RRN3P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)4.31682719
2activated T cell proliferation (GO:0050798)3.73614900
3negative T cell selection (GO:0043383)3.64451146
4neural tube formation (GO:0001841)3.58115090
5negative thymic T cell selection (GO:0045060)3.45436060
6response to pheromone (GO:0019236)3.44004441
7interferon-gamma production (GO:0032609)3.42619317
8regulation of B cell receptor signaling pathway (GO:0050855)3.37242373
9behavioral response to nicotine (GO:0035095)3.32866128
10indolalkylamine metabolic process (GO:0006586)3.31360587
11positive regulation of granulocyte differentiation (GO:0030854)3.24081786
12DNA double-strand break processing (GO:0000729)3.22164193
13tryptophan catabolic process (GO:0006569)3.21846270
14indole-containing compound catabolic process (GO:0042436)3.21846270
15indolalkylamine catabolic process (GO:0046218)3.21846270
16epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.18995111
17L-fucose catabolic process (GO:0042355)3.17778683
18fucose catabolic process (GO:0019317)3.17778683
19L-fucose metabolic process (GO:0042354)3.17778683
20cellular response to interleukin-15 (GO:0071350)3.16421125
21rRNA catabolic process (GO:0016075)3.12817617
22positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.09185539
23positive T cell selection (GO:0043368)3.08678136
24positive regulation of gamma-delta T cell activation (GO:0046645)3.06885540
25preassembly of GPI anchor in ER membrane (GO:0016254)2.98030409
26protein K11-linked deubiquitination (GO:0035871)2.93824201
27tryptophan metabolic process (GO:0006568)2.91220393
28mast cell activation (GO:0045576)2.82288530
29mast cell activation involved in immune response (GO:0002279)2.80008185
30mast cell degranulation (GO:0043303)2.80008185
31detection of light stimulus involved in sensory perception (GO:0050962)2.74094698
32detection of light stimulus involved in visual perception (GO:0050908)2.74094698
33protein complex biogenesis (GO:0070271)2.74021782
34axoneme assembly (GO:0035082)2.73690111
35epithelial cilium movement (GO:0003351)2.73661154
36negative regulation of translation, ncRNA-mediated (GO:0040033)2.70064139
37regulation of translation, ncRNA-mediated (GO:0045974)2.70064139
38negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.70064139
39regulation of gamma-delta T cell differentiation (GO:0045586)2.65137916
40RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.63407274
41detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.62950853
42mitochondrial respiratory chain complex I assembly (GO:0032981)2.62210079
43NADH dehydrogenase complex assembly (GO:0010257)2.62210079
44mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.62210079
45piRNA metabolic process (GO:0034587)2.62160649
46cytochrome complex assembly (GO:0017004)2.60933356
47positive regulation of defense response to virus by host (GO:0002230)2.60524355
48nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.60405329
49response to interleukin-15 (GO:0070672)2.60319994
50regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.59648027
51histone H3-K9 methylation (GO:0051567)2.59214158
52respiratory chain complex IV assembly (GO:0008535)2.58234664
53negative regulation of telomere maintenance (GO:0032205)2.57779727
54kynurenine metabolic process (GO:0070189)2.56277065
55establishment of protein localization to Golgi (GO:0072600)2.54692223
56positive regulation of fatty acid transport (GO:2000193)2.54577965
57regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.54021855
58cytidine deamination (GO:0009972)2.53846306
59cytidine metabolic process (GO:0046087)2.53846306
