RSL24D1P11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)8.58366284
2negative regulation of B cell apoptotic process (GO:0002903)7.81410909
3positive regulation of gastrulation (GO:2000543)7.07208496
4regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)7.05935878
5regulation of isotype switching to IgG isotypes (GO:0048302)6.18889812
6positive regulation of interleukin-17 production (GO:0032740)5.77575036
7head development (GO:0060322)5.73290094
8immunoglobulin mediated immune response (GO:0016064)5.65505235
9behavioral response to nicotine (GO:0035095)5.60260812
10endoderm formation (GO:0001706)5.30075397
11chaperone mediated protein folding requiring cofactor (GO:0051085)5.11476518
12positive regulation of activated T cell proliferation (GO:0042104)4.99985818
13regulation of regulatory T cell differentiation (GO:0045589)4.97630111
14regulation of B cell apoptotic process (GO:0002902)4.96587134
15regulation of immunoglobulin secretion (GO:0051023)4.92095525
16positive thymic T cell selection (GO:0045059)4.83193298
17B cell mediated immunity (GO:0019724)4.46583006
18negative regulation of mast cell activation (GO:0033004)4.40926938
19telencephalon development (GO:0021537)4.40178569
20glomerulus development (GO:0032835)4.30015101
21embryonic retina morphogenesis in camera-type eye (GO:0060059)4.04056108
22primitive streak formation (GO:0090009)4.03170669
23tryptophan catabolic process (GO:0006569)3.99571458
24indole-containing compound catabolic process (GO:0042436)3.99571458
25indolalkylamine catabolic process (GO:0046218)3.99571458
26embryonic viscerocranium morphogenesis (GO:0048703)3.96936189
27regulation of nuclear cell cycle DNA replication (GO:0033262)3.91538276
28amine catabolic process (GO:0009310)3.89979742
29cellular biogenic amine catabolic process (GO:0042402)3.89979742
30DNA double-strand break processing (GO:0000729)3.82660959
31positive regulation of dendritic spine development (GO:0060999)3.79032996
32somite rostral/caudal axis specification (GO:0032525)3.77647859
33spinal cord association neuron differentiation (GO:0021527)3.74247534
34neurofilament cytoskeleton organization (GO:0060052)3.71140048
35urogenital system development (GO:0001655)3.65679605
36positive T cell selection (GO:0043368)3.51939092
37positive regulation of isotype switching (GO:0045830)3.50942172
38regulation of activated T cell proliferation (GO:0046006)3.47685028
39vagina development (GO:0060068)3.43652236
40heart field specification (GO:0003128)3.38322724
41secondary heart field specification (GO:0003139)3.38322724
42L-fucose catabolic process (GO:0042355)3.32041964
43fucose catabolic process (GO:0019317)3.32041964
44L-fucose metabolic process (GO:0042354)3.32041964
45negative regulation of lymphocyte apoptotic process (GO:0070229)3.31948697
46response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.29773160
47positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190)3.22643435
48replication fork processing (GO:0031297)3.16877754
49positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531)3.14605156
50negative regulation of heart contraction (GO:0045822)3.13834435
51uterus development (GO:0060065)3.08012559
52histone H4-K12 acetylation (GO:0043983)3.07824970
53tryptophan metabolic process (GO:0006568)3.07319615
54positive regulation of DNA recombination (GO:0045911)3.04212133
55motor neuron axon guidance (GO:0008045)2.97356602
56embryonic hemopoiesis (GO:0035162)2.97150396
57positive regulation of interferon-gamma production (GO:0032729)2.94782719
58negative regulation of membrane potential (GO:0045837)2.92614662
