
41PINK11.06609132
42KDR1.05320343
43MAP2K31.04957965
44ROCK11.01924319
45ICK0.98562715
46TBK10.98246057
47TYK20.94210486
48MAPKAPK30.93743103
49TESK10.92068877
50RIPK10.90379112
51JAK10.89237207
52PIM20.86890125
53MAPK120.86496029
54MAP2K60.86243012
55MAP3K100.84322935
56STK40.82318328
57FGFR40.82099305
58DDR20.80718698
59MAP3K50.80663020
60MAP3K30.79807760
61TRPM70.76200353
62DYRK1B0.76020383
63STK38L0.75713897
64PDGFRA0.75123215
65PKN10.74836806
66EPHA30.72076825
67MAP3K10.71313875
68CSK0.71183291
69ITK0.70755535
70PRKAA20.69744318
71LATS20.69400599
72LRRK20.68220633
73PTK60.67349453
74MARK20.66821519
75ZAP700.64756503
76CAMK40.64516313
77PTK2B0.64463263
78RPS6KL10.64438499
79RPS6KC10.64438499
80PRPF4B0.62954823
81RPS6KA60.62887962
82CAMK10.62375576
83NME20.60426156
84ABL20.60080505
85SMG10.59668573
86ARAF0.59532857
87PAK20.59343122
88MAP3K60.58844653
89ROCK20.56954528
90NEK90.56465697
91JAK30.55515200
92WNK40.55204080
93MAPK40.54300514
94MAPK70.54065024
95* CAMK2G0.53665466
96KIT0.52486496
97PRKAA10.50429662
98MAP3K130.48770623
99RPS6KA10.46037591
100MAP3K20.46037342
101TXK0.45214093
102STK100.42582531
103LIMK10.41912878
104EEF2K0.39259807
105RPS6KA20.39149662
106TGFBR10.39066533
107MAP2K40.38307289
108MST1R0.38204626
109MAP3K110.37995085
110FGFR30.36545958
111PRKCH0.36263625
112MAP3K140.36254342
113JAK20.36103559
114MAP2K10.34926156
115IKBKB0.33358186
116NLK0.32725909
117PRKACB0.31892584
118MAPKAPK20.30592877
119PDK10.30151418
120PRKG10.29762060
121IKBKE0.29290472
122MARK30.28548737
123PRKACG0.26355500
124CHUK0.25708950
125PRKG20.25399085
126* PRKACA0.25241904
127RET0.25048900
128CAMK2B0.24967720
129* CAMK2A0.24965513
130PDGFRB0.24938411
131ERBB30.24875860
132RPS6KA50.24821201
133STK380.24442644
134AKT20.23943457
135ERN10.23939875
136PRKCQ0.23400082
137MAPK110.23282500
138SIK10.22184781
139BTK0.21364966
140CCNB10.21136464
141PDPK10.21018402
142BLK0.20412602
143KSR20.20187091
144RPS6KB20.20030512

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.57213973
2Cardiac muscle contraction_Homo sapiens_hsa042604.46814780
3Dilated cardiomyopathy_Homo sapiens_hsa054144.17676777
4Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054104.01099020
52-Oxocarboxylic acid metabolism_Homo sapiens_hsa012103.69258548
6Parkinsons disease_Homo sapiens_hsa050123.13581912
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.03996601
8Oxidative phosphorylation_Homo sapiens_hsa001902.87822187
9Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.61201356
10Propanoate metabolism_Homo sapiens_hsa006402.47746486
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.23678305
12Viral myocarditis_Homo sapiens_hsa054162.22513204
13Alzheimers disease_Homo sapiens_hsa050102.20763825
14Fatty acid degradation_Homo sapiens_hsa000712.19359018
15Carbon metabolism_Homo sapiens_hsa012002.10324646
16Huntingtons disease_Homo sapiens_hsa050161.85354796
17Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.85234850
18Histidine metabolism_Homo sapiens_hsa003401.84797329
19Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.78340154
20Tyrosine metabolism_Homo sapiens_hsa003501.72566691
21Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56819176
22Fatty acid metabolism_Homo sapiens_hsa012121.48004393
23beta-Alanine metabolism_Homo sapiens_hsa004101.34824206
24Pyruvate metabolism_Homo sapiens_hsa006201.30282975
25Chemical carcinogenesis_Homo sapiens_hsa052041.23921456
26Adipocytokine signaling pathway_Homo sapiens_hsa049201.22564644
27cGMP-PKG signaling pathway_Homo sapiens_hsa040221.22488221
28Insulin resistance_Homo sapiens_hsa049311.20005397
29Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.16336199
30Pentose phosphate pathway_Homo sapiens_hsa000301.14968068
31Focal adhesion_Homo sapiens_hsa045101.11110421
32Glutathione metabolism_Homo sapiens_hsa004801.10763670
33Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.10328399
34HIF-1 signaling pathway_Homo sapiens_hsa040661.09905300
35Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.07854227
36Other glycan degradation_Homo sapiens_hsa005111.06353521
37Arginine biosynthesis_Homo sapiens_hsa002200.99149432
38Glucagon signaling pathway_Homo sapiens_hsa049220.92028438
39Insulin signaling pathway_Homo sapiens_hsa049100.89719702
40Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.87489678
41Osteoclast differentiation_Homo sapiens_hsa043800.85968042
42Vascular smooth muscle contraction_Homo sapiens_hsa042700.85847009
43Prion diseases_Homo sapiens_hsa050200.84921279
44Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.82808003
45Starch and sucrose metabolism_Homo sapiens_hsa005000.82471163
46Leukocyte transendothelial migration_Homo sapiens_hsa046700.81176634
47Pertussis_Homo sapiens_hsa051330.80860934
48Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80203492
49Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.78523364
50Biosynthesis of amino acids_Homo sapiens_hsa012300.76507624
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.76231288
52Lysosome_Homo sapiens_hsa041420.74927285
53Toxoplasmosis_Homo sapiens_hsa051450.74824693
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.72577104