60cytidine catabolic process (GO:0006216)2.53846306
61regulation of B cell differentiation (GO:0045577)2.52756446
62exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.49751916
63positive regulation of calcium-mediated signaling (GO:0050850)2.49372771
64regulation of telomere maintenance (GO:0032204)2.47672261
65regulation of alpha-beta T cell proliferation (GO:0046640)2.46856242
66alpha-beta T cell differentiation (GO:0046632)2.46454967
67positive thymic T cell selection (GO:0045059)2.46054262
68positive regulation of alpha-beta T cell proliferation (GO:0046641)2.45545004
69protein localization to cilium (GO:0061512)2.45371705
70L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.45086332
71double-strand break repair via homologous recombination (GO:0000724)2.44223124
72recombinational repair (GO:0000725)2.43463672
73negative regulation of interleukin-1 beta production (GO:0032691)2.43161739
74positive regulation of B cell differentiation (GO:0045579)2.42950576
75mitochondrial respiratory chain complex assembly (GO:0033108)2.42634987
76mannosylation (GO:0097502)2.42508513
77T cell selection (GO:0045058)2.42494267
78regulation of gamma-delta T cell activation (GO:0046643)2.41490073
79protein polyglutamylation (GO:0018095)2.41003028
80ubiquinone biosynthetic process (GO:0006744)2.40278721
81positive regulation of prostaglandin secretion (GO:0032308)2.40111416
82platelet dense granule organization (GO:0060155)2.38929156
83regulation of regulatory T cell differentiation (GO:0045589)2.38866045
84cilium or flagellum-dependent cell motility (GO:0001539)2.38519523
85DNA demethylation (GO:0080111)2.37513905
86purinergic nucleotide receptor signaling pathway (GO:0035590)2.37340940
87pyrimidine ribonucleoside catabolic process (GO:0046133)2.37028705
88S-adenosylmethionine metabolic process (GO:0046500)2.36095884
89regulation of T cell receptor signaling pathway (GO:0050856)2.34951965
90replication fork processing (GO:0031297)2.34193724
91negative regulation of mast cell activation (GO:0033004)2.33551782
92adenosine metabolic process (GO:0046085)2.33123532
93positive regulation of mRNA catabolic process (GO:0061014)2.30391851
94indole-containing compound metabolic process (GO:0042430)2.30010718
95ubiquinone metabolic process (GO:0006743)2.29791898
96seminiferous tubule development (GO:0072520)2.29568453
97positive regulation of icosanoid secretion (GO:0032305)2.29520353
98alpha-beta T cell activation (GO:0046631)2.29031136
99regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.28523896
100regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.28025229

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ZNF274_21170338_ChIP-Seq_K562_Hela3.50579703
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.03095194
3IGF1R_20145208_ChIP-Seq_DFB_Human2.93971654
4VDR_22108803_ChIP-Seq_LS180_Human2.84066914
5STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.61823660
6POU3F2_20337985_ChIP-ChIP_501MEL_Human2.41848785
7GBX2_23144817_ChIP-Seq_PC3_Human2.32861166
8ZFP57_27257070_Chip-Seq_ESCs_Mouse2.31773946
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.23572206
10FLI1_27457419_Chip-Seq_LIVER_Mouse2.22542659
11FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.21278047
12TAF15_26573619_Chip-Seq_HEK293_Human2.18230744
13EWS_26573619_Chip-Seq_HEK293_Human2.15405455
14E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.15021276
15FUS_26573619_Chip-Seq_HEK293_Human2.12152102
16HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.00993012
17MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.91029656
18CTBP2_25329375_ChIP-Seq_LNCAP_Human1.86727504
19GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.81907976
20CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.81758221
21GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.81718463
22ER_23166858_ChIP-Seq_MCF-7_Human1.79119946
23VDR_23849224_ChIP-Seq_CD4+_Human1.78023031
24GABP_17652178_ChIP-ChIP_JURKAT_Human1.77914989
25CTBP1_25329375_ChIP-Seq_LNCAP_Human1.77145929
26P300_19829295_ChIP-Seq_ESCs_Human1.76868241
27HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.73070167
28PCGF2_27294783_Chip-Seq_ESCs_Mouse1.67680979
29IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.67282912
30EST1_17652178_ChIP-ChIP_JURKAT_Human1.65924704
31IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.56387582
32GATA3_26560356_Chip-Seq_TH2_Human1.55812712
33IRF1_19129219_ChIP-ChIP_H3396_Human1.54430404
34UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.53833525
35IRF8_21731497_ChIP-ChIP_J774_Mouse1.53820666
36EZH2_22144423_ChIP-Seq_EOC_Human1.52678098
37RUNX_20019798_ChIP-Seq_JUKART_Human1.51124787
38IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.50182666
39CBP_20019798_ChIP-Seq_JUKART_Human1.50182666
40ELF1_17652178_ChIP-ChIP_JURKAT_Human1.49772461
41SALL1_21062744_ChIP-ChIP_HESCs_Human1.49094262
42RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.48253803
43EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.46643161
44AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.45051083
45BCAT_22108803_ChIP-Seq_LS180_Human1.44188486
46TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.42647948
47ELK1_19687146_ChIP-ChIP_HELA_Human1.42457416
48TP53_22573176_ChIP-Seq_HFKS_Human1.41756274
49MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.41681344
50POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.38543770
51TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.38543770
52KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.36401498
53MYB_26560356_Chip-Seq_TH2_Human1.35963889
54PCGF2_27294783_Chip-Seq_NPCs_Mouse1.35017816
55EZH2_27294783_Chip-Seq_NPCs_Mouse1.34279731
56FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.33601476
57STAT3_23295773_ChIP-Seq_U87_Human1.30963922
58SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.29196105
59MYC_18940864_ChIP-ChIP_HL60_Human1.28853170
60SUZ12_27294783_Chip-Seq_NPCs_Mouse1.27063916
61NFE2_27457419_Chip-Seq_LIVER_Mouse1.26294386
62GATA3_27048872_Chip-Seq_THYMUS_Human1.25523701
63FOXP3_21729870_ChIP-Seq_TREG_Human1.23829478
64TCF4_23295773_ChIP-Seq_U87_Human1.23021983
65LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.22673972
66MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.21617081
67PRDM14_20953172_ChIP-Seq_ESCs_Human1.21536216
68CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.21530095
69FOXA1_21572438_ChIP-Seq_LNCaP_Human1.21082710
70AR_25329375_ChIP-Seq_VCAP_Human1.20794598
71SMAD4_21799915_ChIP-Seq_A2780_Human1.20622608
72BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.17641036
73PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.17510938
74FLI1_21867929_ChIP-Seq_TH2_Mouse1.16915006
75TCF4_22108803_ChIP-Seq_LS180_Human1.15033658
76CRX_20693478_ChIP-Seq_RETINA_Mouse1.14040084
77NANOG_19829295_ChIP-Seq_ESCs_Human1.13723864
78SOX2_19829295_ChIP-Seq_ESCs_Human1.13723864
79FOXA1_27270436_Chip-Seq_PROSTATE_Human1.11518521
80FOXA1_25329375_ChIP-Seq_VCAP_Human1.11518521
81GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11030133
82RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.10751181
83NR3C1_21868756_ChIP-Seq_MCF10A_Human1.08527023
84BP1_19119308_ChIP-ChIP_Hs578T_Human1.08339173
85KLF5_20875108_ChIP-Seq_MESCs_Mouse1.07492734
86EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.06922090