59kynurenine metabolic process (GO:0070189)2.91869919
60piRNA metabolic process (GO:0034587)2.88898201
61alternative mRNA splicing, via spliceosome (GO:0000380)2.87018051
62protein K6-linked ubiquitination (GO:0085020)2.85526928
63positive regulation of mesonephros development (GO:0061213)2.83069291
64positive regulation of antigen processing and presentation (GO:0002579)2.83066725
65positive regulation of protein homooligomerization (GO:0032464)2.77500608
66retinal ganglion cell axon guidance (GO:0031290)2.76588982
67polarized epithelial cell differentiation (GO:0030859)2.75641588
68regulation of gene expression by genetic imprinting (GO:0006349)2.75140469
69regulation of centriole replication (GO:0046599)2.73694036
70genetic imprinting (GO:0071514)2.73386707
71regulation of isotype switching (GO:0045191)2.71350407
72cell-cell junction maintenance (GO:0045217)2.69908806
73male meiosis I (GO:0007141)2.68432801
74aromatic amino acid family catabolic process (GO:0009074)2.67159970
75synaptic transmission, cholinergic (GO:0007271)2.63948757
76somite development (GO:0061053)2.63359221
77platelet dense granule organization (GO:0060155)2.63168922
78positive regulation of B cell proliferation (GO:0030890)2.62281869
79positive regulation of defense response to virus by host (GO:0002230)2.60443019
80female genitalia development (GO:0030540)2.58659847
81glycosylceramide metabolic process (GO:0006677)2.58303709
82indolalkylamine metabolic process (GO:0006586)2.57198241
83sulfate transmembrane transport (GO:1902358)2.56866769
84regulation of branching involved in ureteric bud morphogenesis (GO:0090189)2.56479490
85regulation of lymphocyte apoptotic process (GO:0070228)2.55407683
86regulation of interleukin-17 production (GO:0032660)2.53133792
87positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.52969305
88regulation of dendritic cell antigen processing and presentation (GO:0002604)2.51373294
89thyroid hormone metabolic process (GO:0042403)2.48778304
90magnesium ion transport (GO:0015693)2.48182840
91positive regulation of JAK-STAT cascade (GO:0046427)2.48071527
92positive regulation of T cell apoptotic process (GO:0070234)2.47966995
93regulation of tyrosine phosphorylation of STAT protein (GO:0042509)2.46357689
94retina layer formation (GO:0010842)2.46281588
95positive regulation of RNA splicing (GO:0033120)2.44698070
96sulfation (GO:0051923)2.44348800
97cerebellar Purkinje cell differentiation (GO:0021702)2.44183340
98specification of organ identity (GO:0010092)2.43691766
99negative regulation of leukocyte apoptotic process (GO:2000107)2.43464300
100axoneme assembly (GO:0035082)2.43330020

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.74326633
2GBX2_23144817_ChIP-Seq_PC3_Human3.35776679
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.33689934
4MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.28601625
5NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.88470037
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83756461
7ZNF274_21170338_ChIP-Seq_K562_Hela2.69326249
8TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.69167856
9TAF15_26573619_Chip-Seq_HEK293_Human2.59233067
10IGF1R_20145208_ChIP-Seq_DFB_Human2.48572607
11IRF8_22096565_ChIP-ChIP_GC-B_Human2.29944526
12EWS_26573619_Chip-Seq_HEK293_Human2.22253155
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.19794220
14STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.13452152
15CTBP2_25329375_ChIP-Seq_LNCAP_Human2.11620183
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.97240251
17VDR_22108803_ChIP-Seq_LS180_Human1.95517650
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.94565766