55Oxytocin signaling pathway_Homo sapiens_hsa049210.72361455
56Rheumatoid arthritis_Homo sapiens_hsa053230.71946295
57Galactose metabolism_Homo sapiens_hsa000520.71410973
58ECM-receptor interaction_Homo sapiens_hsa045120.68561752
59Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.68483883
60GnRH signaling pathway_Homo sapiens_hsa049120.64826988
61Fatty acid elongation_Homo sapiens_hsa000620.63918499
62Thyroid hormone signaling pathway_Homo sapiens_hsa049190.61832188
63Primary immunodeficiency_Homo sapiens_hsa053400.60998825
64Type II diabetes mellitus_Homo sapiens_hsa049300.58540893
65Platelet activation_Homo sapiens_hsa046110.58246430
66Calcium signaling pathway_Homo sapiens_hsa040200.58104955
67AMPK signaling pathway_Homo sapiens_hsa041520.57898790
68Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.57167739
69AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.57096670
70cAMP signaling pathway_Homo sapiens_hsa040240.56222004
71PPAR signaling pathway_Homo sapiens_hsa033200.56015272
72Amoebiasis_Homo sapiens_hsa051460.55657065
73Renin secretion_Homo sapiens_hsa049240.55476909
74Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54744541
75Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.53767088
76Acute myeloid leukemia_Homo sapiens_hsa052210.53602017
77RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.53487373
78Sphingolipid metabolism_Homo sapiens_hsa006000.53409337
79Leishmaniasis_Homo sapiens_hsa051400.52918803
80Adherens junction_Homo sapiens_hsa045200.51729896
81Salivary secretion_Homo sapiens_hsa049700.50705055
82Complement and coagulation cascades_Homo sapiens_hsa046100.50460969
83Lysine degradation_Homo sapiens_hsa003100.49252505
84Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48572285
85Butanoate metabolism_Homo sapiens_hsa006500.48552241
86Tight junction_Homo sapiens_hsa045300.48295054
87B cell receptor signaling pathway_Homo sapiens_hsa046620.47869245
88Hepatitis C_Homo sapiens_hsa051600.47623477
89Bladder cancer_Homo sapiens_hsa052190.46317487
90Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.45908717
91NF-kappa B signaling pathway_Homo sapiens_hsa040640.44654782
92Small cell lung cancer_Homo sapiens_hsa052220.44484243
93T cell receptor signaling pathway_Homo sapiens_hsa046600.43846985
94Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43625993
95Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.43227116
96Proteoglycans in cancer_Homo sapiens_hsa052050.43163871
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.41279220
98VEGF signaling pathway_Homo sapiens_hsa043700.40597439
99Jak-STAT signaling pathway_Homo sapiens_hsa046300.39837485
100Glycosaminoglycan degradation_Homo sapiens_hsa005310.39240586
101Renal cell carcinoma_Homo sapiens_hsa052110.38844982
102NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38746331
103Measles_Homo sapiens_hsa051620.37859538
104Intestinal immune network for IgA production_Homo sapiens_hsa046720.37853981
105MAPK signaling pathway_Homo sapiens_hsa040100.37133875
106Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.37105387
107Staphylococcus aureus infection_Homo sapiens_hsa051500.35798760
108Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.35036059
109Tuberculosis_Homo sapiens_hsa051520.34774870
110Peroxisome_Homo sapiens_hsa041460.34547092
111Notch signaling pathway_Homo sapiens_hsa043300.34268414
112Legionellosis_Homo sapiens_hsa051340.34039092
113Graft-versus-host disease_Homo sapiens_hsa053320.31842845
114Gastric acid secretion_Homo sapiens_hsa049710.31389052
115Circadian rhythm_Homo sapiens_hsa047100.31265537
116Aldosterone synthesis and secretion_Homo sapiens_hsa049250.31088575
117ABC transporters_Homo sapiens_hsa020100.30515280
118Ovarian steroidogenesis_Homo sapiens_hsa049130.30268691
119HTLV-I infection_Homo sapiens_hsa051660.30063520
120TNF signaling pathway_Homo sapiens_hsa046680.29655413
121Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.29364756
122Antigen processing and presentation_Homo sapiens_hsa046120.27031080
123Chronic myeloid leukemia_Homo sapiens_hsa052200.25243893
124FoxO signaling pathway_Homo sapiens_hsa040680.24497667
125Dorso-ventral axis formation_Homo sapiens_hsa043200.23040235
126Salmonella infection_Homo sapiens_hsa051320.21327745
127Phenylalanine metabolism_Homo sapiens_hsa003600.21239372
128Apoptosis_Homo sapiens_hsa042100.19888379
129Prolactin signaling pathway_Homo sapiens_hsa049170.19128518
130Arginine and proline metabolism_Homo sapiens_hsa003300.18071271
131Malaria_Homo sapiens_hsa051440.18041274
132Fructose and mannose metabolism_Homo sapiens_hsa000510.17979075
133PI3K-Akt signaling pathway_Homo sapiens_hsa041510.17664704
134Neurotrophin signaling pathway_Homo sapiens_hsa047220.17425276
135Estrogen signaling pathway_Homo sapiens_hsa049150.16784357
136Pathways in cancer_Homo sapiens_hsa052000.15798233
137Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.15078296
138Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.14730168
139mTOR signaling pathway_Homo sapiens_hsa041500.14542545

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