RSL1D1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)4.92190996
2nucleobase biosynthetic process (GO:0046112)4.64295305
3DNA replication initiation (GO:0006270)4.55816914
4protein localization to kinetochore (GO:0034501)4.52057353
5purine nucleobase biosynthetic process (GO:0009113)4.50371376
6DNA strand elongation involved in DNA replication (GO:0006271)4.43286478
7DNA replication checkpoint (GO:0000076)4.38320216
8metaphase plate congression (GO:0051310)4.30697563
9formation of translation preinitiation complex (GO:0001731)4.27493228
10DNA strand elongation (GO:0022616)4.21259814
11CENP-A containing nucleosome assembly (GO:0034080)4.20915773
12DNA unwinding involved in DNA replication (GO:0006268)4.19534475
13ribosome assembly (GO:0042255)4.19068265
14chromatin remodeling at centromere (GO:0031055)4.16614382
15mitotic nuclear envelope disassembly (GO:0007077)4.14370028
16nuclear pore organization (GO:0006999)4.13958356
17ribosomal small subunit biogenesis (GO:0042274)4.10729927
18telomere maintenance via semi-conservative replication (GO:0032201)4.09537926
19IMP biosynthetic process (GO:0006188)4.08265007
20maturation of SSU-rRNA (GO:0030490)3.99311937
21ribosome biogenesis (GO:0042254)3.97932275
22establishment of integrated proviral latency (GO:0075713)3.96330014
23nuclear pore complex assembly (GO:0051292)3.94686872
24mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.91387396
25attachment of spindle microtubules to kinetochore (GO:0008608)3.91353477
26translational termination (GO:0006415)3.85753903
27protein localization to chromosome, centromeric region (GO:0071459)3.85044837
28DNA replication-independent nucleosome assembly (GO:0006336)3.84631629
29DNA replication-independent nucleosome organization (GO:0034724)3.84631629
30viral transcription (GO:0019083)3.83246329
31membrane disassembly (GO:0030397)3.82913243
32nuclear envelope disassembly (GO:0051081)3.82913243
33telomere maintenance via recombination (GO:0000722)3.82214021
34kinetochore organization (GO:0051383)3.80929551
35DNA replication-dependent nucleosome organization (GO:0034723)3.79995968
36DNA replication-dependent nucleosome assembly (GO:0006335)3.79995968
37establishment of chromosome localization (GO:0051303)3.79885309
38IMP metabolic process (GO:0046040)3.74514142
39regulation of spindle organization (GO:0090224)3.73057831
40mitotic recombination (GO:0006312)3.65538680
41SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.63981881
42ribosomal small subunit assembly (GO:0000028)3.62114175
43mitotic chromosome condensation (GO:0007076)3.61287736
44folic acid-containing compound biosynthetic process (GO:0009396)3.60175807
45maturation of 5.8S rRNA (GO:0000460)3.58420709
46histone exchange (GO:0043486)3.58338094
47cotranslational protein targeting to membrane (GO:0006613)3.57611339
48regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.55585145
49ribonucleoprotein complex biogenesis (GO:0022613)3.55180889
50protein targeting to ER (GO:0045047)3.54720326
51translation (GO:0006412)3.51055167
52kinetochore assembly (GO:0051382)3.49183751
53telomere maintenance via telomere lengthening (GO:0010833)3.47241935
54translational elongation (GO:0006414)3.44602973
55mitotic sister chromatid segregation (GO:0000070)3.41610461
56establishment of protein localization to endoplasmic reticulum (GO:0072599)3.41602809
57ribosomal large subunit biogenesis (GO:0042273)3.39730706
58negative regulation of ligase activity (GO:0051352)3.39713863
59negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.39713863
60cellular component biogenesis (GO:0044085)3.38525526
61nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.38273090
62rRNA processing (GO:0006364)3.37949208
63mitochondrial RNA metabolic process (GO:0000959)3.37773088
64rRNA methylation (GO:0031167)3.37519674
65termination of RNA polymerase III transcription (GO:0006386)3.35154736
66transcription elongation from RNA polymerase III promoter (GO:0006385)3.35154736
67transcription from mitochondrial promoter (GO:0006390)3.33541748
68spindle checkpoint (GO:0031577)3.33274700
69DNA double-strand break processing (GO:0000729)3.32876782
70protein localization to endoplasmic reticulum (GO:0070972)3.31383335
71spliceosomal snRNP assembly (GO:0000387)3.30559145
72non-recombinational repair (GO:0000726)3.29400024
73double-strand break repair via nonhomologous end joining (GO:0006303)3.29400024
74oxidative phosphorylation (GO:0006119)3.28649648
75DNA catabolic process, exonucleolytic (GO:0000738)3.28517221
76rRNA metabolic process (GO:0016072)3.28266075
77positive regulation of chromosome segregation (GO:0051984)3.25842117
78meiotic chromosome segregation (GO:0045132)3.25695333
79establishment of protein localization to mitochondrial membrane (GO:0090151)3.25431007
80nucleotide-excision repair, DNA gap filling (GO:0006297)3.25313015
81regulation of mitochondrial translation (GO:0070129)3.24621990
82negative regulation of chromosome segregation (GO:0051985)3.24195335
83negative regulation of mitotic sister chromatid separation (GO:2000816)3.23855421