19CTBP1_25329375_ChIP-Seq_LNCAP_Human1.85250036
20SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.84705246
21PCGF2_27294783_Chip-Seq_ESCs_Mouse1.82172868
22GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.76901496
23P300_19829295_ChIP-Seq_ESCs_Human1.76295580
24GABP_17652178_ChIP-ChIP_JURKAT_Human1.74824006
25PCGF2_27294783_Chip-Seq_NPCs_Mouse1.73905829
26IKZF1_21737484_ChIP-ChIP_HCT116_Human1.72843352
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.70536742
28TP53_22573176_ChIP-Seq_HFKS_Human1.61551076
29MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58018279
30PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.56192660
31CBP_20019798_ChIP-Seq_JUKART_Human1.55709059
32IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.55709059
33BMI1_23680149_ChIP-Seq_NPCS_Mouse1.50121875
34ETV2_25802403_ChIP-Seq_MESCs_Mouse1.49779098
35KLF5_20875108_ChIP-Seq_MESCs_Mouse1.48256876
36REST_21632747_ChIP-Seq_MESCs_Mouse1.47959885
37FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.46100759
38SOX2_19829295_ChIP-Seq_ESCs_Human1.45584867
39NANOG_19829295_ChIP-Seq_ESCs_Human1.45584867
40VDR_23849224_ChIP-Seq_CD4+_Human1.39729376
41RUNX2_22187159_ChIP-Seq_PCA_Human1.38669337
42TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.38629274
43CBX2_27304074_Chip-Seq_ESCs_Mouse1.37187813
44NFE2_27457419_Chip-Seq_LIVER_Mouse1.34426301
45UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.32796388
46NCOR_22424771_ChIP-Seq_293T_Human1.32022762
47POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.30233503
48TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30233503
49SUZ12_27294783_Chip-Seq_ESCs_Mouse1.29321770
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.26791429
51CIITA_25753668_ChIP-Seq_RAJI_Human1.26652402
52FOXA1_27270436_Chip-Seq_PROSTATE_Human1.26111524
53FOXA1_25329375_ChIP-Seq_VCAP_Human1.26111524
54AR_20517297_ChIP-Seq_VCAP_Human1.25765973
55GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25708883
56GATA1_26923725_Chip-Seq_HPCs_Mouse1.25606865
57NANOG_20526341_ChIP-Seq_ESCs_Human1.24648794
58FUS_26573619_Chip-Seq_HEK293_Human1.23905209
59ER_23166858_ChIP-Seq_MCF-7_Human1.20247625
60EZH2_27294783_Chip-Seq_ESCs_Mouse1.18572150
61POU3F2_20337985_ChIP-ChIP_501MEL_Human1.18126899
62CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.16786021
63REST_18959480_ChIP-ChIP_MESCs_Mouse1.15754334
64TAF2_19829295_ChIP-Seq_ESCs_Human1.15715789
65TAL1_26923725_Chip-Seq_HPCs_Mouse1.14757995
66EZH2_27294783_Chip-Seq_NPCs_Mouse1.14542929
67MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.14043624
68SRF_21415370_ChIP-Seq_HL-1_Mouse1.13090741
69ELK1_19687146_ChIP-ChIP_HELA_Human1.12939271
70TCF4_23295773_ChIP-Seq_U87_Human1.10692748
71PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.09858486
72SMRT_27268052_Chip-Seq_Bcells_Human1.09665335
73MYC_18940864_ChIP-ChIP_HL60_Human1.08587685
74JARID2_20064375_ChIP-Seq_MESCs_Mouse1.08307917
75FOXP3_21729870_ChIP-Seq_TREG_Human1.08222055
76EST1_17652178_ChIP-ChIP_JURKAT_Human1.07160390
77POU5F1_16153702_ChIP-ChIP_HESCs_Human1.03730015
78STAT3_23295773_ChIP-Seq_U87_Human1.02339329
79ERA_21632823_ChIP-Seq_H3396_Human1.01641081
80SRY_22984422_ChIP-ChIP_TESTIS_Rat1.00654890
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.00332917
82P53_22127205_ChIP-Seq_FIBROBLAST_Human0.99247847
83ETS1_20019798_ChIP-Seq_JURKAT_Human0.99080403
84PRDM14_20953172_ChIP-Seq_ESCs_Human0.98453673
85CRX_20693478_ChIP-Seq_RETINA_Mouse0.98322857
86AUTS2_25519132_ChIP-Seq_293T-REX_Human0.98088208
87NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97818147
88JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.97544844
89FOXH1_21741376_ChIP-Seq_ESCs_Human0.97108217
90SMAD3_21741376_ChIP-Seq_ESCs_Human0.95888977
91FLI1_21867929_ChIP-Seq_TH2_Mouse0.94812885
92AR_25329375_ChIP-Seq_VCAP_Human0.94144137
93IRF8_21731497_ChIP-ChIP_J774_Mouse0.93582721
94EZH2_27304074_Chip-Seq_ESCs_Mouse0.92507219
95GATA3_21878914_ChIP-Seq_MCF-7_Human0.92484920
96CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.92339457
97YY1_21170310_ChIP-Seq_MESCs_Mouse0.91922189
98TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.91806638
99HOXB7_26014856_ChIP-Seq_BT474_Human0.91191303
100MYC_19829295_ChIP-Seq_ESCs_Human0.90897134

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003300_gastrointestinal_ulcer3.99302600
2MP0001835_abnormal_antigen_presentation3.84265375
3MP0002653_abnormal_ependyma_morphology3.48708084
4MP0005670_abnormal_white_adipose3.46967364
5MP0000538_abnormal_urinary_bladder3.17975216
6MP0003890_abnormal_embryonic-extraembry2.85485759
7MP0006072_abnormal_retinal_apoptosis2.70035366
8MP0003122_maternal_imprinting2.67078361
9MP0003183_abnormal_peptide_metabolism2.54725289
10MP0001853_heart_inflammation2.40288008
11MP0000465_gastrointestinal_hemorrhage2.28415546
12MP0008877_abnormal_DNA_methylation2.26771803
13MP0006292_abnormal_olfactory_placode2.21254732
14MP0010386_abnormal_urinary_bladder2.20351531
15MP0004133_heterotaxia2.13357667
16MP0000372_irregular_coat_pigmentation1.99722569
17MP0002638_abnormal_pupillary_reflex1.98673059
18MP0003950_abnormal_plasma_membrane1.92810466
19MP0004142_abnormal_muscle_tone1.91113001
20MP0006276_abnormal_autonomic_nervous1.87957852
21MP0002837_dystrophic_cardiac_calcinosis1.80849224
22MP0005377_hearing/vestibular/ear_phenot1.75977184
23MP0003878_abnormal_ear_physiology1.75977184
24MP0003136_yellow_coat_color1.74500706
25MP0001440_abnormal_grooming_behavior1.74191571
26MP0005645_abnormal_hypothalamus_physiol1.71865201
27MP0008875_abnormal_xenobiotic_pharmacok1.71861995
28MP0005084_abnormal_gallbladder_morpholo1.71694880
29MP0002272_abnormal_nervous_system1.71105048
30MP0008995_early_reproductive_senescence1.70724321
31MP0003121_genomic_imprinting1.67065201
32MP0000604_amyloidosis1.65510981
33MP0005551_abnormal_eye_electrophysiolog1.59311747
34MP0003787_abnormal_imprinting1.56863228
35MP0000534_abnormal_ureter_morphology1.54884258
36MP0003567_abnormal_fetal_cardiomyocyte1.54053180
37MP0008872_abnormal_physiological_respon1.53663026
38MP0005083_abnormal_biliary_tract1.48616063
39MP0002102_abnormal_ear_morphology1.47421767
40MP0003011_delayed_dark_adaptation1.46577509
41MP0001486_abnormal_startle_reflex1.36128072
42MP0005423_abnormal_somatic_nervous1.25398805
43MP0000343_altered_response_to1.21980396
44MP0002938_white_spotting1.20893849
45MP0001919_abnormal_reproductive_system1.19767315
46MP0003806_abnormal_nucleotide_metabolis1.19536623
47MP0002009_preneoplasia1.18385703
48MP0003786_premature_aging1.17524832
49MP0000778_abnormal_nervous_system1.15902989
50MP0004145_abnormal_muscle_electrophysio1.12443992
51MP0003942_abnormal_urinary_system1.11557731
52MP0002876_abnormal_thyroid_physiology1.11176763
53MP0001968_abnormal_touch/_nociception1.10806748
54MP0000566_synostosis1.10779744
55MP0005389_reproductive_system_phenotype1.10192957
56MP0005253_abnormal_eye_physiology1.08681929
57MP0009046_muscle_twitch1.08098915
58MP0002736_abnormal_nociception_after1.02602328
59MP0003937_abnormal_limbs/digits/tail_de1.01168257
60MP0000631_abnormal_neuroendocrine_gland1.01107375
61MP0000955_abnormal_spinal_cord1.00328409
62MP0003718_maternal_effect1.00039564
63MP0009745_abnormal_behavioral_response0.96428149
64MP0001293_anophthalmia0.95516104
65MP0002067_abnormal_sensory_capabilities0.94550339
66MP0002733_abnormal_thermal_nociception0.93465145
67MP0008961_abnormal_basal_metabolism0.93442228
68MP0002148_abnormal_hypersensitivity_rea0.93218292
69MP0009379_abnormal_foot_pigmentation0.88652450
70MP0001502_abnormal_circadian_rhythm0.88135028
71MP0002064_seizures0.84949337
72MP0002210_abnormal_sex_determination0.84691433
73MP0003633_abnormal_nervous_system0.84617741
74MP0002572_abnormal_emotion/affect_behav0.83544163
75MP0004885_abnormal_endolymph0.83380675
76MP0002332_abnormal_exercise_endurance0.83016396
77MP0003866_abnormal_defecation0.81247212
78MP0002928_abnormal_bile_duct0.80996653
79MP0003635_abnormal_synaptic_transmissio0.78262226
80MP0001800_abnormal_humoral_immune0.76101796
81MP0001986_abnormal_taste_sensitivity0.75216370
82MP0008058_abnormal_DNA_repair0.74644956
83MP0002063_abnormal_learning/memory/cond0.73319626
84MP0002735_abnormal_chemical_nociception0.73224182
85MP0004742_abnormal_vestibular_system0.68497207
86MP0000653_abnormal_sex_gland0.67098967
87MP0001958_emphysema0.66722740
88MP0002229_neurodegeneration0.66514273
89MP0001970_abnormal_pain_threshold0.65601687
90MP0001145_abnormal_male_reproductive0.65414971
91MP0002160_abnormal_reproductive_system0.65405549
92MP0003698_abnormal_male_reproductive0.65071081
93MP0005167_abnormal_blood-brain_barrier0.63705819
94MP0009384_cardiac_valve_regurgitation0.63428536
95MP0002405_respiratory_system_inflammati0.63272790
96MP0005391_vision/eye_phenotype0.62770808
97MP0002184_abnormal_innervation0.60831516
98MP0005195_abnormal_posterior_eye0.60278862
99MP0001929_abnormal_gametogenesis0.59971716
100MP0001485_abnormal_pinna_reflex0.59747417

Predicted human phenotypes

RankGene SetZ-score
1Type 2 muscle fiber atrophy (HP:0003554)5.65118097
2Muscle fiber atrophy (HP:0100295)4.82513808
3Hypomagnesemia (HP:0002917)4.67926042
4Abnormality of midbrain morphology (HP:0002418)4.14729892
5Molar tooth sign on MRI (HP:0002419)4.14729892
6Bell-shaped thorax (HP:0001591)4.06482382
7Abnormality of magnesium homeostasis (HP:0004921)3.96171178
8Abnormal pancreas size (HP:0012094)3.89543335
9Occipital encephalocele (HP:0002085)3.75627540
10Hypoplasia of the pons (HP:0012110)3.60665004
11Polyuria (HP:0000103)3.27437756
12Shawl scrotum (HP:0000049)3.10196294
13Abnormality of the pons (HP:0007361)3.07481050
14Nephronophthisis (HP:0000090)3.06634808
15Pancreatic cysts (HP:0001737)2.92359102
16True hermaphroditism (HP:0010459)2.89131633
17Microretrognathia (HP:0000308)2.86301338
18Absent thumb (HP:0009777)2.82782361
19Polyphagia (HP:0002591)2.76111998
20Renal salt wasting (HP:0000127)2.75220266
21Partial duplication of thumb phalanx (HP:0009944)2.72286748
22Hyperuricemia (HP:0002149)2.71203084
23Increased purine levels (HP:0004368)2.71203084
24Oligomenorrhea (HP:0000876)2.70466499
25Abnormal urine output (HP:0012590)2.69215088
26Supernumerary spleens (HP:0009799)2.64190283
27Abnormality of dental color (HP:0011073)2.63007280
28Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.58597965
29Degeneration of the lateral corticospinal tracts (HP:0002314)2.58597965
30Anencephaly (HP:0002323)2.55776526
31Pancreatic fibrosis (HP:0100732)2.55106321
32Abnormality of renal excretion (HP:0011036)2.53320584
33Absent rod-and cone-mediated responses on ERG (HP:0007688)2.53101914
34Elevated erythrocyte sedimentation rate (HP:0003565)2.52013718
35Colon cancer (HP:0003003)2.51096491
36Abnormality of the corticospinal tract (HP:0002492)2.47965977
37Partial duplication of the phalanx of hand (HP:0009999)2.47291700
38Abnormality of the labia minora (HP:0012880)2.47286082
39Oculomotor apraxia (HP:0000657)2.45929105
40Narrow forehead (HP:0000341)2.45891642
41Autoimmune thrombocytopenia (HP:0001973)2.44871100
42Abnormality of the renal medulla (HP:0100957)2.40999082
43Entropion (HP:0000621)2.40211238
44Rectal fistula (HP:0100590)2.34659056
45Rectovaginal fistula (HP:0000143)2.34659056
46Amelogenesis imperfecta (HP:0000705)2.33760689
47Bulbous nose (HP:0000414)2.33524031
48Asplenia (HP:0001746)2.30959737
49Bifid tongue (HP:0010297)2.29452356
50Failure to thrive in infancy (HP:0001531)2.27661358
51Impaired vibration sensation in the lower limbs (HP:0002166)2.25201245
523-Methylglutaconic aciduria (HP:0003535)2.24497826
53Vaginal fistula (HP:0004320)2.22689565
54Squamous cell carcinoma (HP:0002860)2.22251941
55Oligohydramnios (HP:0001562)2.20169561
56Ectopic kidney (HP:0000086)2.17581969
57Aplasia/Hypoplasia of the spleen (HP:0010451)2.16906631
58Aplasia/Hypoplasia of the tibia (HP:0005772)2.16519471
59Amyotrophic lateral sclerosis (HP:0007354)2.16451078
60Intestinal fistula (HP:0100819)2.13387901
61Anomalous pulmonary venous return (HP:0010772)2.13067549
62Stomach cancer (HP:0012126)2.12274807
63Reduced antithrombin III activity (HP:0001976)2.11961073
64Epileptic encephalopathy (HP:0200134)2.10083206
65Abolished electroretinogram (ERG) (HP:0000550)2.08492191
66Parakeratosis (HP:0001036)2.03945623
67Alkalosis (HP:0001948)2.02789713
68Abnormality of alanine metabolism (HP:0010916)2.01671377
69Hyperalaninemia (HP:0003348)2.01671377
70Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.01671377
71Pachygyria (HP:0001302)2.00824928
72Increased corneal curvature (HP:0100692)2.00746748
73Keratoconus (HP:0000563)2.00746748
74Thyroid-stimulating hormone excess (HP:0002925)1.96693307
75Congenital stationary night blindness (HP:0007642)1.96208291
76Humeroradial synostosis (HP:0003041)1.94790236
77Synostosis involving the elbow (HP:0003938)1.94790236
78Chronic hepatic failure (HP:0100626)1.92433135
79Stomatitis (HP:0010280)1.90736216
80Generalized hypotonia (HP:0001290)1.88330958
81Abnormality of the lower motor neuron (HP:0002366)1.88161139
82Proximal tubulopathy (HP:0000114)1.86781095
83Anophthalmia (HP:0000528)1.86644015
84Abnormality of the pulmonary veins (HP:0011718)1.86403439
85Adactyly (HP:0009776)1.82485575
86Hypoplasia of the brainstem (HP:0002365)1.81937424
87Aplasia/Hypoplasia of the brainstem (HP:0007362)1.81937424
88Abnormality of the prostate (HP:0008775)1.81683408
89Abnormal ciliary motility (HP:0012262)1.80457063
90Abnormality of the phalanges of the 2nd finger (HP:0009541)1.80075733
91Cystic liver disease (HP:0006706)1.79919897
92Panhypogammaglobulinemia (HP:0003139)1.78977368
93Abnormality of DNA repair (HP:0003254)1.78285774
94Short thumb (HP:0009778)1.77566477
95Postaxial foot polydactyly (HP:0001830)1.76072514
96Poikiloderma (HP:0001029)1.74612082
97Type II lissencephaly (HP:0007260)1.74500649
98Abnormality of purine metabolism (HP:0004352)1.73298577
99Sloping forehead (HP:0000340)1.71868386
100Abnormal drinking behavior (HP:0030082)1.70885901

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST43.70848398
2WNK33.11138191
3FLT32.97982255
4BMPR22.80554965
5ZAK2.80530539
6KIT2.79912975
7MAP2K72.71822835
8FRK2.63183289
9INSRR2.59661691
10MAP4K22.40064034
11NUAK12.37655400
12MAPK132.19758180
13TLK12.05376463
14DYRK21.96727998
15TNIK1.96724405
16ADRBK21.88994088
17PLK21.78292039
18WNK41.76929470
19TEC1.70371167
20CSNK1G21.63876043
21SIK21.56246272
22STK391.43258472
23MARK11.35736381
24NEK21.29979902
25CSNK1G31.29044041
26CSNK1A1L1.27507383
27GRK11.24325815
28FGFR21.22621951
29NTRK21.20082329
30PNCK1.19758485
31TESK21.17875330
32CSF1R1.16681859
33PDK21.16194865
34PHKG11.07990672
35PHKG21.07990672
36RPS6KA51.02585502
37TXK0.99269014
38PINK10.97499301
39FES0.96890285
40CAMKK20.96267996
41UHMK10.94539533
42CSNK1G10.92711833
43IKBKB0.92595070
44ERBB30.91868407
45MAP3K40.91212155
46PLK40.90726886
47EIF2AK30.90706064
48PKN10.83043665
49IRAK40.82424062
50VRK10.81513697
51DMPK0.79113100
52CHEK20.76569457
53CSK0.72108546
54RPS6KA40.71598142
55MAP3K110.69906396
56ATR0.68000230
57PRKCE0.67154676
58GRK50.65647866
59RPS6KA20.63433740
60WNK10.63256868
61ADRBK10.62456503
62MAPK120.61302691
63NME20.60288977
64PRKDC0.58393905
65PIK3CA0.58041900
66DYRK1A0.53892740
67BUB10.53836663
68RPS6KA60.53674135
69VRK20.52688357
70EIF2AK20.51532994
71MAPK70.51521476
72MAP4K10.51443564
73SGK10.51094458
74OXSR10.50795494
75PRKCQ0.50427444
76TAF10.50417249
77PIK3CG0.50114969
78PLK30.49991263
79ERBB20.49944947
80ITK0.46878104
81SYK0.46392741
82STK240.46045592
83MUSK0.45979708
84ATM0.44692396
85PRKCG0.44090223
86BMPR1B0.43119294
87DAPK20.40766139
88CSNK1A10.40364388
89LCK0.40263755
90MAPK110.39976288
91TYRO30.39005636
92PRKACA0.37947913
93MINK10.37358040
94PRKG10.37176890
95ILK0.37124539
96ALK0.36819562
97BTK0.35861427
98PRKCZ0.35462289
99CDK90.35406329
100CDK30.35308435

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053106.24945975
2Allograft rejection_Homo sapiens_hsa053305.17399504
3Graft-versus-host disease_Homo sapiens_hsa053324.88359569
4Autoimmune thyroid disease_Homo sapiens_hsa053204.83803271
5Type I diabetes mellitus_Homo sapiens_hsa049404.64079505
6Intestinal immune network for IgA production_Homo sapiens_hsa046724.05793754
7Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.65990809
8Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.20361886
9Antigen processing and presentation_Homo sapiens_hsa046122.09856976
10Hematopoietic cell lineage_Homo sapiens_hsa046402.07732316
11Staphylococcus aureus infection_Homo sapiens_hsa051502.06731528
12Rheumatoid arthritis_Homo sapiens_hsa053231.96808262
13Viral myocarditis_Homo sapiens_hsa054161.87691693
14alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.44348028
15Phototransduction_Homo sapiens_hsa047441.35202319
16Leishmaniasis_Homo sapiens_hsa051401.32587063
17Butanoate metabolism_Homo sapiens_hsa006501.28354986
18Nicotine addiction_Homo sapiens_hsa050331.26670180
19Oxidative phosphorylation_Homo sapiens_hsa001901.11640371
20Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.09226912
21Linoleic acid metabolism_Homo sapiens_hsa005911.04052972
22Protein export_Homo sapiens_hsa030601.03385177
23Tryptophan metabolism_Homo sapiens_hsa003801.00716480
24Fanconi anemia pathway_Homo sapiens_hsa034600.95816962
25Propanoate metabolism_Homo sapiens_hsa006400.89629645
26Ribosome_Homo sapiens_hsa030100.89370914
27Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86889396
28Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.84944338
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.82833958
30Proteasome_Homo sapiens_hsa030500.81796032
31Systemic lupus erythematosus_Homo sapiens_hsa053220.80684533
32Fatty acid biosynthesis_Homo sapiens_hsa000610.78895580
33Parkinsons disease_Homo sapiens_hsa050120.76748379
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75807771
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.75715795
36Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.71333123
37Base excision repair_Homo sapiens_hsa034100.69541439
38Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.67991571
