RRP7A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1GDP-mannose metabolic process (GO:0019673)5.28460022
2DNA deamination (GO:0045006)5.20635456
3viral transcription (GO:0019083)4.66304033
4ribosomal small subunit assembly (GO:0000028)4.64349335
5formation of translation preinitiation complex (GO:0001731)4.60987438
6translational termination (GO:0006415)4.55318274
7maturation of SSU-rRNA (GO:0030490)4.44715518
8translational elongation (GO:0006414)4.37812830
9IMP biosynthetic process (GO:0006188)4.23862748
10DNA strand elongation involved in DNA replication (GO:0006271)4.23573070
11nucleobase biosynthetic process (GO:0046112)4.18332085
12translational initiation (GO:0006413)4.16943780
13ribosome biogenesis (GO:0042254)4.07612266
14regulation of translational termination (GO:0006449)4.06122240
15folic acid-containing compound biosynthetic process (GO:0009396)4.02140132
16DNA strand elongation (GO:0022616)3.98057048
17DNA unwinding involved in DNA replication (GO:0006268)3.94839362
18ribosomal large subunit biogenesis (GO:0042273)3.91881105
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.91458504
20telomere maintenance via semi-conservative replication (GO:0032201)3.89884305
21rRNA modification (GO:0000154)3.85531705
22SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.83879896
23ribonucleoprotein complex biogenesis (GO:0022613)3.82497444
24peptidyl-arginine omega-N-methylation (GO:0035247)3.74759890
25IMP metabolic process (GO:0046040)3.74300243
26protein targeting to ER (GO:0045047)3.73035837
27cellular protein complex disassembly (GO:0043624)3.72714100
28cotranslational protein targeting to membrane (GO:0006613)3.69836741
29mitotic nuclear envelope disassembly (GO:0007077)3.66630394
30purine nucleobase biosynthetic process (GO:0009113)3.63817611
31regulation of mitochondrial translation (GO:0070129)3.63452365
32protein localization to kinetochore (GO:0034501)3.62872289
33DNA replication initiation (GO:0006270)3.60373491
34viral life cycle (GO:0019058)3.59714988
35establishment of protein localization to endoplasmic reticulum (GO:0072599)3.53988748
36ribosomal small subunit biogenesis (GO:0042274)3.53825135
37tRNA methylation (GO:0030488)3.51092326
38ribosome assembly (GO:0042255)3.49247303
39membrane disassembly (GO:0030397)3.48833378
40nuclear envelope disassembly (GO:0051081)3.48833378
41protein localization to endoplasmic reticulum (GO:0070972)3.48023951
42protein complex disassembly (GO:0043241)3.46229290
43regulation of translational fidelity (GO:0006450)3.43764144
44rRNA processing (GO:0006364)3.38329790
45rRNA methylation (GO:0031167)3.37858427
46regulation of protein heterodimerization activity (GO:0043497)3.34905899
47mitotic G1 DNA damage checkpoint (GO:0031571)3.31240070
48macromolecular complex disassembly (GO:0032984)3.30295012
49UV protection (GO:0009650)3.29314879
50DNA strand renaturation (GO:0000733)3.28401931
51rRNA metabolic process (GO:0016072)3.26494202
52nucleobase-containing small molecule interconversion (GO:0015949)3.24409711
53spliceosomal snRNP assembly (GO:0000387)3.23874409
54nuclear envelope reassembly (GO:0031468)3.23503298
55mitotic nuclear envelope reassembly (GO:0007084)3.23503298
56peptidyl-arginine N-methylation (GO:0035246)3.22400174
57peptidyl-arginine methylation (GO:0018216)3.22400174
58histone arginine methylation (GO:0034969)3.22210771
59base-excision repair, AP site formation (GO:0006285)3.22208221
60protein localization to chromosome, centromeric region (GO:0071459)3.21733862
61telomere maintenance via recombination (GO:0000722)3.21099441
62pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.18724227
63negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.17803607
64metallo-sulfur cluster assembly (GO:0031163)3.17442014
65iron-sulfur cluster assembly (GO:0016226)3.17442014
66pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.16919070
67rRNA transcription (GO:0009303)3.16590382
68tRNA modification (GO:0006400)3.13272821
69pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.12614899
70meiotic chromosome segregation (GO:0045132)3.11213115
71proline biosynthetic process (GO:0006561)3.07599636
72pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.04847152
73negative regulation of RNA splicing (GO:0033119)3.04091309
74transcription elongation from RNA polymerase III promoter (GO:0006385)3.02422432
75termination of RNA polymerase III transcription (GO:0006386)3.02422432
76pseudouridine synthesis (GO:0001522)3.02137830
77translation (GO:0006412)3.00994235
78pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.98708574
79mitotic chromosome condensation (GO:0007076)2.98289984
80telomere maintenance via telomere lengthening (GO:0010833)2.97463183
81DNA replication-dependent nucleosome assembly (GO:0006335)2.97364176
82DNA replication-dependent nucleosome organization (GO:0034723)2.97364176
83nuclear-transcribed mRNA catabolic process (GO:0000956)2.97036086
84mitotic sister chromatid segregation (GO:0000070)2.96220831
85mitotic recombination (GO:0006312)2.95713855
86UTP biosynthetic process (GO:0006228)2.95657901
87transcription from mitochondrial promoter (GO:0006390)2.94878411
88ncRNA 3-end processing (GO:0043628)2.93017684
89pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.91413766
90nucleotide salvage (GO:0043173)2.90240552
91nuclear envelope organization (GO:0006998)2.88567125
92mitotic G1/S transition checkpoint (GO:0044819)2.88206118
93DNA replication checkpoint (GO:0000076)2.87261258
94dosage compensation (GO:0007549)2.85026398
95protein maturation by protein folding (GO:0022417)2.84783332
96RNA catabolic process (GO:0006401)2.83508751
97negative regulation of B cell apoptotic process (GO:0002903)2.82581838
98establishment of integrated proviral latency (GO:0075713)2.81517622
99CTP metabolic process (GO:0046036)2.80640905
100CTP biosynthetic process (GO:0006241)2.80640905
101mRNA catabolic process (GO:0006402)2.79575367
102pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.78409839
103pyrimidine-containing compound salvage (GO:0008655)2.77530114
104pyrimidine nucleoside salvage (GO:0043097)2.77530114
105maturation of 5.8S rRNA (GO:0000460)2.77233915
106mitochondrial RNA metabolic process (GO:0000959)2.77133522
107negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.76843313
108regulation of mammary gland epithelial cell proliferation (GO:0033599)2.76737620
109base-excision repair (GO:0006284)2.76052936
110nucleotide-excision repair, DNA gap filling (GO:0006297)2.75066377
111purine deoxyribonucleotide catabolic process (GO:0009155)2.74345359
112regulation of spindle organization (GO:0090224)2.74279341
113Arp2/3 complex-mediated actin nucleation (GO:0034314)2.74248439
114guanosine-containing compound biosynthetic process (GO:1901070)2.72617682
115mitochondrial DNA metabolic process (GO:0032042)2.72534607
116viral mRNA export from host cell nucleus (GO:0046784)2.71961677
117establishment of viral latency (GO:0019043)2.71889895
118nucleoside salvage (GO:0043174)2.70948913
119pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.70643087
120protein targeting to mitochondrion (GO:0006626)2.70473350
121deoxyribonucleotide catabolic process (GO:0009264)2.69587676
122folic acid metabolic process (GO:0046655)2.68766649
123mitotic metaphase plate congression (GO:0007080)2.68685246
124regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.67744060
125pyrimidine nucleotide biosynthetic process (GO:0006221)2.66933714
126anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.66210304
127spliceosomal tri-snRNP complex assembly (GO:0000244)2.66056221
128protein complex localization (GO:0031503)2.65526647
129ncRNA processing (GO:0034470)2.64524922
130pyrimidine nucleoside biosynthetic process (GO:0046134)2.64471340
131postreplication repair (GO:0006301)2.64326978
132negative regulation of mRNA processing (GO:0050686)2.64028152
133T cell apoptotic process (GO:0070231)2.63865975
134DNA duplex unwinding (GO:0032508)2.63392268
135pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)2.63240943
136UMP metabolic process (GO:0046049)2.63240943
137pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)2.63240943
138UMP biosynthetic process (GO:0006222)2.63240943
139translesion synthesis (GO:0019985)2.62511750
140negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.61500240
141negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.60960342
142negative regulation of ligase activity (GO:0051352)2.60960342
143GTP biosynthetic process (GO:0006183)2.60599948
144DNA geometric change (GO:0032392)2.60214322
145mRNA splicing, via spliceosome (GO:0000398)2.58852709
146RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.58852709
147deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.57926171
148deoxyribose phosphate catabolic process (GO:0046386)2.57826310
149pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.57423544
150pteridine-containing compound biosynthetic process (GO:0042559)2.57419150
151sister chromatid segregation (GO:0000819)2.57367400
152tRNA aminoacylation for protein translation (GO:0006418)2.57170104
153proteasome assembly (GO:0043248)2.56495962
154regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.56256505
155RNA splicing, via transesterification reactions (GO:0000375)2.56188698
156termination of RNA polymerase II transcription (GO:0006369)2.56136084
157pentose-phosphate shunt (GO:0006098)2.55688054
158cellular component biogenesis (GO:0044085)2.55594751
159protein targeting to membrane (GO:0006612)2.55187052
160spliceosomal complex assembly (GO:0000245)2.55033895
161heterochromatin organization (GO:0070828)2.53563925
162G1 DNA damage checkpoint (GO:0044783)2.53016004

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.86291983
2EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.22063734
3MYC_18555785_ChIP-Seq_MESCs_Mouse3.85871685
4FOXM1_23109430_ChIP-Seq_U2OS_Human3.08990344
5MYC_19079543_ChIP-ChIP_MESCs_Mouse2.85079663
6MYC_18358816_ChIP-ChIP_MESCs_Mouse2.66840418
7MYC_22102868_ChIP-Seq_BL_Human2.64486404
8ETS1_20019798_ChIP-Seq_JURKAT_Human2.54170568
9* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.44766877
10MYC_19030024_ChIP-ChIP_MESCs_Mouse2.42083363
11XRN2_22483619_ChIP-Seq_HELA_Human2.30451695
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.28518056
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.22007426
14EGR1_19374776_ChIP-ChIP_THP-1_Human2.15249875
15GABP_17652178_ChIP-ChIP_JURKAT_Human2.12313824
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.11507219
17EST1_17652178_ChIP-ChIP_JURKAT_Human2.06621679
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.02669657
19VDR_21846776_ChIP-Seq_THP-1_Human2.01955663
20MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.01810028
21KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.93613632
22NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.92994057
23NELFA_20434984_ChIP-Seq_ESCs_Mouse1.87267939
24TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.84505083
25GABP_19822575_ChIP-Seq_HepG2_Human1.83274769
26* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.80843728
27VDR_23849224_ChIP-Seq_CD4+_Human1.79640813
28THAP11_20581084_ChIP-Seq_MESCs_Mouse1.72781916
29* DCP1A_22483619_ChIP-Seq_HELA_Human1.69314954
30E2F1_18555785_ChIP-Seq_MESCs_Mouse1.66266977
31DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.65871825
32TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.63467701
33TTF2_22483619_ChIP-Seq_HELA_Human1.61024178
34POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.59143010
35ZFX_18555785_ChIP-Seq_MESCs_Mouse1.58033898
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.57568532
37CIITA_25753668_ChIP-Seq_RAJI_Human1.55269045
38FOXP3_21729870_ChIP-Seq_TREG_Human1.54964554
39YY1_21170310_ChIP-Seq_MESCs_Mouse1.49599339
40KLF4_18555785_ChIP-Seq_MESCs_Mouse1.49020764
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48043375
42SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.47571883
43CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.47370051
44E2F1_21310950_ChIP-Seq_MCF-7_Human1.46776623
45* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.44638965
46TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.43560816
47KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.42057206
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.40270994
49KDM5A_27292631_Chip-Seq_BREAST_Human1.39920893
50SRY_22984422_ChIP-ChIP_TESTIS_Rat1.39667794
51PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.39098346
52ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37376573
53CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.37079806
54E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.36981800
55ZNF263_19887448_ChIP-Seq_K562_Human1.35512912
56STAT3_1855785_ChIP-Seq_MESCs_Mouse1.34679413
57AR_21909140_ChIP-Seq_LNCAP_Human1.33376963
58CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.32824383
59PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.31775208
60MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.30512031
61RACK7_27058665_Chip-Seq_MCF-7_Human1.29181713
62* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.28604660
63* BCL6_27268052_Chip-Seq_Bcells_Human1.27610704
64CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.26806422
65NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.26758851
66POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26584209
67* BCOR_27268052_Chip-Seq_Bcells_Human1.26208258
68PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.25755374
69CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.25625704
70TFEB_21752829_ChIP-Seq_HELA_Human1.24609545
71ELK3_25401928_ChIP-Seq_HUVEC_Human1.24537642
72SRF_21415370_ChIP-Seq_HL-1_Mouse1.24437408
73SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.23468983
74SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.21945955
75SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.21851225
76ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.20511076
77SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.18846464
78NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.18825339
79BP1_19119308_ChIP-ChIP_Hs578T_Human1.17211579
80ELF1_17652178_ChIP-ChIP_JURKAT_Human1.17086256
81ERG_20887958_ChIP-Seq_HPC-7_Mouse1.16681791
82RARG_19884340_ChIP-ChIP_MEFs_Mouse1.16261901
83CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.14442805
84LXR_22292898_ChIP-Seq_THP-1_Human1.14162154
85ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.14130833
86RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.13182241
87KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.12612557
88* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.11771363
89MAF_26560356_Chip-Seq_TH1_Human1.11641550
90UTX_26944678_Chip-Seq_JUKART_Human1.11564906
91HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.11554224
92SA1_27219007_Chip-Seq_ERYTHROID_Human1.11144746
93HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.10321142
94CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09672084
95TCF7_22412390_ChIP-Seq_EML_Mouse1.09355964
96ELF1_20517297_ChIP-Seq_JURKAT_Human1.09076469
97* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.08967908
98FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.07855918
99CTCF_27219007_Chip-Seq_ERYTHROID_Human1.07313581
100CTCF_18555785_ChIP-Seq_MESCs_Mouse1.06526373
101CTCF_26484167_Chip-Seq_Bcells_Mouse1.06296802
102STAT4_19710469_ChIP-ChIP_TH1__Mouse1.05659998
103* SPI1_23547873_ChIP-Seq_NB4_Human1.05115930
104ATF3_27146783_Chip-Seq_COLON_Human1.04892104
105PHF8_20622854_ChIP-Seq_HELA_Human1.04184261
106NOTCH1_21737748_ChIP-Seq_TLL_Human1.04043415
107TET1_21451524_ChIP-Seq_MESCs_Mouse1.03234582
108KDM2B_26808549_Chip-Seq_DND41_Human1.03206621
109GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.03023976
110MAF_26560356_Chip-Seq_TH2_Human1.02299043
111MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.02078338
112E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00855515
113RUNX1_22412390_ChIP-Seq_EML_Mouse0.99947489
114* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.99604872
115HOXB4_20404135_ChIP-ChIP_EML_Mouse0.99137007
116MYB_21317192_ChIP-Seq_ERMYB_Mouse0.97832916
117FOXP1_21924763_ChIP-Seq_HESCs_Human0.96924281
118YY1_22570637_ChIP-Seq_MALME-3M_Human0.95814942
119VDR_24763502_ChIP-Seq_THP-1_Human0.95233385
120P68_20966046_ChIP-Seq_HELA_Human0.94777980
121GATA1_22383799_ChIP-Seq_G1ME_Mouse0.94037322
122BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.93940784

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.88452623
2MP0004957_abnormal_blastocyst_morpholog3.99552557
3MP0003111_abnormal_nucleus_morphology3.98790203
4MP0010094_abnormal_chromosome_stability3.41725782
5MP0003077_abnormal_cell_cycle3.27070175
6MP0003806_abnormal_nucleotide_metabolis2.82803107
7MP0010352_gastrointestinal_tract_polyps2.67902080
8MP0008057_abnormal_DNA_replication2.46732360
9MP0002396_abnormal_hematopoietic_system2.41642733
10MP0001730_embryonic_growth_arrest2.35646114
11MP0008007_abnormal_cellular_replicative2.35381471
12MP0000490_abnormal_crypts_of2.30087170
13MP0005451_abnormal_body_composition2.28317200
14MP0010307_abnormal_tumor_latency2.15477171
15MP0008932_abnormal_embryonic_tissue2.15462161
16MP0000350_abnormal_cell_proliferation2.12860391
17MP0003123_paternal_imprinting2.11372347
18MP0008058_abnormal_DNA_repair2.11107842
19MP0001545_abnormal_hematopoietic_system2.01343715
20MP0005397_hematopoietic_system_phenotyp2.01343715
21MP0009333_abnormal_splenocyte_physiolog1.95162381
22MP0004808_abnormal_hematopoietic_stem1.88827351
23MP0005076_abnormal_cell_differentiation1.83059240
24MP0001697_abnormal_embryo_size1.76762160
25MP0002080_prenatal_lethality1.73565258
26MP0003303_peritoneal_inflammation1.69099827
27MP0000358_abnormal_cell_content/1.65674736
28MP0006054_spinal_hemorrhage1.65465573
29MP0002019_abnormal_tumor_incidence1.62825237
30MP0003786_premature_aging1.62298165
31MP0006036_abnormal_mitochondrial_physio1.61980661
32MP0000313_abnormal_cell_death1.60573216
33MP0003172_abnormal_lysosome_physiology1.59525666
34MP0000858_altered_metastatic_potential1.58750732
35MP0006035_abnormal_mitochondrial_morpho1.53321796
36MP0002398_abnormal_bone_marrow1.53268099
37MP0004233_abnormal_muscle_weight1.52611537
38MP0005380_embryogenesis_phenotype1.52533980
39MP0001672_abnormal_embryogenesis/_devel1.52533980
40MP0009278_abnormal_bone_marrow1.52424558
41MP0008260_abnormal_autophagy1.51895919
42MP0003763_abnormal_thymus_physiology1.50788878
43MP0002148_abnormal_hypersensitivity_rea1.45193098
44MP0001986_abnormal_taste_sensitivity1.45051286
45MP0003984_embryonic_growth_retardation1.41716689
46MP0000703_abnormal_thymus_morphology1.41627693
47MP0002722_abnormal_immune_system1.41031614
48MP0005501_abnormal_skin_physiology1.40536886
49MP0002084_abnormal_developmental_patter1.38418709
50MP0000685_abnormal_immune_system1.38327702
51MP0004185_abnormal_adipocyte_glucose1.38092267
52MP0005083_abnormal_biliary_tract1.37427924
53MP0002086_abnormal_extraembryonic_tissu1.37349805
54MP0002088_abnormal_embryonic_growth/wei1.36791759
55MP0000689_abnormal_spleen_morphology1.36772832
56MP0005058_abnormal_lysosome_morphology1.32747232
57MP0003453_abnormal_keratinocyte_physiol1.30775458
58MP0003566_abnormal_cell_adhesion1.27794066
59MP0002085_abnormal_embryonic_tissue1.26976081
60MP0003705_abnormal_hypodermis_morpholog1.24462755
61MP0005023_abnormal_wound_healing1.24230911
62MP0001853_heart_inflammation1.23267036
63MP0004197_abnormal_fetal_growth/weight/1.21993221
64MP0003315_abnormal_perineum_morphology1.20860134
65MP0010030_abnormal_orbit_morphology1.20501035
66MP0002429_abnormal_blood_cell1.17537266
67MP0008877_abnormal_DNA_methylation1.16405523
68MP0003866_abnormal_defecation1.16377280
69MP0004381_abnormal_hair_follicle1.15553456
70MP0001188_hyperpigmentation1.12427324
71MP0000015_abnormal_ear_pigmentation1.11813718
72MP0005464_abnormal_platelet_physiology1.10764520
73MP0000716_abnormal_immune_system1.08575639
74MP0002877_abnormal_melanocyte_morpholog1.06415913
75MP0002089_abnormal_postnatal_growth/wei1.05947726
76MP0002653_abnormal_ependyma_morphology1.05730244
77MP0005174_abnormal_tail_pigmentation1.05585733
78MP0003283_abnormal_digestive_organ1.04768343
79MP0000750_abnormal_muscle_regeneration1.04679415
80MP0003436_decreased_susceptibility_to1.03649731
81MP0003221_abnormal_cardiomyocyte_apopto1.03430413
82MP0005387_immune_system_phenotype1.01962185
83MP0001790_abnormal_immune_system1.01962185
84MP0005384_cellular_phenotype1.01734161
85MP0005621_abnormal_cell_physiology1.01466748
86MP0001835_abnormal_antigen_presentation0.99096694
87MP0002796_impaired_skin_barrier0.99032462
88MP0002420_abnormal_adaptive_immunity0.97856687
89MP0001819_abnormal_immune_cell0.97251653
90MP0002405_respiratory_system_inflammati0.95776419
91MP0001881_abnormal_mammary_gland0.94567339
92MP0001661_extended_life_span0.94084840
93MP0005171_absent_coat_pigmentation0.93507634
94MP0003718_maternal_effect0.91404123
95MP0002452_abnormal_antigen_presenting0.90822062
96MP0002269_muscular_atrophy0.88728619
97MP0000003_abnormal_adipose_tissue0.87695728
98MP0000371_diluted_coat_color0.86269096
99MP0002723_abnormal_immune_serum0.84769687
100MP0005310_abnormal_salivary_gland0.84654121
101MP0002254_reproductive_system_inflammat0.84620863
102MP0003300_gastrointestinal_ulcer0.84322553
103MP0009931_abnormal_skin_appearance0.84229232
104MP0002419_abnormal_innate_immunity0.83078309
105MP0001800_abnormal_humoral_immune0.82353525
106MP0008770_decreased_survivor_rate0.81685969
107MP0010155_abnormal_intestine_physiology0.81525358
108MP0001216_abnormal_epidermal_layer0.81056906
109MP0005000_abnormal_immune_tolerance0.80751364
110MP0002163_abnormal_gland_morphology0.80445866
111MP0003136_yellow_coat_color0.79999995
112MP0000477_abnormal_intestine_morphology0.79760457
113MP0005330_cardiomyopathy0.79739664
114MP0001348_abnormal_lacrimal_gland0.79674768
115MP0004947_skin_inflammation0.79309676
116MP0001845_abnormal_inflammatory_respons0.77847164
117MP0003448_altered_tumor_morphology0.77601578
118MP0000678_abnormal_parathyroid_gland0.77335421
119MP0005671_abnormal_response_to0.77224393
120MP0008961_abnormal_basal_metabolism0.75562516
121MP0001293_anophthalmia0.75376417
122MP0000747_muscle_weakness0.74395607
123MP0001873_stomach_inflammation0.73469588
124MP0004858_abnormal_nervous_system0.73148055
125MP0002006_tumorigenesis0.72144328
126MP0003567_abnormal_fetal_cardiomyocyte0.72025569
127MP0002166_altered_tumor_susceptibility0.70300987
128MP0005025_abnormal_response_to0.68066923
129MP0005075_abnormal_melanosome_morpholog0.66979955
130MP0001849_ear_inflammation0.66841080
131MP0009840_abnormal_foam_cell0.65497510
132MP0001145_abnormal_male_reproductive0.64853148
133MP0003119_abnormal_digestive_system0.64739225
134MP0000537_abnormal_urethra_morphology0.61547909

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.39840366
2Abnormal number of erythroid precursors (HP:0012131)4.29777116
3Ragged-red muscle fibers (HP:0003200)4.12184879
4Microvesicular hepatic steatosis (HP:0001414)4.07005868
5Testicular atrophy (HP:0000029)3.84412352
6Reticulocytopenia (HP:0001896)3.50453374
7Thrombocytosis (HP:0001894)3.50184043
8Selective tooth agenesis (HP:0001592)3.26213393
9Progressive muscle weakness (HP:0003323)3.22486713
10Degeneration of anterior horn cells (HP:0002398)3.21816519
11Abnormality of the anterior horn cell (HP:0006802)3.21816519
12Cerebral hypomyelination (HP:0006808)3.06043248
13Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.02172132
14Squamous cell carcinoma (HP:0002860)3.01542254
15Aplastic anemia (HP:0001915)2.97550131
16Reduced antithrombin III activity (HP:0001976)2.87705109
17Hyperacusis (HP:0010780)2.86218296
18Type I transferrin isoform profile (HP:0003642)2.83070203
19Pallor (HP:0000980)2.77195294
20Poikiloderma (HP:0001029)2.76898780
21Ependymoma (HP:0002888)2.71155885
22Trismus (HP:0000211)2.70107117
23Carpal bone hypoplasia (HP:0001498)2.67979305
24Multiple enchondromatosis (HP:0005701)2.63823935
25Atrophy/Degeneration involving motor neurons (HP:0007373)2.61779847
26Progressive external ophthalmoplegia (HP:0000590)2.61499562
27Agnosia (HP:0010524)2.61338850
28Increased neuronal autofluorescent lipopigment (HP:0002074)2.61299773
29Abnormal trabecular bone morphology (HP:0100671)2.59070156
30Personality changes (HP:0000751)2.57327375
31Basal cell carcinoma (HP:0002671)2.56217005
3211 pairs of ribs (HP:0000878)2.53197322
33Intestinal fistula (HP:0100819)2.51432261
34Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.48837650
35Abnormal protein N-linked glycosylation (HP:0012347)2.48837650
36Abnormal protein glycosylation (HP:0012346)2.48837650
37Abnormal glycosylation (HP:0012345)2.48837650
38Cerebral aneurysm (HP:0004944)2.48703979
39Vaginal fistula (HP:0004320)2.47385199
40Chromosomal breakage induced by crosslinking agents (HP:0003221)2.47034556
41Rectovaginal fistula (HP:0000143)2.46263436
42Rectal fistula (HP:0100590)2.46263436
43Nasal polyposis (HP:0100582)2.44249480
44Hand muscle atrophy (HP:0009130)2.42939901
45Broad distal phalanx of finger (HP:0009836)2.42281454
46Rough bone trabeculation (HP:0100670)2.41391322
47Increased cerebral lipofuscin (HP:0011813)2.40928994
48Macrocytic anemia (HP:0001972)2.39943306
49Hypergonadotropic hypogonadism (HP:0000815)2.38476277
50Premature ovarian failure (HP:0008209)2.38317770
51Spinal muscular atrophy (HP:0007269)2.33125652
52Annular pancreas (HP:0001734)2.32226788
53Oral leukoplakia (HP:0002745)2.31504523
54Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.30412542
55Missing ribs (HP:0000921)2.29176147
56Birth length less than 3rd percentile (HP:0003561)2.27777175
57Ulnar bowing (HP:0003031)2.27503758
58Distal upper limb amyotrophy (HP:0007149)2.27440417
59Upper limb amyotrophy (HP:0009129)2.27440417
60Hypertensive crisis (HP:0100735)2.27178342
61Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.26950397
62Microretrognathia (HP:0000308)2.25489815
63Increased serum lactate (HP:0002151)2.24113203
64Hypoplasia of the capital femoral epiphysis (HP:0003090)2.22764518
65Breast hypoplasia (HP:0003187)2.21568661
66Cervical subluxation (HP:0003308)2.21110751
67Adenoma sebaceum (HP:0009720)2.19872718
68Angiofibromas (HP:0010615)2.19872718
69Protrusio acetabuli (HP:0003179)2.18520883
70Patellar aplasia (HP:0006443)2.18294941
71Abnormality of the nasal mucosa (HP:0000433)2.15630062
72Ureteral duplication (HP:0000073)2.14989341
73Progressive microcephaly (HP:0000253)2.14810218
74Entropion (HP:0000621)2.14686624
75Abnormality of the motor neurons (HP:0002450)2.13937753
76Abnormal neuron morphology (HP:0012757)2.13937753
77Abnormality of the lower motor neuron (HP:0002366)2.12473373
78Difficulty climbing stairs (HP:0003551)2.12198238
79Agammaglobulinemia (HP:0004432)2.10628918
80Achilles tendon contracture (HP:0001771)2.08182476
81Aplasia/Hypoplasia of the patella (HP:0006498)2.07789655
82Cleft eyelid (HP:0000625)2.07731238
83Pustule (HP:0200039)2.07696749
84Poor head control (HP:0002421)2.07566464
85Hepatocellular necrosis (HP:0001404)2.06642471
86Neoplasm of the pancreas (HP:0002894)2.05593288
87Colon cancer (HP:0003003)2.03726850
88Amyotrophic lateral sclerosis (HP:0007354)2.02795765
89Increased muscle lipid content (HP:0009058)2.01789735
90Slender long bone (HP:0003100)2.01463019
91Increased intramyocellular lipid droplets (HP:0012240)2.01055167
92Increased serum ferritin (HP:0003281)2.00759103
93Pancytopenia (HP:0001876)1.98808143
94Pointed chin (HP:0000307)1.98490028
95Increased density of long bones (HP:0006392)1.98381671
96Recurrent viral infections (HP:0004429)1.98180671
97Short thumb (HP:0009778)1.97803340
98Premature graying of hair (HP:0002216)1.97431086
99Myopathic facies (HP:0002058)1.97269416
100Hypoplasia of the pons (HP:0012110)1.97234615
101Tongue fasciculations (HP:0001308)1.96745203
102Pelvic girdle muscle weakness (HP:0003749)1.96706175
103Chromsome breakage (HP:0040012)1.96221165
104Abnormal mitochondria in muscle tissue (HP:0008316)1.95688648
105Elevated erythrocyte sedimentation rate (HP:0003565)1.95409088
106Abnormality of the umbilical cord (HP:0010881)1.94886184
107Absent radius (HP:0003974)1.94749236
108Deep palmar crease (HP:0006191)1.94591083
109Muscle fibrillation (HP:0010546)1.93471904
110Prominent nose (HP:0000448)1.90887495
111Opisthotonus (HP:0002179)1.89248119
112Absent thumb (HP:0009777)1.88080570
113Ankle contracture (HP:0006466)1.87714391
114IgM deficiency (HP:0002850)1.86743948
115Abnormality of pyrimidine metabolism (HP:0004353)1.86345803
116Abnormality of the calcaneus (HP:0008364)1.86343676
117Ulnar deviation of the wrist (HP:0003049)1.86249154
118Increased CSF lactate (HP:0002490)1.86231746
119Rib fusion (HP:0000902)1.86086555
120Exercise intolerance (HP:0003546)1.85752078
121Lactic acidosis (HP:0003128)1.85311137
122Nonimmune hydrops fetalis (HP:0001790)1.82815957
123Abnormality of the distal phalanges of the toes (HP:0010182)1.81551596
124CNS hypomyelination (HP:0003429)1.80833802
125Esophageal neoplasm (HP:0100751)1.80629889
126Neoplasm of head and neck (HP:0012288)1.80629889
127Emotional lability (HP:0000712)1.79852283
128Aplasia/Hypoplasia of the thymus (HP:0010515)1.79070949
129Aplasia involving forearm bones (HP:0009822)1.78541097
130Absent forearm bone (HP:0003953)1.78541097
131Aplasia/Hypoplasia of the sacrum (HP:0008517)1.78406539
132External ophthalmoplegia (HP:0000544)1.78194756
133Shoulder girdle muscle weakness (HP:0003547)1.77978056
134Cutaneous melanoma (HP:0012056)1.76865293
135Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)1.76105255
136Chronic otitis media (HP:0000389)1.75972851
137Abnormality of the fetal cardiovascular system (HP:0010948)1.75675054
138Abnormal umbilical cord blood vessels (HP:0011403)1.75675054
139Single umbilical artery (HP:0001195)1.75675054
140Abnormality of reticulocytes (HP:0004312)1.75284629
141Mitochondrial inheritance (HP:0001427)1.75126559
142Hypercortisolism (HP:0001578)1.74707141
143Abnormality of the astrocytes (HP:0100707)1.74111275
144Astrocytoma (HP:0009592)1.74111275
145Genu recurvatum (HP:0002816)1.73664101
146IgA deficiency (HP:0002720)1.73379919
147Facial hemangioma (HP:0000329)1.73193525
148Abnormality of small intestinal villus morphology (HP:0011472)1.73026557
149Villous atrophy (HP:0011473)1.73026557
150Abnormality of the pons (HP:0007361)1.72429015
151Postnatal microcephaly (HP:0005484)1.72338632
152Abnormality of oral frenula (HP:0000190)1.71517448
153Orthostatic hypotension (HP:0001278)1.70934859
154Radial bowing (HP:0002986)1.69742475
155Glossoptosis (HP:0000162)1.68634855
156Abnormality of glycolipid metabolism (HP:0010969)1.68509148
157Abnormality of liposaccharide metabolism (HP:0010968)1.68509148
158Abnormality of glycosphingolipid metabolism (HP:0004343)1.68509148
159Abnormality of the columella (HP:0009929)1.68146118
160Dysphonia (HP:0001618)1.67742573
161Obstructive lung disease (HP:0006536)1.67282343
162Chronic obstructive pulmonary disease (HP:0006510)1.67282343
163Myelodysplasia (HP:0002863)1.66733302
164Dysautonomia (HP:0002459)1.66652629
165Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.66161351
166Dicarboxylic aciduria (HP:0003215)1.65802758
167Recurrent bronchitis (HP:0002837)1.63971576
168Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.63970300
169Decreased activity of mitochondrial respiratory chain (HP:0008972)1.63970300
170Aplasia/hypoplasia of the humerus (HP:0006507)1.63200495
171Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.62870675
172Absent epiphyses (HP:0010577)1.62870675
173Secondary amenorrhea (HP:0000869)1.62201881
174Abnormality of the Achilles tendon (HP:0005109)1.61602491
175High pitched voice (HP:0001620)1.61118447

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.22267225
2SMG13.44431136
3VRK23.38301204
4TRIB33.20616025
5WEE13.04903299
6EEF2K2.96657221
7SCYL22.71296498
8TESK22.62872720
9IRAK32.57940474
10EIF2AK12.45198074
11NEK12.41635216
12NEK22.30893872
13MAP3K112.24041894
14NME22.22063501
15CDC72.11294042
16PKN22.07845266
17PIM22.03657914
18MAP4K11.91712285
19TLK11.91111902
20ZAK1.87382868
21TESK11.77183421
22TSSK61.71824272
23PRPF4B1.59541102
24MAP3K101.56406921
25RPS6KA41.54959061
26TAOK11.54500254
27LRRK21.51658770
28PBK1.50898782
29BCKDK1.48018098
30RPS6KB21.45803649
31BLK1.45104193
32DAPK11.44953159
33PAK41.44456304
34CDK121.33261324
35MAP3K81.32557830
36BRSK21.32083873
37BRSK11.31467269
38MAPKAPK31.26167211
39ALK1.24403428
40EPHA21.23690801
41MAPK111.23503921
42PLK11.21296509
43CDK71.16229279
44VRK11.14345533
45MAP2K31.11851724
46RAF11.09109605
47ILK1.06109036
48AURKA1.06012444
49PDK21.05584863
50ZAP701.03741560
51FLT31.02820249
52STK100.98235695
53CDK190.95312253
54MAP3K140.94998017
55CDK40.93408837
56AURKB0.92965245
57EIF2AK30.92894386
58DYRK30.91474576
59ABL20.87645859
60KSR20.85146985
61PASK0.83931458
62LATS20.83914642
63ATR0.81838320
64RPS6KA50.81138655
65TXK0.80694485
66ERN10.79525386
67PIM10.79379894
68PAK10.79186230
69MAP3K90.78779596
70DAPK30.78564499
71ARAF0.77681010
72ICK0.76909760
73BMX0.75106086
74DDR20.74430381
75TTK0.72451281
76MAP2K20.72182671
77PDK30.72139839
78PDK40.72139839
79STK160.71517961
80MATK0.71090920
81LIMK10.70853689
82TBK10.70113190
83IKBKB0.70037595
84KIT0.65843559
85MST1R0.64994817
86TGFBR10.64938852
87CSNK1G30.64603290
88TTN0.63104033
89CHEK20.62931329
90KDR0.62597300
91CAMKK10.61955580
92CDK80.61939696
93CHEK10.60806181
94GRK60.58977919
95BRAF0.58296375
96IRAK20.58184165
97IRAK40.58033454
98MAP3K30.57632238
99PAK20.56556008
100CDK20.55599626
101BTK0.54906426
102TAOK20.54394851
103PRKD30.54194155
104STK40.53806192
105MTOR0.50092581
106CSNK1A1L0.50014015
107MAP3K130.49135479
108SRPK10.48222882
109CSF1R0.48213934
110PRKCI0.48053025
111NME10.47349835
112TAF10.47109308
113MAP3K120.45670488
114CDK11A0.45114340
115SYK0.44311490
116MAPK150.43808840
117CCNB10.42649544
118CSNK2A20.41814242
119PLK40.41589800
120ACVR1B0.40990615
121CDK150.39975758
122RPS6KL10.39423302
123SIK10.37386759
124MELK0.36883557
125CDK180.36257907
126RPS6KA10.34664939
127AKT20.34452055
128RPS6KA60.34220447
129UHMK10.34175626
130RPS6KC10.32151183
131IKBKE0.31957062
132MAPK120.30052989
133ERBB40.29902461
134MAP3K10.29307353

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.20972944
2Ribosome_Homo sapiens_hsa030103.49372932
3Mismatch repair_Homo sapiens_hsa034303.24829859
4* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.98888285
5Spliceosome_Homo sapiens_hsa030402.78216757
6RNA transport_Homo sapiens_hsa030132.70464276
7Base excision repair_Homo sapiens_hsa034102.68638194
8Proteasome_Homo sapiens_hsa030502.66741210
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.44857493
10RNA polymerase_Homo sapiens_hsa030202.33797590
11Nucleotide excision repair_Homo sapiens_hsa034202.21626511
12Cell cycle_Homo sapiens_hsa041101.89535314
13Pyrimidine metabolism_Homo sapiens_hsa002401.87198714
14One carbon pool by folate_Homo sapiens_hsa006701.75092574
15Homologous recombination_Homo sapiens_hsa034401.70678477
16Pentose phosphate pathway_Homo sapiens_hsa000301.43958659
17p53 signaling pathway_Homo sapiens_hsa041151.37640352
18Antigen processing and presentation_Homo sapiens_hsa046121.37346016
19mRNA surveillance pathway_Homo sapiens_hsa030151.32248747
20Epstein-Barr virus infection_Homo sapiens_hsa051691.20753437
21Oocyte meiosis_Homo sapiens_hsa041141.18289124
22Sulfur relay system_Homo sapiens_hsa041221.16180881
23Viral carcinogenesis_Homo sapiens_hsa052031.14240740
24Legionellosis_Homo sapiens_hsa051341.10310996
25Shigellosis_Homo sapiens_hsa051311.10160492
26Thyroid cancer_Homo sapiens_hsa052161.09268703
27Bladder cancer_Homo sapiens_hsa052191.08237585
28NF-kappa B signaling pathway_Homo sapiens_hsa040641.05192789
29Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.04805600
30RNA degradation_Homo sapiens_hsa030181.02917578
31Fanconi anemia pathway_Homo sapiens_hsa034601.00251641
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.00195379
33Biosynthesis of amino acids_Homo sapiens_hsa012301.00060453
34Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97037315
35Chronic myeloid leukemia_Homo sapiens_hsa052200.96260972
36Parkinsons disease_Homo sapiens_hsa050120.95420492
37mTOR signaling pathway_Homo sapiens_hsa041500.91400971
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.91303604
39Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.91227921
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.91169806
41Purine metabolism_Homo sapiens_hsa002300.90496637
42Oxidative phosphorylation_Homo sapiens_hsa001900.90338389
43N-Glycan biosynthesis_Homo sapiens_hsa005100.89139940
44Acute myeloid leukemia_Homo sapiens_hsa052210.89004342
45Central carbon metabolism in cancer_Homo sapiens_hsa052300.88894697
46Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.85982070
47Apoptosis_Homo sapiens_hsa042100.85186390
48Non-homologous end-joining_Homo sapiens_hsa034500.85053364
49Huntingtons disease_Homo sapiens_hsa050160.84146225
50Systemic lupus erythematosus_Homo sapiens_hsa053220.83588369
51HTLV-I infection_Homo sapiens_hsa051660.81889868
52Neurotrophin signaling pathway_Homo sapiens_hsa047220.81743041
53Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80046548
54Herpes simplex infection_Homo sapiens_hsa051680.79695633
55VEGF signaling pathway_Homo sapiens_hsa043700.78852961
56Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.78039890
57B cell receptor signaling pathway_Homo sapiens_hsa046620.75316268
58Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.75135526
59Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.74938771
60HIF-1 signaling pathway_Homo sapiens_hsa040660.74127369
61Basal transcription factors_Homo sapiens_hsa030220.72793081
62Non-small cell lung cancer_Homo sapiens_hsa052230.72668505
63Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.72426796
64Fructose and mannose metabolism_Homo sapiens_hsa000510.70672272
65Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.70463630
66Hepatitis B_Homo sapiens_hsa051610.68944103
67Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66593714
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.65928748
69Sulfur metabolism_Homo sapiens_hsa009200.65782755
70Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65594887
71Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.65334567
72Colorectal cancer_Homo sapiens_hsa052100.65300490
73Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.65276588
74Leishmaniasis_Homo sapiens_hsa051400.63502533
75Primary immunodeficiency_Homo sapiens_hsa053400.61220648
76Pyruvate metabolism_Homo sapiens_hsa006200.61186488
77Toll-like receptor signaling pathway_Homo sapiens_hsa046200.60011023
78Alcoholism_Homo sapiens_hsa050340.59979052
79Cyanoamino acid metabolism_Homo sapiens_hsa004600.59333752
80Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.59031045
81Intestinal immune network for IgA production_Homo sapiens_hsa046720.59022559
82Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58006614
83Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.57540159
84Small cell lung cancer_Homo sapiens_hsa052220.56898595
85Folate biosynthesis_Homo sapiens_hsa007900.55700460
86Salmonella infection_Homo sapiens_hsa051320.55266545
87Synaptic vesicle cycle_Homo sapiens_hsa047210.54309187
88Measles_Homo sapiens_hsa051620.51591096
89Glutathione metabolism_Homo sapiens_hsa004800.50497735
90Galactose metabolism_Homo sapiens_hsa000520.50201337
91Lysosome_Homo sapiens_hsa041420.49777300
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.49612810
93Glioma_Homo sapiens_hsa052140.49015694
94Endocytosis_Homo sapiens_hsa041440.47210790
95Allograft rejection_Homo sapiens_hsa053300.46603870
96Tuberculosis_Homo sapiens_hsa051520.46233850
97Carbon metabolism_Homo sapiens_hsa012000.46178714
98Notch signaling pathway_Homo sapiens_hsa043300.46073496
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.45556315
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.44341544
101Selenocompound metabolism_Homo sapiens_hsa004500.44204922
102Type I diabetes mellitus_Homo sapiens_hsa049400.44100898
103Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.43979997
104Metabolic pathways_Homo sapiens_hsa011000.43273311
105MicroRNAs in cancer_Homo sapiens_hsa052060.42957378
106Graft-versus-host disease_Homo sapiens_hsa053320.41646528
107Cysteine and methionine metabolism_Homo sapiens_hsa002700.41186342
108Autoimmune thyroid disease_Homo sapiens_hsa053200.40877456
1092-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.40834902
110Other glycan degradation_Homo sapiens_hsa005110.40529277
111Alzheimers disease_Homo sapiens_hsa050100.40097663
112Pancreatic cancer_Homo sapiens_hsa052120.37791042
113Endometrial cancer_Homo sapiens_hsa052130.37716937
114Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.37591615
115Vitamin B6 metabolism_Homo sapiens_hsa007500.37265201
116Viral myocarditis_Homo sapiens_hsa054160.36577564
117RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.36327638
118T cell receptor signaling pathway_Homo sapiens_hsa046600.35951284
119Hepatitis C_Homo sapiens_hsa051600.35819821
120AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.35813763
121TNF signaling pathway_Homo sapiens_hsa046680.35740077
122Insulin signaling pathway_Homo sapiens_hsa049100.35736735
123Influenza A_Homo sapiens_hsa051640.35213535
124Proteoglycans in cancer_Homo sapiens_hsa052050.32890920
125Thyroid hormone signaling pathway_Homo sapiens_hsa049190.32410597
126Asthma_Homo sapiens_hsa053100.31255121
127Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.30271730
128Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.29640804
129Fatty acid elongation_Homo sapiens_hsa000620.28617873

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