84negative regulation of mitotic sister chromatid segregation (GO:0033048)3.23855421
85negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.23855421
86negative regulation of sister chromatid segregation (GO:0033046)3.23855421
87pseudouridine synthesis (GO:0001522)3.21804749
88ATP synthesis coupled proton transport (GO:0015986)3.20728859
89energy coupled proton transport, down electrochemical gradient (GO:0015985)3.20728859
90spindle assembly checkpoint (GO:0071173)3.19781712
91DNA deamination (GO:0045006)3.19768087
92regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.19229327
93negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.18763700
94rRNA modification (GO:0000154)3.18653762
95mitotic spindle assembly checkpoint (GO:0007094)3.18528717
96mitotic spindle checkpoint (GO:0071174)3.18123847
97regulation of mitotic metaphase/anaphase transition (GO:0030071)3.16755661
98regulation of mitotic spindle checkpoint (GO:1903504)3.15768540
99regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.15768540
100tRNA aminoacylation for protein translation (GO:0006418)3.13985019
101amino acid activation (GO:0043038)3.13663512
102tRNA aminoacylation (GO:0043039)3.13663512
103regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.12982508
104regulation of chromosome segregation (GO:0051983)3.12965721
105regulation of mitotic spindle organization (GO:0060236)3.12485034
106anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.12181974
107sister chromatid segregation (GO:0000819)3.08448282
108pore complex assembly (GO:0046931)3.07117748
109viral mRNA export from host cell nucleus (GO:0046784)3.05808004
110proteasome assembly (GO:0043248)3.05377749
111regulation of translational fidelity (GO:0006450)3.05195265
112transcription-coupled nucleotide-excision repair (GO:0006283)3.04268983
113DNA ligation (GO:0006266)3.04145928
114regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.03854746
115chromatin assembly or disassembly (GO:0006333)3.03710627
116signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.03644970
117signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.03644970
118signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.03644970
119mitotic sister chromatid cohesion (GO:0007064)3.03560504
120regulation of double-strand break repair via homologous recombination (GO:0010569)3.02532833
121exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.02371062
122positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.01704431
123G1/S transition of mitotic cell cycle (GO:0000082)3.01231903
124cell cycle G1/S phase transition (GO:0044843)3.01231903
125protein K6-linked ubiquitination (GO:0085020)3.00388411
126viral life cycle (GO:0019058)2.99593423
127signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.99543806
128intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.99543806
129regulation of centrosome cycle (GO:0046605)2.99275876
130signal transduction involved in DNA integrity checkpoint (GO:0072401)2.99017369
131signal transduction involved in DNA damage checkpoint (GO:0072422)2.99017369
132regulation of sister chromatid segregation (GO:0033045)2.98795551
133regulation of mitotic sister chromatid separation (GO:0010965)2.98795551
134regulation of mitotic sister chromatid segregation (GO:0033047)2.98795551
135negative regulation of RNA splicing (GO:0033119)2.98521249
136DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.98114023
137somatic hypermutation of immunoglobulin genes (GO:0016446)2.97550504
138somatic diversification of immune receptors via somatic mutation (GO:0002566)2.97550504
139translational initiation (GO:0006413)2.97289411
140termination of RNA polymerase I transcription (GO:0006363)2.96516348
141DNA duplex unwinding (GO:0032508)2.96494404
142regulation of centriole replication (GO:0046599)2.96281777
143negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.96194198
144DNA geometric change (GO:0032392)2.95663384
145transcription elongation from RNA polymerase I promoter (GO:0006362)2.95466923
146positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.95183249
147nuclear envelope organization (GO:0006998)2.95173375
148folic acid metabolic process (GO:0046655)2.93776963
149protein localization to chromosome (GO:0034502)2.91569449
150ATP-dependent chromatin remodeling (GO:0043044)2.91388409
151chromosome segregation (GO:0007059)2.89612565

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human8.86285457
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.53387577
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.95357813
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.90947895
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46006271
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.33536954
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.32168781
8EST1_17652178_ChIP-ChIP_JURKAT_Human3.06749547
9* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.05898135
10GABP_17652178_ChIP-ChIP_JURKAT_Human3.02156278
11* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.96750645
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.83899708
13* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.81995392
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.81844279
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.70003521
16* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.53335553
17AR_21909140_ChIP-Seq_LNCAP_Human2.52466618
18HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.42052199
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.34540313
20VDR_23849224_ChIP-Seq_CD4+_Human2.33900707
21XRN2_22483619_ChIP-Seq_HELA_Human2.29625667
22* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.18381358
23MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.15954835
24E2F1_21310950_ChIP-Seq_MCF-7_Human2.14688800
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.08408316
26MYCN_18555785_ChIP-Seq_MESCs_Mouse2.04720308
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.04490804
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03681212
29MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.03310568
30FOXP3_21729870_ChIP-Seq_TREG_Human2.03210632
31DCP1A_22483619_ChIP-Seq_HELA_Human1.98771678
32NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.93012221
33* GABP_19822575_ChIP-Seq_HepG2_Human1.91159547
34* TTF2_22483619_ChIP-Seq_HELA_Human1.83318811
35* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.82892719
36POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.81906784
37EGR1_19374776_ChIP-ChIP_THP-1_Human1.80318776
38YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.79733554
39ELK1_19687146_ChIP-ChIP_HELA_Human1.78679809
40THAP11_20581084_ChIP-Seq_MESCs_Mouse1.72137981
41NANOG_18555785_ChIP-Seq_MESCs_Mouse1.71820396
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.70055839
43ELF1_17652178_ChIP-ChIP_JURKAT_Human1.68289301
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.66682659
45* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.62154098
46RBPJ_22232070_ChIP-Seq_NCS_Mouse1.59774389
47MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.57224153
48CIITA_25753668_ChIP-Seq_RAJI_Human1.53981234
49HOXB4_20404135_ChIP-ChIP_EML_Mouse1.53478210
50KDM5A_27292631_Chip-Seq_BREAST_Human1.50769228
51YY1_21170310_ChIP-Seq_MESCs_Mouse1.45189042
52TP63_19390658_ChIP-ChIP_HaCaT_Human1.44921514
53TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.40259563
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.38407109
55CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.38207687
56CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.37617611
57SALL1_21062744_ChIP-ChIP_HESCs_Human1.37597826
58MYC_22102868_ChIP-Seq_BL_Human1.36500737
59* SRF_21415370_ChIP-Seq_HL-1_Mouse1.35705566
60PADI4_21655091_ChIP-ChIP_MCF-7_Human1.32357139
61NOTCH1_21737748_ChIP-Seq_TLL_Human1.29416284
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.27029985
63POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.26839909
64SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.25656354
65ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22462626
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.20916247
67ERG_20887958_ChIP-Seq_HPC-7_Mouse1.20543613
68KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18568521
69STAT3_1855785_ChIP-Seq_MESCs_Mouse1.18529431
70HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.16430080
71* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.15047483
72SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.14892152
73CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13881736
74SOX2_18555785_ChIP-Seq_MESCs_Mouse1.13250326
75TFEB_21752829_ChIP-Seq_HELA_Human1.11659351
76MYC_18940864_ChIP-ChIP_HL60_Human1.11070263
77FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.09105046
78SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.07939252
79PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.07264208
80* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.06048903
81* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05192696
82DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.01075676
83KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.97736685
84CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97302932
85CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.96840476
86HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.95515892
87BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95128158
88ELK1_22589737_ChIP-Seq_MCF10A_Human0.89784800
89NANOG_21062744_ChIP-ChIP_HESCs_Human0.89347104
90EWS_26573619_Chip-Seq_HEK293_Human0.86472828
91GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.85308380
92SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.84974053
93* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84504835
94ZNF263_19887448_ChIP-Seq_K562_Human0.84412597
95CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.81872738
96TCF3_18692474_ChIP-Seq_MEFs_Mouse0.80868915
97NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.80452866
98PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.78984092
99SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.78893662
100* SPI1_23547873_ChIP-Seq_NB4_Human0.78242849
101DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.77811321
102ELF5_23300383_ChIP-Seq_T47D_Human0.77403220
103TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.77215625
104KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.75101074
105NANOG_16153702_ChIP-ChIP_HESCs_Human0.74376402
106ESR1_15608294_ChIP-ChIP_MCF-7_Human0.73018501
107SOX17_20123909_ChIP-Seq_XEN_Mouse0.71236191
108NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.70833079
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.69913396
110CHD1_26751641_Chip-Seq_LNCaP_Human0.69495115
111NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.67199226
112* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.66539626

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.78300442
2MP0010094_abnormal_chromosome_stability4.76200408
3MP0004957_abnormal_blastocyst_morpholog4.62048948
4MP0003111_abnormal_nucleus_morphology4.34944050
5MP0003077_abnormal_cell_cycle4.16312149
6MP0008057_abnormal_DNA_replication3.92209139
7MP0008058_abnormal_DNA_repair3.50082791
8MP0008007_abnormal_cellular_replicative3.16469232
9MP0003123_paternal_imprinting2.84666196
10MP0008932_abnormal_embryonic_tissue2.80385431
11MP0008877_abnormal_DNA_methylation2.69063214
12MP0002396_abnormal_hematopoietic_system2.55429169
13MP0001730_embryonic_growth_arrest2.48678431
14MP0000350_abnormal_cell_proliferation2.33347751
15MP0003718_maternal_effect2.29710319
16MP0010352_gastrointestinal_tract_polyps2.09179519
17MP0003786_premature_aging2.06770331
18MP0006036_abnormal_mitochondrial_physio1.90976177
19MP0010307_abnormal_tumor_latency1.88757725
20MP0001672_abnormal_embryogenesis/_devel1.85597644
21MP0005380_embryogenesis_phenotype1.85597644
22MP0006035_abnormal_mitochondrial_morpho1.83031888
23MP0001697_abnormal_embryo_size1.82290048
24MP0003984_embryonic_growth_retardation1.65162675
25MP0003121_genomic_imprinting1.62776900
26MP0002080_prenatal_lethality1.60596369
27MP0002088_abnormal_embryonic_growth/wei1.59979936
28MP0002085_abnormal_embryonic_tissue1.59829924
29MP0000490_abnormal_crypts_of1.57118683
30MP0009379_abnormal_foot_pigmentation1.57108201
31MP0002084_abnormal_developmental_patter1.53053734
32MP0004808_abnormal_hematopoietic_stem1.46117137
33MP0002086_abnormal_extraembryonic_tissu1.42003967
34MP0002019_abnormal_tumor_incidence1.41183842
35MP0000313_abnormal_cell_death1.40352700
36MP0002210_abnormal_sex_determination1.39598548
37MP0004197_abnormal_fetal_growth/weight/1.38139205
38MP0003567_abnormal_fetal_cardiomyocyte1.37453934
39MP0003806_abnormal_nucleotide_metabolis1.33052597
40MP0002006_tumorigenesis1.32881108
41MP0009333_abnormal_splenocyte_physiolog1.30794466
42MP0008995_early_reproductive_senescence1.28427563
43MP0003315_abnormal_perineum_morphology1.26474213
44MP0002166_altered_tumor_susceptibility1.24893136
45MP0010030_abnormal_orbit_morphology1.24109636
46MP0003890_abnormal_embryonic-extraembry1.22999520
47MP0006292_abnormal_olfactory_placode1.22952278
48MP0005075_abnormal_melanosome_morpholog1.20665904
49MP0003763_abnormal_thymus_physiology1.18752696
50MP0001145_abnormal_male_reproductive1.17928044
51MP0001881_abnormal_mammary_gland1.16578112
52MP0001293_anophthalmia1.16418308
53MP0001119_abnormal_female_reproductive1.14499561
54MP0000653_abnormal_sex_gland1.13003767
55MP0001929_abnormal_gametogenesis1.11261509
56MP0000372_irregular_coat_pigmentation1.03364720
57MP0001661_extended_life_span1.03206902
58MP0005408_hypopigmentation0.98708201
59MP0005397_hematopoietic_system_phenotyp0.97557485
60MP0001545_abnormal_hematopoietic_system0.97557485
61MP0000703_abnormal_thymus_morphology0.97071426
62MP0003937_abnormal_limbs/digits/tail_de0.95978803
63MP0002009_preneoplasia0.94171502
64MP0002160_abnormal_reproductive_system0.93313060
65MP0009672_abnormal_birth_weight0.92555943
66MP0003186_abnormal_redox_activity0.92397564
67MP0001764_abnormal_homeostasis0.90430170
68MP0009697_abnormal_copulation0.90297996
69MP0003221_abnormal_cardiomyocyte_apopto0.87706913
70MP0006072_abnormal_retinal_apoptosis0.87596813
71MP0005076_abnormal_cell_differentiation0.86885693
72MP0005389_reproductive_system_phenotype0.86755169
73MP0009053_abnormal_anal_canal0.85841567
74MP0002398_abnormal_bone_marrow0.85619333
75MP0004147_increased_porphyrin_level0.83463090
76MP0002722_abnormal_immune_system0.82178832
77MP0003941_abnormal_skin_development0.81428907
78MP0003119_abnormal_digestive_system0.81023906
79MP0002111_abnormal_tail_morphology0.81014465
80MP0000689_abnormal_spleen_morphology0.80531368
81MP0005384_cellular_phenotype0.79710257
82MP0005501_abnormal_skin_physiology0.77951095
83MP0000358_abnormal_cell_content/0.77855473
84MP0001915_intracranial_hemorrhage0.77545565
85MP0000537_abnormal_urethra_morphology0.75657678
86MP0001873_stomach_inflammation0.75462821
87MP0006054_spinal_hemorrhage0.75192042
88MP0005023_abnormal_wound_healing0.74440482
89MP0005395_other_phenotype0.74019218
90MP0005621_abnormal_cell_physiology0.73929638
91MP0004782_abnormal_surfactant_physiolog0.72755958
92MP0003699_abnormal_female_reproductive0.72697542
93MP0002938_white_spotting0.71376642
94MP0008875_abnormal_xenobiotic_pharmacok0.70954427
95MP0001286_abnormal_eye_development0.69866848
96MP0001919_abnormal_reproductive_system0.69371569
97MP0004264_abnormal_extraembryonic_tissu0.67171916
98MP0002102_abnormal_ear_morphology0.66253809
99MP0009703_decreased_birth_body0.65549598
100MP0000858_altered_metastatic_potential0.64850783
101MP0002796_impaired_skin_barrier0.64743013
102MP0002132_abnormal_respiratory_system0.64641428
103MP0002429_abnormal_blood_cell0.63455938
104MP0003950_abnormal_plasma_membrane0.63379888
105MP0002653_abnormal_ependyma_morphology0.61867129
106MP0001835_abnormal_antigen_presentation0.61391802
107MP0000428_abnormal_craniofacial_morphol0.60968708
108MP0002877_abnormal_melanocyte_morpholog0.60898852
109MP0003787_abnormal_imprinting0.60064711
110MP0000432_abnormal_head_morphology0.58461125
111MP0004233_abnormal_muscle_weight0.58111653
112MP0005330_cardiomyopathy0.57471695
113MP0008873_increased_physiological_sensi0.57227889
114MP0002092_abnormal_eye_morphology0.56175370
115MP0000477_abnormal_intestine_morphology0.56081268
116MP0001727_abnormal_embryo_implantation0.55573494
117MP0003936_abnormal_reproductive_system0.54720725
118MP0003943_abnormal_hepatobiliary_system0.54159400
119MP0004185_abnormal_adipocyte_glucose0.53824569
120MP0004133_heterotaxia0.53483142
121MP0003698_abnormal_male_reproductive0.51600515
122MP0002161_abnormal_fertility/fecundity0.50790544
123MP0000598_abnormal_liver_morphology0.50475581
124MP0000627_abnormal_mammary_gland0.50431253
125MP0001849_ear_inflammation0.49998096
126MP0002114_abnormal_axial_skeleton0.48721442
127MP0003755_abnormal_palate_morphology0.48695489
128MP0001853_heart_inflammation0.47736742
129MP0000716_abnormal_immune_system0.47366191
130MP0005266_abnormal_metabolism0.46774014

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.69903082
2Breast hypoplasia (HP:0003187)4.15824248
3Chromsome breakage (HP:0040012)3.97338063
4Increased hepatocellular lipid droplets (HP:0006565)3.74269474
5Patellar aplasia (HP:0006443)3.67177594
6Oral leukoplakia (HP:0002745)3.58917111
7Chromosomal breakage induced by crosslinking agents (HP:0003221)3.57986366
8Microvesicular hepatic steatosis (HP:0001414)3.53866056
9Colon cancer (HP:0003003)3.53464098
10Acute necrotizing encephalopathy (HP:0006965)3.51137074
11Aplasia/Hypoplasia of the patella (HP:0006498)3.43830721
12Lipid accumulation in hepatocytes (HP:0006561)3.43434605
13Increased CSF lactate (HP:0002490)3.43349441
14Degeneration of anterior horn cells (HP:0002398)3.36493872
15Abnormality of the anterior horn cell (HP:0006802)3.36493872
16Medulloblastoma (HP:0002885)3.32178676
17Abnormal mitochondria in muscle tissue (HP:0008316)3.29197675
18Acute encephalopathy (HP:0006846)3.28951762
19Carpal bone hypoplasia (HP:0001498)3.28634923
20Abnormality of chromosome stability (HP:0003220)3.26003934
21Selective tooth agenesis (HP:0001592)3.25267810
22Reticulocytopenia (HP:0001896)3.24894980
23Mitochondrial inheritance (HP:0001427)3.17383446
24Aplastic anemia (HP:0001915)3.15598050
25Increased serum lactate (HP:0002151)3.14744053
26Type I transferrin isoform profile (HP:0003642)3.14120345
27Abnormality of the preputium (HP:0100587)3.13850958
28Meckel diverticulum (HP:0002245)3.07712381
29Abnormality of cells of the erythroid lineage (HP:0012130)3.06688654
30Abnormality of methionine metabolism (HP:0010901)3.04951767
31Abnormality of the labia minora (HP:0012880)2.98295329
32Abnormal number of erythroid precursors (HP:0012131)2.95388904
33Hepatocellular necrosis (HP:0001404)2.94419211
34Abnormality of the ileum (HP:0001549)2.88951301
35Rough bone trabeculation (HP:0100670)2.86899114
36Cerebral hypomyelination (HP:0006808)2.86176888
37Progressive macrocephaly (HP:0004481)2.85475490
38Hepatic necrosis (HP:0002605)2.84289966
39Agnosia (HP:0010524)2.81477672
40Increased serum pyruvate (HP:0003542)2.79125903
41Abnormality of glycolysis (HP:0004366)2.77758707
42Ependymoma (HP:0002888)2.77142511
43Impulsivity (HP:0100710)2.76215061
44Aplasia/Hypoplasia of the uvula (HP:0010293)2.75106379
45Cerebral edema (HP:0002181)2.73624489
46Myelodysplasia (HP:0002863)2.73371972
47Absent radius (HP:0003974)2.66050910
48Progressive muscle weakness (HP:0003323)2.65706387
49Rhabdomyosarcoma (HP:0002859)2.65658183
50Duodenal stenosis (HP:0100867)2.63545501
51Small intestinal stenosis (HP:0012848)2.63545501
52Decreased activity of mitochondrial respiratory chain (HP:0008972)2.62265588
53Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.62265588
54Absent thumb (HP:0009777)2.61062028
55Increased intramyocellular lipid droplets (HP:0012240)2.55441123
56Lactic acidosis (HP:0003128)2.54276711
57Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.52739241
58Ectopic kidney (HP:0000086)2.52044684
59Renal Fanconi syndrome (HP:0001994)2.51233999
60Abnormal lung lobation (HP:0002101)2.50478607
61Reduced antithrombin III activity (HP:0001976)2.47311513
62Absent forearm bone (HP:0003953)2.46912943
63Aplasia involving forearm bones (HP:0009822)2.46912943
64Premature graying of hair (HP:0002216)2.44805003
65Premature ovarian failure (HP:0008209)2.44026214
66Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.43946982
67Abnormal protein N-linked glycosylation (HP:0012347)2.43946982
68Abnormal protein glycosylation (HP:0012346)2.43946982
69Abnormal glycosylation (HP:0012345)2.43946982
70Microretrognathia (HP:0000308)2.43583648
71Respiratory difficulties (HP:0002880)2.41672778
72Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.41631037
73Abnormality of alanine metabolism (HP:0010916)2.41631037
74Hyperalaninemia (HP:0003348)2.41631037
75Abnormality of aspartate family amino acid metabolism (HP:0010899)2.39536619
76Supernumerary spleens (HP:0009799)2.39168897
77Sloping forehead (HP:0000340)2.39049862
78Neoplasm of the pancreas (HP:0002894)2.37718363
79Bone marrow hypocellularity (HP:0005528)2.32594708
80Exercise intolerance (HP:0003546)2.32023551
813-Methylglutaconic aciduria (HP:0003535)2.29359749
82Aplasia/Hypoplasia of the sternum (HP:0006714)2.29207551
83Secondary amenorrhea (HP:0000869)2.28693313
84Pancytopenia (HP:0001876)2.27469244
85Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.27327406
86Atresia of the external auditory canal (HP:0000413)2.26207747
8711 pairs of ribs (HP:0000878)2.25661005
88Horseshoe kidney (HP:0000085)2.22817982
89Basal cell carcinoma (HP:0002671)2.19973486
90Abnormality of the duodenum (HP:0002246)2.19578486
91Deviation of the thumb (HP:0009603)2.18819658
92Trismus (HP:0000211)2.18042838
93Megaloblastic anemia (HP:0001889)2.17058990
94Progressive external ophthalmoplegia (HP:0000590)2.15801307
95Proximal placement of thumb (HP:0009623)2.15702899
96Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.14801782
97IgM deficiency (HP:0002850)2.14670657
98Facial hemangioma (HP:0000329)2.13637078
99Abnormality of serum amino acid levels (HP:0003112)2.13227153
100Squamous cell carcinoma (HP:0002860)2.12997528
101Abnormal number of incisors (HP:0011064)2.12605555
102Multiple enchondromatosis (HP:0005701)2.12259090
103Irregular epiphyses (HP:0010582)2.09563995
104Short thumb (HP:0009778)2.08411750
105Abnormal trabecular bone morphology (HP:0100671)2.08216380
106Cellular immunodeficiency (HP:0005374)2.06314400
107Increased muscle lipid content (HP:0009058)2.05820193
108Macrocytic anemia (HP:0001972)2.05153828
109Methylmalonic acidemia (HP:0002912)2.04704135
110Glossoptosis (HP:0000162)2.04690371
111Triphalangeal thumb (HP:0001199)2.04240057
112Tracheoesophageal fistula (HP:0002575)2.03400566
113Acute myeloid leukemia (HP:0004808)2.02321073
114Atrophy/Degeneration involving motor neurons (HP:0007373)2.02067941
115Exertional dyspnea (HP:0002875)2.01944002
116Pancreatic islet-cell hyperplasia (HP:0004510)1.96237812
117Respiratory failure (HP:0002878)1.95100415
118Volvulus (HP:0002580)1.95086591
119Homocystinuria (HP:0002156)1.94119189
120Abnormality of homocysteine metabolism (HP:0010919)1.94119189
121Increased nuchal translucency (HP:0010880)1.93752489
122Cleft eyelid (HP:0000625)1.93623121
123Amaurosis fugax (HP:0100576)1.93317659
124Slender long bone (HP:0003100)1.93262282
125Abnormality of the pons (HP:0007361)1.92549240
126Testicular atrophy (HP:0000029)1.91247343
127Abnormality of placental membranes (HP:0011409)1.90992630
128Amniotic constriction ring (HP:0009775)1.90992630
129Nephroblastoma (Wilms tumor) (HP:0002667)1.90680192
130Aplasia/Hypoplasia of the sacrum (HP:0008517)1.90415924
131Neoplasm of the colon (HP:0100273)1.87901608
132Abnormality of the carotid arteries (HP:0005344)1.87834090
133Abnormal spermatogenesis (HP:0008669)1.87569580
134Hypoplasia of the pons (HP:0012110)1.86102550
135Leukodystrophy (HP:0002415)1.85707188
136Embryonal renal neoplasm (HP:0011794)1.85587541
137Thrombocytosis (HP:0001894)1.84844183
138Pallor (HP:0000980)1.82880962
139Lethargy (HP:0001254)1.81698964
140Hypoplasia of the radius (HP:0002984)1.81421186
141Cafe-au-lait spot (HP:0000957)1.81394782
142Stenosis of the external auditory canal (HP:0000402)1.80837249
143Generalized aminoaciduria (HP:0002909)1.80391645
144Sparse eyelashes (HP:0000653)1.80323534
145CNS hypomyelination (HP:0003429)1.79914188
146Abnormality of sulfur amino acid metabolism (HP:0004339)1.79794229
147Methylmalonic aciduria (HP:0012120)1.78545174
148Neoplasm of striated muscle (HP:0009728)1.78225964
149Facial cleft (HP:0002006)1.77868843
150Lymphoma (HP:0002665)1.77708514
151Neoplasm of the oral cavity (HP:0100649)1.77045172
152Abnormality of the calcaneus (HP:0008364)1.76982459
153Entropion (HP:0000621)1.76944921
154Hypoplasia of the capital femoral epiphysis (HP:0003090)1.76346947
155Optic nerve coloboma (HP:0000588)1.76272199
156Missing ribs (HP:0000921)1.76080790
157Capillary hemangiomas (HP:0005306)1.73312121
158Prominent nose (HP:0000448)1.70776674
159Muscle fiber atrophy (HP:0100295)1.70670793
160Clubbing of toes (HP:0100760)1.69824175
161Spinal muscular atrophy (HP:0007269)1.69327637

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.37476242
2CDC74.34803559
3WEE14.20302010
4EIF2AK13.55983401
5VRK23.42734440
6SRPK12.82074950
7ACVR1B2.70959839
8PLK42.62618138
9TTK2.59498941
10NEK22.52215473
11TSSK62.49312842
12BRSK22.32412828
13NEK12.24949796
14MKNK12.18428085
15EIF2AK32.17001880
16PLK12.13582785
17PLK31.94185240
18NME21.87391345
19MKNK21.80895590
20TAF11.80376681
21AURKB1.79043964
22STK161.71290396
23ATR1.69646724
24VRK11.69115120
25PASK1.65201061
26CDK71.63787682
27CHEK21.57931459
28RPS6KB21.56585041
29RPS6KA41.48371180
30STK101.36847466
31BRSK11.34580430
32CHEK11.31387436
33TESK21.29640913
34MAP3K81.29513109
35DYRK31.28237942
36AURKA1.26586010
37CDK41.22878686
38TGFBR11.22393065
39CDK121.19282336
40EPHA21.18341030
41EEF2K1.15970699
42CCNB11.14217781
43BMPR1B1.13916875
44TRIM281.11003124
45STK38L1.09206337
46PDK21.03775675
47TLK10.97787808
48CDK80.97126797
49ATM0.96264342
50ZAK0.95063772
51MELK0.93269787
52SMG10.89739277
53STK40.89473918
54BCKDK0.87533582
55CDK20.86983725
56SCYL20.83807681
57BRAF0.83554176
58PIM10.80726098
59STK30.80272588
60PIM20.80105808
61PAK40.79301486
62PBK0.78973598
63MAPKAPK50.77873056
64LATS20.74919566
65EIF2AK20.71719374
66CSNK2A20.71594773
67MAP4K20.69611502
68CSNK2A10.68504661
69CDK10.67740491
70LATS10.65170239
71ALK0.64334284
72FLT30.63624012
73CDK60.61829085
74ERBB30.61647177
75STK240.60617763
76PAK10.58750856
77DAPK10.56799907
78MAP3K120.56385263
79BRD40.55413749
80MAP4K10.52830425
81MAPKAPK30.52505554
82PRKCI0.49140080
83NEK90.46922898
84WNK40.44895410
85TEC0.43556875
86RAF10.42353838
87KDR0.42089747
88MAP3K60.41584714
89LRRK20.41089714
90PNCK0.40427661
91MAP3K110.40314685
92CSNK1E0.40301541
93MAP3K140.40263844
94MST40.40066760
95NME10.38461984
96CDK90.38135087
97PKN20.38092202
98DYRK20.37937469
99RPS6KA50.37661797
100TAOK20.37521100
101MAP3K50.36879329
102NLK0.36571821
103PAK20.34484176
104MAP2K30.34039907
105PDK30.32530842
106PDK40.32530842
107FGFR10.31499681
108PRKDC0.30690423
109STK390.29568522
110TAOK30.29155277
111AKT20.29016982
112MST1R0.28691344
113CSNK1G10.28677129
114MTOR0.27709620
115ERBB40.27404210
116NUAK10.25802654
117TESK10.24718655
118MAPK140.24662107
119CLK10.24280226
120TXK0.24224545
121RPS6KB10.23851576
122BTK0.23253607
123NEK60.21376552
124CSNK1G30.19503109
125ILK0.18750314
126CDK30.18041177
127BMPR20.17951182
128CDK190.16360445

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.72511698
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030084.19533798
3Mismatch repair_Homo sapiens_hsa034304.13023377
4RNA polymerase_Homo sapiens_hsa030203.48110321
5RNA transport_Homo sapiens_hsa030133.43623426
6Spliceosome_Homo sapiens_hsa030403.30297354
7Proteasome_Homo sapiens_hsa030503.27171472
8Cell cycle_Homo sapiens_hsa041103.03722537
9Homologous recombination_Homo sapiens_hsa034402.96214899
10Nucleotide excision repair_Homo sapiens_hsa034202.93562090
11Ribosome_Homo sapiens_hsa030102.91630785
12Base excision repair_Homo sapiens_hsa034102.91341265
13One carbon pool by folate_Homo sapiens_hsa006702.61249987
14Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.51014785
15Pyrimidine metabolism_Homo sapiens_hsa002402.47841845
16Basal transcription factors_Homo sapiens_hsa030222.34459068
17RNA degradation_Homo sapiens_hsa030182.30973933
18Non-homologous end-joining_Homo sapiens_hsa034502.28673018
19Fanconi anemia pathway_Homo sapiens_hsa034602.25593293
20Oxidative phosphorylation_Homo sapiens_hsa001901.91518232
21mRNA surveillance pathway_Homo sapiens_hsa030151.85374385
22Parkinsons disease_Homo sapiens_hsa050121.81858806
23p53 signaling pathway_Homo sapiens_hsa041151.72395836
24Purine metabolism_Homo sapiens_hsa002301.43013064
25Propanoate metabolism_Homo sapiens_hsa006401.27038176
26Epstein-Barr virus infection_Homo sapiens_hsa051691.23492979
27Pyruvate metabolism_Homo sapiens_hsa006201.17042854
28Vitamin B6 metabolism_Homo sapiens_hsa007501.13844809
29Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.09596802
30Oocyte meiosis_Homo sapiens_hsa041141.06384136
31Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.05924343
32Cysteine and methionine metabolism_Homo sapiens_hsa002701.00712440
33Herpes simplex infection_Homo sapiens_hsa051680.98499390
34Alzheimers disease_Homo sapiens_hsa050100.95144701
35Systemic lupus erythematosus_Homo sapiens_hsa053220.91573615
36Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.90387150
37Viral carcinogenesis_Homo sapiens_hsa052030.89430350
38Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.89321058
39Biosynthesis of amino acids_Homo sapiens_hsa012300.85730091
40Antigen processing and presentation_Homo sapiens_hsa046120.85360654
41Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.83174232
42Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.81399217
43Thyroid cancer_Homo sapiens_hsa052160.80191778
44Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.77482761
45Pentose phosphate pathway_Homo sapiens_hsa000300.77024055
46Fatty acid elongation_Homo sapiens_hsa000620.76653643
47Folate biosynthesis_Homo sapiens_hsa007900.74872071
48Protein export_Homo sapiens_hsa030600.74161187
49HTLV-I infection_Homo sapiens_hsa051660.72697700
50Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.71689426
51Selenocompound metabolism_Homo sapiens_hsa004500.70110024
52Drug metabolism - other enzymes_Homo sapiens_hsa009830.69221295
53Caffeine metabolism_Homo sapiens_hsa002320.66732457
54Cyanoamino acid metabolism_Homo sapiens_hsa004600.65076065
55TGF-beta signaling pathway_Homo sapiens_hsa043500.65061420
56MicroRNAs in cancer_Homo sapiens_hsa052060.64008508
57Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61482204
58Small cell lung cancer_Homo sapiens_hsa052220.54332438
59Legionellosis_Homo sapiens_hsa051340.52035336
60Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.44643935
61Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44263125
62Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.42705601
63Glutathione metabolism_Homo sapiens_hsa004800.42647965
64Carbon metabolism_Homo sapiens_hsa012000.42473517
65Steroid biosynthesis_Homo sapiens_hsa001000.41903134
66Hippo signaling pathway_Homo sapiens_hsa043900.41621540
67Intestinal immune network for IgA production_Homo sapiens_hsa046720.41358333
68Vitamin digestion and absorption_Homo sapiens_hsa049770.40922053
69Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.40675256
70Sulfur relay system_Homo sapiens_hsa041220.40385596
71Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.40322594
72Colorectal cancer_Homo sapiens_hsa052100.38221578
73Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.37282612
74Primary immunodeficiency_Homo sapiens_hsa053400.37218677
75Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36960401
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36857053
77Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.36845562
78Measles_Homo sapiens_hsa051620.35329676
79Huntingtons disease_Homo sapiens_hsa050160.33579124
80Nitrogen metabolism_Homo sapiens_hsa009100.33025429
81Lysine degradation_Homo sapiens_hsa003100.32847330
82Apoptosis_Homo sapiens_hsa042100.31889857
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31841427
84Hepatitis B_Homo sapiens_hsa051610.31674115
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31346974
86Fatty acid metabolism_Homo sapiens_hsa012120.31003993
87Cardiac muscle contraction_Homo sapiens_hsa042600.30081790
88Peroxisome_Homo sapiens_hsa041460.28654552
89Shigellosis_Homo sapiens_hsa051310.28496046
90Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.27065811
91Autoimmune thyroid disease_Homo sapiens_hsa053200.26586612
92Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.26109914
93Basal cell carcinoma_Homo sapiens_hsa052170.24637719
94N-Glycan biosynthesis_Homo sapiens_hsa005100.24383705
95NF-kappa B signaling pathway_Homo sapiens_hsa040640.23421276
96Adherens junction_Homo sapiens_hsa045200.22311785
97Tryptophan metabolism_Homo sapiens_hsa003800.21032534
98Influenza A_Homo sapiens_hsa051640.20792126
99HIF-1 signaling pathway_Homo sapiens_hsa040660.20780013
100Pathways in cancer_Homo sapiens_hsa052000.20180010
101Alcoholism_Homo sapiens_hsa050340.17862044
102Type I diabetes mellitus_Homo sapiens_hsa049400.17683487
103Metabolic pathways_Homo sapiens_hsa011000.17601631
104Bladder cancer_Homo sapiens_hsa052190.17364433
105Viral myocarditis_Homo sapiens_hsa054160.17169239
106Hematopoietic cell lineage_Homo sapiens_hsa046400.17069753
107Fructose and mannose metabolism_Homo sapiens_hsa000510.16428810
108Notch signaling pathway_Homo sapiens_hsa043300.16396679
109Arachidonic acid metabolism_Homo sapiens_hsa005900.15696591
110NOD-like receptor signaling pathway_Homo sapiens_hsa046210.15255477
111Regulation of autophagy_Homo sapiens_hsa041400.15097402
112Galactose metabolism_Homo sapiens_hsa000520.14929010
113Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.14927975
114Fatty acid degradation_Homo sapiens_hsa000710.14923760
115Allograft rejection_Homo sapiens_hsa053300.14708018
116Sulfur metabolism_Homo sapiens_hsa009200.14355311
117Arginine and proline metabolism_Homo sapiens_hsa003300.14139104
118Prostate cancer_Homo sapiens_hsa052150.13394146
119Chronic myeloid leukemia_Homo sapiens_hsa052200.13214326
120Graft-versus-host disease_Homo sapiens_hsa053320.11531669
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.11516941
122Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.11405800
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.10880030
124Butanoate metabolism_Homo sapiens_hsa006500.10794408
125Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.09847015
126Pancreatic cancer_Homo sapiens_hsa052120.09779506
127Hedgehog signaling pathway_Homo sapiens_hsa043400.09290679
128Arginine biosynthesis_Homo sapiens_hsa002200.08334736
129Phototransduction_Homo sapiens_hsa047440.07898895
130Asthma_Homo sapiens_hsa053100.07894217
131Fatty acid biosynthesis_Homo sapiens_hsa000610.07816545
132Wnt signaling pathway_Homo sapiens_hsa043100.07649701
133Jak-STAT signaling pathway_Homo sapiens_hsa046300.07300643
134Tyrosine metabolism_Homo sapiens_hsa003500.06938823

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