39Ether lipid metabolism_Homo sapiens_hsa005650.67936289
40Fatty acid degradation_Homo sapiens_hsa000710.67501019
41Cardiac muscle contraction_Homo sapiens_hsa042600.61941472
42Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.61545432
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.59228031
44Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59066076
45Fatty acid metabolism_Homo sapiens_hsa012120.58630494
46Tuberculosis_Homo sapiens_hsa051520.58625897
47Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.58492123
48Basal transcription factors_Homo sapiens_hsa030220.57243343
49Arachidonic acid metabolism_Homo sapiens_hsa005900.56967026
50Jak-STAT signaling pathway_Homo sapiens_hsa046300.56096202
51Caffeine metabolism_Homo sapiens_hsa002320.54425600
52Huntingtons disease_Homo sapiens_hsa050160.52033403
53Alzheimers disease_Homo sapiens_hsa050100.51841540
54Chemical carcinogenesis_Homo sapiens_hsa052040.51192915
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.51085216
56Herpes simplex infection_Homo sapiens_hsa051680.50922021
57Steroid biosynthesis_Homo sapiens_hsa001000.48051864
58Toxoplasmosis_Homo sapiens_hsa051450.47958685
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.47845350
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.47805221
61Peroxisome_Homo sapiens_hsa041460.47686384
62Phagosome_Homo sapiens_hsa041450.46430565
63beta-Alanine metabolism_Homo sapiens_hsa004100.46246281
64RNA polymerase_Homo sapiens_hsa030200.43616194
65PPAR signaling pathway_Homo sapiens_hsa033200.42715356
66Primary immunodeficiency_Homo sapiens_hsa053400.41196938
67Olfactory transduction_Homo sapiens_hsa047400.40883826
68Homologous recombination_Homo sapiens_hsa034400.40321550
69Taste transduction_Homo sapiens_hsa047420.39553420
70Fat digestion and absorption_Homo sapiens_hsa049750.38998451
71Sphingolipid metabolism_Homo sapiens_hsa006000.38680651
72RNA degradation_Homo sapiens_hsa030180.38533712
73Nitrogen metabolism_Homo sapiens_hsa009100.38312929
74Morphine addiction_Homo sapiens_hsa050320.35088349
75GABAergic synapse_Homo sapiens_hsa047270.31902910
76Salivary secretion_Homo sapiens_hsa049700.31094194
77Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.31009116
78Serotonergic synapse_Homo sapiens_hsa047260.30509663
79Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30325043
80Influenza A_Homo sapiens_hsa051640.29725686
81Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.26272684
82Retinol metabolism_Homo sapiens_hsa008300.25867650
83Glutathione metabolism_Homo sapiens_hsa004800.25449022
84Dorso-ventral axis formation_Homo sapiens_hsa043200.25340626
85Circadian entrainment_Homo sapiens_hsa047130.25008035
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.24864215
87Glutamatergic synapse_Homo sapiens_hsa047240.22622978
88Circadian rhythm_Homo sapiens_hsa047100.22121376
89Pyrimidine metabolism_Homo sapiens_hsa002400.21833397
90Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.20035690
91Vascular smooth muscle contraction_Homo sapiens_hsa042700.19746773
92Nucleotide excision repair_Homo sapiens_hsa034200.19398946
93Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.18964696
94Lysine degradation_Homo sapiens_hsa003100.18053317
95HTLV-I infection_Homo sapiens_hsa051660.17332906
96Starch and sucrose metabolism_Homo sapiens_hsa005000.15363048
972-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.15214012
98Metabolic pathways_Homo sapiens_hsa011000.15200919
99Cocaine addiction_Homo sapiens_hsa050300.15163489
100Type II diabetes mellitus_Homo sapiens_hsa049300.13716354

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »