| 1 | Selective tooth agenesis (HP:0001592) | 3.99963634 |
| 2 | Birth length less than 3rd percentile (HP:0003561) | 3.90423945 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.88683165 |
| 4 | Reticulocytopenia (HP:0001896) | 3.81808797 |
| 5 | Multiple enchondromatosis (HP:0005701) | 3.70589079 |
| 6 | Abnormal number of erythroid precursors (HP:0012131) | 3.70229039 |
| 7 | Ependymoma (HP:0002888) | 3.52372015 |
| 8 | Oral leukoplakia (HP:0002745) | 3.39676178 |
| 9 | Breast hypoplasia (HP:0003187) | 3.32690033 |
| 10 | Trismus (HP:0000211) | 3.13843812 |
| 11 | Ragged-red muscle fibers (HP:0003200) | 3.04057465 |
| 12 | Achilles tendon contracture (HP:0001771) | 3.02656816 |
| 13 | Progressive external ophthalmoplegia (HP:0000590) | 3.01659958 |
| 14 | Hyperacusis (HP:0010780) | 2.96697746 |
| 15 | Microvesicular hepatic steatosis (HP:0001414) | 2.91447330 |
| 16 | Carpal bone hypoplasia (HP:0001498) | 2.90908796 |
| 17 | Rough bone trabeculation (HP:0100670) | 2.88189029 |
| 18 | Colon cancer (HP:0003003) | 2.78534766 |
| 19 | Patellar aplasia (HP:0006443) | 2.78019911 |
| 20 | Pallor (HP:0000980) | 2.77927189 |
| 21 | Rhabdomyosarcoma (HP:0002859) | 2.77052671 |
| 22 | Microretrognathia (HP:0000308) | 2.72655045 |
| 23 | Macrocytic anemia (HP:0001972) | 2.70903064 |
| 24 | Medulloblastoma (HP:0002885) | 2.70779797 |
| 25 | Cerebral hypomyelination (HP:0006808) | 2.67704619 |
| 26 | Degeneration of anterior horn cells (HP:0002398) | 2.67635829 |
| 27 | Abnormality of the anterior horn cell (HP:0006802) | 2.67635829 |
| 28 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.63492022 |
| 29 | Chromsome breakage (HP:0040012) | 2.61013999 |
| 30 | Abnormality of the Achilles tendon (HP:0005109) | 2.60780776 |
| 31 | Aplastic anemia (HP:0001915) | 2.58059217 |
| 32 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.53459917 |
| 33 | Rib fusion (HP:0000902) | 2.51422776 |
| 34 | Progressive muscle weakness (HP:0003323) | 2.49797565 |
| 35 | Meckel diverticulum (HP:0002245) | 2.48341675 |
| 36 | Abnormal number of incisors (HP:0011064) | 2.47958792 |
| 37 | Basal cell carcinoma (HP:0002671) | 2.47500433 |
| 38 | Premature rupture of membranes (HP:0001788) | 2.46224205 |
| 39 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.44698526 |
| 40 | Absent radius (HP:0003974) | 2.44524410 |
| 41 | Abnormality of the ileum (HP:0001549) | 2.43545795 |
| 42 | Neoplasm of the pancreas (HP:0002894) | 2.41627552 |
| 43 | Distal lower limb amyotrophy (HP:0008944) | 2.41383299 |
| 44 | Absent thumb (HP:0009777) | 2.36825676 |
| 45 | Distal lower limb muscle weakness (HP:0009053) | 2.33574700 |
| 46 | Agnosia (HP:0010524) | 2.33178458 |
| 47 | Vertebral compression fractures (HP:0002953) | 2.33156967 |
| 48 | Premature graying of hair (HP:0002216) | 2.32941925 |
| 49 | Long palpebral fissure (HP:0000637) | 2.29564496 |
| 50 | Premature ovarian failure (HP:0008209) | 2.28902582 |
| 51 | Myelodysplasia (HP:0002863) | 2.28260176 |
| 52 | Aplasia/hypoplasia of the humerus (HP:0006507) | 2.26206698 |
| 53 | Abnormality of the preputium (HP:0100587) | 2.26195757 |
| 54 | Absent forearm bone (HP:0003953) | 2.25157283 |
| 55 | Aplasia involving forearm bones (HP:0009822) | 2.25157283 |
| 56 | Ulnar bowing (HP:0003031) | 2.23853888 |
| 57 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.23507128 |
| 58 | Abnormality of chromosome stability (HP:0003220) | 2.22935300 |
| 59 | Squamous cell carcinoma (HP:0002860) | 2.20585583 |
| 60 | Neoplasm of striated muscle (HP:0009728) | 2.20059520 |
| 61 | Glossoptosis (HP:0000162) | 2.19972942 |
| 62 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.18840014 |
| 63 | Thrombocytosis (HP:0001894) | 2.17316183 |
| 64 | Insomnia (HP:0100785) | 2.16904349 |
| 65 | Increased connective tissue (HP:0009025) | 2.16718779 |
| 66 | Abnormality of the astrocytes (HP:0100707) | 2.16520749 |
| 67 | Astrocytoma (HP:0009592) | 2.16520749 |
| 68 | Proximal placement of thumb (HP:0009623) | 2.16292965 |
| 69 | Reduced subcutaneous adipose tissue (HP:0003758) | 2.15952326 |
| 70 | Atresia of the external auditory canal (HP:0000413) | 2.15856859 |
| 71 | Tracheoesophageal fistula (HP:0002575) | 2.15151928 |
| 72 | Abnormality of reticulocytes (HP:0004312) | 2.15028026 |
| 73 | Supernumerary spleens (HP:0009799) | 2.13321900 |
| 74 | Generalized amyotrophy (HP:0003700) | 2.11773138 |
| 75 | Deviation of the thumb (HP:0009603) | 2.09879642 |
| 76 | Abdominal situs inversus (HP:0003363) | 2.09417587 |
| 77 | Abnormality of abdominal situs (HP:0011620) | 2.09417587 |
| 78 | Missing ribs (HP:0000921) | 2.09294589 |
| 79 | Entropion (HP:0000621) | 2.06844742 |
| 80 | Preauricular skin tag (HP:0000384) | 2.05803059 |
| 81 | Prominent nose (HP:0000448) | 2.05282553 |
| 82 | Impulsivity (HP:0100710) | 2.03637280 |
| 83 | Sparse eyelashes (HP:0000653) | 2.03244194 |
| 84 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.02764478 |
| 85 | Single umbilical artery (HP:0001195) | 2.02764478 |
| 86 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.02764478 |
| 87 | Short nail (HP:0001799) | 2.02543405 |
| 88 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.02487097 |
| 89 | Bone marrow hypocellularity (HP:0005528) | 2.01694593 |
| 90 | Elbow flexion contracture (HP:0002987) | 1.99760942 |
| 91 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.99678849 |
| 92 | Testicular atrophy (HP:0000029) | 1.97343320 |
| 93 | Septate vagina (HP:0001153) | 1.97317305 |
| 94 | Secondary amenorrhea (HP:0000869) | 1.97089718 |
| 95 | Adenoma sebaceum (HP:0009720) | 1.96479678 |
| 96 | Angiofibromas (HP:0010615) | 1.96479678 |
| 97 | Small intestinal stenosis (HP:0012848) | 1.96353615 |
| 98 | Duodenal stenosis (HP:0100867) | 1.96353615 |
| 99 | Facial hemangioma (HP:0000329) | 1.95917708 |
| 100 | Abnormality of the umbilical cord (HP:0010881) | 1.94762138 |
| 101 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.93888554 |
| 102 | Abnormal trabecular bone morphology (HP:0100671) | 1.93762478 |
| 103 | Breech presentation (HP:0001623) | 1.93201752 |
| 104 | Hypertensive crisis (HP:0100735) | 1.91036726 |
| 105 | Slender long bone (HP:0003100) | 1.90278882 |
| 106 | Poikiloderma (HP:0001029) | 1.90189121 |
| 107 | Cellular immunodeficiency (HP:0005374) | 1.89485059 |
| 108 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.89153051 |
| 109 | Neoplasm of the oral cavity (HP:0100649) | 1.88836408 |
| 110 | Short humerus (HP:0005792) | 1.85660938 |
| 111 | Skin tags (HP:0010609) | 1.85321359 |
| 112 | Sloping forehead (HP:0000340) | 1.84108390 |
| 113 | Spinal rigidity (HP:0003306) | 1.83823054 |
| 114 | Increased nuchal translucency (HP:0010880) | 1.83415730 |
| 115 | Glioma (HP:0009733) | 1.83197641 |
| 116 | Back pain (HP:0003418) | 1.81939280 |
| 117 | Natal tooth (HP:0000695) | 1.81353425 |
| 118 | Sparse lateral eyebrow (HP:0005338) | 1.81217337 |
| 119 | Shoulder girdle muscle weakness (HP:0003547) | 1.80204494 |
| 120 | Overriding aorta (HP:0002623) | 1.80180385 |
| 121 | Cafe-au-lait spot (HP:0000957) | 1.80069657 |
| 122 | Broad distal phalanx of finger (HP:0009836) | 1.79975512 |
| 123 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.79834409 |
| 124 | Osteolytic defects of the hand bones (HP:0009699) | 1.79834409 |
| 125 | Horseshoe kidney (HP:0000085) | 1.79031245 |
| 126 | Syringomyelia (HP:0003396) | 1.78228013 |
| 127 | Spinal cord lesions (HP:0100561) | 1.78228013 |
| 128 | Spastic diplegia (HP:0001264) | 1.77264802 |
| 129 | Myopathic facies (HP:0002058) | 1.76868922 |
| 130 | Lymphoma (HP:0002665) | 1.76796886 |
| 131 | Amaurosis fugax (HP:0100576) | 1.76198130 |
| 132 | Unilateral renal agenesis (HP:0000122) | 1.75613082 |
| 133 | Pelvic girdle muscle weakness (HP:0003749) | 1.75371144 |
| 134 | Abnormality of the calcaneus (HP:0008364) | 1.74383264 |
| 135 | Megaloblastic anemia (HP:0001889) | 1.73497440 |
| 136 | Patellar dislocation (HP:0002999) | 1.73291806 |
| 137 | Increased density of long bones (HP:0006392) | 1.73263175 |
| 138 | Short 5th finger (HP:0009237) | 1.72667125 |
| 139 | Pancytopenia (HP:0001876) | 1.71828822 |
| 140 | Progressive hearing impairment (HP:0001730) | 1.71602125 |
| 141 | Protrusio acetabuli (HP:0003179) | 1.71280226 |
| 142 | Asplenia (HP:0001746) | 1.70382540 |
| 143 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.70135430 |
| 144 | Overlapping toe (HP:0001845) | 1.69240008 |
| 145 | Abnormality of the tricuspid valve (HP:0001702) | 1.69092601 |
| 146 | Premature skin wrinkling (HP:0100678) | 1.68442570 |
| 147 | Abnormality of glycolysis (HP:0004366) | 1.66790704 |
| 148 | Limb-girdle muscle atrophy (HP:0003797) | 1.65878773 |
| 149 | Hypergonadotropic hypogonadism (HP:0000815) | 1.63669067 |
| 150 | Fasciculations (HP:0002380) | 1.62279927 |
| 151 | Lower limb amyotrophy (HP:0007210) | 1.62201751 |
| 152 | Orthostatic hypotension (HP:0001278) | 1.61873559 |
| 153 | Nemaline bodies (HP:0003798) | 1.61148067 |
| 154 | Dysphonia (HP:0001618) | 1.59130983 |
| 155 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.56176215 |
| 156 | Seborrheic dermatitis (HP:0001051) | 1.55621870 |
| 157 | Ridged nail (HP:0001807) | 1.55593431 |
| 158 | Nasolacrimal duct obstruction (HP:0000579) | 1.55478289 |
| 159 | Asymmetry of the thorax (HP:0001555) | 1.54078426 |
| 160 | Abnormal gallbladder physiology (HP:0012438) | 1.53254841 |
| 161 | Cholecystitis (HP:0001082) | 1.53254841 |
| 162 | Abnormality of oral frenula (HP:0000190) | 1.53077984 |
| 163 | Difficulty climbing stairs (HP:0003551) | 1.52501129 |
| 164 | Fragile skin (HP:0001030) | 1.52365376 |
| 165 | Abnormality of the thoracic spine (HP:0100711) | 1.52199553 |
| 166 | Hypoparathyroidism (HP:0000829) | 1.52029559 |
| 167 | Urethral obstruction (HP:0000796) | 1.51675543 |
| 168 | Short clavicles (HP:0000894) | 1.50358864 |
| 169 | Nonimmune hydrops fetalis (HP:0001790) | 1.50309423 |
RRS1 