87AR_20517297_ChIP-Seq_VCAP_Human1.03466568
88RUNX2_22187159_ChIP-Seq_PCA_Human1.02770062
89NCOR_22424771_ChIP-Seq_293T_Human1.01122256
90OCT4_21477851_ChIP-Seq_ESCs_Mouse1.00742210
91SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00663194
92GATA3_21878914_ChIP-Seq_MCF-7_Human1.00478283
93SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.99224039
94TOP2B_26459242_ChIP-Seq_MCF-7_Human0.98670461
95CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.98309335
96OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98218040
97SMAD3_21741376_ChIP-Seq_EPCs_Human0.96978364
98NANOG_18555785_Chip-Seq_ESCs_Mouse0.96971390
99P53_22387025_ChIP-Seq_ESCs_Mouse0.96559286
100PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.96296020

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008877_abnormal_DNA_methylation2.97667819
2MP0005671_abnormal_response_to2.86733205
3MP0003787_abnormal_imprinting2.82354567
4MP0001986_abnormal_taste_sensitivity2.79689918
5MP0000569_abnormal_digit_pigmentation2.76945163
6MP0002102_abnormal_ear_morphology2.56799933
7MP0001835_abnormal_antigen_presentation2.22578485
8MP0006072_abnormal_retinal_apoptosis2.04218444
9MP0003763_abnormal_thymus_physiology2.03934705
10MP0001800_abnormal_humoral_immune2.02975658
11MP0003724_increased_susceptibility_to1.83899777
12MP0005075_abnormal_melanosome_morpholog1.80892076
13MP0005551_abnormal_eye_electrophysiolog1.74722363
14MP0006292_abnormal_olfactory_placode1.72816616
15MP0001501_abnormal_sleep_pattern1.72812093
16MP0002638_abnormal_pupillary_reflex1.66218973
17MP0008995_early_reproductive_senescence1.66218066
18MP0009785_altered_susceptibility_to1.65660175
19MP0001968_abnormal_touch/_nociception1.63583387
20MP0003880_abnormal_central_pattern1.63431783
21MP0002723_abnormal_immune_serum1.61605641
22MP0003195_calcinosis1.61528964
23MP0000372_irregular_coat_pigmentation1.59943799
24MP0005000_abnormal_immune_tolerance1.58130112
25MP0005253_abnormal_eye_physiology1.57726340
26MP0003646_muscle_fatigue1.52886902
27MP0000685_abnormal_immune_system1.50185605
28MP0009764_decreased_sensitivity_to1.49115571
29MP0002420_abnormal_adaptive_immunity1.48524150
30MP0002148_abnormal_hypersensitivity_rea1.46908720
31MP0001819_abnormal_immune_cell1.44927205
32MP0002452_abnormal_antigen_presenting1.43485955
33MP0002009_preneoplasia1.34655309
34MP0005387_immune_system_phenotype1.34270951
35MP0001790_abnormal_immune_system1.34270951
36MP0005645_abnormal_hypothalamus_physiol1.33964957
37MP0002653_abnormal_ependyma_morphology1.33874382
38MP0005174_abnormal_tail_pigmentation1.32435432
39MP0002876_abnormal_thyroid_physiology1.31826377
40MP0008872_abnormal_physiological_respon1.31561566
41MP0005646_abnormal_pituitary_gland1.30816270
42MP0001984_abnormal_olfaction1.30725213
43MP0004142_abnormal_muscle_tone1.29227972
44MP0001919_abnormal_reproductive_system1.28641441
45MP0004885_abnormal_endolymph1.28254486
46MP0009745_abnormal_behavioral_response1.27965234
47MP0002138_abnormal_hepatobiliary_system1.27319345
48MP0009046_muscle_twitch1.25862975
49MP0006276_abnormal_autonomic_nervous1.25676971
50MP0008875_abnormal_xenobiotic_pharmacok1.23841122
51MP0002928_abnormal_bile_duct1.22416702
52MP0004147_increased_porphyrin_level1.21485170
53MP0000689_abnormal_spleen_morphology1.20960514
54MP0002398_abnormal_bone_marrow1.19230744
55MP0000716_abnormal_immune_system1.19078772
56MP0008058_abnormal_DNA_repair1.16058482
57MP0005389_reproductive_system_phenotype1.15726895
58MP0000427_abnormal_hair_cycle1.13991405
59MP0002405_respiratory_system_inflammati1.13702078
60MP0005310_abnormal_salivary_gland1.10962834
61MP0005025_abnormal_response_to1.09517151
62MP0002272_abnormal_nervous_system1.09412705
63MP0002736_abnormal_nociception_after1.09134825
64MP0000703_abnormal_thymus_morphology1.06098140
65MP0008057_abnormal_DNA_replication1.06012111
66MP0002163_abnormal_gland_morphology1.05993365
67MP0001486_abnormal_startle_reflex1.03030887
68MP0005167_abnormal_blood-brain_barrier1.00654518
69MP0000631_abnormal_neuroendocrine_gland1.00393816
70MP0005084_abnormal_gallbladder_morpholo1.00225940
71MP0004043_abnormal_pH_regulation0.99736000
72MP0002419_abnormal_innate_immunity0.98410362
73MP0010386_abnormal_urinary_bladder0.98048116
74MP0003436_decreased_susceptibility_to0.97073069
75MP0003866_abnormal_defecation0.96618698
76MP0002722_abnormal_immune_system0.95719980
77MP0003121_genomic_imprinting0.95539535
78MP0002166_altered_tumor_susceptibility0.95495189
79MP0004742_abnormal_vestibular_system0.94691608
80MP0004924_abnormal_behavior0.93395137
81MP0005386_behavior/neurological_phenoty0.93395137
82MP0003786_premature_aging0.90836913
83MP0001485_abnormal_pinna_reflex0.89411544
84MP0002277_abnormal_respiratory_mucosa0.88044993
85MP0000015_abnormal_ear_pigmentation0.87800926
86MP0001188_hyperpigmentation0.87693828
87MP0001764_abnormal_homeostasis0.87605070
88MP0002095_abnormal_skin_pigmentation0.87581148
89MP0005410_abnormal_fertilization0.87334733
90MP0002735_abnormal_chemical_nociception0.85785878
91MP0004133_heterotaxia0.85617446
92MP0001845_abnormal_inflammatory_respons0.82984886
93MP0002429_abnormal_blood_cell0.80813766
94MP0008789_abnormal_olfactory_epithelium0.80151222
95MP0001873_stomach_inflammation0.80018059
96MP0002837_dystrophic_cardiac_calcinosis0.78618003
97MP0002572_abnormal_emotion/affect_behav0.76382846
98MP0002822_catalepsy0.76102659
99MP0006082_CNS_inflammation0.75174338
100MP0010155_abnormal_intestine_physiology0.73519542

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)4.19095946
2Pancreatic fibrosis (HP:0100732)3.52682455
3True hermaphroditism (HP:0010459)3.51028572
4Abnormality of midbrain morphology (HP:0002418)3.41038329
5Molar tooth sign on MRI (HP:0002419)3.41038329
6Congenital stationary night blindness (HP:0007642)3.33923735
7Nephronophthisis (HP:0000090)3.31398050
8Severe combined immunodeficiency (HP:0004430)3.27884447
9Abnormality of the renal cortex (HP:0011035)3.23824923
10Thyroiditis (HP:0100646)3.23589636
11Stomatitis (HP:0010280)3.07935111
12Renal cortical cysts (HP:0000803)3.04497688
13Panhypogammaglobulinemia (HP:0003139)3.02658932
14Abnormality of the renal medulla (HP:0100957)3.00237025
15Chronic hepatic failure (HP:0100626)2.93272525
16Stomach cancer (HP:0012126)2.92495899
17Hyperventilation (HP:0002883)2.88171002
18Medial flaring of the eyebrow (HP:0010747)2.82701008
19IgG deficiency (HP:0004315)2.81447804
20Abnormal biliary tract physiology (HP:0012439)2.73633487
21Bile duct proliferation (HP:0001408)2.73633487
22Abnormality of T cell number (HP:0011839)2.72612936
23T lymphocytopenia (HP:0005403)2.72575345
24Elevated erythrocyte sedimentation rate (HP:0003565)2.64663314
25Attenuation of retinal blood vessels (HP:0007843)2.60282810
26Abnormality of eosinophils (HP:0001879)2.50035570
27Abnormality of B cell number (HP:0010975)2.49604555
28Combined immunodeficiency (HP:0005387)2.43346618
29Abolished electroretinogram (ERG) (HP:0000550)2.38567215
30Abnormal delayed hypersensitivity skin test (HP:0002963)2.34103339
31Type II lissencephaly (HP:0007260)2.29804942
32Cystic liver disease (HP:0006706)2.27672754
33Abnormality of T cells (HP:0002843)2.25486575
34Congenital primary aphakia (HP:0007707)2.21884830
35Gait imbalance (HP:0002141)2.20162428
363-Methylglutaconic aciduria (HP:0003535)2.19578016
37Gaze-evoked nystagmus (HP:0000640)2.16592110
38Febrile seizures (HP:0002373)2.14887070
39Abnormal rod and cone electroretinograms (HP:0008323)2.12996601
40Recurrent cutaneous fungal infections (HP:0011370)2.12988440
41Chronic mucocutaneous candidiasis (HP:0002728)2.12988440
42Nephrogenic diabetes insipidus (HP:0009806)2.11273947
43Progressive inability to walk (HP:0002505)2.08825497
44B lymphocytopenia (HP:0010976)2.08372039
45Eosinophilia (HP:0001880)2.08079178
46Abnormality of the prostate (HP:0008775)2.06807327
47Inability to walk (HP:0002540)2.06633558
48Decreased electroretinogram (ERG) amplitude (HP:0000654)2.03025645
49Polydipsia (HP:0001959)2.02386804
50Abnormal drinking behavior (HP:0030082)2.02386804
51Constricted visual fields (HP:0001133)2.00381840
52Absent speech (HP:0001344)1.98565959
53Recurrent fungal infections (HP:0002841)1.98120297
54Broad-based gait (HP:0002136)1.97532293
55Protruding tongue (HP:0010808)1.97038205
56Hypothermia (HP:0002045)1.94937095
57Mitochondrial inheritance (HP:0001427)1.93862097
58Absent/shortened dynein arms (HP:0200106)1.93457869
59Dynein arm defect of respiratory motile cilia (HP:0012255)1.93457869
60Leukocytosis (HP:0001974)1.93364318
61Hypoplasia of the thymus (HP:0000778)1.92492196
62Agammaglobulinemia (HP:0004432)1.92330376
63Widely spaced teeth (HP:0000687)1.92054014
64Hypoproteinemia (HP:0003075)1.91999731
65Absent rod-and cone-mediated responses on ERG (HP:0007688)1.91525069
66Clumsiness (HP:0002312)1.90921670
67Decreased central vision (HP:0007663)1.90040258
68Colon cancer (HP:0003003)1.88745408
69Increased CSF lactate (HP:0002490)1.88585481
70Fair hair (HP:0002286)1.86199201
71Congenital hepatic fibrosis (HP:0002612)1.83037287
72Lipid accumulation in hepatocytes (HP:0006561)1.81834890
73Acute necrotizing encephalopathy (HP:0006965)1.80152505
74Encephalitis (HP:0002383)1.79911934
75Postaxial foot polydactyly (HP:0001830)1.78741489
76Progressive macrocephaly (HP:0004481)1.77882646
77Dialeptic seizures (HP:0011146)1.75480088
78Aplasia/Hypoplasia of the tongue (HP:0010295)1.74278987
79Male pseudohermaphroditism (HP:0000037)1.72742301
80Prostate neoplasm (HP:0100787)1.71823941
81Tubular atrophy (HP:0000092)1.71340803
82Cerebellar dysplasia (HP:0007033)1.70540906
83Abnormality of T cell physiology (HP:0011840)1.70118826
84Clubbing of toes (HP:0100760)1.67569600
85Abnormality of the pons (HP:0007361)1.66913261
86Optic disc pallor (HP:0000543)1.66896062
87Genital tract atresia (HP:0001827)1.66575772
88Atonic seizures (HP:0010819)1.65770305
89Progressive cerebellar ataxia (HP:0002073)1.65183994
90Hypoplasia of the pons (HP:0012110)1.63608078
91Abnormality of macular pigmentation (HP:0008002)1.63321227
92Anencephaly (HP:0002323)1.62807756
93Sclerocornea (HP:0000647)1.62451408
94Autoimmune hemolytic anemia (HP:0001890)1.62323069
95Focal motor seizures (HP:0011153)1.61425410
96Lissencephaly (HP:0001339)1.61032737
97Aplasia/Hypoplasia of the tibia (HP:0005772)1.60854188
98Furrowed tongue (HP:0000221)1.60724369
99Dyskinesia (HP:0100660)1.60321920
100Vaginal atresia (HP:0000148)1.60209825

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK4.88040248
2TXK4.06060836
3MAP4K23.07006346
4TAOK32.72551962
5ZAK2.57290610
6NUAK12.54393225
7ADRBK22.53169699
8BMPR1B2.50062313
9ACVR1B2.16095015
10TEC2.10155527
11MAPK131.97134183
12MAP4K11.86301903
13WNK31.70137625
14ITK1.67617753
15CAMKK21.66216939
16GRK11.61987550
17PINK11.54064202
18KIT1.53526612
19INSRR1.41602128
20FES1.38489171
21TLK11.37653480
22IKBKB1.34961156
23TRIM281.33301824
24MAP3K41.26121545
25IKBKE1.25184875
26TIE11.24771031
27EIF2AK31.22710766
28SYK1.20870246
29MARK31.12516045
30MKNK21.12236729
31NLK1.09409935
32VRK11.03934227
33BTK1.02582611
34TNIK0.96380716
35LCK0.94277409
36PRKCQ0.93092408
37MAP3K140.92377652
38BCKDK0.90936659
39LYN0.88732574
40TNK20.87734411
41OXSR10.86303961
42ERBB30.84306149
43CDK190.83740601
44PASK0.80253320
45IRAK10.77754473
46GRK60.77734540
47WNK40.76959465
48CASK0.76727267
49GRK70.75688004
50JAK30.75060717
51AKT30.72708951
52PAK30.69817010
53PIK3CA0.67212828
54CHUK0.67152454
55MAP2K70.65025951
56PIK3CG0.64410307
57HCK0.63643000
58DYRK20.63453548
59MKNK10.62229040
60TGFBR10.61987346
61BRD40.60304420
62ADRBK10.59915606
63BCR0.58494326
64BMPR20.57538979
65RPS6KA50.55496867
66CAMKK10.54104422
67FGFR20.53855130
68PIM10.53679144
69SIK20.53138294
70CSNK1G10.50056439
71PRKCE0.49704002
72STK38L0.49464929
73CSNK1A1L0.48581695
74CSNK1G30.48301442
75CDK30.47264616
76EPHA30.46963700
77IGF1R0.46649465
78PLK20.46490686
79DYRK1A0.45891168
80KDR0.45252744
81MST40.45156069
82MUSK0.45022770
83MAP2K60.44844787
84TRPM70.44740132
85CSNK1G20.44358170
86STK160.43661647
87SGK20.43641982
88ATR0.43094865
89STK390.42501331
90ABL10.42011526
91EIF2AK20.41142612
92FLT30.41091473
93RPS6KA40.40966471
94SIK30.40724371
95JAK10.40511721
96BRSK20.38834577
97STK110.38761807
98PRKCG0.38280150
99CAMK40.38279840
100SRPK10.36953722

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.50265579
2Intestinal immune network for IgA production_Homo sapiens_hsa046722.60045555
3Allograft rejection_Homo sapiens_hsa053302.45325135
4Asthma_Homo sapiens_hsa053102.45168556
5Graft-versus-host disease_Homo sapiens_hsa053322.36981914
6Phototransduction_Homo sapiens_hsa047442.36082764
7Autoimmune thyroid disease_Homo sapiens_hsa053202.34583143
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.28480510
9Type I diabetes mellitus_Homo sapiens_hsa049402.12203115
10Linoleic acid metabolism_Homo sapiens_hsa005911.87013939
11Homologous recombination_Homo sapiens_hsa034401.83444524
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.79422923
13Fanconi anemia pathway_Homo sapiens_hsa034601.78795685
14Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.71952853
15Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.70052454
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.66260558
17RNA degradation_Homo sapiens_hsa030181.63982891
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.63648680
19Butanoate metabolism_Homo sapiens_hsa006501.61851345
20Nitrogen metabolism_Homo sapiens_hsa009101.59374714
21Basal transcription factors_Homo sapiens_hsa030221.56962558
22Protein export_Homo sapiens_hsa030601.54382531
23Hematopoietic cell lineage_Homo sapiens_hsa046401.51346156
24Oxidative phosphorylation_Homo sapiens_hsa001901.47917802
25RNA polymerase_Homo sapiens_hsa030201.40922776
26Regulation of autophagy_Homo sapiens_hsa041401.39772905
27Caffeine metabolism_Homo sapiens_hsa002321.37462383
28NOD-like receptor signaling pathway_Homo sapiens_hsa046211.37168956
29Nicotine addiction_Homo sapiens_hsa050331.35160976
30Antigen processing and presentation_Homo sapiens_hsa046121.34547014
31Rheumatoid arthritis_Homo sapiens_hsa053231.30788818
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.30302399
33Ether lipid metabolism_Homo sapiens_hsa005651.29647886
34T cell receptor signaling pathway_Homo sapiens_hsa046601.29118755
35Taste transduction_Homo sapiens_hsa047421.27905299
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.25002644
37Olfactory transduction_Homo sapiens_hsa047401.24529878
38Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.23226291
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.21494858
40NF-kappa B signaling pathway_Homo sapiens_hsa040641.11857240
41Morphine addiction_Homo sapiens_hsa050321.11236665
42Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.10958895
43RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.07851330
44Tryptophan metabolism_Homo sapiens_hsa003801.05297125
45Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.05045851
46Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.02425719
47Parkinsons disease_Homo sapiens_hsa050121.00699392
48SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99875778
49Selenocompound metabolism_Homo sapiens_hsa004500.99867821
50Jak-STAT signaling pathway_Homo sapiens_hsa046300.98482813
51Non-homologous end-joining_Homo sapiens_hsa034500.95415203
52Measles_Homo sapiens_hsa051620.88434955
53Chemical carcinogenesis_Homo sapiens_hsa052040.84854667
54Collecting duct acid secretion_Homo sapiens_hsa049660.84483111
55Staphylococcus aureus infection_Homo sapiens_hsa051500.82022686
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.80039634
57Leishmaniasis_Homo sapiens_hsa051400.79962037
58ABC transporters_Homo sapiens_hsa020100.79244232
59Herpes simplex infection_Homo sapiens_hsa051680.79087946
60Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.77800925
61Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.76747214
62Arachidonic acid metabolism_Homo sapiens_hsa005900.75443937
63Peroxisome_Homo sapiens_hsa041460.75431950
64Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.74169295
65Serotonergic synapse_Homo sapiens_hsa047260.73424040
66Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.71926364
67GABAergic synapse_Homo sapiens_hsa047270.70319957
68Propanoate metabolism_Homo sapiens_hsa006400.69257814
69Primary bile acid biosynthesis_Homo sapiens_hsa001200.69150430
70Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.69067087
71Circadian entrainment_Homo sapiens_hsa047130.68483733
72Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.65673275
73Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.60736730
74Steroid hormone biosynthesis_Homo sapiens_hsa001400.59076158
75Systemic lupus erythematosus_Homo sapiens_hsa053220.55929715
76Transcriptional misregulation in cancer_Homo sapiens_hsa052020.55486861
77Glycerolipid metabolism_Homo sapiens_hsa005610.53759263
78Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.53239708
79Retinol metabolism_Homo sapiens_hsa008300.52474926
80One carbon pool by folate_Homo sapiens_hsa006700.52424471
81Glutamatergic synapse_Homo sapiens_hsa047240.52229180
82Huntingtons disease_Homo sapiens_hsa050160.51467001
83Alzheimers disease_Homo sapiens_hsa050100.49616539
84Proteasome_Homo sapiens_hsa030500.48577213
85Calcium signaling pathway_Homo sapiens_hsa040200.48202707
86Salivary secretion_Homo sapiens_hsa049700.46057283
87Tuberculosis_Homo sapiens_hsa051520.45952352
88Viral myocarditis_Homo sapiens_hsa054160.43426850
89Ovarian steroidogenesis_Homo sapiens_hsa049130.42820403
90Purine metabolism_Homo sapiens_hsa002300.42166139
91Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.41473431
92Osteoclast differentiation_Homo sapiens_hsa043800.39130933
93Spliceosome_Homo sapiens_hsa030400.39127650
94Legionellosis_Homo sapiens_hsa051340.38151170
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.35863697
96Chemokine signaling pathway_Homo sapiens_hsa040620.33232784
97Insulin secretion_Homo sapiens_hsa049110.31638579
98TNF signaling pathway_Homo sapiens_hsa046680.29085447
99Cholinergic synapse_Homo sapiens_hsa047250.28592817
100B cell receptor signaling pathway_Homo sapiens_hsa046620.28261370

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »